logotest1logotest1logotest1logotest1
  • SHOP
  • COMBOS
  • TESTIMONIALS
  • CART
  • INGREDIENTS
    • 2-DEOXY-D-GLUCOSE (2DG)
    • ACACIA CYANOPHYLLA FLOWER
    • ACORI GRAMINEI RHIZOMA
    • AEGLE MARMELOS CORREA
    • AGARICUS BLAZEI
    • AGED GARLIC EXTRACT
    • AFRAMOMUM MELEGUETA
    • ALOE ARBORESCENS
    • ALBIZIA
    • ALPINIA OFFICINARUM
    • ALTERNANTHERA SESSILIS
    • AMERICAN GINSENG
    • AMYGDALIN
    • ANACYCLUS PYRETHRUM
    • ANGELICA ARCHANGELICA
    • ANGELICA SINENSIS
    • ANTRODIA
    • APIGENIN
    • ARTICHOKE LEAF
    • ARTOCARPIN
    • AJUGA TURKESTANICA
    • ASHWAGANDHA
    • ASPALATHIN
    • ASTRAGALUS COMPLANATUS
    • AVENA SATIVA
    • BACOPA MONNIERI
    • BAVACHIN
    • BEE POLLEN
    • BETULINIC ACID
    • BOSWELLIC ACID
    • BREVILIN A
    • CAMPESTEROL
    • CAPSAICIN
    • CARCININE
    • CASTICIN
    • CHRYSIN
    • CIANIDANOL
    • CINNAMOMUM ZEYLANICUM
    • CITRULLUS COLOCYNTHIS
    • CITRUS RETICULATA PEEL
    • CODONOPSIS
    • CONJUGATED LINOLEIC ACID
    • COSTUNOLIDE
    • CYANIDIN
    • CUCURBITACIN D
    • DAIDZEIN
    • DECURSIN
    • DELPHINIDIN
    • DIGITALIS PURPREA (DIGOXIN)
    • DIOSMIN
    • ECKLONIA CAVA
    • ELLAGIC ACID
    • EMBELIN
    • ERIODICTYOL
    • GALLIC ACID
    • GLYCITEIN
    • GLYCYRRHIZIN
    • HYPERFORIN
    • ICARIIN
    • ISORHAMNETIN
    • ISOORIENTIN
    • ISOVITEXIN
    • JACEOSIDIN
    • KAEMPFEROL
    • KIGELIA AFRICANA
    • KURARINONE
    • LEMON BALM
    • LICORICIDIN
    • LIPOIC ACID
    • LUPEOL
    • MAGNOLOL
    • MENAQUINONE 4
    • MULBERRY LEAF
    • NARINGENIN
    • NOBILETIN
    • OLEACEIN
    • OLEANOLIC ACID
    • OLIVE OIL
    • ORIDONIN
    • PARTHENOLIDE
    • PHLOROGLUCINOL
    • PHLORIZIN
    • PICEATANNOL
    • PRISTIMERIN
    • PROANTHOCYANIDINS
    • PROCYANIDIN B3
    • PSEUDOLARIC ACID B
    • PTEROSTILBENE
    • RUTIN
    • SOLIDAGO VIRGAUREA
    • TANGERETIN
    • TARAXASTEROL
    • TRICHOSTATIN A
    • WEDELOLACTONE
    • WOGONIN
    • YERBA MATE
  • ABOUT
  • SCIENTIFIC STUDIES
    • ADAPTOGENS
    • ADIPOCYTE APOPTOSIS (KILLING FAT CELLS)
    • ADDICTION & THE BRAIN
    • ADDICTION & STRESS
    • ADDICTION WITHDRAWAL
    • ADIPOCYTE DEDIFFERENTIATION (THE REVERSAL OF FAT FORMATION)
    • ADIPOCYTE DIFFERENTIATION
    • ADROPIN
    • ALLERGIES & CYTOKINES
    • ALDOSTERONE & OBESITY/HYPERTENSION
    • ALZHEIMER’S, DEMENTIA, PARKINSON’S
    • ANTI-ACNE EFFECT OF FLAVONOIDS AND POLYPHENOLS
    • ADVANCED GLYCATION END PRODUCTS (AGES)
    • ADDICTION TREATMENT
    • ADDICTION & DOPAMINE
    • AMPK
    • ANTI AGING
    • ANTIAGING EFFECTS OF COFFEE
    • ANTI-AGING EFFECTS OF FLAVONOIDS & POLYPHENOLS
    • ANTI-APOPTOTIC PATHWAYS
    • ANTI ATHEROGENIC
    • ANTI-CANCER EFFECTS OF FLAVONOIDS & POLYPHENOLS
    • ANTI CARIOGENIC (Protecting From Tooth Decay)
    • ANTI COVID-19 EFFECTS OF MEDICINAL PLANTS, FLAVONOIDS & POLYPHENOLS
    • ANTI GLYCATIVE
    • ANTI GLYCATION AGENTS
    • ANTI-INFLAMMATORY EFFECTS OF FLAVONOIDS & POLYPHENOLS
    • ANTI-VIRAL EFFECTS OF FLAVONOIDS & POLYPHENOLS
    • ANTI WRINKLE AGENTS
    • ANXIOGENIC
    • ANXIOLYTIC
    • APOPTOSIS
    • APOPTOSIS IN 3T3-L1
    • AUTOPHAGY
    • BCL-2
    • BCL-W
    • BCL-XL
    • BDNF
    • BECLIN-1 & AUTOPHAGY
    • BH3 MIMETICS
    • BIM aka BCL2L11
    • BIOMIMETIC HYDROXYAPATITE
    • BMI-1
    • BPA & OBESITY
    • BRASSINOSTEROIDS
    • CALORIE RESTRICTION
    • CALORIE RESTRICTION & LIFESPAN EXTENSION
    • CARBAMYLATION
    • CARBONYL SCAVENGER
    • CARBONYL STRESS
    • CARDIOPROTECTIVE AGENTS
    • CARDIAC GLYCOSIDES
    • CATALASE
    • CELL CYCLE ARREST
    • CENTENARIANS
    • CDK5
    • CHOLESTEROL EFFLUX
    • COGNITIVE ENHANCEMENT
    • COLD SHOCK PROTEINS
    • COLD-INDUCIBLE RNA-BINDING PROTEIN (CIRBP) & DNA REPAIR
    • CONDITIONED PLACE PREFERENCE
    • CORTICOTROPIN RELEASING FACTOR
    • CRYOTHERAPY
    • CRYOLIPOLYSIS: FREEZING FAT TO DEATH
    • CYP2E1
    • CYTOKINES IN PAIN, INFLAMMATION & AGING
    • DAF-16
    • DEPERSONALIZATION
    • DIABETES & CANCER
    • DIHYDROTESTOSTERONE (DHT)
    • DNA METHYLATION & AGING
    • DNA REPAIR
    • DNA REPAIR VIA FLAVONOIDS & POLYPHENOLS
    • DRY FASTING AND FLUID RESTRICTION FASTING
    • DYNORPHIN
    • ELLAGITANNINS
    • ENDOCRINE DISRUPTING CHEMICALS
    • ENLARGED HEART AND CARDIOMEGALY
    • EPIGENETIC ALTERATIONS
    • EPIGENETIC MODIFIERS
    • EPINEPHRINE
    • ERGOGENIC AGENTS (INCREASE ATHLETIC PERFORMANCE)
    • EXCITOXICITY & THE BRAIN
    • EXTRACELLULAR MATRIX STIFFENING (10TH HALLMARK OF AGING)
    • EXTRACELLULAR MICROVESICLES
    • EXTENDS LIFESPAN
    • EXTINCTION TRAINING
    • FASTING & THE BRAIN
    • FASTING & CANCER
    • FASTING MIMICKING DIET
    • FEAR EXTINCTION
    • FGF21
    • FLAVONES
    • GABA (γ-AMINOBUTYRIC ACID)
    • GALLOTANNINS
    • GLUCONEOGENESIS
    • GLUCOCORTICOID RECEPTOR ACTIVATION
    • GLUTAMATE & BRAIN
    • GLYCATION
    • GUT BRAIN AXIS
    • GYPENOSIDE
    • KLOTHO
    • K OPIOD RECEPTOR & ADDICTION
    • FASTING, CALORIE RESTRICTION & EXTENDING LIFESPAN
    • FGF21
    • FOXO3
    • FOXO4
    • HALLMARKS OF AGING
    • HAIR GROWTH
    • HAIR REGENERATION
    • HAIR REPIGMENTATION
    • HEPATOPROTECTIVE AGENTS (KEEPING LIVER HEALTHY)
    • HMGB1
    • HORMESIS
    • HPA AXIS
    • HSP70, THE ANTI-AGING PROTEIN
    • HSP90 INHIBITORS
    • HYPERGLYCEMIA
    • HYPERALGESIA
    • HYPERINSULINEMIA
    • HYPOTHALAMIC PITUITARY ADRENAL HPA AXIS
    • HYPOACTIVE SEXUAL DESIRE (WHY PEOPLE HAVE ZERO SEX DRIVE)
    • HYPOCRETIN OREXIN
    • IKK
    • IL-6/STAT3
    • IRISIN
    • ISOFLAVONES
    • IMMUNOSENESCENCE
    • INHIBITION OF ADVANCED GLYCATION END PRODUCTS
    • INCREASE PROTEIN SYNTHESIS
    • INCREASES SPERMATOGENESIS
    • INFECTOBESITY
    • INFLAMMATION & ANXIETY
    • INFLAMMATION & CANCER
    • INFLAMMATION & DEPRESSION
    • INFLAMMATION & OBESITY
    • INFLAMMAGING
    • INHIBITION OF RENAL GLUCOSE REABSORPTION
    • INSULIN & AGING
    • INSULIN & CANCER: HOW INSULIN LITERALLY PROTECTS CANCER CELLS FROM BEING KILLED
    • INSULIN & MTOR
    • INSULIN & OBESITY
    • INSULIN OXIDATIVE STRESS
    • INTERMITTENT FASTING
    • JAK INHIBITION ALLEVIATES SASP
    • JNK ACTIVATION PREVENTS PREMATURE SENESCENCE
    • KETONE BODIES
    • KETOGENIC DIET
    • LACTOBACILLUS REUTERI
    • LACTOFERRIN
    • LEYDIG CELL STEROIDOGENESIS
    • LIFESPAN EXTENSION
    • LIVER REGENERATION
    • LIPOLYTIC AGENTS
    • LIPID DROPLETS
    • LIPOLYSIS (THE DECOMPOSITION OF BODY FAT)
    • LOWERING CHOLESTEROL THRU FASTING, DIET & MEDICINAL PLANTS
    • MATRIX METALLOPROTEINASES (MMPs)
    • MCL-1
    • MDM2 INHIBITION AS SASP INHIBITOR
    • MEDICINAL MUSHROOMS
    • MEDITERRANEAN DIET
    • METABOLIC REPROGRAMMING
    • METABOLIC SYNDROME
    • METHIONINE RESTRICTION
    • MITOCHONDRIAL UNCOUPLING
    • MONKEYPOX
    • MSG (MONOSOSODIUM GLUTAMATE)
    • MUSCLE FORCE PRODUCTION
    • MUSCLE ATROPHY (PREVENTING)
    • MYOGENESIS
    • MYOSTATIN INHIBITION
    • MYOSTATIN INHIBITION PRESERVES MUSCLE
    • mTORC2
    • mTOR: THE RAPID AGING PATHWAY
    • NATURAL ANTICOAGULANTS
    • NATURAL AROMATASE INHIBITORS
    • NEUROGENESIS (GROWING NEW BRAIN CELLS)
    • NEUROCHEMISTRY OF ADDICTION
    • NEUROPLASTICITY
    • NEUROINFLAMMATION
    • NEUROPROTECTIVE AGENTS
    • NEUTRALIZING OXIDATIVE STRESS WITH MEDICINAL PLANTS
    • NMDA & ANXIETY & DEPRESSION
    • NMDA RECEPTOR & FEAR
    • NON OPIOD ANALGESICS
    • NOOTROPICS
    • NORADRENERGIC
    • NOREPINEPHRINE
    • NRF2: MASTER REGULATOR OF THE AGING PROCESS
    • NF-KB
    • OBESOGENS
    • ONCOGENE ACTIVATION INDUCED SENESCENCE
    • ORGANOTINS
    • OVERNUTRITION
    • OXIDATIVE STRESS & AGING
    • P16INK4A
    • P38MAPK
    • P53: TUMOR SUPRESSOR
    • PERIODONTITIS
    • PHOSPHATIDYLINOSITOL 3 KINASE
    • PHYTOCHEMICALS
    • PHYTOSTEROLS
    • PHYTOSTANOLS
    • PHYTOECDYSTEROIDS
    • PROANTHOCYANIDINS
    • PROTEIN CARBONYLATION
    • POLYAMINES & THEIR EFFECT ON BRAIN (NMDA, DEPRESSION, SUICIDE RISK)
    • POLYPHENOLS AS COVID-19 TREATMENT & PREVENTION
    • PPARY2
    • PREMATURE SENESCENCE
    • PREVENTING SKIN AGING
    • PUFAS
    • PURGATIVES
    • RAPAMYCIN (MTOR INHIBITION)
    • RED WINE
    • RENAL (KIDNEY) PROTECTIVE AGENTS
    • REMINERALIZATION OF TEETH
    • REPAIR OF DNA BREAKS “DOUBLE STRAND”
    • RESTORE INSULIN SENSITIVITY
    • REVERSAL OF OBESITY
    • SASP & ADIPOSE TISSUE
    • SEX HORMONE BINDING GLOBULIN
    • SENESCENT CELLS, SASP & SENOLYTICS
    • SENESCENCE-BETA-GALACTOSIDASE (SA-β-gal or SABG)
    • SGLT2 INHIBITORS
    • SGLT2 INHIBITION FOR LIFESPAN EXTENSION
    • SHBG
    • SIRT1
    • SKELETAL MUSCLE HYPERTROPHY (THE SCIENCE OF BUILDING MUSCLE)
    • SKIN ELASTICITY
    • SKIN PHOTOAGING (Preventing & Repairing)
    • SLEEP DEPRIVATION AS THERAPY FOR DEPRESSION
    • SIRT1 & LONGEVITY
    • SMALLPOX
    • SUGAR & AGING
    • STAR PROTEIN
    • STAT3
    • STEM CELL EXHAUSTION
    • STEM CELL REGENERATION
    • STEM CELL THERAPY
    • STIMULATED LIPOLYSYS
    • STEROIDOGENESIS (THE PRODUCTION OF HORMONES IN BODY)
    • STREPTOCOCCUS MUTANS (MAIN BACTERIA BEHIND TOOTH DECAY)
    • STRESS & AGING
    • STRESS & THE BRAIN
    • TELOMERE SHORTENING & PREMATURE AGING
    • TIME RESTRICTED FEEDING
    • THROMBOLYTICS (PLANT BASED)
    • TRAUMATIC BRAIN INJURY (HEALING)
    • TRYPTOPHAN HYDROXYLASE 2
    • VISCERAL ADIPOSITY
    • XENOBIOTICS
    • XENOESTROGEN
  • HOME
  • CONTACT
  • INTERSTELLAR 88/8: EXTREME WEIGHTLOSS PROTOCOL
  • The Ultimate Dry Fasting Resource
0

$0.00

✕
blank
DEPERSONALIZATION
August 3, 2022
blank
POLYPHENOLS AS COVID-19 TREATMENT & PREVENTION
August 3, 2022
Post Views: 0
  1. Oxidative stress, toxicology, and pharmacology of CYP2E1
  2. Genetic polymorphism in CYP2E1: Population distribution of CYP2E1 activity
  3. CYP2E1 and oxidative liver injury by alcohol
  4. Human CYP2E1 is regulated by miR-378
  5. Role of CYP2E1 in the Hepatotoxicity of Acetaminophen (∗)
  6. CYP2E1
  7. CYP2E1: from ash to nash
  8. Human hepatic CYP2E1 expression during development
  9. Ethanol Induces CYP2E1 by Protein Stabilization: ROLE OF UBIQUITIN CONJUGATION IN THE RAPID DEGRADATION OF CYP2E1 (∗)
  10. Role of CYP2E1 in Diethylnitrosamine-Induced Hepatocarcinogenesis In vivo
  11. CYP2E1-dependent toxicity and oxidative stress in HepG2 cells
  12. Different regulation and expression of the human CYP2E1 gene due to the Rsal polymorphism in the 5′-flanking region
  13. Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression
  14. The CYP2E1-humanized transgenic mouse: role of CYP2E1 in acetaminophen hepatotoxicity
  15. Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1
  16. Genetic polymorphism of human CYP2E1: characterization of two variant alleles
  17. Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation
  18. Reduction of benzene metabolism and toxicity in mice that lack CYP2E1 expression
  19. CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan
  20. CYP2E1 and risk of chemically mediated cancers
  21. Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1
  22. Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression
  23. CYP2E1 mediated isoniazid-induced hepatotoxicity in rats
  24. Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1.
  25. CYP2E1 is not involved in early alcohol-induced liver injury
  26. Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese.
  27. Detection and characterization of novel polymorphisms in the CYP2E1 gene.
  28. Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation
  29. CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury
  30. Chlorzoxazone, a selective probe for phenotyping CYP2E1 in humans.
  31. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
  32. Genetic and dietary predictors of CYP2E1 activity: a phenotyping study in Hawaii Japanese using chlorzoxazone
  33. CYP2E1—biochemical and toxicological aspects and role in alcohol-induced liver injury
  34. CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease
  35. Developmental Expression of CYP2E1 in the Human Liver: Hypermethylation Control of Gene Expression During the Neonatal Period
  36. Role of CYP2E1 in thioacetamide-induced mouse hepatotoxicity
  37. The alcohol-inducible form of cytochrome P450 (CYP2E1): role in toxicology and regulation of expression
  38. Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice
  39. The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model
  40. Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1
  41. Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling
  42. Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: evidence that CYP2E1 possesses a rapid phase half …
  43. Development and properties of HepG2 cells that constitutively express CYP2E1
  44. Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol
  45. CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis
  46. Human CYP2E1 mediates the formation of glycidamide from acrylamide
  47. Role of CYP2E1 in the epoxidation of acrylamide to glycidamide and formation of DNA and hemoglobin adducts
  48. CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane
  49. Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics
  50. Iron and CYP2E1-dependent oxidative stress and toxicity
  51. Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis
  52. Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity
  53. Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1.
  54. Diallylsulfide and allylmethylsulfide are uniquely effective among organosulfur compounds in inhibiting CYP2E1 protein in animal models
  55. CYP2E1‐mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells
  56. In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians.
  57. CYP2E1-dependent toxicity and up-regulation of antioxidant genes
  58. Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1
  59. Polymorphisms in GSTT1, GSTZ1, and CYP2E1, Disinfection By-products, and Risk of Bladder Cancer in Spain
  60. Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1
  61. Mechanisms of down-regulation of CYP2E1 expression by inflammatory cytokines in rat hepatoma cells
  62. Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect
  63. Advances in the interpretation and prediction of CYP2E1 metabolism from a biochemical perspective
  64. Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia
  65. Cytochrome P450IIE1 (CYP2E1) is induced by skatole and this induction is blocked by androstenone in isolated pig hepatocytes
  66. Association of CYP2E1 gene polymorphism with predisposition to cancer development
  67. CYP2E1 substrate inhibition: Mechanistic interpretation through an effector site for monocyclic compounds
  68. Transcriptional control of the rat hepatic CYP2E1 gene
  69. Transcriptional control of CYP2E1 in the perivenous liver region and during starvation
  70. Mechanism-based inactivation of human CYP2E1 by diethyldithocarbamate
  71. Nrf2 and antioxidant defense against CYP2E1 toxicity
  72. Acetaldehyde as well as ethanol is metabolized by human CYP2E1
  73. NAT2 and CYP2E1 polymorphisms and susceptibility to first-line anti-tuberculosis drug-induced hepatitis
  74. Associations of CYP1A1, GSTM1, and CYP2E1 Polymorphisms with Lung Cancer Suggest Cell Type Specificities to Tobacco Carcinogens
  75. Pharmacokinetic consequences of induction of CYP2E1 by ligand stabilization
  76. Activity of CYP2E1 and CYP3A enzymes in adults with moderate alcohol consumption: a comparison with nonalcoholics
  77. Loss of CYP2E1 and CYP1A2 activity as a function of acetaminophen dose: relation to toxicity
  78. Acetone catabolism by cytochrome P450 2E1: studies with CYP2E1-null mice
  79. Genetic polymorphisms of CYP2E1, GSTM1, and GSTT1; environmental factors and risk of oral cancer.
  80. Regulation of CYP2E1 by ethanol and palmitic acid and CYP4A11 by clofibrate in primary cultures of human hepatocytes
  81. Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1
  82. Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1
  83. CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophaghy in HepG2 E47 cells
  84. Effects of rifampin on CYP2E1-dependent hepatotoxicity of isoniazid in rats
  85. CYP2E1 activity in patients with alcoholic liver disease
  86. Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen
  87. CYP2E1-dependent oxidative stress and toxicity: role in ethanol-induced liver injury
  88. Lipid peroxidation, CYP2E1 and arachidonic acid metabolism in alcoholic liver disease in rats
  89. CYP2E1-mediated modulation of valproic acid-induced hepatocytotoxicity
  90. Genetic Polymorphisms of CYP2E1 and Risk of Colorectal Cancer: The Fukuoka Colorectal Cancer Study
  91. Genetic polymorphism of GSTM1, CYP2E1 and CYP2D6 in Egyptian bladder cancer patients
  92. Cytochrome P450 2E1 (CYP2E1) is essential for acrylonitrile metabolism to cyanide: comparative studies using CYP2E1-null and wild-type mice
  93. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components
  94. Expression of CYP2E1 during human fetal development: methylation of the CYP2E1 gene in human fetal and adult liver samples
  95. CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of γ-glutamylcysteine synthetase
  96. Genetic polymorphisms of NAT2, CYP2E1 and GST enzymes and the occurrence of antituberculosis drug-induced hepatitis in Brazilian TB patients
  97. Genotype and allele frequencies of polymorphic CYP2E1 in the Turkish population
  98. The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage
  99. Ethanol induction of CYP2A5: permissive role for CYP2E1
  100. Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse
  101. CYP2E1 and catalase influence ethanol sensitivity in the central nervous system
  102. Acetaldehyde as a substrate for ethanol-inducible cytochrome P450 (CYP2E1)
  103. Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice
  104. CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people
  105. Red Meat Intake, CYP2E1 Genetic Polymorphisms, and Colorectal Cancer Risk
  106. Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1
  107. Comparison of germ cell mutagenicity in male CYP2E1-null and wild-type mice treated with acrylamide: evidence supporting a glycidamide-mediated effect
  108. Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver
  109. Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and CYP2E1 (–/–) mice
  110. Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes
  111. Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione
  112. Induction of catalase, alpha, and microsomal glutathione S‐transferase in CYP2E1 overexpressing HepG2 cells and protection against short‐term oxidative stress
  113. Tissue-specific expression and methylation of the human CYP2E1 gene
  114. Evaluation of caffeine as a test drug for CYP1A2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations.
  115. Induction and recovery time course of rat brain CYP2E1 after nicotine treatment
  116. Histone modification-mediated CYP2E1 gene expression and apoptosis of HepG2 cells
  117. Genetic variations of NAT2 and CYP2E1 and isoniazid hepatotoxicity in a diverse population
  118. Association between CYP2E1 genetic polymorphisms and lung cancer risk: a meta-analysis
  119. Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous system
  120. Genetic polymorphisms in GSTM1,-P1,-T1, and CYP2E1 and the risk of adult brain tumors
  121. The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphisms in a Finish study population
  122. Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation
  123. Synergistic toxicity of iron and arachidonic acid in HepG2 cells overexpressing CYP2E1
  124. Post-transcriptional regulation of rat CYP2E1 expression: role of CYP2E1 mRNA untranslated regions in control of translational efficiency and message stability
  125. CYP2E1* 1D regulatory polymorphism: association with alcohol and nicotine dependence
  126. Ethanol‐mediated carcinogenesis in the human esophagus implicates CYP2E1 induction and the generation of carcinogenic DNA‐lesions
  127. Role of alcohol and genetic polymorphisms of CYP2E1 and ALDH2 in breast cancer development
  128. Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and CYP2E1 …
  129. Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation
  130. Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian …
  131. Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias
  132. Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single ingestion of watercress
  133. Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole
  134. Elucidation of CYP2E1 5′ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer
  135. The role of CYP2E1 and 2B1 in metabolic activation of benzene derivatives
  136. The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis
  137. Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling
  138. Construction and assessment of models of CYP2E1: predictions of metabolism from docking, molecular dynamics, and density functional theoretical calculations
  139. Acetoacetate induces CYP2E1 protein and suppresses CYP2E1 mRNA in primary cultured rat hepatocytes
  140. The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: effect on age of presentation and dependence on alcohol …
  141. Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis
  142. Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression
  143. Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1
  144. Constitutive and inducible expression of hepatic CYP2E1 in leptin-deficient ob/ob mice
  145. CYP2E1 and NQO1 genotypes, smoking and bladder cancer
  146. Study of polymorphisms in the CYP2E1 gene in patients with alcoholic pancreatitis
  147. The GST T1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function
  148. Role of the Liver-Enriched Transcription Factor HNF-1α in Expression of the CYP2E1 Gene
  149. Ontogeny of hepatic CYP1A2 and CYP2E1 expression in rat
  150. Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo
  151. Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice
  152. Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol‐induced oxidative DNA damage in rodent liver
  153. The effect of ethanol-induced CYP2E1 on proteasome activity: the role of 4-hydroxynonenal
  154. Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine
  155. Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning.
  156. Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome?
  157. Genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 associated with head and neck cancer
  158. Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats
  159. Risk assessment: toxicity from chemical exposure resulting from enhanced expression of CYP2E1
  160. … for the Expression of Recombinant Human Cytochrome P450s inEscherichia coliUsing Bacterial Signal Peptides: Expression of CYP3A4, CYP2A6, and CYP2E1
  161. Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver
  162. Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in Chinese Han populations from four different geographic areas of Mainland China
  163. Transgenic alfalfa plants co-expressing glutathione S-transferase (GST) and human CYP2E1 show enhanced resistance to mixed contaminates of heavy metals and …
  164. Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1
  165. Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers …
  166. Construction of a CYP2E1-template system for prediction of the metabolism on both site and preference order
  167. Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes
  168. Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1
  169. CYP2E1 is preferentially expressed in Clara cells of murine lung: localization by in situ hybridization and immunohistochemical methods.
  170. NQO1, MPO, CYP2E1, GSTT1 and GSTM1 polymorphisms and biological effects of benzene exposure—a literature review
  171. Spectrophotometric Analysis of Human CYP2E1-Catalyzed p-Nitrophenol Hydroxylation
  172. An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A)
  173. Heteromeric complex formation between CYP2E1 and CYP1A2: evidence for the involvement of electrostatic interactions
  174. CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation
  175. Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1, 3-dimethyluric acid formation
  176. Inhibition of CYP2E1 Reverses CD4+ T-Cell Alterations in Trichloroethylene-Treated MRL+/+ Mice
  177. Genetic polymorphisms of CYP2D6, CYP1A1 and CYP2E1 in the South-Amerindian population of Chile.
  178. Amelioration of oxidative stress by dandelion extract through CYP2E1 suppression against acute liver injury induced by carbon tetrachloride in sprague‐dawley rats
  179. CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes
  180. St. John’s wort extract induces CYP3A and CYP2E1 in the Swiss Webster mouse
  181. Effect of antifungal drugs on cytochrome P450 (CYP) 1A2, CYP2D6, and CYP2E1 activities in human liver microsomes
  182. Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine
  183. Combined analysis of germline polymorphisms of p53, GSTM1, GSTT1, CYP1A1, and CYP2E1: relation to the incidence rate of cervical carcinoma
  184. Immunohistochemical demonstration of the expression of CYP2E1 in human breast tumour and non-tumour tissues
  185. Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro
  186. Genetic polymorphisms in cytochrome P450 (CYP) 1A1, CYP1A2, CYP2E1, glutathione S-transferase (GST) M1 and GSTT1 and susceptibility to prostate cancer in the …
  187. Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene
  188. A significantly joint effect between arsenic and occupational exposures and risk genotypes/diplotypes of CYP2E1, GSTO1 and GSTO2 on risk of urothelial carcinoma
  189. CYP2E1 regulation by benzene and other small organic chemicals in rat liver and peripheral lymphocytes
  190. Metabolic oxidation and toxification of N-methylformamide catalyzed by the cytochrome P450 isoenzyme CYP2E1.
  191. Differential Modulation of CYP2E1 Activity by CAMP-Dependent Protein Kinase upon Ser129Replacement
  192. Kinetic characterization of CYP2E1 inhibition in vivo and in vitro by the chloroethylenes
  193. Translational activation of ethanol-inducible cytochrome P450 (CYP2E1) by isoniazid
  194. Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations
  195. Distribution and differential induction of CYP2E1 by ethanol and acetone in the mesocorticolimbic system of rat
  196. Identification and characterization of a mitochondrial targeting signal in rat cytochrome P450 2E1 (CYP2E1)
  197. Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using CYP2E1-/-mice
  198. CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling
  199. Analysis of CYP2E1 polymorphism for the determination of genetic susceptibility to gastric cancer in Koreans
  200. Obesity-induced increase of CYP2E1 activity and its effect on disposition kinetics of chlorzoxazone in Zucker rats
  201. Lung cancer risk in relation to the CYP2E1 Rsa I genetic polymorphism among African-Americans and Caucasians in Los Angeles County.
  202. Polymorphism in CYP1A1 and CYP2E1 genes and susceptibility to leukoplakia in Indian tobacco users
  203. Early Alcoholic Liver Injury: Formation of Protein Adducts with Acetaldehyde and Lipid Peroxidation Products, and Expression of CYP2E1 AND CYP3A
  204. Frequencies of genotypes and alleles of the functional SNPs in CYP2C19 and CYP2E1 in mainland Chinese Kazakh, Uygur and Han populations
  205. CYP1A1 CYP2E1 and GSTM1 polymorphisms are not associated with susceptibility to squamous‐cell carcinoma of the esophagus
  206. Influence of CYP1A1, CYP2E1, GSTM3 and NAT2 genetic polymorphisms in oral cancer susceptibility: results from a case-control study in Rio de Janeiro
  207. Effects of cytochrome P450 (CYP) 2A6 gene deletion and CYP2E1 genotypes on gastric adenocarcinoma
  208. Involvement of CYP2E1 as a low-affinity enzyme in phenacetin O-deethylation in human liver microsomes
  209. Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice
  210. Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH …
  211. Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity
  212. A Novel Polymorphism rs1329149 of CYP2E1 and a Known Polymorphism rs671 of ALDH2 of Alcohol Metabolizing Enzymes Are Associated with Colorectal Cancer …
  213. Association of CYP2E1 and NAT2 gene polymorphisms with chronic obstructive pulmonary disease
  214. CYP2A6 and CYP2E1 polymorphisms in a Brazilian population living in Rio de Janeiro
  215. Microsomal ethanol oxidizing system: transcriptional and posttranscriptional regulation of cytochrome P450, CYP2E1.
  216. Mitochondrial dysfunction by γ-irradiation accompanies the induction of cytochrome P450 2E1 (CYP2E1) in rat liver
  217. Role of CYP2E1 genotypes in susceptibility to colorectal cancer in the Kashmiri population
  218. Acetaldehyde generating enzyme systems: roles of alcohol dehydrogenase, CYP2E1 and catalase, and speculations on the role of other enzymes and processes
  219. Inactivation of stress protein p8 increases murine carbon tetrachloride hepatotoxicity via preserved CYP2E1 activity
  220. Lycopene attenuates alcoholic apoptosis in HepG2 cells expressing CYP2E1
  221. CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90
  222. CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell …
  223. Induction of nicotine-metabolizing CYP2B1 by ethanol and ethanol-metabolizing CYP2E1 by nicotine: summary and implications
  224. Expression of CYP2E1 in human nasopharynx and its metabolic effect in vitro
  225. Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity
  226. Genetic Polymorphisms of ADH1C and CYP2E1 and Risk of Oral Squamous Cell Carcinoma
  227. Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations
  228. CYP2E1 expression in human lymphocytes from various ethnic populations
  229. Association between CYP2E1 polymorphisms and susceptibility to prostate cancer
  230. CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases …
  231. CYP2E1-dependent benzene toxicity: the role of extrahepatic benzene metabolism
  232. The effects of alcohol and diallyl sulphide on CYP2E1 activity in humans: a phenotyping study using chlorzoxazone
  233. Distribution of ADH1B, ALDH2, CYP2E1∗ 6, and CYP2E1∗ 7B genotypes in Turkish population
  234. The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells
  235. Genetic polymorphism of CYP2E1, ADH2, and ALDH2 in Mexican-Americans
  236. Effect of ALDH2 and CYP2E1 Gene Polymorphisms on Drinking Behavior and Alcoholic Liver Disease in Japanese Male Workers
  237. Tandem Repeat Polymorphism of the CYP2E1 Gene: An Association Study With Esophageal Cancer and Lung Cancer
  238. The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone
  239. CYP1A2* 1C, CYP2E1* 5B, and GSTM1 polymorphisms are predictors of risk and poor outcome in head and neck squamous cell carcinoma patients
  240. Polymorphisms in glutathione S‐transferases GSTM1, GSTT1 and GSTP1 and cytochromes P450 CYP2E1 and CYP1A1 and susceptibility to cirrhosis or …
  241. DNA damage and cytotoxicity in pancreatic β-cells expressing human CYP2E1
  242. Cytochrome P4502E1 (CYP2E1) expression in peripheral blood lymphocytes: evaluation in hepatitis C and diabetes
  243. Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the …
  244. Relationship in healthy subjects between CYP2E1 genetic polymorphisms and the 6-hydroxyIation of chlorzoxazone: a putative measure of CYP2E1 activity
  245. Pharmacokinetics of chlorzoxazone in rats with diabetes: induction of CYP2E1 on 6-hydroxychlorzoxazone formation
  246. Significance of genetic polymorphisms at multiple loci of CYP2E1 in the risk of development of childhood acute lymphoblastic leukemia
  247. The effect of isoniazid on CYP2E1-and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney
  248. Immunohistochemical study of CYP2E1 in hepatocellular carcinoma carcinogenesis: examination with newly prepared anti-human CYP2E1 antibody
  249. Human hepatocytes are protected from ethanol-induced cytotoxicity by DADS via CYP2E1 inhibition
  250. Genetic polymorphism of the CYP1A1, CYP2E1, GSTM1 and GSTT1 genes and lung cancer susceptibility in a north Indian population
  251. Cytochrome CYP2E1 phenotyping and genotyping in the evaluation of health risks from exposure to polluted environments
  252. Growth retardation of fetal rats exposed to nicotine in utero: Possible involvement of CYP1A1, CYP2E1, and P‐glycoprotein
  253. Association of GSTM1, CYP1A1 and CYP2E1 genetic polymorphisms with susceptibility to lung adenocarcinoma: A case‐control study in Chinese population
  254. Induction of hepatic CYP2E1 by a subtoxic dose of acetaminophen in rats: increase in dichloromethane metabolism and carboxyhemoglobin elevation
  255. CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking
  256. The impact of CYP2E1 genetic variability on risk assessment of VOC mixtures
  257. Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in rats
  258. Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism
  259. CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism
  260. Global Analysis of Protein− Protein Interactions Reveals Multiple CYP2E1− Reductase Complexes
  261. Differential role of CYP2E1 binders and isoniazid on CYP2E1 protein modification in NADPH-dependent microsomal oxidative reactions: free radical scavenging …
  262. Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity
  263. Polymorphisms of CYP1a1, CYP2E1, GSTM1, GSTT1, and TP53 genes in Amerindians
  264. CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head and …
  265. CYP2E1 Rsa I/Pst I polymorphism is associated with lung cancer risk among Asians
  266. The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes
  267. Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions
  268. Studies on interindividual variations of CYP2E1 using chlorzoxazone as an in vivo probe
  269. A Case–control and a family-based association study revealing an association between CYP2E1 polymorphisms and nasopharyngeal carcinoma risk …
  270. Functional polymorphism in porcine CYP2E1 gene: Its association with skatole levels
  271. Identification of CYP2E1 in marmoset monkey
  272. Effects of diabetes on rabbit kidney and lung CYP2E1 and CYP2B4 expression and drug metabolism and potentiation of carcinogenic activity of N …
  273. Does CYP2E1 play a major role in the aggravation of isoniazid toxicity by rifampicin in human hepatocytes?
  274. Relationship between genetic polymorphisms of metabolizing enzymes CYP2E1, GSTM1 and Kazakh’s esophageal squamous cell cancer in Xinjiang, China
  275. ADH2 and CYP2E1 genetic polymorphisms: risk factors for alcohol-related birth defects
  276. Renal and hepatic accumulation of cadmium and lead in the expression of CYP4F2 and CYP2E1
  277. Ageing is associated with increased expression but decreased activity of CYP2E1 in male Wistar rats
  278. Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity
  279. Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system
  280. Effect of cigarette smoke on hepatic and pulmonary cytochromes P450 in mouse: evidence for CYP2E1 induction in lung
  281. CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese
  282. Effect of fasting and obesity in humans on the 6‐hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity
  283. Benzene-induced genotoxicity in mice in vivo detected by the alkaline comet assay: reduction by CYP2E1 inhibition
  284. Adverse Birth Outcomes Associated with Maternal Smoking and Polymorphisms in the N-Nitrosamine-Metabolizing Enzyme Genes NQO1 and CYP2E1
  285. NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species
  286. Hypomethylation and hypoexpression of human CYP2E1 gene in lung tumors
  287. GSTT1 and CYP2E1 polymorphisms and trihalomethanes in drinking water: effect on childhood leukemia.
  288. Inhibition of CYP2E1 with natural agents may be a feasible strategy for minimizing the hepatotoxicity of ethanol
  289. A High Throughput Screening Assay to Screen for CYP2E1 Metabolism and Inhibition Using a Fluorogenic Vivid® P450 Substrate
  290. Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1
  291. GSTT1, GSTM1 and CYP2E1 genetic polymorphisms in gastric cancer and chronic gastritis in a Brazilian population
  292. A temporal study on the histopathological, biochemical and molecular responses of CCl4-induced hepatotoxicity in CYP2E1-null mice
  293. Effects of Ganoderma lucidum polysaccharide on CYP2E1, CYP1A2 and CYP3A activities in BCG-immune hepatic injury in rats
  294. Expression of CYP2E1 in Human Lung and Kidney during Development and in Full‐Term Placenta: A Differential Methylation of the Gene is Involved in the …
  295. Comparative metabolism and disposition of trichloroethylene in CYP2E1–/–and wild-type mice
  296. Inhibition of cytochrome P450 enzymes participating in p-nitrophenol hydroxylation by drugs known as CYP2E1 inhibitors
  297. Chlorzoxazone as a single sample probe of hepatic CYP2E1 activity in humans
  298. Kupffer cell inactivation alleviates ethanol-induced steatosis and CYP2E1 induction but not inflammatory responses in rat liver
  299. Protective effects of emodin and chrysophanol isolated from marine fungus Aspergillus sp. on ethanol-induced toxicity in HepG2/CYP2E1 cells
  300. Association of combined CYP2E1 gene polymorphism with the risk for esophageal squamous cell carcinoma in Huai’an population, China
  301. Covalent immobilization of recombinant human cytochrome CYP2E1 and glucose-6-phosphate dehydrogenase in alumina membrane for drug screening applications
  302. Promoter function and the role of cytokines in the transcriptional regulation of rabbit CYP2E1 and CYP2E2
  303. Differential effects of diabetes on CYP2E1 and CYP2B4 proteins and associated drug metabolizing enzyme activities in rabbit liver
  304. … exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 …
  305. Relationship between alcoholism and CYP2E1 C/D polymorphism
  306. Polymorphism of metabolizing genes and lung cancer histology: prevalence of CYP2E1 in adenocarcinoma
  307. Differential effects of dietary fatty acids on the regulation of CYP2E1 and protein kinase C in human hepatoma HepG2 cells
  308. Cytochrome P4502E1 (CYP2E1) genetic polymorphism in a case-control study of gastric cancer and liver disease.
  309. Lymphocyte cytochrome P450-CYP2E1 expression in human IDDM subjects
  310. Role of calcium and calcium-activated proteases in CYP2E1-dependent toxicity in HEPG2 cells
  311. Oxidative stress potentiated by diallylsulfide, a selective CYP2E1 inhibitor, in isoniazid toxic effect on rat primary hepatocytes
  312. Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP2E1, GSTM1, and NAT2), drinking habits, histological subtypes, and p53 …
  313. The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin
  314. Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1
  315. Helicobacter pylori infection, but not genetic polymorphism of CYP2E1, is highly prevalent in gastric cancer patients younger than 40 years
  316. Role of CYP2E1 immunoglobulin G4 subclass antibodies and complement in pathogenesis of idiosyncratic drug-induced hepatitis
  317. A negative cooperativity mechanism of human CYP2E1 inferred from molecular dynamics simulations and free energy calculations
  318. Hormone controlled phosphorylation and degradation of CYP2B1 and CYP2E1 in isolated rat hepatocytes
  319. Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue
  320. Genetic polymorphism of the CYP2E1 gene and susceptibility to Parkinson’s disease in Taiwanese
  321. Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity
  322. Differential in vivo effects of α‐naphthoflavone and β‐naphthoflavone on CYP1A1 and CYP2E1 in rat liver, lung, heart, and kidney
  323. cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse CYP2E1
  324. … and CYP2E1 and N‐terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae − role of protein kinase A in the mitochondrial targeting of CYP2E1
  325. CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk: a meta-analysis
  326. Lipopolysaccharide induces CYP2E1 in astrocytes through MAP kinase kinase-3 and C/EBPβ and-δ
  327. Inhibition of urethane-induced genotoxicity and cell proliferation in CYP2E1-null mice
  328. Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1–JNK1 pathway in HepG2 cells
  329. Theoretical study of the mechanism of acetaldehyde hydroxylation by compound I of CYP2E1
  330. Molecular modelling of CYP2E1 enzymes from rat, mouse and man: an explanation for species differences in butadiene metabolism and potential carcinogenicity, and …
  331. The molecular mechanism regulating 24‐hour rhythm of CYP2E1 expression in the mouse liver
  332. Ethanol‐related cytotoxicity catalyzed by CYP2E1‐dependent generation of reactive oxygen intermediates in transduced HepG2 cells
  333. Validation of the (ω-l)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1
  334. The ADH3* 2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men
  335. Interindividual variability of chlorzoxazone 6‐hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms
  336. Impact of CYP2E1 genotype in renal cell and urothelial cancer patients
  337. Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage
  338. Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1
  339. Role of CYP2E1 activity in endoplasmic reticulum ubiquitination, proteasome association, and the unfolded protein response
  340. Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes
  341. Distribution of cytochrome CYP2E1 in murine liver after ethanol and acetone administration
  342. Contribution of CYP2E1 to N-methyl-2-pyrrolidone metabolism
  343. Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration.
  344. Phenobarbital induces monkey brain CYP2E1 protein but not hepatic CYP2E1, in vitro or in vivo chlorzoxazone metabolism
  345. Ethanol-induced oxidative DNA damage and CYP2E1 expression in liver tissue of Aldh2 knockout mice
  346. Modification of CYP2E1 and CYP3A4 activities in haemoglobin E-beta thalassemia patients
  347. Changes of CYP2E1 activity in diabetic rat model
  348. Use of molecular simulation for mapping conformational CYP2E1 epitopes
  349. Ethanol enhanced the genotoxicity of acrylamide in human, metabolically competent HepG2 cells by CYP2E1 induction and glutathione depletion
  350. Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene
  351. The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine
  352. Differential metabolism of acrylonitrile to cyanide is responsible for the greater sensitivity of male vs female mice: role of CYP2E1 and epoxide hydrolases
  353. CYP2E1 expression in bone marrow and its intra-and interspecies variability: approaches for a more reliable extrapolation from one species to another in the risk …
  354. Role of CYP2E1 and saturation kinetics in the bioactivation of thioacetamide: Effects of diet restriction and phenobarbital
  355. Stable expression of human CYP2E1 in Chinese hamster cells: high sensitivity to N, N-dimethylnitrosamine in cytotoxicity testing
  356. Immunological detection of CYP2E1 in fresh rat lymphocytes and its pretranslational induction by fasting
  357. The induction of the human hepatic CYP2E1 gene by interleukin 4 is transcriptional and regulated by protein kinase C
  358. Comparison of genetic polymorphisms of CYP2E1, ADH2, and ALDH2 genes involved in alcohol metabolism in Koreans and four other ethnic groups
  359. Identification of inhibitory component in cinnamon—o-methoxycinnamaldehyde inhibits cyp1a2 and CYP2E1—
  360. Hepatic and pulmonary microsomal benzene metabolism in CYP2E1 knockout mice
  361. … in urea in conjunction with L-arginine metabolism in the liver leads to induction of cytochrome P450 2E1 (CYP2E1): The role of urea in CYP2E1 induction by acute …
  362. Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N‐acetyltransferase in healthy human subjects
  363. Detection of auto-antibodies against cytochrome P4502E1 (CYP2E1) in chronic hepatitis C
  364. CYP2E1-catalyzed oxidation contributes to the sperm toxicity of 1-bromopropane in mice
  365. Protective effects of loquat (Eriobotrya japonica) leaves against ethanol-induced toxicity in HepG2 cells transfected with CYP2E1
  366. Transfected HepG2 cells for evaluation of catechin effects on alcohol-induced CYP2E1 cytotoxicity
  367. Safrole-DNA adducts in human peripheral blood—an association with areca quid chewing and CYP2E1 polymorphisms
  368. Increased bioaccumulation of urethane in CYP2E1-/-versus CYP2E1+/+ mice
  369. Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity
  370. Age-related changes in the protein and mRNA levels of CYP2E1 and CYP3A isoforms as well as in their hepatic activities in Wistar rats. What role for oxidative stress?
  371. Functional CYP2E1 is required for substantial in vivo formation of 2, 5-hexanedione from n-hexane in the mouse
  372. Metabolism of ethyl carbamate by pulmonary cytochrome P450 and carboxylesterase isozymes: involvement of CYP2E1 and hydrolase A
  373. Genetic Repeat Polymorphism in the Regulating Region of CYP2E1: Frequency and Relationship With Enzymatic Activity in Alcoholics
  374. … by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and Rat CYP2A3
  375. Effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on toluene metabolism in humans
  376. Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model
  377. Investigation of bioactivation and toxicity of styrene in CYP2E1 transgenic cells
  378. Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co‐expressing HCV core protein and CYP2E1
  379. Acute ethanol pretreatment increases FAS-mediated liver injury in mice: role of oxidative stress and CYP2E1-dependent and-independent pathways
  380. DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms significantly contribute to the risk of development of childhood …
  381. Do Endogenous Volatile Organic Chemicals Measured in Breath Reflect and Maintain CYP2E1 Levelsin Vivo?
  382. XRCC1 and CYP2E1 Polymorphisms as Susceptibility Factors of Plasma Mutant p53 Protein and Anti-p53 Antibody Expression in Vinyl Chloride …
  383. Evidence of association of the CYP2E1 genetic polymorphism with micronuclei frequency in human peripheral blood
  384. Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation)
  385. CYP2E1 mRNA expression, genetic polymorphisms in peripheral blood lymphocytes and liver abnormalities in Chinese VCM-exposed workers
  386. Role of CYP1A2 and CYP2E1 in the pentoxifylline ciprofloxacin drug interaction
  387. Comparison of the susceptibility of wild-type and CYP2E1 knockout mice to the hepatotoxic and pneumotoxic effects of styrene and styrene oxide
  388. High inducibility of mouse renal CYP2E1 gene by tobacco smoke and its possible effect on DNA single strand breaks
  389. Effect of the CYP2E1 genotype on vinyl chloride monomer-induced liver fibrosis among polyvinyl chloride workers
  390. Gene–environmental interactions between alcohol-drinking behavior and ALDH2 and CYP2E1 polymorphisms and their impact on micronuclei frequency in human …
  391. Duration of cytochrome P-450 2E1 (CYP2E1) inhibition and estimation of functional CYP2E1 enzyme half-life after single-dose disulfiram administration in humans
  392. Induction of CYP2E1 activity in liver transplant patients as measured by chlorzoxazone 6‐hydroxylation
  393. Diallyl sulfide inhibition of CYP2E1 does not rescue diabetic rats from thioacetamide-induced mortality
  394. Pulmonary bioactivation of trichloroethylene to chloral hydrate: relative contributions of CYP2E1, CYP2F, and CYP2B1
  395. The 2006 bernard B. Brodie award lecture: CYP2E1
  396. Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake
  397. Effects of genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 on the urinary levels of 1-hydroxypyrene and 2-naphthol in aircraft maintenance workers
  398. Genetic polymorphisms of CYP2E1 and GSTM1 in a Thai population
  399. DLPC attenuates alcohol-induced cytotoxicity in HepG2 cells expressing CYP2E1
  400. Role of polymorphic CYP2E1 and CYP2D6 genes in NNK-induced chromosome aberrations in cultured human lymphocytes
  401. A comparison of substrate dynamics in human CYP2E1 and CYP2A6
  402. S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice
  403. Expression of CYP2E1 by human monocyte‐derived macrophages
  404. CYP2E1 polymorphisms and gene–environment interactions in the risk of upper aerodigestive tract cancers among Indians
  405. NAT2, CYP2C9, CYP2C19, and CYP2E1 genetic polymorphisms in anti-TB drug-induced maculopapular eruption
  406. Role of CYP2E1 in the pathogenesis of alcoholic liver disease: modifications by cAMP and ubiquitin-proteasome pathway
  407. Spectrophotometric analysis of human CYP2E1-catalyzed p-nitrophenol hydroxylation
  408. Cervical cancer and CYP2E1 polymorphisms: implications for molecular epidemiology
  409. Inactivation of hepatic CYP2E1 by an epoxide of diallyl sulfone
  410. Insertion polymorphism of CYP2E1 and urinary N-methylformamide after N, N-dimethylformamide exposure in Japanese workers
  411. Effect of exposure to benzo [a] pyrene on SODs, CYP1A1/1A2-and CYP2E1 immunopositive proteins in the blood clam Scapharca inaequivalvis
  412. Ethanol-mediated transplacental induction of CYP2E1 in fetal rat liver
  413. Breaking self-tolerance toward cytochrome P4502E1 (CYP2E1) in chronic hepatitis C: possible role for molecular mimicry
  414. Cytochrome P450 2E1 (CYP2E1)-dependent production of a 37-kDa acetaldehyde–protein adduct in the rat liver
  415. Ethanol intake and ethanol-induced locomotion and locomotor sensitization in CYP2E1 knockout mice
  416. Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratios
  417. Genotype and allele frequencies of polymorphic cytochromes P450 CYP1A2 and CYP2E1 in Mexicans
  418. CYP1A1, CYP2E1, GSTM1, GSTT1, GSTP1, and TP53 polymorphisms: do they indicate susceptibility to chronic obstructive pulmonary disease and non-small-cell …
  419. Effects of dietary fat composition on activities of the microsomal ethanol oxidizing system and ethanol‐inducible cytochrome P450 (CYP2E1) in the liver of rats …
  420. Use of the CYP2E1 genotype and phenotype for the biological monitoring of occupational exposure to styrene
  421. In vivo and in vitro characterization of chlorzoxazone metabolism and hepatic CYP2E1 levels in African Green monkeys: induction by chronic nicotine treatment
  422. Proteasome inhibition potentiates CYP2E1‐mediated toxicity in HepG2 cells
  423. Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure
  424. Adenovirus-mediated expression of Cu/Zn-or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity
  425. CYP2E1 G1532C, NQO1 Pro187Ser, and CYP1B1 Val432Leu polymorphisms are not associated with risk of squamous cell carcinoma of the head and neck
  426. CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling
  427. Malotilate, a hepatoprotectant, suppresses CYP2E1 expression in rats
  428. Role of mouse CYP2E1 in the O-hydroxylation of p-nitrophenol: comparison of activities in hepatic microsomes from CYP2E1 (-/-) and wild-type mice
  429. Pulsatile blood alcohol and CYP2E1 induction during chronic alcohol infusions in rats
  430. … dehydrogenase 2, cytochrome p450 2E1 for liver cancer risk in HCV antibody-positive japanese patients and the variations of CYP2E1 mRNA expression levels in the …
  431. Use of CYP2E1‐transfected human liver cell lines in elucidating the actions of ethanol
  432. In vivo CYP2E1 phenotyping as a new potential biomarker of occupational and experimental exposure to benzene
  433. Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression
  434. Genetic polymorphisms of the CYP2E1 gene do not contribute to oral cancer susceptibility in south Indians
  435. Phenotype distribution and gender-related differences of CYP2E1 activity in a Chinese population
  436. Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1
  437. Influence of genetic admixture on polymorphisms of drug‐metabolizing enzymes: Analyses of mutations on NAT2 and CYP2E1 genes in a mixed Hispanic …
  438. Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells
  439. Association Studies of Polymorphisms of CYP2E1 Gene in Alcoholics with Cirrhosis, Antisocial Personality, and Normal Controls
  440. Transcriptional and posttranscriptional regulation of CYP2E1, an N-nitrosodimethylamine demethylase.
  441. Association of CYP2E1, GST and mEH genetic polymorphisms with urinary acrylamide metabolites in workers exposed to acrylamide
  442. Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity
  443. Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: Role of CYP2E1 and TNF-α and activation of JNK and P38 MAP kinase
  444. Role of CYP2E1 in deramciclane metabolism
  445. S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury
  446. The influence of genetic polymorphism of CYP2E1 on the development of alcohol liver cirrhosis
  447. p53 mutation spectrum in relation to GSTM1, CYP1A1 and CYP2E1 in surgically treated patients with non-small cell lung cancer.
  448. Evidence for a tissue-specific induction of cutaneous CYP2E1 by dexamethasone
  449. Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes
  450. Genetic Polymorphisms of CYP2E1 and Risk of Colorectal Adenomas in the Self Defense Forces Health Study
  451. CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls
  452. The effect of lycopene on the total cytochrome P450, CYP1A2 and CYP2E1
  453. Chlorzoxazone metabolism by winter flounder liver microsomes: evidence for existence of a CYP2E1-like isoform in teleosts
  454. Role of CYP2E1 in the mouse model of MPTP toxicity
  455. Genetic polymorphism of CYP2E1 and digestive tract alcohol damage among Polish individuals
  456. CYP2E1 genotyping in renal cell/urothelial cancer patients in comparison with control populations.
  457. Genetic polymorphisms of CYP2E1, GSTT1, GSTP1, GSTM1, ALDH2, and ODC and the risk of advanced precancerous gastric lesions in a Chinese population
  458. Transgenic plants of Petunia hybrida harboring the CYP2E1 gene efficiently remove benzene and toluene pollutants and improve resistance to formaldehyde
  459. Induction of CYP2B and CYP2E1 in precision-cut rat liver slices cultured in defined medium
  460. Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-κB …
  461. Mammalian cytochrome CYP2E1 triggered differential gene regulation in response to trichloroethylene (TCE) in a transgenic poplar
  462. CYP2E1 polymorphism, cigarette smoking, p53 expression, and survival in non-small cell lung cancer: a long term follow-up study
  463. Short-term treatment with alcohols causes hepatic steatosis and enhances acetaminophen hepatotoxicity in CYP2E1 (-/-) mice
  464. Phosphorylation of cytochrome P4502E1 (CYP2E1) by calmodulin dependent protein kinase protein kinase C and cAMP dependent protein kinase
  465. PI3K inhibitors reverse the suppressive actions of insulin on CYP2E1 expression by activating stress-response pathways in primary rat hepatocytes
  466. In vitro metabolism of styrene to styrene oxide in liver and lung of CYP2E1 knockout mice
  467. Dietary lipids affect human ethanol-inducible CYP2E1 gene expression in vivo in mononuclear cells
  468. Independent and combined effects of ethanol self-administration and nicotine treatment on hepatic CYP2E1 in African green monkeys
  469. … of human prenatal biosynthesis of all-trans-retinoic acid by ethanol, ethanol metabolites, and products of lipid peroxidation reactions: a possible role for CYP2E1
  470. Gene Structure and Multiple Regulations of the Ethanol-Inducible Cytochrome P45O2E1 (CYP2E1) Subfamily
  471. Role of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells
  472. Panax vietnamensis protects mice against carbon tetrachloride-induced hepatotoxicity without any modification of CYP2E1 gene expression
  473. Study on the association between genetic polymorphism of CYP2E1, GSTM1 and susceptibility of lung cancer
  474. A multiplex-PCR/RFLP procedure for simultaneous CYP2E1, mEH and GSTM1 genotyping
  475. Lycopene attenuates arachidonic acid toxicity in HepG2 cells overexpressing CYP2E1
  476. APOE and CYP2E1 polymorphisms, alcohol consumption, and Parkinson’s disease in a Japanese population
  477. Epoxide formation from diallyl sulfone is associated with CYP2E1 inactivation in murine and human lungs
  478. D2-receptor-linked signaling pathways regulate the expression of hepatic CYP2E1
  479. Metabolic activation of o-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1
  480. Expression and activity of CYP2E1 in circulating lymphocytes are not altered in diabetic individuals
  481. Modification effects of GSTM1, GSTT1 and CYP2E1 polymorphisms on associations between raw salted food and incomplete intestinal metaplasia in a high‐risk …
  482. Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques
  483. Depression of glutathione content, elevation of CYP2E1-dependent activation, and the principal determinant of the fasting-mediated enhancement of 1, 3-dichloro-2 …
  484. Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1, 3‐dimethyluric …
  485. Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in …
  486. Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells
  487. No significant expression of CYP2E1 in rat liver stellate cells
  488. CYP2E1 and clinical features in alcoholics
  489. Comparison of chlorzoxazone one-sample methods to estimate CYP2E1 activity in humans
  490. Acetaminophen alters microsomal ryanodine Ca2+ channel in HepG2 cells overexpressing CYP2E1
  491. No Association between Polymorphisms in CYP2E1, GSTM1, NAT1, NAT2 and the Risk of Gastric Adenocarcinoma in the European Prospective Investigation into …
  492. The effect of isoniazid containing regimen on CYP2E1 during antituberculosis therapy.
  493. A Haplotype Analysis of CYP2E1 Polymorphisms in Relation to Alcoholic Phenotypes in Mexican Americans
  494. A reaction network model for CYP2E1-mediated metabolism of toxicant mixtures
  495. Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1
  496. Cytochrome b5 reductase and cytochrome b5 support the CYP2E1-mediated activation of nitrosamines in a recombinant Ames test
  497. Overexpression of CYP2E1 enhances sensitivity of hepG2 cells to fas-mediated cytotoxicity
  498. INFLUENCE OF GENETIC ADMIXTURE ON POLYMORPHISMS OF ALCOHOL-METABOLIZING ENZYMES: ANALYSES OF MUTATIONS ON THE CYP2E1, ADH2, ADH3 AND …
  499. Liver nuclear and microsomal CYP2E1-mediated metabolism of xenobiotics in rats chronically drinking an alcohol-containing liquid diet
  500. Effect of CYP2E1 induction by ethanol on the immunotoxicity and genotoxicity of extended low-level benzene exposure
  501. Role of nitric oxide and nuclear factor-κB in the CYP2E1 potentiation of tumor necrosis factor α hepatotoxicity in mice
  502. Identification of sequences responsible for intracellular targeting and membrane binding of rat CYP2E1 in yeast
  503. Suppression of cytochrome P450 2E1 promoter activity by interferon-γ and loss of response due to the-71G> T nucleotide polymorphism of the CYP2E1* 7B allele
  504. Identification and functional analysis of a novel human CYP2E1 far upstream enhancer
  505. Rifampicin suppresses hepatic CYP2E1 expression and minimizes DNA injury caused by carbon tetrachloride in perivenular hepatocytes of mice
  506. Inhibition of CYP2E1 activity does not abolish pulsatile urine alcohol concentrations during chronic alcohol infusions
  507. Molecular cloning and sequence analysis of hamster CYP2E1
  508. Relationship between genetic polymorphism of CYP2E1 and ALDH2, and possible susceptibility to alcoholism
  509. … mechanism of Wu-Zi-Yan-Zong-Wan, a traditional Chinese herbal formula, against alcohol-induced oxidative damage in CYP2E1 cDNA-transfected HepG2 (E47) …
  510. … overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1
  511. Effects of steady-state lasofoxifene on CYP2D6-and CYP2E1-mediated metabolism
  512. [12] Chlorzoxazone: An in vitro and in vivo substrate probe for liver CYP2E1
  513. CYP2E1-dependent bioactivation of 1, 1-dichloroethylene in murine lung: formation of reactive intermediates and glutathione conjugates
  514. Modulation of mouse P450 isoforms CYP1A2, CYP2B10, CYP2E1, and CYP3A by the environmental chemicals mirex, 2, 2-bis (p-chlorophenyl)-1, 1-dichloroethylene …
  515. Lack of cytochrome P450 2E1 (CYP2E1) induction in the rat liver by starvation without coprophagy
  516. Influence of GSTs, CYP2E1 and mEH polymorphisms on 1, 3-butadiene-induced micronucleus frequency in Chinese workers
  517. Influence of GSTT1, mEH, CYP2E1 and RAD51 polymorphisms on diepoxybutane-induced SCE frequency in cultured human lymphocytes
  518. Tightly regulated and inducible expression of rabbit CYP2E1 using a tetracycline-controlled expression system
  519. Striking LD50 variation associated with fluctuations of CYP2E1-positive cells in hepatic lobule during chronic CCl4 exposure in mice
  520. Expression of cytochrome P450 enzymes CYP1A1, CYP1B1, CYP2E1 and CYP4B1 in cultured transitional cells from specimens of the human urinary tract and from …
  521. Isozyme-selective metabolism of ethyl carbamate by cytochrome P450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes in murine liver microsomes
  522. … of the accumulation of acetaldehyde from ethanol in human prenatal cephalic tissues: evaluation of the relative contributions of CYP2E1, alcohol dehydrogenase, and …
  523. CYP2E1 and CYP3A1/2 gene expression is not associated with the ursodeoxycholate effect on ethanol-induced lipoperoxidation
  524. CYP2E1 inhibition enhances mallory body formation
  525. XRCC1, CYP2E1 and ALDH2 genetic polymorphisms and sister chromatid exchange frequency alterations amongst vinyl chloride monomer-exposed polyvinyl …
  526. Cytochrome b5 coexpression increases the CYP2E1-dependent mutagenicity of dialkylnitrosamines in methyltransferase-deficient strains of Salmonella typhimurium
  527. Effect of disulfiram‐mediated CYP2E1 inhibition on the disposition of vesnarinone
  528. Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity
  529. CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells
  530. Induction of brain CYP2E1 changes the effects of ethanol on dopamine release in nucleus accumbens shell
  531. The role of phosphatidylinositol 3-kinase, Src kinase, and protein kinase A signaling pathways in insulin and glucagon regulation of CYP2E1 expression
  532. Voglibose potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen by inducing CYP2E1 in rats
  533. Administration of the tris salt of α-tocopheryl hemisuccinate inactivates CYP2E1, enhances microsomal α-tocopherol levels and protects against carbon tetrachloride …
  534. Influence of selected inhibitors on the metabolism of the styrene metabolite 4-vinylphenol in wild-type and CYP2E1 knockout mice
  535. Lack of common mutation in the alfa-subunit of the mitochondrial trifunctional protein and the polymorphism of CYP2E1 in three Japanese women with acute fatty liver …
  536. Induction of CYP1A1 and CYP2E1 in rat liver by histamine: binding and kinetic studies
  537. Cytochrome P4502E1 (CYP2E1) Genetic Polymorphisms in a Lebanese Population: Frequency Distribution and Association with Morbid Diseases
  538. CYP1A1 and CYP2E1 polymorphism frequencies in a large Brazilian population
  539. THE EFFECTS OF THE ALDH2*1/2, CYP2E1 C1/C2 AND C/D GENOTYPES ON BLOOD ETHANOL ELIMINATION
  540. Noninvolvement of CYP2E1 in the (ω-1)-hydroxylation of fatty acids in rat kidney microsomes
  541. Effect of total alkaloids of Rubus alceaefolius poiron on gene expressions of CYP2E1 and CYP3A1 in rats with acute liver injury
  542. Watercress has no importance for the elimination of ethanol by CYP2E1 inhibition
  543. Inhibition of rat hepatic CYP2E1 by quinacrine: molecular modeling investigation and effects on 4-(methyl nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced …
  544. Undernutrition during hyperoxic exposure induces CYP2E1 in rat liver
  545. Transcriptional activity of the tandem repeat polymorphism in the 5′‐flanking region of the human CYP2E1 gene
  546. Trifluoroacetylated adducts in spermatozoa, testes, liver and plasma and CYP2E1 induction in rats after subchronic inhalatory exposure to halothane
  547. A polymorphism in the 5′-flanking region of the CYP2E1 gene and elevated lung adenocarcinoma risk in a Japanese population
  548. Polymorphisms of the CYP1A1, CYP2E1 and XRCC1 genes and cancer risk in a Southern Italian population: a case–control study
  549. CYP2E1 level in rat liver injured by the interaction between carbon tetrachloride and chloroform
  550. Serum autoantibodies against cytochrome P450 2E1 (CYP2E1) predict severity of necroinflammation of recurrent hepatitis C
  551. Association of CYP2E1 of PON2311 polymorphisms in neonates with preterm
  552. Role of CYP2E1 in ketone-stimulated insulin release in pancreatic B-cells
  553. Relative roles of CYP2E1 and CYP1A2 in mouse uroporphyria caused by acetone
  554. Extrahepatic metabolism by CYP2E1 in PBPK modeling of lipophilic volatile organic chemicals: impacts on metabolic parameter estimation and prediction of dose …
  555. Use of Duplex PCR-CTPP Methods for CYP2E1 RsaI/IL-2 T-330G and IL-1B C-31T/TNF-A T-1031C Polymorphisms
  556. Examination of a CYP2E1 repeat polymorphism in a monkey model of alcohol abuse
  557. CYP2E1 overexpression up-regulates both non-specific δ-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1
  558. Metabolism and toxicity of the styrene metabolite 4-vinylphenol in CYP2E1 knockout mice
  559. Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells
  560. Urinary excretion of 6‐hydroxychlorzoxazone as an index of CYP2E1 activity
  561. Cloning and expression of rat CYP2E1 in Saccharomyces cerevisiae: Detection of genotoxicity of N‐alkylformamides
  562. Role of the Genetic Polymorphisms in the 5′‐Flanking Region for Transcriptional Regulation of the Human CYP2E1 Gene
  563. Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and …
  564. Conformational anti‐cytochrome P4502E1 (CYP2E1) auto‐antibodies contribute to necro‐inflammatory injury in chronic hepatitis C
  565. Relation of GSTP1 and CYP2E1 polymorphisms with susceptibility to acute leukemia
  566. Decreased CYP2E1 mRNA expression in human leucocytes in patients with fibrotic and inflammatory lung diseases
  567. ALDH2 and CYP2E1 genotypes, urinary acetaldehyde excretion and the health consequences in moderate alcohol consumers
  568. The NH2-terminal region of rabbit CYP2E1 is not essential for interaction with NADPH-cytochrome P450 reductase
  569. Effect of high‐dose aspirin on CYP2E1 activity in healthy subjects measured using chlorzoxazone as a probe
  570. Genetic variation in the temperature dependence of liver microsomal CYP2E1 activity, within and between species of the viviparous fish Poeciliopsis
  571. Insertional polymorphism of the CYP2E1 gene in infiltrative pulmonary tuberculosis in populations of Bashkortostan Republic
  572. Cryopreserved porcine hepatocytes: expression and induction of cytochrome P450, isoform CYP2E1
  573. Comparison of levels of cytochromes P‐450, CYP1A2, CYP2E1, and their related monooxygenase activities in human surgical liver samples
  574. Modulation of ethanol-mediated CYP2E1 induction by clofibrate and L-carnitine in rat liver
  575. The effect of endotoxin on hepatocyte nuclear factor 1 nuclear protein binding: potential implications on CYP2E1 expression in the rat
  576. Effect of CYP2E1 polymorphism on DNA stability and lung cancer susceptibility
  577. Area Under the Plasma Concentration–Time Curve of Inorganic Fluoride Following Sevoflurane Anesthesia Correlates with CYP2E1 mRNA Level in Mononuclear …
  578. Identification of a 16-nucleotide sequence that mediates post-transcriptional regulation of rat CYP2E1 by insulin
  579. Fetal and maternal CYP2E1 genotypes and the risk of nonsyndromic oral clefts
  580. Bioactivation of 1, 1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes
  581. Exacerbation of benzene pneumotoxicity in connexin 32 knockout mice: enhanced proliferation of CYP2E1-immunoreactive alveolar epithelial cells
  582. Comparison of cytochrome P4502E1 (CYP2E1) activity and hepatic and lymphocyte mRNA expression in patients with chronic hepatitis C
  583. IL-4-mediated transcriptional regulation of human CYP2E1 by two independent signaling pathways
  584. Phorbol ester induces CYP2E1 in astrocytes, through a protein kinase C‐and tyrosine kinase‐dependent mechanism
  585. Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity
  586. Polymorphism of the 5′‐Flanking Region of the CYP2E1 Gene: An Association Study With Alcoholism
  587. Activity of immobilised rat hepatic microsomal CYP2E1 using alumina membrane as a support
  588. Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1
  589. Isolation of the mouse cytochrome P450J (CYP2E1) cDNA and its reciprocal testosterone regulation in kidney and liver
  590. Hepatotoxicity Mediated by Pyrazole (CYP2E1) Plus TNF-α Treatment Occurs in jnk2−/− but not in jnk1−/− Mice
  591. A comparison of the inhibitory effects of four volatile anaesthetics on the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits
  592. Contribution of the ALDH2 and CYP2E1 genes to flushing response and drinking patterns in Japanese healthy volunteers
  593. Assessment of frequencies of lifestyle factors and polymorphisms of drug-metabolizing enzymes (NAT2, CYP2E1) in human hepatocellular carcinoma (HCC) patients …
  594. Upregulation of CYP2E1 and cyp3a activities in histamine-deficient histidine decarboxylase gene targeted mice
  595. Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1, 3-dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat
  596. Comparison of the polymorphic regions of the cytochrome P450 CYP2E1 gene of humans and patas and cynomolgus monkeys
  597. Cytochrome p-450-mediated differential oxidative modification of proteins: albumin, apolipoprotein E, and CYP2E1 as targets
  598. Activation of alkylhydrazines to free radical intermediates by ethanol-inducible cytochrome P-4502E1 (CYP2E1)
  599. Insertion Polymorphism of the CYP2E1 gene in patients with infiltrative pulmonary tuberculosis from Bashkortostan
  600. Dichloroacetic acid treatment increases hepatic CYP2E1 in male and female rats
  601. Altered ethylbenzene-mediated hepatic CYP2E1 expression in growth hormone-deficient dwarf rats
  602. Polymorphisms of the cytochrome P450 (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) genes in cystic fibrosis and chronic respiratory disease
  603. … , Scrophularia ningpoensis, Asparagus cochinchinensis and Ophiopogon japonicas on contents of CYP450 and activities of CYP3A, CYP2E1 and CYP1A2 in rat
  604. Genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fishes Poeciliopsis occidentalis and Poeciliopsis lucida
  605. Diminished CYP2E1 expression and formation of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1, 1-dichloroethylene epoxide, in murine lung tumors
  606. Effect of 1-aminobenzotriazole on the in vitro metabolism and single-dose pharmacokinetics of chlorzoxazone, a selective CYP2E1 substrate in Wistar rats
  607. The genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fish Poeciliopsis
  608. Bioactivation of 1, 1-dichloroethylene by CYP2E1 and CYP2F2 in murine lung
  609. Effects of chlorinated aliphatic hydrocarbons on the fidelity of cell division in human CYP2E1 expressing cells
  610. Abnormal liver function associated with polymorphism of GSTT1, GSTM1 and CYP2E1 in workers exposed to N, N-dimethylformamide
  611. CYP2E1–Biochemical and Toxicological Aspects and Role in Alcohol-Induced Liver Injury
  612. Case-control study of the polymorphisms of CYP2E1-RsaⅠ and STT1 genes and susceptibility to pancreatic cancer
  613. Genetic polymorphisms of alcohol inducible CYP2E1 in Turkish population
  614. Expression of human CYP2E1 in insect cells using bac-to-bac expression system
  615. A Case-control study on effects of genetic polymorphisms of GSTM1, GSTT1, CYP1A1 and CYP2E1 on risk of lung cancer
  616. Glucose inhibition of the induction of CYP2E1 mRNA expression by ethanol in FGC-4 cells
  617. Effect of methacrylonitrile on cytochrome P-450 2E1 (CYP2E1) expression in male F344 rats
  618. … of liver microsomal 7-ethoxycoumarin O-deethylation and chlorzoxazone 6-hydroxylation activities in Japanese and Caucasian subjects genotyped for CYP2E1 gene
  619. No linkage of the cytochrome P-450IIE1 (CYP2E1) C1/C2 polymorphism to schizophrenia
  620. Antibodies against CYP2E1 after exposure to 1, 1, 1-trifluoroethane and 1, 1, 1, 2-tetrafluoroethane
  621. Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5′-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR)
  622. Immunohistochemical Detection of CYP2E1 and 2-S-Glutathionyl Acetate in Murine Lung Tumors: Diminished Formation of Reactive Intermediates of 1,1 …
  623. CYP2E1 genotypes and serum LAP in Japanese alcoholics
  624. Genetic polymorphisms of CYP2E1
  625. Non-positive autoimmune responses against CYP2E1 in refrigeration mechanics exposed to halogenated hydrocarbons
  626. Development of a non-high pressure liquid chromatography assay to determine [14C] chlorzoxazone 6-hydroxylase (CYP2E1) activity in human liver microsomes
  627. The colorectal cancer risk of meat intake, smoking, and CYP2E1 polymorphisms: the comparison of colorectal cancer patients with controls
  628. Genetic Polymorphism of Alcohol Metabolizing Enzymes, CYP2E1
  629. Relationship between CYP2E1 polymorphism and increase of ALT activity during therapy of patients with pulmonary tuberculosis
  630. Halothane inhalation inhibits the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits
  631. Analysis of CYP2E1 and GSTM1 polymorphisms for the determination of genetic susceptibility to Korean patients with colon cancer
  632. Inactivation of cytochrome P-450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes by vinyl carbamate in murine pulmonary microsomes
  633. Antibiotic furazolidone induces CYP1A but not CYP2E1 subfamily in rat liver
  634. Effect of starvation and acetone on the enzyme systems of biotransformation and toxicity of xenobiotics–CYP2E1 substrates in rats
  635. Comparative analysis of binding affinities between styrene and mammalian CYP2E1 by bioinformatics approaches
  636. Study of the fragmentation mechanism of protonated 6-hydroxychlorzoxazone: application in simultaneous analysis of CYP2E1 activity with major human cytochrome …
  637. Gene CYP2E1 expression in mouse liver cells exposed to low-dose radiation
  638. Interaction of polymorphisms of CYP2E1 and environmental risk factors in gastric cancer
  639. Effect of Genetic Polymorphisms of CYP2E1 and ALDH2 on the Relationship between the Levels of Urinary 8-Hydroxydeoxyguanosine and t, t-Muconic Acid
  640. Trimethadione N-demethylation by rat liver CYP2E1 in vitro.
  641. Correlation analyses of ALDH2 and CYP2E1 genetic polymorphism with personality
  642. Variations in expression of CYP2E1 and COUP-TF1 proteins between Large White and Duroc cross-breeds
  643. GYKI-47261, a new AMPA [2-amino-3-(3-hydroxymethylisoxazole-4-yl) propionic acid] antagonist, is a CYP2E1 inducer
  644. Research on the relationship between ALDH2 and CYP2E1 gene polymorphism and alcoholic liver disease in Han people
  645. Differential expression of cytochrome P4502E1 (CYP2E1) in Morris hepatomas and livers of tumor bearing rats.
  646. A novel lipopolysaccharide‐modulated Jun binding repressor in intron 2 of CYP2E1
  647. Association analysis of alcohol metabolizing enzymes ADH1B, ADH7, CYP2E1 gene polymorphism with risk for coronary atherosclerosis
  648. Identification of polymorphisms in CYP2E1 gene and association analysis among chronic HBV patients
  649. Increase expression of CYP2E1 mRNA after methamphetamine administration in rats
  650. The role of CYP2E1 in the protection of garlic oil’s from n-hexane-induced neurotoxicity
  651. Pulmonary bioactivation of 1, 1-dichloroethylene is associated with CYP2E1 levels in A/J, CD-1, and C57BL/6 mice
  652. Ethanol-induction of cytochrome P450 2A5: permissive role for CYP2E1
  653. Characterization of a dietary ethanol protocol for CYP2E1 induction in the CD-1 mouse without evident hepatic toxicity or genotoxicity
  654. A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1
  655. Cytochemical Localization of the Acetone-lnducible Cytochrome P-450 Isoform, CYP2E1 in Murine Colonic Epithelium
  656. A study for regulation of ethanol-inducible P450 (CYP2E1) on CCl4-induced hepatic damage
  657. Associations of Rsa I polymorphism at the 5’flanking region of CYP2E1 and PON2 148 polymorphism in neonates with preterm delivery
  658. Effect of sulfur dioxide inhalation on CYP2B1/2 and CYP2E1 in rat liver and lung
  659. Genetic polymorphism of human CYP2E1: new allels detected in exons and exon-intron junctions
  660. Relationship between alcoholism and CYP2E1 genotypes
  661. A case control study on the impact of CYP2E1 and GST-M1 polymorphisms on the risk of lung cancer
  662. Preliminary effects of alcohol and Curcuma longa upon CYP2E1 and hematotoxicity in benzene-induced mice
  663. Association of genetic polymorphisms of aldehyde dehydrogenase II and CYP2E1 and clinical characteristics of patients with alcohol dependence
  664. Downregulation of the CYP2E1 ameliorates oxidative stress and apoptosis
  665. Interaction between genetic polymorphisms of CYP2E1 & NAT1 and smoking in lung cancer development (Preliminary report)
  666. Human CYP2E1 developmental expression: a role in fetal and pediatric susceptibility to toxicants?
  667. Effects of environmental carcinogens and genetic polymorphisms of CYP2E1 and NAT2 on gastric carcinogenesis
  668. Effects of Purified Glycerol from Biodiesel on Cyp1a1 and CYP2E1 Expressions in CBA/CA Mice
  669. Fast CYP2E1 genotyping using automated fluorescent detection.
  670. Association of CYP2E1, NQO1 and GST genetic polymorphisms with risk of acute lymphoblastic leukemia in turkish children
  671. Ruthenium red protects HepG2 cells overexpressing CYP2E1 against acetaminophen cytotoxicity
  672. CYP2E1 competes with CYP2B4 for limited NADPH‐Cytochrome P450 Reductase
  673. Expression and regulation of cytochrome P450 CYP2E1 in the minipig
  674. Effect of TFHL on expression of CYP2E1 in liver tissue of rats with NASH.
  675. Effects of ginsenoside Rd and Panax ginseng extract on Cyp1a, Cyp2b, Cyp2c, CYP2E1, and Cyp3a activities in C57BL/6JNarl mice
  676. The research on the relationship between CD44, CYP2E1 genetic polymorphisms and esophageal cancer
  677. Action-mechanisms of Genetic Polymorphism in the CYP2E1 on Susceptibility to Polycyclic Aromatic Hydrocarbons
  678. CYP1A1, CYP2E1 and gastric cancer risk in a high-incidence Colombian population
  679. Ontogeny of Rat CYP2E1 and CYP1A2: A Characterization and
  680. Effects of mitomycin (MMC) and {gamma}-ray irradiation on cytochrome p450 content and activities of CYP2B1 and CYP2E1 in rats
  681. The modeling of interactions of the CYP2E1 isoform of human cytochrome P450 with substrates
  682. Identification of CYP2E1-dependent genes involved in carbon tetrachloride-induced hepatotoxicity
  683. Evidence for the Existence of Two Human CYP2E1 cDNAs Using Different Polyadenylation Signals
  684. Functional polymorphism of CYP2E1 gene and alcohol use disorders in a Tibetan population.
  685. The ethanol elimination pharmacokinetics–the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism
  686. Differential expression profile of cytochrome p450 2E1 (CYP2E1) related genes associated with carbon tetrachloride-induced hepatotoxicity
  687. Effect of total saikosaponins on the intestinal first-pass effect and liver Cyp3a, CYP2E1
  688. Relationship between gene polymorphism of CYP2E1, CYP1A1, IL-4 and medicamentosa-like dermatitis induced by trichloroethylene
  689. High dose lycopene supplementation increases hepatic CYP2E1 protein and TNF‐α expression in alcohol fed rats
  690. The ethanol elimination pharmacokinetics–the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism
  691. Silibinin inhibits CYP2E1‐dependent ethanol metabolism, oxidative stress and cell proliferation in a rat model of hepatocellular carcinoma (HCC)
  692. Opposite effects of isoniazid and fasting on the expression of CYP2E1 protein and mRNA in house musk shrew (Suncus murinus)
  693. Computational docking studies of nitroanisoles and nitrophenols with CYP2E1
  694. ALDH and CYP2E1 Single Nucleotide Polymorphism Distribution in Korean
  695. Role of CYP2E1 in Hepatocarcinogenesis and Hepatotoxicity
  696. An investigation of CYP2E1 phenotype determination utilizing modeling and simulation studies
  697. Formation of Multiple CYP2E1 Complexes Affects Activity
  698. Regulation of CYP2E1 and Tissue Protection Effect of CYP2E1 Inhibitor
  699. Mapping of pig CYP2E1 to SSC14
  700. ALDH and CYP2E1 Single Nucleotide Polymorphism Distribution in Korean
  701. CYP2E1 mutation associated with increased chlorzoxazone (CZ) metabolic ability
  702. Alcohol, Nicotine and Genetic Variation Influence CYP2E1
  703. Different CYP2E1 genotypes and alcoholic liver disease.
  704. Establishment and toxicological application of a cell line expressing human CYP2E1
  705. The Toxicological Mechanism Of Styrene In CYP2E1 Transgenic Cells
  706. Effect of CYP2E1 Ras I genotypes on CYP2E1 enzyme activity and DNA damage induced by phenol in immortalized human lymphocytes
  707. Effects of environmental factors on extrahepatic CYP2E1 gene expression in mice
  708. Molecular Evidence for the Presence of CYP2E1 Retropseudogene in Human Genome
  709. Role Of Mouse CYP2E1 In The O-Hydroxylation Of P-Nitrophenol: Comparison Of Activities In CYP2E1 (-/-) And Wildtype Mice
  710. Structure-functional characterization of cytochrome P4502E1 (CYP2E1)
  711. Establishment of model with exogenous human CYP2E1 expression and inducement of substrates
  712. Chlorzoxazone as a Single Sample Probe of Hepatic CYP2E1 Activity
  713. A relationship between genetic polymorphisms of CYP2E1 and susceptibility of acute leukemia in Gansu population
  714. Application of a map Bayesian method for CYP2E1 phenotyping
  715. Role of CYP2E1 Immunoglobulin G4
  716. Individual variability of CYP2E1 xenobiotic oxidation in human liver
  717. The genotype of CYP2E1 and liver-derived serum enzymes
  718. A-71G> T Nucleotide Substitution uncouples IFN-[gamma]-dependent Suppression of CYP2E1 mRNA
  719. Pathogenesis of nonalcoholic steatohohepatitis [sic]: the role of CYP2E1
  720. Hormonal regulation of CYP2E1 and CYP2C11 in rat liver and kidney
  721. Inhibition of Ethanol-induced CYP2E1 by Curcuma longa L. Extract
  722. Immunological detection of CYP2E1 in the fresh lymphocytes
  723. THE EFFECT OF COPROPHAGY ON THE EXPRESSION OF HEPATIC CYP2E1 DURING STARVATION
  724. Effects of Danshen and Its Active Components on Rat CYP2E1 Expression and Metabolism of Model CYP2E1 Probe Substrate
  725. Construction of CYP2E1 recombinant adenovirus vector and its anti-tumor effects
  726. CYP2E1-DEPENDENT BIOACTIVATION OF 191
  727. Role Of Cytochrome P450 2E1 (CYP2E1) In Trichloroethylene (TCE) Metabolism And Disposition: Comparative Studies Using CYP2E1-/-And Wild-Type Mice
  728. The role of CYP2E1 and CYP4A in the development of non-alcoholic steatohepatitis
  729. CYP2E1 VNTR polymorphisms and hepatocarcinoma: a gender-specific correlation
  730. Substrate inhibition of CYP2E1 activity is primarily determined by lipophilicity
  731. Expression of CYP2E1 gene in liver tissue in patients with hepatic cirrhosis and obstuctive jaundice
  732. Study on the association between CYP2E1 enzymes and susceptibility of alcoholic liver disease
  733. An investigation of the induction of hepatic CYP2E1 by low doses of nicotine in the rat.
  734. The Effects of CYP2E1 and CYP2C19 Polymorphisms on the Susceptibility for Gastric Cancer
  735. Time-coursed Changes of CYP2E1 Protein in Acute Liver Injury by a Single CCI₄ Administration in SD Rats
  736. Search for possible changes in murine gene CYP2E1 structural region under exposure to ionizing radiation
  737. MAPPING CONFORMATIONAL CYP2E1 EPITOPES RECOGNISED BY AUTO-ANTIBODIES IN HALOTHANE HEPATITIS AND ALCOHOLIC LIVER DISEASE
  738. The Genetic Polymorphism of CYP2E1 in a Korean Healthy Subjects and Hepatocellular Carcinoma Patients
  739. Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratio
  740. CYP2E1 Genetic Polymorphism relating to Styrene Metabolism of Korean Workers
  741. Pharmacokinetics of drug interactions due to ligand stabilization of CYP2E1
  742. Determination of the activity of human hepatic cytochromes P450 CYP2C8/9, CYP2E1
  743. ALLELIC VARIANTS OF CYP2E1 GENE IN HEPATOCARCINOMA PATIENTS AND IN HEPATIC TUMOR CELL LINES
  744. e0048 CYP2E1 increases oxidative stress and induces apoptosis of cardio myocytes in transgenic mice
  745. Catalytic activity and quantitation of CYP2E1 in human embryonic and fetal brain tissues
  746. Various Fatty Acids Induce Cell Damages Differently in CYP2E1-transduced HepG2 Cells, E47 Cells, Compared to C34 Cells
  747. Polymorphisms of ADH2, ALDH2 and CYP2E1 in huichol and Mestizo subjects from western México in comparison with other populations of the world
  748. Cloning and sequence analysis of human embryonic nasopharyngeal epithelial CYP2E1 cDNA
  749. The influence of Jiuganning decoction on the content of CYP2E1 and cytokine IL-6, TNF in rats models of alcoholic hepatic injury
  750. Identification of a critical CYP2E1 epitope in patients with drug-induced liver injury from anesthetics (93.16)
  751. Experimental study on effect of Erchen decoction and Taohongsiwu decoction on CYP2E1 activities in non-alcoholic fatty liver rats
  752. Use of Cytochrome P450 2E1 (CYP2E1) Knockout Transgenic Mouse Model to Study the Role of CYP2E1 in Carbon Tetrachloride-and Alcohol-mediated …
  753. The role of CYP2A6 and CYP2E1 in the metabolism of 3-methylindole in porcine hepatocytes.
  754. Role of CYP2E1 in Impaired Nitric Oxide Synthase (NOS)‐Dependent Cerebral Vasodilation During Chronic Alcohol Consumption
  755. Increased citrate levels in non-alcoholic steatohepatitis: effect on CYP2E1
  756. The Role of CYP2E1 IgG4 Subclass Autoantibodies in the Development of Anesthetic Sensitization
  757. Cutaneous CYP2E1 induction after topical treatment by dexamethasone, ethanol and salicylic acid in mouse.
  758. Meta-analysis on relationship between polymorphisms of CYP2E1 gene and susceptibility to antituberculosis drug-induced liver injury
  759. Modulation of Murine CYP2E1 Activity by Disulfiram on Trichloroethylene-Induced Neurotoxicity A Pilot Study
  760. Chlormethiazole, an inhibitor of CYP2E1, prevented chemical carcinogen-initiated and alcohol-promoted hepatic carcinongenesis in rats.
  761. Single Nucleotide Polymorphisms in the Non-coding region of CYP2E1 among Koreans
  762. The Effects of Poly IC and Human Interferon ɑ on Rat Hepatic Cyp4a1 and CYP2E1
  763. Inhibition of Urethane-Induced Carcinogenicity in CYP2E1-/-Vs. CYP2E1+/+ Mice
  764. Polymorphism of CYP2E1 gene and the risk of lung cancer among African-Americans and Caucasians in Los Angeles County (California).
  765. Association of the blood biochemical index with CYP2E1 5’flanking region Rsa I/Pst I gene polymorphism and alcohol consumption habit in Southern Taiwan …
  766. The Effects of Chungganhaeju-tang(Qingganjiejiu-tang) on Alcohol induced Cytotoxicity in CYP2E1-transfected HepG2 cells.
  767. Investigation of indazole unbinding pathways in CYP2E1 by molecular dynamics simulations
  768. CYP2E1: Mechanism of induction by isoniazid and role in acetaminophen oxidation
  769. The relationship between the GST T1, GST M1, CYP2E1 genotype and abnormal liver function in PVC workers
  770. Analyses of Mutation Frequency on the CYP2E1, ADH2, and ALDH2 Genes among Five Ethnic Groups
  771. Molecular Regulation of Ethanol-inducible P450 (CYP2E1) in Acute CCI₄Treatment
  772. CYP2E1-dependent bioactivation of 1, 1-dichloroethylene to reactive intermediates in murine and human lung and liver microsomes.
  773. CYP2E1 Mediates Ethanol-Induced DNA Damage And TNF Release In Bronchial Epithelial Cells
  774. Oral clefts, maternal exposure to solvents and CYP2E1 polymorphism
  775. Effect of γ-irradiation and mitomycin C (MMC) on CYP2B1 and CYP2E1 activities in rat hepatic microsomes in vitro
  776. The Effects of CYP2E1 on Hepatic Gene Expression in 129/Sv-CYP2E1^ tm1Gonz/J and 129S1/SvImJ Mice Exposed to Hydrazine
  777. Variable Number of Tandem Repeats (VNTR) gene polymorphism of CYP2E1 in patients with pancreatic adenocarcinoma
  778. THE EFFECT OF ETHANOL ON COUMARIN METABOLISM AND CYTOTOXICITY IN TRANSFECTED CULTURES OF HEPG2 CELLS WITH CYP2E1 EXPRESSION.
  779. Cytochrome P450 2E1 (CYP2E1) Induction By Pyridazine Produces Qualitative And Quantitative Changes In The Metabolism Of Trichloroethylene To Potentially …
  780. Inhibition of B12‐dependent methionine synthase activity in HepG2 cells over‐expressing CYP2E1
  781. Overexpression of CYP2E1 Increases Sensitivity of HepG2 Cells to Isoniazid-Induced Cytotoxicity
  782. Relation between genetic polymorphisms of ADH, CYP2E1, GSTP1 and their expression in Caucasian lung tissue
  783. Detection of autoantibodies against cytochrome P450 2E1 (CYP2E1) in patients with recurrent hepatitis C
  784. Association of GSTM1, P1, T1 and CYP2E1 Single Nucleotide Polymorphisms with Colorectal Cancer in Iran: 391
  785. Lack of correlation between lymphocytic mrna expression and activity of CYP3A4 and CYP2E1 In‐vivo in alcoholics and non‐alcoholics
  786. RELATIONSHIPS BETWEEN GENETIC POLYMORPHISMS IN CYP2D6 AND CYP2E1 GENES AND LIVER MICROSOMAL DRUG OXIDATION ACTIVITIES
  787. NADPH: CYTOCHROME P450 REDUCTASES OF VARIOUS SPECIES CAN BE USED IN SYSTEMS RECONSTITUTING DRUG-METABOLIZING CYP2E1 …
  788. Single nucleotide polymorphisms and variable number of tandem repeat polymorphism of CYP2E1 in Koreans
  789. Strain-related Differences in CYP2E1 Levels are Associated with Differential Bioactivation of 1, 1-dichloroethylene in Murine Lung and Liver
  790. Inductive Effect Of Pyridazine (Pz) On Cytochrome P4502E1 (CYP2E1) Alters The Metabolism Of Trichloroethylene (TCE)
  791. Interactive effects between genetic polymorphisms of CYP2E1 & NAT1 and smoking on the development of lung cancer in Korean
  792. RELATIONSHIPS BETWEEN GENETIC POLYMORPHISMS IN CYP2D6 AND CYP2E1 GENES AND LIVER MICROSOMAL DRUG OXIDATION ACTIVITIES-STUDIES …
  793. AhR Mediated Hematotoxicity Is Induced At The Site Of Bone Marrow Where Consequent CYP2E1-Derived Benzene Metabolites Locally Induce Their Toxicity
  794. The potent protective effect of red ginseng against acetaminophen-induced toxicity through metabolic regulation of CYP2E1 and GSTs
  795. CYP2E1 overexpression up-regulates both non-specific ô-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1
  796. Effects of CYP Inducers and Inhibitors on the Furosemide Pharmacokinetics: Involvement of CYP2E1 and 3A 1/2 for the Furosemide Metabolism
  797. Effect of tobacco smoke on the expression of Cyp1a, Cyp2b, Cyp2e, and Cyp3a subfamilies in mice. Possible role of CYP2E1 in pulmonary DNA single strand breaks …
  798. Proteomics of oxidative stress using inducible CYP2E1 expressing HEPG2 cells and 3T3-L1 adipocytes as model systems
  799. An estimate of polymorphism of ADH1B, ALDH2, and CYP2E1 alcohol biotransformation genes in Siberian indigenous and immigrant populations
  800. Effects of in vivo hepatic ischemia‐reperfusion injury on the CYP2E1‐mediated metabolism of chlorzoxazone and biliary clearance of its metabolite in isolated …
  801. Assessment of the role of cytochrome P450 2E1 (CYP2E1)-mediated metabolism in urethane-induced cell proliferation and gene expression: Biomarkers of …
  802. Effect of the South African traditional meat, biltong, on cancer-associated enzymes CYP2E1 and CYP1A2
  803. … of twelve chlorinated aliphatic hydrocarbons upon the cell cycle of Chinese hamster cell lines: V79d-MZ and genetically engineered cell lines expressing CYP2E1
  804. Association of the CYP2E1, FMO3, NQO1, GST, NOS3 genetic polymorphisms with ischemic stroke risk in Turkish population
  805. Alkyl sulfides Potentiation of Carbon Tetrachloride-induced Hepatotoxicity: The Role of CYP2E1 Expression
  806. The influence of alcohol on acetaminophen hepatotoxicity: CYP2E1 induction and selective mitochondrial glutathione depletion
  807. Interaction of genetic polymorphisms of glutathione S-transferase (GST) M1, GSTT1, and CYP2E1 in development of lung cancer
  808. A dietary ethanol protocol for CYP2E1 induction in CD-1 mice and its application to studies on the genotoxicity, immunotoxicity and metabolism of low-level benzene
  809. Genetic Polymorphism of CYP2E1, GSTT1/M1 and NQO1 on Biomarker of Urinary Spma Among Benzene-Exposed Workers
  810. A Composition of Metadoxine and Garlic Oil Abrogates Alcoholic Steatosis and CYP2E1 Induction in Rat Liver with AMPK Restoration
  811. The Association between Pneumoconiosis and Genetic Polymorphism of GSTM1, GSTT1, GSTP1, NAT2, CYP2E1 and CYP1A1
  812. The effect of trans-resveratrol analogues on the catalytic activities of CYP1A2 and CYP2E1 in mouse liver microsomes in vitro
  813. Genetic Polymorphisms of NAT2, CYP2C9, CYP2C19, CYP2D6 and CYP2E1, and Antituberculosis Drugs Induced Maculopapular Eruption
  814. Alterations in toxicokinetics of trichloroethylene (TCE) and trichloroacetic acid (TCA) due to cytochrome P450 2E1 (CYP2E1) induction
  815. The Role of Genetic Polymorphisms of CYP2E1, CYP1A1, NAT1, and NAT2 in Bladder Cancer in Korea
  816. Effects of benzene on liver, kidney and lung cyp1a, cyp2b4, CYP2E1 and cyp3a6 mrna, protein level, and drug metabolizing enzyme activities and toxicity in diabetic …
  817. Diphenyl-Dimethyl-Dicarboxylate Inhibits Carbon tetrachloride-induced Increase Kupffer Cell Counts in the Absence of CYP2E1 Suppression in the Rat
  818. Diallyl Sulfone, a Derivative of Garlic, Inactivates the Cytochrome P450 Enzyme CYP2E1 by Forming N-alkylprotoporphyrin Heme Adducts
  819. EFFECTS OF STRUCTURALLY AND FUNCTIONALLY DIVERSE GROUP OF PHYTOCHEMICALS ON ANILINE HYDROXYLATION (CYP2E1) OF CONTROL AND …
  820. … Cytochrome P450 Reductase-null Mice as an Animal Model to Study Electron Transfer Pathways in Cholesterol Synthesis and CYP2E1-mediated Drug Metabolism
  821. MATERNAL SMOKING, POLYMORPHISMS IN CYP1A1, CYP2E1, EPHX1, NAT2, NQO1, AND CHILDHOOD ACUTE LEUKEMIA
  822. Evaluation of influence of Andrographis paniculata on activities of CYP1A2, CYP3A4, CYP2E1 and CYP2C19 genotypes in chickens by multiple cytochrome P450 …
  823. Saponins Isolated from the Root of Platycodi Radix Abrogates Alcoholic Steatosis and CYP2E1 Induction in Rat Liver with Restoration of AMPK Activity
  824. Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP1B1, CYP2E1, GSTM1, GSTT1, and NAT2) and p53 gene point mutations …
  825. Identification of 2‐Piperidone as a Biomarker of CYP2E1 Activity through Metabolomic Phenotyping
  826. The effects of the ALDH2* 1/2, CYP2E1 c1/c2 and C/D genotypes on blood ethanol elimination and the human serotonin receptor (HTR2) gene Msp1 polymorphism in …
  827. Elimination rate of 6-hydroxychlorzoxazone in urine as a non-invasive evaluation of cytochrome CYP2E1 activity. Lack of relationship to smoking
  828. IL-4 promotes experimental drug-induced hepatitis by reducing immune responses to haptenated proteins and inhibiting regulatory responses to native CYP2E1 …
  829. Computational Docking Investigations of Oxidative Metabolism of 4-Nitroanisole with CYP2E1
  830. CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease
  831. The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system
  832. The Role of CYP2E1 in the Drug Metabolism or Bioactivation in the Brain
  833. Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis
  834. Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling
  835. New insight and potential therapy for NAFLD: CYP2E1 and flavonoids
  836. A systematic evaluation of microRNAs in regulating human hepatic CYP2E1
  837. Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells
  838. CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis
  839. Induction of CYP2E1 in non-alcoholic fatty liver diseases
  840. Molecular dynamics simulations of CYP2E1
  841. Morbidly obese patients exhibit increased CYP2E1-mediated oxidation of acetaminophen
  842. CCl4-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat
  843. Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness
  844. Higher CYP2E1 activity correlates with hepatocarcinogenesis induced by diethylnitrosamine
  845. CYP2E1 autoantibodies in liver diseases
  846. Role of CYP2E1 in mitochondrial dysfunction and hepatic injury by alcohol and non-alcoholic substances
  847. CYP2E1 in alcoholic and non-alcoholic liver injury. Roles of ROS, reactive intermediates and lipid overload
  848. Impairment of Akt activity by CYP2E1 mediated oxidative stress is involved in chronic ethanol-induced fatty liver
  849. Induction of brain CYP2E1 by chronic ethanol treatment and related oxidative stress in hippocampus, cerebellum, and brainstem
  850. Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway
  851. Ethanol‐induced oxidative stress via the CYP2E1 pathway disrupts adiponectin secretion from adipocytes
  852. Association of NAT2, GST and CYP2E1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity
  853. Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis
  854. Autophagy protects against CYP2E1/chronic ethanol-induced hepatotoxicity
  855. NF-κB-mediated regulation of rat CYP2E1 by two independent signaling pathways
  856. The effect of quercetin on the pharmacokinetics of chlorzoxazone, a CYP2E1 substrate, in healthy subjects
  857. Downregulation of CYP2E1 is associated with poor prognosis and tumor progression of gliomas
  858. Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction
  859. … psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1
  860. Nrf2 and antioxidant defense against CYP2E1 toxicity
  861. Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability
  862. MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity
  863. Plasma exosomes exacerbate alcohol-and acetaminophen-induced toxicity via CYP2E1 pathway
  864. Antioxidant and pro-oxidant mechanisms of (+) catechin in microsomal CYP2E1-dependent oxidative stress
  865. Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis …
  866. Chronic alcohol intake-induced oxidative stress and apoptosis: role of CYP2E1 and calpain-1 in alcoholic cardiomyopathy
  867. Mouse spermatocytes express CYP2E1 and respond to acrylamide exposure
  868. Toward a systems approach to cytochrome P450 ensemble: interactions of CYP2E1 with other P450 species and their impact on CYP1A2
  869. Period1 mediates rhythmic metabolism of toxins by interacting with CYP2E1
  870. Involvement of CYP2E1-ROS-CD36/DGAT2 axis in the pathogenesis of VPA-induced hepatic steatosis in vivo and in vitro
  871. Sulforaphane induces Nrf2 and protects against CYP2E1-dependent binge alcohol-induced liver steatosis
  872. Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study
  873. Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol
  874. CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid
  875. Protective effects of taraxasterol against ethanol-induced liver injury by regulating CYP2E1/Nrf2/HO-1 and NF-κB signaling pathways in mice
  876. Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and …
  877. CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment
  878. Protective effects of diallyl disulfide against acetaminophen-induced nephrotoxicity: a possible role of CYP2E1 and NF-κB
  879. Low doses of curcumin protect alcohol-induced liver damage by modulation of the alcohol metabolic pathway, CYP2E1 and AMPK
  880. Toxicological implications of mitochondrial localization of CYP2E1
  881. Alcoholic liver disease: from CYP2E1 to CYP2A5
  882. Investigation of indazole unbinding pathways in CYP2E1 by molecular dynamics simulations
  883. CYP2E1, GSTM1 and GSTT1 genetic polymorphisms and susceptibility to antituberculosis drug‐induced hepatotoxicity: a nested case–control study
  884. Sex steroid hormones regulate constitutive expression of CYP2E1 in female mouse liver
  885. Antioxidant Properties of Proanthocyanidins Attenuate Carbon Tetrachloride (CCl4)–Induced Steatosis and Liver Injury in Rats via CYP2E1 Regulation
  886. … effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress
  887. Antioxidant Peptides from Protein Hydrolysate of Microalgae Navicula incerta and their Protective Effects in Hepg2/CYP2E1 Cells Induced by Ethanol
  888. Genetic Polymorphisms of Genes Coding to Alcohol‐Metabolizing Enzymes in Western Mexicans: Association of CYP2E1*c2/CYP2E1*5B Allele with Cirrhosis and …
  889. Ethanol-induced oxidative stress is associated with EGF receptor phosphorylation in MCF-10A cells overexpressing CYP2E1
  890. Role and importance of polymorphisms with respect to DNA methylation for the expression of CYP2E1 enzyme
  891. Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates
  892. Potential pathogenetic link between angiomyofibroblastoma and superficial myofibroblastoma in the female lower genital tract based on a novel MTG1-CYP2E1 fusion
  893. CYP2E1 epigenetic regulation in chronic, low-level toluene exposure: Relationship with oxidative stress and smoking habit
  894. The association between CYP2E1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs: a meta-analysis
  895. Binge alcohol promotes hypoxic liver injury through a CYP2E1–HIF-1α-dependent apoptosis pathway in mice and humans
  896. Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPARα-mediated lipogenic gene …
  897. Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress …
  898. CYP2E1 metabolism of styrene involves allostery
  899. ROS generated by CYP450, especially CYP2E1, mediate mitochondrial dysfunction induced by tetrandrine in rat hepatocytes
  900. Sex‐dependent regulation of cytochrome P450 family members Cyp1a1, CYP2E1, and Cyp7b1 by methylation of DNA
  901. The WNT/β-catenin pathway is a transcriptional regulator of CYP2E1, CYP1A2, and aryl hydrocarbon receptor gene expression in primary human hepatocytes
  902. Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis
  903. Association of CYP2E1 gene polymorphisms with bladder cancer risk: A systematic review and meta-analysis
  904. CYP2E1 regulates the development of radiation-induced pulmonary fibrosis via ER stress-and ROS-dependent mechanisms
  905. CYP2E1*5B, CYP2E1*6, CYP2E1*7B, CYP2E1*2, and CYP2E1*3 Allele Frequencies in Iranian Populations
  906. Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression
  907. Investigating the CYP2E1 potential role in the mechanisms behind INH/LPS-induced hepatotoxicity
  908. Enantioselective metabolism of phenylpyrazole insecticides by rat liver microsomal CYP3A1, CYP2E1 and CYP2D2
  909. CYP2E1 changes the biological function of gastric cancer cells via the PI3K/Akt/mTOR signaling pathway
  910. CYP2E1 hydroxylation of aniline involves negative cooperativity
  911. Salidroside protects mice against CCl4-induced acute liver injury via down-regulating CYP2E1 expression and inhibiting NLRP3 inflammasome activation
  912. Refined CYP2E1∗ Template∗∗ system to decipher the ligand-interactions
  913. Functional PstI/RsaI Polymorphism in CYP2E1 Is Associated with the Development, Progression and Poor Outcome of Gastric Cancer
  914. CYP2E1 RsaI/PstI polymorphism and risk of anti-tuberculosis drug-induced liver injury: a meta-analysis
  915. Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences
  916. Effect of ammonium pyrrolidine dithiocarbamate (PDTC) on NF-κB activation and CYP2E1 content of rats with immunological liver injury
  917. Prilocaine-and lidocaine-induced methemoglobinemia is caused by human carboxylesterase-, CYP2E1-, and CYP3A4-mediated metabolic activation
  918. CYP2E1 sensitizes the liver to LPS-and TNF α-induced toxicity via elevated oxidative and nitrosative stress and activation of ASK-1 and JNK mitogen …
  919. Induction of SIRT1 by melatonin improves alcohol‐mediated oxidative liver injury by disrupting the CRBN‐YY1‐CYP2E1 signaling pathway
  920. Human CYP2A6, CYP2B6, and CYP2E1 atropselectively metabolize polychlorinated biphenyls to hydroxylated metabolites
  921. Why hepatic CYP2E1-elevation by itself is insufficient for inciting NAFLD/NASH: Inferences from two genetic knockout mouse models
  922. Amalgamation of in-silico, in-vitro and in-vivo approach to establish glabridin as a potential CYP2E1 inhibitor
  923. Roles of CYP2E1 in 1, 2‐dichloroethane‐induced liver damage in mice
  924. High CYP2E1 activity correlates with hepatofibrogenesis induced by nitrosamines
  925. Baicalin ameliorates liver injury induced by chronic plus binge ethanol feeding by modulating oxidative stress and inflammation via CYP2E1 and NRF2 in …
  926. Relevance of CYP2E1 to non-alcoholic fatty liver disease
  927. Higher sensitivity of female cells to ethanol: methylation of DNA lowers CYP2E1, generating more ROS
  928. Protective effects of protein hydrolysate from marine microalgae Navicula incerta on ethanol-induced toxicity in HepG2/CYP2E1 cells
  929. Single-nucleotide polymorphisms in cytochrome P450 2E1 (CYP2E1) 3′-untranslated region affect the regulation of CYP2E1 by miR-570
  930. CYP2E1 polymorphisms and nasopharyngeal carcinoma risk: a meta-analysis
  931. The importance of CYP2E1 in the pathogenesis of alcoholic liver disease and drug toxicity and the role of the proteasome
  932. Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in a Chinese Tibetan population
  933. Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice
  934. Polydatin protects rat liver against ethanol-induced injury: involvement of CYP2E1/ROS/Nrf2 and TLR4/NF-B p65 pathway
  935. CYP2E1 in the human retinal pigment epithelium: expression, activity, and induction by ethanol
  936. Relationship of anti-tuberculosis drug-induced liver injury and genetic polymorphisms in CYP2E1 and GST
  937. Effect of piperine on CYP2E1 enzyme activity of chlorzoxazone in healthy volunteers
  938. … final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: role of CYP2E1 and Keap1-Nrf2 …
  939. Genetic Variability in CYP2E1 and Catalase Gene Among Currently and Formerly Alcohol-Dependent Male Subjects
  940. CYP2E1 induction leads to oxidative stress and cytotoxicity in glutathione-depleted cerebellar granule neurons
  941. Subcellular localization of rat CYP2E1 impacts metabolic efficiency toward common substrates
  942. Contributing roles of CYP2E1 and other cytochrome P450 isoforms in alcohol-related tissue injury and carcinogenesis
  943. Stat4 rs7574865 polymorphism promotes the occurrence and progression of hepatocellular carcinoma via the Stat4/CYP2E1/FGL2 pathway
  944. Effects of acrylamide on oxidant/antioxidant parameters and CYP2E1 expression in rat pancreatic endocrine cells
  945. CYP2E1 polymorphisms and colorectal cancer risk: a HuGE systematic review and meta-analysis
  946. Alcohol-induced CYP2E1, mitochondrial dynamics and retrograde signaling in human hepatic 3D organoids
  947. CYP2E1 gene promoter polymorphism-1293G> C increases the risk of essential hypertension in men with alcohol abuse
  948. Polymorphisms in NEIL-2, APE-1, CYP2E1 and mdm2 genes are independent predictors of gastric cancer Risk in a Northern Jiangsu Population (China)
  949. Interactions of inhibitor molecules with the human CYP2E1 enzyme active site
  950. Resveratrol pretreatment affects CYP2E1 activity of chlorzoxazone in healthy human volunteers
  951. Role of CYP2E1-mediated metabolism in the acute and vestibular toxicities of nineteen nitriles in the mouse
  952. Induction of CYP2E1 in testes of isoniazid-treated rats as possible cause of testicular disorders
  953. Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro
  954. Danshen (Salvia miltiorrhiza) water extract inhibits paracetamol-induced toxicity in primary rat hepatocytes via reducing CYP2E1 activity and oxidative stress
  955. Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance
  956. … patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, CYP2E1, gstm1 and gstt1
  957. In vitro inhibition of human CYP2E1 and CYP3A by quercetin and myricetin in hepatic microsomes is not gender dependent
  958. Cytochrome P450 2E1 (CYP2E1) positively regulates lipid catabolism and induces browning in 3T3-L1 white adipocytes
  959. Selective time-and NADPH-dependent inhibition of human CYP2E1 by clomethiazole
  960. Expression and activities of hepatic cytochrome P450 (CYP1A, CYP2A and CYP2E1) in entire and castrated male pigs
  961. Quercetin suppressed CYP2E1-dependent ethanol hepatotoxicity via depleting heme pool and releasing CO
  962. CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis
  963. Effects of unprocessed versus vinegar-processed Schisandra chinensis on the activity and mRNA expression of CYP1A2, CYP2E1 and CYP3A4 enzymes in rats
  964. … in rats induced by aqueous extract of Polygoni Multiflori Radix, root of Polygonum multiflorum related to the activity inhibition of CYP1A2 or CYP2E1
  965. Association between the CYP2E1 polymorphisms and lung cancer risk: a meta-analysis
  966. Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes
  967. Polymorphisms in GSTM1, CYP1A1, CYP2E1, and CYP2D6 are associated with susceptibility and chemotherapy response in non-small-cell lung cancer patients
  968. Role of CYP2E1 polymorphisms in breast cancer: a systematic review and meta-analysis
  969. TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity
  970. Tetra primer ARMS PCR optimization to detect single nucleotide polymorphisms of the CYP2E1 gene
  971. The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation
  972. Genetic variants of ALDH2-rs671 and CYP2E1-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population
  973. Genetic polymorphisms of CYP2E1 and DNA repair genes HOGG1 and XRCC1: association with hepatitis B related advanced liver disease and cancer
  974. Cytochrome P450 CYP2E1 suppression ameliorates cerebral ischemia reperfusion injury
  975. Association of genetic polymorphisms of CYP2E1, NAT2, GST and SLCO1B1 with the risk of anti-tuberculosis drug-induced liver injury: a systematic review …
  976. Genetic polymorphisms of CYP2E1 and GSTM1 loci and susceptibility to anti-tuberculosis drug-induced hepatotoxicity
  977. Nicotinamide N-oxidation by CYP2E1 in human liver microsomes
  978. CYP1A1 and CYP2E1 genotypes and risk of esophageal squamous cell carcinoma in a high-incidence region, Kashmir
  979. Potent mutagenicity of some non-planar tri-and tetrachlorinated biphenyls in mammalian cells, human CYP2E1 being a major activating enzyme
  980. Chronic acrylamide exposure in male mice results in elevated DNA damage in the germline and heritable induction of CYP2E1 in the testes
  981. Shanxi aged vinegar prevents alcoholic liver injury by inhibiting CYP2E1 and NADPH oxidase activities
  982. Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 over-expressing VL-17A cells
  983. The possible mechanisms of CYP2E1 interactions with HSP90 and the influence of ethanol on them
  984. Genetic polymorphisms of CYP2E1, GST, and NAT2 enzymes are not associated with risk of breast cancer in a sample of Lebanese women
  985. Urinary biomarker of prenatal exposure to disinfection byproducts, maternal genetic polymorphisms in CYP2E1 and GSTZ1, and birth outcomes
  986. CYP2E1 phenotype in Mexican workers occupationally exposed to low levels of toluene
  987. Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4
  988. Genetic polymorphism of cytochrome P450 (CYP) 1A1, CYP1A2, and CYP2E1 genes modulate susceptibility to gastric cancer in patients with Helicobacter …
  989. Cooperative effects for CYP2E1 differ between styrene and its metabolites
  990. Polymorphisms of the CYP1A1 and CYP2E1 genes in head and neck squamous cell carcinoma risk
  991. Effectiveness of antioxidant treatments on cytochrome P450 2E1 (CYP2E1) activity after alcohol exposure in humans and in vitro models: A systematic review
  992. Alteration in the expression of cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the liver of mouse induced by microcystin-LR
  993. Exploration of inhibition potential of isoniazid and its metabolites towards CYP2E1 in human liver microsomes through LC-MS/MS analysis
  994. Application of an updated physiologically based pharmacokinetic model for chloroform to evaluate CYP2E1-mediated renal toxicity in rats and mice
  995. Genetic polymorphisms of drug‐metabolizing phase I enzymes CYP2E1, CYP2A6 and CYP3A5 in South Indian population
  996. HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma cells
  997. Associations between CYP1A1 and CYP2E1 polymorphisms and susceptibility to esophageal cancer in Chaoshan and Taihang areas of China
  998. Featured structure-activity relationships for some tri-and tetrachlorobiphenyls in human CYP2E1-activated mutagenicity—impact of the extent of ortho-chlorination
  999. Polymorphisms of NAT2, CYP2E1, GST, and HLA related to drug-induced liver injury in indonesian tuberculosis patients
  1000. CHIP−/−-mouse liver: adiponectin-AMPK-FOXO-activation overrides CYP2E1-elicited JNK1-activation, delaying onset of NASH: therapeutic implications
  1001. Protective effect of curcumin on acrylamide-induced hepatic and renal impairment in rats: Involvement of CYP2E1
  1002. Associations of CYP2E1 rs2031920 and rs3813867 polymorphisms with colorectal cancer risk: a systemic review and meta-analysis
  1003. Altered vulnerability to asthma at various levels of ambient Benzo [a] Pyrene by CTLA4, STAT4 and CYP2E1 polymorphisms
  1004. CYP2E1 Rsa I/Pst I polymorphism contributes to oral cancer susceptibility: a meta-analysis
  1005. Genetic polymorphisms of SLCO1B1, CYP2E1 and UGT1A1 and susceptibility to anti-tuberculosis drug-induced hepatotoxicity: a Chinese population-based …
  1006. CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population
  1007. Triptolide regulates oxidative stress and inflammation leading to hepatotoxicity via inducing CYP2E1
  1008. Resveratrol downregulates CYP2E1 and attenuates chemically induced hepatocarcinogenesis in SD rats
  1009. Development of an IgY antibody-based immunoassay for the screening of the CYP2E1 inhibitor/enhancer from herbal medicines
  1010. Inhibition of CYP2E1 leads to decreased malondialdehyde–acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure
  1011. Association between polymorphism of GSTP1, GSTT1, GSTM1 and CYP2E1 genes and susceptibility to benzene-induced hematotoxicity
  1012. … bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in …
  1013. Human placental lactogen induces CYP2E1 expression via PI 3-kinase pathway in female human hepatocytes
  1014. Regulation of X-Ray Irradiation on the Activity and Expression Levels of CYP1A2 and CYP2E1 in Rats
  1015. Nanoformulated SOD1 ameliorates the combined NASH and alcohol-associated liver disease partly via regulating CYP2E1 expression in adipose tissue and liver
  1016. The essential role of CYP2E1 in metabolism and hepatotoxicity of N, N-dimethylformamide using a novel CYP2E1 knockout mouse model and a population study
  1017. Genotoxicity of 1‐methylpyrene and 1‐hydroxymethylpyrene in chinese hamster V79‐derived cells expressing both human CYP2E1 and SULT1A1
  1018. Simultaneous phenotyping of CYP2E1 and CYP3A using oral chlorzoxazone and midazolam microdoses
  1019. Genetic Polymorphisms in CYP2E1: Association with Schizophrenia Susceptibility and Risperidone Response in the Chinese Han Population
  1020. Human CYP2E1-activated mutagenicity of dioxin-like PCBs 105 and 118—Experimental data consistent with molecular docking results
  1021. CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes
  1022. Aidi injection altered the activity of CYP2D4, CYP1A2, CYP2C19, CYP3A2, CYP2E1 and CYP2C11 in normal and diethylnitrosamine-induced hepatocellular …
  1023. Investigation of the inhibition of eight major human cytochrome P450 isozymes by a probe substrate cocktail in vitro with emphasis on CYP2E1
  1024. Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury
  1025. Inhibitory effects of cytochrome P450 enzymes CYP1A2, CYP2A6, CYP2E1 and CYP3A4 by extracts and alkaloids of Gelsemium elegans roots
  1026. Concentration-dependent inhibitory effect of baicalin on the plasma protein binding and metabolism of chlorzoxazone, a CYP2E1 probe substrate, in rats in …
  1027. The activity, protein, and mRNA expression of CYP2E1 and CYP3A1 in rats after exposure to acute and chronic high altitude hypoxia
  1028. Synergistic association of PTGS2 and CYP2E1 genetic polymorphisms with lung cancer risk in northeastern Chinese
  1029. Structural basis for cooperative binding of azoles to CYP2E1 as interpreted through guided molecular dynamics simulations
  1030. CYP2E1 plays a suppressive role in hepatocellular carcinoma by regulating Wnt/Dvl2/β-catenin signaling
  1031. Genetic interaction between NAT2, GSTM1, GSTT1, CYP2E1, and environmental factors is associated with adverse reactions to anti-tuberculosis drugs
  1032. Polymorphisms of drug-metabolizing enzyme CYP2E1 in Chinese Uygur population
  1033. Organosulfur compounds in fermented garlic extracts and the effects on alcohol induced cytotoxicity in CYP2E1-transfected HepG2 cells
  1034. TA allele of rs2070673 in the CYP2E1 gene is associated with lobular inflammation and nonalcoholic steatohepatitis in patients with biopsy‐proven nonalcoholic fatty …
  1035. Metallothionein protects against isoniazid-induced liver injury through the inhibition of CYP2E1-dependent oxidative and nitrosative impairment in mice
  1036. The impact of psychogenic stressors on oxidative stress markers and patterns of CYP2E1 expression in mice liver
  1037. A single nucleotide polymorphism in the CYP2E1 gene promoter affects skatole content in backfat of boars of two commercial Duroc-sired crossbred populations
  1038. Salvia fruticosa Modulates mRNA Expressions and Activity Levels of Xenobiotic Metabolizing CYP1A2, CYP2E1, NQO1, GPx, and GST Enzymes in Human …
  1039. Ethanol self-administration and nicotine treatment induce brain levels of CYP2B6 and CYP2E1 in African green monkeys
  1040. Inhibition of CYP2E1 attenuates myocardial dysfunction in a murine model of insulin resistance through NLRP3-mediated regulation of mitophagy
  1041. CYP2E1 RsaI/PstI polymorphism and gastric cancer susceptibility: meta-analyses based on 24 case-control studies
  1042. CYP2E1-catalyzed alcohol metabolism: Role of oxidant generation in interferon signaling, antigen presentation and autophagy
  1043. Role of exposure/recovery schedule in micronuclei induction by several promutagens in V79-derived cells expressing human CYP2E1 and SULT1A1
  1044. Protective effect of Schisandra chinensis total lignans on acute alcoholic-induced liver injury related to inhibiting CYP2E1 activation and activating the Nrf2/ARE …
  1045. Effect of Acrylamide Treatment on CYP2E1 Expression and Redox Status in Rat Hepatocytes
  1046. Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma
  1047. … Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe …
  1048. Association of CYP2E1, STK15 and XRCC1 polymorphisms with risk of breast cancer in Malaysian women
  1049. Alcohol suppresses cardiovascular diurnal variations in male normotensive rats: Role of reduced PER2 expression and CYP2E1 hyperactivity in the heart
  1050. Reduced systemic toxicity and preserved vestibular toxicity following co-treatment with nitriles and CYP2E1 inhibitors: a mouse model for hair cell loss
  1051. CYP2E1 impairs GLUT4 gene expression and function: NRF2 as a possible mediator
  1052. Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures
  1053. Relationship of NAT2, CYP2E1 and GSTM1/GSTT1 polymorphisms with mild elevation of liver enzymes in Brazilian individuals under anti-tuberculosis drug …
  1054. CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms
  1055. The impact of CYP1A2 and CYP2E1 genes polymorphism on theophylline response
  1056. Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1
  1057. The modifying effect of CYP2E1, GST, and mEH genotypes on the formation of hemoglobin adducts of acrylamide and glycidamide in workers exposed to acrylamide
  1058. Adverse outcome pathway on CYP2E1 activation leading to liver cancer
  1059. Increased DNA damage is not associated to polymorphisms in OGGI DNA repair gene, CYP2E1 detoxification gene, and biochemical and hematological findings in …
  1060. CYP2E1 and miRNA‐378a‐3p contribute to acetaminophen‐or tripterygium glycosides‐induced hepatotoxicity
  1061. Dietary aflatoxin B1 intake, genetic polymorphisms of CYP1A2, CYP2E1, EPHX1, GSTM1, and GSTT1, and gastric cancer risk in Korean
  1062. Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes
  1063. Allyl methyl trisulfide protected against acetaminophen (paracetamol)-induced hepatotoxicity by suppressing CYP2E1 and activating Nrf2 in mouse liver
  1064. Glabridin attenuates paracetamol-induced liver injury in mice via CYP2E1-mediated inhibition of oxidative stress
  1065. A regulatory variant in CYP2E1 affects the risk of lung squamous cell carcinoma
  1066. Insulin resistance enhances binge ethanol-induced liver injury through promoting oxidative stress and up-regulation CYP2E1
  1067. Association between CYP2E1 polymorphisms and risk of gastric cancer: An updated meta‑analysis of 32 case‑control studies
  1068. CYP2E1 gene polymorphisms related to the formation of coronary artery lesions in Kawasaki disease
  1069. Insights into insulin-mediated regulation of CYP2E1: miR-132/-212 targeting of CYP2E1 and role of phosphatidylinositol 3-kinase, Akt (protein kinase B), mammalian …
  1070. CYP1AI and CYP2E1 gene polymorphisms may increase susceptibility to Oral Submucous Fibrosis among betel quid chewers of Eastern India
  1071. Extract of Jasminum grandiflorum L. alleviates CCl4-induced liver injury by decreasing inflammation, oxidative stress and hepatic CYP2E1 expression in mice
  1072. Effect of CYP2E1 gene polymorphisms on lamb odor and flavor in Indonesian sheep
  1073. Coordinate regulation of CYP2E1 by β-catenin-and hepatocyte nuclear factor 1α-dependent signaling
  1074. Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription
  1075. Association between polymorphisms in the CYP1A1, CYP2E1 and GSTM1 genes, and smoking, alcohol and upper digestive tract carcinomas in a high …
  1076. Intracellular ethanol‐mediated oxidation and apoptosis in HepG2/CYP2E1 cells impaired by two active peptides from seahorse (Hippocampus kuda bleeler) protein …
  1077. The genetic profiles of CYP1A1, CYP1A2 and CYP2E1 enzymes as susceptibility factor in xenobiotic toxicity in Turkish population
  1078. CYP2E1 PstI/RsaI polymorphism and interaction with alcohol consumption in hepatocellular carcinoma susceptibility: evidence from 1,661 cases and 2,317 controls
  1079. A novel role of CYP2E1 in human megakaryocyte development
  1080. Inhibition of CYP2E1 and activation of Nrf2 signaling pathways by a fraction from Entada africana alleviate carbon tetrachloride-induced hepatotoxicity
  1081. Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia
  1082. The LRP6 functional mutation rs2302685 contributes to individual susceptibility to alcoholic liver injury related to the Wnt/β-catenin-TCF1-CYP2E1 signaling pathway
  1083. Hepatoprotective Effect of Loquat Leaf Flavonoids in PM2.5-Induced Non-Alcoholic Fatty Liver Disease via Regulation of IRs-1/Akt and CYP2E1/JNK Pathways
  1084. … ‐en‐Y gastric bypass surgery influenced pharmacokinetics of several drugs given as a cocktail with the highest impact observed for CYP1A2, CYP2C8 and CYP2E1 …
  1085. Alcohol intake and folate antagonism via CYP2E1 and ALDH1: Effects on oral carcinogenesis
  1086. High CYP2E1 activity aggravates hepatofibrosis by limiting macrophage polarization towards the M2 phenotype
  1087. … of interactions of cathinone with human recombinant cytochrome P450 CYP (1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5
  1088. Upregulation of CYP2E1 expression causes oxidative damage induced by 2-chloroethanol in primary cultured rat astrocytes
  1089. Relationships among N, N-dimethylformamide exposure, CYP2E1 and TM6SF2 genes, and non-alcoholic fatty liver disease
  1090. Epididymal CYP2E1 plays a critical role in acrylamide-induced DNA damage in spermatozoa and paternally mediated embryonic resorptions
  1091. CYP2E1, oxidative stress and MAPK signaling pathways in alcohol-induced hepatotoxicity
  1092. Romidepsin (FK228) in a mouse model of lipopolysaccharide-induced acute kidney injury is associated with down-regulation of the CYP2E1 gene
  1093. Effects of insulin treatment on hepatic CYP1A1 and CYP2E1 activities and lipid peroxidation levels in streptozotocin-induced diabetic rats
  1094. The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2-and Akt-dependent mechanism
  1095. CYP17A1 and CYP2E1 variants associated with high altitude polycythemia in Tibetans at the Qinghai-Tibetan Plateau
  1096. Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3
  1097. … of 95% khat ethanol extract (KEE) on human recombinant cytochrome P450 (CYP) 1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2 and CYP3A5
  1098. Genetic polymorphism of the drug-metabolizing enzyme Cytochrome P4502E1 (CYP2E1) in a healthy Saudi population
  1099. Oxidative stress caused by a SOD1 deficiency ameliorates thioacetamide-triggered cell death via CYP2E1 inhibition but stimulates liver steatosis
  1100. Synonymous mutation rs2515641 affects CYP2E1 mRNA and protein expression and susceptibility to drug-induced liver injury
  1101. Increased Expression of CYP2E1 gene in gastric cancer may be a molecular marker for mazandaran province population
  1102. Relative contributions of CYP1A2 and CYP2E1 to the bioactivation and clearance of 4-aminobiphenyl in adult mice
  1103. CYP2E1, oxidative stress, post-translational modifications and lipid metabolism
  1104. CYP2E1 RsaI and 96-bp insertion genetic polymorphisms associated with risk for colorectal cancer
  1105. … stem cells rescue rat hippocampal cells from aluminum oxide nanoparticle-induced apoptosis via regulation of P53, Aβ, SOX2, OCT4, and CYP2E1
  1106. High-Risk HPV with Multiple Infections Promotes CYP2E1, Lipoperoxidation and Pro-Inflammatory Cytokines in Semen of Asymptomatic Infertile Men
  1107. Covalent modification and time-dependent inhibition of human CYP2E1 by the meta-isomer of acetaminophen
  1108. Impact of CYP2E1, GSTA1 and GSTP1 gene variants on serum alpha glutathione S-transferase level in patients undergoing anaesthesia
  1109. Effects of Flavonoids in Lysimachia clethroides Duby on the Activities of Cytochrome P450 CYP2E1 and CYP3A4 in Rat Liver Microsomes
  1110. Involvement of CYP2E1 in the course of brain edema induced by subacute poisoning with 1, 2-Dichloroethane in mice
  1111. Garlic oil alleviated ethanol-induced fat accumulation via modulation of SREBP-1, PPAR-α, and CYP2E1
  1112. DNA damage in peripheral blood lymphocytes and association with polymorphisms in the promoter region of the CYP2E1 gene in alcoholics from Central Brazil
  1113. CYP2E1 RsaI/PstI polymorphism and liver cancer risk among east Asians: a HuGE review and meta-analysis
  1114. Inhibition of CYP2E1 With Propylene Glycol Does Not Protect Against Hepatocellular Injury in Human Acetaminophen Daily‐Dosing Model
  1115. Ferric citrate CYP2E1-independently promotes alcohol-induced apoptosis in HepG2 cells via oxidative/nitrative stress which is attenuated by pretreatment with …
  1116. Functional PstI/RsaI polymorphisms in the CYP2E1 gene among south Indian populations
  1117. Interactions between CYP2E1 and CYP2B4: effects on affinity for NADPH-cytochrome P450 reductase and substrate metabolism
  1118. … quantification of metabolic reaction products catalysed by CYP2E1 enzyme activity: inhibitory effect of cytochrome P450 enzyme CYP2E1 by salicylic acid in rat liver …
  1119. Genetic variation of ABCB1 (rs1128503, rs1045642) and CYP2E1 rs3813867 with the duration of tuberculosis therapy: a pilot study among tuberculosis …
  1120. Lrp6 Genotype affects Individual Susceptibility to Nonalcoholic Fatty Liver Disease and Silibinin Therapeutic Response via Wnt/β-catenin-CYP2E1 Signaling
  1121. RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure
  1122. The polymorphism rs2480258 within CYP2E1 is associated with different rates of acrylamide metabolism in vivo in humans
  1123. Quercetin prevents type 1 diabetic liver damage through inhibition of CYP2E1
  1124. Protective effect of Ornithogalum saundersiae Ait (Liliaceae) against acetaminophen-induced acute liver injury via CYP2E1 and HIF-1α
  1125. Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism
  1126. RsaI but not DraI polymorphism in CYP2E1 gene increases the risk of gastrointestinal cancer in Malaysians: a case–control study
  1127. Interactions between CYP2E1, GSTZ1 and GSTT1 polymorphisms and exposure to drinking water trihalomethanes and their association with semen quality
  1128. Epilobium hirsutum alters xenobiotic metabolizing CYP1A1, CYP2E1, NQO1 and GPx activities, mRNA and protein levels in rats
  1129. Association of GSTM1, GSTT1, GSTP1 and CYP2E1 single nucleotide polymorphisms with colorectal cancer in Iran
  1130. Human CYP2E1-dependent mutagenicity of mono-and dichlorobiphenyls in Chinese hamster (V79)-derived cells
  1131. The Inhibition Effect of the Seaweed Polyphenol, 7-Phloro-Eckol from Ecklonia Cava on Alcohol-Induced Oxidative Stress in HepG2/CYP2E1 Cells
  1132. CYP2E1 testis expression and alcohol-mediated changes of rat spermatogenesis indices and type I collagen
  1133. π–π Stacking mediated drug–drug interactions in human CYP2E1
  1134. Modulation of mRNA expression and activities of xenobiotic metabolizing enzymes, CYP1A1, CYP1A2, CYP2E1, GPx and GSTP1 by the Salicornia freitagii extract in …
  1135. Pretreatment with turmeric modulates the inhibitory influence of cisplatin and paclitaxel on CYP2E1 and CYP3A1/2 in isolated rat hepatic microsomes
  1136. Characterization of polymorphisms of genes ADH2, ADH3, ALDH2 and CYP2E1 and relationship to the alcoholism in a Colombian population
  1137. Correlation between spermatogenesis disorders and rat testes CYP2E1 mRNA contents under experimental alcoholism or type I diabetes
  1138. Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats
  1139. CYP2E1 polymorphism, acetylator profiles and drug-induced liver injury incidence of Indonesian tuberculosis patients
  1140. Aspartame administration and insulin treatment altered brain levels of CYP2E1 and CYP3A2 in streptozotocin-induced diabetic rats
  1141. Increased oxidative stress and toxicity in ADH and CYP2E1 overexpressing human hepatoma VL-17A cells exposed to high glucose
  1142. Targeted delivery of CYP2E1 recombinant adenovirus to malignant melanoma by bone marrow-derived mesenchymal stem cells as vehicles
  1143. Effects of ethanol on CYP2E1 levels and related oxidative stress using a standard balanced diet
  1144. Genotype-Environment Interaction Analysis of NQO1, CYP2E1, and NAT2 Polymorphisms and the Risk of Childhood Acute Lymphoblastic Leukemia: A …
  1145. Polymorphisms in CYP2E1, GSTM1 and GSTT1 and anti-tuberculosis drug-induced hepatotoxicity
  1146. Effect of eurycomanone on cytochrome P450 isoforms CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2E1 and CYP3A4 in vitro
  1147. CYP2E1 genetic polymorphism with dietary, tobacco, alcohol habits, H. pylori infection status and susceptibility to stomach cancer in Mizoram, India
  1148. Caralluma umbellata Haw. protects liver against paracetamol toxicity and inhibits CYP2E1
  1149. CYP2E1 rs2031920, COMT rs4680 polymorphisms, cigarette smoking, alcohol use and lung cancer risk in a Japanese population
  1150. Genetic variations in the drug metabolizing enzyme, CYP2E1, among various ethnic populations of Pakistan
  1151. Persimmon vinegar and its fractions protect against alcohol-induced hepatic injury in rats through the suppression of CYP2E1 expression
  1152. … experimental and theoretical study of ROS scavenging by organosulfur compounds from garlic: In silico analysis of metabolic pathways and interactions on CYP2E1
  1153. Cytochrome P450 genes (CYP2E1 and CYP1A1) variants and susceptibility to chronic hepatitis B virus infection
  1154. Does CYP2E1 RsaI/PstI polymorphism confer head and neck carcinoma susceptibility?: A meta-analysis based on 43 studies
  1155. … -2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2
  1156. Association of mitochondrial deoxyribonucleic acid mutation with polymorphism in CYP2E1 gene in oral carcinogenesis
  1157. Liver cancer-related gene CYP2E1 expression in HBV transgenic mice with acute liver injury
  1158. Evolution of camel CYP2E1 and its associated power of binding toxic industrial chemicals and drugs
  1159. Mannan‐binding lectin attenuates acetaminophen‐induced hepatotoxicity by regulating CYP2E1 expression via ROS‐dependent JNK/SP1 pathway
  1160. Frequency distribution of high risk alleles of CYP2C19, CYP2E1, CYP3A4 genes in Haryana population
  1161. CYP2E1 T7632A and 9-bp insertion polymorphisms and colorectal cancer risk: a meta-analysis based on 4,592 cases and 5,918 controls
  1162. Comparing the protective effects of three sulfur compounds against acrylonitrile-induced acute toxicity in CYP2E1-induced rats
  1163. CYP2C8 and CYP2E1 genetic variants increase risk of tuberculosis in northwest Chinese Han population
  1164. Polymorphisms in the CYP2E1 and GSTM1 Genes as Possible Protection Factors for Leprosy Patients
  1165. Mutagenic Activity of N‐Nitrosodiethylamine in Cell Lines Expressing Human CYP2E1—Adequacy of Dimethylsulfoxide as Solvent
  1166. Identification of 2-piperidone as a biomarker of CYP2E1 activity through metabolomic phenotyping
  1167. A Systematically Combined Genotype and Functional Combination Analysis of CYP2E1, CYP2D6, CYP2C9, CYP2C19 in Different Geographic Areas of …
  1168. Association between genetic variants in CYP2E1 and CTRC genes and susceptibility to alcoholic pancreatitis: A systematic review and meta-analysis
  1169. Direct sequencing and comprehensive screening of genetic polymorphisms on CYP2 family genes (CYP2A6, CYP2B6, CYP2C8, and CYP2E1) in five ethnic …
  1170. Changes in coumarin kinetics and subcellular localization of CYP2E1 contribute to bile duct damage and reduce hepatocellular damage after repeated administration …
  1171. Ultrasensitive quantification of the CYP2E1 probe chlorzoxazone and its main metabolite 6-hydroxychlorzoxazone in human plasma using ultra performance liquid …
  1172. Human CYP2E1-dependent and human sulfotransferase 1A1-modulated induction of micronuclei by benzene and its hydroxylated metabolites in Chinese hamster …
  1173. Age-dependent features of CYP3A, CYP2C, and CYP2E1 functioning at metabolic syndrome
  1174. Association of CYP2E1 and NAT2 polymorphisms with lung cancer susceptibility among Mongolian and Han populations in the Inner Mongolian region
  1175. Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors
  1176. In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV …
  1177. N-Hydroxylation of 4-Aminobiphenyl by CYP2E1 Produces Oxidative Stress in a Mouse Model of Chemically Induced Liver Cancer
  1178. Investigation of CYP2E1 and Caspase-3 Gene Expressions in COVID-19 patients
  1179. How mutations affecting the ligand-receptor interactions: a combined MD and QM/MM calculation on CYP2E1 and its two mutants
  1180. Over-expression of CYP2E1 mRNA and protein: implications of xenobiotic induced damage in patients with de novo acute myeloid leukemia with inv (16)(p13. 1q22); …
  1181. CYP2E1 and GSTM1 gene polymorphisms, environmental factors, and the susceptibility to lung cancer
  1182. Susceptibility to the acute toxicity of acrylonitrile in streptozotocin-induced diabetic rats: protective effect of phenethyl isothiocyanate, a phytochemical CYP2E1 …
  1183. Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and CYP2E1 expression levels
  1184. 4-Fluoromethamphetamine (4-FMA) induces in vitro hepatotoxicity mediated by CYP2E1, CYP2D6, and CYP3A4 metabolism
  1185. In-Vitro CYP3A4, CYP2E1 and UGT activity in human liver microsomes by Strobilanthes crispus leaf extracts
  1186. Red meat intake, CYP2E1 and PPARγ polymorphisms, and colorectal cancer risk
  1187. The effects of non-esterified fatty acids and β-hydroxybutyrate on the hepatic CYP2E1 in cows with clinical ketosis
  1188. Association of GSTM1, GSTT1 and CYP2E1 gene polymorphisms with antituberculosis drug induced hepatotoxicity in North Indian population
  1189. Contributions of caspase-8 and-9 to liver injury from CYP2E1-produced metabolites of halogenated hydrocarbons
  1190. Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells overexpressing CYP2E1
  1191. Crosstalk between CYP2E1 and PPARα substrates and agonists modulate adipose browning and obesity
  1192. CYP2E1 inhibition and NF_κB Signaling Pathway are Involved in the Protective Molecular Effect of Origanum floribundum against Acetaminophen-induced …
  1193. The polymorphism of CYP2E1 Rsa I/Pst I gene and susceptibility to respiratory system cancer: a systematic review and meta-analysis of 34 studies
  1194. Association analysis of SNPs in the porcine CYP2E1 gene with skatole, indole, and androstenone levels in backfat of a crossbred pig population
  1195. Fermented Curcuma longa L. Prevents Alcoholic Fatty Liver Disease in Mice by Regulating CYP2E1, SREBP-1c, and PPAR-α
  1196. Structure-toxicity relationship study of para-halogenated styrene analogues in CYP2E1 transgenic cells
  1197. 1, 3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice
  1198. CYP2E1 gene rs6413420 polymorphism was first found in the Bouyei ethnic group of China
  1199. Chemical characteristics for optimizing CYP2E1 inhibition
  1200. Hepatoprotective effect of 10% ethanolic extract from Curdrania tricuspidata leaves against ethanol-induced oxidative stress through suppression of CYP2E1
  1201. Association between CYP2E1 and GOT2 gene polymorphisms and susceptibility and low-dose N, N-dimethylformamide occupational exposure-induced liver injury
  1202. A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma
  1203. Novel CYP2E1 haplotype identified in a South African cohort
  1204. Adrenergic blocker terazosin potentially suppresses acetaminophen induced-acute liver injury in animal models via CYP2E1 gene
  1205. Human CYP2E1‐dependent mutagenicity of benzene and its hydroxylated metabolites in V79‐derived cells: Suppression and enhancement by ethanol pretreatment
  1206. Vitamin E in vivo studies on the activity of antioxidant enzymes and CYP2E1 expression in high PUFA-treated brains
  1207. Identification of cytochrome CYP2E1 as critical mediator of alcohol effects on steatotic hepatocytes
  1208. A study on the optimization of CYP2E1 enzyme activity in C57Bl/6 mouse brain and liver
  1209. Chemoprotective Effect of Daphnetin Against Benzene-induced Leukemia via Alteration of CYP2E1
  1210. Contribution of CYP2E1 polymorphism to aging in the mechanical workshop workers
  1211. Ethanol-induced oxidative stress modifies inflammation and angiogenesis biomarkers in retinal pigment epithelial cells (ARPE-19): role of CYP2E1 and its inhibition …
  1212. The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65
  1213. … effect of seed coat ofEuryale ferox extract in non-alcoholic fatty liver disease induced by high-fat diet in mice by increasing IRs-1 and inhibiting CYP2E1
  1214. Kaempferol’s protective effect on ethanol-induced mouse primary hepatocytes injury involved in the synchronous inhibition of SP1, Hsp70 and CYP2E1
  1215. Targeted CYP2E1 quantification and its correlation to currently acceptable clinical biochemical indices
  1216. Research on the progress of alcoholic liver disease pathogenesis related to CYP2E1
  1217. Effect of jujube on the expression of CYP2E1 and TNF-alpha in the hepatic tissue of mice with alcoholic liver disease
  1218. Establishment of a p-nitrophenol oxidation-based assay for the analysis of CYP2E1 activity in intact hepatocytes in vitro
  1219. No association of CYP2E1 genetic polymorphisms with alcohol dependence in Han Taiwanese population
  1220. Roles of CYP1A1 and CYP2E1 gene polymorphisms in Oral submucous fibrosis
  1221. Significant genotype difference in the CYP2E1 PstI polymorphism of indigenous groups in Sabah, Malaysia with Asian and non-Asian populations
  1222. Camelus dromedarius putative cytochrome P450 enzyme CYP2E1: complete coding sequence and phylogenetic tree
  1223. Alteration of CYP2E1, DBN1, DNMT1, miRNA-335, miRNA-21, c-Fos and Cox-2 gene expression in prefrontal cortex of rats’ offspring submitted to prenatal ethanol …
  1224. Effect of water miscible organic solvents on p-nitrophenol hydroxylase (CYP2E1) activity in rat liver microsomes
  1225. Updated meta-analysis of the association between CYP2E1 RsaI/PstI polymorphisms and lung cancer risk in Chinese population
  1226. Transgenic plant regeneration of tobacco (Nicotiana tabacum) haboring mammalian CYP2E1 gene
  1227. Relationship of ALDH2 rs671 and CYP2E1 rs2031920 with hepatocellular carcinoma susceptibility in East Asians: a meta-analysis
  1228. Effect of BI-1 on insulin resistance through regulation of CYP2E1
  1229. Propolis alleviates 4‐aminobiphenyl‐induced oxidative DNA damage by inhibition of CYP2E1 expression in human liver cells
  1230. Protective effects of garlic oil against 1, 3-dichloro-2-propanol-induced hepatotoxicity: Role of CYP2E1 and MAPKs
  1231. Pyridoxine deficiency modulates benzene inhalation-induced hematotoxicity associated with hepatic CYP2E1 activity in B6C3F1 mice
  1232. Polymorphisms in alcohol dehydrogenase (ADH1) and cytochrome p450 2E1 (CYP2E1) genes in patients with cirrhosis and/or hepatocellular carcinoma
  1233. CYP2E1: the anesthesia enzyme
  1234. Meta-analysis of CYP2E1 polymorphisms in liver carcinogenesis
  1235. Pharmacological blockage of CYP2E1 and alcohol-mediated liver cancer: is the time ready?
  1236. CYP2E1 RsaI/PstI polymorphisms contributed to oral cancer susceptibility: a meta-analysis
  1237. Note of clarification of data on the association between CYP2E1 RsaI polymorphism and lung cancer risk
  1238. Environmental exposure to benzene: evaluation of urinary S-PMA and polymorphism (CYP2E1-1293G> C and NQO1 609C> T) in Campos Elíseos residents …
  1239. Dietary omega-3 polyunsaturated fatty acids alter fatty acid composition of lipids and CYP2E1 expression in rat liver tissue
  1240. CYP2E1 and ALDH2 gene polymorphisms in squamous cell head and neck Cancer in the Turkish population
  1241. Plasma cholinesterase activity is influenced by interactive effect between omethoate exposure and CYP2E1 polymorphisms
  1242. Study on inhibitory effect of water extract of Polygonum multiflorum on CYP1A2 and CYP2E1 enzymatic activities and mRNA expressions in rat liver
  1243. Effects of aqueous extract of Polygoni Multiflori Radix and its main constituents on expression of mRNA of CYP1A2, CYP2C9, and CYP2E1 in human liver L02 cells
  1244. Association between CYP2E1 genetic polymorphisms and urinary cancer risk: a meta-analysis
  1245. mRNA Expression of CYP2E1, CYP2A19, CYP1A2, HSD3B, SULT1A1 and SULT2A1 genes in surgically castrated, immunologically castrated, entire male and female …
  1246. Investigation of cytochrome p450 CYP1A2, CYP2D6, CYP2E1 and CYP3A4 gene expres-sions and polymorphisms in alcohol with-drawal
  1247. 2‐mercaptobenzothiazole generates γ‐H2AX via CYP2E1‐dependent production of reactive oxygen species in urothelial cells
  1248. CYP2E1-and TNFalpha/LPS-induced oxidative stress and MAPK signaling pathways in alcoholic liver disease
  1249. Study of CYP2E1 gene RsaI/PstI polymorphisms in patients with gastric cancer in north of Iran
  1250. Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity
  1251. Quantification of CYP2E1 in rat liver by UPLC-MS/MS-based targeted proteomics assay: a novel approach for enzyme activity assessment
  1252. Mechanism and clinical significance of HBx-mediated inhibition of CYP2E1 expression in the human HepG2 hepatoma cell line
  1253. Differences in butadiene adduct formation between rats and mice not due to selective inhibition of CYP2E1 by butadiene metabolites
  1254. Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells
  1255. Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients
  1256. Induction of rat hepatic CYP2E1 expression by arecoline in vivo
  1257. Ethanol-induced CYP2E1 Expression is Reduced by Lauric Acid via PI3K Pathway in HepG2 Cells
  1258. The physiological mechanism of improved formaldehyde resistance in Petunia hybrida harboring a mammalian CYP2E1 gene
  1259. Obesity‐induced CYP2E1 activity in children
  1260. CYP2E1, GSTM1, and GSTT1 genetic polymorphisms and their associations with susceptibility to antituberculosis drug-induced liver injury in Thai …
  1261. Mammalian CYP2E1 gene triggered changes of relative ions fluxes, CaM content and genes expression profiles in Petunia hybrida cells to enhance resistance to …
  1262. Losartan effects on liver cytochromes CYP3A, CYP2C and CYP2E1 functioning at metabolic syndrome in young and adult rats
  1263. All trans retinoic acid modulates TNF-α and CYP2E1 pathways and enhances regression of ethanol-induced fibrosis markers in hepatocytes and HSCs in abstaining …
  1264. CYP2E1 and Parkinson’s disease in a MPTP-induced C57BL/6 mouse model
  1265. End-product inhibition of skatole-metabolising enzymes CYP1A, CYP2A19 and CYP2E1 in porcine and piscine hepatic microsomes
  1266. ZSCAN25 and CYP2E1 polymorphisms is risk factors for ischemic stroke in a Chinese Han population: a case control study
  1267. CYP2E1 activity and children with obesity: possible confounding factors
  1268. Effects of SNPs (CYP1B1* 2 G355T, CYP1B1* 3 C4326G, and CYP2E1* 5 G-1293C), smoking, and drinking on susceptibility to laryngeal cancer among Han …
  1269. Exogenous toluene gas removal improvement in recombinant rabbit cytochrome P450 2E1 (CYP2E1)-transgenic Ardisia pusilla DC
  1270. CYP2E1 polymorphisms and colorectal cancer
  1271. Cytochrome P450 CYP2E1 Suppression Ameliorates Cerebral Ischemia Reperfusion Injury. Antioxidants 2021, 10, 52
  1272. Association of CYP2E1 and CYP1A1m2 (BsrD1) polymorphisms with cytogenetic biomarkers in petrol pump workers
  1273. Ephedra water decoction and cough tablets containing ephedra and liquorice induce CYP1A2 but not CYP2E1 hepatic enzymes in rats
  1274. Association of CYP1A1 and CYP2E1 gene polymorphisms with prostate cancer in a Lebanese population
  1275. Anti-tuberculosis drug-induced liver injury correlated with the methylation in the promoter regions of CYP2E1 and GSTM1
  1276. Unraveling CYP2E1 haplotypes in alcoholics from Central Brazil: a comparative study with 1000 genomes population
  1277. The effects of bovine serum albumin on kinetic characterization of human liver microsomal CYP2C19 and CYP2E1 activities
  1278. The effect of changes in CYP2E1 activity in the liver on toxicity and carcinogenicity of diethylnitrosamine in mice
  1279. Association of radiation risk in the second and third generations with polymorphisms in the genes CYP1A1, CYP2E1, GSTP1 and changes in the thyroid
  1280. Correction to: CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes
  1281. Modulation of CYP2E1 metabolic activity in a cohort of confirmed caffeine ingesting pregnant women with preterm offspring
  1282. M1 Polarization bias and subsequent NASH progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1 induced oxidative stress in …
  1283. Effect of Dietary Supplementation with Dried Tuber of Jerusalem Artichoke on Skatole Level in Backfat and CYP2E1 mRNA Expression in Liver of Boars
  1284. Roles of CYP2E1 in liver damage induced by 1, 2-dichloroethane
  1285. An improved in vitro method for screening toxin and medicine targeting CYP2E1
  1286. … : Nanoformulated SOD1 ameliorates the combined NASH and alcohol-associated liver disease partly via regulating CYP2E1 expression in adipose tissue and …
  1287. The Association of CYP2E1 Polymorphism and Environmental Factor in Nasopharyngeal Carcinoma Patients
  1288. Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?
  1289. Effect of Er Chen Tang on CYP2E1 and mitochondrial energy metabolism in nonalcoholic fatty liver disease
  1290. Requirement prediction for toluene detox with foods intake rich in CYP2E1 enzyme and glycine to prevent nerve and kidney damage at shoe home industry …
  1291. Association of CYP1A1 and CYP2E1 gene polymorphism with risk of arsenism caused by coal-burning
  1292. Insights into insulin-mediated regulation of CYP2E1: miR 132/212 targeting of CYP2E1 and role of PI3-K, Akt, mTOR signaling in regulating miR132/212 and miR 122 …
  1293. Polymorphisms of CYP2E1 rs2031920 is not Associated with Risk of Nasopharyngeal Carcinoma in Minangkabau Ethnic Group
  1294. Silver Nanoparticle-Doped Poly (8-Anilino-1-Naphthalene Sulphonic Acid)/CYP2E1 Nanobiosensor for Isoniazid-A First Line Anti-Tuberculosis Drug
  1295. Correlation between genetic polymorphisms of CYP2E1 DraⅠ and susceptibility of gastric cancer in Qinghai province
  1296. Genotype and phenotype polymorphisms of NAT2 and CYP2E1 in the Han Chinese pediatric population
  1297. Identification of Novel CYP2E1 Inhibitor to Investigate Cellular and Exosomal CYP2E1-Mediated Toxicity
  1298. Lack of association of CYP2E1 and CYP1A1 polymorphisms with osteoporosis in postmenauposal women
  1299. TRPV4 attenuates M1 polarization and subsequent NASH progression by stalling CYP2E1-mediated redox toxicity via eNOS.
  1300. Comment on:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”
  1301. Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like
  1302. Association between the TP53 and CYP2E1* 5B gene polymorphisms and non-small cell lung cancer
  1303. THE ROLE OF CYP2E1 POLYMORPHISM IN THE ACTIVATION OF PROCARCINOGEN METABOLISM OF NASOPHARYNGEAL CARCINOMA
  1304. CYP2E1 immunoglobulin G4 subclass antibodies after desflurane anesthesia
  1305. Effect of Capsosiphon fulvescens on ethanol-induced liver damage in HepG2 cells over expressing CYP2E1
  1306. Effect of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos before and after compatibility on activities of CYP1A2, CYP2E1, and CYP3A4 from rat liver …
  1307. Chemoprotective Effect of Daphnetin against Benzene Induced Leukemia Cancer via Alteration of CYP2E1
  1308. Modulatory effects of persimmon vinegar and its fractions on hepatic immune response and CYP2E1 activation in chronically alcohol drinking rats (649.4)
  1309. Ekspresija CYP2E1 u testisima štakora i alkoholom prouzrokovane promjene indeksa spermatogeneze i kolagena tipa I
  1310. Alcohol-Induced Increase in the Content of CYP2E1 in Human Liver Microsomes Causes a Multifold Activation of CYP3A4 and Attenuates its Cooperativity
  1311. CYP2E1 Associated Dysregulation of Nucleotide Excision Repair (NER) Process In Hepatocellular Carcinoma
  1312. Heliotropium undulatum attenuates hydrazine induced hepatotoxicity: involvement of cytochrome P450 CYP2E1 and oxidative stress
  1313. Maternal protein restriction during lactation modulated the expression and activity of rat offspring hepatic CYP1A1, CYP1A2, CYP2B1, CYP2B2, and CYP2E1 …
  1314. In Silico Approach for Hepatoprotective Activity of Piper crocatum Leaf Towards CYP2E1 Protein:(TJPS-2020-0154. R2)
  1315. Chronic ethanol and high glucose inducible CYP2E1 mediated oxidative stress leads to greater cellular injury in VL-17A cells: a potential mechanism for liver injury …
  1316. Extracts of Poria cocos polysaccharides improves alcoholic liver disease in mice via CYP2E1 and NF-κB inflammatory pathways
  1317. Liver Tissue-specific Genes IGFALS, CYP3A4, SLC22A1 and CYP2E1 May be Associated with Poor Prognosis of Liver Cancer
  1318. CYP2E1-DEPENDENT VARIATIONS IN HEPATOCYTES DAMAGE DURING TREATMENT OF TUBERCULOSIS
  1319. Higher CYP2E1 activity is a risk factor for hepatocarcinogenesis
  1320. Expression of CYP2E1 in different brain regions during the formation of toxic cerebral edema induced by 1, 2-DCE in mice and its effect on cerebral edema formation
  1321. Cloning and bioinformatics revealed molecular characterisation of CYP2E1 gene from bactrian camel (Camelus bactrianus)
  1322. Hepatotoxicity Risk Profile of Indonesian Due to Polymorphism of NAT2 and CYP2E1 in Isoniazid Metabolism
  1323. The Polymorphism and Expression of CYP2E1 Gene and Its Relation to Carcass and Meat Quality of Indonesian Lamb
  1324. The regulation of CYP2E1 gene expression and its role in breast cancer
  1325. Effect of grapefruit juice on CYP2E1 gene expression in obese and control rats
  1326. CYP2E1 mediated ethanol metabolism in ARPE-19 cells.
  1327. Correction: Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis
  1328. Non-additive effects of changing the cytochrome P450 ensemble: incorporation of CYP2E1 into human liver microsomes and its impact on CYP1A2
  1329. The correlation between CYP2E1 and CYP1A1 genotypes with the susceptibility of HBV infection in northern Guangzhou people
  1330. COMPARISON OF POLYMORPHISM rs2070672 CYP2E1 GENE PROPORTION IN EARLY AND ADVANCED STAGE OF UNDIFFERENTIATED TYPE …
  1331. Crosstalk between CYP2E1 and CYP3A enzymes and its Possible Involvement in Alcohol-Drug Interactions.
  1332. MicroRNA‐122 protects mice and human hepatocytes from acetaminophen toxicity by regulating CYP1A2 and CYP2E1 expression
  1333. Evaluation of smoke burning AnbarNesara on changes of the gene expression of P53 and CYP2E1 in human liver cancer cells
  1334. Profile of retinal pigment epithelium response to ethanol: Role of CYP2E1
  1335. CYP2E1 activity on ARPE-19 cells: New approach to RPE ethanol metabolism
  1336. Povezanost polimorfizama gena TP53 i CYP2E1* 5B s nemikrocelularnim karcinomom pluća
  1337. Relationship between CYP2E1 genetic polymorphism and susceptibility of gastric cancer in Hakkaness
  1338. Bioinformatic Analysis of the Main Characteristics and Structure of the Gene Encoding CYP2E1 Protein.
  1339. Response: Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?
  1340. … Protects Hepato-Renal Tissues Against Antituberculosis Drugs Induced Toxic Manifestations by Modulating IL-6, IGF-1, CYP2E1, Biochemical and Ultra …
  1341. Expression of CYP2E1 gene in paint workers occupationally exposed to organic solvents
  1342. Results of intensive phase tretament of tuberculosis treatment according to CYP2E1 genotype
  1343. Association of CYP2E1 Gene Polymorphisms with the Risk of Schizophrenia in the Bangladeshi Population
  1344. Expression of CYP2E1 gene in paint workers occupationally exposed to organic solvents
  1345. Enhanced Hepatotoxicity of Extract of Polygoni Multiflori Radix after Inhibition of CYP2E1 and Screening of Toxic Constituents
  1346. Functional correlate of CYP2E1 methylation in chronic exposure to VOCs: promoter methylation vs. 5’UTR methylation
  1347. CYP2E1 recovery is associated with a pericentral fibrosis pattern after repeated CCl4 insults
  1348. Polymorphisms of CYP2E1 rs2031920 is not Associated with Risk of Nasopharyngeal Carcinoma in Minangkabau Ethnic Group. Open Access Maced J Med Sci …
  1349. CYP2E1 activity in cisplatin resistant cancer cells
  1350. Effect of temperature on carp CYP2E1-like isoform activity.
  1351. The Meta Isomer of Acetaminophen Is A Time Dependent Inhibitor of Human CYP2E1
  1352. CYP2E1 substrate inhibition. MECHANISTIC INTERPRETATION THROUGH AN EFFECTOR SITE FOR MONOCYCLIC COMPOUNDS.
  1353. The Oxidative Effect Of Nlrp3 And CYP2E1 In Development Of Renal Failure Associated With Hypertension And Diabetes Mellitus Diseases
  1354. UPREGULATING OF CYP2E1 IN ETHANOL-FED MICE WITH TRANSGENIC OVEREXPRESSION OF CTRP3
  1355. Distribution of single nucleotide polymorphisms of CYP2E1 gene in Congjiang Xiang-pigs.
  1356. Genetic Polymorphism in Promoter Sequence of CYP2E1 Gene in Paint Manufacturing Workers Exposed to Volatile Organic Compounds
  1357. Computational Docking Simulations of Nitroanisole and Nitrophenol with CYP2E1
  1358. TRPV4 Modulates CYP2E1 Function in Nonalcoholic Steatohepatitis Progression
  1359. Genotype and allelic frequencies of CYP2E1* 5B polymorphism in the southwest population of Iran
  1360. Effects of trichloroethylene toxicity on normal human liver cells and hepatocytes with CYP2E1 gene overexpression
  1361. Assessing specificity of indazole derivatives as inhibitors to CYP2E1
  1362. Effects of three kinds of tea beverages on intestinal first-pass effect and liver Cyp3a, CYP2E1 activities in mice
  1363. Nicotinamide N-Oxidation by CYP2E1 in Human Liver Microsomes
  1364. Association of genetic polymorphisms of CYP2E1 and MPO genes with acute leukemia risk: a meta-analysis.
  1365. Effect of Jiangzhiligan Granules on CYP2E1 Gene and Protein Expression of Rat Model with Non-alcoholic Fatty Liver Disease
  1366. Identification of deletions and duplications in the CYP2E1 gene in a population in Goiânia–GO by MLPA.
  1367. Effects of Mailuoning injection on rat activities of CYP1A2, CYP2E1 and CYP3A4 using a three-drug Cocktail approach
  1368. Requirement Prediction for Toluene Detox with Foods Intake Rich in CYP2E1 Enzyme and Glycine to Prevent Nerve and Kidney Damage at Shoe Home …
  1369. CYP2E1 Epigenetic Regulation In Workers Exposed To Low-Level Voc Mixture: Relationship With Nitrosative Stress And Inflammation
  1370. The Inhibitory Effect of the Derris scandens Extract on Cytochrome P450 2E1 (CYP2E1)-associated Aniline-4-Hydroxylase in vitro
  1371. Association of CYP2E1 and CYP1A1m2 (BsrD1) polymorphisms with cytogenetic biomarkers in petrol pump workers
  1372. The Physiological Mechanism of Petunia hybrida Harboring Mammalian CYP2E1 Gene Improving Resistance to Formaldehyde
  1373. Non‐Additive Effects of Changing the Composition of the Cytochrome P450 Ensemble in Human Liver Microsomes: the Focus on CYP2E1 and Alcohol‐Drug …
  1374. Higher chlorzoxazone clearance in obese children compared with none-obese peers, an open-label explorative pharmacokinetic study of CYP2E1 activity
  1375. Cytochrome CYP2E1 is critical for joint effects of alcohol and lipids on hepatocellular steatosis and inflammation
  1376. CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population
  1377. A study on the effects of Lauric acid on ROS formation and CYP2E1 mRNA expression in alcohol-induced HEPG2 cells
  1378. Research on Association of Genetic Polymorphism of CYP1A1 and CYP2E1, with Susceptibility to Gastric Cancer
  1379. CYP2E1 VNTR genotyping associated to anti–tuberculosis drug-induced hepatotoxicity
  1380. Study on CYP2E1 gene polymorphism and the relationship between methylation level of its promoter region and liver injury induced by anti-tuberculosis drugs in …
  1381. Relative contribution of hepatic CYP3A and CYP2E1 to oxidative stress upon CHIP E3 ligase knockdown
  1382. Effect of Neiyixiao on Hepatic CYP1A2, CYP2E1, CYP3A4 in Rats with Endometriosis
  1383. Bioinformatics of CYP2E1 CpG intron methylation sites and application to HAR1-RELN sequence analysis
  1384. Effect of flavonoids extract from apocynum venetum tea on CYP2E1 in mice.
  1385. CYP2E1 is a central mediator for the synergistic effects of alcohol and free fatty acids on hepatocellular steatosis and inflammation
  1386. Acetaminophen and Isoniazid treatment leads to oxidative stress and cytotoxicity in cerebellar granule neurons possibly by CYP2E1 activation
  1387. Drinking Water Chlorination By-Products and Intra-Uterine Growth Restriction: is there an effect modification of the CYP2E1 G1259C gene polymorphism?
  1388. CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis
  1389. Study the Correlation of GSTM1 and CYP2E1 Gene Polymorphism and Genetic Susceptibility to Non-small Cell Lung Cancer in Shenzhen Area
  1390. CONTROL OF BOAR TAINT BY USING GENETIC MARKERS: A SINGLE NUCLEOTIDE POLYMORPHISM IN THE CYP2E1 GENE PROMOTER AFFECTS …
  1391. Binge alcohol promotes acute liver injury through a CYP2E1‐HIF‐1α‐dependent apoptosis pathway in mice and humans (1010.1)
  1392. Effects of cefetamet hydrochloride injection on activity of CYP1A2, CYP3A4 and CYP2E1 in liver microsomes of rats
  1393. Evaluation of genotoxicity of environmental contaminants, production of bio-sensor cell lines and measurment of CYP2E1 enzymatic activity
  1394. B107 TUBERCULOSIS: ISSUES DURING TREATMENT: An Updated Meta-Analysis On CYP2E1 Rsai/psti And Drai Polymorphisms And Risk Of Anti-Tuberculosis …
  1395. An Updated Meta-Analysis On CYP2E1 RsaI/PstI And DraI Polymorphisms And Risk Of Anti-Tuberculosis Induced Hepatotoxicity: Evidence From 26 Studies
  1396. Analysis of Protein and mRNA Expressions of CYP1A1 and CYP2E1 Enzymes In Liver, Colon And Prostate Cancer Cell Lines to Study Drug and Carcinogen …
  1397. Correction: Investigation of Indazole Unbinding Pathways in CYP2E1 by Molecular Dynamics Simulations
  1398. Polimorfismos nos genes NAT2, CYP2E1, GSTT1, GSTM1 e ABCB11 e hepatotoxicidade induzida pela isoniazida
  1399. GENOTYPE POLYMORPHISMS OF NAT2 AND CYP2E1 GENES ASSOCIATED WITH DRUG INDUCED LIVER INJURY (DILI) IN INDONESIAN …
  1400. Effects of nonyphenol exposure during pregnant and lactation period on expressions of CYP2E1 mRNA and protein of hepatic tissues in offspring rats.
  1401. Modulatory effects of persimmon vinegar and its fractions on alcohol-induced inflammatory stress and CYP2E1 expressions in the liver of Wistar rats
  1402. CYP2E1 rs2031920, COMT rs4680 Polymorphisms, Cigarette Smoking, Alcohol Use and Lung Cancer Risk in a Japanese Population
  1403. The role of brain acetaldehyde in drinking preference: Genetic modification of alcohol oxidizing enzymes catalase and CYP2E1 in C57BL/6 mice and their …
  1404. The effect of organic solvents and CYP1A1, CYP2E1, GSTM1 polymorphisms on the development of acute lymphoblastic leukemia in Quebec children
  1405. Nonclassical ROR Alpha Pathway Switches Transcriptional Mode of ERR Gamma that Results in Repression of Alcohol-induced CYP2E1 Expression
  1406. Effects of the plant phenolic quercetin on protein and mRNA CYP1A1, CYP2E1, NQO1 and GST enzymes in colon cancer cell line SW620
  1407. Analysis of protein and mRNA expressions of CYP1A1, CYP2E1, NQO1 and GST enzymes in liver, colon and prostate cancer cell lines to study drug and carcinogen …
  1408. Analysis of ethanol metabolic enzymes in primary human mammary epithelial cells and MCF‐10A cells: possible participation of CYP2E1 in ethanol‐induced oxidative …
  1409. Hepatoprotective Activity of Eugenol, Hesperidin and Lepidium Sativum Alkaloids in Rats with Liver Injury through Attenuating CYP2E1/Nuclear Factor Kappa-B and …
  1410. S29. 1 CORRELATION BETWEEN SPERMATOGENESIS DISORDERS AND CYP2E1 MRNA EXPRESSION IN RATS TESTES FOLLOWING CHRONIC …
  1411. ISALPDC-03: CYP2E1 Regulation of Ethanol-Induced Intestinal miRNAs in Liver Injury
  1412. Comparison of Polymorphism rs3813865 Cytochrome P450 Family 2 Subfamily E Polypeptide 1 (CYP2E1) Gene in Various Clinical Stage of Undifferentiated …
  1413. 0466 The effect of SNPs in the promoter on expression of CYP2E1 gene and boar taint
  1414. Author’s Reply to Reith:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”
  1415. Regulation of il-1 and TNF-α on metabolic enzyme CYP2E1 in immunological liver injury in rats
  1416. … ALCOHOL AND CANCER SY05-1 CARCINOGENIC ETHENO DNA ADDUCTS GENERATED DURING INFLAMMATION AND CYP2E1 INDUCTION IN VARIOUS …
  1417. Author Correction: Effect of BI-1 on insulin resistance through regulation of CYP2E1
  1418. Correction to The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65
Share
0
INTERSTELLAR BLEND

Related posts

September 24, 2022

ANXIOGENIC


Read more
September 24, 2022

EPIGENETIC ALTERATIONS


Read more
September 24, 2022

EXTRACELLULAR MICROVESICLES


Read more

Comments are closed.

© 2023 Betheme by Muffin group | All Rights Reserved | Powered by WordPress
    ✕

    Login

    Lost your password?

    Create an account?