Icariin
January 16, 2020Gossypol
January 17, 2020
- Exercise prevents diet-induced cellular senescence in adipose tissue
- Physiological aging: links among adipose tissue dysfunction, diabetes, and frailty
- Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses
- Aging and adipose tissue: potential interventions for diabetes and regenerative medicine
- Roles of chemokine ligand-2 (CXCL2) and neutrophils in influencing endothelial cell function and inflammation of human adipose tissue
- Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities
- The emerging role of senescent cells in tissue homeostasis and pathophysiology
- Cellular senescence and the senescent secretory phenotype in age-related chronic diseases
- JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
- Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice
- Aging-related inflammation in osteoarthritis
- Cellular senescence in type 2 diabetes: a therapeutic opportunity
- The fat cell senescence hypothesis: a mechanism responsible for abrogating the resolution of inflammation in chronic disease
- Feast and famine: adipose tissue adaptations for healthy aging
- Macrophages in age-related chronic inflammatory diseases
- Proposed metabolic vicious circle in patients with large myocardial infarcts and high plasma-free-fatty-acid concentrations
- Perspective: targeting the JAK/STAT pathway to fight age-related dysfunction
- Effect of low-dose rapamycin on senescence markers and physical functioning in older adults with coronary artery disease: results of a pilot study.
- Systemic DNA damage response and metabolic syndrome as a premalignant state
- Stem cell senescence and regenerative paradigms
- Cellular senescence in ageing, age-related disease and longevity
- Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus
- Phytochemicals suppress nuclear factor-κB signaling: impact on health span and the aging process
- Effect of lipopolysaccharides on adipogenic potential and premature senescence of adipocyte progenitors
- Developments in our understanding of the effects of growth hormone on white adipose tissue from mice: implications to the clinic
- Cellular senescence in aging and age-related disease: from mechanisms to therapy
- Deleted in B reast C ancer 1 regulates cellular senescence during obesity
- Growth differentiation factor 6 derived from mesenchymal stem/stromal cells reduces age-related functional deterioration in multiple tissues
- Mitochondrial dysfunction induces senescence with a distinct secretory phenotype
- Impact of growth hormone on regulation of adipose tissue
- Senescence-associated secretory phenotype (SASP) involvement in the development of cancer, aging, and age related diseases
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- Curcumin, inflammation, ageing and age-related diseases
- Inflammation, ageing and chronic disease
- Geroscience: linking aging to chronic disease
- Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)
- Mitochondrial dysfunction meets senescence
- Finding Shangri-La: limiting the impact of senescence on aging
- Inflamm-ageing
- Characterization of senescence of culture-expanded human adipose-derived mesenchymal stem cells
- An experiment to determine the active therapeutic moiety of sulphasalazine
- Aging of the human innate immune system in HIV infection
- Metabolic syndrome is a real disease and premalignant state induced by oncogenic stresses to block malignant transformation
- Mechanisms and metabolic implications of regional differences among fat depots
- The role of inflammation in age-related disease
- “Inflammaging” as a druggable target: a senescence-associated secretory phenotype—centered view of type 2 diabetes
- Antagonizing Effects of Aspartic Acid against Ultraviolet A-Induced Downregulation of the Stemness of Human adipose tissue-Derived Mesenchymal Stem …
- Cellular senescence: from physiology to pathology
- RETRACTED: Chronic Inflammation: Accelerator of Biological Aging
- Senescence associated macrophages and “macroph-aging”: are they pieces of the same puzzle?
- Cellular senescence and the biology of aging, disease, and frailty
- Targeting senescent cells enhances adipogenesis and metabolic function in old age
- Urinary Iodine Concentrations in Mothers and their Term Newborns
- Aging and osteoarthritis
- Obesity-associated mechanisms of hepatocarcinogenesis
- P12 Pathological vascular smooth muscle cells remodelling in murine models of abdominal aortic aneurysm
- The aging adipose organ: lipid redistribution, inflammation, and cellular senescence
- Ginsenoside Rd attenuates the inflammatory response via modulating p38 and JNK signaling pathways in rats with TNBS-induced relapsing colitis
- Impact of cellular senescence signature on ageing research
- Metabolic and microenvironment changes in the mammary of calorie restricted, normal weight, and obese mice throughout the lifespan
- Senescent cells: a novel therapeutic target for aging and age‐related diseases
- … and Metabolic Dysfunction during Aging and Senescence: Effect of lipopolysaccharides on adipogenic potential and premature senescence of adipocyte …
- Crossing Boundaries to Propel Tissue Engineering into the Clinic
- Mitochondrial damage induces senescence with a twisted arm
- Therapeutic effect and mechanism of proanthocyanidins from grape seeds in rats with TNBS-induced ulcerative colitis
- Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases
- Pathogenesis of hepatocellular carcinoma development in non-alcoholic fatty liver disease
- ÔØ Å ÒÙ× Ö ÔØ
- Aging of the immune system: focus on inflammation and vaccination
- Molecular mechanisms of ageing and related diseases
- Senescent cells: SASPected drivers of age-related pathologies
- Control of p53 and NF-κB signaling by WIP1 and MIF: role in cellular senescence and organismal aging
- p21 both attenuates and drives senescence and aging in BubR1 progeroid mice
- Stop feeding cancer: pro-inflammatory role of visceral adiposity in liver cancer
- Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
- Metabolic control of longevity
- Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells
- Microbiome–Obesity–Liver Cancer Interaction: Senescence of Hepatic Stellate Cells and Bile Acids Play New Roles
- Ameliorative effects of 3, 4-oxo-isopropylidene-shikimic acid on experimental colitis and their mechanisms in rats
- Hepatocellular carcinoma and lifestyles
- Inflammation and cellular senescence: potential contribution to chronic diseases and disabilities with aging
- Toll like receptor signaling in “inflammaging”: microRNA as new players
- Depleting senescent cells to combat aging
- www. aging-us. com AGING 2016, Vol. 8, Advance
- High-throughput screening reveals enzyme and GPCR targets as putative binding sites for d-deprenyl
- Adipocytes and neutrophils give a helping hand to pancreatic cancers
- Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice
- Anti-inflammatory effects of Pulvis Fellis Suis extract in mice with ulcerative colitis
- Ageing and the pathogenesis of osteoarthritis
- Aging of mice is associated with p16 (Ink4a)-and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells
- Cellular senescence in aging and osteoarthritis: implications for cartilage repair
- Oxidative stress and the ageing endocrine system
- Clinical strategies and animal models for developing senolytic agents
- Liver cancer: connections with obesity, fatty liver, and cirrhosis
- Of flies, mice, and men: evolutionarily conserved tissue damage responses and aging
- Age-dependent dysregulation of innate immunity
- Endothelial progenitor cells: from senescence to rejuvenation
- Aging: a common driver of chronic diseases and a target for novel interventions
- Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells’ homeostasis
- Extracellular microRNAs and endothelial hyperglycaemic memory: a therapeutic opportunity?
- The role of oxidative stress and inflammation in cardiovascular aging
- Cell autonomous and non-autonomous effects of senescent cells in the skin
- A case of rheumatoid arthritis exhibiting accelerating rheumatoid pleurisy during low-dose weekly methotrexate therapy
- Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer
- The role of senescent cells in ageing
- Sowing the seeds of cancer: telomeres and age-associated tumorigenesis
- Tim-3: an emerging target in the cancer immunotherapy landscape
- Effect of traditional Chinese medicinal enemas on ulcerative colitis of rats
- Diabetes and cancer, common threads and missing links
- Hepatocellular carcinoma in nonalcoholic fatty liver: role of environmental and genetic factors
- Translational research in immune senescence: assessing the relevance of current models
- Elimination of p19ARF-expressing cells enhances pulmonary function in mice
- The effects of aging on the development of osteoarthritis
- Cellular senescence impact on immune cell fate and function
- Effects of proanthocyanidins from grape seed on treatment of recurrent ulcerative colitis in rats
- Proanthocyanidins from grape seeds modulate the NF-κB signal transduction pathways in rats with TNBS-induced ulcerative colitis
- Morphological, molecular and functional differences of adult bone marrow-and adipose-derived stem cells isolated from rats of different ages
- The role of insulin resistance in nonalcoholic steatohepatitis and liver disease development–a potential therapeutic target?
- Nonalcoholic fatty liver disease: pathogenesis and disease spectrum
- The possible mechanisms of Picrasma quassiodes (D. Don) Benn. in the treatment of colitis induced by 2, 4, 6-trinitrobenzene sulfonic acid in mice
- Aldosterone induces p21‐regulated apoptosis via increased synthesis and secretion of tumour necrosis factor‐α in human proximal tubular cells
- Senescence as a general cellular response to stress: a mini-review
- Obesity and liver cancer
- Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model
- Reversing multiple age-related pathologies by controlling the senescence-associated secretory phenotype of stem cells
- Histone macroH2A1. 2 promotes metabolic health and leanness by inhibiting adipogenesis
- Pivotal role of Sirt6 in the crosstalk among ageing, metabolic syndrome and osteoarthritis
- Proanthocyanidins from grape seeds modulates the nuclear factor-kappa B signal transduction pathways in rats with TNBS-induced recurrent ulcerative colitis
- Maternal obesity programs senescence signaling and glucose metabolism in osteo-progenitors from rat and human
- Immunosurveillance of senescent cells: the bright side of the senescence program
- Obesity and the gut microbiome: pathophysiological aspects
- Ageing induced vascular smooth muscle cell senescence in atherosclerosis
- Cancer and inflammation: an old intuition with rapidly evolving new concepts
- Obesity and cancer pathogenesis
- Metabolic consequences of HIV: pathogenic insights
- Noncoding RNA control of cellular senescence
- Protective effects of 3, 4-oxo-isopropylidene-shikimic acid on experimental colitis induced by trinitrobenzenesulfonic acid in rats
- Inflammaging decreases adaptive and innate immune responses in mice and humans
- Senescence and the pro-tumorigenic stroma
- Siegesbeckia pubescens ameliorates experimental ulcerative colitis in rats by modulating PPARγ.
- Therapeutic effect of ginsenoside Rd in rats with TNBS-induced recurrent ulcerative colitis
- Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors
- Serum n3 polyunsaturated fatty acids are depleted in Crohn’s disease
- The cell secretome, a mediator of cell-to-cell communication
- Targeting senescent cells: possible implications for delaying skin aging: a mini-review
- DNA damage and innate immunity: links and trade-offs
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
- Protective effect of taurohyodeoxycholic acid from Pulvis Fellis Suis on trinitrobenzene sulfonic acid induced ulcerative colitis in mice
- Chronic inflammation, immune escape, and oncogenesis in the liver: a unique neighborhood for novel intersections
- Mesenchymal stem cells in regenerative medicine: focus on articular cartilage and intervertebral disc regeneration
- Interventions to slow aging in humans: are we ready?
- Anti-inflammatory activity and mechanisms of a lipid extract from hard-shelled mussel (Mytilus coruscus) in mice with dextran sulphate sodium-induced colitis
- DNA damage response and autophagy: a meaningful partnership
- NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies
- mTOR signaling from cellular senescence to organismal aging
- Erdheim–Chester disease: from palliative care to targeted treatment
- Gerosuppressant metformin: less is more
- Chemoprevention of obesity-related liver carcinogenesis by using pharmaceutical and nutraceutical agents
- Workshop report Key data from the 11th International Workshop on Adverse Drug Reactions and Co-Morbidities in HIV
- Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy
- Immune aging, dysmetabolism, and inflammation in neurological diseases
- Anti-inflammatory effects of Huangqin tang extract in mice on ulcerative colitis
- Conditioned media from human umbilical cord blood-derived mesenchymal stem cells inhibits melanogenesis by promoting proteasomal degradation of MITF
- Speeding up the clock: The past, present and future of progeria
- Mathematical integration of protein metabolism in growing lambs
- Short telomeres in key tissues initiate local and systemic aging in zebrafish
- Modelling age-related metabolic disorders in the mouse
- Disease drivers of aging
- Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their anti-tumor activity
- Diabetes and aging
- Exercise attenuates the major hallmarks of aging
- Long noncoding RNAs in diseases of aging
- Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation
- From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes
- Persistent DNA damage‐induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells
- Halofuginone reduces the inflammatory responses of DSS-induced colitis through metabolic reprogramming
- Obesity and cancer
- Senescence in human mesenchymal stem cells: functional changes and implications in stem cell-based therapy
- Bile acids and the gut microbiome
- Aging, clonality, and rejuvenation of hematopoietic stem cells
- Dysregulated inflammation as a risk factor for pneumonia in the elderly
- Ageing and the telomere connection: An intimate relationship with inflammation
- The study of skeletal aging is coming of age: A forum on aging and skeletal health
- Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of INS-1 …
- Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression
- Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
- SYSTEMIC DNA DAMAGE RESPONSE AND METABOLIC SYNDROME
- Secreted microvesicular miR‐31 inhibits osteogenic differentiation of mesenchymal stem cells
- Are there roles for brain cell senescence in aging and neurodegenerative disorders?
- Effect of Manuka honey and sulfasalazine in combination to promote antioxidant defense system in experimentally induced ulcerative colitis model in rats
- Effect of hyperglycemia on hepatocellular carcinoma development in diabetes
- NF-κB in aging and disease
- Toward the comprehensive understanding of the gut ecosystem via metabolomics-based integrated omics approach
- Interleukin‐8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor‐α and interleukin‐1β
- Energetic interventions for healthspan and resiliency with aging
- Secretome of human fetal mesenchymal stem cell ameliorates replicative senescence
- Caloric restriction and aging stem cells: the stick and the carrot?
- Exercise enhances wound healing and prevents cancer progression during aging by targeting macrophage polarity
- The promise of slow down ageing may come from curcumin
- Effects of mimic of manganese superoxide dismutase on 2, 4, 6-trinitrobenzene sulfonic acid-induced colitis in rats
- Genome-wide chromatin state transitions associated with developmental and environmental cues
- Oxidative stress, cellular senescence and ageing
- 7 Immune Senescence
- What Is Homeostasis?
- Atypical pyoderma gangrenosum with leukemia
- INVESTIGATING MOLECULAR PATHWAYS OF ROS-INDUCED PRO-INFLAMMATORY SENESCENCE IN PREADIPOCYTES
- Vascular wall-resident multipotent stem cells of mesenchymal nature within the process of vascular remodeling: cellular basis, clinical relevance, and …
- Recombinant HSP70 and mild heat shock stimulate growth of aged mesenchymal stem cells
- Senescence in chronic obstructive pulmonary disease
- Fibrogenesis and carcinogenesis in nonalcoholic steatohepatitis (NASH): involvement of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase …
- Non-alcoholic steatohepatitis and hepatocellular carcinoma: implications for lycopene intervention
- Telomeres and age-related disease: how telomere biology informs clinical paradigms
- Characterization of the human salivary proteome by capillary isoelectric focusing/nanoreversed-phase liquid chromatography coupled with ESI-tandem MS
- Macromolecular degradation systems and cardiovascular aging
- Acute phase serum amyloid A induces proinflammatory cytokines and mineralization via toll-like receptor 4 in mesenchymal stem cells
- Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
- Understanding The Regulation Of Adipogenesis And Adipocyte Metabolism In Obesity
- Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture
- The senescence arrest program and the cell cycle
- The posttranslational processing of prelamin A and disease
- Caveolae and signalling in cancer
- Therapy with multipotent mesenchymal stromal cells protects lungs from radiation-induced injury and reduces the risk of lung metastasis
- Frailty and sarcopenia as the basis for the phenotypic manifestation of chronic diseases in older adults
- From experimental design to functional gene networks: DNA microarray contribution to skin ageing research
- Senescence-associated MCP-1 secretion is dependent on a decline in BMI1 in human mesenchymal stromal cells
- Tumour biology of obesity-related cancers: understanding the molecular concept for better diagnosis and treatment
- Protective effect of sanguinarine against acetic acid-induced ulcerative colitis in mice
- Living Large: What Mouse Models Reveal about Growth Hormone and Obesity
- Signaling networks determining life span
- Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity
- The second international conference “genetics of aging and longevity”
- Amniotic epithelial cells: a new tool to combat aging and age-related diseases?
- Mesenchymal stem cells in wound repair, tissue homeostasis, and aging
- The role and regulation of the nuclear factor kappa B signalling pathway in human labour
- Physiological regulation of the heat shock response by glutamine: implications for chronic low-grade inflammatory diseases in age-related conditions
- At the stem of youth and health
- New Insights into the Management and Therapeutics of Type 2 Diabetes
- Epigallocatechin-3-gallate ameliorates rats colitis induced by acetic acid
- Cellular and molecular biology of aging endothelial cells
- The nuclear lamina in health and disease
- The Biology of Aging: Role in Cancer, Metabolic Dysfunction, and Health Disparities
- Cellular and molecular basis of the imbalance between vascular damage and repair in ageing and age-related diseases: as biomarkers and targets for new …
- Interrater reliability of a clinical scale to assess knee joint effusion
- Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence?
- Cell cycle arrest and the evolution of chronic kidney disease from acute kidney injury
- Biomarkers and Inflammatory Network in Aging: Targets for Therapies
- Implications of multipotent mesenchymal stromal cell aging
- Connecting the dots: from DNA damage and repair to aging
- Metformin‐mediated increase in DICER1 regulates microRNA expression and cellular senescence
- MicroRNA-34a induces endothelial progenitor cell senescence and impedes its angiogenesis via suppressing silent information regulator 1
- Identification of senescent cells in the bone microenvironment
- Identification of microRNAs dysregulated in cellular senescence driven by endogenous genotoxic stress
- Melatonin and the theories of aging: a critical appraisal of melatonin’s role in antiaging mechanisms
- Increasing longevity through caloric restriction or rapamycin feeding in mammals: common mechanisms for common outcomes?
- Extracellular microRNAs and endothelial hyperglycemic memory: a therapeutic opportunity?
- Skin mirrors human aging
- miR‐335 correlates with senescence/aging in human mesenchymal stem cells and inhibits their therapeutic actions through inhibition of AP‐1 activity
- Effect of different doses of Manuka honey in experimentally induced inflammatory bowel disease in rats
- Illuminating inflammasome activity in vivo
- Metabolic exchanges within tumor microenvironment
- Inflammation and atherosclerosis in rheumatoid arthritis
- From cellular senescence to age-associated diseases: the miRNA connection
- Melatonin reduces endoplasmic reticulum stress and autophagy in liver of leptin‐deficient mice
- Modulation of Membrane Transport Systems
- The role of chromatin reorganization in the process of cellular senescence
- Pleiotropic effects of tocotrienols and quercetin on cellular senescence: introducing the perspective of senolytic effects of phytochemicals
- Role of DNA damage in cardiovascular disease
- The telomere syndromes
- Somatic stem cell aging and malignant transformation–impact on therapeutic application
- Organelle Stress and mTOR in Aging-Associated Inflammation
- ACC 284
- Regulatory roles of miRNAs in aging
- Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells
- Mechanisms of metastatic tumor dormancy
- Liposarcoma
- Liposarcomas-proliferation, senescence and the role of DDIT3
- Senescence bypass in mesenchymal stem cells: a potential pathogenesis and implications of pro-senescence therapy in sarcomas
- Mechanisms of resveratrol-induced inhibition of clonal expansion and terminal adipogenic differentiation in 3T3-L1 preadipocytes
- Progressive loss of SIRT1 with cell cycle withdrawal
- Targeting Senescent Cells to Improve Human Health
- Defining mesenchymal stromal cells responsiveness to IFNγ as a surrogate measure of suppressive potency
- The germline/soma dichotomy: implications for aging and degenerative disease
- Identifying of the causative genes in spontaneous mutant mouse strains by forward-reverse genetics
- Phenylbutyric Acid: simple structure-multiple effects
- The role of immunosenescence in the development of age-related diseases
- Melatonin reverses H2O2‐induced premature senescence in mesenchymal stem cells via the SIRT1‐dependent pathway
- Recent advances in mouse models of obesity-and nonalcoholic steatohepatitis-associated hepatocarcinogenesis
- Cellular senescence and vascular disease: novel routes to better understanding and therapy
- Telomeres, NAFLD and chronic liver disease
- The emergence of geromirs: A group of micrornas implicated in aging
- The Role of Stem Cell Genomic Instability in Aging
- Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic …
- Regulation of senescence by microRNA biogenesis factors
- Host resistance and immune aging
- Coming of age: molecular drivers of aging and therapeutic opportunities
- ISSN 0975-413X CODEN (USA): PCHHAX
- Finding Ponce de Leon’s Pill: challenges in screening for anti-aging molecules
- Thymic involution perturbs negative selection leading to autoreactive T cells that induce chronic inflammation
- An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer
- Growth hormone is a cellular senescence target in pituitary and nonpituitary cells
- MicroRNAs linking inflamm-aging, cellular senescence and cancer
- Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial …
- Medial arterial calcification: an overlooked player in peripheral arterial disease
- Lessons from Hepatocyte-Specific Cyp51 Knockout Mice: Impaired Cholesterol Synthesis Leads to Oval Cell-Driven Liver Injury
- Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy
- Inflammasomes: guardians of cytosolic sanctity
- As we age: Does slippage of quality control in the immune system lead to collateral damage?
- Anti-aging pharmacology: promises and pitfalls
- Neovascularization capacity of mesenchymal stromal cells from critical limb ischemia patients is equivalent to healthy controls
- Effect of hyperglycemia on hepatocellular carcinoma development in diabetes
- Expression of HOXD9 in fibroblast-like synoviocytes from rheumatoid arthritis patients
- The Disrupted Steady-State: Tipping the Balance in Favour of Cancer
- The Way Forward: Translation
- Intervention of aging and its effects on cellular health
- DNA damage response and immune defense: links and mechanisms
- Towards an evidence-based model of aging
- iPSCs as a major opportunity to understand and cure age-related diseases
- The biology of aging: 1985–2010 and beyond
- DNA damage: from chronic inflammation to age-related deterioration
- The emerging role of Notch pathway in ageing: focus on the related mechanisms in age-related diseases
- SPEAKER ABSTRACTS
- miR-29c-3p promotes senescence of human mesenchymal stem cells by targeting CNOT6 through p53–p21 and p16–pRB pathways
- Osteopontin, a key mediator expressed by senescent pulmonary vascular cells in pulmonary hypertension
- NF-κB signaling as a driver of ageing
- The Cellular Senescence Program
- Age-related changes in blood-brain barrier integrity in C57BL/6J mice
- Ultrastructural analysis of changes in neurons of the mouse internal anal sphincter during ageing
- Age-related changes to lumbosacral spinal cord motoneurons that modulate bladder and bowel functions in male C57BL/6 mice
- The metabolic regulation of cellular ageing
- The inflammatory network: bridging senescent stroma and epithelial tumorigenesis
- Cellular senescence and inflammation in aging and age-related disease
- Influence of aging on the quantity and quality of human cardiac stem cells
- Prospects and challenges for the use of stem cell technologies to develop novel therapies for Parkinson disease
- Hypoxia-inducible histone lysine demethylases: impact on the aging process and age-related diseases
- Autophagy and cancer metabolism
- Assessing cell and organ senescence biomarkers
- Sphingolipids in inflammation: pathological implications and potential therapeutic targets
- ÔØ Å ÒÙ× Ö ÔØ
- Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer
- Cellular senescence in cardiovascular diseases: potential age-related mechanisms and implications for treatment
- Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells
- Pathogenesis of osteoarthritis
- Better living through chemistry: caloric restriction (CR) and CR mimetics alter genome function to promote increased health and lifespan
- Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence
- Intestinal anti-inflammatory effect of the rhizome extracts of Menispermum dauricum DC. on trinitrobenzene sulfonic acid induced ulcerative colitis in mice
- Biosprays: From the biomedical to the clinical sciences
- Influence of age and physical fitness on miRna-21, TGF-ß and its receptors in leukocytes of healthy women.
- Caspase inhibition switches doxorubicin-induced apoptosis to senescence
- MicroRNAs as mediators of the ageing process
- Modelling ageing and age-related disease
- PROTECTIVE EFFECT OF RICE BRAN WATER EXTRACT ON PANCREAS OF RATS FED A HIGH-FAT DIET
- New objective findings after whiplash injuries: high blood flow in painful cervical soft tissue: an ultrasound pilot study
- Genome integrity in aging: human syndromes, mouse models, and therapeutic options
- Conditioned medium derived from rat amniotic epithelial cells confers protection against inflammation, cancer, and senescence
- Endothelial cell senescence and thrombosis: ageing clots
- A Fungal Glycosphingolipid Directly Activates Natural Killer T Cells and Rapidly Induces Airways Disease
- NAFLD and hepatocellular Carcinoma: how big a problem is this really?
- Mast cells and histamine are triggering the NF-κB-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammation
- Oral submucous fibrosis: Review on mechanisms of pathogenesis and malignant transformation
- Extracellular vesicles in lung microenvironment and pathogenesis
- Vascular endothelial senescence: from mechanisms to pathophysiology
- Autoimmune atherosclerosis in 3D: how it develops, how to diagnose and what to do
- Physiological roles of the DNA demethylation-associated proteins Gadd45a and Ing1
- Stress-induced premature senescence of endothelial and endothelial progenitor cells
- Regulation of Senescence by microRNAs
- Muscle stem cell aging: regulation and rejuvenation
- kk journal of experimental biology.
- 2.20 Behcet’s disease and miscellaneous rheumatic conditions
- Inflammatory bowel disease part I: ulcerative colitis–pathophysiology and conventional and alternative treatment options
- The Buck Institute: An inside look
- Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells
- Orphan technology: Unfunded early-stage bioscience is dropped off at the firehouse
- Computational approaches for the transcriptomics, proteomics and epigenetic analysis in adult stem cells
- The secret lives of stem cells: Unraveling the molecular basis of stem cell aging
- Positive and negative effects of cellular senescence during female reproductive aging and pregnancy
- Global profiling and relative quantifiction of histones, histone PTMs and histone-modifying enzymes in mesenchymal stem cells using LC-MS/MS and a novel …
- The 10th World Congress on Inflammation
- Ms. No.: METHODS-D-15-00125 R1–Revised Version
- Are aging biomarkers clinically relevant in oncogeriatrics?
- Apocrine secretion: new insights into an old phenomenon
- Molecular links between cellular senescence, longevity and age-related diseases–a systems biology perspective
- Practical Laboratory Medicine
- Stop Aging Disease! ICAD 2014.
- PROGRESS REPORT ON THE ROLE OF MITOCHONDRIAL ISOCITRATE DEHYDROGENASE 2 IN AGE-RELATED HEARING LOSS IN MICE
- Impact of physical activity on immune function and inflammation in the elderly
- Four faces of cellular senescence
- Interventions to slow aging in humans: Are we ready?
- Determination of serum visfatin level in patients with Behcet disease, comparing with normal population
- Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration
- DNA damage: a main determinant of vascular aging
- The Role of Estrogen Deficiency in Skin Aging and Wound Healing
- Comparative analysis of gene expression data reveals novel targets of senescence-associated microRNAs
- Accelerated telomere shortening in acromegaly; IGF-I induces telomere shortening and cellular senescence
- Salvianolic acid B restored impaired barrier function via downregulation of MLCK by microRNA-1 in rat colitis model
- IL-6 and related cytokines as the critical lynchpins between inflammation and cancer
- Anti-stress gene response in cell and tissue ageing: role of transcription factor NF-E2-related factor-2 and effect of dietary activators
- Protective Effect of Paronychia argentea L. on Acetic Acid Induced Ulcerative Colitis in Mice by Regulating Antioxidant Parameters and Inflammatory Markers
- 7th Joint Meeting of the European Tissue Repair Society (ETRS) with the Wound Healing Society
- Human Amniotic Fluid Mesenchymal Stromal cells (AF-MSCs) are Less Prone to in vitro Senescence Process Compared with Bone Marrow MSCs
- The central role of muscle stem cells in regenerative failure with aging
- Modulation of ageing characteristics with an anti-ageing compound
- Insulin pathway and its correlation with ageing and longevity
- Glucocorticoids suppress selected components of the senescence‐associated secretory phenotype
- Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy
- Stem cells and cancer stem cells
- Nutritional Modulators of Cellular Senescence In Vitro
- Non‐cell autonomous or secretory tumor suppression
- The Aging Superorganism
- Systemic problems: a perspective on stem cell aging and rejuvenation
- Modulators of cellular senescence: mechanisms, promises, and challenges from in vitro studies with dietary bioactive compounds
- Pharmacotherapeutics ECG of the Month
- Molecular Mechanisms of Lycopene Actions on Liver Disease Outcomes
- Pathophysiological fundamentals of diabetic cardiomyopathy
- The gut microbial endocrine organ: bacterially derived signals driving cardiometabolic diseases
- The role of miRNAs in common inflammatory arthropathies: osteoarthritis and gouty arthritis
- Similarities in gene expression profiles during in vitro aging of primary human embryonic lung and foreskin fibroblasts
- Rescuing the regenerative capacity of human mesenchymal stem cells from the elderly
- Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
- Nuclear lamina defects cause ATM-dependent NF
- Interventions for age-related diseases: Shifting the paradigm
- An Arf-Egr-C
- Biomolecular bases of the senescence process and cancer. A new approach to oncological treatment linked to ageing
- Aging, Immunosenescence, and Cancer
- A causal role of ATM-and NEMO-dependent NF-κB activation in DNA damage-induced senescence and aging
- Effect of bisphenol A on stress-induced premature senescence
- Progerin Expression Disrupts Critical Adult Stem Cell Functions that Mediate Tissue Repair Primarily through a Mechanism that Permanently Farnesylates Lamin A
- Systemic DNA damage responses in aging and diseases
- Osteoarthritis in the Elderly
- MDM2 levels modulate the cellular senescence response to CDK4 inhibition
- Functional-structural plant modeling
- Placental origins of chronic disease
- Inflammatory dysregulation and cancer: From molecular mechanisms to therapeutic opportunities
- The Role of Integrated Omics in Elucidating the Gut Microbiota Health Potentials
- Allogeneic mesenchymal stem cells transplantation in patients with refractory RA
- Stress-Induced Senescence: Molecular Pathways
- Neovascularization capacity of mesenchymal stromal cells from critical limb ischemia patients is equivalent to healthy controls
- Twist proteins as oxidative and hypoxic stress regulators
- The gut microbiota and the liver: implications for clinical practice
- The Epigenome and Aging
- Protein expression analysis of rat testes induced testicular toxicity with several reproductive toxicants
- Glenn Workshop on the Biology of Aging and AFAR Grantee Conference| JOINT MEETING
- The hallmarks of fibroblast ageing
- Signaling Networks Controlling Cellular Senescence
- Evidences of Early Senescence in Multiple Myeloma Bone Marrow
- Systemic administration of WY-14643, a selective synthetic agonist of peroxisome proliferator activator receptor-alpha, alters spinal neuronal firing in a rodent model of …
- Development of a mouse model for Hutchinson-Gilford progeria syndrome reveal defects in adult stem cell maintenance
- A potential role for miR-31 in osteoblastic transition of vascular smooth muscle cells and cortisol-induced osteoporosis
- Senescent mesenchymal stem cells promote colorectal cancer cells growth via galectin-3 expression
- BLT2 Protects Skin from the Damage Caused by Type 2 Diabetes Hyperglycemia by Increasing NO Production Through the nNOS Expression
- Molecular mechanisms of aging in MTDNA mutator mice
- Reversing stem cell aging: Implications for vascular regeneration
- Targeting the tumor stroma as a novel therapeutic approach for prostate cancer
- The Role of Macrophage Migration Inhibitory Factor in Osteoarthritis
- Evidence supporting the utility of blood cell respiratory capacity as a systemic marker of mitochondrial health and biological age
- Circadian molecular clock in lung pathophysiology
- Stop Aging Disease! ICAD 2014
- Investigating the differential instructive roles of WT1’s isoforms
- Osteoporosis and mechanisms of skeletal aging
- Functional Enrichment Analysis
- mberHappily (n) ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence
- Skin disease in laminopathy-associated premature aging
- Cellular and Molecular Mechanisms of Chronic Inflammation in Aging of Skeletal Muscle
- Oxidative stress-induced JNK activation contributes to proinflammatory phenotype of aging diabetic mesangial cells
- Histone methylation and aging: lessons learned from model systems
- Regulation of Phospholipase Isozymes by Nuclear Factor-κB in Human Gestational Tissues in Vitro
- Fluorescence Spectroscopy
- Psoriasis and inflammatory bowel disease: links and risks
- Prelamin A accelerates vascular calcification via activation of the DNA damage response and senescence-associated secretory phenotype in vascular smooth muscle …
- SIRT1 in endothelial cells as a novel target for the prevention of early vascular aging
- Cellular senescence as the causal nexus of aging
- MicroRNAs Regulate p21Waf1/Cip1 Protein Expression and the DNA Damage Response in Human Embryonic Stem Cells
- Basic Research
- Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective
- Relationships Among Body Mass Index, Nutrition, Internalizing Symptoms, and Ethnic Identity of Cherokee Youth Attending a Private American Indian Secondary …
- The role of the stress response gene Gadd45b in senescence
- False discovery rate (FDR)
- FBA Analysis, Plant-Pathogen Interactions
- Influence of aging on proliferation, pluripotency, immunogenic profiles from bone marrow mesenchymal stem cells
- Macrophage migration inhibitory factor regulates AKT signaling in hypoxic culture to modulate senescence of human mesenchymal stem cells
- Cell and molecular aging
- Loss of HuR leads to senescence-like cytokine induction in rodent fibroblasts by activating NF-κB
- Role of the nuclear envelope in regulation of ageing
- Chemotherapy-and Radiation-Induced Accelerated Senescence: Implications for Treatment Response, Tumor Progression and Cancer Survivorship
- Selenium and Senescence: Centering on Genome Maintenance
- Author statement
- Mechanisms of action of anti-TNF-α antibodies in inflammatory bowel disease
- Immortality: Myth or becoming Reality
- Skin, Mucosa and Menopause
- SUPPLEMENTARY TABLES
- Proteome analysis of formalin-fixed and paraffin-embedded tissue
- Framework Region (FR-IMGT)
- Frequent Pattern Mining
- Founders Effect
- Fisher’s Test
- Frequency
- Frequentist Approach
- Fitness
- Forward-scattered Light (FSC)
- Fluorescent Markers
- Fluorescence Microscopy
- Functional/Signature Network Module for Target Pathway/Gene Discovery
- Forward and Inverse Parameter Estimation for Metabolic Models
- Feature Selection
- Fitness Function
- Feedback Regulation
- Fibroblasts
- Feasibility
- Functional Modules and Complexes
- FunctionalityType
- Flux Balance Analysis
- Fokker–Planck Equation
- Faceted Browsing
- Fluorescence-activated Cell Sorting
- Flow Cytometry
- Frame Language
- Function, biological
- Feed Forward Loop
- Fluorophore
- Fluorescence Microscope
- False Positive Rate
- Fuzzy Logic
- Functional
- Flux Control Coefficient
- Fluorescence
- Functor
- Fourier Transform Infrared Microspectroscopy (FTIR)
- FuGE
- Foundational Model of Anatomy
- Floquet Multiplier
- Function, Distributed
- 9.1 Gut Microbiota
- Ageing and inflammation with focus on end-stage renal diseases: genetic and epigenetic factors
- The pleiotropic effects of HMG-CoA reductase inhibitors in inflammatory arthritis
- Assessing Pain and Inflammation in Arthritis Using Novel Imaging Methods
- The skin as a mirror of the aging process
- Hyperalgesia and allodynia to superficial and deep-tissue mechanical stimulation within and outside of the UVB irradiated area in human skin
- IL-6 secreted from senescent mesenchymal stem cells promotes proliferation and migration of breast cancer cells
- The role of telomere damage in cardiomyocyte ageing
- Gut Microbiota and HCC
- Contributions of telomere biology to human age-related disease
- Adult cardiac stem cells: identity, location and potential
- Human Population Studies of Transcriptome-wide Expression in Age-related Traits
- The Role of Age in Cellular Responses to Microenvironmental Cues as a Breast Cancer Susceptibility Factor
- The effects of chronic and acute toxicological exposures on the expression of the tumor suppressor p16INK4a
- p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism
- P13. 2
- The role of mitochondria in the regulation of gamma rays induced mTOR-dependent senescence
- Regulation of Forkhead BOX O tumor suppressors by Reactive Oxygen Species
- CSI-01–Cell Cycle & Checkpoints
- A novel approach towards finding regulatory microRNAs during phagosomal maturation in infection.
- The Impact of Physical Activity and Antioxidants on Tumor-Skeletal Muscle Crosstalk during Cancer: Deciphering Signaling Pathways Involved in Tumor Growth and …
- Par Proteins in Tumor Formation and Progression
- Identification and characterization of senescence-associated microRNAs in a mouse model of the XFE Progeroid Syndrome
- Immunoregulatory network and cancer-associated genes: molecular links and relevance to aging
- Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast …
- Telomere fragment induced amnion cell senescence: a contributor to parturition?
- Islet Biology/Insulin Secretion
- Telomere dysfunction: Role in arterial aging and hypertension
- Colorectal cancer-promoting activity of the senescent peritoneal mesothelium
- Senescent Carcinoma Associated Fibroblasts Up-regulate Interleukin 8 to Enhance Pancreatic Cancer Progression
- MOVD 2013
- The Role of Prolactin in the Cellular Response to DNA Damaging Agents
- Studies on the Developmental Changes in Parvalbumins of the Catfish, Heteropneustes fossilis (Bloch)
- Forum on aging and skeletal health: summary of the proceedings of an ASBMR workshop
- Analysis of temporal gene expression during Bacillus subtilis spore germination and outgrowth
- Analysis of gene expression during aging of CGNs in culture: implication of SLIT2 and NPY in senescence
- HIF1α regulates Mitochondrial biogenesis and Cellular senescence induced by Gamma Radiation
- Roles of senescence escape and epigenetic modifications in liver cancer
- Autophagy and inflammation in the pathogenesis of idiopathic dilated cardiomyopathy
- Interventions for age-related diseases: shifting the
- Differential expression of cellular senescence markers in the assessment of breast cancer development
- Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammation
- The role of Inhibitor of DNA binding 4 (Id4) in mammary gland development and breast cancer
- The Role of Photodynamic Therapy in Wound Healing and Scarring in Human Skin
- Melatonin maintains mitochondrial membrane potential and attenuates activation of initiator (casp‐9) and effector caspases (casp‐3/casp‐7) and PARP in UVR …
- Pathogenesis of intervertebral disc degeneration
- Thymic involution perturbs negative selection and leads to chronic inflammation
- Elucidating Molecular Changes in CD8+ T cells During Aging
- High-throughput Screening of Age-related Changes in Caenorhabditis elegans
- Causes, consequences, and reversal of immune system aging
- Senescence and apoptosis: dueling or complementary cell fates?
- Frequency of the cancer-resistant phenotype in SR/CR mice and the effect of litter seriation
- Understanding the roles of Non-homologous end joining and p53 after DNA damage
- IGF-binding protein 2–oncogene or tumor suppressor?
- Regulatory Mechanisms of NK-Cell-Mediated Immune Surveillance of Senescent Cells
- Suppression of autophagy during liver regeneration impairs energy charge and hepatocyte senescence in mice
- Mechanisms of tissue injury in autoimmune liver diseases
- Telomere dysfunction and senescence in the ageing lung and age-related lung disease
- HDAC 1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways
- Poster session 3
- The senescent cell induced bystander effect
- The Function and Regulation of Senescent Stromal-Derived Osteopontin
- Effects of chemotherapy and radiotherapy in rectal cancer: significance of different cellular outcomes in tumor behavior
- Polycomb Repressive Complex 1 Coordinates Enhanced Replication and Transcription in Transit Amplifying Chondrogenic Progenitors.
- Molecular Tuning Of Telomerase Activity In Senescent Human T Cells
- Role of squamous cell carcinoma antigen (SCCA) in oncogenic Ras-mediated tumorigenesis
- Increased oxidative and nitrative stress accelerates aging of the retinal vasculature in the diabetic retina
- The role of calcification regulatory proteins in the arterial stiffening of chronic kidney disease stages 3 & 4
- Age-like Phenotype of Microglia During HIV-1 Infection
- Characterisation of the molecular and functional changes
- The biology of aging: implications for diseases of aging and health care in the twenty-first century
- Cytokine and nitric oxide production in inflammatory arthritis
- Anti-Aging Effects of the Transcendental Meditation Program: Analysis of Ojas Level and Global Gene Expression
- Investigating the chondrogenic phenotype in clinically relevant cells: the effect of hTERT expression
- The diet-microbiota-metabolite axis regulates the host physiology
- Role of stromal fibroblasts in prostate carcinoma progression and metabolic reprogramming of cancer cells
- Regulation and inhibition of pro-tumorigenic microenvironments
- Metal-induced oxidative stress in human fibroblasts: A role in cellular ageing
- EVALUATING THE ROLE OF NF-êB SUPPRESSION IN AMELIORATING MAMMALIAN DISEASE: AN EXAMINATION OF INFLAMMATORY BOWEL DISEASE AND …
- Session held on 9 July 2016
- MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a p53 pathway preventing aneuploid cells propagation
- Molecular mechanism underlying the tumor-promoting functions of carcinoma-associated fibroblasts
- Understanding the pathophysiology and challenges of development of medical countermeasures for radiation-induced vascular/endothelial cell injuries: report of a …
- Regulation and Inhibition of Pro-Tumorigenic Microenvironments
- Changes in DNA methylation patterns in mammals with senescence, ageing and energy restriction
- Methamphetamine accelerates cellular senescence and aging through CYP2D-dependent stimulation of ceramide biosynthesis
- Program Committee: Sabine Fleming Markus Boehm Knut Schaekel Martin Metz Thomas Tueting
- Muscle ageing and anabolic response in the context of healthy and chronically HIV infected individuals
- Pathway Profiling Of Replicative And Induced Senescence
- Role of Tumor Suppressor DMP1 in the Initiation and Progression of Breast Cancer
- Revista de
- Endogenous retroelements in cellular senescence and related pathogenic processes: promising drug targets in age-related diseases
- Interactions between mitochondria and inflammatory factors during cellular senescence
- Using drug treatments to control genome behaviour in normal and Hutchinson-Gilford Progeria Syndrome fibroblasts, with and without hTERT immortalisation
- The chronic lymphocytic leukemia clone disrupts the bone marrow microenvironment
- Understanding vascular diseases: lessons from premature aging syndromes
- Epigenetic mechanisms of longevity and aging
- The role of DNA damage and repair in aging through the prism of Koch-like criteria
- Nutritional roles of selenium in cellular and mouse aging
- Anisotropy in the anodic oxidation of silicon in KOH solution
- Tumor Microenvironment
- Investigating the role of DNA polymerase beta in the aging phenotype of Down syndrome
- Diamond Sponsor
- EXTRACELLULAR MATRIX PROTEINS AND EPITHELIAL CELL PLASTICITY IN PROGRESSION OF BREAST AND PROSTATE CANCER
- Noncoding RNA in age-related cardiovascular diseases
- Identification and characterisation of telomere regulatory and signalling pathways after induction of telomere dysfunction
- Activity and controlled delivery of epigallocatechin 3-gallate in the treatment of degenerative disc disease
- State-of-the-Art Lecture
- Whose place is it?: examining the socio-spatial geography of obesity in young adults for an Australian context.
- Tumor Promoting Aspects of Senescence in Cancer Progression
- Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c‐kit+ cardiac progenitor cells by promoting miR‐675
- Higher-Order Unfolding of Peri/Centric Satellite Heterochromatin is an Early and Consistent Event in Cell Senescence: A Dissertation
- Poster session 2
- Hallmarks of progeroid syndromes: Lessons from mice and reprogrammed cells
- Proinflammatory cytokines in breast cancer: mechanisms of action and potential targets for therapeutics
- Nitrous oxide analgesia for bone marrow aspiration and biopsy–A randomized, controlled and patient blinded study
- 15th International Biennial Congress of the METASTASIS RESEARCH SOCIETY
- PLATFORM PRESENTATIONS
- The Genetic Landscapes of Inflammation-Driven Gastrointestinal Tract Cancers
- The senescent microenvironment promotes the emergence of heterogeneous cancer stem-like cells
- Mutual Reinforcement Between Telomere Capping and Canonical Wnt Pathway Activity in the Intestinal Stem Cell Niche
- The role of nitrosative and metabolic stress in vascular cell senescence
- Expression of p16INK4a in peripheral blood T‐cells is a biomarker of human aging
- MMP-2, MMP-9 production was significantly elevated by fibroblast cells isolated from rheumatoid arthritis patient when co-cultured with monocyte (THP-1) with …
- Evaluating the physiological reserves of older patients with cancer: the value of potential biomarkers of aging?
- POSTER PRESENTATIONS-Sunday, December 7
- Array-based transcriptional analysis of Clostridium sporogenes UC9000 during germination, cell outgrowth and vegetative life
- Pancreatic Dysfunction in Shwachman-Diamond Syndrome
- The wound healing, chronic fibrosis, and cancer progression triad
- Senescence suppressors: their practical importance in replicative lifespan extension in stem cells
- Contributions of Activated Hepatic Stellate Cells to Hepatocarcinogenesis
- Principles of Medical Management of Ulcerative Colitis
- Proceedings of the 26th annual meeting Chiba, Japan, October 18–20, 1984
- Roles of the ING1 Epigenetic Regulator in Breast Cancer
- Directions in Post-Traumatic Arthritis
- Metabolic regulation of intestinal stem cell function in Drosophila melanogaster
- Senescent endothelial cells: Potential modulators of immunosenescence and ageing
- Genotype distribution-based inference of collective effects in genome-wide association studies: insights to age-related macular degeneration disease …
- Sustained low-dose treatment with the histone deacetylase inhibitor LBH589 induces terminal differentiation of osteosarcoma cells
- The multiple roles of A-type lamins in cellular aging, cell cycle progression and the DNA damage response.
- Loss of the osteogenic differentiation potential during senescence is limited to bone progenitor cells and is dependent on p53
- Podocyte Injury Causes Chronic Kidney Disease in the Ercc1 Deficient Mouse Model of Accelerated Aging
- Biological ageing, inflammation and nutrition: how might they impact on systemic sclerosis?
- Detection of mesenchymal stem cells senescence by prelamin A accumulation at the nuclear level
- The role of chondrocyte senescence in osteoarthritis
- A senescent cell bystander effect: Senescence‐induced senescence
- Changes in regenerative capacity through lifespan
- Cancer, Senescence, and Aging: Translation from Basic Research to Clinics
- Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells
- Extracellular matrix and liver disease
- Programmed cell senescence during mammalian embryonic development
- Role of MicroRNA-146a in Vascular Inflammation and Atherosclerosis
- The effect of radiation on cellular ageing
- Programmed cell death in aging
- Update on the mechanisms of action of anti‑TNF‑α antibodies and their clinical implications in inflammatory bowel disease
- Clinical Investigation Program RCS-MED-300 (R1)
- Analysis of Temporal Gene Expression
- Postnatal Hdac3 deficiency in chondrocytes alters cortical bone architecture and increases articular cartilage thickness with age
- EMT and oxidative stress: a bidirectional interplay affecting tumor malignancy
- Regulation of 11β-Hydroxysteroid Dehydrogenase Type 1 and 2 in Rheumatoid Arthritis
- Impacts of Aging and Inflammation on Mycobacterium tuberculosis Control
- A review of melatonin as a suitable antioxidant against myocardial ischemia–reperfusion injury and clinical heart diseases
- Long noncoding RNAs (lncRNAs) and the molecular hallmarks of aging
- Integrative analysis of longevity, age-related diseases and aging-associated processes: Construction of the NetAge database
- SNEVPrp19/PSO4 deficiency increases PUVA‐induced senescence in mouse skin
- miR‐17, miR‐19b, miR‐20a, and miR‐106a are down‐regulated in human aging
- Pašatjaunošanās un paātrinātas novecošanās attiecības normālās un vēža šūnās pēc DNS bojājuma
- Circulating microRNAs as novel biomarkers for bone diseases–Complex signatures for multifactorial diseases?
- Aldehyde dehydrogenase activity of breast cancer stem cells is primarily due to isoform ALDH1A3 and its expression is predictive of metastasis
- Time-and Concentration-dependent response of a liver cell line to Benzo (a) pyrene
- Practical alternatives to chronic caloric restriction for optimizing vascular function with ageing
- Manipulation du métabolisme énergétique dans les leucémies aiguës myéloïdes: mitochondrie, apoptose et mécanisme d’action de la metformine
- Insulin-like growth factor binding protein-6 delays replicative senescence of human fibroblasts
- Intervention in Genotoxic Stress–Induced Senescence by Cordycepin Through Activation of eIF2α and Suppression of Sp1
- p62: linking protein homeostasis and the DNA damage response during ageing
- Molecular basis of Osteoarthritis and aspects of cellular senescence in disease
- Etude du facteur de réparation de l’ADN, Xeroderma pigmentosum du groupe C (XPC), dans les cellules souches hématopoïétiques
- HIV-1 Infection, Antiretroviral Therapies, and HIV-Associated Atherosclerosis
- The role of the transcriptional regulation of stromal cells in chronic inflammation
- Cell ageing: a flourishing field for neurodegenerative diseases
- Senescence of bone marrow mesenchymal stromal cells is accompanied by activation of p53/p21 pathway in myelodysplastic syndromes
- Rat retinal transcriptome: effects of aging and AMD-like retinopathy
- Aging of the liver: what this means for patients with HIV
- Pharmacology and biochemistry of salicylates and related drugs
- A report to inform the development of a clinical practice guideline for rehabilitation post total knee arthroplasty in a South African public hospital
- Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging‐related diseases
- Cellular responses to zinc involving the transcription factor ZNF658 and its target genes
- Determining the role of scavenger receptor class B type I as a source of cholesterol for de novo androgen synthesis in castration-resistant prostate cancer
- Antioxidant properties of mesalamine in colitis inhibit phosphoinositide 3-kinase signaling in progenitor cells
- Aging and the Host Response to Implanted Biomaterials
- A role for epigenetics in aging and the age-dependent response to ionizing radiation
- Interleukin 6 signaling regulates promyelocytic leukemia protein gene expression in human normal and cancer cells
- Mechanisms of microRNAs in atherosclerosis
- Mechanisms of Ageing and Development
- Telomeres and telomerase: their mechanisms of action and the effects of altering their functions
- Lifespan‐extending caloric restriction or m TOR inhibition impair adaptive immunity of old mice by distinct mechanisms
- Fourth International Ankle Symposium, July 16–18, 2009, Sydney, Australia
- Telomeres, Aging, and Nutrition
- Perspectives in pain research 2014: neuroinflammation and glial cell activation: the cause of transition from acute to chronic pain?
- On the Role of Prelamin A in the Heart
- Therapeutic effects and the underlying mechanisms of qing-dai powder against experimental colitis in mice
- Role of Gut Microbiome in the Modulation of Environmental Toxicants and Therapeutic Agents
- 43nd Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung eV (ADF)
- furanosidase f
- Stellate cells
- Pressure and cold pain threshold reference values in a large, young adult, pain-free population
- The ENRGISE Pilot Study Protocol
- A Comparative Analysis of Stress Granule Assembly in Replicative and Stress-Induced Premature Senescence
- Mutant lamin A links prophase to a p53 independent senescence program
- Identification and characterization of downstream effector protein (s) regulated by p53 and pRb
- Long-term efficacy of spironolactone on pain, mood, and quality of life in women with fibromyalgia: An observational case series
- Telomere shortening and immune activity in war veterans with posttraumatic stress disorder
- KAROLINSKA INSTITUTET, STOCKHOLM, SWEDEN
- Interplay between the myc oncoprotein, cyclin-dependent kinases and e3 ubiquitin ligases
- Calcitonin gene-related peptide (CGRP) in age-associated vascular inflammation and leukocyte trafficking
- The Contribution of DNA Interstrand Crosslinks to Aging
- ART. IV.–A Statistical Contribution to our knowledge of Abscess, and other Diseases Consequent upon the Lodgment of Foreign Bodies in the Appendix Vermiformis …
- Molecular Mechanisms of Cancer Progression: The Central Role of the Retinoblastoma Family Members
- Determination of Autoantibody IgG Subclass and Partial Sequence using Multi-affinity Purification with Multi-enzymatic Digestion by LC-MS
- Investigating the role of mitochondrial respiratory chain activity and mitochondrial DNA damage in skin ageing
- Prevalence of lumbo-pelvic pain and factors associated with it in cyclists in Johannesburg
- Health Ballistics: Multiple Reference Point Informed Probability Theory
- Translational Science 2014 Meeting Abstracts
- Proteomic profiling following cryopreservation
- Functional interaction between FOXO4 and p53 in response to oncogenic BRAF signaling
- Translational Science 2014 Meeting Abstracts
- Mechanism of Tumorigenesis by Cancer-Associated Mutations of INI1/SMARCB1, a Component of the SWI/SNF Chromatin Remodeling Complex
- Ecology of juvenile salmon in shallow tidal freshwater habitats in the vicinity of the Sandy River delta, lower Columbia River, 2008
- The role of bone morphogenetic protein 4 in the pathogenesis of choroidal neovascularization in age-related macular degeneration
- The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis
- Sarcopenic obesity or obese sarcopenia: a cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the …
- Cellular Senescence Biomarker p16INK4a+ Cell Burden in Thigh Adipose is Associated With Poor Physical Function in Older Women
- Expansion of adipose tissue‐derived stromal cells at “physiologic” hypoxia attenuates replicative senescence
- Age-induced changes in white, brite, and brown adipose depots: a mini-review
- adipose tissue inflammation in aging
- Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time
- Cellular aging contributes to failure of cold-induced beige adipocyte formation in old mice and humans
- Healthy ageing in 2016: Obesity in geroscience—is cellular senescence the culprit?
- Micro-RNAS regulate metabolic syndrome-induced senescence in porcine adipose tissue-derived mesenchymal stem cells through the P16/MAPK pathway
- Therapeutic doses of doxorubicin induce premature senescence of human mesenchymal stem cells derived from menstrual blood, bone marrow and adipose tissue
- Growth hormone’s effect on adipose tissue: quality versus quantity
- Aging, cell senescence, and chronic disease: emerging therapeutic strategies
- Neovascular deterioration, impaired NADPH oxidase and inflammatory cytokine expression in adipose-derived multipotent cells from subjects with metabolic …
- Dietary restriction ameliorates age-related increase in DNA damage, senescence and inflammation in mouse adipose tissuey
- Fisetin is a senotherapeutic that extends health and lifespan
- adipose tissue-derived extracellular fraction characterization: biological and clinical considerations in regenerative medicine
- Fat depot-specific differences of macrophage infiltration and cellular senescence in obese bovine adipose tissues
- Source of chronic inflammation in aging
- Aging impairs beige adipocyte differentiation of mesenchymal stem cells via the reduced expression of Sirtuin 1
- Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice
- Reduction of premature aging markers after gastric bypass surgery in morbidly obese patients
- Age-and tissue-specific expression of senescence biomarkers in mice
- Senolytics improve physical function and increase lifespan in old age
- Silencing of the small GTPase DIRAS3 induces cellular senescence in human white adipose stromal/progenitor cells
- ANGPTL2―A New Causal Player in Accelerating Heart Disease Development in the Aging―
- Melatonin prevents senescence of canine adipose-derived mesenchymal stem cells through activating NRF2 and inhibiting ER stress
- Cellular senescence: a translational perspective
- Rejuvenating senolytics
- Regulation of lipogenesis in human adipose tissue: Effect of metabolic stress, dietary intervention and aging.
- Cellular senescence in osteoarthritis pathology
- Metabolic memory of dietary restriction ameliorates DNA damage and adipocyte size in mouse visceral adipose tissue
- Aging of Brown and Beige/Brite adipose tissue
- Impact of senescence‐associated secretory phenotype and its potential as a therapeutic target for senescence‐associated diseases
- Cellular Senescence: At the Nexus of Mechanisms of Age-and Obesity-Related Metabolic Dysfunction
- The Progressive Low Chronic Inflammation On Oral Tissues In Elderly
- High Circulating Levels of ANGPTL2: Beyond a Clinical Marker of Systemic Inflammation
- Basic research: killing the old: cell senescence in atherosclerosis
- Cellular senescence: implications for metabolic disease
- Melatonin regulates PARP 1 to control the senescence‐associated secretory phenotype (SASP) in human fetal lung fibroblast cells
- Examination of the Inhibitory Protein P21 in Omento Fat as an Indication of Adipocyte Proliferation
- Augmentation of Dermal Wound Healing by adipose tissue-Derived Stromal Cells (ASC)
- Cell-free therapy with the secretome of adipose tissue-derived stem cells in rats’ frozen-thawed ovarian grafts
- The Complexity of adipose tissue
- Targeting cellular senescence prevents age-related bone loss in mice
- Targeting our aging cells to treat metabolic disease
- Different response to hypoxia of adipose-derived multipotent cells from obese subjects with and without metabolic syndrome
- Mitochondria in cell senescence: is mitophagy the weakest link?
- Diabetes and Adipocyte Dysfunction
- Nonalcoholic fatty liver disease promotes hepatocellular carcinoma through direct and indirect effects on hepatocytes
- Short-term sustained hyperglycaemia fosters an archetypal senescence-associated secretory phenotype in endothelial cells and macrophages
- Senescence and aging: Causes, consequences, and therapeutic avenues
- A summary of the Proceedings of the Thirteenth International Symposium on the Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria July 17–22, 2016
- Killing the old: cell senescence in atherosclerosis
- New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463
- Parallels Between Skeletal Muscle and Bone Aging
- Aging, obesity, and inflammatory age-related diseases
- Molecular pathology endpoints useful for aging studies
- Cellular senescence in postmitotic cells: beyond growth arrest
- Senescent cells: an emerging target for diseases of ageing
- Prevention of senescence in vasculature through quiescence
- Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri
- Inflammageing and metaflammation: the yin and yang of type 2 diabetes
- Chronic inflammation and sarcopenia: A regenerative cell therapy perspective
- Ageing: from inflammation to cancer
- Senotherapy: growing old and staying young?
- Down-regulation of guanylate binding protein 1 causes mitochondrial dysfunction and cellular senescence in macrophages
- Cellular senescence: Molecular mechanisms and pathogenicity
- Anti-inflammatory effect of Chang-An-Shuan on TNBS-induced experimental colitis in rats
- Senescent B cells in aging and age-related diseases: their role in the regulation of antibody responses
- The fountain of youth by targeting senescent cells?
- HIV-associated cellular senescence: a contributor to accelerated aging
- Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
- Activated tissue-resident mesenchymal stromal cells regulate natural killer cell immune and tissue-regenerative function
- Immunosenescence induced by plasma from individuals with obesity caused cell signaling dysfunction and inflammation
- Circadian Disruption, Sleep Loss, and Low-Grade Inflammation
- Histone MacroH2A1: a chromatin point of intersection between fasting, senescence and cellular regeneration
- PPARα regulates tumor cell proliferation and senescence via a novel target gene carnitine palmitoyltransferase 1C
- p16 (Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli
- Novel Role of Blackberries in Senescence and Atherosclerosis in ApoE-/-Mice
- The Role of Na/K-ATPase Signaling in Oxidative Stress Related to Aging: Implications in Obesity and Cardiovascular Disease
- Cellular senescence in renal ageing and disease
- Quantitative analysis of cellular senescence in culture and in vivo
- Ketone bodies mimic the life span extending properties of caloric restriction
- Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2‐independent mechanism
- Gut microbiota and mTOR signaling: insight on a new pathophysiological interaction
- Gut microbiota, fatty liver disease, and hepatocellular carcinoma
- Increase in tumor suppressor Arf compensates gene dysregulation in in vitro aged adipocytes
- Inhibiting cellular senescence: a new therapeutic paradigm for age-related osteoporosis
- The Na/K-ATPase oxidant amplification loop regulates aging
- Role of lncRNAs in aging and age‐related diseases
- TNFα-senescence initiates a STAT-dependent positive feedback loop, leading to a sustained interferon signature, DNA damage, and cytokine secretion
- Gut microbiota-mediated inflammation in obesity: a link with gastrointestinal cancer
- The impact of senescence-associated T cells on immunosenescence and age-related disorders
- Study on the therapeutic effects of salicylazosulfapyridine on ulcerative colitis in rats
- Emerging metabolic risk factors in hepatocellular carcinoma and their influence on the liver microenvironment
- Low-grade inflammation in the relationship between sleep disruption, dysfunctional adiposity, and cognitive decline in aging
- Musculoskeletal senescence: a moving target ready to be eliminated
- Inflammatory response in the CNS: friend or foe?
- Inflammation-accelerated senescence and the cardiovascular system: mechanisms and perspectives
- Biphasic modeling of mitochondrial metabolism dysregulation during aging
- Myeloid-derived suppressor cells (MDSC): an important partner in cellular/tissue senescence
- Mitochondrial peptides modulate mitochondrial function during cellular senescence
- Senescence of mesenchymal stem cells
- Sirtuins, a promising target in slowing down the ageing process
- Endothelin receptor type b blocker attenuates severity of osteoarthritis by clearance of senescent cells
- The Rbm38-p63 feedback loop is critical for tumor suppression and longevity
- Identification of senescent cell surface targetable protein DPP4
- Caloric Restriction, Sirtuins, and Ageing
- 5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR
- SCAMP4 enhances the senescent cell secretome
- Age-related changes in glucose metabolism, hyperglycemia, and cardiovascular risk
- Investigating the Role of NRIP1 in Skin Aging: Depletion of NRIP1 Delays Senescence, Reduces Inflammation and Enhances Autophagy in Adipocytes
- The role of cellular senescence in aging through the prism of Koch-like criteria
- Heat-induced extracellular HSP72 release is blunted in elderly diabetic people compared with healthy middle-aged and older adults, but it is partially restored by …
- Drosophila as a Model to Study the Link between Metabolism and Cancer
- Oxidative stress-mediated senescence in mesenchymal progenitor cells causes the loss of their fibro/adipogenic potential and abrogates myoblast fusion
- Immune Senescence and Inflammaging in Neurological Diseases
- Inflammaging and human longevity in the omics era
- Role of sphingolipids in senescence: implication in aging and age-related diseases
- Mitochondrial activity and dynamics changes regarding metabolism in ageing and obesity
- Premature physiologic aging as a paradigm for understanding increased risk of adverse health across the lifespan of survivors of childhood cancer
- The molecular intersection between senescence and major depression in the elderly
- Senescent cells: a new Achilles’ heel to exploit for cancer medicine?
- From cellular senescence to age-associated diseases: miRNAs as tools and targets for healthy ageing
- Attenuation of inflammation and cartilage degradation by sulfasalazine-containing hyaluronic acid on osteoarthritis rat model
- Ripk3 regulates cardiac microvascular reperfusion injury: the role of IP3R-dependent calcium overload, XO-mediated oxidative stress and F-action/filopodia-based …
- The dual role of cellular senescence in developing tumors and their response to cancer therapy
- Identification of new genes associated to senescent and tumorigenic phenotypes in mesenchymal stem cells
- Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing
- Cellular senescence in osteoarthritis and anti-aging strategies
- Downregulation of miR-130b~ 301b cluster is mediated by aberrant promoter methylation and impairs cellular senescence in prostate cancer
- Hydrogen sulfide ameliorates aging-associated changes in the kidney
- The peritoneal “soil” for a cancerous “seed”: a comprehensive review of the pathogenesis of intraperitoneal cancer metastases
- Aging mechanisms and intervention targets
- Inflammaging and ‘Garb-aging’
- NLRP3 inflammasome activation in inflammaging
- Mechanisms and functions of cellular senescence
- The Effects of the Senescent Preadipocyte Secretome on Skeletal Muscle Cells
- Ras signaling in aging and metabolic regulation
- Cellular senescence in brain aging and neurodegenerative diseases: evidence and perspectives
- Anthracycline cardiotoxicity: looking for new therapeutic approaches targeting cell senescence?
- Coenzyme Q10 prevents senescence and dysfunction caused by oxidative stress in vascular endothelial cells
- Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and relation to vascular endothelial function
- Senescent cells and osteoarthritis: a painful connection
- Oncogenic KRAS and the Inflammatory Micro-Environment in Pancreatic Cancer
- Linking cellular stress responses to systemic homeostasis
- Cellular senescence, senescence-associated secretory phenotype, and chronic kidney disease
- With great age comes great metastatic ability: ovarian cancer and the appeal of the aging peritoneal microenvironment
- Lipometabolism and Glycometabolism in Liver Diseases
- A null mutation in SERPINE1 protects against biological aging in humans
- CELLULAR STRESS RESPONSE GENES IN ALZHEIMER’S DISEASE: INSIGHTS FROM GENOME-WIDE ASSOCIATION STUDIES
- Osteoarthritis Biology
- Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis
- Oxidative stress in mesenchymal stem cell senescence: regulation by coding and noncoding RNAs
- Divergent mechanisms of metabolic dysfunction drive fibroblast and T-cell senescence
- Is the secret for a successful aging to keep track of cancer pathways?
- Acute genotoxic stress-induced senescence in human mesenchymal cells drives a unique composition of senescence messaging secretome (SMS)
- HIF1α deletion facilitates adipose stem cells to repair renal fibrosis in diabetic mice
- Deletion of Nrip1 Extends Female Mice Longevity, Increases Autophagy, and Delays Cell Senescence
- Calcium signaling and cellular senescence
- Stress, cell senescence and organismal ageing
- Senescence as a novel mechanism involved in β-adrenergic receptor mediated cardiac hypertrophy
- Activation of sirtuin 1 by catalpol-induced down-regulation of microRNA-132 attenuates endoplasmic reticulum stress in colitis
- Secondary Unconjugated Bile Acids Induce Hepatic Stellate Cell Activation
- MicroRNA regulation of oxidative stress-induced cellular senescence
- Yields and chondrogenic potential of primary synovial mesenchymal stem cells are comparable between rheumatoid arthritis and osteoarthritis patients
- The spectrum of fundamental basic science discoveries contributing to organismal aging
- Seasonal variation in vitamin D in association with age, inflammatory cytokines, anthropometric parameters, and lifestyle factors in older adults
- The imbalance between n-6/n-3 polyunsaturated fatty acids and inflammatory bowel disease: a comprehensive review and future therapeutic perspectives
- Aging, inflammation and the environment
- Rejuvenation of aged hematopoietic stem cells
- Pathogenesis of wound healing disorders in the elderly
- Microvesicles as potential biomarkers for the identification of senescence in human mesenchymal stem cells
- Aging and the immune system: An overview
- The light and shadow of senescence and inflammation in cardiovascular pathology and regenerative medicine
- BBA-Molecular Basis of Disease
- The impact of the Standard American Diet in rats: Effects on behavior, physiology and recovery from inflammatory injury
- The macroH2A1. 1–PARP1 axis at the intersection between stress response and metabolism
- Integrative Cardiovascular Physiology and Pathophysiology: Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and …
- Circulating markers of ageing and allostatic load: A slow train coming
- Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition
- The Role of p16-Positive Senescent Cells in an Age-Related Disease and Aging Itself
- Regulation of normal and leukemic stem cells through cytokine signaling and the microenvironment
- Autophagy and the cell biology of age-related disease
- Using comparative biology to understand how aging affects mitochondrial metabolism
- Maternal obesity impairs skeletal development in adult offspring
- Cellular senescence links aging and diabetes in cardiovascular disease
- Apelin/APJ system: A novel promising target for anti-aging intervention
- The gut–liver axis and the intersection with the microbiome
- Targeting senescent cells in fibrosis: pathology, paradox, and practical considerations
- A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse
- Mesenchymal stem cells secretory responses: senescence messaging secretome and immunomodulation perspective
- Cell cycle and apoptosis regulator 2 at the interface between DNA damage response and cell physiology
- Mechanisms of normal tissue injury from irradiation
- Immunological aspects of age-related diseases
- Happily (n) ever after: aging in the context of oxidative stress, proteostasis loss and cellular senescence
- Senescence in hepatic stellate cells as a mechanism of liver fibrosis reversal: a putative synergy between retinoic acid and PPAR-gamma signalings
- Senescence in health and disease
- Linking a role of lncRNAs (long non-coding RNAs) with insulin resistance, accelerated senescence, and inflammation in patients with type 2 diabetes
- Emerging players at the intersection of chondrocyte loss of maturational arrest, oxidative stress, senescence and low-grade inflammation in osteoarthritis
- Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing
- Immunologic
- Nutrient sensing pathways as therapeutic targets for healthy ageing
- Articular cartilage aging-potential regenerative capacities of cell manipulation and stem cell therapy
- Fibroblast activation and senescence in oral cancer
- MicroRNAs and the metabolic hallmarks of aging
- Genomic profiling and metabolic homeostasis in primary liver cancers
- Mitochondria, oxidative stress and innate immunity
- Human menstrual blood: a renewable and sustainable source of stem cells for regenerative medicine
- Balancing between aging and cancer: molecular genetics meets traditional Chinese medicine
- The mechanism of alopolysaccharide protecting ulceralive colitis
- Glutathione peroxidase 3 delivered by hiPSC-MSCs ameliorated hepatic IR injury via inhibition of hepatic senescence
- Novel strategies for anti-aging drug discovery
- Cellular and molecular mechanisms of asthma and COPD
- The role of kinase modulators in cellular senescence for use in cancer treatment
- Inflammaging
- Sex-specific differences in hypertension and associated cardiovascular disease
- Comparison of several commonly used detection indicators of cell senescence
- Loss of SATB1 Induces a p21 Dependent Cellular Senescence Phenotype in Dopaminergic Neurons
- Effects of bioactive compounds on senescence and components of senescence associated secretory phenotypes in vitro
- The integration of inflammaging in age-related diseases
- Sphingolipids at the Crossroads of NAFLD and Senescence
- Mitochondria, telomeres and cell senescence: implications for lung ageing and disease
- SASP+adipose+tissue+&ots=A6ts81jdo4&sig=3CwomOd726aFBjPd4YNvvOWa1Uk” target=”_blank” rel=”noopener” data-saferedirecturl=”https://www.google.com/url?hl=en&q=https://books.google.com/books?hl%3Den%26lr%3Dlang_en%26id%3D3HCQDwAAQBAJ%26oi%3Dfnd%26pg%3DPA69%26dq%3DSASP%2Badipose%2Btissue%2B%26ots%3DA6ts81jdo4%26sig%3D3CwomOd726aFBjPd4YNvvOWa1Uk&source=gmail&ust=1579364469122000&usg=AFQjCNHEnnkq5JBN1ZAJuDAnchZTXr-Lbw”>Cellular Senescence and their Role in Liver Metabolism in Health and Disease: Overview and Future Directions
- Mechanisms of dysfunction in the aging vasculature and role in age-related disease
- Knockdown of IL-8 Provoked Premature Senescence of Placenta-Derived Mesenchymal Stem Cells
- Treating Age-Related Diseases with Somatic Stem Cells
- Controlling insulin resistance through modulation of interplay between mediators of cellular senescence: A mathematical study
- Mechanisms of renal fibrosis
- Nitric oxide-heat shock protein axis in menopausal hot flushes: neglected metabolic issues of chronic inflammatory diseases associated with deranged heat shock …
- Characterization of brusatol self-microemulsifying drug delivery system and its therapeutic effect against dextran sodium sulfate-induced ulcerative colitis in mice
- Innate immunity and cellular senescence: The good and the bad in the developmental and aged brain
- Stellate cells in tissue repair, inflammation, and cancer
- YAP inhibits the apoptosis and migration of human rectal cancer cells via suppression of JNK-Drp1-mitochondrial fission-HtrA2/Omi pathways
- DHA-enriched fish oil upregulates cyclin-dependent kinase inhibitor 2A (P16INK) expression and downregulates telomerase activity without modulating effects of …
- Antioxidant and anti-senescence effect of metformin on mouse olfactory ensheathing cells (mOECs) may be associated with increased brain-derived neurotrophic …
- Senescent intervertebral disc cells exhibit perturbed matrix homeostasis phenotype
- Procancerogenic activity of senescent cells: A case of the peritoneal mesothelium
- Key proteins and pathways that regulate lifespan
- miRNAs in stem cell aging and age-related disease
- Unhealthy Stem Cells: When Health Conditions Upset Stem Cell Properties
- Cellular senescence and inflammaging in age-related diseases
- Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts
- Isolation and prolonged expansion of oral mesenchymal stem cells under clinical-grade, GMP-compliant conditions differentially affects “stemness” properties
- Extracellular vesicles in the tumor microenvironment: therapeutic resistance, clinical biomarkers, and targeting strategies
- Down-regulation of hepatic MBOAT7 by hyperinsulinemia favors steatosis development
- The Impact of the Mediterranean Diet on Aging, Frailty, and Longevity
- The epigenetics of inflammaging: The contribution of age-related heterochromatin loss and locus-specific remodelling and the modulation by environmental …
- Program & Book of Abstracts: IUBMB Advanced School Nutrition, Metabolism and Aging 2018
- Immune senescence: significance of the stromal microenvironment
- Extracellular vesicles and aging
- Senescence and cell death in chronic liver injury: roles and mechanisms underlying hepatocarcinogenesis
- Energy to Fight Infection
- Senescent, dysfunctional human cardiac progenitor cells (CPCs) accumulate in the aged heart and elimination of senescent cells enhances CPC activation and …
- Cellular senescence, geroscience, cancer and beyond
- Stem Cell Applications in Rejuvenation
- Progeria and accelerated cardiovascular aging
- Camellia Oil (Camellia oleifera Abel.) Modifies the Composition of Gut Microbiota and Alleviates Acetic Acid-Induced Colitis in Rats
- Ionizing radiation-induced cellular senescence promotes tissue fibrosis after radiotherapy. A review
- Major trauma and acceleration of the ageing process
- Inflammatory bowel diseases: Current therapeutic approaches and potential of using stem cells
- PINK1-PARK2-mediated mitophagy in COPD and IPF pathogeneses
- Obesity, Metabolism, and Aging: A Multiscalar Approach
- PPARγ-activation increases intestinal M1 macrophages and mitigates formation of serrated adenomas in mutant KRAS mice
- Current Approaches of Anti-inflammatory-Dependent Antiaging Strategies
- Immunosenescence in neurocritical care
- Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice
- Cellular senescence: a view throughout organismal life
- Effect of Mst1 on endometriosis apoptosis and migration: role of Drp1-related mitochondrial fission and parkin-required mitophagy
- Ceramide synthase 4: a novel metabolic regulator of oncogene-induced senescence
- Regulation and function of p53: A perspective from Drosophila studies
- Relevance of the p53–MDM2 axis to aging
- Administration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice
- Exercise and bone health across the lifespan
- Urothelial senescence in the pathophysiology of diabetic bladder dysfunction-a novel hypothesis
- Gut microbiota’s relationship with liver disease and role in hepatoprotection by dietary natural products and probiotics
- Developmental programming of aging trajectory
- Senescent microvesicles: a novel advance in molecular mechanisms of atherosclerotic calcification
- Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging
- Disruptions in gut microbial-host co-metabolism and the development of metabolic disorders
- In vivo effects of DNA lesions in Nucleotide Excision Repair deficient mice
- Bone Research Society, Annual Meeting 2017 Proceedings
- The clinical potential of senolytic drugs
- Anti-senescence compounds: a potential nutraceutical approach to healthy aging
- Loss of ovarian hormones and accelerated somatic and mental aging
- Inflammation and premature aging in advanced chronic kidney disease
- C. elegans eats its own intestine to make yolk leading to multiple senescent pathologies
- Aging With HIV and Oxidative Stress
- Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine
- DICER1: a key player in rheumatoid arthritis, at the crossroads of cellular stress, innate immunity, and chronic inflammation in aging
- miR-125a induces apoptosis, metabolism disorder and migrationimpairment in pancreatic cancer cells by targeting Mfn2-related mitochondrial fission
- Biology of Aging
- Cellular senescence in tissue repair: every cloud has a silver lining
- Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis
- Automated image analysis detects aging in clinical-grade mesenchymal stromal cell cultures
- Cellular senescence, neurological function, and redox state
- Mesenchymal stem cell therapy protects lungs from radiation-induced endothelial cell loss by restoring superoxide dismutase 1 expression
- Mechanisms of vascular aging
- Environmental and Physiological Cues on the Hypothalamus During Aging
- Reaction time in healthy elderly is associated with chronic low-grade inflammation and advanced glycation end product
- Phospholipase C delta 4 (PLCδ4) is a nuclear protein involved in cell proliferation and senescence in mesenchymal stromal stem cells
- Epigenetics in cardiac fibrosis: emphasis on inflammation and fibroblast activation
- Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells
- PGC-1α protects RPE cells of the aging retina against oxidative stress-induced degeneration through the regulation of senescence and mitochondrial quality control …
- Pro-resolving lipid mediators: Agents of anti-ageing?
- Hyperglycaemia Stress-Induced Renal Injury is Caused by Extensive Mitochondrial Fragmentation, Attenuated MKP1 Signalling, and Activated JNK-CaMKII-Fis1 …
- Energy restriction in renal protection
- Targeting cancer stem cells and their niche: Perspectives for future therapeutic targets and strategies
- Senescence-associated microRNAs
- Cellular senescence and liver disease: Mechanisms and therapeutic strategies
- Gene expression hallmarks of cellular ageing
- Facing up to the global challenges of ageing
- Melatonin and inflammation—Story of a double‐edged blade
- The role of myeloid-derived suppressor cells (MDSC) in the inflammaging process
- Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption
- In vivo and in vitro study on the efficacy of terpinen-4-ol in dextran sulfate sodium-induced mice experimental colitis
- The emerging roles of microRNAs in stem cell aging
- Bone marrow-derived mesenchymal stromal cells promote colorectal cancer cell death under low-dose irradiation
- Umbilical cord–derived mesenchymal stromal cell–conditioned medium exerts in vitro antiaging effects in human fibroblasts
- Tetraploidy in cancer and its possible link to aging
- Senescent cells: a therapeutic target for cardiovascular disease
- Non-Cell autonomous effects of the senescence-associated secretory phenotype in cancer therapy
- The effect of green tea extract compounds on regulation of glucose homoeostasis in insulin-sensitive and breast cancer cells
- Mammalian STE20-Like Kinase 1 Deletion Alleviates Renal Ischaemia-Reperfusion Injury via Modulating Mitophagy and the AMPK-YAP Signalling Pathway
- Immunosenescence: the role of aging in the predisposition to neuro-infectious complications arising from the treatment of multiple sclerosis
- SIPS as a model to study age-related changes in proteolysis and aggregate formation
- Epithelial cell cycle behaviour in the injured kidney
- Immunosenescence and Ageing in HIV
- Long-term persistent organic pollutants exposure induced telomere dysfunction and senescence-associated secretary phenotype
- Aging, Telomere Integrity, and Antioxidant Food
- Advances in tendon mechanobiology
- DICER1: a key player in rheumatoid arthritis, at the crossroads of cellular stress, innate immunity and chronic inflammation in ageing
- G Protein-Coupled Receptor Systems as Crucial Regulators of DNA Damage Response Processes
- NR4A1 contributes to high-fat associated endothelial dysfunction by promoting CaMKII-Parkin-mitophagy pathways
- Age, gender and UV-exposition related effects on gene expression in in vivo aged short term cultivated human dermal fibroblasts
- Role Of COX2 In Cellular Senescence
- Tissue aging: the integration of collective and variant responses of cells to entropic forces over time
- Counterregulatory Effects of Ptx3 on Inflammation and Cellular Aging
- Resveratrol as an Activator or Inhibitor of Enzymes and Proteins
- Induction of a senescence-like phenotype in cultured human fetal microglia during HIV-1 infection
- Vitamin C, aging and Alzheimer’s disease
- Screening and treating prostate cancer in the older patient: decision making across the clinical spectrum
- Mechanisms driving the ageing heart
- Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo
- Biomedical Research in Aging
- Modelling of mitochondrial metabolism in breast cancer
- Age and age-related diseases: role of inflammation triggers and cytokines
- Inducers of senescence, toxic compounds, and Senolytics: the multiple faces of Nrf2-activating phytochemicals in Cancer adjuvant therapy
- Epidermal Growth Factor Therapy Impact on Scar Tissue Resilience of Diabetic Lower Limbs Ulcers-An Enlightening Hypothesis
- The Impact of Membrane Phospholipid Composition and Extracellular Vesicles on the Immunoregulative Properties of Human Mesenchymal Stromal Cells
- Autophagy regulation in preeclampsia: Pros and cons
- The interplay between immunity and aging in Drosophila
- Reversing the immune ageing clock: lifestyle modifications and pharmacological interventions
- Nitric Oxide Regulates H2O2-Induced Senescence via S-Nitrosylation of NF-κB in Endothelial Cells
- Biliary bile acids in hepatobiliary injury–What is the link?
- Cover ImageReport and Abstracts of the 14th Meeting of IIM, the Interuniversity Institute of Myology,-Assisi (Italy), October 12-15, 2017
- Role of the inflammation-autophagy-senescence integrative network in osteoarthritis
- Novel treatment strategies for chronic kidney disease: insights from the animal kingdom
- Aging hallmarks: the benefits of physical exercise
- mTORC inhibitors as broad-spectrum therapeutics for age-related diseases
- Bioactive nutrients and nutrigenomics in age-related diseases
- The nematode Caenorhabditis elegans as a model for aging research
- Sleep health: reciprocal regulation of sleep and innate immunity
- Osteoblast suppression in multiple myeloma bone disease
- Yap regulates gastric cancer survival and migration via SIRT1/Mfn2/mitophagy
- Hypoxia Prevents Mitochondrial Dysfunction and Senescence in Human Cardiac Progenitor Cells
- Senolytika-současný stav
- In vivo and in vitro study of pancreatic islets aging: impact of endothelial senescence and microparticles on islet function
- Mechanisms of Obesity-related Hepatocarcinogensis
- Identification of rare and common genetic variants associated with hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: mechanisms and clinical …
- Nutrient supply affects the mRNA expression profile of the porcine skeletal muscle
- Application of kinase inhibitors for anti-aging intervention
- Telomeres, aging and exercise: guilty by association?
- Long noncoding RNAs and RNA-binding proteins in oxidative stress, cellular senescence, and age-related diseases
- Effects of exercise on inflammatory, oxidative, and neurotrophic biomarkers on cognitively impaired individuals diagnosed with dementia or mild cognitive impairment …
- DNA damage-induced inflammation and nuclear architecture
- Hormonal modulation of ageing skin microstructure and mechanical properties
- The protective effects of Poria cocos-derived polysaccharide CMP33 against IBD in mice and its molecular mechanism
- Prospects of Pharmacological Interventions to Organismal Aging
- Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence
- Investigating senescence in cellular plasticity and tissue regeneration
- DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age
- Targeting mitochondria to counteract age-related cellular dysfunction
- Attenuated Macrophage Infiltration in Glomeruli of Aged Mice Resulting in Ameliorated Kidney Injury in Nephrotoxic Serum Nephritis
- Mechanisms of Action of Drugs for Treating Endothelial Dysfunction in Diabetes Mellitus
- Nutrient supply affects the mRNA expression profile of the porcine skeletal muscle
- Oncogenic roles of the PI3K/AKT/mTOR axis
- Organ reserve, excess metabolic capacity, and aging
- Studies of Novel Factors from Fetal Mesenchymal Stem Cell and Their Applications in Bone and Cartilage Repair
- Secreted α-Klotho maintains cartilage tissue homeostasis by repressing NOS2 and ZIP8-MMP13 catabolic axis
- Extracellular vesicles and their miRNA cargo in ageing and age-associated diseases
- The Pathobiology of Osteoarthritis in Obesity: The Role of Synovial Inflammation, Joint Insulin Resistance, and Dysbiosis of the Gut Microbiome
- Osteobiology of aging
- PTEN enhances nasal epithelial cell resistance to TNFα‑induced inflammatory injury by limiting mitophagy via repression of the TLR4‑JNK‑Bnip3 pathway
- Recent advances in understanding cross-talk between Bile Acids and Gut Microbiota. Open J Proteom Genom 3 (1): 024-034
- Interleukin 1 gene polymorphism and susceptibility to disease
- Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice
- Patent Highlights February–March 2018
- Microbiome and NAFLD: potential influence of aerobic fitness and lifestyle modification
- Advances in Therapeutic Approaches to Extend Healthspan: a perspective from the 2nd Scripps Symposium on the Biology of Aging
- Workshop on Synergies Between Alzheimer’s Research and Clinical Gerontology and Geriatrics: Current Status and Future Directions
- WSB1 overcomes oncogene-induced senescence by targeting ATM for degradation
- A double-blind, randomized trial on the effect of a broad-spectrum dietary supplement on key biomarkers of cellular aging including inflammation, oxidative …
- Innate and adaptive immunity in atherosclerosis
- Functional interaction between melatonin signaling and noncoding RNAs
- Shared molecular and cellular mechanisms of premature ageing and ageing-associated diseases
- Nicotinamide Phosphoribosyltransferase In Smooth Muscle Cells And Aortic Integrity
- Analysis of Aortic Valve Function in the Absence of Endothelial Retinoblastoma Protein
- Oxidative stress and the epigenetics of cell senescence: Insights from progeroid syndromes
- The RNA world of human ageing
- A system for the expression and release of heterologous proteins from the core of Bacillus subtilis spores
- THE CANCER AND BONE SOCIETY (CABS) ANNUAL CONFERENCE
- The versatile role of exosomes in cancer progression: diagnostic and therapeutic implications
- Vascular aging: molecular mechanisms and potential treatments for vascular rejuvenation
- The interplay between immunity and aging in Drosophila
- Submission to the British Geriatrics Society Amulree Prize 2017
- The cancer and bone society (CABS) annual conference Sheraton indianapolis hotel at keystone crossing. Indianapolis, Indiana. May 4-6, 2017
- AAVvector-mediated in vivo reprogramming into pluripotency
- Age-Related Adverse Inflammatory and Metabolic Changes Begin Early in Adulthood
- Toll-like receptor-4 signaling pathway in aorta aging and diseases:“its double nature”
- The Relevance of Induced Pluripotent Stem Cells for the Study of Physiological and Premature Aging
- Turning Round: Optimizing the Anti-Inflammatory Properties of Equine Bone Marrow Derived Mesenchymal Stem Cells for Osteoarthritis Through Three-Dimensional …
- Immunomodulatory properties and senescence-associated secretory phenotypes in human mesenchymal stem cell aging
- Potency of Human Cardiosphere‐Derived Cells from Patients with Ischemic Heart Disease Is Associated with Robust Vascular Supportive Ability
- Stem cells, scaffolds and small molecules for orthopedic tissue regeneration
- Cardiac Effects of Antirheumatic Drugs
- C. Elegans Eats Its Own Intestine to Make Yolk: A Cause of Senescent Polymorbidity
- Senescence Induced by DNA Demethylating Drugs to Treat Solid Tumors
- Autophagy-dependent gut-to-yolk biomass conversion generates visceral polymorbidity in aging C. elegans
- Identification of Molecular Determinants of Cellular Senescence in Cancer and Aging
- as a model for aging research
- Old maids: aging and its impact on microglia function
- Key Age-Imposed Signaling Changes That Are Responsible for the Decline of Stem Cell Function
- The effect of metformin on absolute telomere length
- The role of melatonin, a multitasking molecule, in retarding the processes of ageing
- Chromatin architectural changes during cellular senescence and aging
- Nuclear translocation of argonaute 2 in cytokine-induced senescence
- Inflammation and CMV-associated lymphocyte senescence in chronic HIV infection
- Length-independent telomere damage drives cardiomyocyte senescence
- VRK1 phosphorylates Tip60 acetyltransferase and promotes its accumulation in response to both DNA damage and mitogens
- Induced Cell Turnover: A Novel Therapeutic Modality for In Situ Tissue Regeneration
- Induction de la sénescence endothéliale auriculaire par l’angiotensine II et la thrombine: rôle du stress oxydant et caractérisation du phénotype pro-thrombotique, pro …
- Gestational chronodisruption leads to persistent changes in the rat fetal and adult adrenal clock and function
- Induction of atrial endothelial senescence by angiotensin II and thrombin: role of oxidative stress and characterization of pro-thrombotic, pro-adhesive, proteolytic and …
- Induction of iPS Cell Differentiation Into Connexin26 Positive Cells with Gap Junction Plaques and Characterization of Cochlear Feeder Cell
- AGE-ASSOCIATED LAMIN-B1 REDUCTION IN THE THYMIC EPITHELIAL CELLS AND ITS ROLE IN THYMIC INVOLUTION
- The role of epigenetics in renal ageing
- Cancer and aging-the inflammatory connection
- The role of melanocyte senescence in skin ageing
- Restoring the quantity and quality of elderly human mesenchymal stem cells for autologous cell-based therapies
- Regulation of the Pro-Tumorigenic Senescence-Associated Secretory Phenotype
- LE POTENTIEL HEPATIQUE DES CELLULES SOUCHES MESENCHYMATEUSES RAJEUNNIES ET DES PROGENITEURS ENDODERMIQUES: CONTRIBUTION …
- Different transcriptional profiling between senescent and non-senescent human coronary artery endothelial cells (HCAECs) by omeprazole and lansoprazole …
- Adoptive autophagy activation: a much-needed remedy against chemical induced neurotoxicity/developmental neurotoxicity
- Aging and Antiaging Strategies
- Comparison of mesenchymal stem cells obtained by suspended culture of synovium from patients with rheumatoid arthritis and osteoarthritis
- Antiretroviral Drug Mediated Astrocyte Senescence as a Contributor to HIV-1-Associated Neurocognitive Disorders
- Senescent Cells Drive Frailty through Systemic Signals
- Changes in the biochemical taste of cytoplasmic and cell-free DNA are major fuels for inflamm-aging
- The association between back muscle characteristics and pressure pain sensitivity in low back pain patients
- Role of pattern recognition receptors of the neurovascular unit in inflamm-aging
- Hepatic potential of Reversed-age Mesenchymal Stem Cells and Endodermal Progenitors: Contribution of LGR5 and Cdc42 cell signaling pathways
- Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis
- Synthetic lethal treatment strategies for tumor cell senescence
- ISEV2018 abstract book
- Aging, Cellular Senescence, and Kidney Fibrosis
- Sex hormones and immunosenescence
- Telomerase may paradoxically accelerate aging of the DNA methylome
- CD36 initiates the secretory phenotype during the establishment of cellular senescence
- A novel in vitro macrophage senescence model to study macrophaging
- A novel in vitro macrophage senescence model to study macrophaging
- Ageing Astrocytes-Implications for Motoneuron Dysfunction and Sarcopenia
- BMP-7: role and regulation in osteoarthritis
- Aging and Malignant Hemopathies: A Complex Multistep Process
- Biomarkers for Identification of the Dormancy Phenotypes Senescence and Quiescence in Malignancy
- Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) and liver fibrosis: A review
- Modulating Ageing Anti-Ageing
- An in vivo and in vitro study of stress-induced senescence in neurones and its role in neurodegeneration
- Gene Expression, Epigenetics and Ageing
- German Congress of Laboratory Medicine: 15th Annual Congress of the DGKL (German Society of Clinical Chemistry and Laboratory Medicine) and the 3rd …
- Aging Mouse Models Reveal Complex Tumor-Microenvironment Interactions in Cancer Progression
- The role of neutrophils in telomere induced senescence via bystander effects
- MITOCHONDRIAL STRESS COMMUNICATION IN MAMMALIAN CELLS
- GATA4-dependent regulation of the secretory phenotype via MCP-1 underlies lamin A-mediated human mesenchymal stem cell aging
- Sirt1 and Parp1 as epigenome safeguards and microRNAs as SASP-associated signals, in cellular senescence and aging
- Exosome-based immunomodulation during aging: a nano-perspective on inflamm-aging
- Leukocyte count, systemic inflammation, and health status in older adults: a narrative review
- Two Conserved Histone H3 Lys9 Demethalases KDM3A and KDM4C Regulate MSCs Senescence Progress
- Nutrient Sensing, Signaling and Ageing: The Role of IGF-1 and mTOR in Ageing and Age-Related Disease
- Identification of HSP90 inhibitors as a novel class of senolytics
- Aging of the Bone
- Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease
- PREMATURE IMMUNOSENESCENCE IN WOMEN NEWLY DIAGNOSED WITH BREAST CANCER–ROLE OF EARLY-LIFE STRESS
- Mitochondria-targeted hydrogen sulfide attenuates endothelial senescence by selective induction of splicing factors HNRNPD and SRSF2
- Sex and the Aging Immune System
- Molecular pathology: the roles of P53 in the oxidative stress and DNA damage responses in chronic liver disease and hepatocellular carcinoma
- A Computational System for Automated Meta-Analysis of Gene Expression Data
- Modulating Aged Macrophages and Osteoprogenitors with a Calcium Phosphate Drug Delivery System
- Examining Autophagy and Mitophagy as Inducible Mechanisms of Cellular Remodelling
- Proteotoxicity links therapy-induced cancer cell senescence to Alzheimer’s disease
- Macrophages in M1/M2 states and exposed to amyloid-beta: a RNA-seq analysis in human cells
- Atorvastatin inhibits inflammatory response, attenuates lipid deposition, and improves the stability of vulnerable atherosclerotic plaques by modulating …
- Werner Syndrome as a Model of Human Aging
- Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and aging
- Cytokine profile of breast cell lines after different radiation doses
- Exercise and circulating factors associated with skeletal muscle and bone health in older age
- Microbiota, NASH, HCC and the potential role of probiotics
- Autophagy and Signaling
- β-Hydroxybutyrate prevents vascular senescence through hnRNP A1-mediated upregulation of Oct4
- Sarcopenia: aging-related loss of muscle mass and function
- Zinc finger protein ZFP36L1 promotes osteoblastic differentiation but represses adipogenic differentiation of mouse multipotent cells
- Elucidating the role of metabolic changes in modulating cell fate following treatment with anti-mitotic drugs
- TGF-β signaling accelerates senescence of human bone-derived CD271 and SSEA-4 double-positive mesenchymal stromal cells
- Progenitor cells from the adult heart
- A rising star in pancreatic diseases: pancreatic stellate cells
- Secretome analysis of testicular peritubular cells as a clue for solving the puzzle of the human spermatogonial stem cell niche
- Functional Identification of MicroRNAs Counteracting Cellular Senescence
- The Geriatrician’s Perspective on Surgery in the Geriatric Population
- Senescence of bone marrow-derived mesenchymal stem cells from patients with idiopathic pulmonary fibrosis
- The Long Noncoding RNA H19 Controls Endothelial Cell Functions by STAT3 Repression
- Clinical Implications for Mitochondrial Stress Induced Senescence and Potential InterventionsS
- The effects of aging in the hippocampus and cognitive decline
- Human Cytomegalovirus as a driving force towards Immunosenescence
- Hematopoietic Stem Cell Aging and Malignant Hemopathies
- Role of Autophagy in Liver Regeneration
- Old age causes de novo intracortical bone remodeling and porosity in mice
- Aging Kidney and Aging-Related Disease
- Melatonin rescued interleukin 1β-impaired chondrogenesis of human mesenchymal stem cells
- Senescence-associated IL-6 and IL-8 cytokines induce a self-and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in …
- Model of Chaperones in Aging
- Senescent Cells Differentially Translate Senescence-Related mRNAs Via Ribosome Heterogeneity
- Accumulation of prelamin A drives inflammation in the heart with implications for treatment of inherited and acquired cardiomyopathies
- Senescence in COPD and its comorbidities
- Characterizing Senescence in Astrocytes and its Effect on Neurons
- Barshop Symposium on Aging 2017 Abstracts
- Role of vascular smooth muscle cell derived-exosomes in age-related vascular amyloidosis
- Cancer metabolism in space and time: beyond the Warburg effect
- Melatonin protected cardiac microvascular endothelial cells against oxidative stress injury via suppression of IP3R-[Ca2+]c/VDAC-[Ca2+]m axis by activation of …
- Tumor Microenvironment, Therapeutic Resistance, and Personalized Medicine
- Liver regeneration in aged mice: new insights
- In medio stat virtus: unanticipated consequences of telomere dysequilibrium
- The contribution of oxidative stress and inflamm-aging in human and equine asthma
- NR4A1 promotes diabetic nephropathy by activating mff-mediated mitochondrial fission and suppressing parkin-mediated mitophagy
- DNA damage induced by Strontium-90 exposure at low concentrations in mesenchymal stromal cells: the functional consequences
- Cardiac ageing: extrinsic and intrinsic factors in cellular renewal and senescence
- Role of primary cilia in non-dividing and post-mitotic cells
- The role of cancer-associated fibroblasts and fibrosis in liver cancer
- Reversibility of chemotherapy-induced senescence is independent of autophagy and a potential model for tumor dormancy and cancer recurrence.
- Cancer Cells Exploit Notch Signaling To Redefine A Tumor Supportive Cytokine Milieu
- Programmed cell senescence in skeleton during late puberty
- Metabolic reprogramming for cancer cells and their microenvironment: Beyond the Warburg Effect
- SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy
- Psychological stress and mitochondria: a conceptual framework
- Immunosenescence and hurdles in the clinical management of older HIV-patients
- Stress granules counteract senescence by sequestration of PAI‐1
- The power behind the throne: senescence and the hallmarks of cancer
- The exercise and diet-microbiome paradigm: influences of physical activity and dietary nutrition on the human gut microbiome
- Empagliflozin rescues diabetic myocardial microvascular injury via AMPK-mediated inhibition of mitochondrial fission
- The functions and regulation of the PTEN tumour suppressor: new modes and prospects
- Distribution and molecular characterization of South African Bacillus Anthracis strains and their associated bacteriophages
- TARGETING ASCT2/SLC1A5 FOR INHIBITION OF CELLULAR GROWTH AND METABOLISM IN TRIPLE-NEGATIVE BREAST CANCER
- Cellular Senescence and Inflammaging in Age-Related Diseases
- The gut microbiome and liver cancer: mechanisms and clinical translation
- BBA-Reviews on Cancer
- RNA Binding Proteins, Ageing and Caloric Restriction
- Controlling senescence by PML and PML nuclear bodies
- Ataxia telangiectasia syndrome: moonlighting ATM
- ER stress and impaired autophagy flux in neuronal degeneration and brain injury
- Leukotriene D4 induces cellular senescence in osteoblasts
- Understanding the Basis of Gene Regulation of Common Complex Diseases by Computational Analysis of Next-generation Sequencing Data
- Matrix stiffness regulates oxidative stress response of human dermal fibroblasts
- Inflammation and the Gut-Liver Axis in the Pathophysiology of Cholangiopathies
- Dendritic Polyglycerol Sulfate Hydrogels as a Potential Viscosupplement for Treatment of Osteoarthritis
- Bile acids and cancer: direct and environmental-dependent effects
- INVOSSATM–a cell and gene therapy for osteoarthritis
- In vitro proinflammatory gene expression predicts in vivo telomere shortening: A preliminary study
- Enhancer function driving cellular senescence, DNA damage repair, differentiation, and nuclear organization
- Investigating strategies to boost cutaneous varicella zoster virus-specific immune responses in ageing humans
- Natural variations in yeast aging reveal genetic and environmental factors
- Circulating levels of soluble Receptor for Advanced Glycation End-products (sRAGE) decrease with aging and may predict age-related cardiac remodeling
- Age-associated metabolic reprogramming, oxidative stress response, and cancer progression
- Impact of age-associated estrogen deficiency on innate immune responses to myocardial ischemic injury in the female rat heart
- Antioxidant and oxidative stress: A mutual interplay in age-related diseases
- MicroRNAs deregulation in prostate cancer
- Vaccination in the elderly: The challenge of immune changes with aging
- From rapalogs to anti-aging formula
- Biomarkers of monitoring and functional reserve of physiological systems over time in HIV: expert opinions for effective secondary prevention
- IDENTIFICATION OF INTRINSIC REGULATORS IN NORMAL AND MALIGNANT HUMAN HEMATOPOIESIS
- Epigenome-wide DNA methylation and mitochondrial DNA content in relation to in utero PM2.5 exposure
- l-Carnitine inhibits the senescence-associated secretory phenotype of aging adipose tissue by JNK/p53 pathway
- adipose tissue, aging, and metabolism
- Growth hormone impact on adipose tissue and aging
- adipose tissue Quality in Aging: How Structural and Functional Aspects of adipose tissue Impact Skeletal Muscle Quality
- Targeting senescent cells alleviates obesity‐induced metabolic dysfunction
- adipose tissue: A Tertiary Lymphoid Organ: Does It Change with Age?
- Age-Dependent and-Independent Effects of Perivascular adipose tissue and Its Paracrine Activities during Neointima Formation
- Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
- Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia
- Heparanase upregulation from adipocyte associates with inflammation and endothelial injury in diabetic condition
- Cellular senescence: at the nexus between ageing and diabetes
- OBESITY INDUCES MESENCHYMAL STEM CELL SENESCENCE AND DYSFUNCTION
- Histologic analysis and lipid profiling reveal reproductive age-associated changes in peri-ovarian adipose tissue
- In vitro model of chronological aging of adipocytes: Interrelationships with hypoxia and oxidation
- Sympathetic nervous system as a target for aging and obesity-related cardiovascular diseases
- Senescent cells in the development of cardiometabolic disease
- Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression
- Relationship between Circulating Protein p53 and High Sensitivity C-Reactive Protein in Central Obesity Men with Inflammaging
- Extracellular fraction of adipose tissue as an innovative regenerative approach for vitiligo treatment
- Normal breast tissue at risk for cancer development: A breast cancer initiating role for mammary adipocytes
- Age-associated inflammation alters the aging trajectory
- Life-span Extension Drug Interventions Affect adipose tissue Inflammation in Aging
- Cellular senescence and senescence‐associated T cells as a potential therapeutic target
- Mitochondrial Uncoupling Protein-2 Is a Putative Link Between Mitochondrial Dysfunction and Fibroblast Senescence in Age-Related Lung Fibrosis
- Lipotoxicity, aging, and muscle contractility: does fiber type matter?
- Skeletal muscle as potential central link between sarcopenia and immune senescence
- Ileal Transposition Increases Pancreatic β Cell Mass and Decreases β Cell Senescence in Diet-Induced Obese Rats
- ALCAT1 Deficiency Attenuates Obesity Induced Cellular Senescence in P16-3MR Transgenic Mice
- Short exposure to cold atmospheric plasma induces senescence in human skin fibroblasts and adipose mesenchymal stromal cells
- Recent advances in understanding tumor stroma-mediated chemoresistance in breast cancer
- Alteration of Hypoxia-Associated Gene Expression in Replicatively Senescent Mesenchymal Stromal Cells under Physiological Oxygen Level
- Rejuvenating Strategies of Tissue-specific Stem Cells for Healthy Aging
- Novel contributors and mechanisms of cellular senescence in hypertension-associated premature vascular aging
- β Cell Senescence as a Common Contributor to Type 1 and Type 2 Diabetes
- Obesity and cancer: A mechanistic overview of metabolic changes in obesity that impact genetic instability
- Age-dependent impairment of adipose-derived stem cells isolated from horses
- Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity?
- Therapeutic Irradiation: Consequences for Bone and Bone Marrow Adipose
- The Role of the Gut Microbiome and its Derived Mediators in Nonalcoholic Fatty Liver Disease
- Inflamm-Aging Is Associated with Lower Plasma PTX3 Concentrations and an Impaired Capacity of PBMCs to Express hTERT following LPS Stimulation
- Impaired immunomodulatory ability of type 2 diabetic adipose-derived mesenchymal stem cells in regulation of inflammatory condition in mixed leukocyte …
- 3D printing breast tissue models: A review of past work and directions for future work
- Aged‐senescent cells contribute to impaired heart regeneration
- Chemotherapy-induced cellular senescence suppresses progression of Notch-driven T-ALL
- Senescent cells: A new Achilles’ heel to exploit for cancer medicine?
- The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD+ decline
- Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing
- The burden of metabolic syndrome on osteoarthritic joints
- Modulation of senoinflammation by calorie restriction based on biochemical and Omics big data analysis
- Remodeling the Microenvironment before Occurrence and Metastasis of Cancer
- Immune senescence and cardiomyopathy associated with obesity
- The role of cellular senescence in diabetes mellitus and osteoporosis: molecular pathways and potential interventions
- Filamin B and CD13 Are Components of Senescent Secretomes That May Be Involved in Primary (Stress Induced) and Paracrine Senescence of Mesenchymal …
- and Ahmet Turan Isik
- β‐Cell senescence in the pathogenesis of type 2 diabetes
- Inflammation, Frailty and Cardiovascular Disease
- Cellular Senescence in the Kidney
- Heat shock response to exercise in pancreatic islets of obese mice
- Regulation of senescence and the SASP
- The Links Between Osteoporosis and Sarcopenia in Women
- Increased renal cellular senescence in murine high-fat diet: effect of the senolytic drug quercetin
- Type 2 diabetes is associated with the accumulation of senescent T cells
- Elimination of senescent osteoclast progenitors has no effect on the age‐associated loss of bone mass in mice
- Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38+ pro-inflammatory macrophages
- Adipokines: New Therapeutic Target for Osteoarthritis?
- Major depression and enhanced molecular senescence abnormalities in young and middle-aged adults
- Expansion and cell-cycle arrest: Common denominators of cellular senescence
- Mechanisms of obesity-induced metabolic and vascular dysfunctions
- Redefining Chronic Inflammation in Aging and Age-Related Diseases: Proposal of the Senoinflammation Concept
- Mixing old and young: enhancing rejuvenation and accelerating aging
- Involvement of adiponectin in age-related increases in tear production in mice
- LPS-induced premature osteocyte senescence: Implications in inflammatory alveolar bone loss and periodontal disease pathogenesis
- Emerging roles of and therapeutic strategies targeting BRD4 in cancer
- In situ evidence of cellular senescence in Thymic Epithelial Cells (TECs) during human thymic involution
- Cellular senescence in bone
- Effect of aging on behaviour of mesenchymal stem cells
- Earlier changes in mice after D-galactose treatment were improved by mitochondria derived small peptide MOTS-c
- Pleiotropic effect of fibrates on senescence and autophagy in osteoarthritis
- Low-dose quercetin positively regulates mouse healthspan
- Microbial metabolites in non-alcoholic fatty liver disease
- Elevated Local Senescence in Diabetic Wound Healing Is Linked to Pathological Repair via CXCR2
- The potential role of senescence in limiting fibrosis caused by aging
- Metabolic Alterations in Aging Macrophages: Ingredients for Inflammaging?
- Protective role of polyphenols against vascular inflammation, aging and cardiovascular disease
- TGF-β Signaling in Cellular Senescence and Aging-Related Pathology
- Obesity-induced cellular senescence drives anxiety and impairs neurogenesis
- Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells
- Targeting normal and cancer senescent cells as a strategy of senotherapy
- Senescent and apoptotic osteocytes and aging: Exercise to the rescue?
- Senotherapeutics: Emerging strategy for healthy aging and age-related disease
- Extracellular vesicles circulating in young organisms promote healthy longevity
- Effectiveness of stage by stage bariatric interventions for regression of comorbidity at obese class III patients
- L1 drives IFN in senescent cells and promotes age-associated inflammation
- The STATus of STAT3 in Lung Cell Senescence?
- Intraarticular senescent chondrocytes impair the cartilage regeneration capacity of mesenchymal stem cells
- Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix‐related gene expression partly via secretion of complement factor D
- Mitochondria and cellular senescence: Implications for musculoskeletal ageing
- Age and Frailty as Risk Factors for the Development of Osteoarthritis
- The biology of frailty in humans and animals: Understanding frailty and promoting translation
- Turning back time with emerging rejuvenation strategies
- Senescence and senotherapeutics: A new field in cancer therapy
- Senescence marker activin A is increased in human diabetic kidney disease: association with kidney function and potential implications for therapy
- The Safe and Efficacious Use of Secretome From Fibroblasts and Adipose-derived (but not Bone Marrow-derived) Mesenchymal Stem Cells for Skin …
- Cellular Senescence and the Immune System in Cancer
- Advanced liver steatosis accompanies an increase in hepatic inflammation, colonic, secondary bile acids and Lactobacillaceae/Lachnospiraceae bacteria in C57BL/6 …
- KRAS, YAP, and obesity in pancreatic cancer: A signaling network with multiple loops
- Chronic inflammation in the etiology of disease across the life span
- Pan-senescence transcriptome analysis identified RRAD as a marker and negative regulator of cellular senescence
- Flavonoids: Broad Spectrum Agents on Chronic Inflammation
- Astrocyte senescence in an Alzheimer’s disease mouse model is mediated by TGF-β1 and results in neurotoxicity
- mTOR as a central regulator of lifespan and aging
- Vascular Diseases and Gangliosides
- Muscle-derived miR-34a increases with age in circulating extracellular vesicles and induces senescence of bone marrow stem cells
- Aging and lineage allocation changes of bone marrow skeletal (stromal) stem cells
- Looking for immortality: Review of phytotherapy for stem cell senescence
- Gangliosides Contribute to Vascular Insulin Resistance
- Emerging senolytic agents derived from natural products
- Vitamin E: Regulatory Role on Signal Transduction
- Experimental strategies of mesenchymal stem cell propagation: Adverse events and potential risk of functional changes
- Introductory Chapter: Nonalcoholic Fatty Liver Disease-What Should We Know?
- The role of probiotics in nonalcoholic fatty liver disease: a new insight into therapeutic strategies
- Cellular senescence and chronological age in various human tissues: A systematic review and meta‐analysis
- Nrf2 exerts mixed inflammation and glucose metabolism regulatory effects on murine RAW264. 7 macrophages
- Chronic Low-grade Inflammatory Phenotype (CLIP) and Senescent Immune Dysregulation
- Obesity May Accelerate the Aging Process
- Manufacturing of primed mesenchymal stromal cells for therapy
- Pyrroloquinoline quinone prevents estrogen deficiency-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence
- Obesity is a common soil for premature cardiac aging and heart diseases-role of autophagy
- Culinary medicine: advancing a framework for healthier eating to improve chronic disease management and prevention
- Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development
- Senescence in the lung: is this getting old?
- TGF-β mediates aortic smooth muscle cell senescence in Marfan syndrome
- Cellular senescence in cardiac diseases
- Bone marrow niches for skeletal progenitor cells and their inhabitants in health and disease
- Potential role of senescence in radiation-induced damage of the aged skeleton
- The kynurenine pathway: a finger in every pie
- Cell aging and cellular senescence in skin aging—Recent advances in fibroblast and keratinocyte biology
- The Senescent Cell, SC
- Mitochondria-driven elimination of cancer and senescent cells
- Use of MSCs in Antiaging Strategies
- Dynamic role of the codon 72 p53 single-nucleotide polymorphism in mammary tumorigenesis in a humanized mouse model
- Promotion and induction of liver cancer by gut microbiome-mediated modulation of bile acids
- Cellular cross-talks in the diseased and aging heart
- Conditioned Medium of Mesenchymal Stromal Cells: A New Class of Therapeutics
- Coexisting frailty with heart failure
- Barshop Symposium on Aging 2018 Abstracts
- Amitosenescence and Pseudomitosenescence: Putative New Players in the Aging Process
- HIF1α‐mediated AIMP3 suppression delays stem cell aging via the induction of autophagy
- Inflammaging as a common ground for the development and maintenance of sarcopenia, obesity, cardiomyopathy and dysbiosis
- Inflammation: a common contributor to cancer, aging, and cardiovascular diseases—expanding the concept of cardio-oncology
- Inflammation as a mediator of arterial ageing
- LINE-1 derepression in senescent cells triggers interferon and inflammaging
- Cells exhibiting strong p16INK4a promoter activation in vivo display features of senescence
- Early vascular ageing and cellular senescence in chronic kidney disease
- Childhood obesity and leucocyte telomere length
- Cell-Free Culture Supernatant of Probiotic Lactobacillus fermentum Protects Against H2O2-Induced Premature Senescence by Suppressing ROS-Akt-mTOR Axis in …
- Raman fingerprints as promising markers of cellular senescence and aging
- Where Metabolism Meets Senescence: Focus on Endothelial Cells
- Exercise Training for the Elderly: Inflammaging and the Central Role for HSP70
- Proteomic analysis of human mesenchymal stromal cell secretomes: a systematic comparison of the angiogenic potential
- BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome
- Quantifying Senescence-Associated Phenotypes in Primary Multipotent Mesenchymal Stromal Cell Cultures
- Roles of JAK2 in aging, inflammation, hematopoiesis and malignant transformation
- Independent Roles of Estrogen Deficiency and Cellular Senescence in the Pathogenesis of Osteoporosis: Evidence in Young Adult Mice and Older Humans
- Cellular senescence in arterial diseases
- 25-Hydroxyvitamin D3 positively regulates periodontal inflammaging via SOCS3/STAT signaling in diabetic mice
- Inflammation, Infection and Atherosclerosis
- Obesity-Associated Hypermetabolism and Accelerated Senescence of Bone Marrow Stromal Stem Cells Suggest a Potential Mechanism for Bone Fragility
- Chronic whole-body heat treatment relieves atherosclerotic lesions, cardiovascular and metabolic abnormalities, and enhances survival time restoring the anti …
- The chemistry of senescence
- Stem Cell Senescence: the Obstacle of the Treatment of Degenerative Disk Disease
- Autophagy Dysfunction, Cellular Senescence, and Abnormal Immune-Inflammatory Responses in AMD: From Mechanisms to Therapeutic Potential
- Breast tissue biology expands the possibilities for prevention of age-related breast cancers
- Senescent cell clearance by the immune system: Emerging therapeutic opportunities
- Metformin and Aging: A Review
- Non-Alcoholic Fatty Liver Disease, and the Underlying Altered Fatty Acid Metabolism, Reveals Brain Hypoperfusion and Contributes to the Cognitive Decline in APP …
- Senile Osteoporosis: The Involvement of Differentiation and Senescence of Bone Marrow Stromal Cells
- Muscle and Bone Biology–Similarities and Differences
- COPD as a Disease of Immunosenescence
- Sex hormones and anticancer immunity
- Targeting chronic innate inflammatory pathways, the main road to prevention of osteoarthritis progression
- Autofluorescence is a Reliable in vitro Marker of Cellular Senescence in Human Mesenchymal Stromal Cells
- Methionine restriction delays senescence and suppresses the senescence-associated secretory phenotype in the kidney through endogenous hydrogen sulfide
- Identification of Aberrantly Expressed Genes during Aging in Rat Nucleus Pulposus Cells
- Role of the Gut–Liver Axis in Liver Inflammation, Fibrosis, and Cancer: A Special Focus on the Gut Microbiota Relationship
- Type 2 diabetes: how much of an autoimmune disease?
- Urine-Derived Stem Cells Secreting Small Extracellular Vesicles Loaded in Acellular Amniotic Membrane for Wound Healing Promotion in Aged Mice
- Type 2 Diabetes: How Much of an Autoimmune Disease?
- Fasting and rapamycin: diabetes versus benevolent glucose intolerance
- Roles of the Immune System in the Development and Progression of Hepatocellular Carcinoma
- Genetic Stability of Mesenchymal Stromal Cells for Regenerative Medicine Applications: A Fundamental Biosafety Aspect
- Regulation of cellular senescence by retinoid X receptors and their partners
- Secretome of Mesenchymal Stem Cells and its Impact on Chronic Obstructive Pulmonary Disease
- Defective induction of the proteasome associated with T‐cell receptor signaling underlies T‐cell senescence
- Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
- When the skin is in the center of interest-An aging issue
- New frontiers in osteoporosis therapy
- Aging and Cardiovascular Diseases: The Role of Cellular Senescence
- Oxidative Stress and Non-Alcoholic Fatty Liver Disease: Effects of Omega-3 Fatty Acid Supplementation
- Efficacy of 3D Culture Priming is Maintained in Human Mesenchymal Stem Cells after Extensive Expansion of the Cells
- Potential Mechanisms of 3, 4-Oxo-Isopropylidene-Shikimic Acid in Ameliorating 2, 4, 6-Trinitrobenzenesulfonic Acid-Induced Colitis in Rats
- Principal Criteria for Evaluating the Quality, Safety and Efficacy of hMSC-Based Products in Clinical Practice: Current Approaches and Challenges
- The clinical impact and biological mechanisms of skeletal muscle aging
- Chronic Kidney Disease and the Vascular Endothelium
- Current Knowledge and New Challenges in Exercise Immunology
- Aspirin ameliorates the long‐term adverse effects of doxorubicin through suppression of cellular senescence
- Aging, Immunity, and Neuroinflammation: The Modulatory Potential of Nutrition
- Perspectives of the International Society of Cell & Gene Therapy Gastrointestinal Scientific Committee on the Intravenous Use of Mesenchymal Stromal Cells in …
- Cellular senescence: aging, cancer, and injury
- Searching for the Holy Grail Will Need Biomarkers
- DNA damage response manages cell cycle restriction of senile multipotent mesenchymal stromal cells
- The role of mitochondria-derived peptides in cardiovascular disease: Recent updates
- Tackling Aging by Using miRNA as a Target and a Tool
- Selective elimination of senescent cells by mitochondrial targeting is regulated by ANT2
- Premature aging and cancer development in transgenic mice lacking functional CYLD
- Obesity-Induced Sympathoexcitation is Associated with Nrf2 Dysfunction in the Rostral VentroLateral Medulla
- Senescence‐induced immunophenotype, gene expression and electrophysiology changes in human amniocytes
- The senescence-associated secretory phenotype and its regulation
- An early‐senescence state in aged mesenchymal stromal cells contributes to hematopoietic stem and progenitor cell clonogenic impairment through the activation of a …
- Extracellular vesicles and redox modulation in aging
- Survival of aging CD264+ and CD264− populations of human bone marrow mesenchymal stem cells is independent of colony‐forming efficiency
- Seno-suppressive molecules as new therapeutic perspectives in rheumatic diseases
- Identification of senescent cells in multipotent mesenchymal stromal cell cultures: current methods and future directions
- The ING1a model of rapid cell senescence
- The key players of tumor microenvironment and their role in breast cancer
- Skin barrier immunity and ageing
- Integration of heterogeneous functional genomics data in gerontology research to find genes and pathway underlying aging across species
- Metabolic requirements of human pro-inflammatory B cells in aging and obesity
- Aging and bone
- Control of Inflammation by Calorie Restriction Mimetics: On the Crossroad of Autophagy and Mitochondria
- PGC1α repression in IPF fibroblasts drives a pathologic metabolic, secretory and fibrogenic state
- Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming☆
- The Molecular Physiology of Ageing: New Targets for Regenerative Medicine
- Knockdown of angiopoietin-like 2 induces clearance of vascular endothelial senescent cells by apoptosis, promotes endothelial repair and slows …
- Obesity and Hepatocarcinogenesis
- Lifestyle Choices, Psychological Stress and Their Impact on Ageing: The Role of Telomeres
- Mechanisms of Calorie Restriction: A Review of Genes Required for the Life-Extending and Tumor-Inhibiting Effects of Calorie Restriction
- Exosomes may be the potential new direction of research in osteoarthritis management
- Mitochondrial protection partly mitigates kidney cellular senescence in swine atherosclerotic renal artery stenosis
- Molecular insights into Hutchinson-Gilford progeria syndrome and age-associated disease: from mechanisms to treatment strategy
- Rapid detection of senescent mesenchymal stromal cells by a fluorescent probe
- Iron and iron-dependent reactive oxygen species in the regulation of macrophages and fibroblasts in non-healing chronic wounds
- Low‐Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro
- Maternal Sleep in Pregnancy and Postpartum Part II: Biomechanisms and Intervention Strategies
- Hydroxyurea‐induced Senescent Peripheral Blood Mesenchymal Stromal Cells Inhibit Bystander Cell Proliferation of JAK2V617F‐positive Human Erythroleukemia …
- Doxorubicin and liposomal doxorubicin induce senescence by enhancing nuclear factor kappa B and mitochondrial membrane potential
- The Upregulation of Toll-Like Receptor 3 via Autocrine IFN-β Signaling Drives the Senescence of Human Umbilical Cord Blood-Derived Mesenchymal Stem …
- Myeloid-derived suppressor cells: not only in tumor immunity
- Moderate hyperoxia induces senescence in developing human lung fibroblasts
- Senolytics and senostatics as adjuvant tumour therapy
- The link between endometrial stromal cell senescence and decidualization in female fertility: the art of balance
- Melatonin attenuates renal fibrosis in diabetic mice by activating the AMPK/PGC1α signaling pathway and rescuing mitochondrial function
- Molecular taxonomy of osteoarthritis for patient stratification, disease management and drug development: biochemical markers associated with emerging clinical …
- Differential Expression of Human N-Alpha-Acetyltransferase 40 (hNAA40), Nicotinamide Phosphoribosyltransferase (NAMPT) and Sirtuin-1 (SIRT-1) Pathway …
- Regulation of inflammation as an anti‐aging intervention
- Aiding and Abetting: How the Tumor Microenvironment Protects Cancer from Chemotherapy
- Relationships between ion channels, mitochondrial functions and inflammation in human aging
- Targeting senescent cells in translational medicine
- Recent insights into the multiple pathways driving nonalcoholic steatohepatitis-derived hepatocellular carcinoma
- Aging, sex, inflammation, frailty, and CMV and HIV Infections
- Low-grade inflammation causes gap junction-coupled cell dysfunction throughout the body, which can lead to the spread of systemic inflammation
- The upregulation of Toll-like receptor 3 via autocrine IFN-beta signaling drives the senescence of human mesenchymal stem cells through JAK1
- Pak2 kinase promotes cellular senescence and organismal aging
- Molecular Pathogenesis of Oral Submucous Fibrosis: A Critical Appraisal
- Mechanisms of aging and potential role of selected polyphenols in extending healthspan
- The role of lipids in aging-related metabolic changes
- Emerging Role of Stem cell-derived Extravesicular MicroRNAs in Age-associated Human Diseases and in Different Therapies of Longevity
- The genetics of human ageing
- Inflammation in osteoarthritis: is it time to dampen the alarm (in) in this debilitating disease?
- Estrogen deprivation triggers an immunosuppressive phenotype in breast cancer cells
- Liver and Steroid Hormones—Can a Touch of p53 Make a Difference?
- Impacts of the late adulthood diet-induced obesity onset on behavior, immune function, redox state and life span of male and female mice
- The Mediterranean Diet Slows Down the Progression of Aging and Helps to Prevent the Onset of Frailty: A Narrative Review
- Exosome: Advanced Development and a Novel Therapeutic Strategy for Osteoarthritis and Cartilage Injury
- Diabetes drugs in the fight against Alzheimer’s disease
- Patient-Derived Organoids from Human Bile: An In Vitro Method to Study Cholangiopathies
- The Aging Thyroid: A Reappraisal Within the Geroscience Integrated Perspective
- Immune Modulation by Transplanted Calcium Phosphate Biomaterials and Human Mesenchymal Stromal Cells in Bone Regeneration
- Bone marrow-derived mesenchymal stem cells in three-dimensional co-culture attenuate degeneration of nucleus pulposus cells
- Roles of sleep deprivation in cardiovascular dysfunctions
- micro (RNA)-managing muscle wasting
- Stem cell derived exosomes: microRNA therapy for age-related musculoskeletal disorders
- Astrocyte senescence: Evidence and significance
- FGF21 Mediates Mesenchymal Stem Cell Senescence via Regulation of Mitochondrial Dynamics
- Aging and the Biological Response to Liver Injury
- Age-Related Thymic Atrophy: Mechanisms and Outcomes
- The Effects of Early-Life Drug and Dietary Interventions on Late-Life Disease Development
- Preclinical Evidence for the Role of Stem/Stromal Cells in COPD
- Melatonin attenuates myocardial ischemia‐reperfusion injury via improving mitochondrial fusion/mitophagy and activating the AMPK‐OPA1 signaling pathways
- Therapeutic effect of n-butanol fraction of Huang-lian-Jie-du Decoction on ulcerative colitis and its regulation on intestinal flora in colitis mice
- Future Cell and Gene Therapy for Osteoarthritis (OA): Potential for Using Mammalian Protein Production Platforms, Irradiated and Transfected Protein …
- Gut microbiota in liver disease: too much is harmful, nothing at all is not helpful either
- Embryonic stem cell-derived extracellular vesicles enhance the therapeutic effect of mesenchymal stem cells
- Tumor microenvironment-driven non-cell-autonomous resistance to antineoplastic treatment
- Pharmacology of metformin–An update
- Restoring mechano-adaptation in aged murine bone
- Slowing Down Ageing: The Role of Nutrients and Microbiota in Modulation of the Epigenome
- Integrating cellular senescence with the concept of damage accumulation in aging: Relevance for clearance of senescent cells
- Mechanistic complexities of bone loss in Alzheimer’s disease: a review
- Investigation on Spectrum-Effect Correlation between Constituents Absorbed into Blood and Bioactivities of Baizhu Shaoyao San before and after Processing on …
- Lifelong aerobic exercise protects against inflammaging and cancer
- Distinct effects of epirubicin, cisplatin and cyclophosphamide on ovarian somatic cells of prepuberal ovaries
- The Emerging Role of Exosomal Non-coding RNAs in Musculoskeletal Diseases
- Mitochondria in the signaling pathways that control longevity and health span
- Crosstalk between P53 and DNA Damage Response in Ageing
- Diabetic gut microbiota dysbiosis as an inflammaging and immunosenescence condition that fosters progression of retinopathy and nephropathy
- Dual faced HMGB1 plays multiple roles in cardiomyocyte senescence and cardiac inflammatory injury
- Melatonin and chromatin
- Mst1 facilitates hyperglycemia-induced retinal pigmented epithelial cell apoptosis by evoking mitochondrial stress and activating the Smad2 signaling pathway
- Circular RNA CircCCNB1 sponges micro RNA-449a to inhibit cellular senescence by targeting CCNE2
- Failure of immunosurveillance accelerates aging
- Rationally-based therapeutic disease modification in systemic sclerosis: Novel strategies
- Extracellular vesicles in human skin: cross-talk from senescent fibroblasts to keratinocytes by miRNAs
- Pharmacodynamics OF TNF α inhibitors for the treatment of psoriasis
- Integrated Theories of Biological Aging
- Organismal Aging and Oxidants Beyond Macromolecules Damage<? Qry msg=” Please provide author biographies for up to three authors (each biography not …
- The Role of Curcumin in the Modulation of Ageing
- The Impending Epidemic of Cardiovascular Diseases in Patients With Cancer in Japan
- Pro-and anti-tumorigenic functions of the senescence-associated secretory phenotype
- Silencing of long noncoding RNA HOXA11-AS inhibits the Wnt signaling pathway via the upregulation of HOXA11 and thereby inhibits the proliferation …
- Novel clinico-molecular insights into the role of bisphenol-A (BPA) in the etiology of diabetes
- Mitochondria and aging—The role of exercise as a countermeasure
- A novel form of Deleted in breast cancer 1 (DBC1) lacking the N-terminal domain does not bind SIRT1 and is dynamically regulated in vivo
- INJURY SENESCENCE OF THE IMMUNE SYSTEM
- Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and XIAP
- Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons
- Moving beyond the current limits of data analysis in longevity and healthy lifespan studies
- Cellular senescence and the kidney: potential therapeutic targets and tools
- The Biology of Senescence
- The clock is ticking: the impact of ageing on T cell metabolism
- Ribosomal DNA instability: an evolutionary conserved fuel for inflammaging
- Role of microRNA-141 in the aging musculoskeletal system: a current overview
- Activation of immunosuppressive network in the aging process
- Senescence cell–associated extracellular vesicles serve as osteoarthritis disease and therapeutic markers
- Molecular biology of acute and chronic inflammation
- Transcriptomic analysis reveals the mechanism of sulfasalazine-induced liver injury in mice
- Inflammatory bone marrow microenvironment
- Cell and Gene Therapy for Spine Regeneration: Mammalian Protein Production Platforms for Overproduction of Therapeutic Proteins and Growth Factors
- Interleukin-17 and senescence regulate the foreign body response
- Nuclear-encoded Mitochondrial Genetic Variation in Human Aging and Longevity
- Transient introduction of human telomerase mRNA improves hallmarks of progeria cells
- DNA Damage Induced Cell Fates during Aging
- Chromosomal instability and pro-inflammatory response in aging
- Understanding the role of chondrocytes in osteoarthritis: utilizing proteomics
- Emerging Roles of Complement Protein C1q in Neurodegeneration
- Growth hormone in the tumor microenvironment
- NAD+ Metabolism in Aging and Cancer
- Cellular Stress and General Pathological Processes
- A prospect of cell immortalization combined with matrix microenvironmental optimization strategy for tissue engineering and regeneration
- The expression of P16 and S100 associated with elastin degradation and fibrosis of the Ligamentum Flavum hypertrophy
- Risk Factors for Frailty and Cardiovascular Diseases: Are They the Same?
- MicroRNAs in the Functional Defects of Skin Aging
- Aging, Melatonin, and the Pro-and Anti-Inflammatory Networks
- Huang-Lian-Jie-Du decoction ameliorates acute ulcerative colitis in mice via regulating NF-κB and Nrf2 signaling pathways and enhancing intestinal barrier function
- Cellular senescence in cultured human brainstem astrocytes: Effect of oxidative stress
- A murine aging cell atlas reveals cell identity and tissue-specific trajectories of aging
- Exosomal long noncoding RNAs in aging and age‐related diseases
- Cellular senescence in the lung across the age spectrum
- Modulation of Human Neutrophil Peptides on P. aeruginosa Killing, Epithelial Cell Inflammation and Mesenchymal Stromal Cell Secretome Profiles
- Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis
- Alpha-1 Antitrypsin Deficiency and Accelerated Aging: A New Model for an Old Disease?
- ERR agonism reverses mitochondrial dysfunction and inflammation in aging
- Senescent hepatocytes in decompensated liver show reduced UPRMT and its key player, CLPP, attenuates senescence in vitro
- Thrombin Induces Angiotensin II-Mediated Senescence in Atrial Endothelial Cells: Impact on Pro-Remodeling Patterns
- Preventive role of Resveratrol against inflammatory cytokines and related diseases
- Towards a unified mechanistic theory of aging
- Iguratimod: a valuable remedy from the Asia Pacific region for ameliorating autoimmune diseases and protecting bone physiology
- Autophagy and Immune Tolerance
- Investigating the role of microRNAs in the hypoxic response in prostate cancer
- Clinical Inference of Serum and Bone Sclerostin Levels in Patients with End-Stage Kidney Disease
- Healthy aging: A bibliometric analysis of the literature
- Danger signals and inflammaging in osteoarthritis
- Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence
- Orexins as novel therapeutic targets in inflammatory and neurodegenerative diseases
- Skin Health from the Inside Out
- SFRR-E 2019 ANNUAL MEETING “REDOX HOMEOSTASIS: FROM SIGNALING TO DAMAGE”
- Oleuropein, a Bioactive Compound from Olea europaea L., as a Potential Preventive and Therapeutic Agent in Non-Communicable Diseases
- Interleukin-1 and related cytokines in the regulation of inflammation and immunity
- Plenary Sessions
- Premature aging syndromes: From patients to mechanism
- Understanding the origin and diversity of macrophages to tailor their targeting in solid cancers
- Oxytocin Alleviates Cellular Senescence through Oxytocin Receptor‐Mediated ERK/Nrf2 Signalling
- Inflammation and cancer: triggers, mechanisms, and consequences
- Probiotic bacteria as modulators of cellular senescence: emerging concepts and opportunities
- Immunobiology of atherosclerosis: a complex net of interactions
- Beneficial effect of physical exercise on telomere length and aging, and genetics of aging-associated noncommunicable diseases
- Inflammaging and oxidative stress in human diseases: from molecular mechanisms to novel treatments
- Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis
- Methylglyoxal Acts as a Tumor-Promoting Factor in Anaplastic Thyroid Cancer
- The potential role of necroptosis in inflammaging and aging
- Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories
- Enhancement of epithelial cell autophagy induced by sinensetin alleviates epithelial barrier dysfunction in colitis
- Age-related inflammation triggers skeletal stem/progenitor cell dysfunction
- Quantitative proteomic analyses in blood: A window to human health and disease
- The bystander effect contributes to the accumulation of senescent cells in vivo.
- Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells
- Antioxidative nanomaterials and biomedical applications
- Health Benefits of Anti-aging Drugs
- Exercise and dietary interventions in a rat model of metabolic knee osteoarthritis
- Tissue Engineering and Regenerative Medicine Therapies for Cell Senescence in Bone and Cartilage
- Placental Ageing in Adverse Pregnancy Outcomes: Telomere Shortening, Cell Senescence, and Mitochondrial Dysfunction
- Regulatory mechanisms and clinical manifestations of musculoskeletal aging
- Sex Steroids, Cognate Receptors, and Aging
- Epigenetic changes during aging and their reprogramming potential
- NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis
- Premature cell senescence in human skin: dual face in chronic acquired pigmentary disorders
- 140-3D Hydrogels and Bioinks for Realistic In Vitro Modelling and Bioprinting
- Impact of aging on bone, marrow and their interactions
- FRI0531 THE ARTICULAR PROTECTION EFFECT OF ISORHAMNETIN IN THE RATS OF MONOSODIUM IODOACETATE-INDUCED OSTEOARTHRITIS
- Benefits of tree nuts consumption on aging and age-related diseases: mechanisms of actions
- Regulation of Wound Healing by the NRF2 Transcription Factor—More Than Cytoprotection
- Enhancement of therapeutic efficacy by immunomodulation in human mesenchymal stem cells
- PAK4 signaling in development and cancer
- Transposable Elements, Inflammation and Neurological Disease
- Drugs that target aging: how do we discover them?
- Extracellular matrix roles in cardiorenal fibrosis: Potential therapeutic targets for CVD and CKD in the elderly
- Murine models of accelerated aging and musculoskeletal disease
- Identification of differentially expressed transcription factors and dissecting the role of DREAM complex associated components in cellular senescence
- Inflammation and Liver Cancer: Molecular Mechanisms and Therapeutic Targets
- Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model
- Acquired Immune Response to Infection
- MHY2233 Attenuates Replicative Cellular Senescence in Human Endothelial Progenitor Cells via SIRT1 Signaling
- Methods to Quantify the NF-κB Pathway During Senescence
- Somatic mutations in healthy cells and age-associated diseases
- HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity
- Investigating the immune system in chrONIC kidney disease-the SONIC study
- JOINT MEETING AGI–SIMAG
- Rejuvenation: Turning back the clock of aging kidney
- Characterisation of an in vitro aged cell culture model
- L1CAM and its role in cellular senescence
- The role of the cell-matrix interface in aging and its interaction with the renin-angiotensin system in the aged vasculature
- Time for the systems-level integration of aging: Resilience enhancing strategies to prevent Alzheimer’s disease
- Epigenetics and Pharmacoepigenetics of Age-Related Neurodegenerative Disorders
- Molecular basis of senescence transmitting in the population of human endometrial stromal cells
- Shared and distinct mechanisms of fibrosis
- Skeletal Muscle Stem Cells
- Are There Reliable Biomarkers for Immunosenescence and Inflammaging?
- Epidermal growth factor (EGF) intralesional infiltrations: from the bench to the diabetic ulcers cells
- Senescence surveillance: the interplay between the immune system and senescent cells
- Exosomes as Emerging Pro-Tumorigenic Mediators of the Senescence-Associated Secretory Phenotype
- Age-Associated Changes in the Immune System and Blood–Brain Barrier Functions
- Recent advances in understanding the phenotypes of osteoarthritis
- Inducing Age Related Changes in Microglia as a Model for Neurodegenerative Disease
- Convallatoxin protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB signaling through activation of PPARγ
- Innate immune cell crosstalk induces melanoma cell senescence
- Characterization and Analysis of Neural Progenitor Cells from Primary Progressive Multiple Sclerosis Patients
- Targeting Cell Senescence for the Treatment of Age-Related Bone Loss
- Ell3 functions as a critical decision maker at the crossroad between stem cell senescence and apoptosis
- The role of exosomes in regenerative medicine
- Mitochondrial dysfunction and cell senescence: deciphering a complex relationship
- The Effects of IL-1β on Astrocytes are Conveyed by Extracellular Vesicles and Influenced by Age
- The role of senescence in cancer development
- 41th Volume Index
- The proteome of ulcerative colitis-Functional analyses of the active disease and the remission state in comparison with healthy controls
- Allostatic load and ageing: linking the microbiome and nutrition with age-related health
- Rosiglitazone ameliorates senescence and promotes apoptosis in ovarian cancer induced by olaparib
- Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with …
- Methods for CPP Functionalization
- Probing the impact of the maternal environment on foetal development: Can high-resolution telomere analysis predict prenatal adversity?
- Bone marrow stromal cells from β-thalassemia patients have impaired hematopoietic supportive capacity
- Recurrent circadian fasting (RCF) improves blood pressure, biomarkers of cardiometabolic risk and regulates inflammation in men
- Noncoding RNAs: Bridging Regulation of Circadian Rhythms and Inflammation
- Accelerated cardiomyocyte senescence contributes to late-onset doxorubicin-induced cardiotoxicity.
- SEXUAL ABUSE: HOW CAN WE KNOW?
- Metabolic phenotyping of the human microbiome
- Reduced RNA turnover as a driver of cellular senescence
- The role of metabolism in the anti-tumor cytotoxicity of natural killer cells
- Microncronucleus index in epithelial exfoliated cells of urothelium and buccal mucosa, and peripheral blood lymphocytes of patients with papillary urothelial …
- Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells
- Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and cartilage regeneration in osteoarthritis
- PTEN loss regulates alveolar epithelial cell senescence in pulmonary fibrosis depending on Akt activation
- Mitophagy, Mitochondrial Dynamics, and Homeostasis in Cardiovascular Aging
- TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis—Updated 2019
- Know your enemy: Genetics, aging, exposomic and inflammation in the war against triple negative breast cancer
- NAD+ in brain aging and neurodegenerative disorders
- Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies
- miR-140 Attenuates the Progression of Early-Stage Osteoarthritis by Retarding Chondrocyte Senescence
- The dark side of fibroblasts: cancer-associated fibroblasts as mediators of immunosuppression in the tumor microenvironment
- The role of signaling pathways of inflammation and oxidative stress in development of senescence and aging phenotypes in cardiovascular disease
- Emerging targets of disease-modifying therapy for systemic sclerosis
- Identification and characterization of inter-species aging-related transcriptomic regulators
- Mouse Models of Accelerated Cellular Senescence
- Cranberries–potential benefits in patients with chronic kidney disease
- Mitochondrial Homeostasis and Cellular Senescence
- Amelioration of age‐related brain function decline by Bruton’s tyrosine kinase inhibition
- NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice
- Paeonol prevents IL-1β-induced inflammatory response and degradation of type II collagen in human primary chondrocytes
- Scarless wound healing: From development to senescence
- β cell responses to inflammation
- The modular proteome and its significance
- Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies
- Ferroptosis, a new form of cell death: opportunities and challenges in cancer
- Senescence-associated metabolomic phenotype in primary and iPSC-derived mesenchymal stromal cells
- Leukocyte Telomere Length in Patients with Radiographic Knee Osteoarthritis
- Concepts in Inflammatory Bowel Disease Management
- Protein Signatures of Centenarians and Their Offspring Suggest Centenarians Age Slower than Other Humans
- Tumor microenvironment: Interactions and therapy
- The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1
- Stromal cell-derived factor-1 (CXCL12) and its role in bone and muscle biology
- Measuring biological aging in humans: A quest
- Amelioration of Ductular Reaction by Stem Cell Derived Extracellular Vesicles in MDR2 Knockout Mice via Lethal‐7 microRNA
- Activation of melatonin receptor 2 but not melatonin receptor 1 mediates melatonin‐conferred cardioprotection against myocardial ischemia/reperfusion injury
- Proteomic Markers for Depression
- Induction of Fibroblast Senescence During Mouse Corneal Wound Healing
- Regulation of Thirst and Vasopressin Release
- Hyper-osmolarity environment-induced oxidative stress injury promotes nucleus pulposus cell senescence in vitro
- Novel drug targets in idiopathic pulmonary fibrosis
- Sleep, stress, and immunity
- Meeting report: Metastasis Research Society (MRS) 17th Biennial conference and associated Young Investigator Satellite Meeting (YISM) on cancer metastasis
- Targeting pro-senescence mitogen activated protein kinase (Mapk) enzymes with bioactive natural compounds
- Coordination of immune-stroma crosstalk by IL-6 family cytokines
- Long non-coding RNA CDKN2B-AS1 reduces inflammatory response and promotes cholesterol efflux in atherosclerosis by inhibiting ADAM10 expression
- Proceedings of the 2018 Santa Fe Bone Symposium: Advances in the Management of Osteoporosis
- The telomere world and aging: Analytical challenges and future perspectives
- The cross-talk between sphingolipids and insulin-like growth factor signaling: significance for aging and neurodegeneration
- Young Hematopoietic Stem Cells Ameliorate Age-Associated Phenotypes and Extend Lifespan in Mice
- MicroRNA networks modulate oxidative stress in cancer
- The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage
- Crosstalk between HGF and TGF-ß signaling pathways in adult liver progenitor cells and hepatocellular carcinoma cells
- The Evolving Role of CD8+ CD28− Immunosenescent T Cells in Cancer Immunology
- Astrocytes autophagy in aging and neurodegenerative disorders
- Stem cells: a path towards improved epilepsy therapies
- Novel function of PiT1/SLC20A1 in LPS-related inflammation and wound healing
- Biomarkers of Aging (With a Clinical Potential in Oncology)
- Mitochondrial oxidative stress-induced transcript variants of ATF3 mediate lipotoxic brain microvascular injury
- MOTOR BEHAVIOR
- Mediterranean Diet (Prong-4)
- Resveratrol: A New Potential Therapeutic Agent for Melanoma?
- EFFECT OF ADVANCED MATERNAL AGE ON PREGNANCY
