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    • The Ultimate Dry Fasting Resource
    INTERSTELLAR 88/8: EXTREME WEIGHTLOSS PROTOCOL
    April 17, 2019
    AMPK
    May 1, 2019

    Autophagy (or autophagocytosis) (from the Ancient Greek αὐτόφαγος autóphagos, meaning “self-devouring”[1] and κύτος kýtos, meaning “hollow”[2]) is the natural, regulated mechanism of the cell that removes unnecessary or dysfunctional components.[3] It allows the orderly degradation and recycling of cellular components.[4][5]

    Three forms of autophagy are commonly described: macroautophagy, microautophagy, and chaperone-mediated autophagy (CMA). In macroautophagy, expendable cytoplasmic constituents are targeted and isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome,[6][7] which, in time, fuses with an available lysosome, bringing its specialty process of waste management and disposal; and eventually the contents of the vesicle (now called an autolysosome) are degraded and recycled.

    In disease, autophagy has been seen as an adaptive response to stress, promoting survival of the cell; but in other cases it appears to promote cell death and morbidity. In the extreme case of starvation, the breakdown of cellular components promotes cellular survival by maintaining cellular energy levels.

    The name “autophagy” was in existence and frequently used from the middle of the 19th century[8]. In its present usage, the term autophagy was coined by Belgian biochemist Christian de Duve in 1963 based on his discovery of the functions of lysosome.[3] The identification of autophagy-related genes in yeast in the 1990s allowed researchers to deduce the mechanisms of autophagy,[9][10][11][12][13] which eventually led to the award of the 2016 Nobel Prize in Physiology or Medicine to Japanese researcher Yoshinori Ohsumi.[14]


    1000 Scientific Studies all about Autophagy:

    1. Autophagy in the pathogenesis of disease
    2. Autophagy fights disease through cellular self-digestion
    3. Autophagy: process and function
    4. Methods in Mammalian Autophagy Research
    5. Autophagy regulates lipid metabolism
    6. Autophagy and Metabolism
    7. Autophagy: Renovation of Cells and Tissues
    8. Autophagy as a Regulated Pathway of Cellular Degradation
    9. Autophagy in immunity and inflammation
    10. Autophagy and Aging
    11. Autophagy and the Integrated Stress Response
    12. mTOR regulation of Autophagy
    13. Regulation Mechanisms and Signaling Pathways of Autophagy
    14. Role of Autophagy in cancer
    15. Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy
    16. Induction of Autophagy and inhibition of tumorigenesis by beclin 1
    17. Autophagy in Health and Disease: A Double-Edged Sword
    18. Methods for monitoring Autophagy
    19. AMPK and mTOR regulate Autophagy through direct phosphorylation of Ulk1
    20. LC3 and Autophagy
    21. The role of Autophagy during the early neonatal starvation period
    22. Death by design: apoptosis, necrosis and Autophagy
    23. Autophagy in cell death: an innocent convict?
    24. TFEB Links Autophagy to Lysosomal Biogenesis
    25. Development by Self-Digestion: Molecular Mechanisms and Biological Functions of Autophagy
    26. Autophagy: cellular and molecular mechanisms
    27. A protein conjugation system essential for Autophagy
    28. Self-eating and self-killing: crosstalk between Autophagy and apoptosis
    29. Autophagy: molecular machinery for self-eating
    30. Suppression of basal Autophagy in neural cells causes neurodegenerative disease in mice
    31. Autophagy in Human Health and Disease
    32. Loss of Autophagy in the central nervous system causes neurodegeneration in mice
    33. Parkin is recruited selectively to impaired mitochondria and promotes their Autophagy
    34. Potential therapeutic applications of Autophagy
    35. Apoptosis, Autophagy, and more
    36. Autophagy Suppresses Tumorigenesis through Elimination of p62
    37. Mammalian Autophagy: core molecular machinery and signaling regulation
    38. LC3 conjugation system in mammalian Autophagy
    39. Endoplasmic Reticulum Stress Triggers Autophagy
    40. Autophagy and cancer
    41. The Beclin 1 network regulates Autophagy and apoptosis
    42. Escape of Intracellular Shigella from Autophagy
    43. Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy
    44. Autophagy in infection, inflammation and immunity
    45. Impairment of starvation-induced and constitutive Autophagy in Atg7-deficient mice
    46. A Role for Ubiquitin in Selective Autophagy
    47. Autophagy: dual roles in life and death?
    48. Isofation and charact~~zation of Autophagy-defective mutants of
      Saccharomyces cerevisiae
    49. Autophagy Defends Cells Against Invading Group A Streptococcus
    50. Autophagy as a cell death and tumor suppressor mechanism
    51. Regulation of Mammalian Autophagy in Physiology and Pathophysiology
    52. Autophagy: from phenomenology to molecular understanding in less than a decade
    53. FoxO3 Controls Autophagy in Skeletal Muscle In Vivo
    54. A Unified Nomenclature forAutophagy-related genes
    55. Autophagy in mammalian development and differentiation
    56. Lysosomes and Autophagy in cell death control
    57. Regulation of Autophagy by cytoplasmic p53
    58. Autophagy: in sickness and in health
    59. Network organization of the human Autophagy system
    60. Fission and selective fusion govern mitochondrial segregation and elimination by Autophagy
    61. Autophagy: assays and artifacts
    62. Autophagy Is Activated for Cell Survival after Endoplasmic Reticulum Stress
    63. Autophagy, Immunity, and Microbial Adaptations
    64. A key role for Autophagy and the Autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
    65. Endogenous HMGB1 regulates Autophagy
    66. Human IRGM Induces Autophagy to Eliminate Intracellular Mycobacteria
    67. Tor, a Phosphatidylinositol Kinase Homologue, Controls Autophagy in Yeast
    68. Autophagy mediates the mitotic senescence transition
    69. The molecular machinery of Autophagy: unanswered questions
    70. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
    71. The role of Autophagy in neurodegenerative disease
    72. Autophagy gone awry in neurodegenerative diseases
    73. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 Autophagy gene
    74. Dynamics and diversity in Autophagy mechanisms: lessons from yeast
    75. Autophagy-Dependent Viral Recognition by Plasmacytoid Dendritic Cells
    76. Toll‐like receptors control Autophagy
    77. The AMPK signalling pathway coordinates cell growth, Autophagy and metabolism
    78. Autophagy
    79. The role of Autophagy in cancer development and response to therapy
    80. p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy
    81. Pancreatic cancers require Autophagy for tumor growth
    82. Autophagy in the Eukaryotic Cell
    83. Calpain-mediated cleavage of Atg5 switches Autophagy to apoptosis
    84. α-Synuclein Is Degraded by Both Autophagy and the Proteasome
    85. Autophagy Is Required to Maintain Muscle Mass
    86. Self-consumption: the interplay of Autophagy and apoptosis
    87. Autophagy-deficient mice develop multiple liver tumors
    88. Induction of Autophagy by spermidine promotes longevity
    89. Crosstalk between apoptosis, necrosis and Autophagy
    90. ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
    91. Lithium induces Autophagy by inhibiting inositol monophosphatase
    92. The Role of Autophagy in Cancer: Therapeutic Implications
    93. Emerging regulation and functions of Autophagy
    94. Loss of the Autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
    95. Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages
    96. Autophagy regulation by p53
    97. ROS, mitochondria and the regulation of Autophagy
    98. Autophagy, amyloidogenesis and Alzheimer disease
    99. Molecular dissection of Autophagy: two ubiquitin-like systems
    100. Deconvoluting the context-dependent role for Autophagy in cancer
    101. The Molecular Mechanism of Autophagy
    102. Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
    103. Oxidative Stress and Autophagy
    104. Beclin 1, an Autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
    105. Autophagy and human diseases
    106. Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice
    107. Autophagy in chronically ischemic myocardium
    108. Autophagy and Cell Death
    109. DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis
    110. Tor-Mediated Induction of Autophagy via an Apg1 Protein Kinase Complex
    111. JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy
    112. p62 at the Crossroads of Autophagy, Apoptosis, and Cancer
    113. Autophagy suppresses tumor progression by limiting chromosomal instability
    114. Growth Factor Regulation of Autophagy and Cell Survival in the Absence of Apoptosis
    115. Apoptosis and Autophagy in nigral neurons of patients with Parkinson’s disease
    116. The Double-Edged Sword of Autophagy Modulation in Cancer
    117. Autophagy genes in immunity
    118. Reactive oxygen species are essential for Autophagy and specifically regulate the activity of Atg4
    119. Regulation of Autophagy by ROS: physiology and pathology
    120. The regulation of Autophagy – unanswered questions
    121. Can Autophagy promote longevity?
    122. Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia
    123. Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
    124. Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
    125. Nix is a selective Autophagy receptor for mitochondrial clearance
    126. Protein Turnover Via Autophagy: Implications for Metabolism
    127. Regulation and role of Autophagy in mammalian cells
    128. p62/SQSTM1 forms protein aggregates degraded by Autophagy and has a protective effect on huntingtin-induced cell death
    129. Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion
    130. Autophagy modulation as a potential therapeutic target for diverse diseases
    131. Defective Autophagy leads to cancer
    132. Ambra1 regulates Autophagy and development of the nervous system
    133. Metabolic Control of Autophagy
    134. Autophagy: a regulated bulk degradation process inside cells
    135. Toll-like receptor signalling in macrophages links the Autophagy pathway to phagocytosis
    136. The role for Autophagy in cancer
    137. Autophagy and signaling: their role in cell survival and cell death
    138. Activated Ras requires Autophagy to maintain oxidative metabolism and tumorigenesis
    139. Eating Oneself and Uninvited Guests: Autophagy-Related Pathways in Cellular Defense
    140. Ubiquitination and selective Autophagy
    141. Autophagy in the Cellular Energetic Balance
    142. The mitochondrial permeability transition initiates Autophagy in rat hepatocytes
    143. Selective Autophagy: ubiquitin-mediated recognition and beyond
    144. Unveiling the roles of Autophagy in innate and adaptive immunity
    145. Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in C. elegans
    146. The role of the Atg1/ULK1 complex in Autophagy regulation
    147. Role of Autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
    148. HDAC6 rescues neurodegeneration and provides an essential link between Autophagy and the UPS
    149. In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker
    150. Autophagy: Many paths to the same end
    151. Mechanisms of chaperone-mediated Autophagy
    152. Autophagy in Cancer: Good, Bad, or Both?
    153. Autophagy-Mediated Tumor Promotion
    154. Autophagy and cytokines
    155. Autophagy as a target for anticancer therapy
    156. Autophagy in metazoans: cell survival in the land of plenty
    157. Cargo recognition and trafficking in selective Autophagy
    158. Extensive Involvement of Autophagy in Alzheimer Disease: An Immuno-Electron Microscopy Study
    159. Endogenous MHC Class II Processing of a Viral Nuclear Antigen After Autophagy
    160. Autophagy in neurons: a review.
    161. Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by Autophagy
    162. Age-related Decline in Chaperone-mediated Autophagy
    163. Autophagy Counterbalances Endoplasmic Reticulum Expansion during the Unfolded Protein Response
    164. The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and Autophagy
    165. Autophagy and Human Disease
    166. Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
    167. Autophagy in liver diseases
    168. Autophagy and related mechanisms of lysosome-mediated protein degradation
    169. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates Autophagy in disease pathogenesis
    170. Inhibition of mTOR induces Autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
    171. Historical landmarks of Autophagy research
    172. An Overview of the Molecular Mechanism of Autophagy
    173. Autophagy in skeletal muscle
    174. Life and death partners: apoptosis, Autophagy and the cross-talk between them
    175. During Autophagy mitochondria elongate, are spared from degradation and sustain cell viability
    176. Principles and Current Strategies for Targeting Autophagy for Cancer Treatment
    177. Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice
    178. Autophagy in malignant transformation and cancer progression
    179. Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction.
    180. The dynamic nature of Autophagy in cancer
    181. Autophagy regulates adipose mass and differentiation in mice
    182. Innate and Adaptive Immunity through Autophagy
    183. The ubiquitin kinase PINK1 recruits Autophagy receptors to induce mitophagy
    184. Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy
    185. Autophagy regulation by nutrient signaling
    186. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
    187. Autophagy basics
    188. Exercise-induced BCL2-regulated Autophagy is required for muscle glucose homeostasis
    189. A role for the NAD-dependent deacetylase Sirt1 in the regulation of Autophagy
    190. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on Autophagy genes
    191. Role and Regulation of Starvation-Induced Autophagy in the Drosophila Fat Body
    192. Hypoxia-induced Autophagy: cell death or cell survival?
    193. Autophagy and other vacuolar protein degradation mechanisms
    194. NOD2 stimulation induces Autophagy in dendritic cells influencing bacterial handling and antigen presentation
    195. Autophagy Regulates Programmed Cell Death during the Plant Innate Immune Response
    196. Autophagy: Basic Principles and Relevance to Disease
    197. mTOR: a pharmacologic target for Autophagy regulation
    198. Autophagy and tumorigenesis
    199. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
    200. The role of Autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
    201. Activation of antibacterial Autophagy by NADPH oxidases
    202. Mitochondria and the Autophagy–Inflammation–Cell Death Axis in Organismal Aging
    203. Autophagy
    204. Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates
    205. Cellular Autophagy: surrender, avoidance and subversion by microorganisms
    206. Autophagy and apoptosis dysfunction in neurodegenerative disorders
    207. Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance
    208. Compromised Autophagy and neurodegenerative diseases
    209. Autophagy Gene-Dependent Clearance of Apoptotic Cells during Embryonic Development
    210. Studies on the mechanisms of Autophagy: formation of the autophagic vacuole.
    211. Autophagy in Ischemic Heart Disease
    212. Dopamine-modified α-synuclein blocks chaperone-mediated Autophagy
    213. Cardiac Autophagy is a maladaptive response to hemodynamic stress
    214. Autophagy, organelles and ageing
    215. A Novel Response of Cancer Cells to Radiation Involves Autophagy and Formation of Acidic Vesicles
    216. The selective Autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
    217. Autophagy and aging: keeping that old broom working
    218. Toll-like Receptor 4 Is a Sensor for Autophagy Associated with Innate Immunity
    219. Autophagy and cancer
    220. Autophagy Is Essential for Preimplantation Development of Mouse Embryos
    221. Superoxide is the major reactive oxygen species regulating Autophagy
    222. Mitochondrial DNA that escapes from Autophagy causes inflammation and heart failure
    223. Vitamin D3 Induces Autophagy in Human Monocytes/Macrophages via Cathelicidin
    224. Bif-1 interacts with Beclin 1 through UVRAG and regulates Autophagy and tumorigenesis
    225. ULK1 induces Autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
    226. Autophagy Links Inflammasomes to Atherosclerotic Progression
    227. Sequence variants in the Autophagy gene IRGM and multiple other replicating loci contribute to Crohn’s disease susceptibility
    228. Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy
    229. Structural Basis for Sorting Mechanism of p62 in Selective Autophagy
    230. The apoptosis/Autophagy paradox: autophagic vacuolization before apoptotic death
    231. Autophagy maintains stemness by preventing senescence
    232. Blocked Autophagy Sensitizes Resistant Carcinoma Cells to Radiation Therapy
    233. Chaperone-mediated Autophagy: roles in disease and aging
    234. Autophagy inhibition in combination cancer treatment.
    235. Novel targets for Huntington’s disease in an mTOR-independent Autophagy pathway
    236. Senescence, Apoptosis or Autophagy?
    237. Programmed cell death pathways in cancer: a review of apoptosis, Autophagy and programmed necrosis
    238. Enhancing Immunity Through Autophagy
    239. Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate Autophagy at different stages
    240. Activation of Chaperone-mediated Autophagy during Oxidative Stress
    241. Connecting endoplasmic reticulum stress to Autophagy by unfolded protein response and calcium
    242. Response to myocardial ischemia/reperfusion injury involves Bnip3 and Autophagy
    243. Identification of a candidate therapeutic Autophagy-inducing peptide
    244. Autophagy in infection
    245. A block of Autophagy in lysosomal storage disorders
    246. HDAC6 controls autophagosome maturation essential for ubiquitin‐selective quality‐control Autophagy
    247. Autophagy: for better or for worse
    248. Regulation of starvation- and virus-induced Autophagy by the eIF2α kinase signaling pathway
    249. Autophagy promotes MHC class II presentation of peptides from intracellular source proteins
    250. ERK and cell death: Mechanisms of ERK‐induced cell death – apoptosis, Autophagy and senescence
    251. Targeting Autophagy in cancer
    252. Secretory Autophagy
    253. Cytoprotective roles for Autophagy
    254. Nod1 and Nod2 direct Autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
    255. Small molecules enhance Autophagy and reduce toxicity in Huntington’s disease models
    256. Autophagy at the crossroads of catabolism and anabolism
    257. The Phosphatidylinositol 3‐Kinase Inhibitors Wortmannin and LY294002 Inhibit Autophagy in Isolated Rat Hepatocytes
    258. The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy
    259. Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer’s Disease
    260. Autophagy and oxidative stress associated with gold nanoparticles
    261. The Atg12-Atg5 Conjugate Has a Novel E3-like Activity for Protein Lipidation in Autophagy
    262. The Association of AMPK with ULK1 Regulates Autophagy
    263. Autophagy: a barrier or an adaptive response to cancer
    264. Phosphorylation of Ribosomal Protein S6 Is Inhibitory for Autophagy in Isolated Rat Hepatocytes
    265. The role of Autophagy in the heart
    266. Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
    267. An Overview of Autophagy: Morphology, Mechanism, and Regulation
    268. The Beclin 1–VPS34 complex – at the crossroads of Autophagy and beyond
    269. Consequences of the selective blockage of chaperone-mediated Autophagy
    270. The Microbiome and Butyrate Regulate Energy Metabolism and Autophagy in the Mammalian Colon
    271. Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation
    272. Role and regulation of Autophagy in cancer
    273. Control of Autophagy by oncogenes and tumor suppressor genes
    274. HSV-1 ICP34.5 Confers Neurovirulence by Targeting the Beclin 1 Autophagy Protein
    275. Dengue Virus-Induced Autophagy Regulates Lipid Metabolism
    276. Anti- and pro-tumor functions of Autophagy
    277. Chaperone‐Mediated Autophagy in Aging and Disease
    278. Chaperone-mediated Autophagy: a unique way to enter the lysosome world
    279. The pleiotropic role of Autophagy: from protein metabolism to bactericide
    280. Autophagy delays apoptotic death in breast cancer cells following DNA damage
    281. Autophagy in neurodegenerative disease: friend, foe or turncoat?
    282. Huntingtin Expression Stimulates Endosomal–Lysosomal Activity, Endosome Tubulation, and Autophagy
    283. Two Distinct Vps34 Phosphatidylinositol 3–Kinase Complexes Function in Autophagy and Carboxypeptidase Y Sorting inSaccharomyces cerevisiae
    284. Autophagosome Formation and Molecular Mechanism of Autophagy
    285. p53: The Janus of Autophagy?
    286. The LIR motif – crucial for selective Autophagy
    287. E2F1 regulates Autophagy and the transcription of Autophagy genes
    288. Cargo recognition failure is responsible for inefficient Autophagy in Huntington’s disease
    289. Viruses and Autophagy
    290. Non-selective Autophagy.
    291. Autophagy in the liver
    292. Autophagy and neurodegeneration: when the cleaning crew goes on strike
    293. Autophagy‐based unconventional secretory pathway for extracellular delivery of IL‐1β
    294. NF-κB Activation Represses Tumor Necrosis Factor-α-induced Autophagy
    295. Oxidative stress and Autophagy: the clash between damage and metabolic needs
    296. Interplay of LRRK2 with chaperone-mediated Autophagy
    297. Physiological Functions of Autophagy
    298. Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity
    299. Studies on the mechanisms of Autophagy: maturation of the autophagic vacuole.
    300. Selective Mitochondrial Autophagy, or Mitophagy, as a Targeted Defense Against Oxidative Stress, Mitochondrial Dysfunction, and Aging
    301. Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
    302. Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis
    303. Autophagy: Principles and significance in health and disease
    304. Autophagy failure in Alzheimer’s disease—locating the primary defect
    305. Lipophagy: Connecting Autophagy and Lipid Metabolism
    306. Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival
    307. The Roles of Therapy-Induced Autophagy and Necrosis in Cancer Treatment
    308. Autophagy and apoptosis: what is the connection?
    309. Autophagy as a therapeutic target in cancer
    310. Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
    311. FoxO Transcription Factors Promote Autophagy in Cardiomyocytes
    312. Autophagy: A lysosomal degradation pathway with a central role in health and disease
    313. Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein
    314. Cerebral Ischemia-Hypoxia Induces Intravascular Coagulation and Autophagy
    315. Chaperone-Mediated Autophagy Markers in Parkinson Disease Brains
    316. Autophagy and the Immune System
    317. FLIP-mediated Autophagy regulation in cell death control
    318. Autophagy and multivesicular bodies: two closely related partners
    319. The TBK1 adaptor and Autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
    320. Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains
    321. Activation of Autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
    322. Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
    323. Galectin 8 targets damaged vesicles for Autophagy to defend cells against bacterial invasion
    324. Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance
    325. Differential Effects of Endoplasmic Reticulum Stress-induced Autophagy on Cell Survival
    326. Autophagy in innate and adaptive immunity
    327. Physiological functions of Atg6/Beclin 1: a unique Autophagy-related protein
    328. Autophagy in Idiopathic Pulmonary Fibrosis
    329. ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for Autophagy formation
    330. Autophagy as an immune defense mechanism
    331. Inflammaging: disturbed interplay between Autophagy and inflammasomes
    332. Apoptosis, Autophagy, necroptosis, and cancer metastasis
    333. Neutrophil extracellular trap cell death requires both Autophagy and superoxide generation
    334. Growth Arrest and Autophagy Are Required for Salivary Gland Cell Degradation in Drosophila
    335. Physiological significance of selective degradation of p62 by Autophagy
    336. Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
    337. Autophagy and Cellular Immune Responses
    338. Role of BNIP3 and NIX in cell death, Autophagy, and mitophagy
    339. The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway
    340. Cell death by Autophagy: facts and apparent artefacts
    341. PAMPs and DAMPs: signal 0s that spur Autophagy and immunity
    342. Chloroquine in Cancer Therapy: A Double-Edged Sword of Autophagy
    343. Lysosomal calcium signalling regulates Autophagy through calcineurin and TFEB
    344. Chaperone-mediated Autophagy in protein quality control
    345. Novel System for Monitoring Autophagy in the Yeast Saccharomyces cerevisiae
    346. Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes
    347. Autophagy and apoptosis: where do they meet?
    348. Plant Autophagy—more than a starvation response
    349. Regulation of Autophagy by the inositol trisphosphate receptor
    350. Selective degradation of p62 by Autophagy
    351. Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and Autophagy
    352. MicroRNA regulation of Autophagy
    353. Autophagy and Autophagy-related proteins in the immune system
    354. Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia
    355. Autophagy and neurodegeneration
    356. Apoptosis and Autophagy: regulatory connections between two supposedly different processes
    357. A critical role for the Autophagy gene Atg5 in T cell survival and proliferation
    358. Control of Autophagy as a therapy for neurodegenerative disease
    359. Atg8: an Autophagy-related ubiquitin-like protein family
    360. Autophagy Controls Salmonella Infection in Response to Damage to the Salmonella-containing Vacuole
    361. Autophagy and metastasis: another double-edged sword
    362. Mitochondrial fusion, fission and Autophagy as a quality control axis: The bioenergetic view
    363. Postfertilization Autophagy of Sperm Organelles Prevents Paternal Mitochondrial DNA Transmission
    364. Apg7p/Cvt2p: A Novel Protein-activating Enzyme Essential for Autophagy
    365. Direct Induction of Autophagy by Atg1 Inhibits Cell Growth and Induces Apoptotic Cell Death
    366. Tor Directly Controls the Atg1 Kinase Complex To Regulate Autophagy
    367. Bacteria–Autophagy interplay: a battle for survival
    368. Autophagy in human type 2 diabetes pancreatic beta cells
    369. Autophagy, Metabolism, and Cancer
    370. Molecular definitions of Autophagy and related processes
    371. Autophagy genes and ageing
    372. Autophagy–physiology and pathophysiology
    373. Protective role of Autophagy in neonatal hypoxia–ischemia induced brain injury
    374. Neuronal Autophagy and neurodegenerative diseases
    375. Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
    376. Autophagy in Antimicrobial Immunity
    377. Induction of Autophagy in Axonal Dystrophy and Degeneration
    378. Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice
    379. The role of Autophagy-lysosome pathway in neurodegeneration associated with Parkinson’s disease
    380. Coronavirus Replication Complex Formation Utilizes Components of Cellular Autophagy
    381. The Autophagy effector Beclin 1: a novel BH3-only protein
    382. The Autophagy machinery is required to initiate hepatitis C virus replication
    383. Autophagy in tumour suppression and promotion
    384. Bcl-2 Inhibition of Autophagy: A New Route to Cancer?
    385. ESCRTs and Fab1 Regulate Distinct Steps of Autophagy
    386. FOXO3A directs a protective Autophagy program in haematopoietic stem cells
    387. Atg8‐family interacting motif crucial for selective Autophagy
    388. p53 status determines the role of Autophagy in pancreatic tumour development
    389. DNA damage and Autophagy
    390. Chaperone-mediated Autophagy: selectivity pays off
    391. Autophagy
    392. Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice
    393. microRNA‐101 is a potent inhibitor of Autophagy
    394. Nutrient-sensing nuclear receptors coordinate Autophagy
    395. A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans
    396. Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury
    397. Cytoplasmic bacteria can be targets for Autophagy
    398. The multiple roles of Autophagy in cancer
    399. Autophagy is a therapeutic target in anticancer drug resistance
    400. Regulation of the aging process by Autophagy
    401. Autophagy and cell death in model organisms
    402. The Autophagy protein Atg7 is essential for hematopoietic stem cell maintenance
    403. Autophagy Is Essential for Mitochondrial Clearance in Mature T Lymphocytes
    404. Image-based genome-wide siRNA screen identifies selective Autophagy factors
    405. Autophagy and Cancer Therapy
    406. PpAtg30 Tags Peroxisomes for Turnover by Selective Autophagy
    407. Absence of Autophagy results in reactive oxygen species-dependent amplification of RLR signaling
    408. Autophagy and human disease: emerging themes
    409. Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment
    410. Chemical modulators of Autophagy as biological probes and potential therapeutics
    411. Pathophysiology of chaperone-mediated Autophagy
    412. Regulation of endoplasmic reticulum turnover by selective Autophagy
    413. Autosis and autophagic cell death: the dark side of Autophagy
    414. The Role of Autophagy in Mammalian Development: Cell Makeover Rather than Cell Death
    415. Regulation of the Autophagy protein LC3 by phosphorylation
    416. Therapeutic targets in cancer cell metabolism and Autophagy
    417. Autophagy: Pathways for Self-Eating in Plant Cells
    418. An Autophagy–Enhancing Drug Promotes Degradation of Mutant α1-Antitrypsin Z and Reduces Hepatic Fibrosis
    419. Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase
    420. Mechanisms of Selective Autophagy
    421. Mechanisms of cross‐talk between the ubiquitin‐proteasome and Autophagy‐lysosome systems
    422. Chaperone-Mediated Autophagy
    423. A novel assay to study Autophagy: regulation of autophagosome vacuole size by amino acid deprivation
    424. Coordination of membrane events during Autophagy by multiple class III PI3-kinase complexes
    425. Molecular mechanism and regulation of Autophagy
    426. Induction of Autophagy by amino-acid deprivation in perfused rat liver
    427. Modulation of intracellular ROS levels by TIGAR controls Autophagy
    428. Mechanisms of Autophagy
    429. Cross talk between apoptosis and Autophagy by caspase-mediated cleavage of Beclin 1
    430. Autophagy Protects against Sindbis Virus Infection of the Central Nervous System
    431. Degradation of Oxidized Proteins by Autophagy during Oxidative Stress in Arabidopsis
    432. The Autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice
    433. Autophagy in immunity and cell‐autonomous defense against intracellular microbes
    434. The Reversible Modification Regulates the Membrane-Binding State of Apg8/Aut7 Essential for Autophagy and the Cytoplasm to Vacuole Targeting Pathway
    435. Overexpression of Atg5 in mice activates Autophagy and extends lifespan
    436. TAK1 activates AMPK‐dependent cytoprotective Autophagy in TRAIL‐treated epithelial cells
    437. Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
    438. Integration of Clearance Mechanisms: The Proteasome and Autophagy
    439. Role of Autophagy in suppression of inflammation and cancer
    440. Autophagy is an immediate macrophage response to Legionella pneumophila
    441. Stimulation of Autophagy by the p53 target gene Sestrin2
    442. Functional interaction between Autophagy and ciliogenesis
    443. Role of mitochondrial permeability transition pores in mitochondrial Autophagy
    444. Autophagy: An Emerging Immunological Paradigm
    445. MyD88 and Trif Target Beclin 1 to Trigger Autophagy in Macrophages
    446. The eIF2α/ATF4 pathway is essential for stress-induced Autophagy gene expression
    447. Ubiquitin-Dependent And Independent Signals In Selective Autophagy
    448. UPR, Autophagy, and mitochondria crosstalk underlies the ER stress response
    449. Regulation of Neuronal Survival Factor MEF2D by Chaperone-Mediated Autophagy
    450. Autophagy in Huntington disease and huntingtin in Autophagy
    451. Selective Autophagy in Cancer Development and Therapy
    452. Signalling and Autophagy regulation in health, aging and disease
    453. Autophagy in nonalcoholic steatohepatitis
    454. Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing Autophagy
    455. Extracellular matrix regulation of Autophagy
    456. HMGB1 release and redox regulates Autophagy and apoptosis in cancer cells
    457. Autophagy in the cardiovascular system
    458. Crosstalk Between Autophagy and Apoptosis in Heart Disease
    459. The anticancer drug imatinib induces cellular Autophagy
    460. Complex Inhibitory Effects of Nitric Oxide on Autophagy
    461. Initiation of apoptosis and Autophagy by photodynamic therapy
    462. Autophagy mediates degradation of nuclear lamina
    463. Role of LAMP-2 in Lysosome Biogenesis and Autophagy
    464. NBR1 and p62 as cargo receptors for selective Autophagy of ubiquitinated targets
    465. Mature ribosomes are selectively degraded upon starvation by an Autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease
    466. Linking of Autophagy to Ubiquitin-Proteasome System Is Important for the Regulation of Endoplasmic Reticulum Stress and Cell Viability
    467. Autophagy and cancer cell metabolism
    468. TFEB-mediated Autophagy rescues midbrain dopamine neurons from α-synuclein toxicity
    469. Crosstalk between apoptosis and Autophagy within the Beclin 1 interactome
    470. Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation
    471. Activation of Autophagy protects against acetaminophen‐induced hepatotoxicity
    472. Enhanced Autophagy ameliorates cardiac proteinopathy
    473. Following Autophagy step by step
    474. Akt inhibition promotes Autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
    475. Autophagy and the ubiquitin-proteasome system: Collaborators in neuroprotection
    476. Restoration of chaperone-mediated Autophagy in aging liver improves cellular maintenance and hepatic function
    477. Autophagy in cardiovascular disease
    478. Canonical and non-canonical Autophagy: variations on a common theme of self-eating?
    479. Approaching the Molecular Mechanism of Autophagy
    480. Does Autophagy have a license to kill mammalian cells?
    481. Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease
    482. Generation of cell lines with tetracycline‐regulated Autophagy and a role for Autophagy in controlling cell size
    483. Chaperone-mediated Autophagy at a glance
    484. Efficient Cross-presentation Depends on Autophagy in Tumor Cells
    485. Autophagy: Regulation and role in disease
    486. Atg17 Functions in Cooperation with Atg1 and Atg13 in Yeast Autophagy
    487. Autophagy in cardiac myocyte homeostasis, aging, and pathology
    488. Autophagy, Cytoplasm-to-Vacuole Targeting Pathway, and Pexophagy in Yeast and Mammalian Cells
    489. Autophagy Is Activated by Apoptotic Signalling in Sympathetic Neurons: An Alternative Mechanism of Death Execution
    490. A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62
    491. TBK-1 Promotes Autophagy–Mediated Antimicrobial Defense by Controlling Autophagosome Maturation
    492. Role of Autophagy in G2019S‐LRRK2‐associated neurite shortening in differentiated SH‐SY5Y cells
    493. Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication
    494. Ammonia-induced Autophagy is independent of ULK1/ULK2 kinases
    495. Autophagy, a guardian against neurodegeneration
    496. Autophagy Contributes to Caspase-independent Macrophage Cell Death
    497. Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet
    498. Autophagy in cardiovascular biology
    499. Autophagy: machinery and regulation
    500. Mammalian Autophagy: How Does It Work?
    501. Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L
    502. Autophagy in proximal tubules protects against acute kidney injury
    503. Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy
    504. Aggresomes and Autophagy Generate Sites for Virus Replication
    505. Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages
    506. Autophagy and adaptive immunity
    507. Synergistic Augmentation of Rapamycin-Induced Autophagy in Malignant Glioma Cells by Phosphatidylinositol 3-Kinase/Protein Kinase B Inhibitors
    508. Postischemic treatment of neonatal cerebral ischemia should target Autophagy
    509. Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway
    510. p65/RelA Modulates BECN1 Transcription and Autophagy
    511. Autophagy in health and disease. 1. Regulation and significance of Autophagy: an overview
    512. Plasma cells require Autophagy for sustainable immunoglobulin production
    513. Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3
    514. Glucocorticoid‐induced Autophagy in osteocytes
    515. An Atg1/Atg13 Complex with Multiple Roles in TOR-mediated Autophagy Regulation
    516. Eating the endoplasmic reticulum: quality control by Autophagy
    517. Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages
    518. siRNA Screening of the Kinome Identifies ULK1 as a Multidomain Modulator of Autophagy
    519. Autophagy and Tumorigenesis
    520. Chaperone-mediated Autophagy: Molecular mechanisms and physiological relevance
    521. Cytosolic FoxO1 is essential for the induction of Autophagy and tumour suppressor activity
    522. Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway
    523. Autophagy activation by rapamycin reduces severity of experimental osteoarthritis
    524. A New Protein Conjugation System in Human
      THE COUNTERPART OF THE YEAST Apg12p CONJUGATION SYSTEM ESSENTIAL FOR Autophagy
    525. Role of Mitochondrial Inner Membrane Permeabilization in Necrotic Cell Death, Apoptosis, and Autophagy
    526. Mutant p53 protein localized in the cytoplasm inhibits Autophagy
    527. SIRT1: Regulation of longevity via Autophagy
    528. Autophagy, Not Apoptosis, Is Essential for Midgut Cell Death in Drosophila
    529. Regulation of Autophagy by mTOR-dependent and mTOR-independent pathways: Autophagy dysfunction in neurodegenerative diseases and therapeutic application of Autophagy enhancers
    530. Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function
    531. Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy
    532. Control of Autophagy initiation by phosphoinositide 3‐phosphatase jumpy
    533. Degradation of Paternal Mitochondria by Fertilization-Triggered Autophagy in C. elegans Embryos
    534. How to Live Long and Prosper: Autophagy, Mitochondria, and Aging
    535. Autophagy Is an Essential Component of Drosophila Immunity against Vesicular Stomatitis Virus
    536. Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic Autophagy deficiency
    537. Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells
    538. Rapamycin protects against rotenone-induced apoptosis through Autophagy induction
    539. Proteases in Autophagy
    540. Adipose-specific deletion of Autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
    541. The Four Faces of Autophagy: Implications for Cancer Therapy
    542. Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by Autophagy
    543. Autophagy Signaling Through Reactive Oxygen Species
    544. PARTICIPATION OF LYSOSOMES IN CELLULAR Autophagy INDUCED IN RAT LIVER BY GLUCAGON
    545. Autophagy for tissue homeostasis and neuroprotection
    546. Molecules and their functions in Autophagy
    547. Aβ Secretion and Plaque Formation Depend on Autophagy
    548. Structural basis of target recognition by Atg8/LC3 during selective Autophagy
    549. Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration
    550. Metformin inhibits melanoma development through Autophagy and apoptosis mechanisms
    551. Altered Autophagy in Human Adipose Tissues in Obesity
    552. Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation
    553. Aggregate‐Prone Proteins Are Cleared from the Cytosol by Autophagy: Therapeutic Implications
    554. MicroRNAs in apoptosis, Autophagy and necroptosis
    555. Relationship between the proteasomal system and Autophagy
    556. Rapamycin and mTOR-independent Autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
    557. Autophagy Induction by the Pathogen Receptor CD46
    558. PUMA- and Bax-induced Autophagy contributes to apoptosis
    559. Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption
    560. mTORC1 Phosphorylates the ULK1-mAtg13-FIP200 Autophagy Regulatory Complex
    561. Eating the enemy within: Autophagy in infectious diseases
    562. INFLUENCE OF GLUCAGON, AN INDUCER OF CELLULAR Autophagy, ON SOME PHYSICAL PROPERTIES OF RAT LIVER LYSOSOMES
    563. Downregulated MEG3 activates Autophagy and increases cell proliferation in bladder cancer
    564. Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest
    565. Regulation of Autophagy by the p300 Acetyltransferase
    566. GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation
    567. Keap1 degradation by Autophagy for the maintenance of redox homeostasis
    568. Viruses and the Autophagy machinery
    569. Autophagy: molecular mechanisms, physiological functions and relevance in human pathology
    570. Essential role for Autophagy in life span extension
    571. Targeting Autophagy Addiction in Cancer
    572. p62, an Autophagy hero or culprit?
    573. Autophagy in Yeast: ATOR-Mediated Response to Nutrient Starvation
    574. The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation
    575. BNIP3 Is an RB/E2F Target Gene Required for Hypoxia-Induced Autophagy
    576. The unfolded protein response protects human tumor cells during hypoxia through regulation of the Autophagy genes MAP1LC3B and ATG5
    577. p53/HMGB1 Complexes Regulate Autophagy and Apoptosis
    578. The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian Autophagy
    579. Valosin-containing protein (VCP) is required for Autophagy and is disrupted in VCP disease
    580. Autophagy in Load-Induced Heart Disease
    581. To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate
    582. Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and MacroAutophagy in Neuronal Cells
    583. Protein breakdown in muscle wasting: Role of Autophagy-lysosome and ubiquitin-proteasome
    584. Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
    585. How do ESCRT proteins control Autophagy?
    586. Resveratrol-Activated AMPK/SIRT1/Autophagy in Cellular Models of Parkinson’s Disease
    587. Autophagy: a multifaceted intracellular system for bulk and selective recycling
    588. Autophagy promotes synapse development in Drosophila
    589. Autophagy, proteasomes, lipofuscin, and oxidative stress in the aging brain
    590. Spermidine and resveratrol induce Autophagy by distinct pathways converging on the acetylproteome
    591. Noncanonical Autophagy Promotes the Visual Cycle
    592. Regulation of Autophagy by ATF4 in response to severe hypoxia
    593. C. elegans Screen Identifies Autophagy Genes Specific to Multicellular Organisms
    594. Chapter 10 Monitoring Autophagy by Electron Microscopy in Mammalian Cells
    595. Glycogen Autophagy in glucose homeostasis
    596. mTOR inhibits Autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6
    597. The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte Autophagy
    598. XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing Autophagy
    599. Autophagy in cellular growth control
    600. Suppression of Autophagy by FIP200 deletion inhibits mammary tumorigenesis
    601. AMPK and Autophagy get connected
    602. Processing of ATG8s, Ubiquitin-Like Proteins, and Their Deconjugation by ATG4s Are Essential for Plant Autophagy
    603. Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A
    604. Transcriptional control of Autophagy–lysosome function drives pancreatic cancer metabolism
    605. Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn’s Disease Associated ATG16L1 Variant
    606. Mycobacterium tuberculosis inhibition of phagolysosome biogenesis and Autophagy as a host defence mechanism
    607. The return of the nucleus: transcriptional and epigenetic control of Autophagy
    608. Autophagy and disease: always two sides to a problem
    609. Early endosomes and endosomal coatomer are required for Autophagy
    610. A role for Autophagy during hepatic stellate cell activation
    611. Autophagy in Yeast: Mechanistic Insights and Physiological Function
    612. Apg16p is required for the function of the Apg12p–Apg5p conjugate in the yeast Autophagy pathway
    613. Nonselective Autophagy of cytosolic enzymes by isolated rat hepatocytes.
    614. Autophagy Is Required for Maintenance of Amino Acid Levels and Protein Synthesis under Nitrogen Starvation
    615. Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase
    616. Identification of Barkor as a mammalian Autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase
    617. HDACs link the DNA damage response, processing of double-strand breaks and Autophagy
    618. Autophagy and Cancer
    619. Autophagy—a key player in cellular and body metabolism
    620. Sirtuins’ modulation of Autophagy
    621. Tumor Vessel Normalization by Chloroquine Independent of Autophagy
    622. Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities
    623. Autophagy in neurodegeneration and development
    624. The Cvt pathway as a model for selective Autophagy
    625. Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4
    626. Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma
    627. Regulation of Autophagy by Extracellular Signal-Regulated Protein Kinases During 1-Methyl-4-Phenylpyridinium-Induced Cell Death
    628. Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury
    629. Autophagy: links with the proteasome
    630. The crosstalk between Autophagy and apoptosis: where does this lead?
    631. Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury
    632. The tumor suppressor gene ARHI regulates Autophagy and tumor dormancy in human ovarian cancer cells
    633. Autophagy and Tumor Metabolism
    634. Essential role for Autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration
    635. Autophagy in Protein and Organelle Turnover
    636. Sphingolipids: regulators of crosstalk between apoptosis and Autophagy
    637. HMGB1-induced Autophagy promotes chemotherapy resistance in leukemia cells
    638. Regulation of Autophagy by phosphatidylinositol 3-phosphate
    639. Focal cerebral ischemia induces upregulation of Beclin 1 and Autophagy–like cell death
    640. Programmed Autophagy in the Drosophila Fat Body Is Induced by Ecdysone through Regulation of the PI3K Pathway
    641. Akt and Autophagy Cooperate to Promote Survival of Drug-Resistant Glioma
    642. Autophagy in filamentous fungi
    643. Intracellular Protein Aggregation Is a Proximal Trigger of Cardiomyocyte Autophagy
    644. Regulation of innate immune responses by Autophagy-related proteins
    645. Participation of Autophagy in renal ischemia/reperfusion injury
    646. Ubiquilin functions in Autophagy and is degraded by chaperone-mediated Autophagy
    647. Structural Aspects of Autophagy
    648. Chapter 1 Monitoring Autophagy in Mammalian Cultured Cells through the Dynamics of LC3
    649. Ammonia Derived from Glutaminolysis Is a Diffusible Regulator of Autophagy
    650. Autophagy proteins regulate ERK phosphorylation
    651. Autophagy in cancer metastasis
    652. GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy
    653. Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells
    654. Targeting Autophagy potentiates tyrosine kinase inhibitor–induced cell death in Philadelphia chromosome–positive cells, including primary CML stem cells
    655. Function and Molecular Mechanism of Acetylation in Autophagy Regulation
    656. Digesting the Expanding Mechanisms of Autophagy
    657. Autophagy—A double‐edged sword in oncology
    658. The dual role of Autophagy in cancer
    659. Emerging Role for Autophagy in the Removal of Aggresomes in Schwann Cells
    660. A Salmonella protein causes macrophage cell death by inducing Autophagy
    661. Recycle or die: The role of Autophagy in cardioprotection
    662. Autophagy in Atherosclerosis
    663. Autophagy is an adaptive response in desmin-related cardiomyopathy
    664. Autophagy in Diabetic Nephropathy
    665. Major histocompatibility complex class II‐restricted presentation of a cytosolic antigen by Autophagy
    666. Autophagy Is Activated in Colorectal Cancer Cells and Contributes to the Tolerance to Nutrient Deprivation
    667. Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens
    668. Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection
    669. Autophagy in Vascular Disease
    670. Targeting Autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl–mediated drug resistance
    671. Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial Autophagy in mouse aged kidney
    672. Autophagy contributes to resistance of tumor cells to ionizing radiation
    673. EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance
    674. Development of Autophagy inducers in clinical medicine
    675. Role of Autophagy in Cancer Prevention
    676. Methamphetamine-Induced Degeneration of Dopaminergic Neurons Involves Autophagy and Upregulation of Dopamine Synthesis
    677. Peroxisome turnover by micropexophagy: an Autophagy-related process
    678. In Situ Detection of Starvation-induced Autophagy
    679. Autophagy in Hypothalamic AgRP Neurons Regulates Food Intake and Energy Balance
    680. Bcl-2:Beclin 1 complex: multiple, mechanisms regulating Autophagy/apoptosis toggle switch
    681. Receptor-mediated selective Autophagy degrades the endoplasmic reticulum and the nucleus
    682. Diet, Autophagy, and Cancer: A Review
    683. A dual role for Ca2+ in Autophagy regulation
    684. Autophagy and antiviral immunity
    685. p62/SQSTM1 functions as a signaling hub and an Autophagy adaptor
    686. Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes
    687. Protein and mRNA expression of Autophagy gene Beclin 1 in human brain tumours
    688. Methods for Assessing Autophagy and Autophagic Cell Death
    689. Constitutive Activation of Chaperone-mediated Autophagy in Cells with Impaired MacroAutophagy
    690. Regulation of lipid droplets by Autophagy
    691. Autophagy in cardiac myocytes.
    692. Membrane Recruitment of Aut7p in the Autophagy and Cytoplasm to Vacuole Targeting Pathways Requires Aut1p, Aut2p, and the Autophagy Conjugation Complex
    693. Increased Autophagy in transgenic mice with a G93A mutant SOD1 gene
    694. p38 and JNK MAPK pathways control the balance of apoptosis and Autophagy in response to chemotherapeutic agents
    695. Huntington’s disease: degradation of mutant huntingtin by Autophagy
    696. Autophagy modulation for cancer therapy
    697. Atg5: more than an Autophagy factor
    698. Apoptosis and Autophagy: Targeting Autophagy signallingin cancer cells – ‘trick or treats’?
    699. DAP‐kinase‐mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl‐XL and induction of Autophagy
    700. Negative regulation of Autophagy
    701. Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling
    702. Journal of the American College of Cardiology
    703. Autophagy regulates TNFα-mediated joint destruction in experimental arthritis
    704. Cholesterol depletion induces Autophagy
    705. Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol
    706. Remodeling the Endoplasmic Reticulum by Poliovirus Infection and by Individual Viral Proteins: an Autophagy-Like Origin for Virus-Induced Vesicles
    707. Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via Autophagy enhancement
    708. Genetic and Phenotypic Overlap between Autophagy and the Cytoplasm to Vacuole Protein Targeting Pathway
    709. JNK regulates FoxO-dependent Autophagy in neurons
    710. Deacetylation of Nuclear LC3 Drives Autophagy Initiation under Starvation
    711. DNA damaging agent-induced Autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells
    712. Autophagy, plant senescence, and nutrient recycling
    713. Guidelines for the use and interpretation of assays for monitoring Autophagy
    714. p62 links Autophagy and Nrf2 signaling
    715. Non‐autophagic roles of Autophagy‐related proteins
    716. Autophagy in atherosclerosis
    717. Autophagy and pancreatitis
    718. Radiation-induced Autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells
    719. Dual roles of Autophagy in the survival of Caenorhabditis elegans during starvation
    720. Transcriptional regulation of Autophagy by an FXR–CREB axis
    721. Autophagy and neurodegeneration
    722. Autophagy Plays a Role in Chloroplast Degradation during Senescence in Individually Darkened Leaves
    723. Structure of Atg5·Atg16, a Complex Essential for Autophagy
    724. Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night
    725. mTOR and Autophagy: A dynamic relationship governed by nutrients and energy
    726. TOR-dependent control of Autophagy: biting the hand that feeds
    727. Starving Neurons Show Sex Difference in Autophagy
    728. Targeting ER stress–induced Autophagy overcomes BRAF inhibitor resistance in melanoma
    729. Starvation‐induced expression of Autophagy‐related genes in Arabidopsis
    730. Involvement of Autophagy in trypsinogen activation within the pancreatic acinar cells
    731. ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms
    732. The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane
    733. BAG3 mediates chaperone‐based aggresome‐targeting and selective Autophagy of misfolded proteins
    734. The Role of Lipids in the Control of Autophagy
    735. mTOR’s role in ageing: protein synthesis or Autophagy?
    736. Hepatitis C Virus Genotype 1a Growth and Induction of Autophagy
    737. Selective types of Autophagy in yeast
    738. The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes Autophagy
    739. Regulation of Autophagy by the Rab GTPase network
    740. Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
    741. Bcl‐2 and Bcl‐xL play important roles in the crosstalk between Autophagy and apoptosis
    742. Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease
    743. Autophagy Releases Lipid That Promotes Fibrogenesis by Activated Hepatic Stellate Cells in Mice and in Human Tissues
    744. Inhibition of Autophagy in Mitotic Animal Cells
    745. Crohn’s disease: NOD2, Autophagy and ER stress converge
    746. Autophagy and inflammatory diseases
    747. Autophagy
    748. Regulation of Autophagy by stress-responsive transcription factors
    749. Dengue Virus and Autophagy
    750. Analyses of APG13 gene involved in Autophagy in yeast, Saccharomyces cerevisiae
    751. The Impact of Autophagy on Cell Death Modalities
    752. Regulation of Autophagy in mammals and its interplay with apoptosis
    753. Aging: Central role for Autophagy and the lysosomal degradative system
    754. Autophagy and the degradation of mitochondria
    755. Dependence of hepatocytic Autophagy on intracellularly sequestered calcium.
    756. Autophagy in Innate Immunity against Intracellular Bacteria
    757. Autophagy: Role in surviving environmental stress
    758. Autophagy: Is It Cancer’s Friend or Foe?
    759. Autophagy and Its Role in MHC-Mediated Antigen Presentation
    760. Autophagy and genomic integrity
    761. Autophagy induction favours the generation and maturation of the Coxiella‐replicative vacuoles
    762. Autophagy and p62 in Cardiac Proteinopathy
    763. Ordered Organelle Degradation during Starvation-induced Autophagy
    764. Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment
    765. AMPK-Dependent Phosphorylation of ULK1 Induces Autophagy
    766. Autophagy: shaping the tumor microenvironment and therapeutic response
    767. Autophagy in the Lung
    768. Autophagy and antigen presentation
    769. Atg7-dependent Autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophil
    770. DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and Autophagy
    771. The induction of Autophagy by γ‐radiation contributes to the radioresistance of glioma stem cells
    772. Apoptosis and Autophagy: Regulation of caspase‐9 by phosphorylation
    773. TRAF6 and A20 Regulate Lysine 63–Linked Ubiquitination of Beclin-1 to Control TLR4-Induced Autophagy
    774. Autophagy regulation and its role in cancer
    775. Role of non-canonical Beclin 1-independent Autophagy in cell death induced by resveratrol in human breast cancer cells
    776. Methods for detecting Autophagy and determining Autophagy–induced cell death
    777. Formation of the ∼350-kDa Apg12-Apg5·Apg16 Multimeric Complex, Mediated by Apg16 Oligomerization, Is Essential for Autophagy in Yeast
    778. Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications
    779. ER stress–mediated Autophagy promotes Myc-dependent transformation and tumor growth
    780. AMPK‐mediated Autophagy inhibits apoptosis in cisplatin‐treated tumour cells
    781. Atg22 Recycles Amino Acids to Link the Degradative and Recycling Functions of Autophagy
    782. Autophagy Induced by Ischemic Preconditioning is Essential for Cardioprotection
    783. Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes
    784. Autophagy as a therapeutic target in cardiovascular disease
    785. Proteasome inhibitors activate Autophagy as a cytoprotective response in human prostate cancer cells
    786. Induction of Autophagy Promotes Fusion of Multivesicular Bodies with Autophagic Vacuoles in K562 Cells
    787. Oxidative Stress, Redox Signaling, and Autophagy: Cell Death Versus Survival
    788. A Non-canonical MEK/ERK Signaling Pathway Regulates Autophagy via Regulating Beclin 1
    789. Alpha-alumina nanoparticles induce efficient Autophagy-dependent cross-presentation and potent antitumour response
    790. Application and interpretation of current Autophagy inhibitors and activators
    791. Modification of Cellular Autophagy Protein LC3 by Poliovirus
    792. Inactivation of the Autophagy Gene bec-1 Triggers Apoptotic Cell Death in C. elegans
    793. Autophagy in cellular metabolism and cancer
    794. Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease
    795. Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance
    796. Induction of ROS, mitochondrial damage and Autophagy in lung epithelial cancer cells by iron oxide nanoparticles
    797. Chaperone-mediated Autophagy in health and disease
    798. Autophagy in health and disease. 3. Involvement of Autophagy in muscle atrophy
    799. Oxidative stress and Autophagy in cardiac disease, neurological disorders, aging and cancer
    800. Selective types of Autophagy
    801. Selective Autophagy
    802. Autophagy is required for necrotic cell death in Caenorhabditis elegans
    803. Dopamine Oxidation and Autophagy
    804. Autophagy: Paying Charon’s Toll
    805. Self and Nonself: How Autophagy Targets Mitochondria and Bacteria
    806. Autophagy as a cell-repair mechanism: Activation of chaperone-mediated Autophagy during oxidative stress
    807. Mutant A53T α-Synuclein Induces Neuronal Death by Increasing Mitochondrial Autophagy
    808. Connections between SNAREs and Autophagy
    809. Emerging strategies to effectively target Autophagy in cancer
    810. Pharmacological modulation of Autophagy: therapeutic potential and persisting obstacles
    811. Guidelines for the use and interpretation of assays for monitoring Autophagy in higher eukaryotes
    812. The endoplasmic reticulum in apoptosis and Autophagy: role of the BCL-2 protein family
    813. Autophagy, polyphenols and healthy ageing
    814. Autophagy in neuroprotection and neurodegeneration: a question of balance
    815. Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote Autophagy
    816. Hypoxia signals Autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L
    817. The role of autophagy in tumour development and cancer therapy
    818. Autophagy in cutaneous malignant melanoma
    819. Sulforaphane Causes Autophagy to Inhibit Release of Cytochrome c and Apoptosis in Human Prostate Cancer Cells
    820. Ceramides and other bioactive sphingolipid backbones in health and disease: Lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and Autophagy
    821. Toll-like receptors in control of immunological Autophagy
    822. Protein Kinase A and Sch9 Cooperatively Regulate Induction of Autophagy in Saccharomyces cerevisiae
    823. Selective Autophagy in budding yeast
    824. Class III PI3K Vps34 plays an essential role in Autophagy and in heart and liver function
    825. Small molecule enhancers of Autophagy for neurodegenerative diseases
    826. Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth
    827. Autophagy and mitophagy in cellular damage control
    828. Chaperone-Mediated Autophagy
    829. Organelle-Specific Initiation of Autophagy
    830. Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced Autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria
    831. Autophagy in Drosophila melanogaster
    832. Guidelines for the use and interpretation of assays for monitoring Autophagy (3rd edition)
    833. Membrane Origin for Autophagy
    834. Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors
    835. Association of Autophagy Defect with a Malignant Phenotype and Poor Prognosis of Hepatocellular Carcinoma
    836. Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for Autophagy
    837. Toward unraveling membrane biogenesis in mammalian Autophagy
    838. Mechanisms of Autophagy Initiation
    839. All-you-can-eat: Autophagy in neurodegeneration and neuroprotection
    840. A Novel Protein Complex Linking the δ2 Glutamate Receptor and Autophagy: Implications for Neurodegeneration in Lurcher Mice
    841. Apg9p/Cvt7p Is an Integral Membrane Protein Required for Transport Vesicle Formation in the Cvt and Autophagy Pathways
    842. Apg14p and Apg6/Vps30p Form a Protein Complex Essential for Autophagy in the Yeast, Saccharomyces cerevisiae
    843. The class III PI(3)K Vps34 promotes Autophagy and endocytosis but not TOR signaling in Drosophila
    844. Life, death and burial: multifaceted impact of Autophagy
    845. Glycogen Autophagy
    846. Autophagy in human tumors: cell survival or death?
    847. Quantum Dots for Human Mesenchymal Stem Cells Labeling. A Size-Dependent Autophagy Activation
    848. Autophagy and cancer – issues we need to digest
    849. Feedback on Fat: p62-mTORC1-Autophagy Connections
    850. Monitoring and Measuring Autophagy
    851. Nutrient-dependent regulation of Autophagy through the target of rapamycin pathway
    852. Neuronal Autophagy in experimental scrapie
    853. Autophagy promotes necrosis in apoptosis-deficient cells in response to ER stress
    854. Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy
    855. Human IRGM regulates Autophagy and cell-autonomous immunity functions through mitochondria
    856. Role of the Apg12 conjugation system in mammalian Autophagy
    857. Autophagy in C. elegans
    858. Prorenin Receptor Is Essential for Podocyte Autophagy and Survival
    859. Autophagy after Experimental Intracerebral Hemorrhage
    860. ZKSCAN3 Is a Master Transcriptional Repressor of Autophagy
    861. Autophagy, Apoptosis, Mitoptosis and Necrosis: Interdependence Between Those Pathways and Effects on Cancer
    862. Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming
    863. Targeting Autophagy in neurodegenerative diseases
    864. Identification of Regulators of Chaperone-Mediated Autophagy
    865. Runx1 prevents wasting, myofibrillar disorganization, and Autophagy of skeletal muscle
    866. Autophagy and cell death
    867. Autophagy in aging, disease and death: the true identity of a cell death impostor
    868. Autophagy Contributes to Leaf Starch Degradation
    869. Targeting Autophagy during cancer therapy to improve clinical outcomes
    870. Autophagy: More Than a Nonselective Pathway
    871. Immunologic manifestations of Autophagy
    872. Azithromycin blocks Autophagy and may predispose cystic fibrosis patients to mycobacterial infection
    873. Cellular and metabolic functions for Autophagy in cancer cells
    874. Autophagy as a pro‐death pathway
    875. Mitochondria regulate Autophagy by conserved signalling pathways
    876. Autophagy in Vascular Disease
    877. Autophagy: a druggable process that is deregulated in aging and human disease
    878. The regulation of aging: does Autophagy underlie longevity?
    879. Turnover of organelles by Autophagy in yeast
    880. Autophagy is a protective mechanism in normal cartilage, and its aging‐related loss is linked with cell death and osteoarthritis
    881. Cleaning House: Selective Autophagy of Organelles
    882. Therapeutic Targeting of Autophagy
    883. Interactions of Pathogenic Bacteria with Autophagy Systems
    884. PLIC proteins or ubiquilins regulate Autophagy‐dependent cell survival during nutrient starvation
    885. Autophagy proteins in macroendocytic engulfment
    886. Constitutive Autophagy: vital role in clearance of unfavorable proteins in neurons
    887. Endocytosis and Autophagy: Shared machinery for degradation
    888. Autophagy regulates selective HMGB1 release in tumor cells that are destined to die
    889. Autophagy in organelle homeostasis: Peroxisome turnover
    890. Regulation of Autophagy in human and murine cartilage: Hypoxia‐inducible factor 2 suppresses chondrocyte Autophagy
    891. Inhibition of Autophagy abrogates tumour necrosis factor α induced apoptosis in human T‐lymphoblastic leukaemic cells
    892. Autophagy as a target for cancer therapy: new developments
    893. Hypoxia-activated Autophagy accelerates degradation of SQSTM1/p62
    894. The role of PI3K/AKT/mTOR pathway in the modulation of Autophagy and the clearance of protein aggregates in neurodegeneration
    895. Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance
    896. The molecular mechanism of mitochondria Autophagy in yeast
    897. Reversal of Autophagy dysfunction in the TgCRND8 mouse model of Alzheimer’s disease ameliorates amyloid pathologies and memory deficits
    898. Induction of Autophagy is essential for monocyte-macrophage differentiation
    899. Autophagy takes flight inDrosophila
    900. Chapter 2 Methods for Monitoring Autophagy Using GFP‐LC3 Transgenic Mice
    901. Induction of Autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance
    902. Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts
    903. Autophagy Negatively Regulates Cell Death by Controlling NPR1-Dependent Salicylic Acid Signaling during Senescence and the Innate Immune Response in Arabidopsis
    904. Autophagy and ethanol-induced liver injury
    905. Autophagy and mitophagy in diabetic cardiomyopathy
    906. Metabolic Stress in Autophagy and Cell Death Pathways
    907. Autophagy in disease: a double-edged sword with therapeutic potential
    908. Autophagy as a mediator of chemotherapy-induced cell death in cancer
    909. AMPK-independent induction of Autophagy by cytosolic Ca2+ increase
    910. Autophagy regulates inflammation in adipocytes
    911. Autophagy: molecular machinery, regulation, and implications for renal pathophysiology
    912. Expression of beclin‐1, an Autophagy‐related protein, in gastric and colorectal cancers
    913. CD40 induces macrophage anti–Toxoplasma gondii activity by triggering Autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes
    914. Autophagy and misfolded proteins in neurodegeneration
    915. The late stages of Autophagy: how does the end begin?
    916. Autophagy Regulates Endoplasmic Reticulum Homeostasis and Calcium Mobilization in T Lymphocytes
    917. Cadmium-induced Autophagy and apoptosis are mediated by a calcium signaling pathway
    918. The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib
    919. Autophagy and bacterial infectious diseases
    920. Autophagy in Atherosclerosis
    921. Autophagy and Viruses: Adversaries or Allies?
    922. Mitochondrial Autophagy and injury in the liver in α1-antitrypsin deficiency
    923. TOR Is a Negative Regulator of Autophagy in Arabidopsis thaliana
    924. Steroid‐triggered death by Autophagy
    925. Autophagy, the Trojan horse to combat glioblastomas
    926. Inhibition of Autophagy by 3-MA Enhances the Effect of 5-FU-Induced Apoptosis in Colon Cancer Cells
    927. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of Autophagy during lumen formation in vitro
    928. Endosome Sorting and Autophagy Are Essential for Differentiation and Virulence of Leishmania major
    929. Mechanism and medical implications of mammalian Autophagy
    930. Cell death and Autophagy: Cytokines, drugs, and nutritional factors
    931. Endogenous Drp1 Mediates Mitochondrial Autophagy and Protects the Heart Against Energy Stress
    932. Quantitative relationship between Autophagy and proteolysis during graded amino acid deprivation in perfused rat liver.
    933. Organellophagy: Eliminating cellular building blocks via selective Autophagy
    934. Chapter 3 The Quantitative Pho8Δ60 Assay of Nonspecific Autophagy
    935. Atomistic Autophagy: The Structures of Cellular Self-Digestion
    936. The IP3 receptor–mitochondria connection in apoptosis and Autophagy
    937. Nutrient Sensing, Autophagy, and Diabetic Nephropathy
    938. Aging and Autophagy in the Heart
    939. Arginine Deiminase as a Novel Therapy for Prostate Cancer Induces Autophagy and Caspase-Independent Apoptosis
    940. Autophagy in health and disease. 2. Regulation of lipid metabolism and storage by Autophagy: pathophysiological implications
    941. Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA
    942. Autophagy, cell death, and cancer
    943. Autophagy and endocrine resistance in breast cancer
    944. Autophagy in MHC class II antigen processing
    945. At the end of the autophagic road: an emerging understanding of lysosomal functions in Autophagy
    946. Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy
    947. Targeting cancer cells through Autophagy for anticancer therapy
    948. Autophagy failure in Alzheimer’s disease and the role of defective lysosomal acidification
    949. Subversion of cellular Autophagy by Anaplasma phagocytophilum
    950. Autophagy as a new therapeutic target in Duchenne muscular dystrophy
    951. Autophagy and viral neurovirulence
    952. The Role of the Selective Adaptor p62 and Ubiquitin-Like Proteins in Autophagy
    953. Leucine-rich repeat kinase 2 regulates Autophagy through a calcium-dependent pathway involving NAADP
    954. Autophagy – An Emerging Anti-Aging Mechanism
    955. Autophagy in Pulmonary Diseases
    956. Tau degradation: The ubiquitin–proteasome system versus the Autophagy-lysosome system
    957. Degradation of lipid droplet-associated proteins by chaperone-mediated Autophagy facilitates lipolysis
    958. Review: Autophagy in neurodegeneration: firefighter and/or incendiarist?
    959. Chikungunya virus–induced Autophagy delays caspase-dependent cell death
    960. Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema
    961. Accelerated Cell Death in Podospora Autophagy Mutants
    962. Multiple regulatory and effector roles of Autophagy in immunity
    963. Chaperone-mediated Autophagy: machinery, regulation and biological consequences
    964. ANG II promotes Autophagy in podocytes
    965. Protective Role of Autophagy in Palmitate-Induced INS-1 β-Cell Death
    966. Midbody ring disposal by Autophagy is a post-abscission event of cytokinesis
    967. Autophagy in the immune system
    968. Cardioprotection by Endoplasmic Reticulum Stress–Induced Autophagy
    969. MiR-30-Regulated Autophagy Mediates Angiotensin II-Induced Myocardial Hypertrophy
    970. Chapter 19 Methods to Monitor Chaperone‐Mediated Autophagy
    971. MAPK/JNK signalling: a potential Autophagy regulation pathway
    972. Mitochondrial Ca2+ signals in Autophagy
    973. Regulation and Function of Autophagy during Cell Survival and Cell Death
    974. Autophagy inhibitors
    975. Free Radicals in Cross Talk Between Autophagy and Apoptosis
    976. Autophagy Preceded Apoptosis in Oridonin-Treated Human Breast Cancer MCF-7 Cells
    977. Autophagy in hypoxia-ischemia induced brain injury
    978. Autophagy in intracellular bacterial infection
    979. Autophagy in unicellular eukaryotes
    980. Evidence That Curcumin Suppresses the Growth of Malignant Gliomas in Vitro and in Vivo through Induction of Autophagy: Role of Akt and Extracellular Signal-Regulated Kinase Signaling Pathways
    981. Autophagy and innate immunity: Triggering, targeting and tuning
    982. Autophagy is essential for effector CD8+ T cell survival and memory formation
    983. Molecular Mechanisms of Autophagy in the Cardiovascular System
    984. Cytotoxic Autophagy in Cancer Therapy
    985. TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the Autophagy/multivesicular body pathways
    986. New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and Autophagy
    987. The cell biology of Autophagy in metazoans: a developing story
    988. Understanding Autophagy in Cell Death Control
    989. The receptor for advanced glycation end products (RAGE) sustains Autophagy and limits apoptosis, promoting pancreatic tumor cell survival
    990. Erk1/2-dependent Phosphorylation of Gα-interacting Protein Stimulates Its GTPase Accelerating Activity and Autophagy in Human Colon Cancer Cells
    991. Autophagy in innate and adaptive immunity against intracellular pathogens
    992. Regulation of Liver Metabolism by Autophagy
    993. Author Correction: Autophagy maintains tumour growth through circulating arginine.
    994. Biological Functions of Autophagy Genes: A Disease Perspective
    995. RNA binding to p62 impacts selective Autophagy
    996. Intersections between Regulated Cell Death and Autophagy
    997. Ubiquitination of MAP1LC3B by pVHL is associated with Autophagy and cell death in renal cell carcinoma
    998. Autophagy without conjugation
    999. Chapter 16 – Autophagy and Autoimmunity
    1000. Autophagy in the Heart
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