ACB: PI3K/AKT/mTOR/Sonic Hedgehog Pathway Inhibitor

“PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit cancer and tumor growth.”

“Cancer Cell Signaling Pathways Targeted by Spice-Derived Nutraceuticals”

“Regulation of cell signaling pathways by dietary agents for cancer prevention and treatment”

“Inhibition of PI3K/Akt/mTOR Signaling by Natural Products”

“mTOR Inhibition: From Aging to Autism and Beyond“

From wiki: “The PI3K/AKT/mTOR pathway is an intracellular signaling pathway important in regulating the cell cycle. Therefore, it is directly related to cellular quiescence, proliferation, cancer, and longevity. PI3Kactivation phosphorylates and activates AKT, localizing it in the plasma membrane.^[1] AKT can have a number of downstream effects such as activating CREB,^[2] inhibiting p27,^[3] localizing FOXO in the cytoplasm,^[3] activating PtdIns-3ps,^[4] and activating mTOR^[3] which can affect transcription of p70 or 4EBP1.^[3] There are many known factors that enhance the PI3K/AKT pathway including EGF,^[5]shh,^[2] IGF-1,^[2] insulin,^[3] and CaM.^[4] The pathway is antagonized by various factors including PTEN,^[6]GSK3B,^[2] and HB9.^[5] In many cancers, this pathway is overactive, thus reducing apoptosis and allowing proliferation.”

”The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult. Diseases associated with the malfunction of this pathway include basal cell carcinoma.^[1]

FEATURING: •Aegle marmelos Correa • Agaricus blazei Murill • Aloe emodin • American ginseng extract • Andrographolide • Angelica archangelica • Angelica sinensis extract • Bilberry extract Anthocyanin • Antrodia cinnamomea • Artemisinin Artemisia annua L. (Huanghuahao) • Artepillin C (Brazilian propolis) • Ashwagandha • Astragalus membranaceus extract • Belamcanda chinensis • Berberine (Cortidis rhizoma) • Camellia sinensis • Carnosine • Carnosol • Cat’s Claw (Uncaria tomentosa) • Catharantus roseus • Celastrol (derived from Trypterygium wilfordii) • Celastrus Orbiculatus • Chenopodium ambrosioides L • Cinnamomum cassia • Commiphora myrrha • Coprinus comatus • Corchorus olitorius • Cordycepin • Cordyceps militaris • Crocus sativus (Saffron) • Curcuma wenyujin • Curcumin • Cycloastragenol • Cynara cardunculus • Dalbergia odorifera • EGCG • Eleutherococcus senticosus • Emblica officinalis • Epimedium koreanum • Euonymus alatus • Flammulina velutipes (enokitake) • Fomes fomentarius • Frankincense (Boswellia carteri) • Fucus vesiculosus (seaweed) • Gambogic acid (Garcinia hanburyi) • Ganoderma lucidum • Ganoderma tsugae • Genistein • Ginkgo Biloba • Ginseng extract• ginsenoside Rh • Glycyrrhiza glabra • Grape Seed Extract • Grifola frondosa — Maitake • Gynostemma pentaphylla extract • Hedyotis Diffusa Willd extract • Hericium erinaceus — Lions mane • Hibiscus sabdariffa • Honokiol • Humulone • Icariin • Inonotus obliquus — Chaga • Lactarius flavidulus • Lapacho (Tabebuia impetiginosa) • Lithospermum erythrorhizon • Livistona chinensis • Lupeol • Luteolin • Lycium barbarum—Wolfberry (goji) • Lycopene • Magnolia officinalis (Chinese magnolia tree) • Mangiferin (Mangifera indica) • Momordica cochinchinensis Spreng • Moringa oleifera • Noni (Morinda citrifolia) • Ocimum gratissimum oil • Oldenlandia diffusa • Oleanolic acid • Oleuropein • Orthosiphon Stamineus • Osthol (Cnidium monnieri) • Oyster extract • Panax notoginseng extract • Patrinia scabiosaefolia • Pfaffia paniculata —Brazilian Ginseng (Suma) • Phellinus linteus • Phycocyanin • Phyllanthus urinaria • Pleurotus ostreatus • Pleurotus pulmonarius • Plumbago zeylanica L • Podophyllotoxin (Podophyllyum emodi) • Polygonum cuspidatum • Polyozellus multiplex • Poria cocos • Prunella vulgaris extract • Punica granatum (pomegranate) • Punicalagin (from pomegranate extract) • Quercetin • Rabdosia rubescens • Reineckia carnea (RCE ) • Resveratrol • Rhodiola rosea • Rhus verniciflua • Russula lepida • Salvia miltiorrhiza extract • Salvia officinalis • Schizophyllum commune • Scrophularia ningpoensis • Scutellaria baicalensis Georgi • Scutellaria barbata • Sea Cucumber (Cucumaria frondos) • Shiitake— Lentinula edodes mycelia extract • Silymarin• a flavonolignan from milk thistle (Silybum marianum) • Strychnos nux vomica L extract • Thymoquinone (Nigella sativa) • Trifolium pratense L. • Turkey tail mushroom —Trametesversicolor orCoriolusversicolor • Ursolic acid • Wedelia chinensis • Wogonin (Scutellariae radix) • Xanthohumol • Zerumbone (From Zingiber zerumbet) • Zingiber officinale Roscoe • Zizyphus mauritiana

WARNING: As with any supplement, consult your medical practitioner prior to using this product if you are pregnant, may become pregnant, breastfeeding, taking medication, other dietary supplements or have a medical condition. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

*Daily Value has not been established

ACB 

200:1 CONCENTRATION

”It’s like firing 125 arrows at the bullseye—one is bound to hit the mark.” 

100g = 300 1/8 tsp servings

In stock and shipping now!

Aegle marmelos yCorrea

1. In vitro antiproliferative effects on human tumor cell lines of extracts from the Bangladeshi medicinal plant Aegle marmelos Correa
2. Antioxidant and hepatoprotective potential of Aegle marmelos Correa. against CCl4-induced oxidative stress and early tumor events
3. Taxol, an anticancer drug produced by an endophytic fungus Bartalinia robillardoides Tassi, isolated from a medicinal plant, Aegle marmelos Correa ex Roxb.
4. Radioprotective Effects of Aegle marmelos (L.) Correa (Bael): A Concise Review
5. A study of hypoglycemic and antioxidant activity of Aegle marmelos in alloxan induced diabetic rats
6. Fruit extract of Aegle marmelos protects mice against radiation-induced lethality
7. Hepatoprotective effect of the pulp/seed of Aegle marmelos correa ex Roxb against carbon tetrachloride induced liver damage in rats
8. Aegle marmelos (L.) Correa (Bael) and Its Phytochemicals in the Treatment and Prevention of Cancer
9. Healing effects of Aegle marmelos (L.) Correa fruit extract on experimental colitis
10. Effect of Aegle marmelos Correa. (Bael) fruit extract on tissue antioxidants in streptozotocin diabetic rats
11. Antioxidant, anticancer, antibacterial activities and GC-MS analysis of aqueous extract of pulps of Aegle marmelos (L.) Correa
12. Evaluation of Aegle marmelos L. Fruit Extract in Reduction of Mobile Phone Induced Oxidative Stress in Mice, Mus musculus
13. Aegle marmelos (L.) CORREA Inhibits the Proliferation of Transplanted Ehrlich Ascites Carcinoma in Mice
14. Aegle marmelos and Emblica officinalis, used in traditional Asian medicine in the treatment of tissue inflammation and cancer. To this aim, we evaluated the potential of the selected plant extracts to affect proliferation and differentiation of ERα-negative MDA-MB-231 breast cancer cells,
15. Therapeutic potential of Aegle marmelos (L.)-An overview
16. Aegle marmelos (L.) Correa (Bael) and Its Phytochemicals in the Treatment and Prevention of Cancer
17. Isolation and characterization of bioactive metabolites from Xylaria psidii, an endophytic fungus of the medicinal plant Aegle marmelos and their role in mitochondrial dependent apoptosis against pancreatic cancer cells
18. Effect of Aegle marmelos leaf extract on N-methyl N-nitrosourea-induced hepatocarcinogensis in Balb/c mice
19. Pharmacognostic standardisation and antiproliferative activity of Aegle marmelos (L.) Correa leaves in various human cancer cell lines
20. Aegle Marmelos In this work the extraction of the Aegeline is taken up along with the separation of its enantiomers, its crystal structure
    and activity of individual isomers on cervical cancer
21. Aegle marmelos … to treat cancer) has been shown to increase the
    level and function of natural killer cells in cervical cancer patients undergoing
22. (Aegle marmelos) leaves and … The nanoparticles were tested for cytotoxicity
    on two human cancer cell lines, HeLa (human cervical cancer)

Agaricus blazei Murill

1. Tumor-specific cytocidal and immunopotentiating effects of relatively low molecular weight products derived from the basidiomycete, Agaricus blazei Murill.
2. Isolation of an antitumor compound from Agaricus blazei Murill and its mechanism of action
3. Selective tumoricidal effect of soluble proteoglucan extracted from the basidiomycete, Agaricus blazei Murill, mediated via natural killer cell activation and apoptosis
4. Quality of life were improved by consumption of a mushroom extract, Agaricus blazei Murill Kyowa, in gynecological cancer patients undergoing chemotherapy
5. Effects of the medicinal mushroom Agaricus blazei Murill on immunity, infection and cancer
6. Inhibition by Agaricus blazei Murill fractions of cytopathic effect induced by western equine encephalitis (WEE) virus on VERO cells in vitro
7. Secretion of TNF-α, IL-8 and nitric oxide by macrophages activated with Agaricus blazei Murill fractions in vitro
8. Suppressing effects of daily oral supplementation of beta-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis
9. Isolation of an anti‐angiogenic substance from Agaricus blazei Murill: Its antitumor and antimetastatic actions
10. The mushroom Agaricus blazei Murill elicits medicinal effects on tumor, infection, allergy, and inflammation
11. The Polar High Molecular Weight Fraction of the Agaricus blazei Murill Extract, AndoSan™, Reduces the Activity of the Tumor-Associated Protease
12. Influences of the Extract of Agaricus Blazei Murill on Hepatitis, Cancer and Immunity
13. Inhibitory mechanisms of Agaricus blazei Murill on the growth of prostate cancer in vitro and in vivo
14. An Alternative Medicine, Agaricus blazei, May Have Induced Severe Hepatic Dysfunction in Cancer Patients
15. Measuring perceived effects of drinking an extract of basidiomycetes Agaricus blazei murill: a survey of Japanese consumers with cancer
16. A novel medicinal mushroom blend which consists of a blend of mushroom mycelia from the species Agaricus blazei, demonstrates cytostatic effects through the inhibition of cell proliferation and cell cycle arrest at the G2/M phase of highly invasive human breast cancer cells
17. Antitumor effects of a new polysaccharide-protein complex (ATOM) prepared from Agaricus blazei (Iwade strain 101) “Himematsutake” and its mechanisms in tumor-bearing mice.
18. Medicinal Properties and Clinical Effects of Culinary-Medicinal Mushroom Agaricus blazei Murrill (Agaricomycetideae) (Review)
19. Effect of water-soluble proteoglycan isolated from Agaricus blazei on the maturation of murine bone marrow-derived dendritic cells
20. The effects of dietary supplementation with Agaricales mushrooms and other medicinal fungi on breast cancer: evidence-based medicine
21. Hot water extract of Agaricus blazei Murrill specifically inhibits growth and induces apoptosis in human pancreatic cancer cells
22. Anti-cancer Property of Aegle marmelos Leaves: Finding the Facts Against Hepatocellular Carcinoma HepG2 cell.
23. Nontargeted analysis and cancer cells cytotoxicity of Aegle marmelos Correa Ex Roxb.
24. ANTI-MICROBIAL AND ANTI-CANCER ACTIVITY OF AEGLE MARMELOS AND GAS CHROMATOGRAPHY COUPLED SPECTROMETRY ANALYSIS OF THEIR CHEMICAL CONSTITUENTS
25. A xylorhamnoarabinogalactan I from Bael (Aegle marmelos L.) modulates UV/DMBA induced skin cancer via galectin-3 & gut microbiota
26. Anticancer ability of Jamur Dewa Extract (Agaricus blazei Murill) On Cervical
    Cancer cells as a Reading Material For Traditional Medicine.
27. which included 61 cervical cancer patients, stages Ia–IIIb, received either carboplatin and etoposide or carboplatin and Taxol every 3 weeks with or without oral Agaricus blazei (as Agaricus blazei Murill
28. Immunomodulatory Effects of the Agaricus blazei Murrill-Based Mushroom Extract AndoSan in Patients with Multiple Myeloma Undergoing High Dose Chemotherapy and Autologous Stem Cell Transplantation: A Randomized, Double Blinded Clinical Study
29. The Agaricus blazei-based mushroom extract, AndosanTM, has immuno-suppressive and anti-inflammatory effects when used as supplement to multiple myeloma patients receiving high-dose chemotherapy and autologous bone marrow transplantation
30. Antitumor and immunomodulating effects of the mushroom product AndosanTM, based on the Basidiomycetes mushroom Agaricus blazei Murill, with special focus on multiple myeloma

Aloe emodin

1. Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma
2. Protein kinase C involvement in aloe‐emodin‐and emodin‐induced apoptosis in lung carcinoma cell
3. Combined effect of aloe-emodin and chemotherapeutic agents on the proliferation of an adherent variant cell line of Merkel cell carcinoma
4. Aloe-emodin is a new type of anticancer agent with selective activity against neuroectodermal tumors
5. The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines
6. Aloe-emodin induces cell death through S-phase arrest and caspase-dependent pathways in human tongue squamous cancer SCC-4 cells
7. Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation
8. The effect of aloe emodin on the proliferation of a new merkel carcinoma cell line
9. Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells
10. Evaluation of the anti-angiogenic effect of aloe-emodin
11. Suppressed Transformation and Induced Differentiation of HER-2/neu-overexpressing Breast Cancer Cells by Emodin
12. Tyrosine Kinase Inhibitor Emodin Suppresses Growth of HER-2/neu-overexpressing Breast Cancer Cells in Athymic Mice and Sensitizes These Cells to the Inhibitory Effect of Paclitaxel
13. Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ERα Inhibition
14. Silk fibroin mediated delivery of liposomal emodin to breast cancer cells
15. Synergistic effects of curcumin with emodin against the proliferation and invasion of breast cancer cells through upregulation of miR-34a
16. Emodin Down-Regulates Androgen Receptor and Inhibits Prostate Cancer Cell Growth
17. Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: The mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1
18. Emodin induces apoptosis in human prostate cancer cell LNCaP
19. Aloe-emodin suppresses prostate cancer by targeting the mTOR complex 2
20. Emodin inhibits invasion and migration of prostate and lung cancer cells by downregulating the expression of chemokine receptor CXCR4
21. Aloe-Emodin Protects RIN-5F (Pancreatic β-cell) Cell from Glucotoxicity via Regulation of Pro-Inflammatory Cytokine and Downregulation of Bax and Caspase 3
22. Erratum to “Aloe-Emodin Protects RIN-5F (Pancreatic β-cell) Cell from Glucotoxicity via Regulation of Pro-Inflammatory Cytokine and Downregulation of Bax and Caspase 3”
23. Aloe emodin exerts potent anticancer effects in MIAPaCa-2 and PANC-1 human pancreatic adenocarcinoma cell lines through activation of both apoptotic and autophagic pathways, sub-G1 cell cycle arrest and disruption of mitochondrial membrane potential (ΛΨm)
24. Photodynamic activity of aloe-emodin induces resensitization of lung cancer cells to anoikis
25. Protein Kinase C Delta-mediated Cytoskeleton Remodeling Is Involved in Aloe-emodin-induced Photokilling of Human lung cancer Cells
26. Abstract 133: Aloe-emodin as a potential lead targets lung cancer stem cells
27. P-052 Aloe-emodin inhibit n-acetyltransferase activity and geneexpression in human lung cancer cell line (NCI-H209)
28. Glycosylated Aloe Emodin Inhibits the Growth of Human lung cancer Cells in vitro and in vivo
29. Aloe emodin inhibits colon cancer cell migration/angiogenesis by downregulating MMP-2/9, RhoB and VEGF via reduced DNA binding activity of NF-κB
30. Aloe Emodin Induces G2/M Cell Cycle Arrest and Apoptosis via Activation of Caspase-6 in Human colon cancer Cells
31. The Effect of Aloe-emodin on Multiplication Cycle and Apoptosis of Colon Carcinoma Cancer Cell SW480
32. Aloe-Emodin Induces Endoplasmic Reticulum Stress-Dependent Apoptosis in colorectal cancer Cells
33. Aloe-emodin induced in vitro G2/M arrest of cell cycle in human promyelocytic leukemia HL-60 cells
34. Aloe-emodin inhibited N-acetylation and DNA adduct of 2-aminofluorene and arylamine N-acetyltransferase gene expression in mouse leukemia L 1210 cells
35. Aloe-emodin as antiproliferative and differentiating agent on human U937 monoblastic leukemia cells
36. Studies of the interaction between Aloe-emodin and DNA and preparation of DNA biosensor for detection of PML-RARα fusion gene in acute promyelocytic leukemia
37. Pro-apoptic effect of Aloe emodin on human thyroid cancer cell K1.
38. Emodin impairs radioresistance of human osteosarcoma cells by suppressing sonic Hedgehog signaling
39. Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation
40. Emodin induces apoptosis of human cervical cancer hela cells via intrinsic mitochondrial and extrinsic death receptor pathway
41. Curcumin and Emodin Down-Regulate TGF-β Signaling Pathway in Human Cervical Cancer Cells
42. Combination of aloe-emodin with radiation enhances radiation effects and improves differentiation in human cervical cancer cells
43. Emodin Induces Apoptosis of Human Tongue Squamous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways
44. Anticancer potential of emodin
45. Emodin, Aloe-emodin and Rhein Induced DNA Damage and Inhibited DNA Repair Gene Expression in SCC-4 Human Tongue Cancer Cells
46. The distinct mechanisms of the antitumor activity of emodin in different types of cancer (Review)
47. [Inhibitory effect of emodin on the growth of cervical cancer in tumor-transplanted mice and underlying mechanism].
48. Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9
49. Effects and mechanisms of emodin on cell death in human lung squamous cell carcinoma
50. Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma
51. Aloe-emodin (AE) nanoparticles suppresses proliferation and induces apoptosis in human lung squamous carcinoma via ROS generation in vitro and in vivo
52. [Effect of emodin on proliferation and cell cycle of human oral squamous carcinoma Tca8113 cells in vitro].
53. Emodin, Physcion, and Crude Extract of Rhamnus sphaerosperma var. pubescens Induce Mixed Cell Death, Increase in Oxidative Stress, DNA Damage, and Inhibition of AKT in Cervical and Oral Squamous Carcinoma Cell Lines
54. Emodin has a cytotoxic activity against human multiple myeloma as a Janus-activated kinase 2 inhibitor
55. [Inhibitory and Inducing Effects of Emodin Derivative E11 on Proliferation and Apoptosis of Multiple Myeloma Cells].

American ginseng extract

1. American ginseng: potential structure–function relationship in cancer chemoprevention
2. Pilot study of Panax quinquefolius (American ginseng) to improve cancer-related fatigue: a randomized, double-blind, dose-finding evaluation: NCCTG trial N03CA
3. Red American ginseng: ginsenoside constituents and antiproliferative activities of heat-processed Panax quinquefolius roots
4. American ginseng and breast cancer therapeutic agents synergistically inhibit MCF‐7 breast cancer cell growth
5. Anti-proliferative effect of ginseng saponins on human prostate cancer cell line
6. Preventive effect of ginseng intake against various human cancers: a case-control study on 1987 pairs.
7. Cisplatin’s tumoricidal effect on human breast carcinoma MCF-7 cells was not attenuated by American ginseng
8. Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells
9. Extraction-dependent effects of American ginseng (Panax quinquefolium) on human breast cancer cell proliferation and estrogen receptor activation
10. Panax ginseng—a non-organ-specific cancer preventive?
11. Stereospecific anticancer effects of ginsenoside Rg3 epimers isolated from heat-processed American ginseng on human gastric cancer cell
12. Rh2 from Ginseng Synergistically Enhances Paclitaxel or Mitoxantrone in Prostate Cancer Models
13. Generation of ginsenosides Rg3 and Rh2 from North American ginseng
14. Experimental therapy of prostate cancer with novel natural product anti‐cancer ginsenosides
15. Protective Effects of Asian Dietary Items on Cancers – Soyand Ginseng
16. Extraction-Dependent Effects of American Ginseng (Panax quinquefolium) on Human Breast Cancer Cell Proliferation and Estrogen Receptor Activation
17. American Ginseng Transcriptionally Activates p21mRNA in BreastCancer Cell Lines
18. American Ginseng Inhibits Induced COX-2 and NFKB Activation in Breast Cancer Cells
19. Chemical and pharmacological studies of saponins with a focus on American ginseng
20. The influence of lead and arsenite on the inhibition of human breast cancer MCF-7 cell proliferation by American ginseng root (Panax quinquefolius L.)
21. Uses of north american ginseng fractions for treating leukemia
22. American ginseng and its interactions with Imatinib mesylate (Gleevec) on K562 chronic myeloid leukemia cells
23. The mitochondrial pathway is involved in American ginseng-induced apoptosis of SW-480 colon cancer cells
24. American ginseng suppresses Western diet-promoted tumorigenesis in model of inflammation-associated colon cancer: role of EGFR
25. Role of cyclin inhibitor protein p21 in the inhibition of HCT116 human colon cancer cell proliferation by American ginseng (Panax quinquefolius) and its constituents
26. A Key Role of microRNA-29b for the Suppression of colon cancer Cell Migration by American Ginseng
27. Mechanistic insight into the ability of American ginseng to suppress colon cancer associated with colitis
28. A Hexane Fraction of American Ginseng Suppresses Mouse Colitis and Associated colon cancer: Anti-inflammatory and Proapoptotic Mechanisms
29. Metabonomic Profiling Reveals Cancer Chemopreventive Effects of American Ginseng on Colon Carcinogenesis in ApcMin/+ Mice
30. Role of intestinal microbiome in American ginseng-mediated colon cancer protection in high fat diet-fed AOM/DSS mice
31. Hexane Fraction of American Ginseng Suppresses Colitis and colon cancer—Letter
32. Red American ginseng enhances the effect of fluorouracil on human colon cancer cells via both paraptosis and apoptosis pathways
33. Hexane Fraction of American Ginseng Suppresses Colitis and colon cancer—Response
34. Abstract 1248: Gut microbiome and metabolomic profiling reveal preventive effects of American ginseng on inflammation-associated colon cancer
35. Antioxidants potentiate American ginseng-induced killing of colorectal cancer cells
36. Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells
37. American ginseng berry enhances chemopreventive effect of 5-FU on human colorectal cancer cells
38. [Progress in anti-cancer research of American ginseng: with an example of colorectal cancer].
39. Abstract B28: Chemoprevention of colorectal cancer: Does American ginseng play a role?
40. Abstract LB-168: A hexane fraction of American ginseng suppresses colon cancer associated with colitis
41. Ginseng and cancer
42. Effect of sun ginseng potentiation on epirubicin and paclitaxel-induced apoptosis in human cervical cancer cells
43. Functional role of ginseng-derived compounds in cancer
44. Potential Anti-Cancer Activities of Furanodiene, A Sesquiterpene from Curcuma wenyujin
45. Improved anticancer effect of ginseng extract by microwave-assisted processing through the generation of ginsenosides Rg3, Rg5 and Rk1
46. Ginseng nanoparticles: a budding tool for cancer treatment
47. Determination of Ginsenosides Content in Korean Ginseng Seeds and Roots by High Performance Liquid Chromatography
48. Notoginsenoside R7 suppresses cervical cancer via PI3K/PTEN/Akt/mTOR signaling
49. Ginsenoside‑Rg5 induces apoptosis and DNA damage in human cervical cancer cells
50. Ginseng: A medical Enigma

Andrographolide

1. Inhibitory effects of andrographolide on migration and invasion in human non-small cell lung cancer A549 cells via down-regulation of PI3K/Akt signaling pathway
2. Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata
3. Apoptosis inducing effect of andrographolide on TF-47 human breast cancer cell line
4. Andrographolide and its analogues: versatile bioactive molecules for combating inflammation and cancer
5. DRF 3188 a novel semi-synthetic analog of andrographolide: cellular response to MCF 7 breast cancer cells
6. Andrographolide, an herbal medicine, inhibits interleukin-6 expression and suppresses prostate cancer cell growth
7. The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma
8. Benzylidene derivatives of andrographolide inhibit growth of breast and colon cancer cells in vitro by inducing G1 arrest and apoptosis
9. Andrographolide inhibits the adhesion of gastric cancer cells to endothelial cells by blocking E-selectin expression
10. Andrographolide down-regulates hypoxia-inducible factor-1α in human non-small cell lung cancer A549 cells
11. Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells
12. Andrographolide inhibits hypoxia-inducible factor-1 through phosphatidylinositol 3-kinase/AKT pathway and suppresses breast cancer growth
13. Benzylidene derivatives of andrographolide inhibit growth of breast and colon cancer cells in vitro by inducing G1 arrest and apoptosis
14. Cytotoxicity and cell cycle arrest induced by andrographolide lead to programmed cell death of MDA-MB-231 breast cancer cell line
15. Andrographolide and its analogues: versatile bioactive molecules for combating inflammation and cancer
16. Andrographolide, an Herbal Medicine, Inhibits Interleukin-6 Expression and Suppresses Prostate Cancer Cell Growth
17. Andrographolide Targets Androgen Receptor Pathway in Castration-Resistant Prostate Cancer
18. Taxifolin Enhances Andrographolide-Induced Mitotic Arrest and Apoptosis in Human Prostate Cancer Cells via Spindle Assembly Checkpoint Activation
19. Andrographolide induces cell cycle arrest and apoptosis in PC-3 prostate cancer cells
20. Morphological and Biochemical Changes of Andrographolide-induced Cell Death in Human Prostatic Adenocarcinoma PC-3 Cells
21. Andrographolide causes apoptosis via inactivation of STAT3 and Akt and potentiates antitumor activity of gemcitabine in pancreatic cancer
22. The HLJ1 -targeting drug screening identified Chinese herb andrographolide that can suppress tumour growth and invasion in non-small-cell lung cancer
23. Andrographolide inhibits the activation of NF‑κB and MMP‑9 activity in H3255 lung cancer cells
24. SRS06, a New Semisynthetic Andrographolide Derivative with Improved Anticancer Potency and Selectivity, Inhibits Nuclear Factor-κB Nuclear Binding in the A549 Non-Small Cell lung cancer Cell Line
25. Andrographolide enhances cisplatin-mediated anticancer effects in lung cancer cells through blockade of autophagy
26. Effect of Andrographolide on Human lung cancer Cells Proliferation and Invasion-associated Molecular Expression
27. Molecular mechanism of Andrographolide on MMP-9 expression in human lung cancer cells
28. Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment
29. Andrographolide Exhibits Anti-Invasive Activity against colon cancer Cells via Inhibition of MMP2 Activity
30. Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells
31. Andrographolide suppresses proliferation of human colon cancer SW620 cells through the TLR4/NF‑κB/MMP‑9 signaling pathway
32. In vitro 3D colon tumor penetrability of SRJ09, a new anti-cancer andrographolide analog
33. Andrographolide Exhibits Anticancer Potential Against Human colon cancer Cells by Inducing Cell Cycle Arrest and Programmed Cell Death via Augmentation of Intracellular Reactive Oxygen Species Level
34. A silyl andrographolide analogue suppresses Wnt/β-catenin signaling pathway in colon cancer
35. Cytotoxic activity of andrographolide in colon cancer through inhibition cox-2 by in silico study
36. Induction of G1 arrest and apoptosis by new benzylidene derivatives of andrographolide in breast and colon cancer cells
37. Effect of andrographolide in inhibition of human colon cancer SW1116 cell.
38. Anticancer Activity of A Silyl Andrographolide Analogue Mediated Through Wnt/β-Catenin Signaling In colon cancer Cells
39. Andrographolide reversed 5-FU resistance in human colorectal cancer by elevating BAX expression
40. Andrographolide enhanced 5-fluorouracil-induced antitumor effect in colorectal cancer via inhibition of c-MET pathway
41. The anti-cancer activity of an andrographolide analogue functions through a GSK-3β-independent Wnt/β-catenin signaling pathway in colorectal cancer cells
42. Andrographolide Antagonizes TNF-α-Induced IL-8 via Inhibition of NADPH Oxidase/ROS/NF-κB and Src/MAPKs/AP-1 Axis in Human colorectal cancer HCT116 Cells
43. An open-label, randomized, controlled clinical trial to explore the curative effects between the treatment of capecitabine and andrographolide and the single capecitabine in the patients with pathological and/or histologic diagnosed unresectable, advanced, recurrent, and metastatic colorectal cancer.
44. Folate-Functionalized Amphiphilic Chitosan Polymeric Micelles Containing Andrographolide Analogue (3A.1) for colorectal cancer
45. Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways
46. Andrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway
47. Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
48. Andrographolide from Andrographis paniculata shows anti-proliferative activity and anti-inflammatory effects in human monocytic leukemia cells
49. Andrographolide and its potent derivative exhibit anticancer effects against imatinib-resistant chronic myeloid leukemia cells by downregulating the Bcr-Abl oncoprotein
50. Abstract 717: The diterpenoid lactone andrographolide (andro) induces apoptosis in all- trans-retinoic-acid (ATRA) resistant acute promyelocytic leukemia (APL) cell lines: Potential therapeutic implications
51. Andrographolide induces autophagic cell death in human liver cancer cells through cyclophilin D-mediated mitochondrial permeability transition pore
52. In vivo inhibitory activity of andrographolide derivative ADN-9 against liver cancer and its mechanisms involved in inhibition of tumor angiogenesis
53. Andrographolide radiosensitizes human ovarian cancer SKOV3 xenografts due to an enhanced apoptosis and autophagy
54. Anti-proliferative and Pro-apoptotic Effects from Sequenced Combinations of Andrographolide and Cisplatin on ovarian cancer Cell Lines
55. Effects of andrographolide on invasion and apoptosis of ovarian cancer SKOV-3 cells
56. A novel role of andrographolide, an NF-kappa B inhibitor, on inhibition of platelet activation: the pivotal mechanisms of endothelial nitric oxide synthase/cyclic GMP
57. Andrographolide stimulates osteoblastogenesis and bone formation by inhibiting nuclear factor kappa-Β signaling both in vivo and in vitro
58. Effects of rapeseed meal, terramycin, berberine hydrochloride and andrographolide on thyroid function in fattening swine
59. Critical role of pro-apoptotic Bcl-2 family members in andrographolide-induced apoptosis in human cancer cells
60. Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin
61. Activity of Andrographolide and Its Derivatives on HPV16 Pseudovirus Infection and Viral Oncogene Expression in Cervical Carcinoma Cells
62. Andrographolide impedes cancer stemness and enhances radio-sensitivity in oral carcinomas via miR-218 activation
63. Broad-spectrum antiviral properties of andrographolide
64. The effect of andrographolide on Human papillomavirus type 16 (HPV16) positive cervical cancer cells (SiHa)
65. Nanoparticle Engineering Enhances Anticancer Efficacy of Andrographolide in MCF-7 Cells and Mice Bearing EAC
66. Synthesis and evaluation of anticancer activity of novel andrographolide derivatives†
67. Andrographolide: A New Plant-Derived Antineoplastic Entity on Horizon
68. Biodegradable andrographolide-eluting nanofibrous membranes for the treatment of cervical cancer

Angelica archangelica

1. The cytotoxic effect of two chemotypes of essential oils from the fruits of Angelica archangelica L.
2. Antitumour activity of Angelica archangelica leaf extract
3. Antiproliferative effect of Angelica archangelica fruits
4. Antioxidant and flavor properties of Angelica sinensis extracts as affected by processing
5. Study of the antimutagenic properties of Angelica archangelica by the micronucleus test
6. An Update on Antitumor Activity of Angelica Species
7. Antitumour activity of Angelica archangelica leaf extract. – NCBI
8. Antitumour activity of Angelica archangelica leaf extract – ResearchGate
9. Antiproliferative Effect of Angelica archangelica Fruits
10. Antitumour Activity of Angelica archangelica Leaf Extract
11. Enhanced accumulation of decursin and decursinol angelate in root cultures and intact roots of Angelica gigas Nakai following elicitation
12. Angelicin inhibits the malignant behaviours of human cervical cancer potentially via inhibiting autophagy
13. Complementary and Alternative Approach to Heal Cancer: A Review
14. Imperatorin efficiently blocks TNF-α-mediated activation of ROS/PI3K/Akt/NF-κB pathway

Angelica sinensis extract

1. Experimental study of anti-tumor effects of polysaccharides from Angelica sinensis
2. Study of the anti-proliferative effects and synergy of phthalides from Angelica sinensis on colon cancer cells
3. Acetone extract of Angelica sinensis inhibits proliferation of human cancer cells via inducing cell cycle arrest and apoptosis
4. Effect of polysaccharides from Angelica sinensis on gastric ulcer healing
5. A novel polysaccharide, isolated from Angelica sinensis (Oliv.) Diels induces the apoptosis of cervical cancer HeLa cells through an intrinsic apoptotic pathway
6. The antitumor effects of Angelica sinensis on malignant brain tumors in vitro and in vivo
7. Structure of an anti-tumor polysaccharide from Angelica sinensis (Oliv.) Diels
8. The natural compound n‐butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo3
9. Characterizations and anti-tumor activities of three acidic polysaccharides from Angelica sinensis (Oliv.) Diels
10. The angiogenic effects of Angelica sinensis extract on HUVEC in vitro and zebrafish in vivo
11. Potential therapeutic effects of N-butylidenephthalide from Radix Angelica Sinensis (Danggui) in human bladder cancer cells
12. Use of dong quai (Angelica sinensis) to treat peri- or postmenopausal symptoms in women with breast cancer: is it appropriate?
13. Among the top 10 most frequently prescribed CHP for treating breast cancer, seven contained dang qui (Angelica sinensis-radix) and six contained ren shen (Panax ginseng-radix), which are reported to have potential beneficial synergistic effects on breast cancer cells.
14. Estrogenic activity of standardized extract of Angelica sinensis
15. Angelicae sinensis are traditional Chinese herbs, all of which have proven immunomodulatory functions in laboratory‐based research.
16. Epigenetic Reactivation of Nrf2 in Murine Prostate Cancer TRAMP C1 Cells by Natural Phytochemicals Z-Ligustilide and Radix Angelica Sinensis via Promoter CpG Demethylation
17. Angelica sinensis suppresses human lung adenocarcinoma A549 cell metastasis by regulating MMPs/TIMPs and TGF-β1
18. Angelica sinensis (also called danggui in Chinese) is one of the most commonly used traditional herbs in China. It is recommended as a tonic, hemopoetic, spasmolytic, and analgesic drug in clinical practice [4]. In our previous study, n-butylidenephthalide (BP), a compound isolated from Angelica sinensis chloroform extract, exhibits growth inhibitory activity on various human cancer cell lines, including brain, lung and liver cancer cells.
19. Inhibitory effect of Angelica sinensis extract in the presence of 2-hydroxypropyl-β-cyclodextrin
20. Oral administration of Angelica sinensis polysaccharide protects against pancreatic islets failure in type 2 diabetic mice: Pancreatic β-cell apoptosis inhibition
21. [colorectal cancer preventive effect of combined administration of phenolic acids and supercritical extracts from Angelica sinensis].
22. Senescence Effects of Angelica sinensis Polysaccharides on Human Acute Myelogenous leukemia Stem and Progenitor Cells
23. Angelica sinensis polysaccharide induces erythroid differentiation of human chronic myelogenous leukemia k562 cells.
24. [Experimental study on aging effect of Angelica sinensis polysaccharides combined with cytarabine on human leukemia KG1alpha cell lines].
25. Structure characterization and anti-leukemia activity of a novel polysaccharide from Angelica sinensis (Oliv.) Diels
26. [Biological mechanisms of human-derived leukemia stem cells senescence regulated by Angelica sinensis polysaccharide].
27. Effects of combined injection of Angelica sinensis polysaccharide and cytarabine on bone marrow mononuclear cells of transplanted human leukemia mice
28. Angelica sinensis polysaccharide nanoparticles as a targeted drug delivery system for enhanced therapy of liver cancer
29. Angelica sinensis: A Chinese herb for brain cancer therapy
30. A novel polysaccharide, isolated from Angelica sinensis (Oliv.) Diels induces the apoptosis of cervical cancer HeLa cells through an intrinsic apoptotic pathway
31. Anti-Cancer Effect of Angelica Sinensis on Women’s Reproductive Cancer
32. Natural Products Reported as Potential Inhibitorsof Uterine Cervical Neoplasia
33. The effects of polysaccharides from the root of Angelica sinensis on tumor growth and iron metabolism in H22-bearing mice
34. Angelica sinensis: A Chinese herb for brain cancer therapy
35. The anticancer effects of ferulic acid is associated with induction of cell cycle arrest and autophagy in cervical cancer cells
36. Medical composition for inhibiting the growth of cancer stem cells

antroquinonol

1. Antroquinonol blocks Ras and Rho signaling via the inhibition of protein isoprenyltransferase activity in cancer cells

Bilberry extract Anthocyanin

1. Effects of commercial anthocyanin-rich extracts on colonic cancer and nontumorigenic colonic cell growth
2. Anthocyanin-rich extracts inhibit multiple biomarkers of colon cancer in rats
3. Antitumor effect of anthocyanin fractions extracted from red soybeans and red beans in vitro and in vivo
4. Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula
5. Structure− function relationships of anthocyanins from various anthocyanin-rich extracts on the inhibition of colon cancer cell growth
6. Anticancer activities of an anthocyanin-rich extract from black rice against breast cancer cells in vitro and in vivo
7. Antitumor effect of hydrolyzed anthocyanin from grape rinds and red rice
8. Anthocyanin fraction from potato extracts is cytotoxic to prostate cancer cells through activation of caspase-dependent and caspase-independent pathways
9. Anthocyanins and their role in cancer prevention
10. Cranberry and blueberry: evidence for protective effects against cancer and vascular diseases
11. Anthocyanin Extracted from Black Soybean Reduces Prostate Weight and Promotes Apoptosis in the Prostatic Hyperplasia-Induced Rat Model
12. Anthocyanins: Targeting of Signaling Networks in Cancer Cells
13. Anthocyanin Induces Apoptosis of DU-145 Cells In Vitro and Inhibits Xenograft Growth of Prostate Cancer
14. Autophagy inhibition enhances anthocyanin-induced apoptosis in hepatocellular carcinoma
15. Evaluation of Antiproliferative Activity of Red Sorghum Bran Anthocyanin on a Human Breast Cancer Cell Line (MCF-7)
16. Cytotoxic Effects of Bilberry Extract on MCF7-GFP-Tubulin Breast Cancer Cells
17. Isolation of bioactive constituents from Vaccinium myrtillus (bilberry) fruits and cell cultures β-Sitosterol and the carotenoids lutein and zeaxanthin were identified as components of the active hexane extract, which also exhibited a growth suppressing effect against two human breast cancer cell lines MCF-7 and BT-20.
18. [Dietary supplementation with bilberry extract prevents macular degeneration and cataracts in senesce-accelerated OXYS rats].
19. Protective effect of anthocyanin-rich extract from bilberry (Vaccinium myrtillus L.) against myelotoxicity induced by 5-fluorouracil
20. Anthocyanins extract from bilberry enhances the therapeutic effect of pollen of Brassica napus L. on stress-provoked benign prostatic hyperplasia in restrained mice
21. Antioxidative efficiency of an anthocyanin rich bilberry extract in the human colon tumor cell lines Caco-2 and HT-29
22. Inhibition of pancreatic cancer cell migration by plasma anthocyanins isolated from healthy volunteers receiving an anthocyanin-rich berry juice
23. Abstract 1615: Anthocyanin-rich black raspberry extract negatively regulates stem cell related molecules, EMT, and pluripotency of pancreatic cancer stem cells
24. Anthocyanin from Mulberry Extract Protects Hyperglycemia-Induced Pancreatic β-cell Apoptosis
25. Bilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway
26. Anthocyanin-rich bilberry extract induces apoptosis in acute lymphoblastic leukemia cells via redox-sensitive epigenetic modifications
27. Evaluation of anthocyanin levels after consumption of bilberry extract in patients with colorectal cancer and liver metastases
28. Influence of bilberry-derived anthocyanidins on key regulators of colorectal cancer development.
29. Prevention and treatment of familial adenomatous polyposis and colorectal cancer by bilberry-derived anthocyanidins.
30. Antiproliferative and Antioxidant Properties of Anthocyanin Rich Extracts from Blueberry and Blackcurrant Juice
31. Antioxidant Activities of Chokeberry Extracts and the Cytotoxic Action of Their Anthocyanin Fraction on HeLa Human Cervical Tumor Cells
32. Anticarcinogenic Activity of Strawberry, Blueberry, and Raspberry Extracts to Breast and Cervical Cancer Cells
33. Berry Extracts Exert Different Antiproliferative Effects against Cervical and Colon Cancer Cells Grown in Vitro
34. Beyond Conventional Medicine – a Look at Blueberry, a Cancer-Fighting Superfruit
35. Blueberry as a Potential Radiosensitizer for Treating Cervical Cancer
36. Health benefits of anthocyanins and molecular mechanisms: Update from recent decade
37. Cancer prevention with freeze-dried berries and berry components
38. Anthocyanins and Cancer Prevention
39. The studies of cyanidin 3-glucoside-induced apoptosis in human cervical cancer Hela cells and its mechanism

Antrodia cinnamomea

1. Antrodia cinnamomea fruiting bodies extract suppresses the invasive potential of human liver cancer
2. Antitumor effects of the partially purified polysaccharides from Antrodia camphorata and the mechanism of its action
3. Anti-angiogenic effects and mechanisms of polysaccharides from Antrodia cinnamomea with different molecular weights
4. Study for anti-angiogenic activities of polysaccharides isolated from Antrodia cinnamomea in endothelial cells
5. Review of pharmacological effects of Antrodia camphorata and its bioactive compounds
6. Anti-inflammatory effects of methanol extract of Antrodia cinnamomea mycelia both in vitro and in vivo
7. Apoptotic effects of extract from Antrodia camphorata fruiting bodies in human hepatocellular carcinoma cell lines
8. Antioxidant Properties of Antrodia camphorata in Submerged Culture
9. Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells
10. Growth inhibition and induction of apoptosis in MCF-7 breast cancer cells by Antrodia camphorata
11. Inhibition of growth, migration and invasion of human bladder cancer cells by antrocin, a sesquiterpene lactone isolated from Antrodia cinnamomea, and its molecular
12. Ethanol Extracts of Fruiting Bodies of Antrodia cinnamomea Suppress CL1-5 Human Lung Adenocarcinoma Cells Migration by Inhibiting Matrix Metalloproteinase-2/9 through ERK, JNK, p38, and PI3K/Akt Signaling Pathways
13. Ethanol extracts of fruiting bodies of Antrodia cinnamomea exhibit anti-migration action in human adenocarcinoma CL1-0 cells through the MAPK and PI3K/AKT signaling pathways
14. Unique Formosan Mushroom Antrodia camphorata Differentially Inhibits Androgen-Responsive LNCaP and -Independent PC-3 Prostate Cancer Cells
15. Antrodan, A β-glucan obtained from Antrodia cinnamomea mycelia, is beneficial to benign prostate hyperplasia
16. Elucidating the inhibitory mechanisms of the ethanolic extract of the fruiting body of the mushroom Antrodia cinnamomea on the proliferation and migration of murine leukemia WEHI-3 cells and their tumorigenicity in a BALB/c allograft tumor model
17. Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells
18. Growth inhibition and induction of apoptosis in MCF-7 breast cancer cells by Antrodia camphorata
19. Novel effect and the mechanistic insights of fruiting body extract of medicinal fungus Antrodia cinnamomea against T47D breast cancer
20. Inhibition of cyclooxygenase-2 and induction of apoptosis in estrogen-nonresponsive breast cancer cells by Antrodia camphorata
21. Identification of Antrocin from Antrodia camphorata as a Selective and Novel Class of Small Molecule Inhibitor of Akt/mTOR Signaling in Metastatic Breast Cancer MDA-MB-231 Cells
22. Anticancer effects on human pancreatic cancer cells of triterpenoids, polysaccharides and 1,3-β-d-glucan derived from the fruiting body of Antrodia camphorata†
23. Inhibition of the survival of pancreatic cancer by cyclohexenone compounds from Antrodia camphorata
24. Antrodia cinnamomea induces autophagic cell death via the CHOP/TRB3/Akt/mTOR pathway in colorectal cancer cells
25. Molecular mechanism of Antrodia cinnamomea sulfated polysaccharide on the suppression of lung cancer cell growth and migration via induction of transforming growth factor β receptor degradation
26. Coenzyme Q0 from Antrodia cinnamomea in Submerged Cultures Induces Reactive Oxygen Species-Mediated Apoptosis in A549 Human lung cancer Cells
27. Antrodia cinnamomea induces anti-tumor activity by inhibiting the STAT3 signaling pathway in lung cancer cells
28. Suppression of Cell Growth, Migration and Drug Resistance by Ethanolic Extract of Antrodia cinnamomea in Human lung cancer A549 Cells and C57BL/6J Allograft Tumor Model
29. Antrodia Cinnamomea Prolongs Survival in a Patient with Small Cell lung cancer
30. Method of preparing bioactive compound from solid-state cultivated Antrodia cinnamomea mycelium for anti-metastasis against lung cancer cells
31. A sulfated glucan from Antrodia cinnamomea reduces Slug expression through regulation of TGFβ/AKT/GSK3β axis in lung cancer
32. 4-Acetylantroquinonol B from antrodia cinnamomea enhances immune function of dendritic cells against liver cancer stem cells
33. Antrodia cinnamomea fruiting bodies extract suppresses the invasive potential of human liver cancer cell line PLC/PRF/5 through inhibition of nuclear factor κB pathway.
34. Cytotoxic Effect and Induction of Apoptosis in Human Cervical Cancer Cells by Antrodia camphorata
35. Pinicolol B from Antrodia cinnamomea induces apoptosis of nasopharyngeal carcinoma cells
36. A polysaccharide from Antrodia cinnamomea mycelia exerts antitumor activity through blocking of TOP1/TDP1-mediated DNA repair pathway

Artemisinin Artemisia annua L. (Huanghuahao)

1. Flavonoids from Artemisia annua L. as antioxidants and their potential synergism with artemisinin against malaria and cancer
2. Antiproliferative effects of extracts from Iranian Artemisia species on cancer cell lines
3. Inhibitory effect of jaceosidin isolated from Artemisia argyi on the function of E6 and E7 oncoproteins of HPV 16
4. Eupatilin, a Pharmacologically Active Flavone Derived from Artemisia Plants, Induces Apoptosis in Human Gastric Cancer (AGS) Cells
5. Composition and anti-oxidant, anti-cancer and anti-inflammatory activities of Artemisia herba-alba, Ruta chalpensis L. and Peganum harmala L.
6. Anti-inflammatory and immunosuppressive effect of flavones isolated from Artemisia vestita
7. Study ontoxic effects of Artemisisa spp. fractions from Iran on human cancer cell lines
8. Effects of artemisinin and its derivatives on growth inhibition and apoptosis of oral cancer cells
9. Artemisia princeps var orientalis induces apoptosis in human breast cancer MCF-7 cells
10. Oral artemisinin prevents and delays the development of 7, 12-dimethylbenz [a] anthracene (DMBA)-induced breast cancer in the rat
11. Synthetic Derivatives of Artemisinin and Cancer
12. Ethnopharmacology of Artemisia annua L.: A Review Research studies also report that artemisinin is effective for killing human breast cancer cells.
13. Artemisia Species in Small Ruminant Production: their PotentialAntioxidant and Anthelmintic Effects.
14. Nanocarriers for Delivery of Herbal Based Drugs in Breast Cancer – An Overview
15. An Overview of the Current Development of Phytoremedies for Breast Cancer
16. Role of angiogenic factors of herbal origin in regulation of molecular pathways that control tumor angiogenesis
17. Antitumor activity of an Artemisia annua herbal preparation and identification of active ingredients
18. Evaluation of the anticancer activities of pomegranate (Punica granatum) and harmal (Rhazya stricta) plants grown in Saudi arabia
19. Artemisinin as a Chinese medicine, selectively induces apoptosis in pancreatic tumor cell line
20. Potent anticancer activity of the second generation artemisinin-derived trioxane dimers on pancreatic cancer cells.
21. Preclinical Efficacy and Safety Assessment of Artemisinin-Chemotherapeutic Agent Conjugates for ovarian cancer
22. Artemisinin derivatives inhibit epithelial ovarian cancer cells via autophagy-mediated cell cycle arrest
23. Abstract 470: Artemisinin derivatives synergize with paclitaxel by targeting FOXM1 through Raf/MEK/MAPK signaling pathway in ovarian cancer
24. Artemisinin induced reversal of EMT affects the molecular biological activity of ovarian cancer SKOV3 cell lines
25. Artemisinin inhibits the proliferation, migration, and inflammatory reaction induced by tumor necrosis factor-α in vascular smooth muscle cells through nuclear factor kappa B pathway
26. Artemisinin derivative artesunate induces radiosensitivity in cervical cancer cells in vitro and in vivo
27. Use of artemisinin and its derivatives to treat HPV-infected/transformed cells and cervical cancer: a review
28. Selective Radiosensitization of Human Cervical Cancer Cells and Normal Cells by Artemisinin Through the Abrogation of Radiation-Induced G2 Block
29. Study on the radiosensitizing effect of artemisinin on human cervical cancer and corresponding mechanisms.
30. Synthesis of Artemisinin–Estrogen Hybrids Highly Active against HCMV, P. falciparum, and Cervical and Breast Cancer
31. Molecular alterations induced by artemisinin in HPV-39 infected human cervical cancer cells
32. Artemisinin derivative artesunate induces radiosensitivity in cervical cancer cells in vitro and in vivo

Artepillin C (Brazilian propolis)

1. Apoptosis and suppression of tumor growth by artepillin C extracted from Brazilian propolis.
2. Suppression of tumor-induced angiogenesis by Brazilian propolis: major component artepillin C inhibits in vitro tube formation and endothelial cell proliferation
3. Anti-inflammatory effects of a bioavailable compound, Artepillin C, in Brazilian propolis
4. Apoptosis of human leukemia cells induced by Artepillin C, an active ingredient of Brazilian propolis.
5. Pulmonary carcinogenesis induced by ferric nitrilotriacetate in mice and protection from it by Brazilian propolis and artepillin C
6. Artepillin C (3, 5-diprenyl-4-hydroxycinnamic acid) sensitizes LNCaP prostate cancer cells to TRAIL-induced apoptosis
7. Artepillin C in Brazilian propolis induces G0/G1 arrest via stimulation of Cip1/p21 expression in human colon cancer cells
8. Renal carcinogenesis induced by ferric nitrilotriacetate in mice, and protection from it by Brazilian propolis and artepillin C
9. Antioxidative bioavailability of artepillin C in Brazilian propolis
10. Cell growth inhibitory effect of cinnamic acid derivatives from propolis on human tumor cell lines
11. Artepillin C induces selective oxidative stress and inhibits migration and invasion in a comprehensive panel of human cervical cancer cell lines.
12. Ethanolic extract of Brazilian green propolis sensitizes prostate cancer cells to TRAIL-induced apoptosis
13. Artepillin C (ARC) in Brazilian green propolis selectively blocks oncogenic PAK1 signaling and suppresses the growth of NF tumors in mice
14. Antiproliferation of human prostate cancer cells by ethanolic extracts of Brazilian propolis and its botanical origin
15. Inhibition of Inflammatory Response by Artepillin C in Activated RAW264.7 Macrophages
16. Ivermectin inactivates the kinase PAK1 artepillin C (ARC), the major anti-cancer ingredients in propolis,and blocks the PAK1-dependent growth of human ovarian cancer and NF2 tumor cell lines
17. Preferential cytotoxicity to tumor cells of 3,5-diprenyl-4-hydroxycinnamic acid (artepillin C) isolated from propolis.
18. Antiproliferative Activity of Brown Cuban Propolis Extract on Human Breast Cancer Cells
19. Biological Therapy Using Propolis as Nutritional Supplement in Cancer Treatment It was observed that administration of paclitaxel and propolis effectively suppressed breast cancer
20. Brazilian green propolis and its constituent, Artepillin C inhibits allogeneic activated human CD4 T cells expansion and activation
21. Propolis in Dentistry and Oral Cancer Management CAPE is a well-known NF-κB inhibitor at high concentrations of 50-80 μM. CAPE treatment suppresses the proliferation of several human cancer cell lines, including breast, prostate, lung, cervical, and oral cancer cells.
22. Apoptosis of human leukemia cells induced by Artepillin C, an active ingredient of Brazilian propolis.
23. Apoptosis of human leukemia cell lines induced by Artepillin C extracted from Brazilian propolis
24. Artepillin C in Brazilian propolis induces G0/G1 arrest via stimulation of Cip1/p21 expression in human colon cancer cells
25. Evaluate the cytotoxic activity of honey, propolis, and bee venom from different localities in Egypt against liver, breast, and colorectal cancer
26. Artepillin C induces selective oxidative stress and inhibits migration and invasion in a comprehensive panel of human cervical cancer cell lines

Ashwagandha

1. Effect of Withania somnifera (Ashwagandha) on the Development of Chemotherapy-Induced Fatigue and Quality of Life in Breast Cancer Patients
2. Genomic analysis highlights the role of the JAK-STAT signaling in the anti-proliferative effects of dietary flavonoid—’Ashwagandha’in prostate cancer cells
3. Withania somnifera Dunal (Ashwagandha): potential plant source of a promising drug for cancer chemotherapy and radiosensitization.
4. Selective killing of cancer cells by leaf extract of Ashwagandha: Components, activity and pathway analyses
5. Selective killing of cancer cells by Ashwagandha leaf extract and its component Withanone involves ROS signaling
6. Antitumor and radiosensitizing effects of Withania somnifera (Ashwagandha) on a transplantable mouse tumor, Sarcoma-180.
7. Ashwagandha (Withania somnifera): Role in safeguarding health, immunomodulatory effects, combating infections and therapeutic applications: A review
8. In vivo growth inhibitory effect of Withania somnifera (Ashwagandha) on a transplantable mouse tumor, Sarcoma 180.
9. Protective role of Ashwagandha leaf extract and its component withanone on scopolamine-induced changes in the brain and brain-derived cells
10. Water extract of ashwagandha leaves limits proliferation and migration, and induces differentiation in glioma cells
11. Ashwagandha for Cancer Metastasis: Bioactives and Basics of Their Function
12. VARIAN TUMOR-ASSOCIATED GRP78 INDUCES IMMUNOSUPPRESSION AND WITHAFERIN A (ASHWAGANDHA) ENHANCES ANTI-TUMOR
13. Effect of Withania somnifera (Ashwagandha) on the Development of Chemotherapy-Induced Fatigue and Quality of Life in Breast Cancer Patients
14. Selective Killing of Cancer Cells by Ashwagandha Leaf Extract and Its Component Withanone Involves ROS Signaling
15. Selective cytotoxicity of non-small cell lung cancer cells by the withaferin A-fortified root extract of Ashwagandha involves differential cell-cycle arrest and apoptosis APE is a well-known NF-κB inhibitor at high concentrations of 50-80 μM. CAPE treatment suppresses the proliferation of several human cancer cell lines, including breast, prostate, lung, cervical, and oral cancer cells.
16. AOS14 Phase II clinical study of combination chemotherapy with herb Withania somnifera (ashwagandha) in breast cancer
17. Withaferin A inhibits breast cancer invasion and metastasis at sub‐cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation
18. Ashwagandha Derived Withanone Targets TPX2-Aurora A Complex: Computational and Experimental Evidence to its Anticancer Activity
19. Dietary Supplementation of Ashwagandha (Withania somnifera, Dunal) Enhances NK Cell Function in Ovarian Tumors in the Laying Hen Model of Spontaneous ovarian cancer
20. Prevention of ovarian cancer metastasis by dietary Ashwagandha supplementation
21. Abstract B061: Association of leukocyte inhibitory immunoglobulin-like transcript 3 (ILT3) with ovarian cancer and prevention of its expression by dietary supplementation of Ashwagandha (Withania somnifera)
22. Dietary supplementation of Ashwagandha (W. somnifera, Dunal) enhances NK cell function against ovarian tumors in laying hen model of spontaneous ovarian cancer: P-8

Astragalus membranaceus extract

1. In vitro and in vivo anti-tumor effects of Astragalus membranaceus
2. In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceus
3. Suppressive effect of Astragalus membranaceus Bunge on chemical hepatocarcinogenesis in rats
4. Antitumor and immunomodulatory activity of Astragalus membranaceus polysaccharides in H22 tumor-bearing mice
5. A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb
6. Effects of cycloartane saponins from hairy roots of Astragalus membranaceus Bge., on human tumor cell targets
7. Macrophage activation by polysaccharide isolated from Astragalus membranaceus
8. Immune system effects of echinacea, ginseng, and astragalus: a review
9. Differential effects of isoflavones, from Astragalus membranaceus and Pueraria thomsonii, on the activation of PPARα, PPARγ, and adipocyte differentiation in vitro
10. Effects of components isolated from Astragalus membranaceus Bunge on cardiac function injured by myocardial ischemia reperfusion in rats
11. Astragalus membranaceus: A Review of its Protection Against Inflammation and Gastrointestinal Cancers
12. Astragalus membranaceus: A review study of its anti-carcinoma activities
13. Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells
14. Does Astragalus Membranaceus Root Extract Have Any Survival Benefit for Metastatic Non-Small Cell Lung Cancer?
15. Inhibition of Astragalus membranaceuspolysaccharides against liver cancer cell HepG2
16. Accumulating evidences demonstrated the anticancer activity of formononetin on breast cancer
17. We showed that formononetin inhibited the phosphorylation of AKT and induced the apoptosis of CC cell line HeLa in a dose-dependent manner.
18. Effects of herbal preparation Equiguard™ on hormone-responsive and hormone-refractory prostate carcinoma cells: Mechanistic studies hese studies used prostate cancer cells mimicking the androgen-dependent (AD) and androgen-independent (AI) states of prostate carcinogenesis.
19. Astragaloside IV Enhances Cisplatin Chemosensitivity in Non-Small Cell lung cancer Cells Through Inhibition of B7-H3
20. Immunotherapy with Chinese medicinal herbs. I. Immune restoration of local xenogeneic graft-versus-host reaction in cancer patients by fractionated Astragalus membranaceus in vitro.
21. Astragalus membranaceus lectin (AML) induces caspase‐dependent apoptosis in human leukemia cells
22. Herbal Extract SH003 Suppresses Tumor Growth and Metastasis of MDA-MB-231 Breast Cancer Cells by Inhibiting STAT3-IL-6 Signaling
23. Astragaloside IV inhibits breast cancer cell invasion by suppressing Vav3 mediated Rac1/MAPK signaling
24. Biochanin A Promotes Proliferation that Involves a Feedback Loop of MicroRNA-375 and Estrogen Receptor Alpha in Breast Cancer Cells O-methylated isoflavones that are isolated from the root of Astragalus membranaceus, and have antitumorigenic effects.
25. Astragalus membranaceus lectin (AML) induces caspase‐dependent apoptosis in human leukemia cells
26. [Effects of large dose of Astragalus membranaceus on the dendritic cell induction of peripheral mononuclear cell and antigen presenting ability of dendritic cells in children with acute leukemia].
27. Induction of Apoptosis by Ethyl Acetate Fraction of Astragalus membranaceus in Human Non-small Cell lung cancer Cells
28. Changes of platelet Parameter in Patients with lung cancer Treated by Chemotherapy and Effects of Astragalus Membranaceus Injection
29. Study of the anticarcinogenic mechanisms of astragalus membranaceus in colon cancer cells and tumor xenograft
30. The antitumorigenic potential of total saponins from radix Astragalus membranaceus as chemotherapeutic adjuvant in treating colon cancer
31. An in vivo molecular response analysis of colorectal cancer treated with Astragalus membranaceus extract
32. [Effects of Couplet Medicines (Astragalus Membranaceus and Jiaozhen) on Intestinal Barrier in Postoperative colorectal cancer Patients].
33. Inhibitory effect of Astragalus membranaceus root on matrix metalloproteinase‐1 collagenase expression and procollagen destruction in ultraviolet B‐irradiated human dermal fibroblasts by suppressing nuclear factor kappa‐B activity
34. Astragalus membranaceus and Salvia miltiorrhiza Ameliorate Lipopolysaccharide-Induced Acute Lung Injury in Rats by Regulating the Toll-Like Receptor 4/Nuclear Factor-Kappa B Signaling Pathway
35. [Astragalus polysaccharide may increase sensitivity of cervical cancer HeLa cells to cisplatin by regulating cell autophagy].
36. [Regulatory effect of astragalus injection on Th1/Th2 cell function in patients with cervical cancer].

Belamcanda chinensis

1. Phytoestrogens derived from Belamcanda chinensis have an antiproliferative effect on prostate cancer cells in vitro
2. Other phytochemicals extracted from leopard lily Belamcanda chinensis affect new and established targets for therapies in prostate cancer
3. Phytoestrogens from Belamcanda chinensis regulate the expression of steroid receptors and related cofactors in LNCaP prostate cancer cells
4. Phenolic Constituents of the Rhizomes of the Thai Medicinal Plant Belamcanda chinensis with Proliferative Activity for Two Breast Cancer Cell Lines
5. Chemical constituents of the ethyl acetate extract of Belamcanda chinensis (L.) DC roots and their antitumor activities
6. Antimutagenic and anti-oxidant activities of isoflavonoids from Belamcanda chinensis (L.) DC
7. Hypoglycemic effect of Belamcanda chinensis leaf extract in normal and STZ-induced diabetic rats and its potential active faction
8. Inhibitory effects of Irigenin from the rhizomes of Belamcanda chinensis on nitric oxide and prostaglandin E2 production in murine macrophage RAW 264.7 cells
9. Advances in research on phytochemical constituents and pharmacology of Belamcanda chinensis [J]
10. Iristectorigenin B isolated from Belamcanda chinensis is a liver X receptor modulator that increases ABCA1 and ABCG1 expression in macrophage RAW 264.7 cells
11. Phytoestrogens derived from Belamcanda chinensis have an antiproliferative effect on prostate cancer cells in vitro.
12. Phytoestrogens from Belamcanda chinensis regulate the expression of steroid receptors and related cofactors in LNCaP prostate cancer cells.
13. PHYTOESTROGENS DERIVED FROM BELAMCANDA CHINENSIS HAVE AN ANTIPROLIFERATIVE EFFECT ON PROSTATE CANCER CELLS IN VITRO
14. Phytoestrogens from Belamcanda chinensis regulate the expression of steroid receptors and related cofactors in LNCaP prostate cancer cells.
16. Belamcanda chinensis and the thereof purified tectorigenin have selective estrogen receptor modulator activities
17. PHYTOESTROGENS DERIVED FROM BELAMCANDA CHINENSIS HAVE AN ANTIPROLIFERATIVE EFFECT ON PROSTATE CANCER CELLS IN VITRO
18. In vitro antitumor and antioxidant activities of Belamcanda chinensis (L.) DC
19. Phytoestrogens from Belamcanda chinensis regulate the expression of steroid receptors and related cofactors in LNCaP prostate cancer cells
20. [Pharmacological potential of phytoestrogens in the treatment of prostate cancer].Phytooestrogenes interact with these mechanisms as demonstrated exemplarily in the presented study with the isoflavone tectorigenin derived from Belamcanda chinensis.

Berberine (Cortidis rhizoma)

1. Inhibitory effect of Coptidis Rhizoma and berberine on the proliferation of human esophageal cancer cell lines
2. Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells
3. Inhibitory effect of berberine on the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2
4. Modulation of apoptosis by berberine through inhibition of cyclooxygenase-2 and Mcl-1 expression in oral cancer cells
5. The combination of berberine and irradiation enhances anti‐cancer effects via activation of p38 MAPK pathway and ROS generation in human hepatoma cells
6. Effect of berberine on the antioxidant status, ultrastructural modifications and protein bound carbohydrates in azoxymethane-induced colon cancer in rats
7. Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells
8. The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest
9. Berberine modulates expression of mdr1 gene product and the responses of digestive track cancer cells to Paclitaxel
10. Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells
11. Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation
12. Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells
13. Berberine inhibits p53-dependent cell growth through induction of apoptosis of prostate cancer cells
14. Berberine Suppresses Androgen Receptor Signaling in Prostate Cancer
15. Berberine, a genotoxic alkaloid, induces ATM-Chk1 mediated G2 arrest in prostate cancer cells
16. Berberine induces apoptosis in breast cancer cells (MCF-7) through mitochondrial-dependent pathway
17. Berberine Suppresses TNF-α-induced MMP-9 and Cell Invasion through Inhibition of AP-1 Activity in MDA-MB-231 Human Breast Cancer Cells
18. Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer
19. Modulation of drug-resistant membrane and apoptosis proteins of breast cancer stem cells by targeting berberine liposomes
20. Berberine Inhibits Growth of the Breast Cancer Cell Lines MCF-7 and MDA-MB-231
21. Berberine Inhibits Cell Growth and Mediates Caspase-Independent Cell Death in Human pancreatic cancer Cells
22. Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in pancreatic cancer Cells
23. Berberine diminishes side population and down-regulates stem cell-associated genes in the pancreatic cancer cell lines PANC-1 and MIA PaCa-2
24. Abilities of berberine and chemically modified berberines to inhibit proliferation of pancreatic cancer cells
25. Tu1889 The Isoquinoline Alkaloid Berberine Inhibits the Growth of Human pancreatic cancer Cells In Vitro and In Vivo
26. Genome-scale microRNA identify small RNA modulators of the effect of berberine on pancreatic cancer cell growth
27. Abilities of berberine and chemically modified berberines to interact with metformin and inhibit proliferation of pancreatic cancer cells
28. Tu1916 Berberine Potently Activates AMPK and Inhibits mTORC1, ERK and Cell Cycle Progression of Human pancreatic cancer Cells In Vitro and Reduces the Growth of Human pancreatic cancer Xenografts In Vivo
29. Tu2034 Berberine Inhibits the Growth of Human pancreatic cancer Cells In Vitro and In Vivo
30. Tu1988 Role of AMPK in the Inhibitory Effects of Metformin and Berberine on mTORC1, ERK, DNA Synthesis and Proliferation in Human pancreatic cancer Cells
31. Apoptosis of Human leukemia HL-60 Cells and Murine leukemia WEHI-3 Cells Induced by Berberine through the Activation of Caspase-3
32. Berberine‐induced apoptosis of human leukemia HL‐60 cells is associated with down‐regulation of nucleophosmin/B23 and telomerase activity
33. Down-regulation of Cyclin B1 and Up-regulation of Wee1 by Berberine Promotes Entry of leukemia Cells into the G2/M-phase of the Cell Cycle
34. Berberine Inhibits WEHI-3 leukemia Cells In Vivo
35. Effects of Berberine on Arylamine N-acetyltransferase Activity and 2-Aminofluorene-DNA Adduct Formation in Human leukemia Cells
36. Berberine inhibits arylamine N-acetyltransferase activity and gene expression in mouse leukemia L 1210 cells
37. Berberine Decreased N-acetylation of 2-Aminofluorene through Inhibition of N-acetyltransferase Gene Expression in Human leukemia HL-60 Cells
38. Berberine Induces Apoptosis in p53-Null leukemia Cells by Down-Regulating XIAP at the Post-Transcriptional Level
39. Berberine Induces Apoptotic Cell Death via Activation of Caspase-3 and -8 in HL-60 Human leukemia Cells: Nuclear Localization and Structure–Activity Relationships
40. Synergistic Effect of TPD7 and Berberine against leukemia Jurkat Cell Growth through Regulating Ephrin‐B2 Signaling
41. The natural alkaloid berberine targets multiple pathways to induce cell death in cultured human colon cancer cells
42. Berberine inhibits the proliferation of colon cancer cells by inactivating Wnt/β-catenin signaling
43. Berberine inhibits human colon cancer cell migration via AMP-activated protein kinase-mediated downregulation of integrin β1 signaling
44. Berberine enhances chemosensitivity to irinotecan in colon cancer via inhibition of NF‑κB
45. Multiple Effects of Berberine Derivatives on colon cancer Cells
46. Effect of new berberine derivatives on colon cancer cells
47. Mechanisms involved in the cytotoxic effects of berberine onhuman colon cancer HCT-8 cells
48. Berberine binds RXRα to suppress β-catenin signaling in colon cancer cells
49. Fluorescent organic ion pairs based on berberine: counter-ion effect on the formation of particles and on the uptake by colon cancer cells
50. [Preventive effects of berberine on experimental colon cancer and relationship with cyclooxygenase-2 expression].
51. Berberine, a natural isoquinoline alkaloid, induces NAG-1 and ATF3 expression in human colorectal cancer cells
52. Berberine Inhibits Invasion and Metastasis of colorectal cancer Cells via COX-2/PGE2 Mediated JAK2/STAT3 Signaling Pathway
53. Targeting of multiple oncogenic signaling pathways by Hsp90 inhibitor alone or in combination with berberine for treatment of colorectal cancer
54. Effect of evodiamine and berberine on miR-429 as an oncogene in human colorectal cancer
55. [Effect and mechanism of EGFR expression in macrophages on the anti-cancer effect of berberine on colorectal cancer].
56. Effects of evodiamine and berberine hydrochloride on cell apoptosis and expression of hTERT-mRNA of human colorectal cancer cell line HT-29
57. Effects of Evodiamine and Berberine Hydrochloride on Telomerase Activity of Human colorectal cancer Cell Line HT29
58. Long non‑coding RNA CASC2 enhances berberine‑induced cytotoxicity in colorectal cancer cells by silencing BCL2
59. Berberine Promotes Apoptosis of colorectal cancer via Regulation of the Long Non-Coding RNA (lncRNA) Cancer Susceptibility Candidate 2 (CASC2)/AU-Binding Factor 1 (AUF1)/B-Cell CLL/Lymphoma 2 (Bcl-2) Axis
60. Synergistic Tumor-Killing Effect of Radiation and Berberine Combined Treatment in lung cancer: The Contribution of Autophagic Cell Death
61. p53 cooperates berberine‐induced growth inhibition and apoptosis of non‐small cell human lung cancer cells in vitro and tumor xenograft growth in vivo
62. Protective effects of berberine on radiation-induced lung injury via intercellular adhesion molecular-1 and transforming growth factor-beta-1 in patients with lung cancer
63. Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells
64. Epithelial-to-mesenchymal transition markers to predict response of Berberine in suppressing lung cancer invasion and metastasis
65. Berberine Increases Doxorubicin Sensitivity by Suppressing STAT3 in lung cancer
66. Quantitative evaluation of berberine subcellular distribution and cellular accumulation in non-small cell lung cancer cells by UPLC–MS/MS
67. Effect of berberine on activity and mRNA expression of N-acetyltransferase in human lung cancer cell line A549
68. Berberine hydrochloride inhibits cell proliferation and promotes apoptosis of non-small cell lung cancer via the suppression of the MMP2 and Bcl-2/Bax signaling pathways
69. Synergistic tumor-killing effect of radiation and berberine combined treatment in lung cancer
70. Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: The cellular mechanism†
71. Berberine induces apoptosis via the mitochondrial pathway in liver cancer cells
72. Investigation of differentially expressed proteins due to the inhibitory effects of berberine in human liver cancer cell line HepG2
73. Functional Cross-Talking between Differentially Expressed and Alternatively Spliced Genes in Human liver cancer Cells Treated with Berberine
74. Berberine, a natural plant alkaloid, synergistically sensitizes human liver cancer cells to sorafenib
75. Cancer cell membrane-modified biodegradable mesoporous silica nanocarriers for berberine therapy of liver cancer
76. Gram‐scale production of carrier‐free fluorescent berberine microrods for selective liver cancer therapy
77. Berberine-loaded Janus gold mesoporous silica nanocarriers for chemo/radio/photothermal therapy of liver cancer and radiation-induced injury inhibition
78. Sensitizing Effect of Berberine on Radiation-Induced Cytotoxicity in Human liver cancer Cells
79. Berberine Sensitizes Human ovarian cancer Cells to Cisplatin Through miR-93/PTEN/Akt Signaling Pathway
80. Berberine sensitizes ovarian cancer cells to cisplatin through miR-21/PDCD4 axis
81. Berberine Exhibits Antitumor Effects in Human ovarian cancer Cells
82. Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells
83. Berberine induces oxidative DNA damage and impairs homologous recombination repair in ovarian cancer cells to confer increased sensitivity to PARP inhibition
84. Berberine inhibits the chemotherapy‐induced repopulation by suppressing the arachidonic acid metabolic pathway and phosphorylation of FAK in ovarian cancer
85. Research of berberine to proliferation and apoptotic mechanism of human ovarian cancer cell line SKOV3
86. Effects of berberine on proliferation and apoptosis of human ovarian cancer cell line SKOV-3 in vitro
87. Effect of berberine on D-dimer, fibrinogen and interleukin-6 in peripheral blood of ovarian cancer patients
88. Berberine in combination with cisplatin induces necroptosis and apoptosis in ovarian cancer cells
89. Effects of berberine on matrix accumulation and NF-kappa B signal pathway in alloxan-induced diabetic mice with renal injury
90. Effect of Berberine on the Expression of Nuclear Factor Kappa B,Vascular Cell Adhesion Molecule-1 and Monocyte Chemoattractant Protein-1 in Carotid Artery Atherosclerosis of Rabbits
91. Effects of 13-hexyl-berberine hydrochloride and 13-hexyl-palmatine hydrochloride on the activation of nuclear factor-kappa B and phosphorylation of p38 mitogen-activated kinase (MAPK) in a human keratinocyte cell line, HaCaT stimulated by tumor necrosis factor alpha.
92. Berberine Inhibited the Growth of Thyroid Cancer Cell Lines 8505C and TPC1
93. Delayed luminescence to monitor programmed cell death induced by berberine on thyroid cancer cells
94. [The effects and mechanisms of berberine on proliferation of papillary thyroid cancer K1 cells induced by high glucose].
95. Berberine, a natural compound, suppresses Hedgehog signaling pathway activity and cancer growth
96. Molecular Modelling of Berberine Derivatives as Inhibitors of Human Smoothened Receptor and Hedgehog Signalling Pathway Using a Newly Developed Algorithm on Anti-Cancer Drugs
97. Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells
98. GADD153 Mediates Berberine-induced Apoptosis in Human Cervical Cancer Ca Ski Cells
99. Berberine Reverses Epithelial-to-Mesenchymal Transition and Inhibits Metastasis and Tumor-Induced Angiogenesis in Human Cervical Cancer Cells
100. Berberine alters epigenetic modifications, disrupts microtubule network, and modulates HPV-18 E6–E7 oncoproteins by targeting p53 in cervical cancer cell HeLa: A mechanistic study including molecular docking
101. Study on the Effect of Berberine in Human Cervical Cancer Hela Cells in Vitro
102. Effect of berberine on radiosensitivity of cervical cancer cells
103. Abstract C38: Berberine/cisplatin-based radiotherapy for cervical cancer: The new and effective method to treat cervical cancer
104. Study on the Effect of Berberine in Human Cervical Cancer Hela Cells in Vitro
105. Effects of Berberine on the Expression of Caspase-3 Gene in Human Cervical Cancer Hela Cell
106. NATURAL PLANT PRODUCT BERBERINE/CISPLATIN BASED RADIOTHERAPY FOR CERVICAL CANCER: THE NEW AND EFFECTIVE METHOD TO TREAT CERVICAL CANCER
107. Abstract A45: Berberine acts as an antagonist to estradiol-induced proliferation by inducing apoptosis in cervical cancer cells
108. Mechanism of berberine-induced apoptosis in cervical cancer HeLa cell line

Camellia sinensis

1. Epigallocatechin‐3‐gallate in camellia sinensis leaves from Himalayan region of Sikkim: Inhibitory effects against biochemical events and tumor initiation in sencar
2. Green tea (Camellia sinensis) for the prevention of cancer
3. Green tea (Camellia sinensis) extract and its possible role in the prevention of cancer
4. Inhibitory effect of six green tea catechins and caffeine on the growth of four selected human tumor cell lines.
5. Epicatechins purified from green tea (Camellia sinensis) differentially suppress growth of gender-dependent human cancer cell lines
6. Green tea (Camellia sinensis) and cancer prevention: a systematic review of randomized trials and epidemiological studies
7. Chemopreventive effect of green tea (Camellia sinensis) among cigarette smokers.
8. Chemoprotection: A review of the potential therapeutic antioxidant properties of green tea (Camellia sinensis) and certain of its constituents
9. Protective effect of green tea on the risks of chronic gastritis and stomach cancer
10. Black Tea (Camellia sinensis) as a Chemopreventive Agent in Oral Precancerous Lesions
11. Green tea (Camellia sinensis) for the prevention of cancer
12. Hepatoprotective Effect of Green Tea (Camellia sinensis) Extract against Tamoxifen-induced Liver Injury in Rats amoxifen citrate (TAM), is widely used for treatment of breast cancer.
13. The Effects of Green Tea Consumption on Incidence of Breast Cancer and Recurrence of Breast Cancer: A Systematic Review and Meta-analysis
14. (Camellia Sinensis) Extractand Its Possible Rolein the Prevention of Cancer current studies are hope-ful in suggesting a possible chemopreventiveeffect of green tea in cancer of the breast, pros-tate, and gastrointestinal tract
15. Green tea (Camellia sinensis) extract inhibits both the metastasis and osteolytic components of mammary cancer 4T1 lesions in mice
16. Nigerian foodstuffs with prostate cancer chemopreventive polyphenols
17. Active extracts of black tea (Camellia Sinensis) induce apoptosis of PC-3 prostate cancer cells via mitochondrial dysfunction
18. Plant derived products as a source of cellular growth inhibitory phytochemicals on PC-3M, DU-145 and LNCaP prostate cancer cell lines
19. The present study compared the anti-proliferative effect of black tea (Camellia sinensis) polyphenol, thearubigin (TR), alone or combined with the isoflavone genistein, on human prostate (PC-3) carcinoma cells.
20. Differential Growth Suppression of Human Melanoma Cells by Tea (Camellia sinensis) Epicatechins (ECG, EGC and EGCG)
21. Inhibitory effect of black tea (Camellia sinensis) theaflavins and thearubigins against HCT 116 colon cancer cells and HT 460 lung cancer cells
22. White tea (Camellia sinensis) inhibits proliferation of the colon cancer cell line, HT-29, activates caspases and protects DNA of normal cells against oxidative damage
23. White Tea (Camellia sinensis) Extract Role as AntiProliferative of colon cancer Cell Line,
24. Effekten av kråkbär (empetrum nigrum), extrakt från kakao (Theobroma cacao), samt ekstrakt från de två tesorterna Grönt te, Japanese Sencha (Camellia sinensis) och Rooibos (Aspalathus linearis) på proliferationen av colon cancer-cellinjen HT29
25. Flower Extract Mixture of Camellia japonica and Camellia sinensis Inhibit Cell Growth and Induces Apoptosis in HT29 Human colon cancer Cells
26. Evaluation of Anticancer Activity of Camellia Sinensis in the Caco-2 colorectal cancer Cell Line
27. Green synthesis palladium nanoparticles mediated by white tea (Camellia sinensis) extract with antioxidant, antibacterial, and antiproliferative activities toward the human leukemia (MOLT-4) cell line
28. Chemoprotective properties of rooibos (Aspalathus linearis), honeybush (Cyclopia intermedia) herbal and green and black (Camellia sinensis) teas against cancer promotion induced by fumonisin B1 in rat liver
29. Inhibitory Effects of Total Triterpenoid Saponins Isolated from the Seeds of the Tea Plant (Camellia sinensis) on Human ovarian cancer Cells
30. Anti-proliferative effect and cell cycle arrest induced by saponins extracted from tea (Camellia sinensis) flower in human ovarian cancer cells
31. Abstract 716: Chakasaponin I from tea (Camellia sinensis) flower induce anti-proliferative effect and apoptosis of cisplatin-resistant ovarian cancer cells

Carnosine

1. The anti-proliferative effect of L-carnosine correlates with a decreased expression of hypoxia inducible factor 1 alpha in human colon cancer cells
2. Carnosine and cancer: a perspective
3. Effects of l-carnosine on splenic sympathetic nerve activity and tumor proliferation
4. Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model
5. The effect of zinc sulphate and zinc carnosine on genome stability and cytotoxicity in the WIL2-NS human lymphoblastoid cell line
6. Carnosine inhibits the proliferation of human gastric cancer SGC-7901 cells through both of the mitochondrial respiration and glycolysis pathways
7. Carnosine inhibits ATP production in cells from malignant glioma
8. Promotion of crown-gall tumor growth by lysopine, octopine, nopaline, and carnosine
9. Identification of factors involved in the anti-tumor activity of carnosine on glioblastomas using a proteomics approach
10. Beneficial effects of histidine and carnosine on ethanol-induced chronic liver injury
11. Circulating carnosine dipeptidase 1 associates with weight loss and poor prognosis in gastrointestinal cancer
12. l-carnosine dipeptide overcomes acquired resistance to 5-fluorouracil in HT29 human colon cancer cells via downregulation of HIF1-alpha and induction of apoptosis
13. l-Carnosine and Human Colon Cancer
14. Analysis of plasma from prostate cancer patients links decreased carnosine dipeptidase 1 levels to lymph node metastasis
15. Circulating Carnosine Dipeptidase 1 Associates with Weight Loss and Poor Prognosis in Gastrointestinal Cancer
16. Inflammatory bowel disease preventive and curative agent containing zinc l-carnosine salt as active ingredient
17. The Anti-Proliferative Effect of L-Carnosine Correlates with a Decreased Expression of Hypoxia Inducible Factor 1 alpha in Human colon cancer Cells
18. Carnosine mitigates apoptosis and protects testicular seminiferous tubules from gamma‐radiation‐induced injury in mice
19. INFLUENCE OF CARNOSINE ON THE CARDIOTOXICITYOF DOXORUBICIN IN RABBITS DOX is used against humanneoplasms including a variety of solid tumors (e.g.head and neck tumors), breast cancer, bladder and testicular cancer, small cell lung cancer
20. Carnosine protects pancreatic beta cells and islets against oxidative stress damage
21. Prevention of radiation esophagitis by polaprezinc (zinc L-carnosine) in patients with non-small cell lung cancer who received chemoradiotherapy
22. Correction: The Anti-Proliferative Effect of L-CarnosineCorrelates with a Decreased Expression of HypoxiaInducible Factor 1 alpha in Human colon cancer Cells
23. ID: 1029 Effects of carnosine on regulation of migration and invasion in human colorectal cancer cells
24. L-Carnosine protects against Oxaliplatin-induced peripheral neuropathy in colorectal cancer patients: A perspective on targeting Nrf-2 and NF-κB pathways
25. L-carnosine for prevention of oxaliplatin-induced neuropathy in colorectal cancer patients (pts)
26. l-carnosine induces apoptosis/cell cycle arrest via suppression of NF-κB/STAT1 pathway in HCT116 colorectal cancer cells
27. Investigations on in vitro anti-carcinogenic potential of l-carnosine in liver cancer cells
28. L-Carnosine Prevents the Pro-cancerogenic Activity of Senescent Peritoneal Mesothelium Towards ovarian cancer Cells

Carnosol

1. Carnosol, a dietary diterpene, displays growth inhibitory effects in human prostate cancer PC3 cells leading to G2-phase cell cycle arrest and targets the 5′-AMP
2. Carnosol: a promising anti-cancer and anti-inflammatory agent
3. Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines
4. Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid
5. Disruption of androgen and estrogen receptor activity in prostate cancer by a novel dietary diterpene carnosol: implications for chemoprevention
6. Carnosol: a phenolic diterpene with cancer chemopreventive potential
7. Protective effect of carnosol on CCl4-induced acute liver damage in rats
8. Carnosol induces ROS-mediated beclin1-independent autophagy and apoptosis in triple negative breast cancer
9. Carnosol inhibits the invasion of B16/F10 mouse melanoma cells by suppressing metalloproteinase-9 through down-regulating nuclear factor-kappaB and c-Jun
10. Inhibition by rosemary and carnosol of 7, 12-dimethylbenz [a] anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation
11. Carnosol inhibits tumor growth and metastasis of breast cancer through inhibition of the histone acetytransferase activity of p300 and proteasome
12. Carnosol Induces ROS-Mediated Beclin1-Independent Autophagy and Apoptosis in Triple Negative Breast Cancer
13. Antitumor activity of the dietary diterpene carnosol against a panel of human cancer cell lines Carnosol decreased cell viability in human breast, ovarian, and intestinal tumor cell lines, and inhibited cancer cell adhesion on fibronectin and growth of cancer cells in suspension.
14. CYP1A1 Regulates Breast Cancer Proliferation and Survival hese findings led us to test the hypothesis that CYP1A1 promotes breast cancer progression by evaluating the effects of CYP1A1 knockdown
15. Polyphenols from the Mediterranean herb rosemary (Rosmarinus officinalis) for prostate cancer
16. Carnosol and Carnosic Acids from Salvia officinalis Inhibit Microsomal Prostaglandin E2 Synthase-1
17. Dietetic factors associated with prostate cancer. Protective effects of Mediterranean dietFactores dietéticos asociados al cáncer de próstata. Beneficios de la dieta mediterránea
18. Carnosol, radiation and melanoma: a translational possibility
19. Phytochemicals, withaferin A and carnosol, overcome pancreatic cancer stem cells as c-Met inhibitors
20. Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells
21. Comparative Study of Green Sub- and Supercritical Processes to Obtain Carnosic Acid and Carnosol-Enriched Rosemary Extracts with in Vitro Anti-Proliferative Activity on colon cancer Cells
22. Nano-liquid Chromatography-orbitrap MS-based Quantitative Proteomics Reveals Differences Between the Mechanisms of Action of Carnosic Acid and Carnosol in colon cancer Cells
23. Carnosic Acid and Carnosol Induced Apoptosis through EP4 Signaling in Human colon cancer HCT116 Cells
24. Carnosol, rosemary ingredient, induces apoptosis in adult T-cell leukemia/lymphoma cells via glutathione depletion: proteomic approach using fluorescent two-dimensional differential gel electrophoresis
25. Glutathione As Preventive and Therapeutic Target of Adult T-Cell leukemia/Lymphoma and Its Regulation by Carnosol, a Functional Food Ingredient
26. Carnosol, an Antioxidant in Rosemary, Suppresses Inducible Nitric Oxide Synthase through down-Regulating Nuclear Factor-Kappa B in Mouse Macrophages
27. Carnosol inhibits Hedgehog signaling pathway in both LNCaP and DU145 prostate cancer cell lines.

Cat’s Claw (Uncaria tomentosa)

1. The antiproliferative effects of Uncaria tomentosa extracts and fractions on the growth of breast cancer cell line.
2. Induction of apoptosis and inhibition of proliferation in human tumor cells treated with extracts of Uncaria tomentosa.
3. Cytotoxic effect of the pentacyclic oxindole alkaloid mitraphylline isolated from Uncaria tomentosa bark on human Ewing’s sarcoma and breast cancer cell lines
4. Antiproliferative effects of mitraphylline, a pentacyclic oxindole alkaloid of Uncaria tomentosa on human glioma and neuroblastoma cell lines
5. Antitumoral and antioxidant effects of a hydroalcoholic extract of cat’s claw (Uncaria tomentosa)(Willd. Ex Roem. & Schult) in an in vivo carcinosarcoma model
6. Uncaria tomentosa—adjuvant treatment for breast cancer: clinical trial
7. Treatment of chemotherapy-induced leukopenia in a rat model with aqueous extract from Uncaria tomentosa
8. Antiproliferative and pro-apoptotic effects of Uncaria tomentosa in human medullary thyroid carcinoma cells
9. An extract of Uncaria tomentosa inhibiting cell division and NF-κB activity without inducing cell death
10. Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of uncaria tomentosa for the treatment of rheumatoid arthritis.
11. Uncaria tomentosa (Cat’s Claw) Improves Quality of Life in Patients with Advanced Solid Tumors
12. Shark cartilage, cat’s claw, and other complementary breast cancer therapies
13. Cytotoxic Effect of the Pentacyclic Oxindole Alkaloid Mitraphylline Isolated from Uncaria tomentosa Bark on Human Ewing’s Sarcoma and Breast Cancer Cell Lines
14. Induction of apoptosis by Uncaria tomentosa through reactive oxygen species production, cytochrome c release, and caspases activation in human leukemia cells
15. leukemia.pdf”>Antiproliferative activity of various Uncaria tomentosa preparations on HL-60 promyelocytic leukemia cells
16. Enhanced proapoptotic response of the promyelocytic leukemia HL-60 cells treated with an Uncaria tomentosa alkaloid preparation

Catharantus roseus

1. Effect of acetylsalicylic acid on secondary metabolism ofCatharanthus roseus tumor suspension cultures
2. Cell and tissue cultures of Catharanthus roseus: a literature survey
3. Serpentine accumulation during greening in normal and tumor tissues of Catharanthus roseus
4. Targeted regulation of PI3K/Akt/mTOR/NF-κB signaling by indole compounds and their derivatives: mechanistic details and biological implications for cancer therapy
5. Indole alkaloids from Catharanthus roseus: bioproduction and their effect on human health
6. Effect of an antidiabetic extract of Catharanthus roseus on enzymic activities in streptozotocin induced diabetic rats
7. Calcium chloride effects on salinity-induced oxidative stress, proline metabolism and indole alkaloid accumulation in Catharanthus roseus
8. Effects of salt on lipid peroxidation and antioxidant enzyme activities of Catharanthus roseus suspension cells
9. Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus
10. The discovery of the vinca alkaloids—chemotherapeutic agents against cancer
11. Catharanthus roseus – Cancer fighting | Tropical Biodiversity
12. Catharanthus roseus: The Cancer-Fighting Medicine
13. Catharanthus roseus. An Anti-Cancer Plant.
14. Catharanthus roseus: A cancer-killing champion of the plant world
15. (PDF) Anticancer Alkaloids of Catharanthus roseus – ResearchGate
16. Catharanthus roseus plant is used for the treatment of lung cancer
17. Anti-Cancer Drug Discovery derived from the Madagscan periwinkle plant Catharantus roseus and Development in Brazil: Targeted Plant Collection as a Rational Strategy to Acquire Candidate Anti-Cancer Compounds
18. Ethanolic periwinkle leaf extract reduces telomerase expression in T47D cancer cells An experimental study with controls was conducted involving T47D breast cancer cells.
19. Mechanism of Action of Anticancer Herbal Medicines These include etoposide, vincristine and vinblastine from Catharantus roseus, camptothecin from Camptotheca acuminata, podophyllotoxin from Podophyllum peltatum, etc. The aim of the chapter is to describe various anticancer plants and their possible mechanisms of action in the prevention of cancer.
20. Photosynthesized gold nanoparticles from Catharanthus roseus induces caspase-mediated apoptosis in cervical cancer cells (HeLa)

Celastrol (derived from Trypterygium wilfordii)

1. Celastrol, a triterpene extracted from the Chinese “Thunder of God Vine,” is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice
2. The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma
3. Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer
4. Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB
5. Anticancer effect of celastrol on human triple negative breast cancer: possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt
6. Celastrol induces apoptosis in non-small-cell lung cancer A549 cells through activation of mitochondria-and Fas/FasL-mediated pathways
7. Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers
8. Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway
9. Celastrol isolated from Tripterygium regelii induces apoptosis through both caspase-dependent and-independent pathways in human breast cancer cells
10. Celastrol inhibits gastric cancer growth by induction of apoptosis and autophagy
11. Natural Proteasome Inhibitor Celastrol Suppresses Androgen-Independent Prostate Cancer Progression by Modulating Apoptotic Proteins and NF-kappaB
12. Celastrol Potentiates Radiotherapy by Impairment of DNA Damage Processing in Human Prostate Cancer
13. Evaluation of anticancer activity of celastrol liposomes in prostate cancer cells
14. Celastrol: Molecular targets of Thunder God Vine
15. Celastrol Suppresses Tumor Cell Growth through Targeting an AR-ERG-NF-κB Pathway in TMPRSS2/ERG Fusion Gene Expressing Prostate Cancer
16. Celastrol inhibits breast cancer cell invasion via suppression of NF-ĸB-mediated matrix metalloproteinase-9 expression.
17. Celastrol inhibits the growth of estrogen positive human breast cancer cells through modulation of estrogen receptor α
18. Celastrol induces the apoptosis of breast cancer cells and inhibits their invasion via downregulation of MMP-9
19. Celastrol suppresses breast cancer MCF-7 cell viability via the AMP-activated protein kinase (AMPK)-induced p53–polo like kinase 2 (PLK-2) pathway
20. Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor
21. Role of the eIF4E binding protein 4E‐BP1 in regulation of the sensitivity of human pancreatic cancer cells to TRAIL and celastrol‐induced apoptosis
22. Triptolide and celastrol loaded silk fibroin nanoparticles show synergistic effect against human pancreatic cancer cells†
23. Celastrol Binds to HSP90 Trigger Functional Protein Interaction Network Against pancreatic cancer
24. A novel nucleolin aptamer-celastrol conjugate (NACC) with super antitumor activity on advanced pancreatic cancer
25. Erratum to: Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor
26. A Smart Celastrol-nucleolin Aptamer Conjugate with Super Anti-tumor Activity in pancreatic cancer Cell Line
27. HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way
28. Celastrol, a novel HSP90 inhibitor, depletes Bcr–Abl and induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation
29. Celastrol and an EGCG pro-drug exhibit potent chemosensitizing activity in human leukemia cells
30. Metabolomics profiles delineate uridine deficiency contributes to mitochondria-mediated apoptosis induced by celastrol in human acute promyelocytic leukemia cells
31. Celastrol Induces Cell Apoptosis and Inhibits the Expression of the AML1-ETO/C-KIT Oncoprotein in t(8;21) leukemia
32. [Inhibition of proliferation of adult T-cell leukemia cells by celastrol].
33. Molecular Studies on Celastrol-induced Bcr-Abl Oncoprotein Degradation in Humanleukemia Cells
34. Metabolomics Reveals Cysteine Metabolism Plays a Role in Celastrol-Induced Mitochondrial Apoptosis of Acute Promyelocytic leukemia Cells
35. Inhibitation of proliferation of human acute myelogenous leukemia cells in vitro by celastrol
36. Exosomal formulation enhances therapeutic response of celastrol against lung cancer
37. Cancerous inhibitor of PP2A is targeted by natural compound celastrol for degradation in non-small-cell lung
38. Enhancement of radiation sensitivity in lung cancer cells by celastrol is mediated by inhibition of Hsp90
39. Celastrol Induces Apoptosis in Gefitinib-Resistant Non-Small Cell lung cancer Cells via Caspases-Dependent Pathways and Hsp90 Client Protein Degradation
40. ATF2 contributes to cisplatin resistance in non‐small cell lung cancer and celastrol induces cisplatin resensitization through inhibition of JNK/ATF2 pathway
41. Celastrol induces proteasomal degradation of FANCD2 to sensitize lung cancer cells to DNA crosslinking agents
42. [Effect of celastrol in inhibiting metastasis of lung cancer cells by influencing Akt signaling pathway and expressing integrins].
43. Preliminary study on fabrication, characterization and synergistic anti-lung cancer effects of self-assembled micelles of covalently conjugated celastrol–polyethylene glycol–ginsenoside Rh2
44. Celastrol improves the therapeutic efficacy of EGFR-TKIs for non-small-cell lung cancer by overcoming EGFR T790M drug resistance
45. Celastrol induces apoptosis in human colon cancer SW620 cells through species reactive oxygen
46. Abstract 2258: Celastrol shows chemopreventive properties in an inflammatory driven model for colon cancer via induction of Nrf2 transcription.
47. Effects and Mechanisms of Celastrol (CSL) on Human colon cancer Cell Line HCT-116 in vitro
48. Celastrol inhibits colon cancer cell proliferation by downregulating miR-21 and PI3K/AKT/GSK-3β pathway
49. Celastrol Suppresses Tryptophan Catabolism in Human colon cancer Cells as Revealed by Metabolic Profiling and Targeted Metabolite Analysis
50. Prooxidative Activity of Celastrol Induces Apoptosis, DNA Damage, and Cell Cycle Arrest in Drug-Resistant Human colon cancer Cells
51. Celastrol Ameliorates Ulcerative Colitis-Related colorectal cancer in Mice via Suppressing Inflammatory Responses and Epithelial-Mesenchymal Transition
52. Celastrol inhibits colorectal cancer cell proliferation and migration through suppression of MMP3 and MMP7 by the PI3K/AKT signaling pathway
53. Potent suppression of both spontaneous and carcinogen-induced colitis-associated colorectal cancer in mice by dietary celastrol supplementation
54. Celastrol inhibits colorectal cancer through TGF-β1/Smad signaling
55. Celastrol suppresses nitric oxide synthases and the angiogenesis pathway in colorectal cancer
56. LKB1 and YAP phosphorylation play important roles in Celastrol-induced β-catenin degradation in colorectal cancer
57. Celastrol Enhances the Anti-liver cancer Activity of Sorafenib
58. Celastrol inhibits migration and invasion through blocking the NF‑κB pathway in ovarian cancer cells
59. Effects of celastrol on enhancing apoptosis of ovarian cancer cells via the downregulation of microRNA‑21 and the suppression of the PI3K/Akt‑NF‑κB signaling pathway in an in vitro model of ovarian carcinoma
60. Celastrol strongly inhibits proliferation, migration and cancer stem cell properties through suppression of Pin1 in ovarian cancer cells
61. Celastrol Inhibits the Growth of ovarian cancer Cells in vitro and in vivo
62. Synthesis and biological evaluation of celastrol derivatives as anti-ovarian cancer stem cell agents
63. The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma
64. NF-Kappa B Modulation Is Involved in Celastrol Induced Human Multiple Myeloma Cell Apoptosis
65. Celastrol Inhibits Lipopolysaccharide-Induced Angiogenesis by Suppressing TLR4-Triggered Nuclear Factor-Kappa B Activation
66. Synergism between NF-kappa B inhibitor, celastrol, and XIAP inhibitor, embelin, in an acute myeloid leukemia cell line, HL-60
67. Effects of celastrol on human cervical cancer cells as revealed by ion-trap gas chromatography–mass spectrometry based metabolic profiling
68. Competitive profiling of celastrol targets in human cervical cancer HeLa cells via quantitative chemical proteomics

Celastrus Orbiculatus

1. Celastrus orbiculatus extract inhibits tumor angiogenesis by targeting vascular endothelial growth factor signaling pathway and shows potent antitumor activity
2. A New Sesquiterpene Ester from Celastrus orbiculatus Reversing Multidrug Resistance in Cancer Cells
3. Celastrus orbiculatus extract induces mitochondrial-mediated apoptosis in human hepatocellular carcinoma cells
4. Experimental study on anti-tumor effect of extractive from Celastrus orbiculatus in vivo
5. Antiinflammatory Constituents of Celastrus orbiculatus Inhibit the NF-κB Activation and NO Production
6. The effects of growth inhibition and quinone reductase activity stimulation of Celastrus orbiculatus fractions in various cancer cells
7. Celastrus orbiculatus extract triggers apoptosis and autophagy via PI3K/Akt/mTOR inhibition in human colorectal cancer cells
8. Anti-invasive effects of Celastrus Orbiculatus extract on interleukin-1 beta and tumour necrosis factor-alpha combination-stimulated fibroblast-like
9. (-)-Epiafzelechin: cyclooxygenase-1 inhibitor and anti-inflammatory agent from aerial parts of Celastrus orbiculatus
10. Antimetastatic Effects of Celastrus orbiculatus on Human Gastric Adenocarcinoma by Inhibiting Epithelial–Mesenchymal Transition and NF-κB/Snail Signaling

Chenopodium ambrosioides L

1. Ascitic and solid Ehrlich tumor inhibition by Chenopodium ambrosioides L. treatment
2. Cytotoxic effect of Argentine medicinal plant extracts on human hepatocellular carcinoma cell line
3. Studies on the anti-inflammatory and analgesic properties of Chenopodium ambrosioides leaf extract in rats
4. From popular use to pharmacological validation: a study of the anti-inflammatory, anti-nociceptive and healing effects of Chenopodium ambrosioides extract
5. Evaluation of Chenopodium ambrosioides oil as a potential source of antifungal, antiaflatoxigenic and antioxidant activity
6. Increase of cellular recruitment, phagocytosis ability and nitric oxide production induced by hydroalcoholic extract from Chenopodium ambrosioides leaves
7. Cytotoxicity of Essential Oil of Chenopodium ambrosioides L against Human Breast Cancer MCF-7 Cells
8. An overview of the anti-cancer properties of some plants used in traditional medicine in Nigeria
9. Combined effect of the essential oil from Chenopodium ambrosioides and antileishmanial drugs on promastigotes of Leishmania amazonensis
10. Effect of oral treatment with the essential oil from Chenopodium ambrosioides against cutaneous leishmaniasis in BALB/c mice, caused by Leishmania amazonensis
11. Anticancer effects of Chenopodium ambrosiodes L. essential oil on human breast cancer MCF-7 cells in vitro
12. Petroleum ether extract of Chenopodium album L. prevents cell growth and induces apoptosis of human lung cancer cells
13. Ascitic and solid Ehrlich tumor inhibition by Chenopodium … – NCBI
14. In vitro anticancer activity and cytotoxicity screening of phytochemical extracts from selected traditional Chinese medicinal plants MCF-7 breast cancer cell line [11];Ehrlich tumor [12]
15. BIOACTIVE CONSTITUENTS, PHYTOCHEMICAL AND PHARMACOLOGICAL PROPERTIES OF CHENOPODIUM ALBUM: A MIRACLE WEED The methanol extract of C. ambro leaves exhibited maximum anti-breast cancer activity.
16. Characterization and evaluation of the cytotoxic potential of the essential oil of Chenopodium ambrosioides commercial preparation of the essential oil of C. ambrosioides and analyzed in it using different strains of tumor cells in vitro (CCRF-CEM–human lymphoblastic leukemia T cells, HL60 – promyelocytic leukemia, and MDA MB-231 – breast cancer)

Cinnamomum cassia

1. Aqueous cinnamon extract (ACE-c) from the bark of Cinnamomum cassia causes apoptosis in human cervical cancer cell line
2. Antiproliferative activity of Cinnamomum cassia constituents and effects of pifithrin-alpha on their apoptotic signaling pathways in Hep G2 cells
3. Cinnamaldehyde inhibits the tumor necrosis factor-α-induced expression of cell adhesion molecules in endothelial cells by suppressing NF-κB activation
4. Cytotoxic effect of trans-cinnamaldehyde from cinnamomum osmophloeum leaves on Human cancer cell lines
5. The ability of an ethanol extract of Cinnamomum cassia to inhibit Src and spleen tyrosine kinase activity contributes to its anti-inflammatory action
6. Anti-inflammatory activities of Cinnamomum cassia constituents in vitro and in vivo
7. Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1
8. Antitumor effect of the cinnamaldehyde derivative CB403 through the arrest of cell cycle progression in the G2/M phase
9. Inhibition of benzo[a]pyrene- and cyclophoshamide-induced mutagenicity by Cinnamomum cassia
10. Involvement of 5-HT1A and GABAA receptors in the anxiolytic-like effects of Cinnamomum cassia in mice
11. Cinnamomum cassia extracts reverses TGFâ β1â induced epithelialâ mesenchymal transition in human lung adenocarcinoma cells and suppresses tumor growth
12. Cinnamomum cassia extracts reverses TGF‐β1‐induced epithelial–mesenchymal transition in human lung adenocarcinoma cells and suppresses tumor growth
13. Early growth response protein 1 upregulation and nuclear translocation by 2′-benzoyloxycinnamaldehyde from Cinnamomum cassia induces prostate cancer cell death
14. Stimulatory effects of extract prepared from the bark of Cinnamomum cassia blume on the function of osteoblastic MC3T3‐E1 cells significantly induced the growth of MCF‐7 cells, an ER‐positive human breast cancer cell line,
15. 2-Hydroxycinnamaldehyde inhibits the epithelial-mesenchymal transition in breast cancer cells
16. Cinnamomum cassia Suppresses Caspase-9 through Stimulation of AKT1 in MCF-7 Cells but Not in MDA-MB-231 Cells In the present study, particular differences in the mechanism of the anti-proliferative property of C. cassia on two breast cancer cell lines,
17. Cinnamaldehydes in Cancer Chemotherapy Finally, the application of cinnamaldehydes in treating various types of cancer, including breast, prostate, and colon cancers, has been discussed in detail.
18. Methanol Extract of Cinnamomum cassia Represses Cellular Proliferation and Gli-mediated Transcription in PANC-1 Human pancreatic cancer Cells
19. Cytotoxic activity of the twigs of Cinnamomum cassia through the suppression of cell proliferation and the induction of apoptosis in human colorectal cancer cells
20. Young Stem of Cinnamomum cassia Blume Suppresses Wnt Signaling Through Downregulation of β-catenin and TCF4 in Human colorectal cancer Cells
21. Mechanistic Study of Hot Water Extracts from Young Stem of Cinnamomum cassia Blume Against Human colorectal cancer Cells -Transcriptional Inhibition and Proteasomal Degradation of Cyclin D1
22. Mechanistic Study for Anti-cancer Activity of Hot Water Extracts from Twigs of Cinnamomum cassia Against Human colorectal cancer Cells
23. Hot Water Extracts from Young Stem of Cinnamomum cassia Induces ROS-Dependent Apoptosis in Human colorectal cancer Cells
24. Cinnamomum Cassia Extracts Suppress Human lung cancer Cells Invasion by Reducing u-PA/MMP Expression through the FAK to ERK Pathways
25. Water-extracted branch of Cinnamomum cassia promotes lung cancer cell apoptosis by inhibiting pyruvate dehydrogenase kinase activity

Commiphora myrrha

1. Secondary metabolites from Commiphora opobalsamum and their antiproliferative effect on human prostate cancer cells
2. Anti-inflammatory and analgesic activity of different extracts of Commiphora myrrha
3. Cytotoxicity activity of extracts and compounds from Commiphora myrrha resin against human gynecologic cancer cells
4. Composition and potential anticancer activities of essential oils obtained from myrrh and frankincense
5. In vitro cytotoxic and anti-inflammatory effects of myrrh oil on human gingival fibroblasts and epithelial cells
6. Evaluation of the anti-inflammatory and analgesic properties of individual and combined extracts from Commiphora myrrha, and Boswellia carterii
7. Hepatoprotective effect of Commiphora myrrha against d-GalN/LPS-induced hepatic injury in a rat model through attenuation of pro inflammatory cytokines
8. Sesquiterpenoids from the resinous exudates of Commiphora myrrha and their neuroprotective effects
9. Four new sesquiterpenes from Commiphora myrrha and their neuroprotective effects
10. In vitro anticancer activity of twelve Chinese medicinal herbs
11. 3β-triol, a cycloartane-type triterpenoid from the resinous exudates of Commiphora myrrha, induces apoptosis in human prostatic cancer PC-3 cells
12. Citrate reduced gold nanoparticles conjugated with Boswellia sacra and Commiphora myrrha to cause cytotoxicity in breast cancer cells
13. Commiphora myrrha In vitro anticancer activity of twelve Chinese medicinal herbs Five human and three murine cancer cell lines representing different tissues (breast, lung, pancreas and prostate) were used.
14. Cytotoxicity activity of extracts and compounds from Commiphora myrrha resin against human gynecologic cancer cells
15. A Triterpenoid and Sesquiterpenoids from the Resinous Exudates of Commiphora myrrha he isolated compounds 1–6 were evaluated for their cytotoxicity against the PC3 and DU145 human prostate tumor cell lines.
16. Furanosesquiterpenoids of Commiphora myrrha Compound 1 exhibited weak cytotoxic activity against a MCF-7 breast tumor cell line in a clonogenic assay,
17. Sesquiterpenoids from myrrh inhibit androgen receptor expression and function in human prostate cancer cells
18. Review on the Applications and Molecular Mechanisms of Xihuang Pill in Tumor Treatment XH has clinical effects on non-Hodgkin lymphoma, breast cancer, gastric cancer, liver cancer, and bone metastasis.

Coprinus comatus

1. Coprinus comatus and Ganoderma lucidum interfere with androgen receptor function in LNCaP prostate cancer cells
2. In vitro effects on proliferation, apoptosis and colony inhibition in ER-dependent and ER-independent human breast cancer cells by selected mushroom species
3. Coprinus comatus (Higher Basidiomycetes) Fruit Bodies on Cell Growth of Human Ovarian Cancer
4. Ethyl acetate extracts of submerged cultured mycelium of higher Basidiomycetes mushrooms inhibit human ovarian cancer cell growth
5. The Shaggy Inc Cap Medicinal Mushroom, Coprinus comatus (OFMull.: Fr.) Pers. (Agaricomycetideae) Substances Interfere with H2O2 Induction of the NF-κB
6. The culinary-medicinal mushroom Coprinus comatus as a natural antiandrogenic modulator
7. Coprinus comatus cap inhibits adipocyte differentiation via regulation of PPARγ and Akt signaling pathway
8. Inhibition of the androgen receptor activity by Coprinus comatus substances
9. Protective effect of selenium-polysaccharides from the mycelia of Coprinus comatus on alloxan-induced oxidative stress in mice
10. Anti-oxidative activity of an aqueous suspension of commercial preparation of the mushroom Coprinus comatus
11. The shaggy ink cap medicinal mushroom, Coprinus comatus (higher Basidiomycetes) extract induces apoptosis in ovarian cancer cells
12. The shaggy ink cap medicinal mushroom, Coprinus comatus (higher Basidiomycetes) extract induces apoptosis in ovarian cancer cells via extrinsic and intrinsic
13. Coprinus comatus and Ganoderma lucidum interfere with androgen receptor function in LNCaP prostate cancer cells
14. leukemia-cell-uf-health-researchers-find/”>Common, edible mushroom has potential to kill one type of leukemia cell, UF Health researchers find
15. Coprinus comatus and Ganoderma lucidum interfere with androgen receptor function in LNCaP prostate cancer cells
16. The Culinary-Medicinal Mushroom Coprinus comatus as a Natural Antiandrogenic Modulator CC734-H was able to reduce AR levels and prostate-specific antigen gene expression in the LNCaP-treated cell line.
17. Coprinus comatus, In vitro effects on proliferation, apoptosis and colony inhibition in ER-dependent and ER-independent human breast cancer cells by selected mushroom species
18. The Shaggy Ink Cap Medicinal Mushroom,Coprinus comatus (Higher Basidiomycetes) Extract Induces Apoptosis in ovarian cancer Cells via Extrinsic and Intrinsic Apoptotic Pathways
19. A Robust Cysteine-Deficient Chitinase-like Antifungal Protein from Inner Shoots of the Edible Chive Coprinus comatus It exerted some cytotoxic effect on breast cancer cells and was inhibitory toward HIV-1 reverse transcriptase.

Corchorus olitorius

1. Antitumor promoters in leaves of jute (Corchorus capsularis and Corchorus olitorius)
2. Protective effect of Corchorus olitorius leaves on sodium arsenite-induced toxicity in experimental rats
3. Anti-inflammatory and cytotoxic activities of dietary phenolics isolated from Corchorus olitorius and Vitis vinifera
4. Antiobesity effect of polyphenolic compounds from molokheiya (Corchorus olitorius L.) leaves in LDL receptor-deficient mice
5. Induction of apoptosis by ethanolic extract of Corchorus olitorius leaf in human hepatocellular carcinoma (HepG2) cells via a mitochondria-dependent
6. Protective effect of Corchorus olitorius leaves against arsenic-induced oxidative stress in rat brain
7. Phenolic Antioxidants from the Leaves of Corchorus olitorius L.
8. Anti-inflammatory effects of phenolic crude extracts from five fractions of Corchorus Olitorius L.
9. Toxic effects of lead exposure in Wistar rats: involvement of oxidative stress and the beneficial role of edible jute (Corchorus olitorius) leaves
10. Molokhia (Corchorus olitorius L.) extract suppresses transformation of the aryl hydrocarbon receptor induced by dioxins
11. Polyphenolic compounds with anti-tumour potential from Corchorus olitorius (L.) Tiliaceae, a Nigerian leaf vegetable.
12. CYTOTOXICITY OF Corchorus Olitorius Linn. AQUEOUS LEAF EXTRACT AGAINST HUMAN CARCINOMA CELLS
13. Corchorus olitorius Leaf in Human Hepatocellular Carcinoma (HepG2) Cells via a Mitochondria-Dependent Pathway
14. Chemical Constituents of Corchorus olitorius L
15. Antitumor Promoters in Leaves of Jute (Corchorus capsularis and Corchorus olitorius)
16. Induction of Apoptosis by Ethanolic Extract of Corchorus olitorius Leaf in Human Hepatocellular Carcinoma (HepG2) Cells via a Mitochondria-Dependent Pathway
17. Aqueous extract of Corchorus olitorius decreases cytotoxicity of afl atoxin B1 and fumonisin B1 in H4IIE-luc cells
18. Bioactivities of gold and iron oxide nanoparticles biosynthesized from the edible plant Corchorus olitorius against MCF 7 breast cancer cell lines in comparison with the leaf extract effect
19. Successful Green Synthesis of Gold Nanoparticles using a Corchorus olitorius Extract and Their Antiproliferative Effect in Cancer Cells An in vitro cytotoxic assay of the biocompatible Au NPs revealed a strong cytotoxic activity in three human cancer cell lines, namely, colon carcinoma HCT-116, hepatocellular carcinoma HepG-2, and breast adenocarcinoma MCF-7.
20. Semen quality, hormone profile and histological changes in male albino rats treated with Corchorus olitorius leaf extract A significant fall in relative organ weights for the testes and prostate was observed following high-dose treatment (p<0.05).
21. Phenolic content and antioxidant activity of selected Ugandan traditional medicinal foods carotenoids in the various fruits and vege-tables may also reduce the risk of prostate cancer (Jian et al., 2005) while flavonoids in tea act against cardiovas-cular diseases
22. Assessment of Soil Fertility, Fibre Production, Nutritional and Medicinal Values of Jute Leaves as Affected by Indigenous Organic Matters Management As a result of the availability of ascorbic acid in all the vegetables, they can be used in herbal medicine for the treatment of common cold and other diseases like prostate cancer [34].

Cordycepin

1. The apoptotic effect of cordycepin on human OEC-M1 oral cancer cell line
2. Anti-cancer effect and apoptosis induction of cordycepin through DR3 pathway in the human colonic cancer cell HT-29
3. Cordycepin causes p21WAF1-mediated G2/M cell-cycle arrest by regulating c-Jun N-terminal kinase activation in human bladder cancer cells
4. Effect of cordycepin on nucleic acid metabolism in L5178Y cells and on nucleic acid-synthesizing enzyme systems
5. Antitumor effect of cordycepin (3′-deoxyadenosine) on mouse melanoma and lung carcinoma cells involves adenosine A3 receptor stimulation
6. Inhibitory effects of ethyl acetate extract of Cordyceps sinensis mycelium on various cancer cells in culture and B16 melanoma in C57BL/6 mice
7. Cordycepin-induced apoptosis and autophagy in breast cancer cells are independent of the estrogen receptor
8. Cordycepin suppresses TNF‐alpha‐induced invasion, migration and matrix metalloproteinase‐9 expression in human bladder cancer cells
9. Effect of cordycepin (3′-deoxyadenosine) on hematogenic lung metastatic model mice
10. c-Jun N-terminal kinase 1 is required for cordycepin-mediated induction of G2/M cell-cycle arrest via p21WAF1 expression in human colon cancer cells
11. Cordycepin inhibits breast cancer migration and invasion by targeting epithelial to mesenchymal transition-inducing transcription factors (EMT-TFs)
12. Apoptosis and inhibition of proliferation of cancer cells induced by cordycepin
13. Apoptosis induction of human prostate carcinoma cells by cordycepin through reactive oxygen species‑mediated mitochondrial death pathway
14. Inhibition of migration and invasion of LNCaP human prostate carcinoma cells by cordycepin through inactivation of Akt
15. Involvement of autophagy in cordycepin-induced apoptosis in human prostate carcinoma LNCaP cells
16. Cordycepin inhibits TPA-induced matrix metalloproteinase-9 expression by suppressing the MAPK/AP-1 pathway in MCF-7 human breast cancer cells
17. Synergistic property of cordycepin in cultivated Cordyceps militaris-mediated apoptosis in human leukemia cells
18. The nucleoside antagonist cordycepin causes DNA double strand breaks in breast cancer cells
19. Cordycepin Blocks Lung Injury-Associated Inflammation and Promotes BRCA1-Deficient Breast Cancer Cell Killing by Effectively Inhibiting PARP
20. Polyadenylate polymerase modulations in human epithelioid cervix and breast cancer cell lines, treated with etoposide or cordycepin, follow cell cycle rather than apoptosis induction
21. Cordycepin, a Natural Antineoplastic Agent, Induces Apoptosis of Breast Cancer Cells via Caspase-dependent Pathways
22. RNA‐directed agent, cordycepin, induces cell death in multiple myeloma cells s a result of the availability of ascorbic acid in all the vegetables, they can be used in herbal medicine for the treatment of common cold and other diseases like prostate cancer
23. Cordycepin induces apoptosis in human pancreatic cancer cells via the mitochondrial-mediated intrinsic pathway and suppresses tumor growth in vivo
24. The mechanism of cordycepin in inhibition of pancreatic cancer stem cells proliferation and metastasis
25. Cordycepin induces Bax‑dependent apoptosis in colorectal cancer cells
26. Toxicity evaluation of cordycepin and its delivery system for sustained in vitro anti-lung cancer activity
27. Cordycepin Induces Apoptosis and Inhibits Proliferation of Human lung cancer Cell Line H1975 via Inhibiting the Phosphorylation of EGFR
28. Cordycepin induces human lung cancer cell apoptosis by inhibiting nitric oxide mediated ERK/Slug signaling pathway
29. Apoptotic effect of cordycepin on A549 human lung cancer cell line
30. The effects of cordycepin on the cell proliferation, migration and apoptosis in human lung cancer cell lines A549 and NCI‐H460
31. The inhibitory effect of Cordycepin on the proliferation of cisplatin-resistant A549 lung cancer cells
32. Cordycepin regulates the malignant biological behaviors of lung cancer cell lines A549
33. Effect of cordycepin on non-small cell lung cancer cell line H358 proliferation and related gene expression
34. Cordycepin Inhibits Drug-resistance Non-small Cell lung cancer Progression by Activating AMPK Signaling Pathway
35. Inhibitory effect on B16/F10 mouse melanoma cell and HT-29 human colon cancer cell proliferation and cordycepin content of the butanol extract of Paecilomyces militaris
36. Cordycepin Induces Apoptosis through DR3 Pathway in Human colon cancer HT-29
37. Induction of apoptosis by cordycepin in ADA-inhibited TdT-positive leukemia cells.
38. Induction of apoptosis by cordycepin via reactive oxygen species generation in human leukemia cells
39. Cordycepin/Hydroxyurea Synergy Allows Low Dosage Efficacy of Cordycepin in MOLT-4 leukemia Cells
40. Cordycepin Regulates GSK-3β/β-Catenin Signaling in Human leukemia Cells
41. Cordycepin induces cell cycle arrest and apoptosis by inducing DNA damage and up-regulation of p53 in leukemia cells
42. Cordycepin disrupts leukemia association with mesenchymal stromal cells and eliminates leukemia stem cell activity
43. Synergistic effect of HMGB1 knockdown and cordycepin in the K562 human chronic myeloid leukemia cell line
44. Cordycepin induces apoptosis of human acute monocytic leukemia cells via downregulation of the ERK/Akt signaling pathway
45. Induction of apoptosis by cordycepin in human leukemia U937 and THP-1 cells
46. Effect of Domestic Cordycepin on NB4 leukemia Cell Proliferation and Apoptosis
47. Towards specific therapy in TdT-positive leukemia: Role of cordycepin
48. Induction of apoptosis by cordycepin via ROS generation in human leukemia cells
49. Induction of Apoptosis by Cordycepin via Reactive Oxygen Species Generation in Human leukemia Cells
50. Cordycepin induces apoptosis in human liver cancer HepG2 cells through extrinsic and intrinsic signaling pathways
51. Optimal conditions for cordycepin production in surface liquid-cultured Cordyceps militaris treated with porcine liver extracts for suppression of oral cancer
52. Targeted Delivery of Cordycepin to liver cancer Cells Using Transferrin-conjugated Liposomes
53. The inhibition of cordycepin on cancer stemness in TGF-beta induced chemo-resistant ovarian cancer cell
54. Cordycepin induces apoptosis of human ovarian cancer cells by inhibiting CCL5-mediated Akt/NF-κB signaling pathway
55. Abstract 709: Cordycepin induces apoptosis of human ovarian cancer cells by inhibiting CCL5-mediated Akt/NF-κB signaling pathway
56. Cordycepin induces apoptotic cell death of human brain cancer through the modulation of autophagy
57. Packaging cordycepin phycocyanin micelles for the inhibition of brain cancer

Cordyceps militaris

1. Effects of Cordyceps militaris extract on angiogenesis and tumor growth.
2. Inhibitory effect of Cordyceps sinensis on spontaneous liver metastasis of Lewis lung carcinoma and B16 melanoma cells in syngeneic mice
3. Anti-tumor activity of the fermentation broth of Cordyceps militaris cultured in the medium of Radix astragali
4. Induction of apoptosis and inhibition of telomerase activity in human lung carcinoma cells by the water extract of Cordyceps militaris
5. Constituents isolated from Cordyceps militaris suppress enhanced inflammatory mediator’s production and human cancer cell proliferation
6. Growth inhibition of U937 leukemia cells by aqueous extract of Cordyceps militaris through induction of apoptosis
7. Induction of apoptosis by aqueous extract of Cordyceps militaris through activation of caspases and inactivation of Akt in human breast cancer MDA-MB-231 Cells.
8. Comparison of Protective Effects between Cultured Cordyceps militaris and Natural Cordyceps sinensis against Oxidative Damage
9. Production of exo-polymers by submerged mycelial culture of Cordyceps militaris and its hypolipidemic effect
10. The methanolic extract of Cordyceps militaris (L.) Link fruiting body shows antioxidant, antibacterial, antifungal and antihuman tumor cell lines properties
11. Cordyceps militaris inhibit malignant transformation and proliferation by decreasing EGFR and IL-17RA signaling in a murine oral cancer
12. Cordyceps militaris (L.) link fruiting body reduces the growth of a non-small cell lung cancer cell line by increasing cellular levels of p53 and p21
13. Antifungal and Anticancer Activities of a Protein from the Mushroom Cordyceps militaris exhibited cytotoxicity against human breast and bladder cancer cells.
14. Cordyceps militaris and mycelial fermentation induced apoptosis and autophagy of human glioblastoma cells PTEN coordinates the G1 arrest of breast cancer cells by downregulating cyclin D1 via its protein phosphatase activity and upregulating p27 via its lipid phosphatase activity
15. Cordyceps Militaris Attenuates Oxidative Stress Induced Cell Damage in Pancreatic Beta-cells
16. Induction of Apoptosis by Cordyceps militaris through Activation of Caspase-3 in leukemia HL-60 Cells
17. Induction of apoptosis by Cordyceps militaris fraction in human chronic myeloid leukemia K562 cells involved with mitochondrial dysfunction
18. Anticancer Efficacy of Cordyceps militaris Ethanol Extract in a Xenografted leukemia Model
19. Increased Pro-apoptotic Effects of Hybrided Cordyceps militaris in U937 Human leukemia Cells
20. Cordyceps militaris (L.) Link Fruiting Body Reduces the Growth of a Non-Small Cell lung cancer Cell Line by Increasing Cellular Levels of p53 and p21
21. Bioassay-Guided Separation and Identification of a New Anti-lung cancer Compound from Cordyceps militaris by Means of Off-Line Two-Dimensional Preparative Chromatography, Real-Time Cell Analysis, and X-ray Single-Crystal Diffraction
22. Induction of G2/M Arrest of the Cell Cycle by Aqueous Extract of Cordyceps militaris in A549 Human Non-small-cell lung cancer Cells
23. The Extract of Cordyceps Militaris Inhibited the Proliferation of Cisplatin-Resistant A549 lung cancer Cells by Downregulation of H-Ras
24. Cordyceps militaris fraction inhibits the invasion and metastasis of lung cancer cells through the protein kinase B/glycogen synthase kinase 3β/β‑catenin signaling pathway
25. Cordyceps militaris Grown on Germinated Soybean Induces G2/M Cell Cycle Arrest through Downregulation of Cyclin B1 and Cdc25c in Human colon cancer HT-29 Cells
26. Cordyceps militaris Grown on Germinated Soybean Suppresses KRAS-Driven colorectal cancer by Inhibiting the RAS/ERK Pathway
27. Effects of Cordyceps militaris on CCl4
    – Induced Liver Damage and Cancer Cell (HepG2 Cell) Growth
28. Green synthesis of gold nanoparticles using a Cordyceps militaris extract and their antiproliferative effect in liver cancer cells (HepG2)
29. Anticancer Effects of Cordyceps Militaris Extract in Human ovarian cancer Cells via ADORA2B (P05-012-19)

Crocus sativus (Saffron)

1. Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.)
2. Crocin from Crocus sativus possesses significant anti-proliferation effects on human colorectal cancer cells
3. Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro
4. Protective effect of saffron (Crocus sativus L.) aqueous extract against genetic damage induced by anti-tumor agents in mice
5. Use of in vitro assays to assess the potential antiproliferative and cytotoxic effects of saffron (Crocus sativus L.) in human lung cancer cell line
6. Biomedical properties of saffron and its potential use in cancer therapy and chemoprevention trials
7. Protective effects of saffron (Crocus sativus Linn.) on genotoxins‐induced oxidative stress in Swiss albino mice
8. The cytolytic effect of a glycoconjugate extracted from corms of saffron plant (Crocus sativus) on human cell lines in culture
9. Suppression of Pulmonary Tumor Promotion and Induction of Apoptosis by Crocus sativus L. Extraction
10. DNA fragmentation and cell cycle arrest: a hallmark of apoptosis induced by crocin from kashmiri saffron in a human pancreatic cancer cell line
11. Crocus sativus L.(saffron) for cancer chemoprevention: a mini review Based on these findings investigators recommend that these agents could potentially be used as a chemopreventive as well as a chemotherapeutic agent for prostate cancer management
12. Crocus Sativus Stigma Extract and Its Major Constituent Crocin Possess Significant Antiproliferative Properties Against Human Prostate Cancer
13. DNA fragmentation and apoptosis induced by safranal in human prostate cancer cell line
14. Antitumor Effects of Saffron-Derived Carotenoids in Prostate Cancer Cell Models
15. Crocin from Kashmiri Saffron (Crocus sativus) Induces in Vitroand in Vivo Xenograft Growth Inhibition of Dalton’sLymphoma (DLA) in Mice
16. ContributionofSelectedMedicinalPlantsforCancerPreventionandTherapy contains components that inhibit proli-feration and induce apoptosis in human prostate epi-thelial cell lines.
17. Inhibition of Breast Cancer Cell Proliferation by Style Constituents of Different Crocus Species
18. Anticarcinogenic effect of saffron (Crocus sativus L.) and its ingredients
19. The Synergic Effects of Crocus Sativus L. and Low Frequency Electromagnetic Field on VEGFR2 Gene Expression in Human Breast Cancer Cells
20. Role of saffron and its constituents on cancer chemoprevention
21. The Cytolytic Effect of a Glycoconjugate Extracted from Corms of Saffron Plant (Crocus sativus) on Human Cell Lines in Culture
22. DNA Fragmentation and Cell Cycle Arrest: A Hallmark of Apoptosis Induced by Crocin from Kashmiri Saffron in a Human pancreatic cancer Cell line
23. Crocetin, a carotenoid compound isolated from Saffron, inhibits cell proliferation and tumor formation in pancreatic cancer
24. Abstract 5397: Crocetin, a carotenoid compound derived from Saffron, enhances antitumor effects of paclitaxol and cisplatin in pancreatic cancer
25. Abstract #1775: Crocetin, a carotenoid compound derived from saffron, antagonizes the anticancer effects of gemcitabine in pancreatic cancer
26. Crocus sativus L. (Saffron) Stigma Aqueous Extract Induces Apoptosis in Alveolar Human lung cancer Cells through Caspase-Dependent Pathways Activation
27. Distinct Pro-Apoptotic Properties of Zhejiang Saffron against Human lung cancer Via a Caspase-8-9-3 Cascade
28. Su1944 – Metastatic Associated colon cancer 1 (MACC1) Inhibition and Gut Microbiome Alteration by Saffron
29. The anticancer effect of saffron in two p53 isogenic colorectal cancer cell lines
30. Abstract 1607: Saffron restricts MACC1-dependent cell proliferation and motility of colorectal cancer cells, and alters the microbiome structure
31. In vitro antiproliferative activity of saffron extracts against human acute lymphoblastic T-cell human leukemia
32. Safranal, a Crocus sativus L constituent suppresses the growth of K-562 cells of chronic myelogenous leukemia. In silico and in vitro study
33. Saffron-Based Crocin Prevents Early Lesions of liver cancer: In vivo, In vitro and Network Analyses
34. Saffron offers protection from liver cancer
35. Saffron carotenoids inhibit STAT3 activation and promote apoptotic progression in IL-6-stimulated liver cancer cells
36. Saffron offers protection from liver cancer
37. Abstract 3684: Saffron protects against liver cancer in animal model: Molecular and imaging insights
38. Saffron-based crocin prevents early lesions of liver cancer: In vivo, in vitro and in silico analyses
39. Body & brain: Saffron fights liver cancer: Yellow spice inhibits key cell‐proliferation proteins

Curcuma wenyujin

1. Potential Anti-Cancer Activities of Furanodiene, A Sesquiterpene from Curcuma wenyujin
2. Reversal of multidrug resistance in human breast cancer cells by Curcuma wenyujin and Chrysanthemum indicum
3. Curcuma wenyujin extract induces apoptosis and inhibits proliferation of human cervical cancer cells in vitro and in vivo
4. Antitumour effects of isocurcumenol isolated from Curcuma zedoaria rhizomes on human and murine cancer cells
5. Essential oil of Curcuma wenyujin induces apoptosis in human hepatoma cells
6. Curcuma wenyujin at different stages of tumor progression in an imageable orthotopic nude mouse model of metastatic human ovarian cancer
7. Reversal effects of traditional Chinese herbs on multidrug resistance in cancer cells
8. Guaiane-type sesquiterpenes from Curcuma wenyujin and their inhibitory effects on nitric oxide production
9. Curcumolide, a unique sesquiterpenoid with anti-inflammatory properties from Curcuma wenyujin
10. The synthesis and anti-proliferative effects of β-elemene derivatives with mTOR inhibition activity
11. Curcuma wenyujin Diterpenoid compound C fought against gastric cancer: an experimental study
12. Tetrahydrocurcumin‑induced autophagy via suppression of PI3K/Akt/mTOR in non‑small cell lung carcinoma cells
13. Anti-tumor potential of ethanol extract of Curcuma phaeocaulis Valeton against breast cancer cells
14. Furanodiene, a Natural Product, Inhibits Breast Cancer Growth Both in vitro and in vivo
15. Curcumol triggers apoptosis of p53 mutant triple-negative human breast cancer MDA-MB 231 cells via activation of p73 and PUMA
16. Curcuma wenyujin Extract Induces Apoptosis and Inhibits Proliferation of Human Cervical Cancer Cells In Vitro and In Vivo
17. Discovering Bisdemethoxycurcumin from Curcuma longa rhizome as a potent small molecule inhibitor of human pancreatic α-amylase, a target for type-2 diabetes
18. In vitro modulation of pancreatic insulin secretion, extrapancreatic insulin action and peptide glycation by Curcuma longa aqueous extracts
19. Deciphering the Inactivation of Human Pancreatic α-Amylase, an Antidiabetic Target, by Bisdemethoxycurcumin, a Small Molecule Inhibitor, Isolated from Curcuma longa
20. Effect of chelidonium, curcuma, absinth and Carduus marianus on the bile and pancreatic secretion in liver diseases
21. [Clinico-experimental studies on the secretion of bile, pancreatic and gastric juice under the influence of phytocholagogous agents of a suspension of Carduus marianus, Chelidonium and Curcuma].
22. Turmeric (Curcuma longa) Effects on Pancreatic β Cell Population and Glucose Level in Rat Diabetic Model
23. Effect of Diterpenoid Curcumrinol C from Ether Extract of Curcuma Wenyujin on Proliferation of Human colon cancer Cells SW620

Curcumin

1. Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer
2. Fabrication of curcumin encapsulated PLGA nanoparticles for improved therapeutic effects in metastatic cancer cells
3. Curcumin and cancer: an “old-age” disease with an “age-old” solution
4. Anti cancer effects of curcumin: cycle of life and death
5. Liposomal curcumin with and without oxaliplatin: effects on cell growth, apoptosis, and angiogenesis in colorectal cancer
6. Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3
7. Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes
8. Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials
9. Curcumin and quercetin, upon azoxymethane-induced colon cancer and 7, 12-dimethylbenz[a]anthracene-induced mammary cancer
10. Curcumin as an anti-cancer agent: review of the gap between basic and clinical applications
11. Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines
12. Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo
13. β-Cyclodextrin-curcumin self-assembly enhances curcumin delivery in prostate cancer cells
14. Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice
15. Chemopreventive potential of curcumin in prostate cancer
16. Curcumin Suppresses the Paclitaxel-Induced Nuclear Factor-κB Pathway in Breast Cancer Cells and Inhibits Lung Metastasis of Human Breast Cancer in Nude Mice
17. Curcumin induces apoptosis in human breast cancer cells through p53‐dependent Bax induction
18. Targeting breast stem cells with the cancer preventive compounds curcumin and piperine
19. Dietary Curcumin Inhibits Chemotherapy-induced Apoptosis in Models of Human Breast Cancer
20. The Chemopreventive Polyphenol Curcumin Prevents Hematogenous Breast Cancer Metastases in Immunodeficient Mice
21. Phase II Trial of Curcumin in Patients with Advanced pancreatic cancer
22. Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells
23. Curcumin Potentiates Antitumor Activity of Gemcitabine in an Orthotopic Model of pancreatic cancer through Suppression of Proliferation, Angiogenesis, and Inhibition of Nuclear Factor-κB–Regulated Gene Products
24. Curcumin and Gemcitabine in Patients With Advanced pancreatic cancer
25. Gemcitabine Sensitivity Can Be Induced in pancreatic cancer Cells through Modulation of miR-200 and miR-21 Expression by Curcumin or Its Analogue CDF
26. A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer
27. Curcumin Analogue CDF Inhibits Pancreatic Tumor Growth by Switching on Suppressor microRNAs and Attenuating EZH2 Expression
28. Retracted: Notch‐1 down‐regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells
29. Inhibition of NFκB and pancreatic cancer Cell and Tumor Growth by Curcumin Is Dependent on Specificity Protein Down-regulation
30. Curcumin Augments Gemcitabine Cytotoxic Effect on Pancreatic Adenocarcinoma Cell Lines
31. Systemic Administration of Polymeric Nanoparticle-Encapsulated Curcumin (NanoCurc) Blocks Tumor Growth and Metastases in Preclinical Models of pancreatic cancer
32. Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells
33. Curcumin, an antioxidant and anti-tumor promoter, induces apoptosis in human leukemia cells
34. Curcumin Suppresses Activation of NF-κB and AP-1 Induced by Phorbol Ester in Cultured Human Promyelocytic leukemia Cells
35. Induction of Apoptosis by Garcinol and Curcumin through Cytochrome c Release and Activation of Caspases in Human leukemia HL-60 Cells
36. Curcumin induces pro-apoptotic endoplasmic reticulum stress in human leukemia HL-60 cells
37. Curcumin Down-Regulates DNA Methyltransferase 1 and Plays an Anti-Leukemic Role in Acute Myeloid leukemia
38. Curcumin induces growth-arrest and apoptosis in association with the inhibition of constitutively active JAK–STAT pathway in T cell leukemia
39. Curcumin-induced Cell Cycle Arrest and Apoptosis in Human Acute Promyelocytic leukemia HL-60 Cells via MMP Changes and Caspase-3 Activation
40. Curcumin Inhibits Prosurvival Pathways in Chronic Lymphocytic leukemia B Cells and May Overcome Their Stromal Protection in Combination with f
41. Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells
42. Induction of apoptosis in human lung cancer cells by curcumin
43. Curcumin Inhibits lung cancer Cell Invasion and Metastasis through the Tumor Suppressor HLJ1
44. Curcumin Induces Apoptosis in Human Non-small Cell lung cancer NCI-H460 Cells through ER Stress and Caspase Cascade- and Mitochondria-dependent Pathways
45. Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF)
46. Curcumin Blocks Small Cell lung cancer Cells Migration, Invasion, Angiogenesis, Cell Cycle and Neoplasia through Janus Kinase-STAT3 Signalling Pathway
47. Curcumin promotes apoptosis by activating the p53-miR-192-5p/215-XIAP pathway in non-small cell lung cancer
48. Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice
49. Curcumin and lung cancer—a review
50. Curcumin inhibits lung cancer cell migration and invasion through Rac1-dependent signaling pathway
51. Curcumin: A Novel Stat 3 Pathway Inhibitor for Chemoprevention of lung cancer
52. Curcumin for chemoprevention of colon cancer
53. Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells.
54. Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells
55. Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo
56. Modulation of Apoptosis by Sulindac, Curcumin, Phenylethyl-3-methylcaffeate, and 6-Phenylhexyl Isothiocyanate: Apoptotic Index as a Biomarker in colon cancer Chemoprevention and Promotion
57. β-Catenin-mediated transactivation and cell–cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells
58. Genetic Reprogramming in Pathways of Colonic Cell Maturation Induced by Short Chain Fatty Acids: Comparison with Trichostatin A, Sulindac, and Curcumin and Implications for Chemoprevention of colon cancer
59. Curcumin Inhibits the Proteasome Activity in Human colon cancer Cells In vitro and In vivo
60. Elimination of colon cancer Stem-Like Cells by the Combination of Curcumin and FOLFOX
61. Curcumin Synergizes With Resveratrol to Inhibit colon cancer
62. Chemotherapeutic Potential of Curcumin for colorectal cancer
63. Celecoxib and Curcumin Synergistically Inhibit the Growth of colorectal cancer Cells
64. Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer
65. Upregulation of p53 Expression in Patients with colorectal cancer by Administration of Curcumin
66. Curcumin Sensitizes Human colorectal cancer Xenografts in Nude Mice to γ-Radiation by Targeting Nuclear Factor-κB–Regulated Gene Products
67. Curcumin Modulates the Radiosensitivity of colorectal cancer Cells by Suppressing Constitutive and Inducible NF-κB Activity
68. New mechanisms and therapeutic potential of curcumin for colorectal cancer
69. Curcumin Modulates DNA Methylation in colorectal cancer Cells
70. Synergistic Role of Curcumin With Current Therapeutics in colorectal cancer: Minireview
71. Curcumin and liver cancer: A Review
72. Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer
73. Potential Therapeutic Efficacy of Curcumin in liver cancer
74. Codelivery of doxorubicin and curcumin with lipid nanoparticles results in improved efficacy of chemotherapy in liver cancer
75. Curcumin inhibits MHCC97H liver cancer cells by activating ROS/TLR-4/caspase signaling pathway.
76. Modulation of nuclear factor E2-related factor 2–mediated gene expression in mice liver and small intestine by cancer chemopreventive agent curcumin
77. Synergetic Effect of SLN-Curcumin and LDH-5-Fu on SMMC-7721 liver cancer Cell Line
78. Curcumin Decreases Survival of Hep3B Liver and MCF-7 Breast Cancer Cells
79. Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy
80. Dextran based nanosized carrier for the controlled and targeted delivery of curcumin to liver cancer cells
81. Antiproliferation and apoptosis induced by curcumin in human ovarian cancer cells
82. Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growth
83. Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating akt and p38 mAPK
84. Curcumin enhances Apo2L/TRAIL-induced apoptosis in chemoresistant ovarian cancer cells
85. Curcumin attenuates EGF-induced AQP3 up-regulation and cell migration in human ovarian cancer cells
86. Lysophosphatidic acid induces STAT3 phosphorylation and ovarian cancer cell motility: Their inhibition by curcumin
87. Polymeric Mixed Micelles for Delivery of Curcumin to Multidrug Resistant ovarian cancer
88. Curcumin suppresses constitutive activation of STAT‐3 by up‐regulating protein inhibitor of activated STAT‐3 (PIAS‐3) in ovarian and endometrial cancer cells
89. Curcumin induces apoptosis by inhibiting sarco/endoplasmic reticulum Ca2+ ATPase activity in ovarian cancer cells
90. Polyethylene glycol-phosphatidylethanolamine (PEG-PE)/vitamin E micelles for co-delivery of paclitaxel and curcumin to overcome multi-drug resistance in ovarian cancer
91. Synergism from Sequenced Combinations of Curcumin and Epigallocatechin-3-gallate with Cisplatin in the Killing of Human ovarian cancer Cells
92. The effect of co-delivery of paclitaxel and curcumin by transferrin-targeted PEG-PE-based mixed micelles on resistant ovarian cancer in 3-D spheroids and in vivo tumors
93. Potential Application of Curcumin and Its Analogues in the Treatment Strategy of Patients with Primary Epithelial ovarian cancer
94. Induction of MicroRNA-9 Mediates Cytotoxicity of Curcumin Against SKOV3 ovarian cancer Cells
95. Sphingosine kinase‐1 inhibition sensitizes curcumin‐induced growth inhibition and apoptosis in ovarian cancer cells
96. Polymeric nanoassemblies entrapping curcumin overcome multidrug resistance in ovarian cancer
97. Curcumin suppresses cisplatin resistance development partly via modulating extracellular vesicle-mediated transfer of MEG3 and miR-214 in ovarian cancer
98. B19, a Novel Monocarbonyl Analogue of Curcumin, Induces Human ovarian cancer Cell Apoptosis via Activation of Endoplasmic Reticulum Stress and the Autophagy Signaling Pathway
99. Curcumin sensitizes kidney cancer cells to TRAIL-mediated apoptosis via ROS-JNK- CHOP activation
100. Co-Delivery of Triptolide and Curcumin for ovarian cancer Targeting Therapy via mPEG-DPPE/CaP Nanoparticle
101. Nanostructured lipid carriers enhance the bioavailability and brain cancer inhibitory efficacy of curcumin both in vitro and in vivo
102. Synergistic anti-cancer mechanisms of curcumin and paclitaxel for growth inhibition of human brain tumor stem cells and LN18 and U138MG cells
103. Synthesis of diethylamino-curcumin mimics with substituted triazolyl groups and their sensitization effect of TRAIL against brain cancer cells
104. Curcumin-lipoic acid conjugate as a promising anticancer agent on the surface of gold‑iron oxide nanocomposites: A pH-sensitive targeted drug delivery system for brain cancer theranostics
105. Modulatory Effects of Curcumin and Tyrphostins (AG494 and AG1478) on Growth Regulation and Viability of LN229 Human Brain Cancer Cells
106. The TRAIL Sensitization Effect of Substituted Triazolyl Curcumin Mimics Against Brain Cancer Cells
107. Curcumin may be a new ally in fighting brain cancer
108. Strategies Involving the Food-Derived Agent Curcumin to Eliminate Brain Cancer
109. Targeting human brain cancer stem cells by curcumin-loaded nanoparticles grafted with anti-aldehyde dehydrogenase and sialic acid: Colocalization of ALDH and CD44
110. Curcumin, both Histone Deacetylase and p300/CBP‐Specific Inhibitor, Represses the Activity of Nuclear Factor Kappa B and Notch 1 in Raji Cells
111. Protective effect of curcumin in cisplatin-induced oxidative injury in rat testis: mitogen-activated protein kinase and nuclear factor-kappa B signaling pathways
112. Curcumin inhibits metastatic progression of breast cancer cell through suppression of urokinase-type plasminogen activator by NF-kappa B signaling pathways
113. Curcumin Inhibits Cell Migration of Human Colon Cancer Colo 205 Cells through the Inhibition of Nuclear Factor kappa B /p65 and Down-regulates Cyclooxygenase-2 and Matrix Metalloproteinase-2 Expressions
114. Ameliorative effects of curcumin against renal injuries mediated by inducible nitric oxide synthase and nuclear factor kappa B during gentamicin-induced toxicity in Wistar rats
115. Liposome-encapsulated curcumin suppresses neuroblastoma growth through nuclear factor-kappa B inhibition
116. Hydrogel based oil encapsulation for controlled release of curcumin by using a ternary system of chitosan, kappa-carrageenan, and carboxymethylcellulose sodium salt
117. Curcumin prevents shock-wave lithotripsy-induced renal injury through inhibition of nuclear factor kappa-B and inducible nitric oxide synthase activity in rats
118. The effect of the NF-kappa B inhibitors curcumin and lactacystin on myogenic differentiation of rhabdomyosarcoma cells
119. Curcumin attenuates IL-1β-induced endothelial lipase expression via blocking NF-κB pathway
120. Curcumin ameliorates Ethanol induced Gastric Mucosal Erosion in Rats via alleviation of Oxidative Stress andRegulation of Pro-Inflammatory Cytokines and NF-kappa B activation
121. Curcumin inhibits the invasion of thyroid cancer cells via down-regulation of PI3K/Akt signaling pathway
122. Curcumin inhibits invasion and metastasis in K1 papillary thyroid cancer cells
123. The mechanism underlying proliferation-inhibitory and apoptosis-inducing effects of curcumin on papillary thyroid cancer cells
124. Curcumin inhibits the metastasis of K1 papillary thyroid cancer cells via modulating E-cadherin and matrix metalloproteinase-9 expression
125. Curcumin inhibits hypoxia-induced migration in K1 papillary thyroid cancer cells
126. Combinatorial anticancer effects of curcumin and sorafenib towards thyroid cancer cells via PI3K/Akt and ERK pathways
127. Effects of different extracts of curcumin on TPC1 papillary thyroid cancer cell line
128. Radiosensitive effect of curcumin on thyroid cancer cell death induced by radioiodine-131
129. EF24 (a Curcumin Analog) and ZSTK474 Emphasize the Effect of Cabozantinib in Medullary Thyroid Cancer
130. Curcumin enhances the radiosensitivity of thyroid cancer cells TPC-1
131. Inhibition of Cancer Stem-Like Phenotype by Curcumin and Deguelin in CAL-62 Anaplastic Thyroid Cancer Cells.
132. Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells
133. Curcumin reverses the epithelial-mesenchymal transition of pancreatic cancer cells by inhibiting the Hedgehog signaling pathway
134. Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β‐catenin and Sonic Hedgehog Pathways
135. Curcumin regulates cell fate and metabolism by inhibiting hedgehog signaling in hepatic stellate cells
136. Curcumin inhibits hypoxia-induced epithelial‑mesenchymal transition in pancreatic cancer cells via suppression of the hedgehog signaling pathway
137. Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway
138. Sonic hedgehog and Wnt/β-catenin pathways mediate curcumin inhibition of breast cancer stem cells
139. Curcumin increases efficiency of γ-irradiation in gliomas by inhibiting Hedgehog signaling pathway
140. Arsenic trioxide and curcumin attenuate cisplatin-induced renal fibrosis in rats through targeting Hedgehog signaling

Cycloastragenol

1. Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types
2. Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation
3. Pharmacokinetics, metabolism, and excretion of cycloastragenol, a potent telomerase activator in rats
4. THE EFFECT OF CYCLOASTRAGENOL ON PROLIFERATION OF NEURAL STEM CELLS TREATED WITH OGD
5. Astragaloside VI and cycloastragenol-6-O-beta-D-glucoside promote wound healing in vitro and in vivo
6. Cycloastragenol extends T cell proliferation by increasing telomerase activity (90.30)
7. Research progress of the preparation technology and pharmacological effect of cycloastragenol
8. In vitro intestinal absorption and first-pass intestinal and hepatic metabolism of cycloastragenol, a potent small molecule telomerase activator
9. Cycloastragenol improves hepatic steatosis by activating farnesoid X receptor signalling
10. Effect of continuous oral cycloastragenol on the activity of cytochrome P450 enzymes in rats
11. Characterization of Cycloartane-Type Sapogenol Derivatives for Prostate Cancer Chemoprevention
12. Cycloartane-type sapogenol derivatives inhibit NFκB activation as chemopreventive strategy for inflammation-induced prostate carcinogenesis
13. Cycloastragenol(Telomeres Activator) and its relation with Cancer: A Brief Review
14. Semi-synthesis of Cytotoxic Molecules From Cycloartane Type Sapogenols cyctotoxicities were tested against three different cancer cell lines (HT-29: human column cancer cell line; MDA-MB-231: human breast cancer cell line; PC-3: human prostate cancer cell line)
15. Pharmaceutical regulation of telomerase and its clinical potential This inhibitor has been applied to breast cancers [40, 41], prostate cancers [42], glioblastoma [43], myeloma [leukemia.”>44] and leukaemia [39].
16. Cycloastragenol can negate constitutive STAT3 activation and promote paclitaxel-induced apoptosis in human gastric cancer cells
17. Astragaloside attenuates the progression of prostate cancer cells through endoplasmic reticulum stress pathways Cycloastragenol and As IV, which are active ingredients of Astragalus membranaceus, were revealed to have almost equal efficiency in inhibiting ROS-associated ER stress
18. A role of telomerase in cancer progression and therapeutic program for anti-telomerase approachand future objectives telomerase activity might be a useful marker for diagnosis and monitoring (detect stage of cancer and outcome of disease) in different cancers includingprostate, bladder,thyroid, breast, colon, gastric and lung
19. Cycloastragenol suppressed the fat accumulation through regulating the Hedgehog signaling in high fat diet-induced obesity animal model

Cynara cardunculus

1. Inhibitory effect of the flowers of artichoke (Cynara cardunculus) on TPA-induced inflammation and tumor promotion in two-stage carcinogenesis
2. Growth inhibitory effect of ethyl acetate‐soluble fraction of Cynara cardunculus L. in leukemia cells involves cell cycle arrest, cytochrome c release and activation
3. Antioxidative Properties of Cardoon (Cynara cardunculus L.) Infusion Against Superoxide Radical, Hydroxyl Radical, and Hypochlorous Acid
4. Effect of salinity on growth, leaf-phenolic content and antioxidant scavenging activity in Cynara cardunculus L.
5. In vitro investigation of cytotoxic and apoptotic effects of Cynara L. species in colorectal cancer cells
6. Inhibition of Pro-inflammatory Secreted Phospholipase A2 by Extracts from Cynara cardunculus L.
7. Antigenotoxic effect of extract from Cynara cardunculus L.
8. Biological characterization of Cynara cardunculus L. methanolic extracts: antioxidant, anti-proliferative, anti-migratory and anti-angiogenic activities
9. Antiproliferative effects of Cynara cardunculus L. var. altilis (DC) Lipophilic extracts
10. Antinociceptive and anti-inflammatory effects of novel dietary protein hydrolysate produced from whey by proteases of Cynara cardunculus
11. Antiproliferative Effects of Cynara cardunculus L. var. altilis (DC) Lipophilic Extracts
12. Effect of Cynara extracts on multiple myeloma cell lines
13. Cynara cardunculus ssp. cardunculus on C32 and ACHN cell lines with IC₅₀ of 21 and 18 μg/ml, respectively. Mentha aquatica showed a selective antiproliferative activity on breast cancer while significant activity
14. Effect of Cynara extracts on multiple myeloma cell lines Cancer is the main cause of death in the world. Breast, prostate, colon cancer are the most common types of neoplasia.
15. Medicinal Plants Combating Against Cancer – a Green Anticancer Approach Vinblastine and vincristine are primarily used in combination with other cancer chemotherapeutic drugs for the treatment of different types of cancers, including leukemias, lymphomas, testicular cancer, breast and lung cancers, and Kaposi’s sarcoma
16. Biological Characterization of Cynara cardunculus L. Methanolic Extracts: Antioxidant, Anti-proliferative, Anti-migratory and Anti-angiogenic Activities Different methanolic extracts obtained from wild and cultivated plants were tested for antioxidant activity and effect on breast tumor cell viability.
17. Cynara cardunculus L. has evidenced anticancer potential on triple-negative breast cancer (TNBC). T
18. EFFECT OF HYDROALCOHOLIC CYNARA SCOLYMUS L. EXTRACT ON INJURED PANCREATIC TISSUE IN DIABETIC RATS
19. Growth inhibitory effect of ethyl acetate‐soluble fraction of Cynara cardunculus L. in leukemia cells involves cell cycle arrest, cytochrome c release and activation of caspases
20. Biochemical and chemical characterization of Cynara cardunculus L. extract and its potential use as co-adjuvant therapy of chronic myeloid leukemia

Dalbergia odorifera

1. 4, 2′, 5′-Trihydroxy-4′-methoxychalcone from Dalbergia odorifera exhibits anti-inflammatory properties by inducing heme oxygenase-1 in murine macrophages
2. Antitumor components isolated from the heartwood extract of Dalbergia odorifera
3. Physicochemical Properties, Chemical Composition and Antioxidant Activity of Dalbergia odorifera T. Chen Seed Oil
4. Antioxidant activities of compounds isolated from Dalbergia odorifera T. Chen and their inhibition effects on the decrease of glutathione level of rat lens induced by UV
5. Isoliquiritigenin, from Dalbergia odorifera, up-regulates anti-inflammatory heme oxygenase-1 expression in RAW264. 7 macrophages
6. Inhibitory constituents of the heartwood of Dalbergia odorifera on nitric oxide production in RAW 264.7 macrophages
7. Identification and determination of major flavonoids in rat serum by HPLC–UV and HPLC–MS methods following oral administration of Dalbergia odorifera extract
8. Antioxidant properties of butein isolated from Dalbergia odorifera
9. Antioxidant activities of natural phenolic components from Dalbergia odorifera T. Chen
10. Butein sensitizes human leukemia cells to apoptosis induced by tumor necrosis factor-related apoptosis inducing ligand (TRAIL)
11. Dalbergia odorifera extract promotes angiogenesis through upregulation of VEGFRs and PI3K/MAPK signaling pathways
12. New Cinnamylphenols from Dalbergia Species with Cancer Chemopreventive Activity
13. Antitumor Components Isolated from the Heartwood Extract of Dalbergia odorifera
14. Isolation of antitumor agent from the heartwood of Dalbergia odorifera
15. The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase
16. Butein suppresses breast cancer growth by reducing a production of intracellular reactive oxygen species
17. Butein suppresses cervical cancer growth through the PI3K/AKT/mTOR pathway
18. Potential of butein, a tetrahydroxychalcone to obliterate cancer It also inhibits tumor angiogenesis, invasion and metastasis in prostate, liver and bladder cancers through the inhibition of MMPs, VEGF etc.
19. Butein Shows Cytotoxic Effects and Induces Apoptosis in Human ovarian cancer Cells
20. A Study on Ethanolic Extract of Dalbergia sissoo roxb. Leaves for Pancreatic Lipase Inhibition

EGCG

1. Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway
2. Green tea epigallocatechin gallate shows a pronounced growth inhibitory effect on cancerous cells but not on their normal counterparts
3. Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical lesions
4. Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications
5. Multifunctional effect of epigallocatechin-3-gallate (EGCG) in downregulation of gelatinase-A (MMP-2) in human breast cancer cell line MCF-7
6. EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells.
7. Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines
8. Role of epigallocatechin gallate (EGCG) in the treatment of breast and prostate cancer
9. A Major Constituent of Green Tea, EGCG, Inhibits the Growth of a Human Cervical Cancer Cell Line
10. Epigallocatechin Gallate (EGCG) is the most effective cancer chemopreventive polyphenol in green tea
11. Pre-clinical evaluation of prostate specific membrane antigen (PSMA) nanobioconjugate encapsulating green tea polyphenol EGCG for prostate cancer
12. Green tea polyphenol EGCG blunts androgen receptor function in prostate cancer
13. Laminin receptor specific therapeutic gold nanoparticles (198AuNP-EGCg) show efficacy in treating prostate cancer
14. The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition
15. Epigallocatechin-3-gallate (EGCG) inhibits PC-3 prostate cancer cell proliferation via MEK-independent ERK1/2 activation
16. Oral administration of naturally occurring chitosan-based nanoformulated green tea polyphenol EGCG effectively inhibits prostate cancer cell growth in a xenograft model
17. Suppression of Wnt Signaling by the Green Tea Compound (–)-Epigallocatechin 3-Gallate (EGCG) in Invasive Breast Cancer Cells
18. Suppression of cell proliferation and gene expression by combinatorial synergy of EGCG, resveratrol and γ-tocotrienol in estrogen receptor-positive MCF-7 breast cancer cells
19. EGCG down-regulates telomerase in human breast carcinoma MCF-7 cells, leading to suppression of cell viability and induction of apoptosis
20. Epigallocatechin-3-Gallate (EGCG) Inhibits Cell Proliferation and Migratory Behaviour of Triple Negative Breast Cancer Cells
21. Epigallocatechin-3-gallate (EGCG) downregulates gelatinase-B (MMP-9) by involvement of FAK/ERK/NFκB and AP-1 in the human breast cancer cell line MDA-MB-231
22. EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer
23. EGCG Enhances the Therapeutic Potential of Gemcitabine and CP690550 by Inhibiting STAT3 Signaling Pathway in Human pancreatic cancer
24. PDE3 inhibitor and EGCG combination treatment suppress cancer stem cell properties in pancreatic ductal adenocarcinoma
25. Copolymeric Micelles for Delivery of EGCG and Cyclopamine to pancreatic cancer Cells
26. Abstract 2868: EGCG inhibits pancreatic cancer growth in xenografts and KrasG12D transgenic mice models
27. Abstract #3919: EGCG inhibits Hsp90 function by impairing Hsp90 association with cochaperones in pancreatic cancer cells
28. Abstract 859: EGCG inhibits pancreatic cancer growth and stem cell characteristics in xenografts and KrasG12D transgenic mice models
29. Abstract 200: EGCG inhibits pancreatic cancer stem cell characteristics in human primary tumors, and carcinogenesis in KrasG12D transgenic mice.
30. Abstract 171: EGCG enhances the therapeutic potential of gemcitabine and CP690550 (Tasocitinib) by inhibiting STAT3 signaling pathway in human pancreatic cancer cells
31. Effect of EGCG in combination with gemcitabine on β-catenin expression in PANC-1 human pancreatic cancer cells
32. EGCG, An Active Ingredient in Green Tea, Modulates Cell Proliferation in Human pancreatic cancer Cells and Rat Osteosarcoma Cells in vitro
33. The Effect of (−)-Epigallocatechin-3-gallate (EGCG) on Cell Viability and Protein Expression in Human pancreatic cancer Cells (Panc-1) and Rat Osteosarcoma Cell Cultures (UMR 106-01 BSP)
34. Epigallocatechin-3-Gallate (EGCG) Suppresses pancreatic cancer Cell Growth, Invasion, and Migration partly through the Inhibition of Akt Pathway and Epithelial–Mesenchymal Transition: Enhanced Efficacy When Combined with Gemcitabine
35. Inhibitory Effects of the Combination of (-)-epigallocatechin-3-gallate (EGCG) and Pterostilbene on pancreatic cancer Growth in Vitro
36. VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia
37. Inhibition of HuR and MMP-9 expression in macrophage-differentiated HL-60 myeloid leukemia cells by green tea polyphenol EGCg
38. Anti-proliferative and differentiation-inducing activities of the green tea catechin epigallocatechin-3-gallate (EGCG) on the human eosinophilic leukemia EoL-1 cell line
39. Green tea polyphenol EGCG causes anti-cancerous epigenetic modulations in acute promyelocytic leukemia cells
40. EGCG targeting efficacy of NF-κB downstream gene products is dictated by the monocytic/macrophagic differentiation status of promyelocytic leukemia cells
41. Epigallocatechin Gallate (EGCG), Influences a Murine WEHI-3 leukemia Model In Vivo Through Enhancing Phagocytosis of Macrophages and Populations of T- and B-Cells
42. Difference in growth suppression and apoptosis induction of EGCG and EGC on human promyelocytic leukemia HL-60 cells
43. Effect of Epigallocatechin-3-gallate (EGCG) on cell proliferation inhibition and apoptosis induction in lymphoblastic leukemia cell line
44. Gene expression spectra in human leukemia HL-60 cells treated with EGCG
45. Biological significance of myeloperoxidase (MPO) on green tea component, (−)-epigallocatechin-3-gallate (EGCG)-induced apoptosis: its therapeutic potential for myeloid leukemia
46. Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1α
47. NEAT1 upregulates EGCG-induced CTR1 to enhance cisplatin sensitivity in lung cancer cells
48. The Green Tea Polyphenol EGCG Potentiates the Antiproliferative Activity of c-Met and Epidermal Growth Factor Receptor Inhibitors in Non–small Cell lung cancer Cells
49. TGF-β1-induced epithelial–mesenchymal transition and acetylation of Smad2 and Smad3 are negatively regulated by EGCG in Human A549 lung cancer cells
50. Gene regulation mediated by microRNAs in response to green tea polyphenol EGCG in mouse lung cancer
51. EGCG Inhibits Transforming Growth Factor-β-Mediated Epithelial-to-Mesenchymal Transition via the Inhibition of Smad2 and Erk1/2 Signaling Pathways in Nonsmall Cell lung cancer Cells
52. EGCG Inhibits the Invasion of Highly Invasive CL1-5 lung cancer Cells through Suppressing MMP-2 Expression via JNK Signaling and Induces G2/M Arrest
53. A prospective phase II trial of EGCG in treatment of acute radiation-induced esophagitis for stage III lung cancer
54. Effects of Epigallocatechin-3-gallate (EGCG) on A549 lung cancer Tumor Growth and Angiogenesis
55. Combination of Low Concentration of (−)-Epigallocatechin Gallate (EGCG) and Curcumin Strongly Suppresses the Growth of Non-Small Cell lung cancer in Vitro and in Vivo through Causing Cell Cycle Arrest
56. Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway
57. EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells
58. A comparison of 5-fluorouracil and natural chemotherapeutic agents, EGCG and thymoquinone, delivered by sustained drug delivery on colon cancer cells.
59. Implication of Akt, ERK1/2 and alternative p38MAPK signalling pathways in human colon cancer cell apoptosis induced by green tea EGCG
60. Reduction in promotor methylation utilizing EGCG (epigallocatechin-3-gallate) restores RXRα expression in human colon cancer cells
61. Apoptotic Effects of Curcumin and EGCG via Akt-p53 Signaling Pathway in HCT116 colon cancer Cell
62. Control of AMP-activated protein kinase, Akt, and mTOR in EGCG-treated HT-29 colon cancer cells
63. Differences in the Effects of EGCG on Chromosomal Stability and Cell Growth between Normal and colon cancer Cells
64. EGCG and Polyphenon E inhibit growth and activation of EGFR and HER2 signaling pathways in human colon cancer cells
65. Sa1956 Multiple Dosing Regimens With (-)-Epigallocatechin-Gallate (EGCG) Dramatically Reduce Tumor Burden in a Murine Model of Inflammation Induced colon cancer
66. EGCG synergizes the therapeutic effect of cisplatin and oxaliplatin through autophagic pathway in human colorectal cancer cells
67. (−)-Epigallocatechin-3-Gallate (EGCG) Post-transcriptionally and Post-translationally Suppresses the Cell Proliferative Protein TROP2 in Human colorectal cancer Cells
68. Green tea catechin EGCG suppresses NUDT6 (nudix [nucleoside diphosphate linked moiety X]-type motif 6) expression in human colorectal cancer
69. (−)-Epigallocatechin Gallate (EGCG) Enhances the Sensitivity of colorectal cancer Cells to 5-FU by Inhibiting GRP78/NF-κB/miR-155-5p/MDR1 Pathway
70. Sa1953 Epigallocatechin-3-Gallate (EGCG) Targets Cancer Stem-Like Cells and Enhances 5-Fluorouracil Chemosensitivity in Chemoresistant colorectal cancer
71. Binding affinity analysis and ADMET prediction of epigallocatechine gallate (EGCG) derivatives for AP-1 protein: a drug target for liver cancer
72. Chemoprevention of elite tea variety CFT‐1 rich in EGCG against chemically induced liver cancer in rats
73. A two-stage, single-arm, phase II study of EGCG-enriched green tea drink as a maintenance therapy in women with advanced stage ovarian cancer
74. Pathophysiological Responses Associated with Exposure to TQ and EGCG Using CAOV-3 ovarian cancer Like Cells.
75. Changes of cell cycle regulatory proteins expression by EGCGin ovarian cancer cells
76. Bioinformatics analysis on molecular mechanism of active compound of green tea(EGCG) in treatment of ovarian cancer
77. Abstract 5610: Epigallocatechin 3-gallate (EGCG) as a natural product (NP) with potent antitumor activity against human ovarian cancer
78. Effect of EGCG on Methylation and Expression of RASSF1A in ovarian cancer Cell Line A2780
79. “Suppression of the Progressive Behavior of ovarian cancer like Cells using Thymoquinone (TQ) and Epigallocatechin-3-gallate (EGCG) in vitro”
80. Green tea epigallocatechin‐3‐gallate (EGCG) promotes neural progenitor cell proliferation and sonic hedgehog pathway activation during adult hippocampal neurogenesis
81. Mechanism study of EGCG on proliferation of human MGC-803 cell through Hedgehog pathway
82. EGCG通过Hedgehog信号抑制人胃癌MGC-803细胞增殖的机制研究

Eleutherococcus senticosus

1. Proliferative and inhibitory activity of siberian ginseng (eleutherococcus senticosus) extract on cancer cell lines; A-549, XWLC-05, HCT-116, CNE and Beas-2b
2. Eleutherococcus senticosus (Rupr. & Maxim.) Maxim.(Araliaceae) as an adaptogen: a closer look
3. Flow-cytometric studies with eleutherococcus senticosus extract as an immunomodulatory agent.
4. Immunopharmacological in vitro effects of Eleutherococcus senticosus extracts
5. Anti-metastatic activity of Acanthopanax senticosus extract and its possible immunological mechanism of action
6. Effect of temperature on secondary metabolites production and antioxidant enzyme activities in Eleutherococcus senticosus somatic embryos
7. Eleutherococcus senticosus extract attenuates LPS-induced iNOS expression through the inhibition of Akt and JNK pathways in murine macrophage
8. The inhibiting effect of phytoadaptogenic preparations from bioginseng, Eleutherococcus senticosus and Rhaponticum carthamoides on the development of nervous
9. Intraspecific relationship analysis by DNA markers and in vitro cytotoxic and antioxidant activity in Eleutherococcus senticosus
10. Preventive effects of Eleutherococcus senticosus bark extract in OVX-induced osteoporosis in rats
11. Eleutherococcus senticosus in human cancer cells
12. Proliferative and Inhibitory Activity of Siberian ginseng (Eleutherococcus senticosus) Extract on Cancer Cell Lines; A-549, XWLC-05, HCT-116, CNE and Beas-2b
13. Siberian Ginseng (Eleutherococcus Senticosus) Against Dog Cancer
14. Suppression of growth and invasive behavior of human prostate cancer cells by ProstaCaidTM: Mechanism of activity
15. ProstaCaid™ inhibits tumor growth in a xenograft model of human prostate cancer
16. Holistic Approaches to Prostate Cancer
17. ProstaCaid Induces G2/M Cell Cycle Arrest and Apoptosis in Human and Mouse Androgen-Dependent and-Independent Prostate Cancer Cells
18. Cytotoxic Effects of Eleutherococcus senticosus Aqueous Extracts in Combination with N6(Δ2-Isopentenyl)-adenosine and 1-β-D-Arabinofuranosylcytosine Against L1210 leukemia Cells
19. Cytotoxic activity of ethanolic extracts of Eleutherococcus species cultivated in Poland on HL60 leukemia cell line

Emblica officinalis

1. Emblica officinalis: effects on in vitro cell growth of human tumor cell lines
2. Amla (Emblica officinalis Gaertn), a wonder berry in the treatment and prevention of cancer
3. Antitumour activity of Emblica officinalis
4. Antitumour effects of Phyllanthus emblica L.: induction of cancer cell apoptosis and inhibition of in vivo tumour promotion and in vitro invasion of human cancer cells
5. Antioxidant activity of Emblica officinalis
6. Emblica officinalis extract induces autophagy and inhibits human ovarian cancer cell proliferation, angiogenesis, growth of mouse xenograft tumors
7. Protective effect of an extract of Emblica officinalis against radiation-induced damage in mice
8. Pyrogallol, an active compound from the medicinal plant Emblica officinalis, regulates expression of pro-inflammatory genes in bronchial epithelial cells
9. Free and bound phenolic antioxidants in amla (Emblica officinalis) and turmeric (Curcuma longa)
10. Ameliorative effect of Emblica officinalis aqueous extract on ochratoxin-induced lipid peroxidation in the kidney and liver of mice
11. Emblica officinalis Gaertn.) suppresses cell proliferation and induces apoptosis in human colon cancer
12. The effects of Emblica officinalis and Tinospora cordifolia herbal treatment on the prognosis of squamous cell carcinoma of the buccal mucosa and tongue
13. Emblica officinalis extract downregulates pro-angiogenic molecules via upregulation of cellular and exosomal miR-375 in human ovarian cancer cells
14. Anticancer and cell cycle analysis of aqueous extract of fruits on Emblica officinalis human colorectal and neuroblastoma cancer cell lines
15. Protective effect of a polyherbal preparation, Brahma rasayana against tumor growth and lung metastasis in rat prostate model system.
16. anti-cancerous activity of E. officinalis that contains ellagic acid, gallic acid, quercetin, kaempferol, emblicannin etc. whereby ellagic acid has good anti-cancerous properties which successfully inhibited the breast and uterus cancers
17. Synergistic growth inhibitory effects of Phyllanthus emblica and Terminalia bellerica extracts with conventional cytotoxic agents: Doxorubicin and cisplatin against human hepatocellular carcinoma and lung cancer cells
18. From Ancient Medicine to Modern Medicine: AyurvedicConcepts of Health and Their Role in Inflammation andCancer
19. Effects of extracts from Bangladeshi medicinal plants on in vitro proliferation of human breast cancer cell lines and expression of estrogen receptor α gene
20. Vitamin C content and antioxidant activity of the fruit and of the Ayurvedic preparation of Emblica officinalis Gaertn.
21. Immunomodulatory and anticancer activities of phenolics from emblica fruit (Phyllanthus emblica L.)
22. Emblica officinalis Geart.: A Comprehensive Review on Phytochemistry, Pharmacology and Ethnomedicinal Uses E. officinalis also showed antiproliferative activity on MCF7 and MDA-MB-231 breast cancer cell lines
23. Anticancer and cell cycle analysis of aqueous extract offruits onEmblica officinalishuman colorectal and neuroblastoma cancer cell lines

Epimedium koreanum

1. Estrogenic/antiestrogenic activities of a Epimedium koreanum extract and its major components: in vitro and in vivo studies
2. Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1α in human osteosarcoma cells
3. Combined Treatment with Epimedium koreanum Nakai Extract and Gefitinib Overcomes Drug Resistance Caused by T790M Mutation in Non-Small Cell Lung Cancer
4. An integrated plasma and urinary metabonomic study using UHPLC–MS: Intervention effects of Epimedium koreanum on ‘Kidney-Yang Deficiency syndrome’rats
5. 2-Phenoxychromones and Prenylflavonoids from Epimedium koreanum and Their Inhibitory Effects on LPS-Induced Nitric Oxide and Interleukin-1β Production
6. Epimedium koreanum extract and its constituent icariin improve motor dysfunction in spinal cord injury
7. Comparison of antioxidative and antitumor activities of six flavonoids from Epimedium koreanum
8. Effects of Icariside II from Epimedium koreanum on Tumour Cell Lines In‐vitro
9. Epimedium koreanum Nakai displays broad spectrum of antiviral activity in vitro and in vivo by inducing cellular antiviral state
10. Cytotoxic Effects of Flavonol Glycosides and Nonflavonoid Constituents of Epimedium koreanum. on Primary Osteoblasts
11. Epimedium koreanum Nakai inhibits PMA-induced cancer cell migration and invasion by modulating NF-κB/MMP-9 signaling in monomorphic malignant
12. Polysaccharides from Epimedium koreanum Nakai with immunomodulatory activity and inhibitory effect on tumor growth in LLC-bearing mice
13. Inhibitory Effects of the Aerial Parts of Epimedium koreanum on TPA-Induced Inflammation and Tumour Promotion in Two-Stage Carcinogenesis in Mouse Skin
14. Inhibitory Effects of the Aerial Parts of Epimedium koreanum on TPA-Induced Inflammation and Tumour Promotion in Two-Stage Carcinogenesis in Mouse Skin
15. Anti-androgenic activity of icarisid II from Epimedium Herb in prostate cancer LNCaP cells
16. Cyclooxygenase-2/prostaglandin E2 pathway mediates icariside II induced apoptosis in human PC-3 prostate cancer cells
17. Molecular and pharmacodynamic properties of estrogenic extracts from the traditional Chinese medicinal herb, Epimedium
18. In Vitro cytotoxic activity of some Korean medicinal plants on human cancer cell lines: enhancement in cytotoxicity by heat processing. Hormone‐dependent prostate cancer cells (LNCaP).
19. Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer
20. Epimedium koreanum Nakai inhibits PMA-induced cancer cell migration and invasion by modulating NF-κB/MMP-9 signaling in monomorphic malignant human glioma cells
21. Baohuoside I Suppresses Invasion of Cervical and Breast Cancer Cells through the Downregulation of CXCR4 Chemokine Receptor Expression

Euonymus alatus

1. Inhibitory Effects of Scutellaria Barbata D. Don. and Euonymus Alatus Sieb. on Aromatase Activity of Human Leiomyomal Cells
2. Euonymus alatus prevents the hyperglycemia and hyperlipidemia induced by high-fat diet in ICR mice
3. Phenolic constituents from the twigs of Euonymus alatus and their cytotoxic and anti-inflammatory activity
4. Inhibitory effect of methanol extract of Euonymus alatus on matrix metalloproteinase-9
5. A new matrix metalloproteinase-9 inhibitor 3, 4-dihydroxycinnamic acid (caffeic acid) from methanol extract of Euonymus alatus: isolation and structure determination
6. Euonymus alatus (Thunb.) Sieb induces apoptosis via mitochondrial pathway as prooxidant in human uterine leiomyomal smooth muscle cells
7. Inhibitory constituents of Euonymus alatus leaves and twigs on nitric oxide production in BV2 microglia cells
8. Kaempferol and quercetin isolated from Euonymus alatus improve glucose uptake of 3T3-L1 cells without adipogenesis activity
9. Alleviating Effects of Active Fraction of Euonymus alatus Abundant in Flavonoids on Diabetic Mice
10. Inhibitory activity of Euonymus alatus against alpha-glucosidase in vitro and in vivo
11. Euonymus alatus (Thunb.) Sieb induces apoptosis via mitochondrial pathway as prooxidant in human uterine leiomyomal smooth muscle cells.
12. A study of antiproliferative effect by Euonymus alatus (Thunb.) Sieb water-extract on SKBR3 human breast cancer cell line
13. ANTICANCER ACTIVITY OF EUONYMUS EUROPAEUSFRUITS EXTRACT ON HUMAN MELANOMA CELLS
14. A study of antiproliferative effect by Euonymus alatus (Thunb.) Sieb water-extract on SKBR3 human breast cancer cell line
15. Cytotoxic and Antioxidant Compounds Isolated from the Cork of Euonymus alatus Sieb.
16. Screening of Stat3 inhibitory effects of Korean herbal medicines in the A549 human lung cancer cell line the cytotoxic activity of various chemotherapeutic agents in various human cancer cell lines, including colorectal cancer, prostate cancer, and breast cancer;
17. Phytochemicals for breast cancer prevention by targeting aromatasextracts of the herb Scutellaria barata D. Don (SB) and the invasive shrub Euonymus alatus Sieb (EA) were also shown to possess anti-aromatase activity.
18. Altered Protein Expression in Ovarian and Cervical Cancer Cells by the Treatment of Extracts from Euonymus alatus Sieb, Oldenlandia diffusa (Willd.) Roxburgh, and Orostachys japonicus A. Berger

Flammulina velutipes (enokitake)

1. The isolation and characterization of an immunomodulatory and anti-tumor polysaccharide preparation from Flammulina velutipes
2. Purification, characterization and biological activity on hepatocytes of a polysaccharide from Flammulina velutipes mycelium
3. Effect of Flammulina velutipes polysaccharides on production of cytokines by murine immunocytes and serum levels of cytokines in tumor-bearing mice
4. INTENSIFICATION OF ANTITUMOR-IMMUNITY BY PROTEINBOUND POLYSACCHARIDE, EA6, DERIVED FROM FLAMMULINA VELUTIPES
5. Immunomodulating and anti-tumor action of extracts of several mushrooms
6. Interruption of lung cancer cell migration and proliferation by fungal immunomodulatory protein FIP-fve from Flammulina velutipes
7. Purification, characterization and anti-proliferation activity of polysaccharides from Flammulina velutipes
8. Anti-tumor mechanisms of orally administered a fungal immunomodulatory protein from Flammulina velutipes in mice
9. Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides
10. Enokitake, Flammulina velutipes: Host‐mediated antitumor polysaccharides
11. Flammulina velutipes (Agaricomycetes), Capable of Enhancing Natural Killer Cell Activity against K562 Tumor
12. Mushrooms and the prevention and treatment of Cancer
13. Investigating the effect of N-terminal methionine addition, hydrophobic interaction enhancement and loop modification in modifying immunomodulatory and cancer-inhibitory activities of FIP-fve mutants Mutations of loop DE and hinge residue E61K were crucial in directing immune response towards T helper 1 (TH1) and displayed significant inhibition towards breast cancer MDA-MB-231 cell viability
14. TREATEMNET OF CANCER BY MEDICINAL MUSHROOMS Agaricus bisporus shows inhibition of breast cancer development. Similarly other species like Lentinula edodes, Hericum erinaceus Flammulina velutipes shows effect.
15. Cancer Killing Medicinal Mushrooms
16. Interruption of lung cancer Cell Migration and Proliferation by Fungal Immunomodulatory Protein FIP-fve from Flammulina velutipes
17. INTENSIFICATION OF ANTITUMOR-IMMUNITY BY PROTEINBOUND POLYSACCHARIDE, EA6, DERIVED FROM FLAMMULINA VELUTIPES (CURT.ex FR.) SING. COMBINED WITH MURINE leukemia L1210 VACCINE IN ANIMAL EXPERIMENTS

Frankincense (Boswellia carteri)

1. Cancer chemopreventive effects and cytotoxic activities of the triterpene acids from the resin of Boswellia carteri
2. Frankincense oil derived from Boswellia carteri induces tumor cell specific cytotoxicity
3. Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human breast cancer cells
4. Effect of Boswellia thurifera gum methanol extract on cytotoxicity and P53 gene expression in human breast cancer cell line
5. Frankincense essential oil prepared from hydrodistillation of Boswellia sacra gum resins induces human pancreatic cancer cell death in cultures
6. Differential effects of selective frankincense (Ru Xiang) essential oil versus non-selective sandalwood (Tan Xiang) essential oil on cultured bladder cancer
7. Review on anti-tumor effect of triterpene acid compounds
8. Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri
9. Major constituents of Boswellia carteri resin exhibit cyclooxygenase enzyme inhibition and antiproliferative activity.
10. Beckmann rearrangement products of methyl 3-oxo-tirucall-8, 24-dien-21-oate from Boswellia serrata gum and their anti-tumor activity
11. Management of basal cell carcinoma of the skin using frankincense (Boswellia sacra) essential oil: a case report Acetyl-11-keto-b-boswellic acid inhibits prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis.
12. Extraction of biologically active compounds by hydrodistillation of Boswelliaspecies gum resins for anti-cancer therapy
13. The potential role of boswellic acids in cancer prevention and treatment
14. 5α‐androstane‐3α,17β‐diol supports human prostate cancer cell survival and proliferation through androgen receptor‐independent signaling pathways: Implication of androgen‐independent prostate cancer progression
15. Triterpenoids for Cancer Prevention and Treatment: Current Status and Future Prospects In this review, we have highlighted several studies on chemopreventive and anticancer potential of triterpenoids based on various preclinical animal models of colon, breast, prostate, and melanoma cancers.
16. Design and synthesis of novel 2-substituted 11-keto-boswellic acid heterocyclic derivatives as anti-prostate cancer agents with Pin1 inhibition ability
17. Methanolic extract of Boswellia serrata exhibits anti-cancer activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells
18. Effect of frankincense extract on VEGF and its receptor-1 expression in acute promyelocytic leukemia cell lines HL-60 cells
19. INDUCED DIFFERENTIATION OF FRANKINCENSE EXTRACT ON CELLS WITH ACUTE NON-LYMPHATIC leukemia
20. Impact of consuming Boswellia carteri oleo-gumresinswater extracton colon cancerinducedin rats
21. A Pre-Clinical Investigation of the Anti-Cancer Effects of the Frankincense Constituent AKBA on ovarian cancer Cells

Fucus vesiculosus (seaweed)

1. Fucoidan from Sargassum sp. and Fucus vesiculosus reduces cell viability of lung carcinoma and melanoma cells in vitro and activates natural killer cells
2. Fucoidan from seaweed Fucus vesiculosus inhibits migration and invasion of human lung cancer cell via PI3K-Akt-mTOR pathways
3. In vitro chemopreventive potential of fucophlorethols from the brown alga Fucus vesiculosus L. by anti-oxidant activity
4. Brown seaweed fucoidan: biological activity and apoptosis, growth signaling mechanism in cancer
5. Fucoidan as a marine anticancer agent in preclinical development
6. Fucoidan and cancer: a multifunctional molecule with anti-tumor potential
7. Anticancer effects of different seaweeds on human colon and breast cancers
8. Antioxidant capacities of phlorotannins extracted from the brown algae Fucus vesiculosus
9. Fucoidan, a major component of brown seaweed, prohibits the growth of human cancer cell lines in vitro
10. The anticancer effect of fucoidan in PC-3 prostate cancer cells
11. Structure and antitumour activity of fucoidan isolated from sporophyll of Korean brown seaweed Undaria pinnatifida
12. Seaweed Prevents Breast Cancer?
13. The dietary intake of laminaria, a brown seaweed, and breast cancer prevention
14. The consumption of seaweed as a protective factor in the etiology of breast cancer
15. A case–control study on seaweed consumption and the risk of breast cancer
16. Polyphenol-rich seaweed (Eucheuma cottonii) extract suppresses breast tumour via hormone modulation and apoptosis induction
17. Fucoidan from Seaweed Fucus vesiculosus Inhibits Migration and Invasion of Human lung cancer Cell via PI3K-Akt-mTOR Pathways

Gambogic acid (Garcinia hanburyi)

1. Anticancer effect and apoptosis induction of gambogic acid in human gastric cancer line BGC-823
2. Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling
3. Gambogic acid induces apoptosis and regulates expressions of Bax and Bcl-2 protein in human gastric carcinoma MGC-803 cells
4. Anti-invasive effect of gambogic acid in MDA-MB-231 human breast carcinoma cells
5. Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytes
6. Poloxamer 407/TPGS mixed micelles for delivery of gambogic acid to breast and multidrug-resistant cancer
7. Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells
8. Involvement of matrix metalloproteinase 2 and 9 in gambogic acid induced suppression of MDA-MB-435 human breast carcinoma cell lung metastasis
9. Gambogic acid inhibits tumor cell adhesion by suppressing integrin β1 and membrane lipid rafts-associated integrin signaling pathway
10. Gambogic acid inhibits TNF-α-induced invasion of human prostate cancer PC3 cells in vitro through PI3K/Akt and NF-κB signaling pathways
11. Therapeutic potential of gambogic acid, a caged xanthone, to target cancer
12. Gambogenic Acid Induction of Apoptosis in a Breast Cancer Cell Line
13. Recent Research on Bioactive Xanthones from Natural Medicine: Garcinia hanburyi Gambogic acid dramatically inhibited the lung metastases and xenograft tumor growth in athymic BALB/c nude mice infecting MDA-MB-231 human breast carcinoma cells.
14. Microtubule depolymerization and phosphorylation of c-Jun N-terminal kinase-1 and p38 were involved in gambogic acid induced cell cycle arrest and apoptosis in human breast carcinoma MCF-7 cells
15. Gambogic Acid is a Novel Anti-cancer Agent that Inhibits Cell Proliferation, Angiogenesis and Metastasis
16. Xanthones with Antiproliferative Effects on Prostate Cancer Cells from the Stem Bark of Garcinia
17. Gambogic acid inhibits thioredoxin activity and induces ROS-mediated cell death in castration-resistant prostate cancer
18. Antiproliferative activities of Garcinia bracteata extract and its active ingredient, isobractatin, against human tumor cell lines
19. Gambogic acid, a potent inhibitor of survivin, reverses docetaxel resistance in gastric cancer cells
20. Gambogic Acid Induces Apoptosis in Imatinib-Resistant Chronic Myeloid leukemia Cells via Inducing Proteasome Inhibition and Caspase-Dependent Bcr-Abl Downregulation
21. Gambogic acid induces G0/G1 arrest and apoptosis involving inhibition of SRC-3 and inactivation of Akt pathway in K562 leukemia cells
22. Caspase-8 preferentially senses the apoptosis-inducing action of NG-18, A gambogic acid derivative, in human leukemia HL-60 cells
23. Synergistic effect of magnetic nanoparticles of Fe3O4 with gambogic acid on apoptosis of K562 leukemia cells
24. Anticancer Effect and Apoptosis Induction of Gambogic Acid in Human leukemia Cell Line K562 In Vitro
25. Effects of magnetic nanoparticle of Fe3O4 on apoptosis induced by Gambogic acid in U937 leukemia cells.
26. Gambogic Acid Combined With CdTe QDs For leukemia Cancer Cells Inhibition and Their Bio-Safety For Rat Brain
27. Gambogic acid induces growth inhibition and differentiation via upregulation of p21waf1/cip1 expression in acute myeloid leukemia cells
28. Regulation of gambogic acid on hERG potassium channel protein of K562 leukemia cells
29. Development of a safety and efficacy nanoemulsion delivery system encapsulated gambogic acid for acute myeloid leukemia in vitro and in vivo
30. Gambogic acid synergistically potentiates cisplatin-induced apoptosis in non-small-cell lung cancer through suppressing NF-κB and MAPK/HO-1 signalling
31. Mechanisms of Gambogic Acid-Induced Apoptosis in Non-Small Cell lung cancer Cells in Relation to Transferrin Receptors
32. Suppression of NF-κB Signaling and P-glycoprotein Function by Gambogic Acid Synergistically Potentiates Adriamycin -induced Apoptosis in lung cancer
33. Development of a More Efficient Albumin-Based Delivery System for Gambogic Acid with Low Toxicity for lung cancer Therapy
34. Combined therapy with EGFR TKI and gambogic acid for overcoming resistance in EGFR‑T790M mutant lung cancer
35. Combination of gambogic acid with cisplatin enhances the antitumor effects on cisplatin-resistant lung cancer cells by downregulating MRP2 and LRP expression
36. Gambogic acid improves non-small cell lung cancer progression by inhibition of mTOR signaling pathway
37. Gambogic Acid Induces Apoptosis of Non-Small Cell lung cancer (NSCLC) Cells by Suppressing Notch Signaling
38. Gambogic acid induces apoptosis of SK-MES-1 lung cancer cells
39. Gambogic acid-induced autophagy in nonsmall cell lung cancer NCI-H441 cells through a reactive oxygen species pathway
40. Fine-Tuning Vitamin E-Containing Telodendrimers for Efficient Delivery of Gambogic Acid in colon cancer Treatment
41. Effect of Gambogic acid on proliferation and invasion in colon cancer LoVo cell line
42. Gambogic acid suppresses colon cancer cell activity in vitro
43. Screening for natural compounds with anticancer activity in colon cancer cells identifies cytotoxic gambogic acid analogues
44. ROS-Mediated Autophagy Induced by Dysregulation of Lipid Metabolism Plays a Protective Role in colorectal cancer Cells Treated with Gambogic Acid
45. Gambogic acid inhibits growth, induces apoptosis, and overcomes drug resistance in human colorectal cancer cells
46. Gambogic acid-loaded biomimetic nanoparticles in colorectal cancer treatment
47. Gambogic Acid Efficiently Kills Stem-Like colorectal cancer Cells by Upregulating ZFP36 Expression
48. Anti-EGFR-iRGD recombinant protein modified biomimetic nanoparticles loaded with gambogic acid to enhance targeting and antitumor ability in colorectal cancer treatment
49. Suppression of APC production during apoptosis of human colorectal cancer cell line SW480 induced by gambogic acid
50. Effect of gambogic acid on cell apoptosis and expressions of Bax, Bcl-2 and Caspase-3 in colorectal cancer cells with
51. Gambogic acid potentiates the chemosensitivity of colorectal cancer cells to 5‑fluorouracil by inhibiting proliferation and inducing apoptosis
52. Gambogic acid regulates the migration and invasion of colorectal cancer via microRNA‑21‑mediated activation of phosphatase and tensin homolog
53. Gambogic acid reverses oxaliplatin resistance in colorectal cancer by increasing intracellular platinum levels
54. Gambogic Acid Sensitizes ovarian cancer Cells to Doxorubicin Through ROS-Mediated Apoptosis
55. Gambogic acid inhibits the growth of ovarian cancer tumors by regulating p65 activity
56. Nanodelivery of gambogic acid by functionalized graphene enhances inhibition of cell proliferation and induces G0/G1 cell cycle arrest in cervical, ovarian, and prostate cancer cells
57. Gambogic acid inhibited the growth of ovarian cancer via regulating p65 activity
58. Gambogic Acid Combined With CdTe QDs For Leukemia Cancer Cells Inhibition and Their Bio-Safety For Rat Brain
59. The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma
60. Bromodomain‑containing protein 4 is critical for the antiproliferative and pro‑apoptotic effects of gambogic acid in anaplastic thyroid cancer

Ganoderma lucidum

1. The anti‐tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes
2. Effects of Ganopoly® (A Ganoderma lucidum Polysaccharide Extract) on the Immune Functions in Advanced‐Stage Cancer Patients
3. Anti‐Inflammatory and Anti‐Tumor‐Promoting Effects of Triterpene Acids and Sterols from the Fungus Ganoderma lucidum
4. Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms
5. Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF‐7 human breast cancer cell
6. Effects of ganoderma lucidum on apoptotic and anti‐inflammatory function in HT‐29 human colonic carcinoma cells
7. Anticancer effects of Ganoderma lucidum: a review of scientific evidence
8. Free radical scavenging of Ganoderma lucidum polysaccharides and its effect on antioxidant enzymes and immunity activities in cervical carcinoma rats
9. Ganoderma lucidum Polysaccharides: Immunomodulation and Potential Anti-Tumor Activities
10. Ganoderma lucidum (Reishi) in cancer treatment
11. Ganoderma lucidum suppresses motility of highly invasive breast and prostate cancer cells
12. Ganoderma lucidum suppresses angiogenesis through the inhibition of secretion of VEGF and TGF-β1 from prostate cancer cells
13. Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3
14. Biologic Activity of Spores and Dried Powder from Ganoderma lucidum for the Inhibition of Highly Invasive Human Breast and Prostate Cancer Cells
15. Ganoderma Lucidum(Reishi) in Cancer Treatment
16. Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF‐7 human breast cancer cell
17. Ganoderma lucidum Suppresses Growth of Breast Cancer Cells Through the Inhibition of Akt/NF-κB Signaling
18. Ganoderma lucidum inhibits proliferation of human breast cancer cells by down-regulation of estrogen receptor and NF-κB signaling
19. A novel polysaccharide from Se-enriched Ganoderma lucidum induces apoptosis of human breast cancer cells
20. Ganoderma lucidum (Reishi) Inhibits Cancer Cell Growth and Expression of Key Molecules in Inflammatory Breast Cancer
21. [Effect of Ganoderma lucidum polysaccharides on intestinal mucosal immune system in H22 liver cancer bearing mice].
22. Research about the apoptosis of liver cancer HepG2 cells induced by Ganoderma lucidum polysaccharides
23. Ganoderma lucidum polysaccharides peptide inhibits the growth of vascular endothelial cell and the induction of VEGF in human lung cancer cell
24. Effects of Water-Soluble Ganoderma lucidum Polysaccharides on the Immune Functions of Patients with Advanced lung cancer
25. A Randomized, Placebo-Controlled, Multicenter Study of Ganoderma lucidum (W.Curt.:Fr.) Lloyd (Aphyllophoromycetideae) Polysaccharides (Ganopoly®) in Patients with Advanced lung cancer
26. The mushroom Ganoderma lucidum suppresses breast-to-lung cancer metastasis through the inhibition of pro-invasive genes
27. Protection Against lung cancer Patient Plasma-Induced Lymphocyte Suppression by Ganoderma Lucidum Polysaccharides
28. Ganoderma lucidum targeting lung cancer signaling: A review
29. Khz (fusion of ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis in A549 human lung cancer cells by generating reactive oxygen species and decreasing the mitochondrial membrane potential
30. Effects of Ganoderma lucidum essence powder and Ganoderma Lucidum spore powder on immune function of mice with Lewis lung cancer
31. Antiproliferative Effects of a Triterpene-Enriched Extract from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), on Human lung cancer Cells
32. Ganodermanontriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth of colon cancer cells through ß-catenin signaling
33. Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.
34. Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum
35. Inhibition of colon cancer cells by Ganoderma lucidum triterpenes.
36. Cytotoxic Selectivity of Ganoderma lucidumin colon cancer through Cyclooxygenase 2 (COX-2) as Its Molecular Target
37. Ganoderma lucidum extract inhibits proliferation of SW 480 human colorectal cancer cells
38. Anticarcinogenic effects of water extract of sporoderm-broken spores of Ganoderma lucidum on colorectal cancer in vitro and in vivo
39. Restoration of the tumor-suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells
40. Ganoderma lucidum polysaccharide alleviating colorectal cancer by alteration of special gut bacteria and regulation of gene expression of colonic epithelial cells
41. Immune Responses to Water-Soluble Ling Zhi Mushroom Ganoderma lucidum (W.Curt.:Fr.) P. Karst. Polysaccharides in Patients with Advanced colorectal cancer
42. The ethanol extracts of sporoderm-broken spores of Ganoderma lucidum inhibit colorectal cancer in vitro and in vivo
43. Abstract B12: Effect of Ganoderma lucidum on DNA damage and DNA repair in colorectal cancer cell lines
44. Ganoderma lucidum polysaccharides induce cytotoxicity in colorectal cancer cells through inducing autophagosome accumulation and inhibiting autophagic flux
45. Ganoderma Lucidum induces oxidative DNA damage and enhances the effect of 5-Fluorouracil in colorectal cancer in vitro and in vivo
46. Ganoderma lucidum causes apoptosis in leukemia, lymphoma and multiple myeloma cells
47. Ganoderma lucidum polysaccharides can induce human monocytic leukemia cells into dendritic cells with immuno-stimulatory function
48. Ganoderma lucidum polysaccharides in human monocytic leukemia cells: from gene expression to network construction
49. Enhanced induction of mitochondrial damage and apoptosis in human leukemia HL-60 cells by the Ganoderma lucidum and Duchesnea chrysantha extracts
50. Ganoderma lucidum induced apoptosis in NB4 human leukemia cells: Involvement of Akt and Erk
51. Ganoderma lucidum Extracts Inhibited leukemia WEHI-3 Cells in BALB/c Mice and Promoted an Immune Response in Vivo
52. Ganoderma lucidum Polysaccharides Induce Macrophage-Like Differentiation in Human leukemia THP-1 Cells via Caspase and p53 Activation
53. Active lipids of Ganoderma lucidum spores-induced apoptosis in human leukemia THP-1 cells via MAPK and PI3K pathways
54. Ganoderma lucidum polysaccharide exerts anti-tumor activity via MAPK pathways in HL-60 acute leukemia cells
55. Regulation of cell cycle transition and induction of apoptosis in HL-60 leukemia cells by the combination of Coriolus versicolor and Ganoderma lucidum
56. Antrodia camphorata and ganoderma lucidum composition having functionality to inhibit renal cancer cell growth and enhance kidney functionmposition
57. Modulatory effect of Ganoderma lucidum polysaccharides on serum antioxidant enzymes activities in ovarian cancer rats
58. Ganoderma lucidum exerts anti-tumor effects on ovarian cancer cells and enhances their sensitivity to cisplatin
59. Ganoderma lucidum inhibits proliferation of human ovarian cancer cells by suppressing VEGF expression and up-regulating the expression of connexin 43
60. Effect of reversion of ganoderma lucidum polysaccharides on cisplatin resistant in ovarian cancer cells and its mechanism
61. Ganoderma lucidum polysaccharides resistant ovarian cancer cells induced by experimental study
62. Effect of Ganoderma lucidum on drug resistance of cisplantin-resistant ovarian cancer cell line

Ganoderma tsugae

1. Ganoderma tsugae extracts inhibit colorectal cancer cell growth via G2/M cell cycle arrest
2. Antioxidant and radical scavenging properties of extracts from Ganoderma tsugae
3. Antitumor active protein-containing glycans from the Chinese mushroom Songshan Lingzhi, Ganoderma tsugae mycelium
4. Induction of premature senescence in human lung cancer by fungal immunomodulatory protein from Ganoderma tsugae
5. Structure and antitumor activities of the water-soluble polysaccharides from Ganoderma tsugae mycelium
6. Ganoderma tsugae extract inhibits expression of epidermal growth factor receptor and angiogenesis in human epidermoid carcinoma cells: In vitro and in vivo
7. Effects of polysaccharides (FI0-c) from mycelium of Ganoderma tsugae on proinflammatory cytokine production by THP-1 cells and human PBMC (II).
8. Antitumor Active Polysaccharides from the Chinese Mushroom Songshan Lingzhi, the Fruiting Body of Ganoderma tsugae
9. Activity in human lung cancer cells by fungal immunomodulatory protein from Ganoderma tsugae
10. Ganoderma tsugae extract inhibits growth of HER2-overexpressing cancer cells via modulation of HER2/PI3K/Akt signaling pathway
11. Comparative Studies of Various Ganoderma Species and Their Different Parts with Regard to Their Antitumor and Immunomodulating Activities In Vitro
12. Effects of a Chinese medical herbs complex on cellular immunity and toxicity-related conditions of breast cancer patients
13. Chemical Composition and Medicinal Value of the New Ganoderma tsugae var. jannieae CBS-120304 Medicinal Higher Basidiomycete Mushroom
14. Anti-tumor and immunoregulatory activitiesof Ganoderma lucidum and its possible mechanisms
15. Recombinant FIP-gat, a Fungal Immunomodulatory Protein from Ganoderma atrum, Induces Growth Inhibition and Cell Death in Breast Cancer Cells
16. Anti-androgenic activities of Ganoderma lucidum Ganoderma lucidum might be a useful ingredient for the treatment of benign prostatic hyperplasia (BPH).
17. Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells
18. Ganoderma tsugae induced ROS-independent apoptosis and cytoprotective autophagy in human chronic myeloid leukemia cells
19. A whole-genome microarray approach to signal pathway of growth inhibition effects of Ganoderma tsugae extracts on lung cancer cells
20. Ganoderma tsugae extracts induce cell cycle arrest and apoptosis in lung cancer cells

Genistein

1. Effect of genistein on in vitro and in vivo models of cancer
2. Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo
3. Growth-inhibitory effects of the natural phyto-oestrogen genistein in MCF-7 human breast cancer cells
4. Genistein exerts multiple suppressive effects on human breast carcinoma cells
5. Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice
6. Genistein inhibition of the growth of human breast cancer cells: independence from estrogen receptors and the multi-drug resistance gene
7. Effects of soy phytoestrogens genistein and daidzein on breast cancer growth
8. The effect of genistein aglycone on cancer and cancer risk: a review of in vitro, preclinical, and clinical studies
9. Genistein‐induced upregulation of p21 WAF1 , downregulation of cyclin B, and induction of apoptosis in prostate cancer cells
10. Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro
11. Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation
12. Genistein Inhibits NF-kB Activation in Prostate Cancer Cells
13. Rationale for the use of genistein‐containing soy matrices in chemoprevention trials for breast and prostate cancer
14. Retracted: Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells
15. Dietary Genistein Inhibits Metastasis of Human Prostate Cancer in Mice
16. Protection against breast cancer with genistein: a component of soy
17. Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells.
18. Genistein These include chemoprevention of breast and prostate cancers, cardiovascular disease and post-menopausal ailments.
19. Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein
20. Genistein: does it prevent or promote breast cancer?
21. Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases
22. Induction of Differentiation and DNA Strand Breakage in Human HL-60 and K-562 leukemia Cells by Genistein
23. The natural tyrosine kinase inhibitor genistein produces cell cycle arrest and apoptosis in Jurkat T-leukemia cells
24. Genistein induces topoisomerase IIbeta- and proteasome-mediated DNA sequence rearrangements: Implications in infant leukemia
25. Selection of myeloid progenitors lacking BCR/ABL mRNA in chronic myelogenous leukemia patients after in vitro treatment with the tyrosine kinase inhibitor genistein
26. Synergistic Effect of 5-Aza-2′-Deoxycytidine and Genistein in Combination Against leukemia
27. Comparison of the Effects of Genistein and Amsacrine on leukemia Cell Proliferation
28. Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein
29. Genistein inhibited proliferation and induced apoptosis in acute lymphoblastic leukemia, lymphoma and multiple myeloma cells in vitro
30. Genistein exhibits preferential cytotoxicity to a leukemogenic variant but induces differentiation of a non-leukemogenic variant of the mouse monocytic leukemia Mm cell line
31. p53-Independent Apoptosis Induced by Genistein in lung cancer Cells
32. Genistein‐induced G2‐m arrest, P21WAF1 upregulation, and apoptosis in a non‐small‐cell lung cancer cell line
33. Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells
34. Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor kappa B in nonsmall cell lung cancer cell lines
35. p21 response to DNA damage induced by genistein and etoposide in human lung cancer cells
36. Genistein exhibits anti-cancer effects via down-regulating FoxM1 in H446 small-cell lung cancer cells
37. Genistein downregulates de novo lipid synthesis and impairs cell proliferation in human lung cancer cells
38. Protection of p53 Wild Type Cells From Taxol by Genistein in the Combined Treatment of lung cancer
39. Genistein inhibits A549 human lung cancer cell proliferation via miR-27a and MET signaling
40. Genistein enhances the effect of cisplatin on the inhibition of non‑small cell lung cancer A549 cell growth in vitro and in vivo
41. Enhancement of Experimental colon cancer by Genistein
42. Genistein induces apoptosis and topoisomerase II-mediated DNA breakage in colon cancer cells
43. Estrogen Receptor β mRNA in colon cancer Cells: Growth Effects of Estrogen and Genistein
44. Inhibition of proliferation and induction of apoptosis by genistein in colon cancer HT-29 cells
45. A combination of indole-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy
46. Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells
47. Genistein Inhibits Insulin-Like Growth Factor-I Receptor Signaling in HT-29 Human colon cancer Cells: A Possible Mechanism of the Growth Inhibitory Effect of Genistein
48. Genistein attenuates WNT signaling by up-regulating sFRP2 in a human colon cancer cell line
49. Genistein Increases Gene Expression by Demethylation of WNT5a Promoter in colon cancer Cell Line SW1116
50. Genistein Affects Histone Modifications on Dickkopf-Related Protein 1 (DKK1) Gene in SW480 Human colon cancer Cell Line
51. Nonsteroidal anti‐inflammatory drug‐activated gene (NAG‐1) is induced by genistein through the expression of p53 in colorectal cancer cells
52. Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis
53. Genistein Inhibits Human colorectal cancer Growth and Suppresses MiR-95, Akt and SGK1
54. Genistein induces activation of the mitochondrial apoptosis pathway by inhibiting phosphorylation of Akt in colorectal cancer cells
55. Abstract 4000: Genistein-induced reduction of Wnt/beta-catenin pathway activity in colorectal cancer cell lines correlates with inhibition of proliferation and colony growth in soft agar .
56. SYMPOSIUMS: GENISTEIN, EPIGENETIC & colorectal cancer
57. Genistein: mechanisms of action in colorectal cancer
58. Genistein and Its Role in Regulation of AP-1 in colorectal cancer
59. Apoptosis of Human colorectal cancer Cell SW480 Induced by Genistein and Its Molecular Mechanism
60. In vitro study on estrogenic effects of quercetin and genistein on a model of colorectal cancer cells
61. Genistein is an effective stimulator of sex hormone-binding globulin production in hepatocarcinoma human liver cancer cells and suppresses proliferation of these cells in culture
62. Glucuronidation of the soyabean isoflavones genistein and daidzein by human liver is related to levels of UGT1A1 and UGT1A9 activity and alters isoflavone response in the MCF-7 human breast cancer cell line
63. Genistein Reinforces the Inhibitory Effect of Cisplatin on liver cancer Recurrence and Metastasis after Curative Hepatectomy
64. Genistein-loaded nanoparticles of star-shaped diblock copolymer mannitol-core PLGA–TPGS for the treatment of liver cancer
65. Genistein-triggered anticancer activity against liver cancer cell line HepG2 involves ROS generation, mitochondrial apoptosis, G2/M cell cycle arrest and inhibition of cell migration
66. Genistein reduced colon cancer metastasis to liver through regulating the expression of metastasis-related genes in xenographed mice model
67. Genistein-induced apoptosis and autophagocytosis in ovarian cancer cells
68. Inhibitory Effect of Genistein and Daidzein on ovarian cancer Cell Growth
69. Modulation of microRNA associated with ovarian cancer cells by genistein.
70. Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways
71. Oncogenic MicroRNA-27a is a Target for Genistein in ovarian cancer Cells
72. Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB
73. Pro-apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells
74. Genistein as a Potential Anticancer Agent against ovarian cancer
75. Gene Expression Profiling in Response to Estradiol and Genistein in ovarian cancer Cells
76. Genistein induces apoptosis in ovarian cancer cells via different molecular pathways depending on Breast Cancer Susceptibility gene-1 (BRCA1) status
77. Antibodies directed against L1-CAM synergize with Genistein in inhibiting growth and survival pathways in SKOV3ip human ovarian cancer cells
78. Apoptosis induced by 7-difluoromethoxyl-5,4′-di-n-octyl genistein via the inactivation of FoxM1 in ovarian cancer cells
79. Genistein, a soy phytoestrogen, prevents the growth of BG-1 ovarian cancer cells induced by 17β-estradiol or bisphenol A via the inhibition of cell cycle progression
80. Anticancer effect of genistein on BG-1 ovarian cancer growth induced by 17 β-estradiol or bisphenol A via the suppression of the crosstalk between estrogen receptor alpha and insulin-like growth factor-1 receptor signaling pathways
81. Genistein suppressed epithelial–mesenchymal transition and migration efficacies of BG-1 ovarian cancer cells activated by estrogenic chemicals via estrogen receptor pathway and downregulation of TGF-β signaling pathway
82. 7‑difluoromethoxyl‑5,4’‑di‑n‑octyl genistein inhibits ovarian cancer stem cell characteristics through the downregulation of FOXM1
83. FOXO3a-mediated suppression of the self-renewal capacity of sphere-forming cells derived from the ovarian cancer SKOV3 cell line by 7-difluoromethoxyl-5,4′-di-n-octyl genistein
84. A genistein derivative, ITB-301, induces microtubule depolymerization and mitotic arrest in multidrug-resistant ovarian cancer
85. Let-7d increases ovarian cancer cell sensitivity to a genistein analog by targeting c-Myc
86. Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer
87. The effect of short-term oral phytoestrogen supplementation on the concentration of plasma and prostate tissue genistein and daidzein as well as on hormones of the hypothalamic-pituitary-testicular axis in prostate cancer patients
88. Genistein Prevents Nuclear Factor-Kappa B Activation and Acute Lung Injury Induced by Lipopolysaccharide
89. Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor kappa B in nonsmall cell lung cancer cell lines
90. Apoptotic effect of genistein on human colon cancer cells via inhibiting the nuclear factor-kappa B (NF-κB) pathway
91. The soy isoflavone genistein blunts nuclear factor kappa-B, MAPKs and TNF-α activation and ameliorates muscle function and morphology in mdx mice
92. Inhibition of LPS Induced iNOS, COX-2 and Cytokines Expression by Genistein−4′−O−α−L−Rhamnopyranosyl−(1−2)−β−D−Glucopyranoside through the NF−κB Inactivation in RAW 264
93. Time Course for Inhibition of Lipopolysaccharide-induced Lung Injury by Genistein: Relationship to Alteration in Nuclear Factor-Kappa B Activity and Inflammatory Agents
94. Genetics, Epigenetics and GenomicsP269Curcumin and genistein inhibit TNF-alpha-inducted matrix metalloproteinase-9 (MMP-9) expression by repressing NF-kappa B-mediated transcription
95. Cells Exposed to GenisteinExpression in TLR4Stimulated of NF{kappa}B-Dependent Gene A Critical Role for p53 in theControl
96. The soy isoflavone genistein blunts nuclear factor kappa-B,MAPKs and TNF-aactivation and ameliorates muscle functionand morphology inmdxmice
97. Time course for inhibition of lung injury by genistein: alteration in NF-kappa B activity and inflammatory agents
98. 17β-Estradiol, Genistein, and 4-Hydroxytamoxifen Induce the Proliferation of Thyroid Cancer Cells through the G Protein-Coupled Receptor GPR30
99. Combination with genistein enhances the efficacy of photodynamic therapy against human anaplastic thyroid cancer cells†
100. The effects of thymoquinone and genistein treatment on telomerase activity, apoptosis, angiogenesis, and survival in thyroid cancer cell lines
101. Genistein inhibits human papillary thyroid cancer cell detachment, invasion and metastasis
102. Genotoxicity Evaluation of the Soybean Isoflavone Genistein in Human Papillary Thyroid Cancer Cells. Study of Its Potential Use in Thyroid Cancer Therapy
103. Genistein inhibits the stemness properties of prostate cancer cells through targeting Hedgehog–Gli1 pathway
104. Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway
105. Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells
106. Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling
107. Genistein down-regulates Notch-1 expression and inactivates Hedgehog signaling pathway in pancreatic cancer cells

Ginkgo Biloba

1. Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-α1
2. Ginkgo biloba extracts and cancer: a research area in its infancy
3. Effects of Ginkgo biloba extract on cell proliferation and cytotoxicity in human hepatocellular carcinoma cells
4. Ginkgo biloba extract kaempferol inhibits cell proliferation and induces apoptosis in pancreatic cancer cells
5. Ginkgo biloba extract inhibits tumor necrosis factor-α–induced reactive oxygen species generation, transcription factor activation, and cell adhesion molecule
6. Kaempferol and quercetin, components of Ginkgo biloba extract (EGb 761), induce caspase‐3‐dependent apoptosis in oral cavity cancer cells
7. Ginkgo biloba and ovarian cancer prevention: epidemiological and biological evidence
8. Cancer-related overexpression of the peripheral-type benzodiazepine receptor and cytostatic anticancer effects of Ginkgo biloba extract (EGb 761)
9. mRNA expression profile of a human cancer cell line in response to Ginkgo biloba extract: Induction of antioxidant response and the golgi system
10. Phase II study of Ginkgo biloba in irradiated brain tumor patients: effect on cognitive function, quality of life, and mood
11. Ginkgo biloba extracts and cancer: a research area in its infancy
12. The use of Ginkgo biloba for the prevention of chemotherapy-related cognitive dysfunction in women receiving adjuvant treatment for breast cancer, N00C9
13. Drug-induced inhibition of the peripheral-type benzodiazepine receptor expression and cell proliferation in human breast cancer cells.
14. Ginkgo biloba Extract Kaempferol Inhibits Cell Proliferation and Induces Apoptosis in Pancreatic Cancer Cells
15. Ginkgo biloba and risk of cancer: secondary analysis of the Ginkgo Evaluation of Memory (GEM) Study
16. Kaempferol and quercetin, components of Ginkgo biloba extract (EGb 761), induce caspase‐3‐dependent apoptosis in oral cavity cancer cells
17. Specialty Supplements and Prostate Cancer Risk in the VITamins And Lifestyle (VITAL) Cohort
18. Ginkgo biloba extract (EGb 761) induces apoptosis by the activation of caspase-3 in oral cavity cancer cells
19. Hepatocellular Carcinomas in B6C3F1 Mice Treated with Ginkgo biloba Extract for Two Years Differ from Spontaneous Liver Tumors in Cancer Gene Mutations and Genomic Pathways
20. Studies of Ginkgo Biloba Testa Polysaccharides in Inhibiting liver cancer and Inducing Apoptosis of the liver cancer Cell in Mice
21. Extract of Ginkgo biloba exacerbates liver metastasis in a mouse colon cancer Xenograft model
22. Effects of total flavonoids in Ginkgo biloba leaves on proliferation and apoptosis of human liver cancer cell line HepG2 in vitro
23. The effects of Ginkgo biloba leaf flavonoids and Quercetin on proliferation or Apoptosis of human liver cancer cell line HepG2
24. Ginkgo biloba Extract Decreases Non-Small Cell lung cancer Cell Migration by Downregulating Metastasis-Associated Factor Heat-Shock Protein 27
25. Ginkgo biloba exocarp extracts inhibits angiogenesis and its effects on Wnt/β-catenin-VEGF signaling pathway in Lewis lung cancer
26. Ginkgo biloba exocarp extracts induces apoptosis in Lewis lung cancer cells involving MAPK signaling pathways
27. Anti-metastasis effect of Ginkgo bilobaexocarp extracts on metastasis of Lewis lung cancer in C_(57)BL/6J mice and its mechanism
28. Ginkgo Biloba Extract Can Inhibit Non-Small Cell lung cancer Cell Metastasis Through Suppression Of HSP27 Expression
29. Effects of Ginkgo Biloba Extract on Proliferation of Non-small Cell lung cancer PC-9 Cells
30. Abstract 3325: Ginkgetin, a biflavonoid derived from leaves of Ginkgo biloba, induces autophagic cell death in non-small cell lung cancer via p62
31. Ginkgo biloba Extract Decreases Non-Small Cell lung cancer Cell Migration by Downregulating Metastasis-Associated Factor Heat-Shock Protein 27
32. Effects of ginseng and Ginkgo biloba on the efficacy of 5-flurouracil in colon cancer cells
33. Effect of Ginkgo biloba extract EGb761 on apoptosis of K-ras mutational human colon cancer cells DLD1 and its mechanism
34. lincRNA-p21 Mediates the Anti-Cancer Effect of Ginkgo Biloba Extract EGb 761 by Stabilizing E-Cadherin Protein in colon cancer
35. Phase II Study of Combined 5‐Fluorouracil/ Ginkgo biloba Extract (GBE 761 ONC) Therapy in 5‐Fluorouracil Pretreated Patients with Advanced colorectal cancer
36. Ginkgo biloba extract EGb 761–induced upregulation of LincRNA-p21 inhibits colorectal cancer metastasis by associating with EZH2
37. Ginkgo biloba extract 761 enhances 5-fluorouracil chemosensitivity in colorectal cancer cells through regulation of high mobility group-box 3 expression
38. Ginkgo biloba L. leaf extract offers multiple mechanisms in bridling N-methylnitrosourea – mediated experimental colorectal cancer
39. Phase II study of combined 5-fluorouracil/ginkgo biloba extract (GBE 761 ONC) therapy in 5-fluorouracil pretreated patients with advanced colorectal cancer
40. Experimental Study on Inhibition of Polysaccharides of Ginkgo Biloba Leaf on Proliferation of Human leukemia Cell
41. Epidemiological and biological evidence for protective effect of ginkgo biloba on ovarian cancer
42. Ginkgo biloba inhibits hydrogen peroxide–induced activation of nuclear factor kappa B in vascular endothelial cells
43. Hyperbaric Oxygen and Ginkgo Biloba Extract Ameliorate Cognitive and Memory Impairment via Nuclear Factor Kappa-B Pathway in Rat Model of Alzheimer’s Disease
44. Ginkgo biloba extract inhibits the expressions of cell adhesion molecules and nuclear factor-kappa B in arterial endothelial cells
45. Ginkgo Biloba Extract Inhibits Metastasis and ERK/Nuclear Factor kappa B (NF-κB) Signaling Pathway in Gastric Cancer

Ginseng extract, ginsenoside Rh

1. Inhibitory effects of ginsenoside Rh2 on tumor growth in nude mice bearing human ovarian cancer cells
2. Inhibition of human ovarian cancer cell proliferation in vitro by ginsenoside Rh2 and adjuvant effects to cisplatin in vivo.
3. Anti-proliferating effects of ginsenoside Rh2 on MCF-7 human breast cancer cells.
4. Inhibitory effect of ginsenoside Rg3 combined with cyclophosphamide on growth and angiogenesis of ovarian cancer.
5. Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer in mice
6. Inhibitory effects by oral administration of ginsenoside Rh2 on the growth of human ovarian cancer cells in nude mice
7. Inhibitory effect of ginsenoside Rg3 on ovarian cancer metastasis
8. Proteomic analysis of the anti-cancer effect of 20S-ginsenoside Rg3 in human colon cancer cell lines
9. Effect and mechanism of ginsenoside Rg3 on postoperative life span of patients with non-small cell lung cancer
10. Effects of ginsenosides Rg3 and Rh2 on the proliferation of prostate cancer cells
11. Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-κB
12. Ginsenoside Rg3 attenuates cell migration via inhibition of aquaporin 1 expression in PC-3M prostate cancer cells
13. Stereospecificity of hydroxyl group at C-20 in antiproliferative action of ginsenoside Rh2 on prostate cancer cells
14. Anti-androgen-independent prostate cancer effects of ginsenoside metabolites In Vitro: Mechanism and possible structure-activity relationship investigation
15. Anti-lung cancer effects of novel ginsenoside 25-OCH3-PPD
16. Ginsenoside F2 induces apoptosis accompanied by protective autophagy in breast cancer stem cells
17. Ginsenoside-Rb1 acts as a weak phytoestrogen in MCF-7 human breast cancer cells
18. Antiangiogenic Effect of Capecitabine Combined with Ginsenoside Rg3 on Breast Cancer in Mice
19. Anti-breast cancer activity of Fine Black ginseng (Panax ginseng Meyer) and ginsenoside Rg5
20. Natural Product Ginsenoside 25-OCH3-PPD Inhibits Breast Cancer Growth and Metastasis through Down-Regulating MDM2
21. Ginsenoside Rh2 induces cell cycle arrest and differentiation in human leukemia cells by upregulating TGF-β expression
22. Anti-cancer effects of ginsenoside compound k on pediatric acute myeloid leukemia cells
23. Characterizing the mechanism for ginsenoside-induced cytotoxicity in cultured leukemia (THP-1) cells
24. Ginsenoside Rg3 inhibits HIF-1α and VEGF expression in patient with acute leukemia via inhibiting the activation of PI3K/Akt and ERK1/2 pathways
25. Ginsenoside Rg1 Induces Apoptosis through Inhibition of the EpoR-Mediated JAK2/STAT5 Signalling Pathway in the TF-1/Epo Human leukemia Cell Line
26. Ginsenoside 20(s)-Rh2 as potent natural histone deacetylase inhibitors suppressing the growth of human leukemia cells
27. Ginsenoside Rh2 Mitigates Pediatric leukemia Through Suppression of Bcl-2 in leukemia Cells
28. Ginsenoside Rh1 inhibits the invasion and migration of THP-1 acute monocytic leukemia cells via inactivation of the MAPK signaling pathway
29. Senescence as A Consequence of Ginsenoside Rg1 Response on K562 Human leukemia Cell Line
30. Pharmaceutical composition for preventing or treating gleevec-resistant leukemia containing ginsenoside F1 or ginsenoside Rg3 as an active ingredient
31. Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4
32. Stereospecific effects of ginsenoside 20-Rg3 inhibits TGF-β1-induced epithelial–mesenchymal transition and suppresses lung cancer migration, invasion and anoikis resistance
33. Ginsenoside Rh2 mediates changes in the microRNA expression profile of human non-small cell lung cancer A549 cells
34. Immunopotentiation and antitumor effects of a ginsenoside Rg3-fortified red ginseng preparation in mice bearing H460 lung cancer cells
35. Anti-tumor activity of three ginsenoside derivatives in lung cancer is associated with Wnt/β-catenin signaling inhibition
36. AD-1, a novel ginsenoside derivative, shows anti-lung cancer activity via activation of p38 MAPK pathway and generation of reactive oxygen species
37. Inhibiting PI3K-AKt signaling pathway is involved in antitumor effects of ginsenoside Rg3 in lung cancer cell
38. Ginsenoside Rg3 sensitizes human non‑small cell lung cancer cells to γ-radiation by targeting the nuclear factor-κB pathway
39. Ginsenoside metabolite compound K enhances the efficacy of cisplatin in lung cancer cells
40. Therapeutic potential of Ginsenoside Rg3 via inhibiting Notch/HES1 pathway in lung cancer cells
41. Proteomic Analysis of the Anti-Cancer Effect of 20S-Ginsenoside Rg3 in Human colon cancer Cell Lines
42. Inhibition of NF-κB by ginsenoside Rg3 enhances the susceptibility of colon cancer cells to docetaxel
43. Compound K, a Ginsenoside Metabolite, Inhibits colon cancer Growth via Multiple Pathways Including p53-p21 Interactions
44. Ginsenoside Rg3 inhibits colon cancer cell migration by suppressing nuclear factor kappa B activity
45. Ginsenoside Rh2 inhibiting HCT116 colon cancer cell proliferation through blocking PDZ-binding kinase/T-LAK cell-originated protein kinase
46. Ginsenoside-Rp1-induced apolipoprotein A-1 expression in the LoVo human colon cancer cell line
47. A Distinctive Pattern of Beauveria bassiana‐biotransformed Ginsenoside Products Triggers Mitochondria/FasL‐mediated Apoptosis in colon cancer Cells
48. Effect of 20(S)-ginsenoside Rh_2 on cell proliferation and cycle of human colon cancer cells
49. MicroRNA‑146a‑5p enhances ginsenoside Rh2‑induced anti‑proliferation and the apoptosis of the human liver cancer cell line HepG2
50. Ginsenoside Rg3 inhibits the migration and invasion of liver cancer cells by increasing the protein expression of ARHGAP9
51. Mechanism of Ginsenoside Rh2 in Enhancing Sensitivity of Human liver cancer HepG2 Cells to Betulinic Acid
52. Composition for preventing or treating liver cancer containing ginsenoside F2
53. Anti-tumor activity of ginsenoside structure modification on the human liver cancer SMMC-7721 cells in vitro
54. Microarray analysis of altered long non-coding RNA expression profile in liver cancer cells treated by ginsenoside Rh2
55. Recent clinical observation of Cidan Capsule with ginsenoside Rg_3 in advanced primary liver cancer
56. Ginsenoside Rh2 enhances anti-tumor immunity through improving liver fatty acid metabolism in non-small cell lung cancer mice
57. Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53
58. Ginsenoside compound K, not Rb1, possesses potential chemopreventive activities in human colorectal cancer
59. Ginsenoside 20(S)-Rh2 exerts anti-cancer activity through targeting IL-6-induced JAK2/STAT3 pathway in human colorectal cancer cells
60. Ginsenoside Rg3 targets cancer stem cells and tumor angiogenesis to inhibit colorectal cancer progression in vivo
61. Ginsenoside Rh4 induces apoptosis and autophagic cell death through activation of the ROS/JNK/p53 pathway in colorectal cancer cells
62. Anti-tumor activity of three novel derivatives of ginsenoside on colorectal cancer cells
63. Ginsenoside Rb2 inhibits epithelial-mesenchymal transition of colorectal cancer cells by suppressing TGF-β/Smad signaling
64. Ginsenoside Rh2 induced human colorectal cancer cell apoptosis through PI3K/AKT/GSK-3βpathway
65. Inhibitory Effects of Ginsenoside Rh2 on Tumor Growth in Nude Mice Bearing Human ovarian cancer Cells
66. Inhibitory effect of ginsenoside Rg3 combined with cyclophosphamide on growth and angiogenesis of ovarian cancer
67. Inhibitory effect of ginsenoside Rg3 on ovarian cancer metastasis
68. Inhibition of human ovarian cancer cell proliferation in vitro by ginsenoside Rh2 and adjuvant effects to cisplatin in vivo.
69. 20(s)-ginsenoside Rg3 promotes apoptosis in human ovarian cancer HO-8910 cells through PI3K/Akt and XIAP pathways
70. Ginsenoside 20(S)-Rg3 Targets HIF-1α to Block Hypoxia-Induced Epithelial-Mesenchymal Transition in ovarian cancer Cells
71. Ginsenoside 20(S)‑Rg3 inhibits the Warburg effect through STAT3 pathways in ovarian cancer cells
72. Ginsenoside-Rb1 targets chemotherapy-resistant ovarian cancer stem cells via simultaneous inhibition of Wnt/β-catenin signaling and epithelial-to-mesenchymal transition
73. Effect of Ginsenoside Rh-2 via Activation of Caspase-3 and Bcl-2-Insensitive Pathway in ovarian cancer Cells
74. Ginsenoside Rb1 inhibits hypoxia-induced epithelial‑mesenchymal transition in ovarian cancer cells by regulating microRNA-25
75. Ginsenoside 20(S)-Rg3 Inhibits the Warburg Effect Via Modulating DNMT3A/ MiR-532-3p/HK2 Pathway in ovarian cancer Cells
76. Ginsenoside 20(S)-Rg3 suppresses ovarian cancer migration via hypoxia-inducible factor 1 alpha and nuclear factor-kappa B signals
77. Effect of Amino Acids on the Generation of Ginsenoside Rg3 Epimers by Heat Processing and the Anticancer Activities of Epimers in A2780 Human ovarian cancer Cells
78. Inhibitory effects of 20 (S)-ginsenoside Rg3 on ovarian cancer growth
79. Effect of ginsenoside Rh2 combined with cisplatin on apoptosis of human ovarian cancer SKOV-3 cells
80. Effects of ginsenoside Rg3 on epigenetic modification in ovarian cancer cells
81. Ginsenoside Rg3 inhibits colon cancer cell migration by suppressing nuclear factor kappa B activity
82. Anti-inflammatory function of ginsenoside Rg1 on alcoholic hepatitis through glucocorticoid receptor related nuclear factor-kappa B pathway
83. Sulfated Derivative of 20(S)-Ginsenoside Rh2 Inhibits Inflammatory Cytokines Through MAPKs and NF-kappa B Pathways in LPS-Induced RAW264.7 Macrophages
84. Ginsenoside 20(S)-Rg3 suppresses ovarian cancer migration via hypoxia-inducible factor 1 alpha and nuclear factor-kappa B signals
85. Effects of Ginsenoside Rg1 on nuclear factor-kappa B activity in beta amyloid protein-treated neural cells
86. Ginsenoside compound K inhibits nuclear factor-kappa B by targeting Annexin A2
87. INHIBITION OF NF-<KAPPA>B BY GINSENOSIDE RB1 AMELIORATES OXIDATIVE STRESS-INDUCED SENESCENCE
88. GW24-e2242 Effects of Ginsenoside-Rbl improving nuclear factor kappa B system in rats with chronic heart failure induced by adriamycin
89. Effect of ginsenoside Rg3 on hypoxia-induced expression of vascular endothelial growth factor and nuclear factor kappa B in Eca-109 and 786-0 cells.
90. Ginsenoside Rb1 attenuates intestinal ischemia-reperfusion- induced liver injury by inhibiting NF-kappa B activation.
91. Ginsenoside improves papillary thyroid cancer cell malignancies partially through upregulating connexin 31
92. Ginsenoside Rg3 Inhibition of Thyroid Cancer Metastasis Is Associated with Alternation of Actin Skeleton
93. Inhibitory of ginsenoside on proliferation of human thyroid cancer cells and expression of C -myc and Bcl -2 protein in vitro

Glycyrrhiza glabra

1. Angiogenic and proliferative effects of the cytokine VEGF in Ehrlich ascites tumor cells is inhibited by Glycyrrhiza glabra
2. Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells
3. Regulation for the proliferation of breast cancer MCF-7 cells by the treatment with an extract of Glycyrrhiza glabra root
4. Modulations of the Bcl-2/Bax Family Were Involved in the Chemopreventive Effects of Licorice Root (Glycyrrhiza uralensis Fisch) in MCF-7 Human Breast Cancer Cell
5. The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD69 expression and immune cell activation in humans
6. (Glycyrrhiza uralensis) root: induction of apoptosis and G1 cell cycle arrest in MCF-7 human breast cancer cells
7. Phytocomplexes from liquorice (Glycyrrhiza glabra L.) leaves—chemical characterization and evaluation of their antioxidant, anti-genotoxic and anti-inflammatory
8. Protective effect of Yashtimadhu (Glycyrrhiza glabra) against side effects of radiation/chemotherapy in head and neck malignancies
9. Effect of gamma irradiation on the antimicrobial and free radical scavenging activities of Glycyrrhiza glabra root
10. Licorice and cancer
11. Evaluation of cytotoxicity activity and NM23 gene expression in T47D breast cancer cell line treated with glycyrrhiza glabra extract
12. Estrogenic activities of extracts of Chinese licorice (Glycyrrhiza uralensis) root in MCF-7 breast cancer cells
13. In-vitro Cytotoxic Screening of Glycyrrhiza glabra L. (Fabaceae): A Natural Anticancer Drug
14. Isoliquiritigenin Inhibits the Growth of Prostate Cancer
15. PC‐SPES, a dietary supplement for the treatment of hormone‐refractory prostate cancer
16. Herbal composition for treating prostate carcinoma Dendranthema morifolium Tzvel, Glycyrrhiza glabra L.
17. Chinese herbal mixture PC SPES in treatment of prostate cancer (review).
18. Anti-tumor effects of PC-SPES, an herbal formulation in prostate cancer.
19. Effect of root extracts of medicinal herb Glycyrrhiza glabra on HSP90 gene expression and apoptosis in the HT-29 colon cancer cell line
20. The Anticancer Effect of Arctium lappa and Glycyrrhiza glabra on HT-29 colon cancer and MCF-7 Breast Cancer Cell Lines

Grape Seed Extract

1. An active constituent of grape seed extract, exhibits anti-proliferative, pro-apoptotic and anti-tumorigenic effects against prostate carcinoma xenograft growth
2. Synergistic anti-cancer effects of grape seed extract and conventional cytotoxic agent doxorubicin against human breast carcinoma cells
3. Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cells
4. Anticancer and cancer chemopreventive potential of grape seed extract and other grape-based products
5. Grape seed extract inhibits advanced human prostate tumor growth and angiogenesis and upregulates insulin‐like growth factor binding protein‐3
6. Grape seed extract induces apoptotic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial
7. Oral grape seed extract inhibits prostate tumor growth and progression in TRAMP mice
8. Chemoprevention by grape seed extract and genistein in carcinogen-induced mammary cancer in rats is diet dependent
9. Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells
10. Antiproliferative and apoptotic effects triggered by grape seed extract (GSE) versus epigallocatechin and procyanidins on colon cancer cell lines
11. Fractionation of grape seed extract and identification of gallic acid as one of the major active constituents causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells
12. Matrix Metalloproteinases in Cancer Metastasis: Molecular Targets for Prostate Cancer Prevention by Green Tea Polyphenols and Grape Seed Proanthocyanidins
13. Grape seed extract induces anoikis and caspase-mediated apoptosis in human prostate carcinoma LNCaP cells: possible role of ataxia telangiectasia mutated–p53 activation
14. Inhibition of NF-κB pathway in grape seed extract-induced apoptotic death of human prostate carcinoma DU145 cells
15. Fractionation of high molecular weight tannins in grape seed extract and identification of procyanidin B2-3,3′-di-O-gallate as a major active constituent causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells
16. The cytotoxic effects of a novel IH636 grape seed proanthocyanidin extract on cultured human cancer cells
17. Grape seed proanthocyanidins induce apoptosis and inhibit metastasis of highly metastatic breast carcinoma cells
18. Effect of Grape Seed Proanthocyanidins on Colon Aberrant Crypts and Breast Tumors in a Rat Dual-Organ Tumor Model
19. Double-blind, placebo-controlled, randomised phase II trial of IH636 grape seed proanthocyanidin extract (GSPE) in patients with radiation-induced breast induration
20. Induction of Apoptosis in Human leukemia Cells by Grape Seed Extract Occurs via Activation of c-Jun NH2-Terminal Kinase
21. Tempranillo-derived grape seed extract induces apoptotic cell death and cell growth arrest in human promyelocytic leukemia HL-60 cells
22. Antiproliferative and Apoptotic Effects Triggered by Grape Seed Extract (GSE) versus Epigallocatechin and Procyanidins on colon cancer Cell Lines
23. Resveratrol potentiates grape seed extract induced human colon cancer cell apoptosis
24. Apoptosis-inducing factor and caspase-dependent apoptotic pathways triggered by different grape seed extracts on human colon cancer cell line Caco-2
25. Grape seed proanthocyanidins inhibit colon cancer-induced angiogenesis through suppressing the expression of VEGF and Ang1
26. Grape Seed Extract Dose-Responsively Decreases Disease Severity in a Rat Model of Mucositis; Concomitantly Enhancing Chemotherapeutic Effectiveness in colon cancer Cells
27. Grape seed extract triggers apoptosis in Caco-2 human colon cancer cells through reactive oxygen species and calcium increase: extracellular signal-regulated kinase involvement
28. Functional modification of adipocytes by grape seed extract impairs their pro-tumorigenic signaling on colon cancer stem cells and the daughter cancer cells
29. Characterization of azoxymethane-induced colon tumor metastasis to lung in a mouse model relevant to human sporadic colorectal cancer and evaluation of grape seed extract efficacy
30. Grape seed extracts modify the outcome of oxaliplatin in colon cancer cells by interfering with cellular mechanisms of drug cytotoxicity
31. Antiproliferative and apoptotic effects of grape seed extract on human colon cancer cell line HCT116
32. Abstract 4116: Grape seed extract impairs adipocyte-colorectal cancer cell interaction and decreases adipocyte-driven colon cancer stem colonosphere formation
33. Resveratrol and grape seed extract combination elevates apoptosis in the colon cancer stem cells, even in the presence of IGF-1, via P53 dependent pathway
34. Grape Seed Proanthocyanidins Inhibit the Growth of Human Non-Small Cell lung cancer Xenografts by Targeting Insulin-Like Growth Factor Binding Protein-3, Tumor Cell Proliferation, and Angiogenic Factors
35. Inhibition of non‐small cell lung cancer cell migration by grape seed proanthocyanidins is mediated through the inhibition of nitric oxide, guanylate cyclase, and ERK1/2
36. MicroRNA-19a/b mediates grape seed procyanidin extract-induced anti-neoplastic effects against lung cancer
37. Differential Effect of Grape Seed Extract against Human Non-small-Cell lung cancer Cells: The Role of Reactive Oxygen Species and Apoptosis Induction
38. Grape seed proanthocyanidins inhibit cigarette smoke condensate‐induced lung cancer cell migration through inhibition of NADPH oxidase and reduction in the binding of p22phox and p47phox proteins
39. Grape Seed Procyanidin Extract Mediates Antineoplastic Effects against lung cancer via Modulations of Prostacyclin and 15-HETE Eicosanoid Pathways
40. [Grape seed proanthocyanidins inhibits the invasion and migration of A549 lung cancer cells].
41. Grape seed procyanidin extract against lung cancer: the role of microrna-106b, bioavailability, and bioactivity
42. A72 MECHANISMS OF lung cancer BIOLOGY: Grape Seed Proanthocyanidin Extract Modulates Rna Exosome Expression In A549 lung cancer Cells
43. Chemoprevention of colorectal cancer by Grape Seed Proanthocyanidin Is Accompanied by a Decrease in Proliferation and Increase in Apoptosis
44. Differential effects of grape seed extract against human colorectal cancer cell lines: The intricate role of death receptors and mitochondria
45. Target Identification of Grape Seed Extract in colorectal cancer Using Drug Affinity Responsive Target Stability (DARTS) Technique: Role of Endoplasmic Reticulum Stress Response Proteins
46. Oligomeric proanthocyanidins (OPCs) from grape seed extract suppress the activity of ABC transporters in overcoming chemoresistance in colorectal cancer cells
47. Antiproliferative and cytotoxic effects of grape pomace and grape seed extracts on colorectal cancer cell lines
48. Abstract 901: Grape seed extract decreases visceral adiposity and impairs the pro-tumorigenic adipose tissue secretions affecting colorectal cancer growth and progression
49. Grape seed procyanidin B2 promotes the autophagy and apoptosis in colorectal cancer cells via regulating PI3K/Akt signaling pathway
50. Abstract 5721: Grape seed extract induces both intrinsic and extrinsic apoptotic pathways in its efficacy against human colorectal cancer cells harboring varying degrees of metastatic potential
51. Oral Administration of Grape Seed Proanthocyanidin Extracts Downregulate RAGE Dependant Nuclear Factor- Kappa BP65 Expression in the Hippocampus of Streptozotocin Induced Diabetic Rats

Grifola frondosa — Maitake

1. Effects of D-Fraction, a polysaccharide from Grifola frondosa on tumor growth involve activation of NK cells
2. Effects of Lentinus Edodes, Grifola Frondosa and Pleurotus Ostreatus Administration on Cancer Outbreak, and Activities of Macrophages and Lymphocytes in Mice
3. Effect of Maitake (Grifola frondosa) D-Fraction on the Activation of NK Cells in Cancer Patients
4. Effects of maitake (Grifola frondosa) D-Fraction on the carcinoma angiogenesis
5. Structural analysis of anti-tumor heteropolysaccharide GFPS1b from the cultured mycelia of Grifola frondosa GF9801
6. Antitumor and immunomodulating activities of a β-glucan obtained from liquid-cultured Grifola frondosa
7. Antitumor activity exhibited by orally administered extract from fruit body of Grifola frondosa (maitake)
8. Grifola frondosa enhances the anti-tumor activity of bone marrow-derived dendritic cell-based immunotherapy against murine colon cancer
9. Antitumor effects of a water-soluble extract from Maitake (Grifola frondosa) on human gastric cancer cell lines
10. Anticancer activities of a chemically sulfated polysaccharide obtained from Grifola frondosa and its combination with 5-fluorouracil against human gastric carcinoma
11. Can Maitake MD-Fraction Aid CancerPatients?
12. Maitake D-fraction:Healingand Preventive Potential for Cancer
13. Antitumoral Effects of D-Fraction from Grifola Frondosa (Maitake) Mushroom in Breast Cancer
14. Maitake (D Fraction) Mushroom Extract Induces Apoptosis in Breast Cancer Cells by BAK-1 Gene Activation
15. Anticancer and Hypoglycemic Effects of Polysaccharides in Edible and Medicinal Maitake Mushroom [Grifola frondosa (Dicks.: Fr.) S. F. Gray]
16. Grifola frondosa (Dicks.: Fr.) S.F. Gray (Maitake Mushroom): Medicinal Properties, Active Compounds, and Biotechnological Cultivation Medicinal effects and modes of action are presented in detail, including anticancer activity, immunostimulation, effects on angiogenesis, reduction of benign prostatic hyperplasia
17. Maitake Mushroom {Grifóla frondosa): Systematic Reviewby theNatural Standard Research Collaboration The author suggested thatmaitake is effective against breast, liver, and lung cancer butless effective against leukemia and stomach and bone can-cers based on this study
18. Compositions and methods for treating prostate disorders
19. Chemopreventive effect of the polysaccharides from Grifola frondosa in colitis-associated colorectal cancer by modulating the Wnt/β-catenin/GSK-3β signaling pathway in C57BL/6 mice
20. Experimental Study on Effect of Grifola Frondosa on Lich-up Function of MΦ and Activity of IL-1 in Mice With lung cancer
21. In Vitro Anti-proliferative and Anti-invasive Effect of Polysaccharide-rich Extracts from Trametes Versicolor and Grifola Frondosa in colon cancer Cells