• SHOP
    • COMBOS
    • TESTIMONIALS
    • CART
    • INGREDIENTS
      • 2-Deoxy-D-Glucose (2DG)
      • Acacia Cyanophylla Flower
      • Acori Graminei Rhizoma
      • Aegle Marmelos Correa
      • Agaricus Blazei
      • Aged Garlic Extract
      • Aframomum Melegueta
      • Aloe Arborescens
      • Albizia
      • Alpinia Officinarum
      • Alternanthera Sessilis
      • American Ginseng
      • Amygdalin
      • Anacyclus Pyrethrum
      • Angelica Archangelica
      • Angelica Sinensis
      • Antrodia
      • Artichoke Leaf
      • Artocarpin
      • Ajuga Turkestanica
      • Ashwagandha
      • Aspalathin
      • Astragalus Complanatus
      • Avena Sativa
      • Bacopa Monnieri
      • Bavachin
      • Bee Pollen
      • Betulinic Acid
      • Boswellic Acid
      • Brevilin A
      • Campesterol
      • Casticin
      • Chrysin
      • Cinnamomum Zeylanicum
      • Citrullus Colocynthis
      • Citrus Reticulata Peel
      • Codonopsis
      • Costunolide
      • Cucurbitacin D
      • Daidzein
      • Decursin
      • Delphinidin
      • Digitalis Purprea (Digoxin)
      • Diosmin
      • Embelin
      • Gallic Acid
      • Glycitein
      • Glycyrrhizin
      • Hyperforin
      • Icariin
      • Isorhamnetin
      • Isoorientin
      • Isovitexin
      • Jaceosidin
      • Kaempferol
      • Kurarinone
      • Lemon balm
      • Licoricidin
      • Lipoic acid
      • Lupeol
      • Magnolol
      • Mulberry Leaf
      • Naringenin
      • Nobiletin
      • Oleacein
      • Oleanolic acid
      • Oridonin
      • Parthenolide
      • Phloroglucinol
      • Piceatannol
      • Pristimerin
      • Proanthocyanidins
      • Procyanidin B3
      • Pseudolaric acid b
      • Pterostilbene
      • Rutin
      • Solidago Virgaurea
      • Tangeretin
      • Taraxasterol
      • Trichostatin A
      • Wedelolactone
      • Wogonin
      • Yerba Mate
    • ABOUT
    • SCIENTIFIC STUDIES
      • ALLERGIES & CYTOKINES
      • ANTI-ACNE EFFECT OF FLAVONOIDS AND POLYPHENOLS
      • ADVANCED GLYCATION END PRODUCTS (AGES)
      • AMPK
      • ANTI-AGING EFFECTS OF FLAVONOIDS & POLYPHENOLS
      • ANTI-APOPTOTIC PATHWAYS
      • ANTI-CANCER EFFECTS OF FLAVONOIDS & POLYPHENOLS
      • ANTI-INFLAMMATORY EFFECTS OF FLAVONOIDS & POLYPHENOLS
      • ANTI-VIRAL EFFECTS OF FLAVONOIDS & POLYPHENOLS
      • APOPTOSIS
      • AUTOPHAGY
      • BCL-2
      • BCL-W
      • BCL-XL
      • BECLIN-1 & AUTOPHAGY
      • BH3 MIMETICS
      • BIM aka BCL2L11
      • BMI-1
      • CARDIAC GLYCOSIDES
      • CENTENARIANS
      • CYP2E1
      • CYTOKINES IN PAIN, INFLAMMATION & AGING
      • DAF-16
      • EPIGENETIC MODIFIERS
      • FGF21
      • KLOTHO
      • FASTING, CALORIE RESTRICTION & EXTENDING LIFESPAN
      • FOXO3
      • FOXO4
      • HMGB1
      • HSP90 INHIBITORS
      • HYPERINSULINEMIA
      • IKK
      • IL-6/STAT3
      • INFECTOBESITY
      • INFLAMMATION & ANXIETY
      • INFLAMMATION & CANCER
      • INFLAMMATION & DEPRESSION
      • INFLAMMATION & OBESITY
      • INFLAMMAGING
      • INSULIN & AGING
      • JAK INHIBITION ALLEVIATES SASP
      • JNK ACTIVATION PREVENTS PREMATURE SENESCENCE
      • KETONE BODIES
      • KETOGENIC DIET
      • LIFESPAN EXTENSION
      • MATRIX METALLOPROTEINASES (MMPs)
      • MCL-1
      • MDM2 INHIBITION AS SASP INHIBITOR
      • MSG (MONOSOSODIUM GLUTAMATE)
      • mTOR: THE RAPID AGING PATHWAY
      • NEUROINFLAMMATION
      • NMDA & ANXIETY & DEPRESSION
      • NOOTROPICS
      • NRF2: MASTER REGULATOR OF THE AGING PROCESS
      • NF-KB
      • ONCOGENE ACTIVATION INDUCED SENESCENCE
      • OXIDATIVE STRESS & AGING
      • P16INK4A
      • P38MAPK
      • P53: TUMOR SUPRESSOR
      • PPARY2
      • PREMATURE SENESCENCE
      • SASP & ADIPOSE TISSUE
      • SENESCENT CELLS, SASP & SENOLYTICS
      • SENESCENCE-BETA-GALACTOSIDASE (SA-β-gal or SABG)
      • SKIN PHOTOAGING (Preventing & Repairing)
      • SIRT1 & LONGEVITY
      • SUGAR & AGING
      • STAT3
      • TELOMERE SHORTENING & PREMATURE AGING
    • HOME
    • FAQ
    • CONTACT
    • INTERSTELLAR 88/8: EXTREME WEIGHTLOSS PROTOCOL
    • The Ultimate Dry Fasting Resource
    Icariin
    January 16, 2020
    Gossypol
    January 17, 2020
    1. Exercise prevents diet-induced cellular senescence in adipose tissue
    2. Physiological aging: links among adipose tissue dysfunction, diabetes, and frailty
    3. Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses
    4. Aging and adipose tissue: potential interventions for diabetes and regenerative medicine
    5. Roles of chemokine ligand-2 (CXCL2) and neutrophils in influencing endothelial cell function and inflammation of human adipose tissue
    6. Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities
    7. The emerging role of senescent cells in tissue homeostasis and pathophysiology
    8. Cellular senescence and the senescent secretory phenotype in age-related chronic diseases
    9. JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
    10. Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice
    11. Aging-related inflammation in osteoarthritis
    12. Cellular senescence in type 2 diabetes: a therapeutic opportunity
    13. The fat cell senescence hypothesis: a mechanism responsible for abrogating the resolution of inflammation in chronic disease
    14. Feast and famine: adipose tissue adaptations for healthy aging
    15. Macrophages in age-related chronic inflammatory diseases
    16. Proposed metabolic vicious circle in patients with large myocardial infarcts and high plasma-free-fatty-acid concentrations
    17. Perspective: targeting the JAK/STAT pathway to fight age-related dysfunction
    18. Effect of low-dose rapamycin on senescence markers and physical functioning in older adults with coronary artery disease: results of a pilot study.
    19. Systemic DNA damage response and metabolic syndrome as a premalignant state
    20. Stem cell senescence and regenerative paradigms
    21. Cellular senescence in ageing, age-related disease and longevity
    22. Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus
    23. Phytochemicals suppress nuclear factor-κB signaling: impact on health span and the aging process
    24. Effect of lipopolysaccharides on adipogenic potential and premature senescence of adipocyte progenitors
    25. Developments in our understanding of the effects of growth hormone on white adipose tissue from mice: implications to the clinic
    26. Cellular senescence in aging and age-related disease: from mechanisms to therapy
    27. Deleted in B reast C ancer 1 regulates cellular senescence during obesity
    28. Growth differentiation factor 6 derived from mesenchymal stem/stromal cells reduces age-related functional deterioration in multiple tissues
    29. Mitochondrial dysfunction induces senescence with a distinct secretory phenotype
    30. Impact of growth hormone on regulation of adipose tissue
    31. Senescence-associated secretory phenotype (SASP) involvement in the development of cancer, aging, and age related diseases
    32. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
    33. Curcumin, inflammation, ageing and age-related diseases
    34. Inflammation, ageing and chronic disease
    35. Geroscience: linking aging to chronic disease
    36. Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)
    37. Mitochondrial dysfunction meets senescence
    38. Finding Shangri-La: limiting the impact of senescence on aging
    39. Inflamm-ageing
    40. Characterization of senescence of culture-expanded human adipose-derived mesenchymal stem cells
    41. An experiment to determine the active therapeutic moiety of sulphasalazine
    42. Aging of the human innate immune system in HIV infection
    43. Metabolic syndrome is a real disease and premalignant state induced by oncogenic stresses to block malignant transformation
    44. Mechanisms and metabolic implications of regional differences among fat depots
    45. The role of inflammation in age-related disease
    46. “Inflammaging” as a druggable target: a senescence-associated secretory phenotype—centered view of type 2 diabetes
    47. Antagonizing Effects of Aspartic Acid against Ultraviolet A-Induced Downregulation of the Stemness of Human adipose tissue-Derived Mesenchymal Stem …
    48. Cellular senescence: from physiology to pathology
    49. RETRACTED: Chronic Inflammation: Accelerator of Biological Aging
    50. Senescence associated macrophages and “macroph-aging”: are they pieces of the same puzzle?
    51. Cellular senescence and the biology of aging, disease, and frailty
    52. Targeting senescent cells enhances adipogenesis and metabolic function in old age
    53. Urinary Iodine Concentrations in Mothers and their Term Newborns
    54. Aging and osteoarthritis
    55. Obesity-associated mechanisms of hepatocarcinogenesis
    56. P12 Pathological vascular smooth muscle cells remodelling in murine models of abdominal aortic aneurysm
    57. The aging adipose organ: lipid redistribution, inflammation, and cellular senescence
    58. Ginsenoside Rd attenuates the inflammatory response via modulating p38 and JNK signaling pathways in rats with TNBS-induced relapsing colitis
    59. Impact of cellular senescence signature on ageing research
    60. Metabolic and microenvironment changes in the mammary of calorie restricted, normal weight, and obese mice throughout the lifespan
    61. Senescent cells: a novel therapeutic target for aging and age‐related diseases
    62. … and Metabolic Dysfunction during Aging and Senescence: Effect of lipopolysaccharides on adipogenic potential and premature senescence of adipocyte …
    63. Crossing Boundaries to Propel Tissue Engineering into the Clinic
    64. Mitochondrial damage induces senescence with a twisted arm
    65. Therapeutic effect and mechanism of proanthocyanidins from grape seeds in rats with TNBS-induced ulcerative colitis
    66. Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases
    67. Pathogenesis of hepatocellular carcinoma development in non-alcoholic fatty liver disease
    68. ÔØ Å ÒÙ× Ö ÔØ
    69. Aging of the immune system: focus on inflammation and vaccination
    70. Molecular mechanisms of ageing and related diseases
    71. Senescent cells: SASPected drivers of age-related pathologies
    72. Control of p53 and NF-κB signaling by WIP1 and MIF: role in cellular senescence and organismal aging
    73. p21 both attenuates and drives senescence and aging in BubR1 progeroid mice
    74. Stop feeding cancer: pro-inflammatory role of visceral adiposity in liver cancer
    75. Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
    76. Metabolic control of longevity
    77. Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells
    78. Microbiome–Obesity–Liver Cancer Interaction: Senescence of Hepatic Stellate Cells and Bile Acids Play New Roles
    79. Ameliorative effects of 3, 4-oxo-isopropylidene-shikimic acid on experimental colitis and their mechanisms in rats
    80. Hepatocellular carcinoma and lifestyles
    81. Inflammation and cellular senescence: potential contribution to chronic diseases and disabilities with aging
    82. Toll like receptor signaling in “inflammaging”: microRNA as new players
    83. Depleting senescent cells to combat aging
    84. www. aging-us. com AGING 2016, Vol. 8, Advance
    85. High-throughput screening reveals enzyme and GPCR targets as putative binding sites for d-deprenyl
    86. Adipocytes and neutrophils give a helping hand to pancreatic cancers
    87. Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice
    88. Anti-inflammatory effects of Pulvis Fellis Suis extract in mice with ulcerative colitis
    89. Ageing and the pathogenesis of osteoarthritis
    90. Aging of mice is associated with p16 (Ink4a)-and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells
    91. Cellular senescence in aging and osteoarthritis: implications for cartilage repair
    92. Oxidative stress and the ageing endocrine system
    93. Clinical strategies and animal models for developing senolytic agents
    94. Liver cancer: connections with obesity, fatty liver, and cirrhosis
    95. Of flies, mice, and men: evolutionarily conserved tissue damage responses and aging
    96. Age-dependent dysregulation of innate immunity
    97. Endothelial progenitor cells: from senescence to rejuvenation
    98. Aging: a common driver of chronic diseases and a target for novel interventions
    99. Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells’ homeostasis
    100. Extracellular microRNAs and endothelial hyperglycaemic memory: a therapeutic opportunity?
    101. The role of oxidative stress and inflammation in cardiovascular aging
    102. Cell autonomous and non-autonomous effects of senescent cells in the skin
    103. A case of rheumatoid arthritis exhibiting accelerating rheumatoid pleurisy during low-dose weekly methotrexate therapy
    104. Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer
    105. The role of senescent cells in ageing
    106. Sowing the seeds of cancer: telomeres and age-associated tumorigenesis
    107. Tim-3: an emerging target in the cancer immunotherapy landscape
    108. Effect of traditional Chinese medicinal enemas on ulcerative colitis of rats
    109. Diabetes and cancer, common threads and missing links
    110. Hepatocellular carcinoma in nonalcoholic fatty liver: role of environmental and genetic factors
    111. Translational research in immune senescence: assessing the relevance of current models
    112. Elimination of p19ARF-expressing cells enhances pulmonary function in mice
    113. The effects of aging on the development of osteoarthritis
    114. Cellular senescence impact on immune cell fate and function
    115. Effects of proanthocyanidins from grape seed on treatment of recurrent ulcerative colitis in rats
    116. Proanthocyanidins from grape seeds modulate the NF-κB signal transduction pathways in rats with TNBS-induced ulcerative colitis
    117. Morphological, molecular and functional differences of adult bone marrow-and adipose-derived stem cells isolated from rats of different ages
    118. The role of insulin resistance in nonalcoholic steatohepatitis and liver disease development–a potential therapeutic target?
    119. Nonalcoholic fatty liver disease: pathogenesis and disease spectrum
    120. The possible mechanisms of Picrasma quassiodes (D. Don) Benn. in the treatment of colitis induced by 2, 4, 6-trinitrobenzene sulfonic acid in mice
    121. Aldosterone induces p21‐regulated apoptosis via increased synthesis and secretion of tumour necrosis factor‐α in human proximal tubular cells
    122. Senescence as a general cellular response to stress: a mini-review
    123. Obesity and liver cancer
    124. Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model
    125. Reversing multiple age-related pathologies by controlling the senescence-associated secretory phenotype of stem cells
    126. Histone macroH2A1. 2 promotes metabolic health and leanness by inhibiting adipogenesis
    127. Pivotal role of Sirt6 in the crosstalk among ageing, metabolic syndrome and osteoarthritis
    128. Proanthocyanidins from grape seeds modulates the nuclear factor-kappa B signal transduction pathways in rats with TNBS-induced recurrent ulcerative colitis
    129. Maternal obesity programs senescence signaling and glucose metabolism in osteo-progenitors from rat and human
    130. Immunosurveillance of senescent cells: the bright side of the senescence program
    131. Obesity and the gut microbiome: pathophysiological aspects
    132. Ageing induced vascular smooth muscle cell senescence in atherosclerosis
    133. Cancer and inflammation: an old intuition with rapidly evolving new concepts
    134. Obesity and cancer pathogenesis
    135. Metabolic consequences of HIV: pathogenic insights
    136. Noncoding RNA control of cellular senescence
    137. Protective effects of 3, 4-oxo-isopropylidene-shikimic acid on experimental colitis induced by trinitrobenzenesulfonic acid in rats
    138. Inflammaging decreases adaptive and innate immune responses in mice and humans
    139. Senescence and the pro-tumorigenic stroma
    140. Siegesbeckia pubescens ameliorates experimental ulcerative colitis in rats by modulating PPARγ.
    141. Therapeutic effect of ginsenoside Rd in rats with TNBS-induced recurrent ulcerative colitis
    142. Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors
    143. Serum n3 polyunsaturated fatty acids are depleted in Crohn’s disease
    144. The cell secretome, a mediator of cell-to-cell communication
    145. Targeting senescent cells: possible implications for delaying skin aging: a mini-review
    146. DNA damage and innate immunity: links and trade-offs
    147. The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
    148. Protective effect of taurohyodeoxycholic acid from Pulvis Fellis Suis on trinitrobenzene sulfonic acid induced ulcerative colitis in mice
    149. Chronic inflammation, immune escape, and oncogenesis in the liver: a unique neighborhood for novel intersections
    150. Mesenchymal stem cells in regenerative medicine: focus on articular cartilage and intervertebral disc regeneration
    151. Interventions to slow aging in humans: are we ready?
    152. Anti-inflammatory activity and mechanisms of a lipid extract from hard-shelled mussel (Mytilus coruscus) in mice with dextran sulphate sodium-induced colitis
    153. DNA damage response and autophagy: a meaningful partnership
    154. NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies
    155. mTOR signaling from cellular senescence to organismal aging
    156. Erdheim–Chester disease: from palliative care to targeted treatment
    157. Gerosuppressant metformin: less is more
    158. Chemoprevention of obesity-related liver carcinogenesis by using pharmaceutical and nutraceutical agents
    159. Workshop report Key data from the 11th International Workshop on Adverse Drug Reactions and Co-Morbidities in HIV
    160. Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy
    161. Immune aging, dysmetabolism, and inflammation in neurological diseases
    162. Anti-inflammatory effects of Huangqin tang extract in mice on ulcerative colitis
    163. Conditioned media from human umbilical cord blood-derived mesenchymal stem cells inhibits melanogenesis by promoting proteasomal degradation of MITF
    164. Speeding up the clock: The past, present and future of progeria
    165. Mathematical integration of protein metabolism in growing lambs
    166. Short telomeres in key tissues initiate local and systemic aging in zebrafish
    167. Modelling age-related metabolic disorders in the mouse
    168. Disease drivers of aging
    169. Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their anti-tumor activity
    170. Diabetes and aging
    171. Exercise attenuates the major hallmarks of aging
    172. Long noncoding RNAs in diseases of aging
    173. Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation
    174. From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes
    175. Persistent DNA damage‐induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells
    176. Halofuginone reduces the inflammatory responses of DSS-induced colitis through metabolic reprogramming
    177. Obesity and cancer
    178. Senescence in human mesenchymal stem cells: functional changes and implications in stem cell-based therapy
    179. Bile acids and the gut microbiome
    180. Aging, clonality, and rejuvenation of hematopoietic stem cells
    181. Dysregulated inflammation as a risk factor for pneumonia in the elderly
    182. Ageing and the telomere connection: An intimate relationship with inflammation
    183. The study of skeletal aging is coming of age: A forum on aging and skeletal health
    184. Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of INS-1 …
    185. Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression
    186. Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
    187. SYSTEMIC DNA DAMAGE RESPONSE AND METABOLIC SYNDROME
    188. Secreted microvesicular miR‐31 inhibits osteogenic differentiation of mesenchymal stem cells
    189. Are there roles for brain cell senescence in aging and neurodegenerative disorders?
    190. Effect of Manuka honey and sulfasalazine in combination to promote antioxidant defense system in experimentally induced ulcerative colitis model in rats
    191. Effect of hyperglycemia on hepatocellular carcinoma development in diabetes
    192. NF-κB in aging and disease
    193. Toward the comprehensive understanding of the gut ecosystem via metabolomics-based integrated omics approach
    194. Interleukin‐8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor‐α and interleukin‐1β
    195. Energetic interventions for healthspan and resiliency with aging
    196. Secretome of human fetal mesenchymal stem cell ameliorates replicative senescence
    197. Caloric restriction and aging stem cells: the stick and the carrot?
    198. Exercise enhances wound healing and prevents cancer progression during aging by targeting macrophage polarity
    199. The promise of slow down ageing may come from curcumin
    200. Effects of mimic of manganese superoxide dismutase on 2, 4, 6-trinitrobenzene sulfonic acid-induced colitis in rats
    201. Genome-wide chromatin state transitions associated with developmental and environmental cues
    202. Oxidative stress, cellular senescence and ageing
    203. 7 Immune Senescence
    204. What Is Homeostasis?
    205. Atypical pyoderma gangrenosum with leukemia
    206. INVESTIGATING MOLECULAR PATHWAYS OF ROS-INDUCED PRO-INFLAMMATORY SENESCENCE IN PREADIPOCYTES
    207. Vascular wall-resident multipotent stem cells of mesenchymal nature within the process of vascular remodeling: cellular basis, clinical relevance, and …
    208. Recombinant HSP70 and mild heat shock stimulate growth of aged mesenchymal stem cells
    209. Senescence in chronic obstructive pulmonary disease
    210. Fibrogenesis and carcinogenesis in nonalcoholic steatohepatitis (NASH): involvement of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase …
    211. Non-alcoholic steatohepatitis and hepatocellular carcinoma: implications for lycopene intervention
    212. Telomeres and age-related disease: how telomere biology informs clinical paradigms
    213. Characterization of the human salivary proteome by capillary isoelectric focusing/nanoreversed-phase liquid chromatography coupled with ESI-tandem MS
    214. Macromolecular degradation systems and cardiovascular aging
    215. Acute phase serum amyloid A induces proinflammatory cytokines and mineralization via toll-like receptor 4 in mesenchymal stem cells
    216. Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
    217. Understanding The Regulation Of Adipogenesis And Adipocyte Metabolism In Obesity
    218. Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture
    219. The senescence arrest program and the cell cycle
    220. The posttranslational processing of prelamin A and disease
    221. Caveolae and signalling in cancer
    222. Therapy with multipotent mesenchymal stromal cells protects lungs from radiation-induced injury and reduces the risk of lung metastasis
    223. Frailty and sarcopenia as the basis for the phenotypic manifestation of chronic diseases in older adults
    224. From experimental design to functional gene networks: DNA microarray contribution to skin ageing research
    225. Senescence-associated MCP-1 secretion is dependent on a decline in BMI1 in human mesenchymal stromal cells
    226. Tumour biology of obesity-related cancers: understanding the molecular concept for better diagnosis and treatment
    227. Protective effect of sanguinarine against acetic acid-induced ulcerative colitis in mice
    228. Living Large: What Mouse Models Reveal about Growth Hormone and Obesity
    229. Signaling networks determining life span
    230. Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity
    231. The second international conference “genetics of aging and longevity”
    232. Amniotic epithelial cells: a new tool to combat aging and age-related diseases?
    233. Mesenchymal stem cells in wound repair, tissue homeostasis, and aging
    234. The role and regulation of the nuclear factor kappa B signalling pathway in human labour
    235. Physiological regulation of the heat shock response by glutamine: implications for chronic low-grade inflammatory diseases in age-related conditions
    236. At the stem of youth and health
    237. New Insights into the Management and Therapeutics of Type 2 Diabetes
    238. Epigallocatechin-3-gallate ameliorates rats colitis induced by acetic acid
    239. Cellular and molecular biology of aging endothelial cells
    240. The nuclear lamina in health and disease
    241. The Biology of Aging: Role in Cancer, Metabolic Dysfunction, and Health Disparities
    242. Cellular and molecular basis of the imbalance between vascular damage and repair in ageing and age-related diseases: as biomarkers and targets for new …
    243. Interrater reliability of a clinical scale to assess knee joint effusion
    244. Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence?
    245. Cell cycle arrest and the evolution of chronic kidney disease from acute kidney injury
    246. Biomarkers and Inflammatory Network in Aging: Targets for Therapies
    247. Implications of multipotent mesenchymal stromal cell aging
    248. Connecting the dots: from DNA damage and repair to aging
    249. Metformin‐mediated increase in DICER1 regulates microRNA expression and cellular senescence
    250. MicroRNA-34a induces endothelial progenitor cell senescence and impedes its angiogenesis via suppressing silent information regulator 1
    251. Identification of senescent cells in the bone microenvironment
    252. Identification of microRNAs dysregulated in cellular senescence driven by endogenous genotoxic stress
    253. Melatonin and the theories of aging: a critical appraisal of melatonin’s role in antiaging mechanisms
    254. Increasing longevity through caloric restriction or rapamycin feeding in mammals: common mechanisms for common outcomes?
    255. Extracellular microRNAs and endothelial hyperglycemic memory: a therapeutic opportunity?
    256. Skin mirrors human aging
    257. miR‐335 correlates with senescence/aging in human mesenchymal stem cells and inhibits their therapeutic actions through inhibition of AP‐1 activity
    258. Effect of different doses of Manuka honey in experimentally induced inflammatory bowel disease in rats
    259. Illuminating inflammasome activity in vivo
    260. Metabolic exchanges within tumor microenvironment
    261. Inflammation and atherosclerosis in rheumatoid arthritis
    262. From cellular senescence to age-associated diseases: the miRNA connection
    263. Melatonin reduces endoplasmic reticulum stress and autophagy in liver of leptin‐deficient mice
    264. Modulation of Membrane Transport Systems
    265. The role of chromatin reorganization in the process of cellular senescence
    266. Pleiotropic effects of tocotrienols and quercetin on cellular senescence: introducing the perspective of senolytic effects of phytochemicals
    267. Role of DNA damage in cardiovascular disease
    268. The telomere syndromes
    269. Somatic stem cell aging and malignant transformation–impact on therapeutic application
    270. Organelle Stress and mTOR in Aging-Associated Inflammation
    271. ACC 284
    272. Regulatory roles of miRNAs in aging
    273. Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells
    274. Mechanisms of metastatic tumor dormancy
    275. Liposarcoma
    276. Liposarcomas-proliferation, senescence and the role of DDIT3
    277. Senescence bypass in mesenchymal stem cells: a potential pathogenesis and implications of pro-senescence therapy in sarcomas
    278. Mechanisms of resveratrol-induced inhibition of clonal expansion and terminal adipogenic differentiation in 3T3-L1 preadipocytes
    279. Progressive loss of SIRT1 with cell cycle withdrawal
    280. Targeting Senescent Cells to Improve Human Health
    281. Defining mesenchymal stromal cells responsiveness to IFNγ as a surrogate measure of suppressive potency
    282. The germline/soma dichotomy: implications for aging and degenerative disease
    283. Identifying of the causative genes in spontaneous mutant mouse strains by forward-reverse genetics
    284. Phenylbutyric Acid: simple structure-multiple effects
    285. The role of immunosenescence in the development of age-related diseases
    286. Melatonin reverses H2O2‐induced premature senescence in mesenchymal stem cells via the SIRT1‐dependent pathway
    287. Recent advances in mouse models of obesity-and nonalcoholic steatohepatitis-associated hepatocarcinogenesis
    288. Cellular senescence and vascular disease: novel routes to better understanding and therapy
    289. Telomeres, NAFLD and chronic liver disease
    290. The emergence of geromirs: A group of micrornas implicated in aging
    291. The Role of Stem Cell Genomic Instability in Aging
    292. Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic …
    293. Regulation of senescence by microRNA biogenesis factors
    294. Host resistance and immune aging
    295. Coming of age: molecular drivers of aging and therapeutic opportunities
    296. ISSN 0975-413X CODEN (USA): PCHHAX
    297. Finding Ponce de Leon’s Pill: challenges in screening for anti-aging molecules
    298. Thymic involution perturbs negative selection leading to autoreactive T cells that induce chronic inflammation
    299. An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer
    300. Growth hormone is a cellular senescence target in pituitary and nonpituitary cells
    301. MicroRNAs linking inflamm-aging, cellular senescence and cancer
    302. Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial …
    303. Medial arterial calcification: an overlooked player in peripheral arterial disease
    304. Lessons from Hepatocyte-Specific Cyp51 Knockout Mice: Impaired Cholesterol Synthesis Leads to Oval Cell-Driven Liver Injury
    305. Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy
    306. Inflammasomes: guardians of cytosolic sanctity
    307. As we age: Does slippage of quality control in the immune system lead to collateral damage?
    308. Anti-aging pharmacology: promises and pitfalls
    309. Neovascularization capacity of mesenchymal stromal cells from critical limb ischemia patients is equivalent to healthy controls
    310. Effect of hyperglycemia on hepatocellular carcinoma development in diabetes
    311. Expression of HOXD9 in fibroblast-like synoviocytes from rheumatoid arthritis patients
    312. The Disrupted Steady-State: Tipping the Balance in Favour of Cancer
    313. The Way Forward: Translation
    314. Intervention of aging and its effects on cellular health
    315. DNA damage response and immune defense: links and mechanisms
    316. Towards an evidence-based model of aging
    317. iPSCs as a major opportunity to understand and cure age-related diseases
    318. The biology of aging: 1985–2010 and beyond
    319. DNA damage: from chronic inflammation to age-related deterioration
    320. The emerging role of Notch pathway in ageing: focus on the related mechanisms in age-related diseases
    321. SPEAKER ABSTRACTS
    322. miR-29c-3p promotes senescence of human mesenchymal stem cells by targeting CNOT6 through p53–p21 and p16–pRB pathways
    323. Osteopontin, a key mediator expressed by senescent pulmonary vascular cells in pulmonary hypertension
    324. NF-κB signaling as a driver of ageing
    325. The Cellular Senescence Program
    326. Age-related changes in blood-brain barrier integrity in C57BL/6J mice
    327. Ultrastructural analysis of changes in neurons of the mouse internal anal sphincter during ageing
    328. Age-related changes to lumbosacral spinal cord motoneurons that modulate bladder and bowel functions in male C57BL/6 mice
    329. The metabolic regulation of cellular ageing
    330. The inflammatory network: bridging senescent stroma and epithelial tumorigenesis
    331. Cellular senescence and inflammation in aging and age-related disease
    332. Influence of aging on the quantity and quality of human cardiac stem cells
    333. Prospects and challenges for the use of stem cell technologies to develop novel therapies for Parkinson disease
    334. Hypoxia-inducible histone lysine demethylases: impact on the aging process and age-related diseases
    335. Autophagy and cancer metabolism
    336. Assessing cell and organ senescence biomarkers
    337. Sphingolipids in inflammation: pathological implications and potential therapeutic targets
    338. ÔØ Å ÒÙ× Ö ÔØ
    339. Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer
    340. Cellular senescence in cardiovascular diseases: potential age-related mechanisms and implications for treatment
    341. Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells
    342. Pathogenesis of osteoarthritis
    343. Better living through chemistry: caloric restriction (CR) and CR mimetics alter genome function to promote increased health and lifespan
    344. Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence
    345. Intestinal anti-inflammatory effect of the rhizome extracts of Menispermum dauricum DC. on trinitrobenzene sulfonic acid induced ulcerative colitis in mice
    346. Biosprays: From the biomedical to the clinical sciences
    347. Influence of age and physical fitness on miRna-21, TGF-ß and its receptors in leukocytes of healthy women.
    348. Caspase inhibition switches doxorubicin-induced apoptosis to senescence
    349. MicroRNAs as mediators of the ageing process
    350. Modelling ageing and age-related disease
    351. PROTECTIVE EFFECT OF RICE BRAN WATER EXTRACT ON PANCREAS OF RATS FED A HIGH-FAT DIET
    352. New objective findings after whiplash injuries: high blood flow in painful cervical soft tissue: an ultrasound pilot study
    353. Genome integrity in aging: human syndromes, mouse models, and therapeutic options
    354. Conditioned medium derived from rat amniotic epithelial cells confers protection against inflammation, cancer, and senescence
    355. Endothelial cell senescence and thrombosis: ageing clots
    356. A Fungal Glycosphingolipid Directly Activates Natural Killer T Cells and Rapidly Induces Airways Disease
    357. NAFLD and hepatocellular Carcinoma: how big a problem is this really?
    358. Mast cells and histamine are triggering the NF-κB-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammation
    359. Oral submucous fibrosis: Review on mechanisms of pathogenesis and malignant transformation
    360. Extracellular vesicles in lung microenvironment and pathogenesis
    361. Vascular endothelial senescence: from mechanisms to pathophysiology
    362. Autoimmune atherosclerosis in 3D: how it develops, how to diagnose and what to do
    363. Physiological roles of the DNA demethylation-associated proteins Gadd45a and Ing1
    364. Stress-induced premature senescence of endothelial and endothelial progenitor cells
    365. Regulation of Senescence by microRNAs
    366. Muscle stem cell aging: regulation and rejuvenation
    367. kk journal of experimental biology.
    368. 2.20 Behcet’s disease and miscellaneous rheumatic conditions
    369. Inflammatory bowel disease part I: ulcerative colitis–pathophysiology and conventional and alternative treatment options
    370. The Buck Institute: An inside look
    371. Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells
    372. Orphan technology: Unfunded early-stage bioscience is dropped off at the firehouse
    373. Computational approaches for the transcriptomics, proteomics and epigenetic analysis in adult stem cells
    374. The secret lives of stem cells: Unraveling the molecular basis of stem cell aging
    375. Positive and negative effects of cellular senescence during female reproductive aging and pregnancy
    376. Global profiling and relative quantifiction of histones, histone PTMs and histone-modifying enzymes in mesenchymal stem cells using LC-MS/MS and a novel …
    377. The 10th World Congress on Inflammation
    378. Ms. No.: METHODS-D-15-00125 R1–Revised Version
    379. Are aging biomarkers clinically relevant in oncogeriatrics?
    380. Apocrine secretion: new insights into an old phenomenon
    381. Molecular links between cellular senescence, longevity and age-related diseases–a systems biology perspective
    382. Practical Laboratory Medicine
    383. Stop Aging Disease! ICAD 2014.
    384. PROGRESS REPORT ON THE ROLE OF MITOCHONDRIAL ISOCITRATE DEHYDROGENASE 2 IN AGE-RELATED HEARING LOSS IN MICE
    385. Impact of physical activity on immune function and inflammation in the elderly
    386. Four faces of cellular senescence
    387. Interventions to slow aging in humans: Are we ready?
    388. Determination of serum visfatin level in patients with Behcet disease, comparing with normal population
    389. Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration
    390. DNA damage: a main determinant of vascular aging
    391. The Role of Estrogen Deficiency in Skin Aging and Wound Healing
    392. Comparative analysis of gene expression data reveals novel targets of senescence-associated microRNAs
    393. Accelerated telomere shortening in acromegaly; IGF-I induces telomere shortening and cellular senescence
    394. Salvianolic acid B restored impaired barrier function via downregulation of MLCK by microRNA-1 in rat colitis model
    395. IL-6 and related cytokines as the critical lynchpins between inflammation and cancer
    396. Anti-stress gene response in cell and tissue ageing: role of transcription factor NF-E2-related factor-2 and effect of dietary activators
    397. Protective Effect of Paronychia argentea L. on Acetic Acid Induced Ulcerative Colitis in Mice by Regulating Antioxidant Parameters and Inflammatory Markers
    398. 7th Joint Meeting of the European Tissue Repair Society (ETRS) with the Wound Healing Society
    399. Human Amniotic Fluid Mesenchymal Stromal cells (AF-MSCs) are Less Prone to in vitro Senescence Process Compared with Bone Marrow MSCs
    400. The central role of muscle stem cells in regenerative failure with aging
    401. Modulation of ageing characteristics with an anti-ageing compound
    402. Insulin pathway and its correlation with ageing and longevity
    403. Glucocorticoids suppress selected components of the senescence‐associated secretory phenotype
    404. Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy
    405. Stem cells and cancer stem cells
    406. Nutritional Modulators of Cellular Senescence In Vitro
    407. Non‐cell autonomous or secretory tumor suppression
    408. The Aging Superorganism
    409. Systemic problems: a perspective on stem cell aging and rejuvenation
    410. Modulators of cellular senescence: mechanisms, promises, and challenges from in vitro studies with dietary bioactive compounds
    411. Pharmacotherapeutics ECG of the Month
    412. Molecular Mechanisms of Lycopene Actions on Liver Disease Outcomes
    413. Pathophysiological fundamentals of diabetic cardiomyopathy
    414. The gut microbial endocrine organ: bacterially derived signals driving cardiometabolic diseases
    415. The role of miRNAs in common inflammatory arthropathies: osteoarthritis and gouty arthritis
    416. Similarities in gene expression profiles during in vitro aging of primary human embryonic lung and foreskin fibroblasts
    417. Rescuing the regenerative capacity of human mesenchymal stem cells from the elderly
    418. Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
    419. Nuclear lamina defects cause ATM-dependent NF
    420. Interventions for age-related diseases: Shifting the paradigm
    421. An Arf-Egr-C
    422. Biomolecular bases of the senescence process and cancer. A new approach to oncological treatment linked to ageing
    423. Aging, Immunosenescence, and Cancer
    424. A causal role of ATM-and NEMO-dependent NF-κB activation in DNA damage-induced senescence and aging
    425. Effect of bisphenol A on stress-induced premature senescence
    426. Progerin Expression Disrupts Critical Adult Stem Cell Functions that Mediate Tissue Repair Primarily through a Mechanism that Permanently Farnesylates Lamin A
    427. Systemic DNA damage responses in aging and diseases
    428. Osteoarthritis in the Elderly
    429. MDM2 levels modulate the cellular senescence response to CDK4 inhibition
    430. Functional-structural plant modeling
    431. Placental origins of chronic disease
    432. Inflammatory dysregulation and cancer: From molecular mechanisms to therapeutic opportunities
    433. The Role of Integrated Omics in Elucidating the Gut Microbiota Health Potentials
    434. Allogeneic mesenchymal stem cells transplantation in patients with refractory RA
    435. Stress-Induced Senescence: Molecular Pathways
    436. Neovascularization capacity of mesenchymal stromal cells from critical limb ischemia patients is equivalent to healthy controls
    437. Twist proteins as oxidative and hypoxic stress regulators
    438. The gut microbiota and the liver: implications for clinical practice
    439. The Epigenome and Aging
    440. Protein expression analysis of rat testes induced testicular toxicity with several reproductive toxicants
    441. Glenn Workshop on the Biology of Aging and AFAR Grantee Conference| JOINT MEETING
    442. The hallmarks of fibroblast ageing
    443. Signaling Networks Controlling Cellular Senescence
    444. Evidences of Early Senescence in Multiple Myeloma Bone Marrow
    445. Systemic administration of WY-14643, a selective synthetic agonist of peroxisome proliferator activator receptor-alpha, alters spinal neuronal firing in a rodent model of …
    446. Development of a mouse model for Hutchinson-Gilford progeria syndrome reveal defects in adult stem cell maintenance
    447. A potential role for miR-31 in osteoblastic transition of vascular smooth muscle cells and cortisol-induced osteoporosis
    448. Senescent mesenchymal stem cells promote colorectal cancer cells growth via galectin-3 expression
    449. BLT2 Protects Skin from the Damage Caused by Type 2 Diabetes Hyperglycemia by Increasing NO Production Through the nNOS Expression
    450. Molecular mechanisms of aging in MTDNA mutator mice
    451. Reversing stem cell aging: Implications for vascular regeneration
    452. Targeting the tumor stroma as a novel therapeutic approach for prostate cancer
    453. The Role of Macrophage Migration Inhibitory Factor in Osteoarthritis
    454. Evidence supporting the utility of blood cell respiratory capacity as a systemic marker of mitochondrial health and biological age
    455. Circadian molecular clock in lung pathophysiology
    456. Stop Aging Disease! ICAD 2014
    457. Investigating the differential instructive roles of WT1’s isoforms
    458. Osteoporosis and mechanisms of skeletal aging
    459. Functional Enrichment Analysis
    460. mberHappily (n) ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence
    461. Skin disease in laminopathy-associated premature aging
    462. Cellular and Molecular Mechanisms of Chronic Inflammation in Aging of Skeletal Muscle
    463. Oxidative stress-induced JNK activation contributes to proinflammatory phenotype of aging diabetic mesangial cells
    464. Histone methylation and aging: lessons learned from model systems
    465. Regulation of Phospholipase Isozymes by Nuclear Factor-κB in Human Gestational Tissues in Vitro
    466. Fluorescence Spectroscopy
    467. Psoriasis and inflammatory bowel disease: links and risks
    468. Prelamin A accelerates vascular calcification via activation of the DNA damage response and senescence-associated secretory phenotype in vascular smooth muscle …
    469. SIRT1 in endothelial cells as a novel target for the prevention of early vascular aging
    470. Cellular senescence as the causal nexus of aging
    471. MicroRNAs Regulate p21Waf1/Cip1 Protein Expression and the DNA Damage Response in Human Embryonic Stem Cells
    472. Basic Research
    473. Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective
    474. Relationships Among Body Mass Index, Nutrition, Internalizing Symptoms, and Ethnic Identity of Cherokee Youth Attending a Private American Indian Secondary …
    475. The role of the stress response gene Gadd45b in senescence
    476. False discovery rate (FDR)
    477. FBA Analysis, Plant-Pathogen Interactions
    478. Influence of aging on proliferation, pluripotency, immunogenic profiles from bone marrow mesenchymal stem cells
    479. Macrophage migration inhibitory factor regulates AKT signaling in hypoxic culture to modulate senescence of human mesenchymal stem cells
    480. Cell and molecular aging
    481. Loss of HuR leads to senescence-like cytokine induction in rodent fibroblasts by activating NF-κB
    482. Role of the nuclear envelope in regulation of ageing
    483. Chemotherapy-and Radiation-Induced Accelerated Senescence: Implications for Treatment Response, Tumor Progression and Cancer Survivorship
    484. Selenium and Senescence: Centering on Genome Maintenance
    485. Author statement
    486. Mechanisms of action of anti-TNF-α antibodies in inflammatory bowel disease
    487. Immortality: Myth or becoming Reality
    488. Skin, Mucosa and Menopause
    489. SUPPLEMENTARY TABLES
    490. Proteome analysis of formalin-fixed and paraffin-embedded tissue
    491. Framework Region (FR-IMGT)
    492. Frequent Pattern Mining
    493. Founders Effect
    494. Fisher’s Test
    495. Frequency
    496. Frequentist Approach
    497. Fitness
    498. Forward-scattered Light (FSC)
    499. Fluorescent Markers
    500. Fluorescence Microscopy
    501. Functional/Signature Network Module for Target Pathway/Gene Discovery
    502. Forward and Inverse Parameter Estimation for Metabolic Models
    503. Feature Selection
    504. Fitness Function
    505. Feedback Regulation
    506. Fibroblasts
    507. Feasibility
    508. Functional Modules and Complexes
    509. FunctionalityType
    510. Flux Balance Analysis
    511. Fokker–Planck Equation
    512. Faceted Browsing
    513. Fluorescence-activated Cell Sorting
    514. Flow Cytometry
    515. Frame Language
    516. Function, biological
    517. Feed Forward Loop
    518. Fluorophore
    519. Fluorescence Microscope
    520. False Positive Rate
    521. Fuzzy Logic
    522. Functional
    523. Flux Control Coefficient
    524. Fluorescence
    525. Functor
    526. Fourier Transform Infrared Microspectroscopy (FTIR)
    527. FuGE
    528. Foundational Model of Anatomy
    529. Floquet Multiplier
    530. Function, Distributed
    531. 9.1 Gut Microbiota
    532. Ageing and inflammation with focus on end-stage renal diseases: genetic and epigenetic factors
    533. The pleiotropic effects of HMG-CoA reductase inhibitors in inflammatory arthritis
    534. Assessing Pain and Inflammation in Arthritis Using Novel Imaging Methods
    535. The skin as a mirror of the aging process
    536. Hyperalgesia and allodynia to superficial and deep-tissue mechanical stimulation within and outside of the UVB irradiated area in human skin
    537. IL-6 secreted from senescent mesenchymal stem cells promotes proliferation and migration of breast cancer cells
    538. The role of telomere damage in cardiomyocyte ageing
    539. Gut Microbiota and HCC
    540. Contributions of telomere biology to human age-related disease
    541. Adult cardiac stem cells: identity, location and potential
    542. Human Population Studies of Transcriptome-wide Expression in Age-related Traits
    543. The Role of Age in Cellular Responses to Microenvironmental Cues as a Breast Cancer Susceptibility Factor
    544. The effects of chronic and acute toxicological exposures on the expression of the tumor suppressor p16INK4a
    545. p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism
    546. P13. 2
    547. The role of mitochondria in the regulation of gamma rays induced mTOR-dependent senescence
    548. Regulation of Forkhead BOX O tumor suppressors by Reactive Oxygen Species
    549. CSI-01–Cell Cycle & Checkpoints
    550. A novel approach towards finding regulatory microRNAs during phagosomal maturation in infection.
    551. The Impact of Physical Activity and Antioxidants on Tumor-Skeletal Muscle Crosstalk during Cancer: Deciphering Signaling Pathways Involved in Tumor Growth and …
    552. Par Proteins in Tumor Formation and Progression
    553. Identification and characterization of senescence-associated microRNAs in a mouse model of the XFE Progeroid Syndrome
    554. Immunoregulatory network and cancer-associated genes: molecular links and relevance to aging
    555. Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast …
    556. Telomere fragment induced amnion cell senescence: a contributor to parturition?
    557. Islet Biology/Insulin Secretion
    558. Telomere dysfunction: Role in arterial aging and hypertension
    559. Colorectal cancer-promoting activity of the senescent peritoneal mesothelium
    560. Senescent Carcinoma Associated Fibroblasts Up-regulate Interleukin 8 to Enhance Pancreatic Cancer Progression
    561. MOVD 2013
    562. The Role of Prolactin in the Cellular Response to DNA Damaging Agents
    563. Studies on the Developmental Changes in Parvalbumins of the Catfish, Heteropneustes fossilis (Bloch)
    564. Forum on aging and skeletal health: summary of the proceedings of an ASBMR workshop
    565. Analysis of temporal gene expression during Bacillus subtilis spore germination and outgrowth
    566. Analysis of gene expression during aging of CGNs in culture: implication of SLIT2 and NPY in senescence
    567. HIF1α regulates Mitochondrial biogenesis and Cellular senescence induced by Gamma Radiation
    568. Roles of senescence escape and epigenetic modifications in liver cancer
    569. Autophagy and inflammation in the pathogenesis of idiopathic dilated cardiomyopathy
    570. Interventions for age-related diseases: shifting the
    571. Differential expression of cellular senescence markers in the assessment of breast cancer development
    572. Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammation
    573. The role of Inhibitor of DNA binding 4 (Id4) in mammary gland development and breast cancer
    574. The Role of Photodynamic Therapy in Wound Healing and Scarring in Human Skin
    575. Melatonin maintains mitochondrial membrane potential and attenuates activation of initiator (casp‐9) and effector caspases (casp‐3/casp‐7) and PARP in UVR …
    576. Pathogenesis of intervertebral disc degeneration
    577. Thymic involution perturbs negative selection and leads to chronic inflammation
    578. Elucidating Molecular Changes in CD8+ T cells During Aging
    579. High-throughput Screening of Age-related Changes in Caenorhabditis elegans
    580. Causes, consequences, and reversal of immune system aging
    581. Senescence and apoptosis: dueling or complementary cell fates?
    582. Frequency of the cancer-resistant phenotype in SR/CR mice and the effect of litter seriation
    583. Understanding the roles of Non-homologous end joining and p53 after DNA damage
    584. IGF-binding protein 2–oncogene or tumor suppressor?
    585. Regulatory Mechanisms of NK-Cell-Mediated Immune Surveillance of Senescent Cells
    586. Suppression of autophagy during liver regeneration impairs energy charge and hepatocyte senescence in mice
    587. Mechanisms of tissue injury in autoimmune liver diseases
    588. Telomere dysfunction and senescence in the ageing lung and age-related lung disease
    589. HDAC 1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways
    590. Poster session 3
    591. The senescent cell induced bystander effect
    592. The Function and Regulation of Senescent Stromal-Derived Osteopontin
    593. Effects of chemotherapy and radiotherapy in rectal cancer: significance of different cellular outcomes in tumor behavior
    594. Polycomb Repressive Complex 1 Coordinates Enhanced Replication and Transcription in Transit Amplifying Chondrogenic Progenitors.
    595. Molecular Tuning Of Telomerase Activity In Senescent Human T Cells
    596. Role of squamous cell carcinoma antigen (SCCA) in oncogenic Ras-mediated tumorigenesis
    597. Increased oxidative and nitrative stress accelerates aging of the retinal vasculature in the diabetic retina
    598. The role of calcification regulatory proteins in the arterial stiffening of chronic kidney disease stages 3 & 4
    599. Age-like Phenotype of Microglia During HIV-1 Infection
    600. Characterisation of the molecular and functional changes
    601. The biology of aging: implications for diseases of aging and health care in the twenty-first century
    602. Cytokine and nitric oxide production in inflammatory arthritis
    603. Anti-Aging Effects of the Transcendental Meditation Program: Analysis of Ojas Level and Global Gene Expression
    604. Investigating the chondrogenic phenotype in clinically relevant cells: the effect of hTERT expression
    605. The diet-microbiota-metabolite axis regulates the host physiology
    606. Role of stromal fibroblasts in prostate carcinoma progression and metabolic reprogramming of cancer cells
    607. Regulation and inhibition of pro-tumorigenic microenvironments
    608. Metal-induced oxidative stress in human fibroblasts: A role in cellular ageing
    609. EVALUATING THE ROLE OF NF-êB SUPPRESSION IN AMELIORATING MAMMALIAN DISEASE: AN EXAMINATION OF INFLAMMATORY BOWEL DISEASE AND …
    610. Session held on 9 July 2016
    611. MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a p53 pathway preventing aneuploid cells propagation
    612. Molecular mechanism underlying the tumor-promoting functions of carcinoma-associated fibroblasts
    613. Understanding the pathophysiology and challenges of development of medical countermeasures for radiation-induced vascular/endothelial cell injuries: report of a …
    614. Regulation and Inhibition of Pro-Tumorigenic Microenvironments
    615. Changes in DNA methylation patterns in mammals with senescence, ageing and energy restriction
    616. Methamphetamine accelerates cellular senescence and aging through CYP2D-dependent stimulation of ceramide biosynthesis
    617. Program Committee: Sabine Fleming Markus Boehm Knut Schaekel Martin Metz Thomas Tueting
    618. Muscle ageing and anabolic response in the context of healthy and chronically HIV infected individuals
    619. Pathway Profiling Of Replicative And Induced Senescence
    620. Role of Tumor Suppressor DMP1 in the Initiation and Progression of Breast Cancer
    621. Revista de
    622. Endogenous retroelements in cellular senescence and related pathogenic processes: promising drug targets in age-related diseases
    623. Interactions between mitochondria and inflammatory factors during cellular senescence
    624. Using drug treatments to control genome behaviour in normal and Hutchinson-Gilford Progeria Syndrome fibroblasts, with and without hTERT immortalisation
    625. The chronic lymphocytic leukemia clone disrupts the bone marrow microenvironment
    626. Understanding vascular diseases: lessons from premature aging syndromes
    627. Epigenetic mechanisms of longevity and aging
    628. The role of DNA damage and repair in aging through the prism of Koch-like criteria
    629. Nutritional roles of selenium in cellular and mouse aging
    630. Anisotropy in the anodic oxidation of silicon in KOH solution
    631. Tumor Microenvironment
    632. Investigating the role of DNA polymerase beta in the aging phenotype of Down syndrome
    633. Diamond Sponsor
    634. EXTRACELLULAR MATRIX PROTEINS AND EPITHELIAL CELL PLASTICITY IN PROGRESSION OF BREAST AND PROSTATE CANCER
    635. Noncoding RNA in age-related cardiovascular diseases
    636. Identification and characterisation of telomere regulatory and signalling pathways after induction of telomere dysfunction
    637. Activity and controlled delivery of epigallocatechin 3-gallate in the treatment of degenerative disc disease
    638. State-of-the-Art Lecture
    639. Whose place is it?: examining the socio-spatial geography of obesity in young adults for an Australian context.
    640. Tumor Promoting Aspects of Senescence in Cancer Progression
    641. Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c‐kit+ cardiac progenitor cells by promoting miR‐675
    642. Higher-Order Unfolding of Peri/Centric Satellite Heterochromatin is an Early and Consistent Event in Cell Senescence: A Dissertation
    643. Poster session 2
    644. Hallmarks of progeroid syndromes: Lessons from mice and reprogrammed cells
    645. Proinflammatory cytokines in breast cancer: mechanisms of action and potential targets for therapeutics
    646. Nitrous oxide analgesia for bone marrow aspiration and biopsy–A randomized, controlled and patient blinded study
    647. 15th International Biennial Congress of the METASTASIS RESEARCH SOCIETY
    648. PLATFORM PRESENTATIONS
    649. The Genetic Landscapes of Inflammation-Driven Gastrointestinal Tract Cancers
    650. The senescent microenvironment promotes the emergence of heterogeneous cancer stem-like cells
    651. Mutual Reinforcement Between Telomere Capping and Canonical Wnt Pathway Activity in the Intestinal Stem Cell Niche
    652. The role of nitrosative and metabolic stress in vascular cell senescence
    653. Expression of p16INK4a in peripheral blood T‐cells is a biomarker of human aging
    654. MMP-2, MMP-9 production was significantly elevated by fibroblast cells isolated from rheumatoid arthritis patient when co-cultured with monocyte (THP-1) with …
    655. Evaluating the physiological reserves of older patients with cancer: the value of potential biomarkers of aging?
    656. POSTER PRESENTATIONS-Sunday, December 7
    657. Array-based transcriptional analysis of Clostridium sporogenes UC9000 during germination, cell outgrowth and vegetative life
    658. Pancreatic Dysfunction in Shwachman-Diamond Syndrome
    659. The wound healing, chronic fibrosis, and cancer progression triad
    660. Senescence suppressors: their practical importance in replicative lifespan extension in stem cells
    661. Contributions of Activated Hepatic Stellate Cells to Hepatocarcinogenesis
    662. Principles of Medical Management of Ulcerative Colitis
    663. Proceedings of the 26th annual meeting Chiba, Japan, October 18–20, 1984
    664. Roles of the ING1 Epigenetic Regulator in Breast Cancer
    665. Directions in Post-Traumatic Arthritis
    666. Metabolic regulation of intestinal stem cell function in Drosophila melanogaster
    667. Senescent endothelial cells: Potential modulators of immunosenescence and ageing
    668. Genotype distribution-based inference of collective effects in genome-wide association studies: insights to age-related macular degeneration disease …
    669. Sustained low-dose treatment with the histone deacetylase inhibitor LBH589 induces terminal differentiation of osteosarcoma cells
    670. The multiple roles of A-type lamins in cellular aging, cell cycle progression and the DNA damage response.
    671. Loss of the osteogenic differentiation potential during senescence is limited to bone progenitor cells and is dependent on p53
    672. Podocyte Injury Causes Chronic Kidney Disease in the Ercc1 Deficient Mouse Model of Accelerated Aging
    673. Biological ageing, inflammation and nutrition: how might they impact on systemic sclerosis?
    674. Detection of mesenchymal stem cells senescence by prelamin A accumulation at the nuclear level
    675. The role of chondrocyte senescence in osteoarthritis
    676. A senescent cell bystander effect: Senescence‐induced senescence
    677. Changes in regenerative capacity through lifespan
    678. Cancer, Senescence, and Aging: Translation from Basic Research to Clinics
    679. Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells
    680. Extracellular matrix and liver disease
    681. Programmed cell senescence during mammalian embryonic development
    682. Role of MicroRNA-146a in Vascular Inflammation and Atherosclerosis
    683. The effect of radiation on cellular ageing
    684. Programmed cell death in aging
    685. Update on the mechanisms of action of anti‑TNF‑α antibodies and their clinical implications in inflammatory bowel disease
    686. Clinical Investigation Program RCS-MED-300 (R1)
    687. Analysis of Temporal Gene Expression
    688. Postnatal Hdac3 deficiency in chondrocytes alters cortical bone architecture and increases articular cartilage thickness with age
    689. EMT and oxidative stress: a bidirectional interplay affecting tumor malignancy
    690. Regulation of 11β-Hydroxysteroid Dehydrogenase Type 1 and 2 in Rheumatoid Arthritis
    691. Impacts of Aging and Inflammation on Mycobacterium tuberculosis Control
    692. A review of melatonin as a suitable antioxidant against myocardial ischemia–reperfusion injury and clinical heart diseases
    693. Long noncoding RNAs (lncRNAs) and the molecular hallmarks of aging
    694. Integrative analysis of longevity, age-related diseases and aging-associated processes: Construction of the NetAge database
    695. SNEVPrp19/PSO4 deficiency increases PUVA‐induced senescence in mouse skin
    696. miR‐17, miR‐19b, miR‐20a, and miR‐106a are down‐regulated in human aging
    697. Pašatjaunošanās un paātrinātas novecošanās attiecības normālās un vēža šūnās pēc DNS bojājuma
    698. Circulating microRNAs as novel biomarkers for bone diseases–Complex signatures for multifactorial diseases?
    699. Aldehyde dehydrogenase activity of breast cancer stem cells is primarily due to isoform ALDH1A3 and its expression is predictive of metastasis
    700. Time-and Concentration-dependent response of a liver cell line to Benzo (a) pyrene
    701. Practical alternatives to chronic caloric restriction for optimizing vascular function with ageing
    702. Manipulation du métabolisme énergétique dans les leucémies aiguës myéloïdes: mitochondrie, apoptose et mécanisme d’action de la metformine
    703. Insulin-like growth factor binding protein-6 delays replicative senescence of human fibroblasts
    704. Intervention in Genotoxic Stress–Induced Senescence by Cordycepin Through Activation of eIF2α and Suppression of Sp1
    705. p62: linking protein homeostasis and the DNA damage response during ageing
    706. Molecular basis of Osteoarthritis and aspects of cellular senescence in disease
    707. Etude du facteur de réparation de l’ADN, Xeroderma pigmentosum du groupe C (XPC), dans les cellules souches hématopoïétiques
    708. HIV-1 Infection, Antiretroviral Therapies, and HIV-Associated Atherosclerosis
    709. The role of the transcriptional regulation of stromal cells in chronic inflammation
    710. Cell ageing: a flourishing field for neurodegenerative diseases
    711. Senescence of bone marrow mesenchymal stromal cells is accompanied by activation of p53/p21 pathway in myelodysplastic syndromes
    712. Rat retinal transcriptome: effects of aging and AMD-like retinopathy
    713. Aging of the liver: what this means for patients with HIV
    714. Pharmacology and biochemistry of salicylates and related drugs
    715. A report to inform the development of a clinical practice guideline for rehabilitation post total knee arthroplasty in a South African public hospital
    716. Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging‐related diseases
    717. Cellular responses to zinc involving the transcription factor ZNF658 and its target genes
    718. Determining the role of scavenger receptor class B type I as a source of cholesterol for de novo androgen synthesis in castration-resistant prostate cancer
    719. Antioxidant properties of mesalamine in colitis inhibit phosphoinositide 3-kinase signaling in progenitor cells
    720. Aging and the Host Response to Implanted Biomaterials
    721. A role for epigenetics in aging and the age-dependent response to ionizing radiation
    722. Interleukin 6 signaling regulates promyelocytic leukemia protein gene expression in human normal and cancer cells
    723. Mechanisms of microRNAs in atherosclerosis
    724. Mechanisms of Ageing and Development
    725. Telomeres and telomerase: their mechanisms of action and the effects of altering their functions
    726. Lifespan‐extending caloric restriction or m TOR inhibition impair adaptive immunity of old mice by distinct mechanisms
    727. Fourth International Ankle Symposium, July 16–18, 2009, Sydney, Australia
    728. Telomeres, Aging, and Nutrition
    729. Perspectives in pain research 2014: neuroinflammation and glial cell activation: the cause of transition from acute to chronic pain?
    730. On the Role of Prelamin A in the Heart
    731. Therapeutic effects and the underlying mechanisms of qing-dai powder against experimental colitis in mice
    732. Role of Gut Microbiome in the Modulation of Environmental Toxicants and Therapeutic Agents
    733. 43nd Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung eV (ADF)
    734. furanosidase f
    735. Stellate cells
    736. Pressure and cold pain threshold reference values in a large, young adult, pain-free population
    737. The ENRGISE Pilot Study Protocol
    738. A Comparative Analysis of Stress Granule Assembly in Replicative and Stress-Induced Premature Senescence
    739. Mutant lamin A links prophase to a p53 independent senescence program
    740. Identification and characterization of downstream effector protein (s) regulated by p53 and pRb
    741. Long-term efficacy of spironolactone on pain, mood, and quality of life in women with fibromyalgia: An observational case series
    742. Telomere shortening and immune activity in war veterans with posttraumatic stress disorder
    743. KAROLINSKA INSTITUTET, STOCKHOLM, SWEDEN
    744. Interplay between the myc oncoprotein, cyclin-dependent kinases and e3 ubiquitin ligases
    745. Calcitonin gene-related peptide (CGRP) in age-associated vascular inflammation and leukocyte trafficking
    746. The Contribution of DNA Interstrand Crosslinks to Aging
    747. ART. IV.–A Statistical Contribution to our knowledge of Abscess, and other Diseases Consequent upon the Lodgment of Foreign Bodies in the Appendix Vermiformis …
    748. Molecular Mechanisms of Cancer Progression: The Central Role of the Retinoblastoma Family Members
    749. Determination of Autoantibody IgG Subclass and Partial Sequence using Multi-affinity Purification with Multi-enzymatic Digestion by LC-MS
    750. Investigating the role of mitochondrial respiratory chain activity and mitochondrial DNA damage in skin ageing
    751. Prevalence of lumbo-pelvic pain and factors associated with it in cyclists in Johannesburg
    752. Health Ballistics: Multiple Reference Point Informed Probability Theory
    753. Translational Science 2014 Meeting Abstracts
    754. Proteomic profiling following cryopreservation
    755. Functional interaction between FOXO4 and p53 in response to oncogenic BRAF signaling
    756. Translational Science 2014 Meeting Abstracts
    757. Mechanism of Tumorigenesis by Cancer-Associated Mutations of INI1/SMARCB1, a Component of the SWI/SNF Chromatin Remodeling Complex
    758. Ecology of juvenile salmon in shallow tidal freshwater habitats in the vicinity of the Sandy River delta, lower Columbia River, 2008
    759. The role of bone morphogenetic protein 4 in the pathogenesis of choroidal neovascularization in age-related macular degeneration
    760. The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis
    761. Sarcopenic obesity or obese sarcopenia: a cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the …
    762. Cellular Senescence Biomarker p16INK4a+ Cell Burden in Thigh Adipose is Associated With Poor Physical Function in Older Women
    763. Expansion of adipose tissue‐derived stromal cells at “physiologic” hypoxia attenuates replicative senescence
    764. Age-induced changes in white, brite, and brown adipose depots: a mini-review
    765. adipose tissue inflammation in aging
    766. Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time
    767. Cellular aging contributes to failure of cold-induced beige adipocyte formation in old mice and humans
    768. Healthy ageing in 2016: Obesity in geroscience—is cellular senescence the culprit?
    769. Micro-RNAS regulate metabolic syndrome-induced senescence in porcine adipose tissue-derived mesenchymal stem cells through the P16/MAPK pathway
    770. Therapeutic doses of doxorubicin induce premature senescence of human mesenchymal stem cells derived from menstrual blood, bone marrow and adipose tissue
    771. Growth hormone’s effect on adipose tissue: quality versus quantity
    772. Aging, cell senescence, and chronic disease: emerging therapeutic strategies
    773. Neovascular deterioration, impaired NADPH oxidase and inflammatory cytokine expression in adipose-derived multipotent cells from subjects with metabolic …
    774. Dietary restriction ameliorates age-related increase in DNA damage, senescence and inflammation in mouse adipose tissuey
    775. Fisetin is a senotherapeutic that extends health and lifespan
    776. adipose tissue-derived extracellular fraction characterization: biological and clinical considerations in regenerative medicine
    777. Fat depot-specific differences of macrophage infiltration and cellular senescence in obese bovine adipose tissues
    778. Source of chronic inflammation in aging
    779. Aging impairs beige adipocyte differentiation of mesenchymal stem cells via the reduced expression of Sirtuin 1
    780. Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice
    781. Reduction of premature aging markers after gastric bypass surgery in morbidly obese patients
    782. Age-and tissue-specific expression of senescence biomarkers in mice
    783. Senolytics improve physical function and increase lifespan in old age
    784. Silencing of the small GTPase DIRAS3 induces cellular senescence in human white adipose stromal/progenitor cells
    785. ANGPTL2―A New Causal Player in Accelerating Heart Disease Development in the Aging―
    786. Melatonin prevents senescence of canine adipose-derived mesenchymal stem cells through activating NRF2 and inhibiting ER stress
    787. Cellular senescence: a translational perspective
    788. Rejuvenating senolytics
    789. Regulation of lipogenesis in human adipose tissue: Effect of metabolic stress, dietary intervention and aging.
    790. Cellular senescence in osteoarthritis pathology
    791. Metabolic memory of dietary restriction ameliorates DNA damage and adipocyte size in mouse visceral adipose tissue
    792. Aging of Brown and Beige/Brite adipose tissue
    793. Impact of senescence‐associated secretory phenotype and its potential as a therapeutic target for senescence‐associated diseases
    794. Cellular Senescence: At the Nexus of Mechanisms of Age-and Obesity-Related Metabolic Dysfunction
    795. The Progressive Low Chronic Inflammation On Oral Tissues In Elderly
    796. High Circulating Levels of ANGPTL2: Beyond a Clinical Marker of Systemic Inflammation
    797. Basic research: killing the old: cell senescence in atherosclerosis
    798. Cellular senescence: implications for metabolic disease
    799. Melatonin regulates PARP 1 to control the senescence‐associated secretory phenotype (SASP) in human fetal lung fibroblast cells
    800. Examination of the Inhibitory Protein P21 in Omento Fat as an Indication of Adipocyte Proliferation
    801. Augmentation of Dermal Wound Healing by adipose tissue-Derived Stromal Cells (ASC)
    802. Cell-free therapy with the secretome of adipose tissue-derived stem cells in rats’ frozen-thawed ovarian grafts
    803. The Complexity of adipose tissue
    804. Targeting cellular senescence prevents age-related bone loss in mice
    805. Targeting our aging cells to treat metabolic disease
    806. Different response to hypoxia of adipose-derived multipotent cells from obese subjects with and without metabolic syndrome
    807. Mitochondria in cell senescence: is mitophagy the weakest link?
    808. Diabetes and Adipocyte Dysfunction
    809. Nonalcoholic fatty liver disease promotes hepatocellular carcinoma through direct and indirect effects on hepatocytes
    810. Short-term sustained hyperglycaemia fosters an archetypal senescence-associated secretory phenotype in endothelial cells and macrophages
    811. Senescence and aging: Causes, consequences, and therapeutic avenues
    812. A summary of the Proceedings of the Thirteenth International Symposium on the Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria July 17–22, 2016
    813. Killing the old: cell senescence in atherosclerosis
    814. New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463
    815. Parallels Between Skeletal Muscle and Bone Aging
    816. Aging, obesity, and inflammatory age-related diseases
    817. Molecular pathology endpoints useful for aging studies
    818. Cellular senescence in postmitotic cells: beyond growth arrest
    819. Senescent cells: an emerging target for diseases of ageing
    820. Prevention of senescence in vasculature through quiescence
    821. Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri
    822. Inflammageing and metaflammation: the yin and yang of type 2 diabetes
    823. Chronic inflammation and sarcopenia: A regenerative cell therapy perspective
    824. Ageing: from inflammation to cancer
    825. Senotherapy: growing old and staying young?
    826. Down-regulation of guanylate binding protein 1 causes mitochondrial dysfunction and cellular senescence in macrophages
    827. Cellular senescence: Molecular mechanisms and pathogenicity
    828. Anti-inflammatory effect of Chang-An-Shuan on TNBS-induced experimental colitis in rats
    829. Senescent B cells in aging and age-related diseases: their role in the regulation of antibody responses
    830. The fountain of youth by targeting senescent cells?
    831. HIV-associated cellular senescence: a contributor to accelerated aging
    832. Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
    833. Activated tissue-resident mesenchymal stromal cells regulate natural killer cell immune and tissue-regenerative function
    834. Immunosenescence induced by plasma from individuals with obesity caused cell signaling dysfunction and inflammation
    835. Circadian Disruption, Sleep Loss, and Low-Grade Inflammation
    836. Histone MacroH2A1: a chromatin point of intersection between fasting, senescence and cellular regeneration
    837. PPARα regulates tumor cell proliferation and senescence via a novel target gene carnitine palmitoyltransferase 1C
    838. p16 (Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli
    839. Novel Role of Blackberries in Senescence and Atherosclerosis in ApoE-/-Mice
    840. The Role of Na/K-ATPase Signaling in Oxidative Stress Related to Aging: Implications in Obesity and Cardiovascular Disease
    841. Cellular senescence in renal ageing and disease
    842. Quantitative analysis of cellular senescence in culture and in vivo
    843. Ketone bodies mimic the life span extending properties of caloric restriction
    844. Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2‐independent mechanism
    845. Gut microbiota and mTOR signaling: insight on a new pathophysiological interaction
    846. Gut microbiota, fatty liver disease, and hepatocellular carcinoma
    847. Increase in tumor suppressor Arf compensates gene dysregulation in in vitro aged adipocytes
    848. Inhibiting cellular senescence: a new therapeutic paradigm for age-related osteoporosis
    849. The Na/K-ATPase oxidant amplification loop regulates aging
    850. Role of lncRNAs in aging and age‐related diseases
    851. TNFα-senescence initiates a STAT-dependent positive feedback loop, leading to a sustained interferon signature, DNA damage, and cytokine secretion
    852. Gut microbiota-mediated inflammation in obesity: a link with gastrointestinal cancer
    853. The impact of senescence-associated T cells on immunosenescence and age-related disorders
    854. Study on the therapeutic effects of salicylazosulfapyridine on ulcerative colitis in rats
    855. Emerging metabolic risk factors in hepatocellular carcinoma and their influence on the liver microenvironment
    856. Low-grade inflammation in the relationship between sleep disruption, dysfunctional adiposity, and cognitive decline in aging
    857. Musculoskeletal senescence: a moving target ready to be eliminated
    858. Inflammatory response in the CNS: friend or foe?
    859. Inflammation-accelerated senescence and the cardiovascular system: mechanisms and perspectives
    860. Biphasic modeling of mitochondrial metabolism dysregulation during aging
    861. Myeloid-derived suppressor cells (MDSC): an important partner in cellular/tissue senescence
    862. Mitochondrial peptides modulate mitochondrial function during cellular senescence
    863. Senescence of mesenchymal stem cells
    864. Sirtuins, a promising target in slowing down the ageing process
    865. Endothelin receptor type b blocker attenuates severity of osteoarthritis by clearance of senescent cells
    866. The Rbm38-p63 feedback loop is critical for tumor suppression and longevity
    867. Identification of senescent cell surface targetable protein DPP4
    868. Caloric Restriction, Sirtuins, and Ageing
    869. 5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR
    870. SCAMP4 enhances the senescent cell secretome
    871. Age-related changes in glucose metabolism, hyperglycemia, and cardiovascular risk
    872. Investigating the Role of NRIP1 in Skin Aging: Depletion of NRIP1 Delays Senescence, Reduces Inflammation and Enhances Autophagy in Adipocytes
    873. The role of cellular senescence in aging through the prism of Koch-like criteria
    874. Heat-induced extracellular HSP72 release is blunted in elderly diabetic people compared with healthy middle-aged and older adults, but it is partially restored by …
    875. Drosophila as a Model to Study the Link between Metabolism and Cancer
    876. Oxidative stress-mediated senescence in mesenchymal progenitor cells causes the loss of their fibro/adipogenic potential and abrogates myoblast fusion
    877. Immune Senescence and Inflammaging in Neurological Diseases
    878. Inflammaging and human longevity in the omics era
    879. Role of sphingolipids in senescence: implication in aging and age-related diseases
    880. Mitochondrial activity and dynamics changes regarding metabolism in ageing and obesity
    881. Premature physiologic aging as a paradigm for understanding increased risk of adverse health across the lifespan of survivors of childhood cancer
    882. The molecular intersection between senescence and major depression in the elderly
    883. Senescent cells: a new Achilles’ heel to exploit for cancer medicine?
    884. From cellular senescence to age-associated diseases: miRNAs as tools and targets for healthy ageing
    885. Attenuation of inflammation and cartilage degradation by sulfasalazine-containing hyaluronic acid on osteoarthritis rat model
    886. Ripk3 regulates cardiac microvascular reperfusion injury: the role of IP3R-dependent calcium overload, XO-mediated oxidative stress and F-action/filopodia-based …
    887. The dual role of cellular senescence in developing tumors and their response to cancer therapy
    888. Identification of new genes associated to senescent and tumorigenic phenotypes in mesenchymal stem cells
    889. Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing
    890. Cellular senescence in osteoarthritis and anti-aging strategies
    891. Downregulation of miR-130b~ 301b cluster is mediated by aberrant promoter methylation and impairs cellular senescence in prostate cancer
    892. Hydrogen sulfide ameliorates aging-associated changes in the kidney
    893. The peritoneal “soil” for a cancerous “seed”: a comprehensive review of the pathogenesis of intraperitoneal cancer metastases
    894. Aging mechanisms and intervention targets
    895. Inflammaging and ‘Garb-aging’
    896. NLRP3 inflammasome activation in inflammaging
    897. Mechanisms and functions of cellular senescence
    898. The Effects of the Senescent Preadipocyte Secretome on Skeletal Muscle Cells
    899. Ras signaling in aging and metabolic regulation
    900. Cellular senescence in brain aging and neurodegenerative diseases: evidence and perspectives
    901. Anthracycline cardiotoxicity: looking for new therapeutic approaches targeting cell senescence?
    902. Coenzyme Q10 prevents senescence and dysfunction caused by oxidative stress in vascular endothelial cells
    903. Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and relation to vascular endothelial function
    904. Senescent cells and osteoarthritis: a painful connection
    905. Oncogenic KRAS and the Inflammatory Micro-Environment in Pancreatic Cancer
    906. Linking cellular stress responses to systemic homeostasis
    907. Cellular senescence, senescence-associated secretory phenotype, and chronic kidney disease
    908. With great age comes great metastatic ability: ovarian cancer and the appeal of the aging peritoneal microenvironment
    909. Lipometabolism and Glycometabolism in Liver Diseases
    910. A null mutation in SERPINE1 protects against biological aging in humans
    911. CELLULAR STRESS RESPONSE GENES IN ALZHEIMER’S DISEASE: INSIGHTS FROM GENOME-WIDE ASSOCIATION STUDIES
    912. Osteoarthritis Biology
    913. Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis
    914. Oxidative stress in mesenchymal stem cell senescence: regulation by coding and noncoding RNAs
    915. Divergent mechanisms of metabolic dysfunction drive fibroblast and T-cell senescence
    916. Is the secret for a successful aging to keep track of cancer pathways?
    917. Acute genotoxic stress-induced senescence in human mesenchymal cells drives a unique composition of senescence messaging secretome (SMS)
    918. HIF1α deletion facilitates adipose stem cells to repair renal fibrosis in diabetic mice
    919. Deletion of Nrip1 Extends Female Mice Longevity, Increases Autophagy, and Delays Cell Senescence
    920. Calcium signaling and cellular senescence
    921. Stress, cell senescence and organismal ageing
    922. Senescence as a novel mechanism involved in β-adrenergic receptor mediated cardiac hypertrophy
    923. Activation of sirtuin 1 by catalpol-induced down-regulation of microRNA-132 attenuates endoplasmic reticulum stress in colitis
    924. Secondary Unconjugated Bile Acids Induce Hepatic Stellate Cell Activation
    925. MicroRNA regulation of oxidative stress-induced cellular senescence
    926. Yields and chondrogenic potential of primary synovial mesenchymal stem cells are comparable between rheumatoid arthritis and osteoarthritis patients
    927. The spectrum of fundamental basic science discoveries contributing to organismal aging
    928. Seasonal variation in vitamin D in association with age, inflammatory cytokines, anthropometric parameters, and lifestyle factors in older adults
    929. The imbalance between n-6/n-3 polyunsaturated fatty acids and inflammatory bowel disease: a comprehensive review and future therapeutic perspectives
    930. Aging, inflammation and the environment
    931. Rejuvenation of aged hematopoietic stem cells
    932. Pathogenesis of wound healing disorders in the elderly
    933. Microvesicles as potential biomarkers for the identification of senescence in human mesenchymal stem cells
    934. Aging and the immune system: An overview
    935. The light and shadow of senescence and inflammation in cardiovascular pathology and regenerative medicine
    936. BBA-Molecular Basis of Disease
    937. The impact of the Standard American Diet in rats: Effects on behavior, physiology and recovery from inflammatory injury
    938. The macroH2A1. 1–PARP1 axis at the intersection between stress response and metabolism
    939. Integrative Cardiovascular Physiology and Pathophysiology: Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and …
    940. Circulating markers of ageing and allostatic load: A slow train coming
    941. Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition
    942. The Role of p16-Positive Senescent Cells in an Age-Related Disease and Aging Itself
    943. Regulation of normal and leukemic stem cells through cytokine signaling and the microenvironment
    944. Autophagy and the cell biology of age-related disease
    945. Using comparative biology to understand how aging affects mitochondrial metabolism
    946. Maternal obesity impairs skeletal development in adult offspring
    947. Cellular senescence links aging and diabetes in cardiovascular disease
    948. Apelin/APJ system: A novel promising target for anti-aging intervention
    949. The gut–liver axis and the intersection with the microbiome
    950. Targeting senescent cells in fibrosis: pathology, paradox, and practical considerations
    951. A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse
    952. Mesenchymal stem cells secretory responses: senescence messaging secretome and immunomodulation perspective
    953. Cell cycle and apoptosis regulator 2 at the interface between DNA damage response and cell physiology
    954. Mechanisms of normal tissue injury from irradiation
    955. Immunological aspects of age-related diseases
    956. Happily (n) ever after: aging in the context of oxidative stress, proteostasis loss and cellular senescence
    957. Senescence in hepatic stellate cells as a mechanism of liver fibrosis reversal: a putative synergy between retinoic acid and PPAR-gamma signalings
    958. Senescence in health and disease
    959. Linking a role of lncRNAs (long non-coding RNAs) with insulin resistance, accelerated senescence, and inflammation in patients with type 2 diabetes
    960. Emerging players at the intersection of chondrocyte loss of maturational arrest, oxidative stress, senescence and low-grade inflammation in osteoarthritis
    961. Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing
    962. Immunologic
    963. Nutrient sensing pathways as therapeutic targets for healthy ageing
    964. Articular cartilage aging-potential regenerative capacities of cell manipulation and stem cell therapy
    965. Fibroblast activation and senescence in oral cancer
    966. MicroRNAs and the metabolic hallmarks of aging
    967. Genomic profiling and metabolic homeostasis in primary liver cancers
    968. Mitochondria, oxidative stress and innate immunity
    969. Human menstrual blood: a renewable and sustainable source of stem cells for regenerative medicine
    970. Balancing between aging and cancer: molecular genetics meets traditional Chinese medicine
    971. The mechanism of alopolysaccharide protecting ulceralive colitis
    972. Glutathione peroxidase 3 delivered by hiPSC-MSCs ameliorated hepatic IR injury via inhibition of hepatic senescence
    973. Novel strategies for anti-aging drug discovery
    974. Cellular and molecular mechanisms of asthma and COPD
    975. The role of kinase modulators in cellular senescence for use in cancer treatment
    976. Inflammaging
    977. Sex-specific differences in hypertension and associated cardiovascular disease
    978. Comparison of several commonly used detection indicators of cell senescence
    979. Loss of SATB1 Induces a p21 Dependent Cellular Senescence Phenotype in Dopaminergic Neurons
    980. Effects of bioactive compounds on senescence and components of senescence associated secretory phenotypes in vitro
    981. The integration of inflammaging in age-related diseases
    982. Sphingolipids at the Crossroads of NAFLD and Senescence
    983. Mitochondria, telomeres and cell senescence: implications for lung ageing and disease
    984. SASP+adipose+tissue+&ots=A6ts81jdo4&sig=3CwomOd726aFBjPd4YNvvOWa1Uk” target=”_blank” rel=”noopener” data-saferedirecturl=”https://www.google.com/url?hl=en&q=https://books.google.com/books?hl%3Den%26lr%3Dlang_en%26id%3D3HCQDwAAQBAJ%26oi%3Dfnd%26pg%3DPA69%26dq%3DSASP%2Badipose%2Btissue%2B%26ots%3DA6ts81jdo4%26sig%3D3CwomOd726aFBjPd4YNvvOWa1Uk&source=gmail&ust=1579364469122000&usg=AFQjCNHEnnkq5JBN1ZAJuDAnchZTXr-Lbw”>Cellular Senescence and their Role in Liver Metabolism in Health and Disease: Overview and Future Directions
    985. Mechanisms of dysfunction in the aging vasculature and role in age-related disease
    986. Knockdown of IL-8 Provoked Premature Senescence of Placenta-Derived Mesenchymal Stem Cells
    987. Treating Age-Related Diseases with Somatic Stem Cells
    988. Controlling insulin resistance through modulation of interplay between mediators of cellular senescence: A mathematical study
    989. Mechanisms of renal fibrosis
    990. Nitric oxide-heat shock protein axis in menopausal hot flushes: neglected metabolic issues of chronic inflammatory diseases associated with deranged heat shock …
    991. Characterization of brusatol self-microemulsifying drug delivery system and its therapeutic effect against dextran sodium sulfate-induced ulcerative colitis in mice
    992. Innate immunity and cellular senescence: The good and the bad in the developmental and aged brain
    993. Stellate cells in tissue repair, inflammation, and cancer
    994. YAP inhibits the apoptosis and migration of human rectal cancer cells via suppression of JNK-Drp1-mitochondrial fission-HtrA2/Omi pathways
    995. DHA-enriched fish oil upregulates cyclin-dependent kinase inhibitor 2A (P16INK) expression and downregulates telomerase activity without modulating effects of …
    996. Antioxidant and anti-senescence effect of metformin on mouse olfactory ensheathing cells (mOECs) may be associated with increased brain-derived neurotrophic …
    997. Senescent intervertebral disc cells exhibit perturbed matrix homeostasis phenotype
    998. Procancerogenic activity of senescent cells: A case of the peritoneal mesothelium
    999. Key proteins and pathways that regulate lifespan
    1000. miRNAs in stem cell aging and age-related disease
    1001. Unhealthy Stem Cells: When Health Conditions Upset Stem Cell Properties
    1002. Cellular senescence and inflammaging in age-related diseases
    1003. Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts
    1004. Isolation and prolonged expansion of oral mesenchymal stem cells under clinical-grade, GMP-compliant conditions differentially affects “stemness” properties
    1005. Extracellular vesicles in the tumor microenvironment: therapeutic resistance, clinical biomarkers, and targeting strategies
    1006. Down-regulation of hepatic MBOAT7 by hyperinsulinemia favors steatosis development
    1007. The Impact of the Mediterranean Diet on Aging, Frailty, and Longevity
    1008. The epigenetics of inflammaging: The contribution of age-related heterochromatin loss and locus-specific remodelling and the modulation by environmental …
    1009. Program & Book of Abstracts: IUBMB Advanced School Nutrition, Metabolism and Aging 2018
    1010. Immune senescence: significance of the stromal microenvironment
    1011. Extracellular vesicles and aging
    1012. Senescence and cell death in chronic liver injury: roles and mechanisms underlying hepatocarcinogenesis
    1013. Energy to Fight Infection
    1014. Senescent, dysfunctional human cardiac progenitor cells (CPCs) accumulate in the aged heart and elimination of senescent cells enhances CPC activation and …
    1015. Cellular senescence, geroscience, cancer and beyond
    1016. Stem Cell Applications in Rejuvenation
    1017. Progeria and accelerated cardiovascular aging
    1018. Camellia Oil (Camellia oleifera Abel.) Modifies the Composition of Gut Microbiota and Alleviates Acetic Acid-Induced Colitis in Rats
    1019. Ionizing radiation-induced cellular senescence promotes tissue fibrosis after radiotherapy. A review
    1020. Major trauma and acceleration of the ageing process
    1021. Inflammatory bowel diseases: Current therapeutic approaches and potential of using stem cells
    1022. PINK1-PARK2-mediated mitophagy in COPD and IPF pathogeneses
    1023. Obesity, Metabolism, and Aging: A Multiscalar Approach
    1024. PPARγ-activation increases intestinal M1 macrophages and mitigates formation of serrated adenomas in mutant KRAS mice
    1025. Current Approaches of Anti-inflammatory-Dependent Antiaging Strategies
    1026. Immunosenescence in neurocritical care
    1027. Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice
    1028. Cellular senescence: a view throughout organismal life
    1029. Effect of Mst1 on endometriosis apoptosis and migration: role of Drp1-related mitochondrial fission and parkin-required mitophagy
    1030. Ceramide synthase 4: a novel metabolic regulator of oncogene-induced senescence
    1031. Regulation and function of p53: A perspective from Drosophila studies
    1032. Relevance of the p53–MDM2 axis to aging
    1033. Administration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice
    1034. Exercise and bone health across the lifespan
    1035. Urothelial senescence in the pathophysiology of diabetic bladder dysfunction-a novel hypothesis
    1036. Gut microbiota’s relationship with liver disease and role in hepatoprotection by dietary natural products and probiotics
    1037. Developmental programming of aging trajectory
    1038. Senescent microvesicles: a novel advance in molecular mechanisms of atherosclerotic calcification
    1039. Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging
    1040. Disruptions in gut microbial-host co-metabolism and the development of metabolic disorders
    1041. In vivo effects of DNA lesions in Nucleotide Excision Repair deficient mice
    1042. Bone Research Society, Annual Meeting 2017 Proceedings
    1043. The clinical potential of senolytic drugs
    1044. Anti-senescence compounds: a potential nutraceutical approach to healthy aging
    1045. Loss of ovarian hormones and accelerated somatic and mental aging
    1046. Inflammation and premature aging in advanced chronic kidney disease
    1047. C. elegans eats its own intestine to make yolk leading to multiple senescent pathologies
    1048. Aging With HIV and Oxidative Stress
    1049. Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine
    1050. DICER1: a key player in rheumatoid arthritis, at the crossroads of cellular stress, innate immunity, and chronic inflammation in aging
    1051. miR-125a induces apoptosis, metabolism disorder and migrationimpairment in pancreatic cancer cells by targeting Mfn2-related mitochondrial fission
    1052. Biology of Aging
    1053. Cellular senescence in tissue repair: every cloud has a silver lining
    1054. Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis
    1055. Automated image analysis detects aging in clinical-grade mesenchymal stromal cell cultures
    1056. Cellular senescence, neurological function, and redox state
    1057. Mesenchymal stem cell therapy protects lungs from radiation-induced endothelial cell loss by restoring superoxide dismutase 1 expression
    1058. Mechanisms of vascular aging
    1059. Environmental and Physiological Cues on the Hypothalamus During Aging
    1060. Reaction time in healthy elderly is associated with chronic low-grade inflammation and advanced glycation end product
    1061. Phospholipase C delta 4 (PLCδ4) is a nuclear protein involved in cell proliferation and senescence in mesenchymal stromal stem cells
    1062. Epigenetics in cardiac fibrosis: emphasis on inflammation and fibroblast activation
    1063. Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells
    1064. PGC-1α protects RPE cells of the aging retina against oxidative stress-induced degeneration through the regulation of senescence and mitochondrial quality control …
    1065. Pro-resolving lipid mediators: Agents of anti-ageing?
    1066. Hyperglycaemia Stress-Induced Renal Injury is Caused by Extensive Mitochondrial Fragmentation, Attenuated MKP1 Signalling, and Activated JNK-CaMKII-Fis1 …
    1067. Energy restriction in renal protection
    1068. Targeting cancer stem cells and their niche: Perspectives for future therapeutic targets and strategies
    1069. Senescence-associated microRNAs
    1070. Cellular senescence and liver disease: Mechanisms and therapeutic strategies
    1071. Gene expression hallmarks of cellular ageing
    1072. Facing up to the global challenges of ageing
    1073. Melatonin and inflammation—Story of a double‐edged blade
    1074. The role of myeloid-derived suppressor cells (MDSC) in the inflammaging process
    1075. Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption
    1076. In vivo and in vitro study on the efficacy of terpinen-4-ol in dextran sulfate sodium-induced mice experimental colitis
    1077. The emerging roles of microRNAs in stem cell aging
    1078. Bone marrow-derived mesenchymal stromal cells promote colorectal cancer cell death under low-dose irradiation
    1079. Umbilical cord–derived mesenchymal stromal cell–conditioned medium exerts in vitro antiaging effects in human fibroblasts
    1080. Tetraploidy in cancer and its possible link to aging
    1081. Senescent cells: a therapeutic target for cardiovascular disease
    1082. Non-Cell autonomous effects of the senescence-associated secretory phenotype in cancer therapy
    1083. The effect of green tea extract compounds on regulation of glucose homoeostasis in insulin-sensitive and breast cancer cells
    1084. Mammalian STE20-Like Kinase 1 Deletion Alleviates Renal Ischaemia-Reperfusion Injury via Modulating Mitophagy and the AMPK-YAP Signalling Pathway
    1085. Immunosenescence: the role of aging in the predisposition to neuro-infectious complications arising from the treatment of multiple sclerosis
    1086. SIPS as a model to study age-related changes in proteolysis and aggregate formation
    1087. Epithelial cell cycle behaviour in the injured kidney
    1088. Immunosenescence and Ageing in HIV
    1089. Long-term persistent organic pollutants exposure induced telomere dysfunction and senescence-associated secretary phenotype
    1090. Aging, Telomere Integrity, and Antioxidant Food
    1091. Advances in tendon mechanobiology
    1092. DICER1: a key player in rheumatoid arthritis, at the crossroads of cellular stress, innate immunity and chronic inflammation in ageing
    1093. G Protein-Coupled Receptor Systems as Crucial Regulators of DNA Damage Response Processes
    1094. NR4A1 contributes to high-fat associated endothelial dysfunction by promoting CaMKII-Parkin-mitophagy pathways
    1095. Age, gender and UV-exposition related effects on gene expression in in vivo aged short term cultivated human dermal fibroblasts
    1096. Role Of COX2 In Cellular Senescence
    1097. Tissue aging: the integration of collective and variant responses of cells to entropic forces over time
    1098. Counterregulatory Effects of Ptx3 on Inflammation and Cellular Aging
    1099. Resveratrol as an Activator or Inhibitor of Enzymes and Proteins
    1100. Induction of a senescence-like phenotype in cultured human fetal microglia during HIV-1 infection
    1101. Vitamin C, aging and Alzheimer’s disease
    1102. Screening and treating prostate cancer in the older patient: decision making across the clinical spectrum
    1103. Mechanisms driving the ageing heart
    1104. Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo
    1105. Biomedical Research in Aging
    1106. Modelling of mitochondrial metabolism in breast cancer
    1107. Age and age-related diseases: role of inflammation triggers and cytokines
    1108. Inducers of senescence, toxic compounds, and Senolytics: the multiple faces of Nrf2-activating phytochemicals in Cancer adjuvant therapy
    1109. Epidermal Growth Factor Therapy Impact on Scar Tissue Resilience of Diabetic Lower Limbs Ulcers-An Enlightening Hypothesis
    1110. The Impact of Membrane Phospholipid Composition and Extracellular Vesicles on the Immunoregulative Properties of Human Mesenchymal Stromal Cells
    1111. Autophagy regulation in preeclampsia: Pros and cons
    1112. The interplay between immunity and aging in Drosophila
    1113. Reversing the immune ageing clock: lifestyle modifications and pharmacological interventions
    1114. Nitric Oxide Regulates H2O2-Induced Senescence via S-Nitrosylation of NF-κB in Endothelial Cells
    1115. Biliary bile acids in hepatobiliary injury–What is the link?
    1116. Cover ImageReport and Abstracts of the 14th Meeting of IIM, the Interuniversity Institute of Myology,-Assisi (Italy), October 12-15, 2017
    1117. Role of the inflammation-autophagy-senescence integrative network in osteoarthritis
    1118. Novel treatment strategies for chronic kidney disease: insights from the animal kingdom
    1119. Aging hallmarks: the benefits of physical exercise
    1120. mTORC inhibitors as broad-spectrum therapeutics for age-related diseases
    1121. Bioactive nutrients and nutrigenomics in age-related diseases
    1122. The nematode Caenorhabditis elegans as a model for aging research
    1123. Sleep health: reciprocal regulation of sleep and innate immunity
    1124. Osteoblast suppression in multiple myeloma bone disease
    1125. Yap regulates gastric cancer survival and migration via SIRT1/Mfn2/mitophagy
    1126. Hypoxia Prevents Mitochondrial Dysfunction and Senescence in Human Cardiac Progenitor Cells
    1127. Senolytika-současný stav
    1128. In vivo and in vitro study of pancreatic islets aging: impact of endothelial senescence and microparticles on islet function
    1129. Mechanisms of Obesity-related Hepatocarcinogensis
    1130. Identification of rare and common genetic variants associated with hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: mechanisms and clinical …
    1131. Nutrient supply affects the mRNA expression profile of the porcine skeletal muscle
    1132. Application of kinase inhibitors for anti-aging intervention
    1133. Telomeres, aging and exercise: guilty by association?
    1134. Long noncoding RNAs and RNA-binding proteins in oxidative stress, cellular senescence, and age-related diseases
    1135. Effects of exercise on inflammatory, oxidative, and neurotrophic biomarkers on cognitively impaired individuals diagnosed with dementia or mild cognitive impairment …
    1136. DNA damage-induced inflammation and nuclear architecture
    1137. Hormonal modulation of ageing skin microstructure and mechanical properties
    1138. The protective effects of Poria cocos-derived polysaccharide CMP33 against IBD in mice and its molecular mechanism
    1139. Prospects of Pharmacological Interventions to Organismal Aging
    1140. Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence
    1141. Investigating senescence in cellular plasticity and tissue regeneration
    1142. DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age
    1143. Targeting mitochondria to counteract age-related cellular dysfunction
    1144. Attenuated Macrophage Infiltration in Glomeruli of Aged Mice Resulting in Ameliorated Kidney Injury in Nephrotoxic Serum Nephritis
    1145. Mechanisms of Action of Drugs for Treating Endothelial Dysfunction in Diabetes Mellitus
    1146. Nutrient supply affects the mRNA expression profile of the porcine skeletal muscle
    1147. Oncogenic roles of the PI3K/AKT/mTOR axis
    1148. Organ reserve, excess metabolic capacity, and aging
    1149. Studies of Novel Factors from Fetal Mesenchymal Stem Cell and Their Applications in Bone and Cartilage Repair
    1150. Secreted α-Klotho maintains cartilage tissue homeostasis by repressing NOS2 and ZIP8-MMP13 catabolic axis
    1151. Extracellular vesicles and their miRNA cargo in ageing and age-associated diseases
    1152. The Pathobiology of Osteoarthritis in Obesity: The Role of Synovial Inflammation, Joint Insulin Resistance, and Dysbiosis of the Gut Microbiome
    1153. Osteobiology of aging
    1154. PTEN enhances nasal epithelial cell resistance to TNFα‑induced inflammatory injury by limiting mitophagy via repression of the TLR4‑JNK‑Bnip3 pathway
    1155. Recent advances in understanding cross-talk between Bile Acids and Gut Microbiota. Open J Proteom Genom 3 (1): 024-034
    1156. Interleukin 1 gene polymorphism and susceptibility to disease
    1157. Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice
    1158. Patent Highlights February–March 2018
    1159. Microbiome and NAFLD: potential influence of aerobic fitness and lifestyle modification
    1160. Advances in Therapeutic Approaches to Extend Healthspan: a perspective from the 2nd Scripps Symposium on the Biology of Aging
    1161. Workshop on Synergies Between Alzheimer’s Research and Clinical Gerontology and Geriatrics: Current Status and Future Directions
    1162. WSB1 overcomes oncogene-induced senescence by targeting ATM for degradation
    1163. A double-blind, randomized trial on the effect of a broad-spectrum dietary supplement on key biomarkers of cellular aging including inflammation, oxidative …
    1164. Innate and adaptive immunity in atherosclerosis
    1165. Functional interaction between melatonin signaling and noncoding RNAs
    1166. Shared molecular and cellular mechanisms of premature ageing and ageing-associated diseases
    1167. Nicotinamide Phosphoribosyltransferase In Smooth Muscle Cells And Aortic Integrity
    1168. Analysis of Aortic Valve Function in the Absence of Endothelial Retinoblastoma Protein
    1169. Oxidative stress and the epigenetics of cell senescence: Insights from progeroid syndromes
    1170. The RNA world of human ageing
    1171. A system for the expression and release of heterologous proteins from the core of Bacillus subtilis spores
    1172. THE CANCER AND BONE SOCIETY (CABS) ANNUAL CONFERENCE
    1173. The versatile role of exosomes in cancer progression: diagnostic and therapeutic implications
    1174. Vascular aging: molecular mechanisms and potential treatments for vascular rejuvenation
    1175. The interplay between immunity and aging in Drosophila
    1176. Submission to the British Geriatrics Society Amulree Prize 2017
    1177. The cancer and bone society (CABS) annual conference Sheraton indianapolis hotel at keystone crossing. Indianapolis, Indiana. May 4-6, 2017
    1178. AAVvector-mediated in vivo reprogramming into pluripotency
    1179. Age-Related Adverse Inflammatory and Metabolic Changes Begin Early in Adulthood
    1180. Toll-like receptor-4 signaling pathway in aorta aging and diseases:“its double nature”
    1181. The Relevance of Induced Pluripotent Stem Cells for the Study of Physiological and Premature Aging
    1182. Turning Round: Optimizing the Anti-Inflammatory Properties of Equine Bone Marrow Derived Mesenchymal Stem Cells for Osteoarthritis Through Three-Dimensional …
    1183. Immunomodulatory properties and senescence-associated secretory phenotypes in human mesenchymal stem cell aging
    1184. Potency of Human Cardiosphere‐Derived Cells from Patients with Ischemic Heart Disease Is Associated with Robust Vascular Supportive Ability
    1185. Stem cells, scaffolds and small molecules for orthopedic tissue regeneration
    1186. Cardiac Effects of Antirheumatic Drugs
    1187. C. Elegans Eats Its Own Intestine to Make Yolk: A Cause of Senescent Polymorbidity
    1188. Senescence Induced by DNA Demethylating Drugs to Treat Solid Tumors
    1189. Autophagy-dependent gut-to-yolk biomass conversion generates visceral polymorbidity in aging C. elegans
    1190. Identification of Molecular Determinants of Cellular Senescence in Cancer and Aging
    1191. as a model for aging research
    1192. Old maids: aging and its impact on microglia function
    1193. Key Age-Imposed Signaling Changes That Are Responsible for the Decline of Stem Cell Function
    1194. The effect of metformin on absolute telomere length
    1195. The role of melatonin, a multitasking molecule, in retarding the processes of ageing
    1196. Chromatin architectural changes during cellular senescence and aging
    1197. Nuclear translocation of argonaute 2 in cytokine-induced senescence
    1198. Inflammation and CMV-associated lymphocyte senescence in chronic HIV infection
    1199. Length-independent telomere damage drives cardiomyocyte senescence
    1200. VRK1 phosphorylates Tip60 acetyltransferase and promotes its accumulation in response to both DNA damage and mitogens
    1201. Induced Cell Turnover: A Novel Therapeutic Modality for In Situ Tissue Regeneration
    1202. Induction de la sénescence endothéliale auriculaire par l’angiotensine II et la thrombine: rôle du stress oxydant et caractérisation du phénotype pro-thrombotique, pro …
    1203. Gestational chronodisruption leads to persistent changes in the rat fetal and adult adrenal clock and function
    1204. Induction of atrial endothelial senescence by angiotensin II and thrombin: role of oxidative stress and characterization of pro-thrombotic, pro-adhesive, proteolytic and …
    1205. Induction of iPS Cell Differentiation Into Connexin26 Positive Cells with Gap Junction Plaques and Characterization of Cochlear Feeder Cell
    1206. AGE-ASSOCIATED LAMIN-B1 REDUCTION IN THE THYMIC EPITHELIAL CELLS AND ITS ROLE IN THYMIC INVOLUTION
    1207. The role of epigenetics in renal ageing
    1208. Cancer and aging-the inflammatory connection
    1209. The role of melanocyte senescence in skin ageing
    1210. Restoring the quantity and quality of elderly human mesenchymal stem cells for autologous cell-based therapies
    1211. Regulation of the Pro-Tumorigenic Senescence-Associated Secretory Phenotype
    1212. LE POTENTIEL HEPATIQUE DES CELLULES SOUCHES MESENCHYMATEUSES RAJEUNNIES ET DES PROGENITEURS ENDODERMIQUES: CONTRIBUTION …
    1213. Different transcriptional profiling between senescent and non-senescent human coronary artery endothelial cells (HCAECs) by omeprazole and lansoprazole …
    1214. Adoptive autophagy activation: a much-needed remedy against chemical induced neurotoxicity/developmental neurotoxicity
    1215. Aging and Antiaging Strategies
    1216. Comparison of mesenchymal stem cells obtained by suspended culture of synovium from patients with rheumatoid arthritis and osteoarthritis
    1217. Antiretroviral Drug Mediated Astrocyte Senescence as a Contributor to HIV-1-Associated Neurocognitive Disorders
    1218. Senescent Cells Drive Frailty through Systemic Signals
    1219. Changes in the biochemical taste of cytoplasmic and cell-free DNA are major fuels for inflamm-aging
    1220. The association between back muscle characteristics and pressure pain sensitivity in low back pain patients
    1221. Role of pattern recognition receptors of the neurovascular unit in inflamm-aging
    1222. Hepatic potential of Reversed-age Mesenchymal Stem Cells and Endodermal Progenitors: Contribution of LGR5 and Cdc42 cell signaling pathways
    1223. Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis
    1224. Synthetic lethal treatment strategies for tumor cell senescence
    1225. ISEV2018 abstract book
    1226. Aging, Cellular Senescence, and Kidney Fibrosis
    1227. Sex hormones and immunosenescence
    1228. Telomerase may paradoxically accelerate aging of the DNA methylome
    1229. CD36 initiates the secretory phenotype during the establishment of cellular senescence
    1230. A novel in vitro macrophage senescence model to study macrophaging
    1231. A novel in vitro macrophage senescence model to study macrophaging
    1232. Ageing Astrocytes-Implications for Motoneuron Dysfunction and Sarcopenia
    1233. BMP-7: role and regulation in osteoarthritis
    1234. Aging and Malignant Hemopathies: A Complex Multistep Process
    1235. Biomarkers for Identification of the Dormancy Phenotypes Senescence and Quiescence in Malignancy
    1236. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) and liver fibrosis: A review
    1237. Modulating Ageing Anti-Ageing
    1238. An in vivo and in vitro study of stress-induced senescence in neurones and its role in neurodegeneration
    1239. Gene Expression, Epigenetics and Ageing
    1240. German Congress of Laboratory Medicine: 15th Annual Congress of the DGKL (German Society of Clinical Chemistry and Laboratory Medicine) and the 3rd …
    1241. Aging Mouse Models Reveal Complex Tumor-Microenvironment Interactions in Cancer Progression
    1242. The role of neutrophils in telomere induced senescence via bystander effects
    1243. MITOCHONDRIAL STRESS COMMUNICATION IN MAMMALIAN CELLS
    1244. GATA4-dependent regulation of the secretory phenotype via MCP-1 underlies lamin A-mediated human mesenchymal stem cell aging
    1245. Sirt1 and Parp1 as epigenome safeguards and microRNAs as SASP-associated signals, in cellular senescence and aging
    1246. Exosome-based immunomodulation during aging: a nano-perspective on inflamm-aging
    1247. Leukocyte count, systemic inflammation, and health status in older adults: a narrative review
    1248. Two Conserved Histone H3 Lys9 Demethalases KDM3A and KDM4C Regulate MSCs Senescence Progress
    1249. Nutrient Sensing, Signaling and Ageing: The Role of IGF-1 and mTOR in Ageing and Age-Related Disease
    1250. Identification of HSP90 inhibitors as a novel class of senolytics
    1251. Aging of the Bone
    1252. Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease
    1253. PREMATURE IMMUNOSENESCENCE IN WOMEN NEWLY DIAGNOSED WITH BREAST CANCER–ROLE OF EARLY-LIFE STRESS
    1254. Mitochondria-targeted hydrogen sulfide attenuates endothelial senescence by selective induction of splicing factors HNRNPD and SRSF2
    1255. Sex and the Aging Immune System
    1256. Molecular pathology: the roles of P53 in the oxidative stress and DNA damage responses in chronic liver disease and hepatocellular carcinoma
    1257. A Computational System for Automated Meta-Analysis of Gene Expression Data
    1258. Modulating Aged Macrophages and Osteoprogenitors with a Calcium Phosphate Drug Delivery System
    1259. Examining Autophagy and Mitophagy as Inducible Mechanisms of Cellular Remodelling
    1260. Proteotoxicity links therapy-induced cancer cell senescence to Alzheimer’s disease
    1261. Macrophages in M1/M2 states and exposed to amyloid-beta: a RNA-seq analysis in human cells
    1262. Atorvastatin inhibits inflammatory response, attenuates lipid deposition, and improves the stability of vulnerable atherosclerotic plaques by modulating …
    1263. Werner Syndrome as a Model of Human Aging
    1264. Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and aging
    1265. Cytokine profile of breast cell lines after different radiation doses
    1266. Exercise and circulating factors associated with skeletal muscle and bone health in older age
    1267. Microbiota, NASH, HCC and the potential role of probiotics
    1268. Autophagy and Signaling
    1269. β-Hydroxybutyrate prevents vascular senescence through hnRNP A1-mediated upregulation of Oct4
    1270. Sarcopenia: aging-related loss of muscle mass and function
    1271. Zinc finger protein ZFP36L1 promotes osteoblastic differentiation but represses adipogenic differentiation of mouse multipotent cells
    1272. Elucidating the role of metabolic changes in modulating cell fate following treatment with anti-mitotic drugs
    1273. TGF-β signaling accelerates senescence of human bone-derived CD271 and SSEA-4 double-positive mesenchymal stromal cells
    1274. Progenitor cells from the adult heart
    1275. A rising star in pancreatic diseases: pancreatic stellate cells
    1276. Secretome analysis of testicular peritubular cells as a clue for solving the puzzle of the human spermatogonial stem cell niche
    1277. Functional Identification of MicroRNAs Counteracting Cellular Senescence
    1278. The Geriatrician’s Perspective on Surgery in the Geriatric Population
    1279. Senescence of bone marrow-derived mesenchymal stem cells from patients with idiopathic pulmonary fibrosis
    1280. The Long Noncoding RNA H19 Controls Endothelial Cell Functions by STAT3 Repression
    1281. Clinical Implications for Mitochondrial Stress Induced Senescence and Potential InterventionsS
    1282. The effects of aging in the hippocampus and cognitive decline
    1283. Human Cytomegalovirus as a driving force towards Immunosenescence
    1284. Hematopoietic Stem Cell Aging and Malignant Hemopathies
    1285. Role of Autophagy in Liver Regeneration
    1286. Old age causes de novo intracortical bone remodeling and porosity in mice
    1287. Aging Kidney and Aging-Related Disease
    1288. Melatonin rescued interleukin 1β-impaired chondrogenesis of human mesenchymal stem cells
    1289. Senescence-associated IL-6 and IL-8 cytokines induce a self-and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in …
    1290. Model of Chaperones in Aging
    1291. Senescent Cells Differentially Translate Senescence-Related mRNAs Via Ribosome Heterogeneity
    1292. Accumulation of prelamin A drives inflammation in the heart with implications for treatment of inherited and acquired cardiomyopathies
    1293. Senescence in COPD and its comorbidities
    1294. Characterizing Senescence in Astrocytes and its Effect on Neurons
    1295. Barshop Symposium on Aging 2017 Abstracts
    1296. Role of vascular smooth muscle cell derived-exosomes in age-related vascular amyloidosis
    1297. Cancer metabolism in space and time: beyond the Warburg effect
    1298. Melatonin protected cardiac microvascular endothelial cells against oxidative stress injury via suppression of IP3R-[Ca2+]c/VDAC-[Ca2+]m axis by activation of …
    1299. Tumor Microenvironment, Therapeutic Resistance, and Personalized Medicine
    1300. Liver regeneration in aged mice: new insights
    1301. In medio stat virtus: unanticipated consequences of telomere dysequilibrium
    1302. The contribution of oxidative stress and inflamm-aging in human and equine asthma
    1303. NR4A1 promotes diabetic nephropathy by activating mff-mediated mitochondrial fission and suppressing parkin-mediated mitophagy
    1304. DNA damage induced by Strontium-90 exposure at low concentrations in mesenchymal stromal cells: the functional consequences
    1305. Cardiac ageing: extrinsic and intrinsic factors in cellular renewal and senescence
    1306. Role of primary cilia in non-dividing and post-mitotic cells
    1307. The role of cancer-associated fibroblasts and fibrosis in liver cancer
    1308. Reversibility of chemotherapy-induced senescence is independent of autophagy and a potential model for tumor dormancy and cancer recurrence.
    1309. Cancer Cells Exploit Notch Signaling To Redefine A Tumor Supportive Cytokine Milieu
    1310. Programmed cell senescence in skeleton during late puberty
    1311. Metabolic reprogramming for cancer cells and their microenvironment: Beyond the Warburg Effect
    1312. SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy
    1313. Psychological stress and mitochondria: a conceptual framework
    1314. Immunosenescence and hurdles in the clinical management of older HIV-patients
    1315. Stress granules counteract senescence by sequestration of PAI‐1
    1316. The power behind the throne: senescence and the hallmarks of cancer
    1317. The exercise and diet-microbiome paradigm: influences of physical activity and dietary nutrition on the human gut microbiome
    1318. Empagliflozin rescues diabetic myocardial microvascular injury via AMPK-mediated inhibition of mitochondrial fission
    1319. The functions and regulation of the PTEN tumour suppressor: new modes and prospects
    1320. Distribution and molecular characterization of South African Bacillus Anthracis strains and their associated bacteriophages
    1321. TARGETING ASCT2/SLC1A5 FOR INHIBITION OF CELLULAR GROWTH AND METABOLISM IN TRIPLE-NEGATIVE BREAST CANCER
    1322. Cellular Senescence and Inflammaging in Age-Related Diseases
    1323. The gut microbiome and liver cancer: mechanisms and clinical translation
    1324. BBA-Reviews on Cancer
    1325. RNA Binding Proteins, Ageing and Caloric Restriction
    1326. Controlling senescence by PML and PML nuclear bodies
    1327. Ataxia telangiectasia syndrome: moonlighting ATM
    1328. ER stress and impaired autophagy flux in neuronal degeneration and brain injury
    1329. Leukotriene D4 induces cellular senescence in osteoblasts
    1330. Understanding the Basis of Gene Regulation of Common Complex Diseases by Computational Analysis of Next-generation Sequencing Data
    1331. Matrix stiffness regulates oxidative stress response of human dermal fibroblasts
    1332. Inflammation and the Gut-Liver Axis in the Pathophysiology of Cholangiopathies
    1333. Dendritic Polyglycerol Sulfate Hydrogels as a Potential Viscosupplement for Treatment of Osteoarthritis
    1334. Bile acids and cancer: direct and environmental-dependent effects
    1335. INVOSSATM–a cell and gene therapy for osteoarthritis
    1336. In vitro proinflammatory gene expression predicts in vivo telomere shortening: A preliminary study
    1337. Enhancer function driving cellular senescence, DNA damage repair, differentiation, and nuclear organization
    1338. Investigating strategies to boost cutaneous varicella zoster virus-specific immune responses in ageing humans
    1339. Natural variations in yeast aging reveal genetic and environmental factors
    1340. Circulating levels of soluble Receptor for Advanced Glycation End-products (sRAGE) decrease with aging and may predict age-related cardiac remodeling
    1341. Age-associated metabolic reprogramming, oxidative stress response, and cancer progression
    1342. Impact of age-associated estrogen deficiency on innate immune responses to myocardial ischemic injury in the female rat heart
    1343. Antioxidant and oxidative stress: A mutual interplay in age-related diseases
    1344. MicroRNAs deregulation in prostate cancer
    1345. Vaccination in the elderly: The challenge of immune changes with aging
    1346. From rapalogs to anti-aging formula
    1347. Biomarkers of monitoring and functional reserve of physiological systems over time in HIV: expert opinions for effective secondary prevention
    1348. IDENTIFICATION OF INTRINSIC REGULATORS IN NORMAL AND MALIGNANT HUMAN HEMATOPOIESIS
    1349. Epigenome-wide DNA methylation and mitochondrial DNA content in relation to in utero PM2.5 exposure
    1350. l-Carnitine inhibits the senescence-associated secretory phenotype of aging adipose tissue by JNK/p53 pathway
    1351. adipose tissue, aging, and metabolism
    1352. Growth hormone impact on adipose tissue and aging
    1353. adipose tissue Quality in Aging: How Structural and Functional Aspects of adipose tissue Impact Skeletal Muscle Quality
    1354. Targeting senescent cells alleviates obesity‐induced metabolic dysfunction
    1355. adipose tissue: A Tertiary Lymphoid Organ: Does It Change with Age?
    1356. Age-Dependent and-Independent Effects of Perivascular adipose tissue and Its Paracrine Activities during Neointima Formation
    1357. Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
    1358. Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia
    1359. Heparanase upregulation from adipocyte associates with inflammation and endothelial injury in diabetic condition
    1360. Cellular senescence: at the nexus between ageing and diabetes
    1361. OBESITY INDUCES MESENCHYMAL STEM CELL SENESCENCE AND DYSFUNCTION
    1362. Histologic analysis and lipid profiling reveal reproductive age-associated changes in peri-ovarian adipose tissue
    1363. In vitro model of chronological aging of adipocytes: Interrelationships with hypoxia and oxidation
    1364. Sympathetic nervous system as a target for aging and obesity-related cardiovascular diseases
    1365. Senescent cells in the development of cardiometabolic disease
    1366. Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression
    1367. Relationship between Circulating Protein p53 and High Sensitivity C-Reactive Protein in Central Obesity Men with Inflammaging
    1368. Extracellular fraction of adipose tissue as an innovative regenerative approach for vitiligo treatment
    1369. Normal breast tissue at risk for cancer development: A breast cancer initiating role for mammary adipocytes
    1370. Age-associated inflammation alters the aging trajectory
    1371. Life-span Extension Drug Interventions Affect adipose tissue Inflammation in Aging
    1372. Cellular senescence and senescence‐associated T cells as a potential therapeutic target
    1373. Mitochondrial Uncoupling Protein-2 Is a Putative Link Between Mitochondrial Dysfunction and Fibroblast Senescence in Age-Related Lung Fibrosis
    1374. Lipotoxicity, aging, and muscle contractility: does fiber type matter?
    1375. Skeletal muscle as potential central link between sarcopenia and immune senescence
    1376. Ileal Transposition Increases Pancreatic β Cell Mass and Decreases β Cell Senescence in Diet-Induced Obese Rats
    1377. ALCAT1 Deficiency Attenuates Obesity Induced Cellular Senescence in P16-3MR Transgenic Mice
    1378. Short exposure to cold atmospheric plasma induces senescence in human skin fibroblasts and adipose mesenchymal stromal cells
    1379. Recent advances in understanding tumor stroma-mediated chemoresistance in breast cancer
    1380. Alteration of Hypoxia-Associated Gene Expression in Replicatively Senescent Mesenchymal Stromal Cells under Physiological Oxygen Level
    1381. Rejuvenating Strategies of Tissue-specific Stem Cells for Healthy Aging
    1382. Novel contributors and mechanisms of cellular senescence in hypertension-associated premature vascular aging
    1383. β Cell Senescence as a Common Contributor to Type 1 and Type 2 Diabetes
    1384. Obesity and cancer: A mechanistic overview of metabolic changes in obesity that impact genetic instability
    1385. Age-dependent impairment of adipose-derived stem cells isolated from horses
    1386. Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity?
    1387. Therapeutic Irradiation: Consequences for Bone and Bone Marrow Adipose
    1388. The Role of the Gut Microbiome and its Derived Mediators in Nonalcoholic Fatty Liver Disease
    1389. Inflamm-Aging Is Associated with Lower Plasma PTX3 Concentrations and an Impaired Capacity of PBMCs to Express hTERT following LPS Stimulation
    1390. Impaired immunomodulatory ability of type 2 diabetic adipose-derived mesenchymal stem cells in regulation of inflammatory condition in mixed leukocyte …
    1391. 3D printing breast tissue models: A review of past work and directions for future work
    1392. Aged‐senescent cells contribute to impaired heart regeneration
    1393. Chemotherapy-induced cellular senescence suppresses progression of Notch-driven T-ALL
    1394. Senescent cells: A new Achilles’ heel to exploit for cancer medicine?
    1395. The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD+ decline
    1396. Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing
    1397. The burden of metabolic syndrome on osteoarthritic joints
    1398. Modulation of senoinflammation by calorie restriction based on biochemical and Omics big data analysis
    1399. Remodeling the Microenvironment before Occurrence and Metastasis of Cancer
    1400. Immune senescence and cardiomyopathy associated with obesity
    1401. The role of cellular senescence in diabetes mellitus and osteoporosis: molecular pathways and potential interventions
    1402. Filamin B and CD13 Are Components of Senescent Secretomes That May Be Involved in Primary (Stress Induced) and Paracrine Senescence of Mesenchymal …
    1403. and Ahmet Turan Isik
    1404. β‐Cell senescence in the pathogenesis of type 2 diabetes
    1405. Inflammation, Frailty and Cardiovascular Disease
    1406. Cellular Senescence in the Kidney
    1407. Heat shock response to exercise in pancreatic islets of obese mice
    1408. Regulation of senescence and the SASP
    1409. The Links Between Osteoporosis and Sarcopenia in Women
    1410. Increased renal cellular senescence in murine high-fat diet: effect of the senolytic drug quercetin
    1411. Type 2 diabetes is associated with the accumulation of senescent T cells
    1412. Elimination of senescent osteoclast progenitors has no effect on the age‐associated loss of bone mass in mice
    1413. Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38+ pro-inflammatory macrophages
    1414. Adipokines: New Therapeutic Target for Osteoarthritis?
    1415. Major depression and enhanced molecular senescence abnormalities in young and middle-aged adults
    1416. Expansion and cell-cycle arrest: Common denominators of cellular senescence
    1417. Mechanisms of obesity-induced metabolic and vascular dysfunctions
    1418. Redefining Chronic Inflammation in Aging and Age-Related Diseases: Proposal of the Senoinflammation Concept
    1419. Mixing old and young: enhancing rejuvenation and accelerating aging
    1420. Involvement of adiponectin in age-related increases in tear production in mice
    1421. LPS-induced premature osteocyte senescence: Implications in inflammatory alveolar bone loss and periodontal disease pathogenesis
    1422. Emerging roles of and therapeutic strategies targeting BRD4 in cancer
    1423. In situ evidence of cellular senescence in Thymic Epithelial Cells (TECs) during human thymic involution
    1424. Cellular senescence in bone
    1425. Effect of aging on behaviour of mesenchymal stem cells
    1426. Earlier changes in mice after D-galactose treatment were improved by mitochondria derived small peptide MOTS-c
    1427. Pleiotropic effect of fibrates on senescence and autophagy in osteoarthritis
    1428. Low-dose quercetin positively regulates mouse healthspan
    1429. Microbial metabolites in non-alcoholic fatty liver disease
    1430. Elevated Local Senescence in Diabetic Wound Healing Is Linked to Pathological Repair via CXCR2
    1431. The potential role of senescence in limiting fibrosis caused by aging
    1432. Metabolic Alterations in Aging Macrophages: Ingredients for Inflammaging?
    1433. Protective role of polyphenols against vascular inflammation, aging and cardiovascular disease
    1434. TGF-β Signaling in Cellular Senescence and Aging-Related Pathology
    1435. Obesity-induced cellular senescence drives anxiety and impairs neurogenesis
    1436. Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells
    1437. Targeting normal and cancer senescent cells as a strategy of senotherapy
    1438. Senescent and apoptotic osteocytes and aging: Exercise to the rescue?
    1439. Senotherapeutics: Emerging strategy for healthy aging and age-related disease
    1440. Extracellular vesicles circulating in young organisms promote healthy longevity
    1441. Effectiveness of stage by stage bariatric interventions for regression of comorbidity at obese class III patients
    1442. L1 drives IFN in senescent cells and promotes age-associated inflammation
    1443. The STATus of STAT3 in Lung Cell Senescence?
    1444. Intraarticular senescent chondrocytes impair the cartilage regeneration capacity of mesenchymal stem cells
    1445. Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix‐related gene expression partly via secretion of complement factor D
    1446. Mitochondria and cellular senescence: Implications for musculoskeletal ageing
    1447. Age and Frailty as Risk Factors for the Development of Osteoarthritis
    1448. The biology of frailty in humans and animals: Understanding frailty and promoting translation
    1449. Turning back time with emerging rejuvenation strategies
    1450. Senescence and senotherapeutics: A new field in cancer therapy
    1451. Senescence marker activin A is increased in human diabetic kidney disease: association with kidney function and potential implications for therapy
    1452. The Safe and Efficacious Use of Secretome From Fibroblasts and Adipose-derived (but not Bone Marrow-derived) Mesenchymal Stem Cells for Skin …
    1453. Cellular Senescence and the Immune System in Cancer
    1454. Advanced liver steatosis accompanies an increase in hepatic inflammation, colonic, secondary bile acids and Lactobacillaceae/Lachnospiraceae bacteria in C57BL/6 …
    1455. KRAS, YAP, and obesity in pancreatic cancer: A signaling network with multiple loops
    1456. Chronic inflammation in the etiology of disease across the life span
    1457. Pan-senescence transcriptome analysis identified RRAD as a marker and negative regulator of cellular senescence
    1458. Flavonoids: Broad Spectrum Agents on Chronic Inflammation
    1459. Astrocyte senescence in an Alzheimer’s disease mouse model is mediated by TGF-β1 and results in neurotoxicity
    1460. mTOR as a central regulator of lifespan and aging
    1461. Vascular Diseases and Gangliosides
    1462. Muscle-derived miR-34a increases with age in circulating extracellular vesicles and induces senescence of bone marrow stem cells
    1463. Aging and lineage allocation changes of bone marrow skeletal (stromal) stem cells
    1464. Looking for immortality: Review of phytotherapy for stem cell senescence
    1465. Gangliosides Contribute to Vascular Insulin Resistance
    1466. Emerging senolytic agents derived from natural products
    1467. Vitamin E: Regulatory Role on Signal Transduction
    1468. Experimental strategies of mesenchymal stem cell propagation: Adverse events and potential risk of functional changes
    1469. Introductory Chapter: Nonalcoholic Fatty Liver Disease-What Should We Know?
    1470. The role of probiotics in nonalcoholic fatty liver disease: a new insight into therapeutic strategies
    1471. Cellular senescence and chronological age in various human tissues: A systematic review and meta‐analysis
    1472. Nrf2 exerts mixed inflammation and glucose metabolism regulatory effects on murine RAW264. 7 macrophages
    1473. Chronic Low-grade Inflammatory Phenotype (CLIP) and Senescent Immune Dysregulation
    1474. Obesity May Accelerate the Aging Process
    1475. Manufacturing of primed mesenchymal stromal cells for therapy
    1476. Pyrroloquinoline quinone prevents estrogen deficiency-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence
    1477. Obesity is a common soil for premature cardiac aging and heart diseases-role of autophagy
    1478. Culinary medicine: advancing a framework for healthier eating to improve chronic disease management and prevention
    1479. Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development
    1480. Senescence in the lung: is this getting old?
    1481. TGF-β mediates aortic smooth muscle cell senescence in Marfan syndrome
    1482. Cellular senescence in cardiac diseases
    1483. Bone marrow niches for skeletal progenitor cells and their inhabitants in health and disease
    1484. Potential role of senescence in radiation-induced damage of the aged skeleton
    1485. The kynurenine pathway: a finger in every pie
    1486. Cell aging and cellular senescence in skin aging—Recent advances in fibroblast and keratinocyte biology
    1487. The Senescent Cell, SC
    1488. Mitochondria-driven elimination of cancer and senescent cells
    1489. Use of MSCs in Antiaging Strategies
    1490. Dynamic role of the codon 72 p53 single-nucleotide polymorphism in mammary tumorigenesis in a humanized mouse model
    1491. Promotion and induction of liver cancer by gut microbiome-mediated modulation of bile acids
    1492. Cellular cross-talks in the diseased and aging heart
    1493. Conditioned Medium of Mesenchymal Stromal Cells: A New Class of Therapeutics
    1494. Coexisting frailty with heart failure
    1495. Barshop Symposium on Aging 2018 Abstracts
    1496. Amitosenescence and Pseudomitosenescence: Putative New Players in the Aging Process
    1497. HIF1α‐mediated AIMP3 suppression delays stem cell aging via the induction of autophagy
    1498. Inflammaging as a common ground for the development and maintenance of sarcopenia, obesity, cardiomyopathy and dysbiosis
    1499. Inflammation: a common contributor to cancer, aging, and cardiovascular diseases—expanding the concept of cardio-oncology
    1500. Inflammation as a mediator of arterial ageing
    1501. LINE-1 derepression in senescent cells triggers interferon and inflammaging
    1502. Cells exhibiting strong p16INK4a promoter activation in vivo display features of senescence
    1503. Early vascular ageing and cellular senescence in chronic kidney disease
    1504. Childhood obesity and leucocyte telomere length
    1505. Cell-Free Culture Supernatant of Probiotic Lactobacillus fermentum Protects Against H2O2-Induced Premature Senescence by Suppressing ROS-Akt-mTOR Axis in …
    1506. Raman fingerprints as promising markers of cellular senescence and aging
    1507. Where Metabolism Meets Senescence: Focus on Endothelial Cells
    1508. Exercise Training for the Elderly: Inflammaging and the Central Role for HSP70
    1509. Proteomic analysis of human mesenchymal stromal cell secretomes: a systematic comparison of the angiogenic potential
    1510. BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome
    1511. Quantifying Senescence-Associated Phenotypes in Primary Multipotent Mesenchymal Stromal Cell Cultures
    1512. Roles of JAK2 in aging, inflammation, hematopoiesis and malignant transformation
    1513. Independent Roles of Estrogen Deficiency and Cellular Senescence in the Pathogenesis of Osteoporosis: Evidence in Young Adult Mice and Older Humans
    1514. Cellular senescence in arterial diseases
    1515. 25-Hydroxyvitamin D3 positively regulates periodontal inflammaging via SOCS3/STAT signaling in diabetic mice
    1516. Inflammation, Infection and Atherosclerosis
    1517. Obesity-Associated Hypermetabolism and Accelerated Senescence of Bone Marrow Stromal Stem Cells Suggest a Potential Mechanism for Bone Fragility
    1518. Chronic whole-body heat treatment relieves atherosclerotic lesions, cardiovascular and metabolic abnormalities, and enhances survival time restoring the anti …
    1519. The chemistry of senescence
    1520. Stem Cell Senescence: the Obstacle of the Treatment of Degenerative Disk Disease
    1521. Autophagy Dysfunction, Cellular Senescence, and Abnormal Immune-Inflammatory Responses in AMD: From Mechanisms to Therapeutic Potential
    1522. Breast tissue biology expands the possibilities for prevention of age-related breast cancers
    1523. Senescent cell clearance by the immune system: Emerging therapeutic opportunities
    1524. Metformin and Aging: A Review
    1525. Non-Alcoholic Fatty Liver Disease, and the Underlying Altered Fatty Acid Metabolism, Reveals Brain Hypoperfusion and Contributes to the Cognitive Decline in APP …
    1526. Senile Osteoporosis: The Involvement of Differentiation and Senescence of Bone Marrow Stromal Cells
    1527. Muscle and Bone Biology–Similarities and Differences
    1528. COPD as a Disease of Immunosenescence
    1529. Sex hormones and anticancer immunity
    1530. Targeting chronic innate inflammatory pathways, the main road to prevention of osteoarthritis progression
    1531. Autofluorescence is a Reliable in vitro Marker of Cellular Senescence in Human Mesenchymal Stromal Cells
    1532. Methionine restriction delays senescence and suppresses the senescence-associated secretory phenotype in the kidney through endogenous hydrogen sulfide
    1533. Identification of Aberrantly Expressed Genes during Aging in Rat Nucleus Pulposus Cells
    1534. Role of the Gut–Liver Axis in Liver Inflammation, Fibrosis, and Cancer: A Special Focus on the Gut Microbiota Relationship
    1535. Type 2 diabetes: how much of an autoimmune disease?
    1536. Urine-Derived Stem Cells Secreting Small Extracellular Vesicles Loaded in Acellular Amniotic Membrane for Wound Healing Promotion in Aged Mice
    1537. Type 2 Diabetes: How Much of an Autoimmune Disease?
    1538. Fasting and rapamycin: diabetes versus benevolent glucose intolerance
    1539. Roles of the Immune System in the Development and Progression of Hepatocellular Carcinoma
    1540. Genetic Stability of Mesenchymal Stromal Cells for Regenerative Medicine Applications: A Fundamental Biosafety Aspect
    1541. Regulation of cellular senescence by retinoid X receptors and their partners
    1542. Secretome of Mesenchymal Stem Cells and its Impact on Chronic Obstructive Pulmonary Disease
    1543. Defective induction of the proteasome associated with T‐cell receptor signaling underlies T‐cell senescence
    1544. Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
    1545. When the skin is in the center of interest-An aging issue
    1546. New frontiers in osteoporosis therapy
    1547. Aging and Cardiovascular Diseases: The Role of Cellular Senescence
    1548. Oxidative Stress and Non-Alcoholic Fatty Liver Disease: Effects of Omega-3 Fatty Acid Supplementation
    1549. Efficacy of 3D Culture Priming is Maintained in Human Mesenchymal Stem Cells after Extensive Expansion of the Cells
    1550. Potential Mechanisms of 3, 4-Oxo-Isopropylidene-Shikimic Acid in Ameliorating 2, 4, 6-Trinitrobenzenesulfonic Acid-Induced Colitis in Rats
    1551. Principal Criteria for Evaluating the Quality, Safety and Efficacy of hMSC-Based Products in Clinical Practice: Current Approaches and Challenges
    1552. The clinical impact and biological mechanisms of skeletal muscle aging
    1553. Chronic Kidney Disease and the Vascular Endothelium
    1554. Current Knowledge and New Challenges in Exercise Immunology
    1555. Aspirin ameliorates the long‐term adverse effects of doxorubicin through suppression of cellular senescence
    1556. Aging, Immunity, and Neuroinflammation: The Modulatory Potential of Nutrition
    1557. Perspectives of the International Society of Cell & Gene Therapy Gastrointestinal Scientific Committee on the Intravenous Use of Mesenchymal Stromal Cells in …
    1558. Cellular senescence: aging, cancer, and injury
    1559. Searching for the Holy Grail Will Need Biomarkers
    1560. DNA damage response manages cell cycle restriction of senile multipotent mesenchymal stromal cells
    1561. The role of mitochondria-derived peptides in cardiovascular disease: Recent updates
    1562. Tackling Aging by Using miRNA as a Target and a Tool
    1563. Selective elimination of senescent cells by mitochondrial targeting is regulated by ANT2
    1564. Premature aging and cancer development in transgenic mice lacking functional CYLD
    1565. Obesity-Induced Sympathoexcitation is Associated with Nrf2 Dysfunction in the Rostral VentroLateral Medulla
    1566. Senescence‐induced immunophenotype, gene expression and electrophysiology changes in human amniocytes
    1567. The senescence-associated secretory phenotype and its regulation
    1568. An early‐senescence state in aged mesenchymal stromal cells contributes to hematopoietic stem and progenitor cell clonogenic impairment through the activation of a …
    1569. Extracellular vesicles and redox modulation in aging
    1570. Survival of aging CD264+ and CD264− populations of human bone marrow mesenchymal stem cells is independent of colony‐forming efficiency
    1571. Seno-suppressive molecules as new therapeutic perspectives in rheumatic diseases
    1572. Identification of senescent cells in multipotent mesenchymal stromal cell cultures: current methods and future directions
    1573. The ING1a model of rapid cell senescence
    1574. The key players of tumor microenvironment and their role in breast cancer
    1575. Skin barrier immunity and ageing
    1576. Integration of heterogeneous functional genomics data in gerontology research to find genes and pathway underlying aging across species
    1577. Metabolic requirements of human pro-inflammatory B cells in aging and obesity
    1578. Aging and bone
    1579. Control of Inflammation by Calorie Restriction Mimetics: On the Crossroad of Autophagy and Mitochondria
    1580. PGC1α repression in IPF fibroblasts drives a pathologic metabolic, secretory and fibrogenic state
    1581. Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming☆
    1582. The Molecular Physiology of Ageing: New Targets for Regenerative Medicine
    1583. Knockdown of angiopoietin-like 2 induces clearance of vascular endothelial senescent cells by apoptosis, promotes endothelial repair and slows …
    1584. Obesity and Hepatocarcinogenesis
    1585. Lifestyle Choices, Psychological Stress and Their Impact on Ageing: The Role of Telomeres
    1586. Mechanisms of Calorie Restriction: A Review of Genes Required for the Life-Extending and Tumor-Inhibiting Effects of Calorie Restriction
    1587. Exosomes may be the potential new direction of research in osteoarthritis management
    1588. Mitochondrial protection partly mitigates kidney cellular senescence in swine atherosclerotic renal artery stenosis
    1589. Molecular insights into Hutchinson-Gilford progeria syndrome and age-associated disease: from mechanisms to treatment strategy
    1590. Rapid detection of senescent mesenchymal stromal cells by a fluorescent probe
    1591. Iron and iron-dependent reactive oxygen species in the regulation of macrophages and fibroblasts in non-healing chronic wounds
    1592. Low‐Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro
    1593. Maternal Sleep in Pregnancy and Postpartum Part II: Biomechanisms and Intervention Strategies
    1594. Hydroxyurea‐induced Senescent Peripheral Blood Mesenchymal Stromal Cells Inhibit Bystander Cell Proliferation of JAK2V617F‐positive Human Erythroleukemia …
    1595. Doxorubicin and liposomal doxorubicin induce senescence by enhancing nuclear factor kappa B and mitochondrial membrane potential
    1596. The Upregulation of Toll-Like Receptor 3 via Autocrine IFN-β Signaling Drives the Senescence of Human Umbilical Cord Blood-Derived Mesenchymal Stem …
    1597. Myeloid-derived suppressor cells: not only in tumor immunity
    1598. Moderate hyperoxia induces senescence in developing human lung fibroblasts
    1599. Senolytics and senostatics as adjuvant tumour therapy
    1600. The link between endometrial stromal cell senescence and decidualization in female fertility: the art of balance
    1601. Melatonin attenuates renal fibrosis in diabetic mice by activating the AMPK/PGC1α signaling pathway and rescuing mitochondrial function
    1602. Molecular taxonomy of osteoarthritis for patient stratification, disease management and drug development: biochemical markers associated with emerging clinical …
    1603. Differential Expression of Human N-Alpha-Acetyltransferase 40 (hNAA40), Nicotinamide Phosphoribosyltransferase (NAMPT) and Sirtuin-1 (SIRT-1) Pathway …
    1604. Regulation of inflammation as an anti‐aging intervention
    1605. Aiding and Abetting: How the Tumor Microenvironment Protects Cancer from Chemotherapy
    1606. Relationships between ion channels, mitochondrial functions and inflammation in human aging
    1607. Targeting senescent cells in translational medicine
    1608. Recent insights into the multiple pathways driving nonalcoholic steatohepatitis-derived hepatocellular carcinoma
    1609. Aging, sex, inflammation, frailty, and CMV and HIV Infections
    1610. Low-grade inflammation causes gap junction-coupled cell dysfunction throughout the body, which can lead to the spread of systemic inflammation
    1611. The upregulation of Toll-like receptor 3 via autocrine IFN-beta signaling drives the senescence of human mesenchymal stem cells through JAK1
    1612. Pak2 kinase promotes cellular senescence and organismal aging
    1613. Molecular Pathogenesis of Oral Submucous Fibrosis: A Critical Appraisal
    1614. Mechanisms of aging and potential role of selected polyphenols in extending healthspan
    1615. The role of lipids in aging-related metabolic changes
    1616. Emerging Role of Stem cell-derived Extravesicular MicroRNAs in Age-associated Human Diseases and in Different Therapies of Longevity
    1617. The genetics of human ageing
    1618. Inflammation in osteoarthritis: is it time to dampen the alarm (in) in this debilitating disease?
    1619. Estrogen deprivation triggers an immunosuppressive phenotype in breast cancer cells
    1620. Liver and Steroid Hormones—Can a Touch of p53 Make a Difference?
    1621. Impacts of the late adulthood diet-induced obesity onset on behavior, immune function, redox state and life span of male and female mice
    1622. The Mediterranean Diet Slows Down the Progression of Aging and Helps to Prevent the Onset of Frailty: A Narrative Review
    1623. Exosome: Advanced Development and a Novel Therapeutic Strategy for Osteoarthritis and Cartilage Injury
    1624. Diabetes drugs in the fight against Alzheimer’s disease
    1625. Patient-Derived Organoids from Human Bile: An In Vitro Method to Study Cholangiopathies
    1626. The Aging Thyroid: A Reappraisal Within the Geroscience Integrated Perspective
    1627. Immune Modulation by Transplanted Calcium Phosphate Biomaterials and Human Mesenchymal Stromal Cells in Bone Regeneration
    1628. Bone marrow-derived mesenchymal stem cells in three-dimensional co-culture attenuate degeneration of nucleus pulposus cells
    1629. Roles of sleep deprivation in cardiovascular dysfunctions
    1630. micro (RNA)-managing muscle wasting
    1631. Stem cell derived exosomes: microRNA therapy for age-related musculoskeletal disorders
    1632. Astrocyte senescence: Evidence and significance
    1633. FGF21 Mediates Mesenchymal Stem Cell Senescence via Regulation of Mitochondrial Dynamics
    1634. Aging and the Biological Response to Liver Injury
    1635. Age-Related Thymic Atrophy: Mechanisms and Outcomes
    1636. The Effects of Early-Life Drug and Dietary Interventions on Late-Life Disease Development
    1637. Preclinical Evidence for the Role of Stem/Stromal Cells in COPD
    1638. Melatonin attenuates myocardial ischemia‐reperfusion injury via improving mitochondrial fusion/mitophagy and activating the AMPK‐OPA1 signaling pathways
    1639. Therapeutic effect of n-butanol fraction of Huang-lian-Jie-du Decoction on ulcerative colitis and its regulation on intestinal flora in colitis mice
    1640. Future Cell and Gene Therapy for Osteoarthritis (OA): Potential for Using Mammalian Protein Production Platforms, Irradiated and Transfected Protein …
    1641. Gut microbiota in liver disease: too much is harmful, nothing at all is not helpful either
    1642. Embryonic stem cell-derived extracellular vesicles enhance the therapeutic effect of mesenchymal stem cells
    1643. Tumor microenvironment-driven non-cell-autonomous resistance to antineoplastic treatment
    1644. Pharmacology of metformin–An update
    1645. Restoring mechano-adaptation in aged murine bone
    1646. Slowing Down Ageing: The Role of Nutrients and Microbiota in Modulation of the Epigenome
    1647. Integrating cellular senescence with the concept of damage accumulation in aging: Relevance for clearance of senescent cells
    1648. Mechanistic complexities of bone loss in Alzheimer’s disease: a review
    1649. Investigation on Spectrum-Effect Correlation between Constituents Absorbed into Blood and Bioactivities of Baizhu Shaoyao San before and after Processing on …
    1650. Lifelong aerobic exercise protects against inflammaging and cancer
    1651. Distinct effects of epirubicin, cisplatin and cyclophosphamide on ovarian somatic cells of prepuberal ovaries
    1652. The Emerging Role of Exosomal Non-coding RNAs in Musculoskeletal Diseases
    1653. Mitochondria in the signaling pathways that control longevity and health span
    1654. Crosstalk between P53 and DNA Damage Response in Ageing
    1655. Diabetic gut microbiota dysbiosis as an inflammaging and immunosenescence condition that fosters progression of retinopathy and nephropathy
    1656. Dual faced HMGB1 plays multiple roles in cardiomyocyte senescence and cardiac inflammatory injury
    1657. Melatonin and chromatin
    1658. Mst1 facilitates hyperglycemia-induced retinal pigmented epithelial cell apoptosis by evoking mitochondrial stress and activating the Smad2 signaling pathway
    1659. Circular RNA CircCCNB1 sponges micro RNA-449a to inhibit cellular senescence by targeting CCNE2
    1660. Failure of immunosurveillance accelerates aging
    1661. Rationally-based therapeutic disease modification in systemic sclerosis: Novel strategies
    1662. Extracellular vesicles in human skin: cross-talk from senescent fibroblasts to keratinocytes by miRNAs
    1663. Pharmacodynamics OF TNF α inhibitors for the treatment of psoriasis
    1664. Integrated Theories of Biological Aging
    1665. Organismal Aging and Oxidants Beyond Macromolecules Damage<? Qry msg=” Please provide author biographies for up to three authors (each biography not …
    1666. The Role of Curcumin in the Modulation of Ageing
    1667. The Impending Epidemic of Cardiovascular Diseases in Patients With Cancer in Japan
    1668. Pro-and anti-tumorigenic functions of the senescence-associated secretory phenotype
    1669. Silencing of long noncoding RNA HOXA11-AS inhibits the Wnt signaling pathway via the upregulation of HOXA11 and thereby inhibits the proliferation …
    1670. Novel clinico-molecular insights into the role of bisphenol-A (BPA) in the etiology of diabetes
    1671. Mitochondria and aging—The role of exercise as a countermeasure
    1672. A novel form of Deleted in breast cancer 1 (DBC1) lacking the N-terminal domain does not bind SIRT1 and is dynamically regulated in vivo
    1673. INJURY SENESCENCE OF THE IMMUNE SYSTEM
    1674. Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and XIAP
    1675. Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons
    1676. Moving beyond the current limits of data analysis in longevity and healthy lifespan studies
    1677. Cellular senescence and the kidney: potential therapeutic targets and tools
    1678. The Biology of Senescence
    1679. The clock is ticking: the impact of ageing on T cell metabolism
    1680. Ribosomal DNA instability: an evolutionary conserved fuel for inflammaging
    1681. Role of microRNA-141 in the aging musculoskeletal system: a current overview
    1682. Activation of immunosuppressive network in the aging process
    1683. Senescence cell–associated extracellular vesicles serve as osteoarthritis disease and therapeutic markers
    1684. Molecular biology of acute and chronic inflammation
    1685. Transcriptomic analysis reveals the mechanism of sulfasalazine-induced liver injury in mice
    1686. Inflammatory bone marrow microenvironment
    1687. Cell and Gene Therapy for Spine Regeneration: Mammalian Protein Production Platforms for Overproduction of Therapeutic Proteins and Growth Factors
    1688. Interleukin-17 and senescence regulate the foreign body response
    1689. Nuclear-encoded Mitochondrial Genetic Variation in Human Aging and Longevity
    1690. Transient introduction of human telomerase mRNA improves hallmarks of progeria cells
    1691. DNA Damage Induced Cell Fates during Aging
    1692. Chromosomal instability and pro-inflammatory response in aging
    1693. Understanding the role of chondrocytes in osteoarthritis: utilizing proteomics
    1694. Emerging Roles of Complement Protein C1q in Neurodegeneration
    1695. Growth hormone in the tumor microenvironment
    1696. NAD+ Metabolism in Aging and Cancer
    1697. Cellular Stress and General Pathological Processes
    1698. A prospect of cell immortalization combined with matrix microenvironmental optimization strategy for tissue engineering and regeneration
    1699. The expression of P16 and S100 associated with elastin degradation and fibrosis of the Ligamentum Flavum hypertrophy
    1700. Risk Factors for Frailty and Cardiovascular Diseases: Are They the Same?
    1701. MicroRNAs in the Functional Defects of Skin Aging
    1702. Aging, Melatonin, and the Pro-and Anti-Inflammatory Networks
    1703. Huang-Lian-Jie-Du decoction ameliorates acute ulcerative colitis in mice via regulating NF-κB and Nrf2 signaling pathways and enhancing intestinal barrier function
    1704. Cellular senescence in cultured human brainstem astrocytes: Effect of oxidative stress
    1705. A murine aging cell atlas reveals cell identity and tissue-specific trajectories of aging
    1706. Exosomal long noncoding RNAs in aging and age‐related diseases
    1707. Cellular senescence in the lung across the age spectrum
    1708. Modulation of Human Neutrophil Peptides on P. aeruginosa Killing, Epithelial Cell Inflammation and Mesenchymal Stromal Cell Secretome Profiles
    1709. Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis
    1710. Alpha-1 Antitrypsin Deficiency and Accelerated Aging: A New Model for an Old Disease?
    1711. ERR agonism reverses mitochondrial dysfunction and inflammation in aging
    1712. Senescent hepatocytes in decompensated liver show reduced UPRMT and its key player, CLPP, attenuates senescence in vitro
    1713. Thrombin Induces Angiotensin II-Mediated Senescence in Atrial Endothelial Cells: Impact on Pro-Remodeling Patterns
    1714. Preventive role of Resveratrol against inflammatory cytokines and related diseases
    1715. Towards a unified mechanistic theory of aging
    1716. Iguratimod: a valuable remedy from the Asia Pacific region for ameliorating autoimmune diseases and protecting bone physiology
    1717. Autophagy and Immune Tolerance
    1718. Investigating the role of microRNAs in the hypoxic response in prostate cancer
    1719. Clinical Inference of Serum and Bone Sclerostin Levels in Patients with End-Stage Kidney Disease
    1720. Healthy aging: A bibliometric analysis of the literature
    1721. Danger signals and inflammaging in osteoarthritis
    1722. Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence
    1723. Orexins as novel therapeutic targets in inflammatory and neurodegenerative diseases
    1724. Skin Health from the Inside Out
    1725. SFRR-E 2019 ANNUAL MEETING “REDOX HOMEOSTASIS: FROM SIGNALING TO DAMAGE”
    1726. Oleuropein, a Bioactive Compound from Olea europaea L., as a Potential Preventive and Therapeutic Agent in Non-Communicable Diseases
    1727. Interleukin-1 and related cytokines in the regulation of inflammation and immunity
    1728. Plenary Sessions
    1729. Premature aging syndromes: From patients to mechanism
    1730. Understanding the origin and diversity of macrophages to tailor their targeting in solid cancers
    1731. Oxytocin Alleviates Cellular Senescence through Oxytocin Receptor‐Mediated ERK/Nrf2 Signalling
    1732. Inflammation and cancer: triggers, mechanisms, and consequences
    1733. Probiotic bacteria as modulators of cellular senescence: emerging concepts and opportunities
    1734. Immunobiology of atherosclerosis: a complex net of interactions
    1735. Beneficial effect of physical exercise on telomere length and aging, and genetics of aging-associated noncommunicable diseases
    1736. Inflammaging and oxidative stress in human diseases: from molecular mechanisms to novel treatments
    1737. Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis
    1738. Methylglyoxal Acts as a Tumor-Promoting Factor in Anaplastic Thyroid Cancer
    1739. The potential role of necroptosis in inflammaging and aging
    1740. Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories
    1741. Enhancement of epithelial cell autophagy induced by sinensetin alleviates epithelial barrier dysfunction in colitis
    1742. Age-related inflammation triggers skeletal stem/progenitor cell dysfunction
    1743. Quantitative proteomic analyses in blood: A window to human health and disease
    1744. The bystander effect contributes to the accumulation of senescent cells in vivo.
    1745. Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells
    1746. Antioxidative nanomaterials and biomedical applications
    1747. Health Benefits of Anti-aging Drugs
    1748. Exercise and dietary interventions in a rat model of metabolic knee osteoarthritis
    1749. Tissue Engineering and Regenerative Medicine Therapies for Cell Senescence in Bone and Cartilage
    1750. Placental Ageing in Adverse Pregnancy Outcomes: Telomere Shortening, Cell Senescence, and Mitochondrial Dysfunction
    1751. Regulatory mechanisms and clinical manifestations of musculoskeletal aging
    1752. Sex Steroids, Cognate Receptors, and Aging
    1753. Epigenetic changes during aging and their reprogramming potential
    1754. NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis
    1755. Premature cell senescence in human skin: dual face in chronic acquired pigmentary disorders
    1756. 140-3D Hydrogels and Bioinks for Realistic In Vitro Modelling and Bioprinting
    1757. Impact of aging on bone, marrow and their interactions
    1758. FRI0531 THE ARTICULAR PROTECTION EFFECT OF ISORHAMNETIN IN THE RATS OF MONOSODIUM IODOACETATE-INDUCED OSTEOARTHRITIS
    1759. Benefits of tree nuts consumption on aging and age-related diseases: mechanisms of actions
    1760. Regulation of Wound Healing by the NRF2 Transcription Factor—More Than Cytoprotection
    1761. Enhancement of therapeutic efficacy by immunomodulation in human mesenchymal stem cells
    1762. PAK4 signaling in development and cancer
    1763. Transposable Elements, Inflammation and Neurological Disease
    1764. Drugs that target aging: how do we discover them?
    1765. Extracellular matrix roles in cardiorenal fibrosis: Potential therapeutic targets for CVD and CKD in the elderly
    1766. Murine models of accelerated aging and musculoskeletal disease
    1767. Identification of differentially expressed transcription factors and dissecting the role of DREAM complex associated components in cellular senescence
    1768. Inflammation and Liver Cancer: Molecular Mechanisms and Therapeutic Targets
    1769. Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model
    1770. Acquired Immune Response to Infection
    1771. MHY2233 Attenuates Replicative Cellular Senescence in Human Endothelial Progenitor Cells via SIRT1 Signaling
    1772. Methods to Quantify the NF-κB Pathway During Senescence
    1773. Somatic mutations in healthy cells and age-associated diseases
    1774. HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity
    1775. Investigating the immune system in chrONIC kidney disease-the SONIC study
    1776. JOINT MEETING AGI–SIMAG
    1777. Rejuvenation: Turning back the clock of aging kidney
    1778. Characterisation of an in vitro aged cell culture model
    1779. L1CAM and its role in cellular senescence
    1780. The role of the cell-matrix interface in aging and its interaction with the renin-angiotensin system in the aged vasculature
    1781. Time for the systems-level integration of aging: Resilience enhancing strategies to prevent Alzheimer’s disease
    1782. Epigenetics and Pharmacoepigenetics of Age-Related Neurodegenerative Disorders
    1783. Molecular basis of senescence transmitting in the population of human endometrial stromal cells
    1784. Shared and distinct mechanisms of fibrosis
    1785. Skeletal Muscle Stem Cells
    1786. Are There Reliable Biomarkers for Immunosenescence and Inflammaging?
    1787. Epidermal growth factor (EGF) intralesional infiltrations: from the bench to the diabetic ulcers cells
    1788. Senescence surveillance: the interplay between the immune system and senescent cells
    1789. Exosomes as Emerging Pro-Tumorigenic Mediators of the Senescence-Associated Secretory Phenotype
    1790. Age-Associated Changes in the Immune System and Blood–Brain Barrier Functions
    1791. Recent advances in understanding the phenotypes of osteoarthritis
    1792. Inducing Age Related Changes in Microglia as a Model for Neurodegenerative Disease
    1793. Convallatoxin protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB signaling through activation of PPARγ
    1794. Innate immune cell crosstalk induces melanoma cell senescence
    1795. Characterization and Analysis of Neural Progenitor Cells from Primary Progressive Multiple Sclerosis Patients
    1796. Targeting Cell Senescence for the Treatment of Age-Related Bone Loss
    1797. Ell3 functions as a critical decision maker at the crossroad between stem cell senescence and apoptosis
    1798. The role of exosomes in regenerative medicine
    1799. Mitochondrial dysfunction and cell senescence: deciphering a complex relationship
    1800. The Effects of IL-1β on Astrocytes are Conveyed by Extracellular Vesicles and Influenced by Age
    1801. The role of senescence in cancer development
    1802. 41th Volume Index
    1803. The proteome of ulcerative colitis-Functional analyses of the active disease and the remission state in comparison with healthy controls
    1804. Allostatic load and ageing: linking the microbiome and nutrition with age-related health
    1805. Rosiglitazone ameliorates senescence and promotes apoptosis in ovarian cancer induced by olaparib
    1806. Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with …
    1807. Methods for CPP Functionalization
    1808. Probing the impact of the maternal environment on foetal development: Can high-resolution telomere analysis predict prenatal adversity?
    1809. Bone marrow stromal cells from β-thalassemia patients have impaired hematopoietic supportive capacity
    1810. Recurrent circadian fasting (RCF) improves blood pressure, biomarkers of cardiometabolic risk and regulates inflammation in men
    1811. Noncoding RNAs: Bridging Regulation of Circadian Rhythms and Inflammation
    1812. Accelerated cardiomyocyte senescence contributes to late-onset doxorubicin-induced cardiotoxicity.
    1813. SEXUAL ABUSE: HOW CAN WE KNOW?
    1814. Metabolic phenotyping of the human microbiome
    1815. Reduced RNA turnover as a driver of cellular senescence
    1816. The role of metabolism in the anti-tumor cytotoxicity of natural killer cells
    1817. Microncronucleus index in epithelial exfoliated cells of urothelium and buccal mucosa, and peripheral blood lymphocytes of patients with papillary urothelial …
    1818. Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells
    1819. Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and cartilage regeneration in osteoarthritis
    1820. PTEN loss regulates alveolar epithelial cell senescence in pulmonary fibrosis depending on Akt activation
    1821. Mitophagy, Mitochondrial Dynamics, and Homeostasis in Cardiovascular Aging
    1822. TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis—Updated 2019
    1823. Know your enemy: Genetics, aging, exposomic and inflammation in the war against triple negative breast cancer
    1824. NAD+ in brain aging and neurodegenerative disorders
    1825. Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies
    1826. miR-140 Attenuates the Progression of Early-Stage Osteoarthritis by Retarding Chondrocyte Senescence
    1827. The dark side of fibroblasts: cancer-associated fibroblasts as mediators of immunosuppression in the tumor microenvironment
    1828. The role of signaling pathways of inflammation and oxidative stress in development of senescence and aging phenotypes in cardiovascular disease
    1829. Emerging targets of disease-modifying therapy for systemic sclerosis
    1830. Identification and characterization of inter-species aging-related transcriptomic regulators
    1831. Mouse Models of Accelerated Cellular Senescence
    1832. Cranberries–potential benefits in patients with chronic kidney disease
    1833. Mitochondrial Homeostasis and Cellular Senescence
    1834. Amelioration of age‐related brain function decline by Bruton’s tyrosine kinase inhibition
    1835. NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice
    1836. Paeonol prevents IL-1β-induced inflammatory response and degradation of type II collagen in human primary chondrocytes
    1837. Scarless wound healing: From development to senescence
    1838. β cell responses to inflammation
    1839. The modular proteome and its significance
    1840. Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies
    1841. Ferroptosis, a new form of cell death: opportunities and challenges in cancer
    1842. Senescence-associated metabolomic phenotype in primary and iPSC-derived mesenchymal stromal cells
    1843. Leukocyte Telomere Length in Patients with Radiographic Knee Osteoarthritis
    1844. Concepts in Inflammatory Bowel Disease Management
    1845. Protein Signatures of Centenarians and Their Offspring Suggest Centenarians Age Slower than Other Humans
    1846. Tumor microenvironment: Interactions and therapy
    1847. The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1
    1848. Stromal cell-derived factor-1 (CXCL12) and its role in bone and muscle biology
    1849. Measuring biological aging in humans: A quest
    1850. Amelioration of Ductular Reaction by Stem Cell Derived Extracellular Vesicles in MDR2 Knockout Mice via Lethal‐7 microRNA
    1851. Activation of melatonin receptor 2 but not melatonin receptor 1 mediates melatonin‐conferred cardioprotection against myocardial ischemia/reperfusion injury
    1852. Proteomic Markers for Depression
    1853. Induction of Fibroblast Senescence During Mouse Corneal Wound Healing
    1854. Regulation of Thirst and Vasopressin Release
    1855. Hyper-osmolarity environment-induced oxidative stress injury promotes nucleus pulposus cell senescence in vitro
    1856. Novel drug targets in idiopathic pulmonary fibrosis
    1857. Sleep, stress, and immunity
    1858. Meeting report: Metastasis Research Society (MRS) 17th Biennial conference and associated Young Investigator Satellite Meeting (YISM) on cancer metastasis
    1859. Targeting pro-senescence mitogen activated protein kinase (Mapk) enzymes with bioactive natural compounds
    1860. Coordination of immune-stroma crosstalk by IL-6 family cytokines
    1861. Long non-coding RNA CDKN2B-AS1 reduces inflammatory response and promotes cholesterol efflux in atherosclerosis by inhibiting ADAM10 expression
    1862. Proceedings of the 2018 Santa Fe Bone Symposium: Advances in the Management of Osteoporosis
    1863. The telomere world and aging: Analytical challenges and future perspectives
    1864. The cross-talk between sphingolipids and insulin-like growth factor signaling: significance for aging and neurodegeneration
    1865. Young Hematopoietic Stem Cells Ameliorate Age-Associated Phenotypes and Extend Lifespan in Mice
    1866. MicroRNA networks modulate oxidative stress in cancer
    1867. The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage
    1868. Crosstalk between HGF and TGF-ß signaling pathways in adult liver progenitor cells and hepatocellular carcinoma cells
    1869. The Evolving Role of CD8+ CD28− Immunosenescent T Cells in Cancer Immunology
    1870. Astrocytes autophagy in aging and neurodegenerative disorders
    1871. Stem cells: a path towards improved epilepsy therapies
    1872. Novel function of PiT1/SLC20A1 in LPS-related inflammation and wound healing
    1873. Biomarkers of Aging (With a Clinical Potential in Oncology)
    1874. Mitochondrial oxidative stress-induced transcript variants of ATF3 mediate lipotoxic brain microvascular injury
    1875. MOTOR BEHAVIOR
    1876. Mediterranean Diet (Prong-4)
    1877. Resveratrol: A New Potential Therapeutic Agent for Melanoma?
    1878. EFFECT OF ADVANCED MATERNAL AGE ON PREGNANCY
    Share
    0
    INTERSTELLAR BLEND
    INTERSTELLAR BLEND

    Related posts

    October 6, 2020

    PPARY2


    Read more
    September 16, 2020

    NMDA & ANXIETY & DEPRESSION


    Read more
    September 16, 2020

    INFECTOBESITY


    Read more

    Comments are closed.

    Recent Posts

    • PPARY2
    • NMDA & ANXIETY & DEPRESSION
    • INFECTOBESITY
    • Anti-Acne effect of Flavonoids and Polyphenols
    • NOOTROPICS
    © 2021 Interstellar Blends | Activate Your Super Powers!. © 2019 Interstellar Blends | Activate Your Super Powers!. All Rights Reserved.

    Mandatory FDA Disclaimer
    Privacy Policy
    Terms and Conditions
    Have Questions?
    Contact Gavin Robert McGowen Here

    Join the following facebook groups to learn more:
    Ultimate Weightloss Challenge , Dry Fasting, Longevity Agents , Interstellar Blend Seven Sages, The Infinitely Postive, THE INTERSTELLAR BLEND CHALLENGE: Fluid Restricted Fasting w/ Superherbs

    Love this Website? Contact David Rodriguez to build you one!