CYP2E1 | Interstellar Blends | Activate Your Super Powers!

Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: evidence that CYP2E1 possesses a rapid phase half …

Development and properties of HepG2 cells that constitutively express CYP2E1

Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol

CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis

Human CYP2E1 mediates the formation of glycidamide from acrylamide

Role of CYP2E1 in the epoxidation of acrylamide to glycidamide and formation of DNA and hemoglobin adducts

CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane

Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics

Iron and CYP2E1-dependent oxidative stress and toxicity

Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis

Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity

Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1.

Diallylsulfide and allylmethylsulfide are uniquely effective among organosulfur compounds in inhibiting CYP2E1 protein in animal models

CYP2E1‐mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells

In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians.

CYP2E1-dependent toxicity and up-regulation of antioxidant genes

Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1

Polymorphisms in GSTT1, GSTZ1, and CYP2E1, Disinfection By-products, and Risk of Bladder Cancer in Spain

Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1

Mechanisms of down-regulation of CYP2E1 expression by inflammatory cytokines in rat hepatoma cells

Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect

Advances in the interpretation and prediction of CYP2E1 metabolism from a biochemical perspective

Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia

Cytochrome P450IIE1 (CYP2E1) is induced by skatole and this induction is blocked by androstenone in isolated pig hepatocytes

Association of CYP2E1 gene polymorphism with predisposition to cancer development

CYP2E1 substrate inhibition: Mechanistic interpretation through an effector site for monocyclic compounds

Transcriptional control of the rat hepatic CYP2E1 gene

Transcriptional control of CYP2E1 in the perivenous liver region and during starvation

Mechanism-based inactivation of human CYP2E1 by diethyldithocarbamate

Nrf2 and antioxidant defense against CYP2E1 toxicity

Acetaldehyde as well as ethanol is metabolized by human CYP2E1

NAT2 and CYP2E1 polymorphisms and susceptibility to first-line anti-tuberculosis drug-induced hepatitis

Associations of CYP1A1, GSTM1, and CYP2E1 Polymorphisms with Lung Cancer Suggest Cell Type Specificities to Tobacco Carcinogens

Pharmacokinetic consequences of induction of CYP2E1 by ligand stabilization

Activity of CYP2E1 and CYP3A enzymes in adults with moderate alcohol consumption: a comparison with nonalcoholics

Loss of CYP2E1 and CYP1A2 activity as a function of acetaminophen dose: relation to toxicity

Acetone catabolism by cytochrome P450 2E1: studies with CYP2E1-null mice

Genetic polymorphisms of CYP2E1, GSTM1, and GSTT1; environmental factors and risk of oral cancer.

Regulation of CYP2E1 by ethanol and palmitic acid and CYP4A11 by clofibrate in primary cultures of human hepatocytes

Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1

Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1

CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophaghy in HepG2 E47 cells

Effects of rifampin on CYP2E1-dependent hepatotoxicity of isoniazid in rats

CYP2E1 activity in patients with alcoholic liver disease

Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen

CYP2E1-dependent oxidative stress and toxicity: role in ethanol-induced liver injury

Lipid peroxidation, CYP2E1 and arachidonic acid metabolism in alcoholic liver disease in rats

CYP2E1-mediated modulation of valproic acid-induced hepatocytotoxicity

Genetic Polymorphisms of CYP2E1 and Risk of Colorectal Cancer: The Fukuoka Colorectal Cancer Study

Genetic polymorphism of GSTM1, CYP2E1 and CYP2D6 in Egyptian bladder cancer patients

Cytochrome P450 2E1 (CYP2E1) is essential for acrylonitrile metabolism to cyanide: comparative studies using CYP2E1-null and wild-type mice

Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components

Expression of CYP2E1 during human fetal development: methylation of the CYP2E1 gene in human fetal and adult liver samples

CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of γ-glutamylcysteine synthetase

Genetic polymorphisms of NAT2, CYP2E1 and GST enzymes and the occurrence of antituberculosis drug-induced hepatitis in Brazilian TB patients

Genotype and allele frequencies of polymorphic CYP2E1 in the Turkish population

The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage

Ethanol induction of CYP2A5: permissive role for CYP2E1

Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse

Acetaldehyde as a substrate for ethanol-inducible cytochrome P450 (CYP2E1)

Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice

CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people

Red Meat Intake, CYP2E1 Genetic Polymorphisms, and Colorectal Cancer Risk

Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1

Comparison of germ cell mutagenicity in male CYP2E1-null and wild-type mice treated with acrylamide: evidence supporting a glycidamide-mediated effect

Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver

Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and CYP2E1 (–/–) mice

Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes

Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione

Induction of catalase, alpha, and microsomal glutathione S‐transferase in CYP2E1 overexpressing HepG2 cells and protection against short‐term oxidative stress

Tissue-specific expression and methylation of the human CYP2E1 gene

Evaluation of caffeine as a test drug for CYP1A2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations.

Induction and recovery time course of rat brain CYP2E1 after nicotine treatment

Histone modification-mediated CYP2E1 gene expression and apoptosis of HepG2 cells

Genetic variations of NAT2 and CYP2E1 and isoniazid hepatotoxicity in a diverse population

Association between CYP2E1 genetic polymorphisms and lung cancer risk: a meta-analysis

Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous system

Genetic polymorphisms in GSTM1,-P1,-T1, and CYP2E1 and the risk of adult brain tumors

The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphisms in a Finish study population

Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation

Synergistic toxicity of iron and arachidonic acid in HepG2 cells overexpressing CYP2E1

Post-transcriptional regulation of rat CYP2E1 expression: role of CYP2E1 mRNA untranslated regions in control of translational efficiency and message stability

Ethanol‐mediated carcinogenesis in the human esophagus implicates CYP2E1 induction and the generation of carcinogenic DNA‐lesions

Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and CYP2E1 …

Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation

Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian …

Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias

Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single ingestion of watercress

Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole

Elucidation of CYP2E1 5′ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer

The role of CYP2E1 and 2B1 in metabolic activation of benzene derivatives

The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis

Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling

Construction and assessment of models of CYP2E1: predictions of metabolism from docking, molecular dynamics, and density functional theoretical calculations

Acetoacetate induces CYP2E1 protein and suppresses CYP2E1 mRNA in primary cultured rat hepatocytes

The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: effect on age of presentation and dependence on alcohol …

Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis

Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression

Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1

Constitutive and inducible expression of hepatic CYP2E1 in leptin-deficient ob/ob mice

Study of polymorphisms in the CYP2E1 gene in patients with alcoholic pancreatitis

The GST T1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function

Role of the Liver-Enriched Transcription Factor HNF-1α in Expression of the CYP2E1 Gene

Ontogeny of hepatic CYP1A2 and CYP2E1 expression in rat

Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo

Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice

Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol‐induced oxidative DNA damage in rodent liver

The effect of ethanol-induced CYP2E1 on proteasome activity: the role of 4-hydroxynonenal

Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine

Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning.

Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome?

Genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 associated with head and neck cancer

Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats

Risk assessment: toxicity from chemical exposure resulting from enhanced expression of CYP2E1

… for the Expression of Recombinant Human Cytochrome P450s inEscherichia coliUsing Bacterial Signal Peptides: Expression of CYP3A4, CYP2A6, and CYP2E1

Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver

Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in Chinese Han populations from four different geographic areas of Mainland China

Transgenic alfalfa plants co-expressing glutathione S-transferase (GST) and human CYP2E1 show enhanced resistance to mixed contaminates of heavy metals and …

Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1

Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers …

Construction of a CYP2E1-template system for prediction of the metabolism on both site and preference order

Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes

Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1

CYP2E1 is preferentially expressed in Clara cells of murine lung: localization by in situ hybridization and immunohistochemical methods.

NQO1, MPO, CYP2E1, GSTT1 and GSTM1 polymorphisms and biological effects of benzene exposure—a literature review

Spectrophotometric Analysis of Human CYP2E1-Catalyzed p-Nitrophenol Hydroxylation

An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A)

Heteromeric complex formation between CYP2E1 and CYP1A2: evidence for the involvement of electrostatic interactions

CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation

Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1, 3-dimethyluric acid formation

Inhibition of CYP2E1 Reverses CD4+ T-Cell Alterations in Trichloroethylene-Treated MRL+/+ Mice

Genetic polymorphisms of CYP2D6, CYP1A1 and CYP2E1 in the South-Amerindian population of Chile.

Amelioration of oxidative stress by dandelion extract through CYP2E1 suppression against acute liver injury induced by carbon tetrachloride in sprague‐dawley rats

CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes

St. John’s wort extract induces CYP3A and CYP2E1 in the Swiss Webster mouse

Effect of antifungal drugs on cytochrome P450 (CYP) 1A2, CYP2D6, and CYP2E1 activities in human liver microsomes

Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine

Combined analysis of germline polymorphisms of p53, GSTM1, GSTT1, CYP1A1, and CYP2E1: relation to the incidence rate of cervical carcinoma

Immunohistochemical demonstration of the expression of CYP2E1 in human breast tumour and non-tumour tissues

Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro

Genetic polymorphisms in cytochrome P450 (CYP) 1A1, CYP1A2, CYP2E1, glutathione S-transferase (GST) M1 and GSTT1 and susceptibility to prostate cancer in the …

Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene

A significantly joint effect between arsenic and occupational exposures and risk genotypes/diplotypes of CYP2E1, GSTO1 and GSTO2 on risk of urothelial carcinoma

CYP2E1 regulation by benzene and other small organic chemicals in rat liver and peripheral lymphocytes

Metabolic oxidation and toxification of N-methylformamide catalyzed by the cytochrome P450 isoenzyme CYP2E1.

Differential Modulation of CYP2E1 Activity by CAMP-Dependent Protein Kinase upon Ser129Replacement

Kinetic characterization of CYP2E1 inhibition in vivo and in vitro by the chloroethylenes

Translational activation of ethanol-inducible cytochrome P450 (CYP2E1) by isoniazid

Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations

Distribution and differential induction of CYP2E1 by ethanol and acetone in the mesocorticolimbic system of rat

Identification and characterization of a mitochondrial targeting signal in rat cytochrome P450 2E1 (CYP2E1)

Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using CYP2E1-/-mice

CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling

Analysis of CYP2E1 polymorphism for the determination of genetic susceptibility to gastric cancer in Koreans

Obesity-induced increase of CYP2E1 activity and its effect on disposition kinetics of chlorzoxazone in Zucker rats

Lung cancer risk in relation to the CYP2E1 Rsa I genetic polymorphism among African-Americans and Caucasians in Los Angeles County.

Polymorphism in CYP1A1 and CYP2E1 genes and susceptibility to leukoplakia in Indian tobacco users

Early Alcoholic Liver Injury: Formation of Protein Adducts with Acetaldehyde and Lipid Peroxidation Products, and Expression of CYP2E1 AND CYP3A

Frequencies of genotypes and alleles of the functional SNPs in CYP2C19 and CYP2E1 in mainland Chinese Kazakh, Uygur and Han populations

CYP1A1 CYP2E1 and GSTM1 polymorphisms are not associated with susceptibility to squamous‐cell carcinoma of the esophagus

Influence of CYP1A1, CYP2E1, GSTM3 and NAT2 genetic polymorphisms in oral cancer susceptibility: results from a case-control study in Rio de Janeiro

Effects of cytochrome P450 (CYP) 2A6 gene deletion and CYP2E1 genotypes on gastric adenocarcinoma

Involvement of CYP2E1 as a low-affinity enzyme in phenacetin O-deethylation in human liver microsomes

Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice

Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH …

Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity

A Novel Polymorphism rs1329149 of CYP2E1 and a Known Polymorphism rs671 of ALDH2 of Alcohol Metabolizing Enzymes Are Associated with Colorectal Cancer …

Association of CYP2E1 and NAT2 gene polymorphisms with chronic obstructive pulmonary disease

CYP2A6 and CYP2E1 polymorphisms in a Brazilian population living in Rio de Janeiro

Microsomal ethanol oxidizing system: transcriptional and posttranscriptional regulation of cytochrome P450, CYP2E1.

Mitochondrial dysfunction by γ-irradiation accompanies the induction of cytochrome P450 2E1 (CYP2E1) in rat liver

Role of CYP2E1 genotypes in susceptibility to colorectal cancer in the Kashmiri population

Acetaldehyde generating enzyme systems: roles of alcohol dehydrogenase, CYP2E1 and catalase, and speculations on the role of other enzymes and processes

Inactivation of stress protein p8 increases murine carbon tetrachloride hepatotoxicity via preserved CYP2E1 activity

Lycopene attenuates alcoholic apoptosis in HepG2 cells expressing CYP2E1

CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90

CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell …

Induction of nicotine-metabolizing CYP2B1 by ethanol and ethanol-metabolizing CYP2E1 by nicotine: summary and implications

Expression of CYP2E1 in human nasopharynx and its metabolic effect in vitro

Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity

Genetic Polymorphisms of ADH1C and CYP2E1 and Risk of Oral Squamous Cell Carcinoma

Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations

CYP2E1 expression in human lymphocytes from various ethnic populations

Association between CYP2E1 polymorphisms and susceptibility to prostate cancer

CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases …

CYP2E1-dependent benzene toxicity: the role of extrahepatic benzene metabolism

The effects of alcohol and diallyl sulphide on CYP2E1 activity in humans: a phenotyping study using chlorzoxazone

Distribution of ADH1B, ALDH2, CYP2E1∗ 6, and CYP2E1∗ 7B genotypes in Turkish population

The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells

Genetic polymorphism of CYP2E1, ADH2, and ALDH2 in Mexican-Americans

Effect of ALDH2 and CYP2E1 Gene Polymorphisms on Drinking Behavior and Alcoholic Liver Disease in Japanese Male Workers

Tandem Repeat Polymorphism of the CYP2E1 Gene: An Association Study With Esophageal Cancer and Lung Cancer

The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone

CYP1A2* 1C, CYP2E1* 5B, and GSTM1 polymorphisms are predictors of risk and poor outcome in head and neck squamous cell carcinoma patients

Polymorphisms in glutathione S‐transferases GSTM1, GSTT1 and GSTP1 and cytochromes P450 CYP2E1 and CYP1A1 and susceptibility to cirrhosis or …

DNA damage and cytotoxicity in pancreatic β-cells expressing human CYP2E1

Cytochrome P4502E1 (CYP2E1) expression in peripheral blood lymphocytes: evaluation in hepatitis C and diabetes

Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the …

Pharmacokinetics of chlorzoxazone in rats with diabetes: induction of CYP2E1 on 6-hydroxychlorzoxazone formation

Significance of genetic polymorphisms at multiple loci of CYP2E1 in the risk of development of childhood acute lymphoblastic leukemia

The effect of isoniazid on CYP2E1-and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney

Immunohistochemical study of CYP2E1 in hepatocellular carcinoma carcinogenesis: examination with newly prepared anti-human CYP2E1 antibody

Human hepatocytes are protected from ethanol-induced cytotoxicity by DADS via CYP2E1 inhibition

Genetic polymorphism of the CYP1A1, CYP2E1, GSTM1 and GSTT1 genes and lung cancer susceptibility in a north Indian population

Cytochrome CYP2E1 phenotyping and genotyping in the evaluation of health risks from exposure to polluted environments

Growth retardation of fetal rats exposed to nicotine in utero: Possible involvement of CYP1A1, CYP2E1, and P‐glycoprotein

Association of GSTM1, CYP1A1 and CYP2E1 genetic polymorphisms with susceptibility to lung adenocarcinoma: A case‐control study in Chinese population

Induction of hepatic CYP2E1 by a subtoxic dose of acetaminophen in rats: increase in dichloromethane metabolism and carboxyhemoglobin elevation

CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking

The impact of CYP2E1 genetic variability on risk assessment of VOC mixtures

Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in rats

Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism

CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism

Global Analysis of Protein− Protein Interactions Reveals Multiple CYP2E1− Reductase Complexes

Differential role of CYP2E1 binders and isoniazid on CYP2E1 protein modification in NADPH-dependent microsomal oxidative reactions: free radical scavenging …

Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity

Polymorphisms of CYP1a1, CYP2E1, GSTM1, GSTT1, and TP53 genes in Amerindians

CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head and …

CYP2E1 Rsa I/Pst I polymorphism is associated with lung cancer risk among Asians

The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes

Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions

A Case–control and a family-based association study revealing an association between CYP2E1 polymorphisms and nasopharyngeal carcinoma risk …

Functional polymorphism in porcine CYP2E1 gene: Its association with skatole levels

Identification of CYP2E1 in marmoset monkey

Effects of diabetes on rabbit kidney and lung CYP2E1 and CYP2B4 expression and drug metabolism and potentiation of carcinogenic activity of N …

Does CYP2E1 play a major role in the aggravation of isoniazid toxicity by rifampicin in human hepatocytes?

Relationship between genetic polymorphisms of metabolizing enzymes CYP2E1, GSTM1 and Kazakh’s esophageal squamous cell cancer in Xinjiang, China

ADH2 and CYP2E1 genetic polymorphisms: risk factors for alcohol-related birth defects

Renal and hepatic accumulation of cadmium and lead in the expression of CYP4F2 and CYP2E1

Ageing is associated with increased expression but decreased activity of CYP2E1 in male Wistar rats

Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity

Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system

Effect of cigarette smoke on hepatic and pulmonary cytochromes P450 in mouse: evidence for CYP2E1 induction in lung

CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese

Effect of fasting and obesity in humans on the 6‐hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity

Benzene-induced genotoxicity in mice in vivo detected by the alkaline comet assay: reduction by CYP2E1 inhibition

Adverse Birth Outcomes Associated with Maternal Smoking and Polymorphisms in the N-Nitrosamine-Metabolizing Enzyme Genes NQO1 and CYP2E1

NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species

Hypomethylation and hypoexpression of human CYP2E1 gene in lung tumors

GSTT1 and CYP2E1 polymorphisms and trihalomethanes in drinking water: effect on childhood leukemia.

Inhibition of CYP2E1 with natural agents may be a feasible strategy for minimizing the hepatotoxicity of ethanol

A High Throughput Screening Assay to Screen for CYP2E1 Metabolism and Inhibition Using a Fluorogenic Vivid® P450 Substrate

Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1

GSTT1, GSTM1 and CYP2E1 genetic polymorphisms in gastric cancer and chronic gastritis in a Brazilian population

A temporal study on the histopathological, biochemical and molecular responses of CCl4-induced hepatotoxicity in CYP2E1-null mice

Effects of Ganoderma lucidum polysaccharide on CYP2E1, CYP1A2 and CYP3A activities in BCG-immune hepatic injury in rats

Expression of CYP2E1 in Human Lung and Kidney during Development and in Full‐Term Placenta: A Differential Methylation of the Gene is Involved in the …

Comparative metabolism and disposition of trichloroethylene in CYP2E1–/–and wild-type mice

Inhibition of cytochrome P450 enzymes participating in p-nitrophenol hydroxylation by drugs known as CYP2E1 inhibitors

Chlorzoxazone as a single sample probe of hepatic CYP2E1 activity in humans

Kupffer cell inactivation alleviates ethanol-induced steatosis and CYP2E1 induction but not inflammatory responses in rat liver

Protective effects of emodin and chrysophanol isolated from marine fungus Aspergillus sp. on ethanol-induced toxicity in HepG2/CYP2E1 cells

Association of combined CYP2E1 gene polymorphism with the risk for esophageal squamous cell carcinoma in Huai’an population, China

Covalent immobilization of recombinant human cytochrome CYP2E1 and glucose-6-phosphate dehydrogenase in alumina membrane for drug screening applications

Promoter function and the role of cytokines in the transcriptional regulation of rabbit CYP2E1 and CYP2E2

Differential effects of diabetes on CYP2E1 and CYP2B4 proteins and associated drug metabolizing enzyme activities in rabbit liver

… exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 …

Relationship between alcoholism and CYP2E1 C/D polymorphism

Polymorphism of metabolizing genes and lung cancer histology: prevalence of CYP2E1 in adenocarcinoma

Differential effects of dietary fatty acids on the regulation of CYP2E1 and protein kinase C in human hepatoma HepG2 cells

Cytochrome P4502E1 (CYP2E1) genetic polymorphism in a case-control study of gastric cancer and liver disease.

Lymphocyte cytochrome P450-CYP2E1 expression in human IDDM subjects

Role of calcium and calcium-activated proteases in CYP2E1-dependent toxicity in HEPG2 cells

Oxidative stress potentiated by diallylsulfide, a selective CYP2E1 inhibitor, in isoniazid toxic effect on rat primary hepatocytes

Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP2E1, GSTM1, and NAT2), drinking habits, histological subtypes, and p53 …

The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin

Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1

Helicobacter pylori infection, but not genetic polymorphism of CYP2E1, is highly prevalent in gastric cancer patients younger than 40 years

Role of CYP2E1 immunoglobulin G4 subclass antibodies and complement in pathogenesis of idiosyncratic drug-induced hepatitis

A negative cooperativity mechanism of human CYP2E1 inferred from molecular dynamics simulations and free energy calculations

Hormone controlled phosphorylation and degradation of CYP2B1 and CYP2E1 in isolated rat hepatocytes

Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue

Genetic polymorphism of the CYP2E1 gene and susceptibility to Parkinson’s disease in Taiwanese

Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity

Differential in vivo effects of α‐naphthoflavone and β‐naphthoflavone on CYP1A1 and CYP2E1 in rat liver, lung, heart, and kidney

cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse CYP2E1

… and CYP2E1 and N‐terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae − role of protein kinase A in the mitochondrial targeting of CYP2E1

CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk: a meta-analysis

Lipopolysaccharide induces CYP2E1 in astrocytes through MAP kinase kinase-3 and C/EBPβ and-δ

Inhibition of urethane-induced genotoxicity and cell proliferation in CYP2E1-null mice

Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1–JNK1 pathway in HepG2 cells

Theoretical study of the mechanism of acetaldehyde hydroxylation by compound I of CYP2E1

Molecular modelling of CYP2E1 enzymes from rat, mouse and man: an explanation for species differences in butadiene metabolism and potential carcinogenicity, and …

The molecular mechanism regulating 24‐hour rhythm of CYP2E1 expression in the mouse liver

Ethanol‐related cytotoxicity catalyzed by CYP2E1‐dependent generation of reactive oxygen intermediates in transduced HepG2 cells

Validation of the (ω-l)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1

The ADH3* 2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men

Interindividual variability of chlorzoxazone 6‐hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms

Impact of CYP2E1 genotype in renal cell and urothelial cancer patients

Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage

Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1

Role of CYP2E1 activity in endoplasmic reticulum ubiquitination, proteasome association, and the unfolded protein response

Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes

Distribution of cytochrome CYP2E1 in murine liver after ethanol and acetone administration

Contribution of CYP2E1 to N-methyl-2-pyrrolidone metabolism

Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration.

Phenobarbital induces monkey brain CYP2E1 protein but not hepatic CYP2E1, in vitro or in vivo chlorzoxazone metabolism

Ethanol-induced oxidative DNA damage and CYP2E1 expression in liver tissue of Aldh2 knockout mice

Modification of CYP2E1 and CYP3A4 activities in haemoglobin E-beta thalassemia patients

Changes of CYP2E1 activity in diabetic rat model

Use of molecular simulation for mapping conformational CYP2E1 epitopes

Ethanol enhanced the genotoxicity of acrylamide in human, metabolically competent HepG2 cells by CYP2E1 induction and glutathione depletion

Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene

The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine

Differential metabolism of acrylonitrile to cyanide is responsible for the greater sensitivity of male vs female mice: role of CYP2E1 and epoxide hydrolases

CYP2E1 expression in bone marrow and its intra-and interspecies variability: approaches for a more reliable extrapolation from one species to another in the risk …

Role of CYP2E1 and saturation kinetics in the bioactivation of thioacetamide: Effects of diet restriction and phenobarbital

Stable expression of human CYP2E1 in Chinese hamster cells: high sensitivity to N, N-dimethylnitrosamine in cytotoxicity testing

Immunological detection of CYP2E1 in fresh rat lymphocytes and its pretranslational induction by fasting

The induction of the human hepatic CYP2E1 gene by interleukin 4 is transcriptional and regulated by protein kinase C

Comparison of genetic polymorphisms of CYP2E1, ADH2, and ALDH2 genes involved in alcohol metabolism in Koreans and four other ethnic groups

Identification of inhibitory component in cinnamon—o-methoxycinnamaldehyde inhibits cyp1a2 and CYP2E1—

Hepatic and pulmonary microsomal benzene metabolism in CYP2E1 knockout mice

… in urea in conjunction with L-arginine metabolism in the liver leads to induction of cytochrome P450 2E1 (CYP2E1): The role of urea in CYP2E1 induction by acute …

Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N‐acetyltransferase in healthy human subjects

Detection of auto-antibodies against cytochrome P4502E1 (CYP2E1) in chronic hepatitis C

CYP2E1-catalyzed oxidation contributes to the sperm toxicity of 1-bromopropane in mice

Protective effects of loquat (Eriobotrya japonica) leaves against ethanol-induced toxicity in HepG2 cells transfected with CYP2E1

Transfected HepG2 cells for evaluation of catechin effects on alcohol-induced CYP2E1 cytotoxicity

Safrole-DNA adducts in human peripheral blood—an association with areca quid chewing and CYP2E1 polymorphisms

Increased bioaccumulation of urethane in CYP2E1-/-versus CYP2E1+/+ mice

Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity

Age-related changes in the protein and mRNA levels of CYP2E1 and CYP3A isoforms as well as in their hepatic activities in Wistar rats. What role for oxidative stress?

Functional CYP2E1 is required for substantial in vivo formation of 2, 5-hexanedione from n-hexane in the mouse

Metabolism of ethyl carbamate by pulmonary cytochrome P450 and carboxylesterase isozymes: involvement of CYP2E1 and hydrolase A

Genetic Repeat Polymorphism in the Regulating Region of CYP2E1: Frequency and Relationship With Enzymatic Activity in Alcoholics

… by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and Rat CYP2A3

Effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on toluene metabolism in humans

Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model

Investigation of bioactivation and toxicity of styrene in CYP2E1 transgenic cells

Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co‐expressing HCV core protein and CYP2E1

Acute ethanol pretreatment increases FAS-mediated liver injury in mice: role of oxidative stress and CYP2E1-dependent and-independent pathways

DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms significantly contribute to the risk of development of childhood …

Do Endogenous Volatile Organic Chemicals Measured in Breath Reflect and Maintain CYP2E1 Levelsin Vivo?

XRCC1 and CYP2E1 Polymorphisms as Susceptibility Factors of Plasma Mutant p53 Protein and Anti-p53 Antibody Expression in Vinyl Chloride …

Evidence of association of the CYP2E1 genetic polymorphism with micronuclei frequency in human peripheral blood

Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation)

CYP2E1 mRNA expression, genetic polymorphisms in peripheral blood lymphocytes and liver abnormalities in Chinese VCM-exposed workers

Role of CYP1A2 and CYP2E1 in the pentoxifylline ciprofloxacin drug interaction

Comparison of the susceptibility of wild-type and CYP2E1 knockout mice to the hepatotoxic and pneumotoxic effects of styrene and styrene oxide

High inducibility of mouse renal CYP2E1 gene by tobacco smoke and its possible effect on DNA single strand breaks

Effect of the CYP2E1 genotype on vinyl chloride monomer-induced liver fibrosis among polyvinyl chloride workers

Gene–environmental interactions between alcohol-drinking behavior and ALDH2 and CYP2E1 polymorphisms and their impact on micronuclei frequency in human …

Duration of cytochrome P-450 2E1 (CYP2E1) inhibition and estimation of functional CYP2E1 enzyme half-life after single-dose disulfiram administration in humans

Induction of CYP2E1 activity in liver transplant patients as measured by chlorzoxazone 6‐hydroxylation

Diallyl sulfide inhibition of CYP2E1 does not rescue diabetic rats from thioacetamide-induced mortality

Pulmonary bioactivation of trichloroethylene to chloral hydrate: relative contributions of CYP2E1, CYP2F, and CYP2B1

The 2006 bernard B. Brodie award lecture: CYP2E1

Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake

Effects of genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 on the urinary levels of 1-hydroxypyrene and 2-naphthol in aircraft maintenance workers

Genetic polymorphisms of CYP2E1 and GSTM1 in a Thai population

DLPC attenuates alcohol-induced cytotoxicity in HepG2 cells expressing CYP2E1

A comparison of substrate dynamics in human CYP2E1 and CYP2A6

S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice

Expression of CYP2E1 by human monocyte‐derived macrophages

CYP2E1 polymorphisms and gene–environment interactions in the risk of upper aerodigestive tract cancers among Indians

NAT2, CYP2C9, CYP2C19, and CYP2E1 genetic polymorphisms in anti-TB drug-induced maculopapular eruption

Role of CYP2E1 in the pathogenesis of alcoholic liver disease: modifications by cAMP and ubiquitin-proteasome pathway

Spectrophotometric analysis of human CYP2E1-catalyzed p-nitrophenol hydroxylation

Cervical cancer and CYP2E1 polymorphisms: implications for molecular epidemiology

Inactivation of hepatic CYP2E1 by an epoxide of diallyl sulfone

Insertion polymorphism of CYP2E1 and urinary N-methylformamide after N, N-dimethylformamide exposure in Japanese workers

Effect of exposure to benzo [a] pyrene on SODs, CYP1A1/1A2-and CYP2E1 immunopositive proteins in the blood clam Scapharca inaequivalvis

Ethanol-mediated transplacental induction of CYP2E1 in fetal rat liver

Breaking self-tolerance toward cytochrome P4502E1 (CYP2E1) in chronic hepatitis C: possible role for molecular mimicry

Cytochrome P450 2E1 (CYP2E1)-dependent production of a 37-kDa acetaldehyde–protein adduct in the rat liver

Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratios

Genotype and allele frequencies of polymorphic cytochromes P450 CYP1A2 and CYP2E1 in Mexicans

CYP1A1, CYP2E1, GSTM1, GSTT1, GSTP1, and TP53 polymorphisms: do they indicate susceptibility to chronic obstructive pulmonary disease and non-small-cell …

Effects of dietary fat composition on activities of the microsomal ethanol oxidizing system and ethanol‐inducible cytochrome P450 (CYP2E1) in the liver of rats …

Use of the CYP2E1 genotype and phenotype for the biological monitoring of occupational exposure to styrene

In vivo and in vitro characterization of chlorzoxazone metabolism and hepatic CYP2E1 levels in African Green monkeys: induction by chronic nicotine treatment

Proteasome inhibition potentiates CYP2E1‐mediated toxicity in HepG2 cells

Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure

Adenovirus-mediated expression of Cu/Zn-or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity

CYP2E1 G1532C, NQO1 Pro187Ser, and CYP1B1 Val432Leu polymorphisms are not associated with risk of squamous cell carcinoma of the head and neck

CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling

Malotilate, a hepatoprotectant, suppresses CYP2E1 expression in rats

Role of mouse CYP2E1 in the O-hydroxylation of p-nitrophenol: comparison of activities in hepatic microsomes from CYP2E1 (-/-) and wild-type mice

Pulsatile blood alcohol and CYP2E1 induction during chronic alcohol infusions in rats

… dehydrogenase 2, cytochrome p450 2E1 for liver cancer risk in HCV antibody-positive japanese patients and the variations of CYP2E1 mRNA expression levels in the …

Use of CYP2E1‐transfected human liver cell lines in elucidating the actions of ethanol

In vivo CYP2E1 phenotyping as a new potential biomarker of occupational and experimental exposure to benzene

Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression

Genetic polymorphisms of the CYP2E1 gene do not contribute to oral cancer susceptibility in south Indians

Phenotype distribution and gender-related differences of CYP2E1 activity in a Chinese population

Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1

Influence of genetic admixture on polymorphisms of drug‐metabolizing enzymes: Analyses of mutations on NAT2 and CYP2E1 genes in a mixed Hispanic …

Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells

Association Studies of Polymorphisms of CYP2E1 Gene in Alcoholics with Cirrhosis, Antisocial Personality, and Normal Controls

Transcriptional and posttranscriptional regulation of CYP2E1, an N-nitrosodimethylamine demethylase.

Association of CYP2E1, GST and mEH genetic polymorphisms with urinary acrylamide metabolites in workers exposed to acrylamide

Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity

Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: Role of CYP2E1 and TNF-α and activation of JNK and P38 MAP kinase

Role of CYP2E1 in deramciclane metabolism

S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury

The influence of genetic polymorphism of CYP2E1 on the development of alcohol liver cirrhosis

p53 mutation spectrum in relation to GSTM1, CYP1A1 and CYP2E1 in surgically treated patients with non-small cell lung cancer.

Evidence for a tissue-specific induction of cutaneous CYP2E1 by dexamethasone

Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes

Genetic Polymorphisms of CYP2E1 and Risk of Colorectal Adenomas in the Self Defense Forces Health Study

CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls

The effect of lycopene on the total cytochrome P450, CYP1A2 and CYP2E1

Chlorzoxazone metabolism by winter flounder liver microsomes: evidence for existence of a CYP2E1-like isoform in teleosts

Role of CYP2E1 in the mouse model of MPTP toxicity

Genetic polymorphism of CYP2E1 and digestive tract alcohol damage among Polish individuals

CYP2E1 genotyping in renal cell/urothelial cancer patients in comparison with control populations.

Genetic polymorphisms of CYP2E1, GSTT1, GSTP1, GSTM1, ALDH2, and ODC and the risk of advanced precancerous gastric lesions in a Chinese population

Transgenic plants of Petunia hybrida harboring the CYP2E1 gene efficiently remove benzene and toluene pollutants and improve resistance to formaldehyde

Induction of CYP2B and CYP2E1 in precision-cut rat liver slices cultured in defined medium

Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-κB …

Mammalian cytochrome CYP2E1 triggered differential gene regulation in response to trichloroethylene (TCE) in a transgenic poplar

Short-term treatment with alcohols causes hepatic steatosis and enhances acetaminophen hepatotoxicity in CYP2E1 (-/-) mice

Phosphorylation of cytochrome P4502E1 (CYP2E1) by calmodulin dependent protein kinase protein kinase C and cAMP dependent protein kinase

PI3K inhibitors reverse the suppressive actions of insulin on CYP2E1 expression by activating stress-response pathways in primary rat hepatocytes

In vitro metabolism of styrene to styrene oxide in liver and lung of CYP2E1 knockout mice

Dietary lipids affect human ethanol-inducible CYP2E1 gene expression in vivo in mononuclear cells

Independent and combined effects of ethanol self-administration and nicotine treatment on hepatic CYP2E1 in African green monkeys

… of human prenatal biosynthesis of all-trans-retinoic acid by ethanol, ethanol metabolites, and products of lipid peroxidation reactions: a possible role for CYP2E1

Gene Structure and Multiple Regulations of the Ethanol-Inducible Cytochrome P45O2E1 (CYP2E1) Subfamily

Role of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells

Panax vietnamensis protects mice against carbon tetrachloride-induced hepatotoxicity without any modification of CYP2E1 gene expression

Study on the association between genetic polymorphism of CYP2E1, GSTM1 and susceptibility of lung cancer

A multiplex-PCR/RFLP procedure for simultaneous CYP2E1, mEH and GSTM1 genotyping

Lycopene attenuates arachidonic acid toxicity in HepG2 cells overexpressing CYP2E1

APOE and CYP2E1 polymorphisms, alcohol consumption, and Parkinson’s disease in a Japanese population

Epoxide formation from diallyl sulfone is associated with CYP2E1 inactivation in murine and human lungs

D2-receptor-linked signaling pathways regulate the expression of hepatic CYP2E1

Metabolic activation of o-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1

Expression and activity of CYP2E1 in circulating lymphocytes are not altered in diabetic individuals

Modification effects of GSTM1, GSTT1 and CYP2E1 polymorphisms on associations between raw salted food and incomplete intestinal metaplasia in a high‐risk …

Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques

Depression of glutathione content, elevation of CYP2E1-dependent activation, and the principal determinant of the fasting-mediated enhancement of 1, 3-dichloro-2 …

Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1, 3‐dimethyluric …

Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in …

Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells

No significant expression of CYP2E1 in rat liver stellate cells

CYP2E1 and clinical features in alcoholics

Comparison of chlorzoxazone one-sample methods to estimate CYP2E1 activity in humans

Acetaminophen alters microsomal ryanodine Ca2+ channel in HepG2 cells overexpressing CYP2E1

No Association between Polymorphisms in CYP2E1, GSTM1, NAT1, NAT2 and the Risk of Gastric Adenocarcinoma in the European Prospective Investigation into …

The effect of isoniazid containing regimen on CYP2E1 during antituberculosis therapy.

A Haplotype Analysis of CYP2E1 Polymorphisms in Relation to Alcoholic Phenotypes in Mexican Americans

A reaction network model for CYP2E1-mediated metabolism of toxicant mixtures

Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1

Cytochrome b5 reductase and cytochrome b5 support the CYP2E1-mediated activation of nitrosamines in a recombinant Ames test

Overexpression of CYP2E1 enhances sensitivity of hepG2 cells to fas-mediated cytotoxicity

INFLUENCE OF GENETIC ADMIXTURE ON POLYMORPHISMS OF ALCOHOL-METABOLIZING ENZYMES: ANALYSES OF MUTATIONS ON THE CYP2E1, ADH2, ADH3 AND …

Liver nuclear and microsomal CYP2E1-mediated metabolism of xenobiotics in rats chronically drinking an alcohol-containing liquid diet

Effect of CYP2E1 induction by ethanol on the immunotoxicity and genotoxicity of extended low-level benzene exposure

Role of nitric oxide and nuclear factor-κB in the CYP2E1 potentiation of tumor necrosis factor α hepatotoxicity in mice

Identification of sequences responsible for intracellular targeting and membrane binding of rat CYP2E1 in yeast

Suppression of cytochrome P450 2E1 promoter activity by interferon-γ and loss of response due to the-71G> T nucleotide polymorphism of the CYP2E1* 7B allele

Identification and functional analysis of a novel human CYP2E1 far upstream enhancer

Rifampicin suppresses hepatic CYP2E1 expression and minimizes DNA injury caused by carbon tetrachloride in perivenular hepatocytes of mice

Inhibition of CYP2E1 activity does not abolish pulsatile urine alcohol concentrations during chronic alcohol infusions

Molecular cloning and sequence analysis of hamster CYP2E1

Relationship between genetic polymorphism of CYP2E1 and ALDH2, and possible susceptibility to alcoholism

… mechanism of Wu-Zi-Yan-Zong-Wan, a traditional Chinese herbal formula, against alcohol-induced oxidative damage in CYP2E1 cDNA-transfected HepG2 (E47) …

… overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1

Effects of steady-state lasofoxifene on CYP2D6-and CYP2E1-mediated metabolism

[12] Chlorzoxazone: An in vitro and in vivo substrate probe for liver CYP2E1

CYP2E1-dependent bioactivation of 1, 1-dichloroethylene in murine lung: formation of reactive intermediates and glutathione conjugates

Modulation of mouse P450 isoforms CYP1A2, CYP2B10, CYP2E1, and CYP3A by the environmental chemicals mirex, 2, 2-bis (p-chlorophenyl)-1, 1-dichloroethylene …

Lack of cytochrome P450 2E1 (CYP2E1) induction in the rat liver by starvation without coprophagy

Influence of GSTs, CYP2E1 and mEH polymorphisms on 1, 3-butadiene-induced micronucleus frequency in Chinese workers

Influence of GSTT1, mEH, CYP2E1 and RAD51 polymorphisms on diepoxybutane-induced SCE frequency in cultured human lymphocytes

Tightly regulated and inducible expression of rabbit CYP2E1 using a tetracycline-controlled expression system

Striking LD50 variation associated with fluctuations of CYP2E1-positive cells in hepatic lobule during chronic CCl4 exposure in mice

Expression of cytochrome P450 enzymes CYP1A1, CYP1B1, CYP2E1 and CYP4B1 in cultured transitional cells from specimens of the human urinary tract and from …

Isozyme-selective metabolism of ethyl carbamate by cytochrome P450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes in murine liver microsomes

… of the accumulation of acetaldehyde from ethanol in human prenatal cephalic tissues: evaluation of the relative contributions of CYP2E1, alcohol dehydrogenase, and …

CYP2E1 and CYP3A1/2 gene expression is not associated with the ursodeoxycholate effect on ethanol-induced lipoperoxidation

CYP2E1 inhibition enhances mallory body formation

XRCC1, CYP2E1 and ALDH2 genetic polymorphisms and sister chromatid exchange frequency alterations amongst vinyl chloride monomer-exposed polyvinyl …

Cytochrome b5 coexpression increases the CYP2E1-dependent mutagenicity of dialkylnitrosamines in methyltransferase-deficient strains of Salmonella typhimurium

Effect of disulfiram‐mediated CYP2E1 inhibition on the disposition of vesnarinone

Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity

CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells

Induction of brain CYP2E1 changes the effects of ethanol on dopamine release in nucleus accumbens shell

The role of phosphatidylinositol 3-kinase, Src kinase, and protein kinase A signaling pathways in insulin and glucagon regulation of CYP2E1 expression

Voglibose potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen by inducing CYP2E1 in rats

Administration of the tris salt of α-tocopheryl hemisuccinate inactivates CYP2E1, enhances microsomal α-tocopherol levels and protects against carbon tetrachloride …

Influence of selected inhibitors on the metabolism of the styrene metabolite 4-vinylphenol in wild-type and CYP2E1 knockout mice

Lack of common mutation in the alfa-subunit of the mitochondrial trifunctional protein and the polymorphism of CYP2E1 in three Japanese women with acute fatty liver …

Induction of CYP1A1 and CYP2E1 in rat liver by histamine: binding and kinetic studies

Cytochrome P4502E1 (CYP2E1) Genetic Polymorphisms in a Lebanese Population: Frequency Distribution and Association with Morbid Diseases

CYP1A1 and CYP2E1 polymorphism frequencies in a large Brazilian population

THE EFFECTS OF THE ALDH2*1/2, CYP2E1 C1/C2 AND C/D GENOTYPES ON BLOOD ETHANOL ELIMINATION

Noninvolvement of CYP2E1 in the (ω-1)-hydroxylation of fatty acids in rat kidney microsomes

Effect of total alkaloids of Rubus alceaefolius poiron on gene expressions of CYP2E1 and CYP3A1 in rats with acute liver injury

Watercress has no importance for the elimination of ethanol by CYP2E1 inhibition

Inhibition of rat hepatic CYP2E1 by quinacrine: molecular modeling investigation and effects on 4-(methyl nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced …

Undernutrition during hyperoxic exposure induces CYP2E1 in rat liver

Transcriptional activity of the tandem repeat polymorphism in the 5′‐flanking region of the human CYP2E1 gene

Trifluoroacetylated adducts in spermatozoa, testes, liver and plasma and CYP2E1 induction in rats after subchronic inhalatory exposure to halothane

A polymorphism in the 5′-flanking region of the CYP2E1 gene and elevated lung adenocarcinoma risk in a Japanese population

Polymorphisms of the CYP1A1, CYP2E1 and XRCC1 genes and cancer risk in a Southern Italian population: a case–control study

CYP2E1 level in rat liver injured by the interaction between carbon tetrachloride and chloroform

Serum autoantibodies against cytochrome P450 2E1 (CYP2E1) predict severity of necroinflammation of recurrent hepatitis C

Association of CYP2E1 of PON2311 polymorphisms in neonates with preterm

Role of CYP2E1 in ketone-stimulated insulin release in pancreatic B-cells

Relative roles of CYP2E1 and CYP1A2 in mouse uroporphyria caused by acetone

Extrahepatic metabolism by CYP2E1 in PBPK modeling of lipophilic volatile organic chemicals: impacts on metabolic parameter estimation and prediction of dose …

Use of Duplex PCR-CTPP Methods for CYP2E1 RsaI/IL-2 T-330G and IL-1B C-31T/TNF-A T-1031C Polymorphisms

Examination of a CYP2E1 repeat polymorphism in a monkey model of alcohol abuse

CYP2E1 overexpression up-regulates both non-specific δ-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1

Metabolism and toxicity of the styrene metabolite 4-vinylphenol in CYP2E1 knockout mice

Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells

Urinary excretion of 6‐hydroxychlorzoxazone as an index of CYP2E1 activity

Cloning and expression of rat CYP2E1 in Saccharomyces cerevisiae: Detection of genotoxicity of N‐alkylformamides

Role of the Genetic Polymorphisms in the 5′‐Flanking Region for Transcriptional Regulation of the Human CYP2E1 Gene

Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and …

Conformational anti‐cytochrome P4502E1 (CYP2E1) auto‐antibodies contribute to necro‐inflammatory injury in chronic hepatitis C

Relation of GSTP1 and CYP2E1 polymorphisms with susceptibility to acute leukemia

Decreased CYP2E1 mRNA expression in human leucocytes in patients with fibrotic and inflammatory lung diseases

ALDH2 and CYP2E1 genotypes, urinary acetaldehyde excretion and the health consequences in moderate alcohol consumers

The NH2-terminal region of rabbit CYP2E1 is not essential for interaction with NADPH-cytochrome P450 reductase

Effect of high‐dose aspirin on CYP2E1 activity in healthy subjects measured using chlorzoxazone as a probe

Genetic variation in the temperature dependence of liver microsomal CYP2E1 activity, within and between species of the viviparous fish Poeciliopsis

Insertional polymorphism of the CYP2E1 gene in infiltrative pulmonary tuberculosis in populations of Bashkortostan Republic

Cryopreserved porcine hepatocytes: expression and induction of cytochrome P450, isoform CYP2E1

Comparison of levels of cytochromes P‐450, CYP1A2, CYP2E1, and their related monooxygenase activities in human surgical liver samples

Modulation of ethanol-mediated CYP2E1 induction by clofibrate and L-carnitine in rat liver

The effect of endotoxin on hepatocyte nuclear factor 1 nuclear protein binding: potential implications on CYP2E1 expression in the rat

Effect of CYP2E1 polymorphism on DNA stability and lung cancer susceptibility

Area Under the Plasma Concentration–Time Curve of Inorganic Fluoride Following Sevoflurane Anesthesia Correlates with CYP2E1 mRNA Level in Mononuclear …

Identification of a 16-nucleotide sequence that mediates post-transcriptional regulation of rat CYP2E1 by insulin

Fetal and maternal CYP2E1 genotypes and the risk of nonsyndromic oral clefts

Bioactivation of 1, 1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes

Exacerbation of benzene pneumotoxicity in connexin 32 knockout mice: enhanced proliferation of CYP2E1-immunoreactive alveolar epithelial cells

Comparison of cytochrome P4502E1 (CYP2E1) activity and hepatic and lymphocyte mRNA expression in patients with chronic hepatitis C

IL-4-mediated transcriptional regulation of human CYP2E1 by two independent signaling pathways

Phorbol ester induces CYP2E1 in astrocytes, through a protein kinase C‐and tyrosine kinase‐dependent mechanism

Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity

Polymorphism of the 5′‐Flanking Region of the CYP2E1 Gene: An Association Study With Alcoholism

Activity of immobilised rat hepatic microsomal CYP2E1 using alumina membrane as a support

Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1

Isolation of the mouse cytochrome P450J (CYP2E1) cDNA and its reciprocal testosterone regulation in kidney and liver

Hepatotoxicity Mediated by Pyrazole (CYP2E1) Plus TNF-α Treatment Occurs in jnk2−/− but not in jnk1−/− Mice

A comparison of the inhibitory effects of four volatile anaesthetics on the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits

Contribution of the ALDH2 and CYP2E1 genes to flushing response and drinking patterns in Japanese healthy volunteers

Assessment of frequencies of lifestyle factors and polymorphisms of drug-metabolizing enzymes (NAT2, CYP2E1) in human hepatocellular carcinoma (HCC) patients …

Upregulation of CYP2E1 and cyp3a activities in histamine-deficient histidine decarboxylase gene targeted mice

Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1, 3-dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat

Comparison of the polymorphic regions of the cytochrome P450 CYP2E1 gene of humans and patas and cynomolgus monkeys

Cytochrome p-450-mediated differential oxidative modification of proteins: albumin, apolipoprotein E, and CYP2E1 as targets

Activation of alkylhydrazines to free radical intermediates by ethanol-inducible cytochrome P-4502E1 (CYP2E1)

Insertion Polymorphism of the CYP2E1 gene in patients with infiltrative pulmonary tuberculosis from Bashkortostan

Dichloroacetic acid treatment increases hepatic CYP2E1 in male and female rats

Altered ethylbenzene-mediated hepatic CYP2E1 expression in growth hormone-deficient dwarf rats

Polymorphisms of the cytochrome P450 (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) genes in cystic fibrosis and chronic respiratory disease

… , Scrophularia ningpoensis, Asparagus cochinchinensis and Ophiopogon japonicas on contents of CYP450 and activities of CYP3A, CYP2E1 and CYP1A2 in rat

Genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fishes Poeciliopsis occidentalis and Poeciliopsis lucida

Diminished CYP2E1 expression and formation of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1, 1-dichloroethylene epoxide, in murine lung tumors

Effect of 1-aminobenzotriazole on the in vitro metabolism and single-dose pharmacokinetics of chlorzoxazone, a selective CYP2E1 substrate in Wistar rats

The genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fish Poeciliopsis

Bioactivation of 1, 1-dichloroethylene by CYP2E1 and CYP2F2 in murine lung

Effects of chlorinated aliphatic hydrocarbons on the fidelity of cell division in human CYP2E1 expressing cells

Abnormal liver function associated with polymorphism of GSTT1, GSTM1 and CYP2E1 in workers exposed to N, N-dimethylformamide

CYP2E1–Biochemical and Toxicological Aspects and Role in Alcohol-Induced Liver Injury

Case-control study of the polymorphisms of CYP2E1-RsaⅠ and STT1 genes and susceptibility to pancreatic cancer

Genetic polymorphisms of alcohol inducible CYP2E1 in Turkish population

Expression of human CYP2E1 in insect cells using bac-to-bac expression system

A Case-control study on effects of genetic polymorphisms of GSTM1, GSTT1, CYP1A1 and CYP2E1 on risk of lung cancer

Glucose inhibition of the induction of CYP2E1 mRNA expression by ethanol in FGC-4 cells

Effect of methacrylonitrile on cytochrome P-450 2E1 (CYP2E1) expression in male F344 rats

… of liver microsomal 7-ethoxycoumarin O-deethylation and chlorzoxazone 6-hydroxylation activities in Japanese and Caucasian subjects genotyped for CYP2E1 gene

No linkage of the cytochrome P-450IIE1 (CYP2E1) C1/C2 polymorphism to schizophrenia

Antibodies against CYP2E1 after exposure to 1, 1, 1-trifluoroethane and 1, 1, 1, 2-tetrafluoroethane

Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5′-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR)

Immunohistochemical Detection of CYP2E1 and 2-S-Glutathionyl Acetate in Murine Lung Tumors: Diminished Formation of Reactive Intermediates of 1,1 …

CYP2E1 genotypes and serum LAP in Japanese alcoholics

Genetic polymorphisms of CYP2E1

Non-positive autoimmune responses against CYP2E1 in refrigeration mechanics exposed to halogenated hydrocarbons

Development of a non-high pressure liquid chromatography assay to determine [14C] chlorzoxazone 6-hydroxylase (CYP2E1) activity in human liver microsomes

The colorectal cancer risk of meat intake, smoking, and CYP2E1 polymorphisms: the comparison of colorectal cancer patients with controls

Genetic Polymorphism of Alcohol Metabolizing Enzymes, CYP2E1

Relationship between CYP2E1 polymorphism and increase of ALT activity during therapy of patients with pulmonary tuberculosis

Halothane inhalation inhibits the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits

Analysis of CYP2E1 and GSTM1 polymorphisms for the determination of genetic susceptibility to Korean patients with colon cancer

Inactivation of cytochrome P-450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes by vinyl carbamate in murine pulmonary microsomes

Antibiotic furazolidone induces CYP1A but not CYP2E1 subfamily in rat liver

Effect of starvation and acetone on the enzyme systems of biotransformation and toxicity of xenobiotics–CYP2E1 substrates in rats

Comparative analysis of binding affinities between styrene and mammalian CYP2E1 by bioinformatics approaches

Study of the fragmentation mechanism of protonated 6-hydroxychlorzoxazone: application in simultaneous analysis of CYP2E1 activity with major human cytochrome …

Gene CYP2E1 expression in mouse liver cells exposed to low-dose radiation

Interaction of polymorphisms of CYP2E1 and environmental risk factors in gastric cancer

Effect of Genetic Polymorphisms of CYP2E1 and ALDH2 on the Relationship between the Levels of Urinary 8-Hydroxydeoxyguanosine and t, t-Muconic Acid

Trimethadione N-demethylation by rat liver CYP2E1 in vitro.

Correlation analyses of ALDH2 and CYP2E1 genetic polymorphism with personality

Variations in expression of CYP2E1 and COUP-TF1 proteins between Large White and Duroc cross-breeds

GYKI-47261, a new AMPA [2-amino-3-(3-hydroxymethylisoxazole-4-yl) propionic acid] antagonist, is a CYP2E1 inducer

Research on the relationship between ALDH2 and CYP2E1 gene polymorphism and alcoholic liver disease in Han people

Differential expression of cytochrome P4502E1 (CYP2E1) in Morris hepatomas and livers of tumor bearing rats.

A novel lipopolysaccharide‐modulated Jun binding repressor in intron 2 of CYP2E1

Association analysis of alcohol metabolizing enzymes ADH1B, ADH7, CYP2E1 gene polymorphism with risk for coronary atherosclerosis

Identification of polymorphisms in CYP2E1 gene and association analysis among chronic HBV patients

Increase expression of CYP2E1 mRNA after methamphetamine administration in rats

The role of CYP2E1 in the protection of garlic oil’s from n-hexane-induced neurotoxicity

Pulmonary bioactivation of 1, 1-dichloroethylene is associated with CYP2E1 levels in A/J, CD-1, and C57BL/6 mice

Ethanol-induction of cytochrome P450 2A5: permissive role for CYP2E1

Characterization of a dietary ethanol protocol for CYP2E1 induction in the CD-1 mouse without evident hepatic toxicity or genotoxicity

A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1

Cytochemical Localization of the Acetone-lnducible Cytochrome P-450 Isoform, CYP2E1 in Murine Colonic Epithelium

A study for regulation of ethanol-inducible P450 (CYP2E1) on CCl4-induced hepatic damage

Associations of Rsa I polymorphism at the 5’flanking region of CYP2E1 and PON2 148 polymorphism in neonates with preterm delivery

Effect of sulfur dioxide inhalation on CYP2B1/2 and CYP2E1 in rat liver and lung

Genetic polymorphism of human CYP2E1: new allels detected in exons and exon-intron junctions

Relationship between alcoholism and CYP2E1 genotypes

A case control study on the impact of CYP2E1 and GST-M1 polymorphisms on the risk of lung cancer

Preliminary effects of alcohol and Curcuma longa upon CYP2E1 and hematotoxicity in benzene-induced mice

Association of genetic polymorphisms of aldehyde dehydrogenase II and CYP2E1 and clinical characteristics of patients with alcohol dependence

Downregulation of the CYP2E1 ameliorates oxidative stress and apoptosis

Interaction between genetic polymorphisms of CYP2E1 & NAT1 and smoking in lung cancer development (Preliminary report)

Human CYP2E1 developmental expression: a role in fetal and pediatric susceptibility to toxicants?

Effects of environmental carcinogens and genetic polymorphisms of CYP2E1 and NAT2 on gastric carcinogenesis

Effects of Purified Glycerol from Biodiesel on Cyp1a1 and CYP2E1 Expressions in CBA/CA Mice

Fast CYP2E1 genotyping using automated fluorescent detection.

Association of CYP2E1, NQO1 and GST genetic polymorphisms with risk of acute lymphoblastic leukemia in turkish children

Ruthenium red protects HepG2 cells overexpressing CYP2E1 against acetaminophen cytotoxicity

CYP2E1 competes with CYP2B4 for limited NADPH‐Cytochrome P450 Reductase

Expression and regulation of cytochrome P450 CYP2E1 in the minipig

Effect of TFHL on expression of CYP2E1 in liver tissue of rats with NASH.

Effects of ginsenoside Rd and Panax ginseng extract on Cyp1a, Cyp2b, Cyp2c, CYP2E1, and Cyp3a activities in C57BL/6JNarl mice

The research on the relationship between CD44, CYP2E1 genetic polymorphisms and esophageal cancer

Action-mechanisms of Genetic Polymorphism in the CYP2E1 on Susceptibility to Polycyclic Aromatic Hydrocarbons

CYP1A1, CYP2E1 and gastric cancer risk in a high-incidence Colombian population

Ontogeny of Rat CYP2E1 and CYP1A2: A Characterization and

Effects of mitomycin (MMC) and {gamma}-ray irradiation on cytochrome p450 content and activities of CYP2B1 and CYP2E1 in rats

The modeling of interactions of the CYP2E1 isoform of human cytochrome P450 with substrates

Identification of CYP2E1-dependent genes involved in carbon tetrachloride-induced hepatotoxicity

Evidence for the Existence of Two Human CYP2E1 cDNAs Using Different Polyadenylation Signals

Functional polymorphism of CYP2E1 gene and alcohol use disorders in a Tibetan population.

The ethanol elimination pharmacokinetics–the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism

Differential expression profile of cytochrome p450 2E1 (CYP2E1) related genes associated with carbon tetrachloride-induced hepatotoxicity

Effect of total saikosaponins on the intestinal first-pass effect and liver Cyp3a, CYP2E1

Relationship between gene polymorphism of CYP2E1, CYP1A1, IL-4 and medicamentosa-like dermatitis induced by trichloroethylene

High dose lycopene supplementation increases hepatic CYP2E1 protein and TNF‐α expression in alcohol fed rats

The ethanol elimination pharmacokinetics–the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism

Silibinin inhibits CYP2E1‐dependent ethanol metabolism, oxidative stress and cell proliferation in a rat model of hepatocellular carcinoma (HCC)

Opposite effects of isoniazid and fasting on the expression of CYP2E1 protein and mRNA in house musk shrew (Suncus murinus)

Computational docking studies of nitroanisoles and nitrophenols with CYP2E1

ALDH and CYP2E1 Single Nucleotide Polymorphism Distribution in Korean

Role of CYP2E1 in Hepatocarcinogenesis and Hepatotoxicity

An investigation of CYP2E1 phenotype determination utilizing modeling and simulation studies

Formation of Multiple CYP2E1 Complexes Affects Activity

Regulation of CYP2E1 and Tissue Protection Effect of CYP2E1 Inhibitor

Mapping of pig CYP2E1 to SSC14

ALDH and CYP2E1 Single Nucleotide Polymorphism Distribution in Korean

CYP2E1 mutation associated with increased chlorzoxazone (CZ) metabolic ability

Alcohol, Nicotine and Genetic Variation Influence CYP2E1

Different CYP2E1 genotypes and alcoholic liver disease.

Establishment and toxicological application of a cell line expressing human CYP2E1

The Toxicological Mechanism Of Styrene In CYP2E1 Transgenic Cells

Effect of CYP2E1 Ras I genotypes on CYP2E1 enzyme activity and DNA damage induced by phenol in immortalized human lymphocytes

Effects of environmental factors on extrahepatic CYP2E1 gene expression in mice

Molecular Evidence for the Presence of CYP2E1 Retropseudogene in Human Genome

Role Of Mouse CYP2E1 In The O-Hydroxylation Of P-Nitrophenol: Comparison Of Activities In CYP2E1 (-/-) And Wildtype Mice

Structure-functional characterization of cytochrome P4502E1 (CYP2E1)

Establishment of model with exogenous human CYP2E1 expression and inducement of substrates

Chlorzoxazone as a Single Sample Probe of Hepatic CYP2E1 Activity

A relationship between genetic polymorphisms of CYP2E1 and susceptibility of acute leukemia in Gansu population

Application of a map Bayesian method for CYP2E1 phenotyping

Role of CYP2E1 Immunoglobulin G4

Individual variability of CYP2E1 xenobiotic oxidation in human liver

The genotype of CYP2E1 and liver-derived serum enzymes

A-71G> T Nucleotide Substitution uncouples IFN-[gamma]-dependent Suppression of CYP2E1 mRNA

Pathogenesis of nonalcoholic steatohohepatitis [sic]: the role of CYP2E1

Hormonal regulation of CYP2E1 and CYP2C11 in rat liver and kidney

Inhibition of Ethanol-induced CYP2E1 by Curcuma longa L. Extract

Immunological detection of CYP2E1 in the fresh lymphocytes

THE EFFECT OF COPROPHAGY ON THE EXPRESSION OF HEPATIC CYP2E1 DURING STARVATION

Effects of Danshen and Its Active Components on Rat CYP2E1 Expression and Metabolism of Model CYP2E1 Probe Substrate

Construction of CYP2E1 recombinant adenovirus vector and its anti-tumor effects

CYP2E1-DEPENDENT BIOACTIVATION OF 191

Role Of Cytochrome P450 2E1 (CYP2E1) In Trichloroethylene (TCE) Metabolism And Disposition: Comparative Studies Using CYP2E1-/-And Wild-Type Mice

The role of CYP2E1 and CYP4A in the development of non-alcoholic steatohepatitis

CYP2E1 VNTR polymorphisms and hepatocarcinoma: a gender-specific correlation

Substrate inhibition of CYP2E1 activity is primarily determined by lipophilicity

Expression of CYP2E1 gene in liver tissue in patients with hepatic cirrhosis and obstuctive jaundice

Study on the association between CYP2E1 enzymes and susceptibility of alcoholic liver disease

An investigation of the induction of hepatic CYP2E1 by low doses of nicotine in the rat.

The Effects of CYP2E1 and CYP2C19 Polymorphisms on the Susceptibility for Gastric Cancer

Time-coursed Changes of CYP2E1 Protein in Acute Liver Injury by a Single CCI₄ Administration in SD Rats

Search for possible changes in murine gene CYP2E1 structural region under exposure to ionizing radiation

MAPPING CONFORMATIONAL CYP2E1 EPITOPES RECOGNISED BY AUTO-ANTIBODIES IN HALOTHANE HEPATITIS AND ALCOHOLIC LIVER DISEASE

The Genetic Polymorphism of CYP2E1 in a Korean Healthy Subjects and Hepatocellular Carcinoma Patients

Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratio

CYP2E1 Genetic Polymorphism relating to Styrene Metabolism of Korean Workers

Pharmacokinetics of drug interactions due to ligand stabilization of CYP2E1

Determination of the activity of human hepatic cytochromes P450 CYP2C8/9, CYP2E1

ALLELIC VARIANTS OF CYP2E1 GENE IN HEPATOCARCINOMA PATIENTS AND IN HEPATIC TUMOR CELL LINES

e0048 CYP2E1 increases oxidative stress and induces apoptosis of cardio myocytes in transgenic mice

Catalytic activity and quantitation of CYP2E1 in human embryonic and fetal brain tissues

Various Fatty Acids Induce Cell Damages Differently in CYP2E1-transduced HepG2 Cells, E47 Cells, Compared to C34 Cells

Polymorphisms of ADH2, ALDH2 and CYP2E1 in huichol and Mestizo subjects from western México in comparison with other populations of the world

Cloning and sequence analysis of human embryonic nasopharyngeal epithelial CYP2E1 cDNA

The influence of Jiuganning decoction on the content of CYP2E1 and cytokine IL-6, TNF in rats models of alcoholic hepatic injury

Identification of a critical CYP2E1 epitope in patients with drug-induced liver injury from anesthetics (93.16)

Experimental study on effect of Erchen decoction and Taohongsiwu decoction on CYP2E1 activities in non-alcoholic fatty liver rats

Use of Cytochrome P450 2E1 (CYP2E1) Knockout Transgenic Mouse Model to Study the Role of CYP2E1 in Carbon Tetrachloride-and Alcohol-mediated …

The role of CYP2A6 and CYP2E1 in the metabolism of 3-methylindole in porcine hepatocytes.

Role of CYP2E1 in Impaired Nitric Oxide Synthase (NOS)‐Dependent Cerebral Vasodilation During Chronic Alcohol Consumption

Increased citrate levels in non-alcoholic steatohepatitis: effect on CYP2E1

The Role of CYP2E1 IgG4 Subclass Autoantibodies in the Development of Anesthetic Sensitization

Cutaneous CYP2E1 induction after topical treatment by dexamethasone, ethanol and salicylic acid in mouse.

Meta-analysis on relationship between polymorphisms of CYP2E1 gene and susceptibility to antituberculosis drug-induced liver injury

Modulation of Murine CYP2E1 Activity by Disulfiram on Trichloroethylene-Induced Neurotoxicity A Pilot Study

Chlormethiazole, an inhibitor of CYP2E1, prevented chemical carcinogen-initiated and alcohol-promoted hepatic carcinongenesis in rats.

Single Nucleotide Polymorphisms in the Non-coding region of CYP2E1 among Koreans

The Effects of Poly IC and Human Interferon ɑ on Rat Hepatic Cyp4a1 and CYP2E1

Inhibition of Urethane-Induced Carcinogenicity in CYP2E1-/-Vs. CYP2E1+/+ Mice

Polymorphism of CYP2E1 gene and the risk of lung cancer among African-Americans and Caucasians in Los Angeles County (California).

Association of the blood biochemical index with CYP2E1 5’flanking region Rsa I/Pst I gene polymorphism and alcohol consumption habit in Southern Taiwan …

The Effects of Chungganhaeju-tang(Qingganjiejiu-tang) on Alcohol induced Cytotoxicity in CYP2E1-transfected HepG2 cells.

Investigation of indazole unbinding pathways in CYP2E1 by molecular dynamics simulations

CYP2E1: Mechanism of induction by isoniazid and role in acetaminophen oxidation

Analyses of Mutation Frequency on the CYP2E1, ADH2, and ALDH2 Genes among Five Ethnic Groups

Molecular Regulation of Ethanol-inducible P450 (CYP2E1) in Acute CCI₄Treatment

CYP2E1-dependent bioactivation of 1, 1-dichloroethylene to reactive intermediates in murine and human lung and liver microsomes.

CYP2E1 Mediates Ethanol-Induced DNA Damage And TNF Release In Bronchial Epithelial Cells

Oral clefts, maternal exposure to solvents and CYP2E1 polymorphism

Effect of γ-irradiation and mitomycin C (MMC) on CYP2B1 and CYP2E1 activities in rat hepatic microsomes in vitro

The Effects of CYP2E1 on Hepatic Gene Expression in 129/Sv-CYP2E1^ tm1Gonz/J and 129S1/SvImJ Mice Exposed to Hydrazine

Variable Number of Tandem Repeats (VNTR) gene polymorphism of CYP2E1 in patients with pancreatic adenocarcinoma

THE EFFECT OF ETHANOL ON COUMARIN METABOLISM AND CYTOTOXICITY IN TRANSFECTED CULTURES OF HEPG2 CELLS WITH CYP2E1 EXPRESSION.

Cytochrome P450 2E1 (CYP2E1) Induction By Pyridazine Produces Qualitative And Quantitative Changes In The Metabolism Of Trichloroethylene To Potentially …

Inhibition of B12‐dependent methionine synthase activity in HepG2 cells over‐expressing CYP2E1

Overexpression of CYP2E1 Increases Sensitivity of HepG2 Cells to Isoniazid-Induced Cytotoxicity

Relation between genetic polymorphisms of ADH, CYP2E1, GSTP1 and their expression in Caucasian lung tissue

Detection of autoantibodies against cytochrome P450 2E1 (CYP2E1) in patients with recurrent hepatitis C

Lack of correlation between lymphocytic mrna expression and activity of CYP3A4 and CYP2E1 In‐vivo in alcoholics and non‐alcoholics

RELATIONSHIPS BETWEEN GENETIC POLYMORPHISMS IN CYP2D6 AND CYP2E1 GENES AND LIVER MICROSOMAL DRUG OXIDATION ACTIVITIES

NADPH: CYTOCHROME P450 REDUCTASES OF VARIOUS SPECIES CAN BE USED IN SYSTEMS RECONSTITUTING DRUG-METABOLIZING CYP2E1 …

Single nucleotide polymorphisms and variable number of tandem repeat polymorphism of CYP2E1 in Koreans

Strain-related Differences in CYP2E1 Levels are Associated with Differential Bioactivation of 1, 1-dichloroethylene in Murine Lung and Liver

Inductive Effect Of Pyridazine (Pz) On Cytochrome P4502E1 (CYP2E1) Alters The Metabolism Of Trichloroethylene (TCE)

Interactive effects between genetic polymorphisms of CYP2E1 & NAT1 and smoking on the development of lung cancer in Korean

RELATIONSHIPS BETWEEN GENETIC POLYMORPHISMS IN CYP2D6 AND CYP2E1 GENES AND LIVER MICROSOMAL DRUG OXIDATION ACTIVITIES-STUDIES …

AhR Mediated Hematotoxicity Is Induced At The Site Of Bone Marrow Where Consequent CYP2E1-Derived Benzene Metabolites Locally Induce Their Toxicity

The potent protective effect of red ginseng against acetaminophen-induced toxicity through metabolic regulation of CYP2E1 and GSTs

CYP2E1 overexpression up-regulates both non-specific ô-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1

Effects of CYP Inducers and Inhibitors on the Furosemide Pharmacokinetics: Involvement of CYP2E1 and 3A 1/2 for the Furosemide Metabolism

Effect of tobacco smoke on the expression of Cyp1a, Cyp2b, Cyp2e, and Cyp3a subfamilies in mice. Possible role of CYP2E1 in pulmonary DNA single strand breaks …

Proteomics of oxidative stress using inducible CYP2E1 expressing HEPG2 cells and 3T3-L1 adipocytes as model systems

An estimate of polymorphism of ADH1B, ALDH2, and CYP2E1 alcohol biotransformation genes in Siberian indigenous and immigrant populations

Effects of in vivo hepatic ischemia‐reperfusion injury on the CYP2E1‐mediated metabolism of chlorzoxazone and biliary clearance of its metabolite in isolated …

Assessment of the role of cytochrome P450 2E1 (CYP2E1)-mediated metabolism in urethane-induced cell proliferation and gene expression: Biomarkers of …

Effect of the South African traditional meat, biltong, on cancer-associated enzymes CYP2E1 and CYP1A2

… of twelve chlorinated aliphatic hydrocarbons upon the cell cycle of Chinese hamster cell lines: V79d-MZ and genetically engineered cell lines expressing CYP2E1

Association of the CYP2E1, FMO3, NQO1, GST, NOS3 genetic polymorphisms with ischemic stroke risk in Turkish population

Alkyl sulfides Potentiation of Carbon Tetrachloride-induced Hepatotoxicity: The Role of CYP2E1 Expression

The influence of alcohol on acetaminophen hepatotoxicity: CYP2E1 induction and selective mitochondrial glutathione depletion

Interaction of genetic polymorphisms of glutathione S-transferase (GST) M1, GSTT1, and CYP2E1 in development of lung cancer

A dietary ethanol protocol for CYP2E1 induction in CD-1 mice and its application to studies on the genotoxicity, immunotoxicity and metabolism of low-level benzene

A Composition of Metadoxine and Garlic Oil Abrogates Alcoholic Steatosis and CYP2E1 Induction in Rat Liver with AMPK Restoration

The Association between Pneumoconiosis and Genetic Polymorphism of GSTM1, GSTT1, GSTP1, NAT2, CYP2E1 and CYP1A1

The effect of trans-resveratrol analogues on the catalytic activities of CYP1A2 and CYP2E1 in mouse liver microsomes in vitro

Genetic Polymorphisms of NAT2, CYP2C9, CYP2C19, CYP2D6 and CYP2E1, and Antituberculosis Drugs Induced Maculopapular Eruption

Alterations in toxicokinetics of trichloroethylene (TCE) and trichloroacetic acid (TCA) due to cytochrome P450 2E1 (CYP2E1) induction

The Role of Genetic Polymorphisms of CYP2E1, CYP1A1, NAT1, and NAT2 in Bladder Cancer in Korea

Effects of benzene on liver, kidney and lung cyp1a, cyp2b4, CYP2E1 and cyp3a6 mrna, protein level, and drug metabolizing enzyme activities and toxicity in diabetic …

Diphenyl-Dimethyl-Dicarboxylate Inhibits Carbon tetrachloride-induced Increase Kupffer Cell Counts in the Absence of CYP2E1 Suppression in the Rat

Diallyl Sulfone, a Derivative of Garlic, Inactivates the Cytochrome P450 Enzyme CYP2E1 by Forming N-alkylprotoporphyrin Heme Adducts

EFFECTS OF STRUCTURALLY AND FUNCTIONALLY DIVERSE GROUP OF PHYTOCHEMICALS ON ANILINE HYDROXYLATION (CYP2E1) OF CONTROL AND …

… Cytochrome P450 Reductase-null Mice as an Animal Model to Study Electron Transfer Pathways in Cholesterol Synthesis and CYP2E1-mediated Drug Metabolism

MATERNAL SMOKING, POLYMORPHISMS IN CYP1A1, CYP2E1, EPHX1, NAT2, NQO1, AND CHILDHOOD ACUTE LEUKEMIA

Evaluation of influence of Andrographis paniculata on activities of CYP1A2, CYP3A4, CYP2E1 and CYP2C19 genotypes in chickens by multiple cytochrome P450 …

Saponins Isolated from the Root of Platycodi Radix Abrogates Alcoholic Steatosis and CYP2E1 Induction in Rat Liver with Restoration of AMPK Activity

Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP1B1, CYP2E1, GSTM1, GSTT1, and NAT2) and p53 gene point mutations …

Identification of 2‐Piperidone as a Biomarker of CYP2E1 Activity through Metabolomic Phenotyping

The effects of the ALDH2* 1/2, CYP2E1 c1/c2 and C/D genotypes on blood ethanol elimination and the human serotonin receptor (HTR2) gene Msp1 polymorphism in …

Elimination rate of 6-hydroxychlorzoxazone in urine as a non-invasive evaluation of cytochrome CYP2E1 activity. Lack of relationship to smoking

IL-4 promotes experimental drug-induced hepatitis by reducing immune responses to haptenated proteins and inhibiting regulatory responses to native CYP2E1 …

Computational Docking Investigations of Oxidative Metabolism of 4-Nitroanisole with CYP2E1

CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease

The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system

The Role of CYP2E1 in the Drug Metabolism or Bioactivation in the Brain

Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis

Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling

New insight and potential therapy for NAFLD: CYP2E1 and flavonoids

A systematic evaluation of microRNAs in regulating human hepatic CYP2E1

Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells

CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis

Induction of CYP2E1 in non-alcoholic fatty liver diseases

Molecular dynamics simulations of CYP2E1

Morbidly obese patients exhibit increased CYP2E1-mediated oxidation of acetaminophen

CCl4-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat

Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness

Higher CYP2E1 activity correlates with hepatocarcinogenesis induced by diethylnitrosamine

CYP2E1 autoantibodies in liver diseases

Role of CYP2E1 in mitochondrial dysfunction and hepatic injury by alcohol and non-alcoholic substances

CYP2E1 in alcoholic and non-alcoholic liver injury. Roles of ROS, reactive intermediates and lipid overload

Impairment of Akt activity by CYP2E1 mediated oxidative stress is involved in chronic ethanol-induced fatty liver

Induction of brain CYP2E1 by chronic ethanol treatment and related oxidative stress in hippocampus, cerebellum, and brainstem

Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway

Ethanol‐induced oxidative stress via the CYP2E1 pathway disrupts adiponectin secretion from adipocytes

Association of NAT2, GST and CYP2E1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity

Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis

Autophagy protects against CYP2E1/chronic ethanol-induced hepatotoxicity

NF-κB-mediated regulation of rat CYP2E1 by two independent signaling pathways

The effect of quercetin on the pharmacokinetics of chlorzoxazone, a CYP2E1 substrate, in healthy subjects

Downregulation of CYP2E1 is associated with poor prognosis and tumor progression of gliomas

Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction

… psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1

Nrf2 and antioxidant defense against CYP2E1 toxicity

Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability

MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity

Plasma exosomes exacerbate alcohol-and acetaminophen-induced toxicity via CYP2E1 pathway

Antioxidant and pro-oxidant mechanisms of (+) catechin in microsomal CYP2E1-dependent oxidative stress

Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis …

Chronic alcohol intake-induced oxidative stress and apoptosis: role of CYP2E1 and calpain-1 in alcoholic cardiomyopathy

Mouse spermatocytes express CYP2E1 and respond to acrylamide exposure

Toward a systems approach to cytochrome P450 ensemble: interactions of CYP2E1 with other P450 species and their impact on CYP1A2

Period1 mediates rhythmic metabolism of toxins by interacting with CYP2E1

Involvement of CYP2E1-ROS-CD36/DGAT2 axis in the pathogenesis of VPA-induced hepatic steatosis in vivo and in vitro

Sulforaphane induces Nrf2 and protects against CYP2E1-dependent binge alcohol-induced liver steatosis

Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study

Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol

CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid

Protective effects of taraxasterol against ethanol-induced liver injury by regulating CYP2E1/Nrf2/HO-1 and NF-κB signaling pathways in mice

Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and …

CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment

Protective effects of diallyl disulfide against acetaminophen-induced nephrotoxicity: a possible role of CYP2E1 and NF-κB

Low doses of curcumin protect alcohol-induced liver damage by modulation of the alcohol metabolic pathway, CYP2E1 and AMPK

Toxicological implications of mitochondrial localization of CYP2E1

Alcoholic liver disease: from CYP2E1 to CYP2A5

Investigation of indazole unbinding pathways in CYP2E1 by molecular dynamics simulations

CYP2E1, GSTM1 and GSTT1 genetic polymorphisms and susceptibility to antituberculosis drug‐induced hepatotoxicity: a nested case–control study

Sex steroid hormones regulate constitutive expression of CYP2E1 in female mouse liver

Antioxidant Properties of Proanthocyanidins Attenuate Carbon Tetrachloride (CCl4)–Induced Steatosis and Liver Injury in Rats via CYP2E1 Regulation

… effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress

Antioxidant Peptides from Protein Hydrolysate of Microalgae Navicula incerta and their Protective Effects in Hepg2/CYP2E1 Cells Induced by Ethanol

Genetic Polymorphisms of Genes Coding to Alcohol‐Metabolizing Enzymes in Western Mexicans: Association of CYP2E1*c2/CYP2E1*5B Allele with Cirrhosis and …

Ethanol-induced oxidative stress is associated with EGF receptor phosphorylation in MCF-10A cells overexpressing CYP2E1

Role and importance of polymorphisms with respect to DNA methylation for the expression of CYP2E1 enzyme

Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates

Potential pathogenetic link between angiomyofibroblastoma and superficial myofibroblastoma in the female lower genital tract based on a novel MTG1-CYP2E1 fusion

CYP2E1 epigenetic regulation in chronic, low-level toluene exposure: Relationship with oxidative stress and smoking habit

The association between CYP2E1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs: a meta-analysis

Binge alcohol promotes hypoxic liver injury through a CYP2E1–HIF-1α-dependent apoptosis pathway in mice and humans

Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPARα-mediated lipogenic gene …

Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress …

CYP2E1 metabolism of styrene involves allostery

ROS generated by CYP450, especially CYP2E1, mediate mitochondrial dysfunction induced by tetrandrine in rat hepatocytes

Sex‐dependent regulation of cytochrome P450 family members Cyp1a1, CYP2E1, and Cyp7b1 by methylation of DNA

The WNT/β-catenin pathway is a transcriptional regulator of CYP2E1, CYP1A2, and aryl hydrocarbon receptor gene expression in primary human hepatocytes

Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis

Association of CYP2E1 gene polymorphisms with bladder cancer risk: A systematic review and meta-analysis

CYP2E1 regulates the development of radiation-induced pulmonary fibrosis via ER stress-and ROS-dependent mechanisms

CYP2E1*5B, CYP2E1*6, CYP2E1*7B, CYP2E1*2, and CYP2E1*3 Allele Frequencies in Iranian Populations

Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression

Investigating the CYP2E1 potential role in the mechanisms behind INH/LPS-induced hepatotoxicity

Enantioselective metabolism of phenylpyrazole insecticides by rat liver microsomal CYP3A1, CYP2E1 and CYP2D2

CYP2E1 changes the biological function of gastric cancer cells via the PI3K/Akt/mTOR signaling pathway

CYP2E1 hydroxylation of aniline involves negative cooperativity

Salidroside protects mice against CCl4-induced acute liver injury via down-regulating CYP2E1 expression and inhibiting NLRP3 inflammasome activation

Refined CYP2E1∗ Template∗∗ system to decipher the ligand-interactions

Functional PstI/RsaI Polymorphism in CYP2E1 Is Associated with the Development, Progression and Poor Outcome of Gastric Cancer

CYP2E1 RsaI/PstI polymorphism and risk of anti-tuberculosis drug-induced liver injury: a meta-analysis

Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences

Effect of ammonium pyrrolidine dithiocarbamate (PDTC) on NF-κB activation and CYP2E1 content of rats with immunological liver injury

Prilocaine-and lidocaine-induced methemoglobinemia is caused by human carboxylesterase-, CYP2E1-, and CYP3A4-mediated metabolic activation

CYP2E1 sensitizes the liver to LPS-and TNF α-induced toxicity via elevated oxidative and nitrosative stress and activation of ASK-1 and JNK mitogen …

Induction of SIRT1 by melatonin improves alcohol‐mediated oxidative liver injury by disrupting the CRBN‐YY1‐CYP2E1 signaling pathway

Human CYP2A6, CYP2B6, and CYP2E1 atropselectively metabolize polychlorinated biphenyls to hydroxylated metabolites

Why hepatic CYP2E1-elevation by itself is insufficient for inciting NAFLD/NASH: Inferences from two genetic knockout mouse models

Amalgamation of in-silico, in-vitro and in-vivo approach to establish glabridin as a potential CYP2E1 inhibitor

Roles of CYP2E1 in 1, 2‐dichloroethane‐induced liver damage in mice

High CYP2E1 activity correlates with hepatofibrogenesis induced by nitrosamines

Baicalin ameliorates liver injury induced by chronic plus binge ethanol feeding by modulating oxidative stress and inflammation via CYP2E1 and NRF2 in …

Relevance of CYP2E1 to non-alcoholic fatty liver disease

Higher sensitivity of female cells to ethanol: methylation of DNA lowers CYP2E1, generating more ROS

Protective effects of protein hydrolysate from marine microalgae Navicula incerta on ethanol-induced toxicity in HepG2/CYP2E1 cells

Single-nucleotide polymorphisms in cytochrome P450 2E1 (CYP2E1) 3′-untranslated region affect the regulation of CYP2E1 by miR-570

CYP2E1 polymorphisms and nasopharyngeal carcinoma risk: a meta-analysis

The importance of CYP2E1 in the pathogenesis of alcoholic liver disease and drug toxicity and the role of the proteasome

Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in a Chinese Tibetan population

Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice

Polydatin protects rat liver against ethanol-induced injury: involvement of CYP2E1/ROS/Nrf2 and TLR4/NF-B p65 pathway

CYP2E1 in the human retinal pigment epithelium: expression, activity, and induction by ethanol

Relationship of anti-tuberculosis drug-induced liver injury and genetic polymorphisms in CYP2E1 and GST

Effect of piperine on CYP2E1 enzyme activity of chlorzoxazone in healthy volunteers

… final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: role of CYP2E1 and Keap1-Nrf2 …

Genetic Variability in CYP2E1 and Catalase Gene Among Currently and Formerly Alcohol-Dependent Male Subjects

CYP2E1 induction leads to oxidative stress and cytotoxicity in glutathione-depleted cerebellar granule neurons

Subcellular localization of rat CYP2E1 impacts metabolic efficiency toward common substrates

Contributing roles of CYP2E1 and other cytochrome P450 isoforms in alcohol-related tissue injury and carcinogenesis

Stat4 rs7574865 polymorphism promotes the occurrence and progression of hepatocellular carcinoma via the Stat4/CYP2E1/FGL2 pathway

Effects of acrylamide on oxidant/antioxidant parameters and CYP2E1 expression in rat pancreatic endocrine cells

CYP2E1 polymorphisms and colorectal cancer risk: a HuGE systematic review and meta-analysis

Alcohol-induced CYP2E1, mitochondrial dynamics and retrograde signaling in human hepatic 3D organoids

CYP2E1 gene promoter polymorphism-1293G> C increases the risk of essential hypertension in men with alcohol abuse

Polymorphisms in NEIL-2, APE-1, CYP2E1 and mdm2 genes are independent predictors of gastric cancer Risk in a Northern Jiangsu Population (China)

Interactions of inhibitor molecules with the human CYP2E1 enzyme active site

Resveratrol pretreatment affects CYP2E1 activity of chlorzoxazone in healthy human volunteers

Role of CYP2E1-mediated metabolism in the acute and vestibular toxicities of nineteen nitriles in the mouse

Induction of CYP2E1 in testes of isoniazid-treated rats as possible cause of testicular disorders

A case control study on relationship between lung cancer and genetic polymorphism of CYP1A1, CYP2E1 and GSTM1 in Han Nationality in Guangzhou area

A case control study on the impact of CYP2E1 and GST-M1 polymorphisms on the risk of lung cancer

A Case–control and a family-based association study revealing an association between CYP2E1 polymorphisms and nasopharyngeal carcinoma risk …

A case-control study of CYP2E1 (PstI) and CYP1A1 (MspI) polymorphisms in colorectal cancer

A Case-Control Study on Effects of Genetic Polymorphisms of GSTM1, GSTT1, CYP1A1 and CYP2E1 on Risk of Lung Cancer.

A comparison of substrate dynamics in human CYP2E1 and CYP2A6

A comparison of the inhibitory effects of four volatile anaesthetics on the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits

A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1

A dietary ethanol protocol for CYP2E1 induction in CD-1 mice and its application to studies on the genotoxicity, immunotoxicity and metabolism of low-level benzene.

A Haplotype Analysis of CYP2E1 Polymorphisms in Relation to Alcoholic Phenotypes in Mexican Americans

A High Throughput Screening Assay to Screen for CYP2E1 Metabolism and Inhibition Using a Fluorogenic Vivid® P450 Substrate

A Meta-analysis of CYP2E1 Genetic Polymorphism and Gastric Cancer Susceptibility [J]

A meta-analysis on association of CYP2E1 rs2031920 and rs3813867 polymorphisms with breast cancer risk

A multiplex-PCR/RFLP procedure for simultaneous CYP2E1, mEH and GSTM1 genotyping

A Nanosensor System Based On Disuccinimydyl–CYP2E1 for Amperometric Detection of the Anti-Tuberculosis Drug, Pyrazinamide

A negative cooperativity mechanism of human CYP2E1 inferred from molecular dynamics simulations and free energy calculations

A novel lipopolysaccharide‐modulated Jun binding repressor in intron 2 of CYP2E1

A novel polymorphism rs1329149 of CYP2E1 and a known polymorphism rs671 of ALDH2 of alcohol metabolizing enzymes are associated with colorectal cancer in a …

A novel role of CYP2E1 in human megakaryocyte development

A polymorphism in the 5′-flanking region of the CYP2E1 gene and elevated lung adenocarcinoma risk in a Japanese population

A reaction network model for CYP2E1-mediated metabolism of toxicant mixtures

A regulatory variant in CYP2E1 affects the risk of lung squamous cell carcinoma

A relationship between genetic polymorphisms of CYP2E1 and susceptibility of acute leukemia in Gansu population

A significantly joint effect between arsenic and occupational exposures and risk genotypes/diplotypes of CYP2E1, GSTO1 and GSTO2 on risk of urothelial carcinoma

A single nucleotide polymorphism in the CYP2E1 gene promoter affects skatole content in backfat of boars of two commercial Duroc-sired crossbred populations

A study for regulation of ethanol-inducible P450(CYP2E1) on CCl4-induced hepatic damage

A study on the effects of Lauric acid on ROS formation and CYP2E1 mRNA expression in alcohol-induced HEPG2 cells

A Study on the Optimization of CYP2E1 Enzyme Activity in C57Bl/6 Mouse Brain and Liver/C57Bl/6 Fare Beyin ve Karaciger Mikrozomlarinda CYP2E1 Enzim …

A systematic evaluation of microRNAs in regulating human hepatic CYP2E1

A systematically combined genotype and functional combination analysis of CYP2E1, CYP2D6, CYP2C9, CYP2C19 in different geographic areas of mainland …

A temporal study on the histopathological, biochemical and molecular responses of CCl4-induced hepatotoxicity in CYP2E1-null mice

A-71G> T Nucleotide Substitution uncouples IFN-[gamma]-dependent Suppression of CYP2E1 mRNA

Abnormal liver function associated with polymorphism of GSTT1, GSTM1 and CYP2E1 in workers exposed to N, N-dimethylformamide

Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect

Acetaldehyde as a substrate for ethanol-inducible cytochrome P450 (CYP2E1)

Acetaldehyde as well as ethanol is metabolized by human CYP2E1

Acetaldehyde generating enzyme systems: roles of alcohol dehydrogenase, CYP2E1 and catalase, and speculations on the role of other enzymes and processes

Acetaminophen alters microsomal ryanodine Ca2+ channel in HepG2 cells overexpressing CYP2E1

Acetaminophen and Isoniazid treatment leads to oxidative stress and cytotoxicity in cerebellar granule neurons possibly by CYP2E1 activation

Acetoacetate induces CYP2E1 protein and suppresses CYP2E1 mRNA in primary cultured rat hepatocytes

Acetone catabolism by cytochrome P450 2E1: studies with CYP2E1-null mice

Aconitine, a famous active and toxic alkaloid, has no impact on the activities of CYP1A2, CYP2D6, CYP2E1, and CYP3A in rats

Action-mechanisms of Genetic Polymorphism in the CYP2E1 on Susceptibility to Polycyclic Aromatic Hydrocarbons

Activation of alkylhydrazines to free radical intermediates by ethanol-inducible cytochrome P-4502E1 (CYP2E1)

Activity of CYP2E1 and CYP3A enzymes in adults with moderate alcohol consumption: a comparison with nonalcoholics

Activity of immobilised rat hepatic microsomal CYP2E1 using alumina membrane as a support

Acute ethanol pretreatment increases FAS-mediated liver injury in mice: role of oxidative stress and CYP2E1-dependent and-independent pathways

Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes

Adenovirus mediated overexpression of CYP2E1 increases sensitivity of HepG2 cells to acetaminophen induced cytotoxicity

Adenovirus‐mediated expression of Cu/Zn‐or Mn‐superoxide dismutase protects against CYP2E1‐dependent toxicity

Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice

ADH2 and CYP2E1 genetic polymorphisms: risk factors for alcohol-related birth defects

Administration of the tris salt of α-tocopheryl hemisuccinate inactivates CYP2E1, enhances microsomal α-tocopherol levels and protects against carbon tetrachloride …

Advances in the interpretation and prediction of CYP2E1 metabolism from a biochemical perspective

Adverse Birth Outcomes Associated with Maternal Smoking and Polymorphisms in the N-Nitrosamine-Metabolizing Enzyme Genes NQO1 and CYP2E1

Age-dependent features of CYP3A, CYP2C, and CYP2E1 functioning at metabolic syndrome

Ageing is associated with increased expression but decreased activity of CYP2E1 in male Wistar rats

Age-related changes in the protein and mRNA levels of CYP2E1 and CYP3A isoforms as well as in their hepatic activities in Wistar rats. What role for oxidative stress?

ALCOHOL AND CANCER SY05-1 CARCINOGENIC ETHENO DNA ADDUCTS GENERATED DURING INFLAMMATION AND CYP2E1 INDUCTION IN VARIOUS …

Alcohol intake and folate antagonism via CYP2E1 and ALDH1: Effects on oral carcinogenesis

Alcohol Suppresses Cardiovascular Diurnal Variations In Male Normotensive Rats: Role Of Reduced PER2 Expression And CYP2E1 Hyperactivity In The Heart

Alcoholic liver disease: from CYP2E1 to CYP2A5

Alcohol-Induced Increase in the Content of CYP2E1 in Human Liver Microsomes Causes a Multifold Activation of CYP3A4 and Attenuates its Cooperativity

ALDH2 and CYP2E1 genotypes, urinary acetaldehyde excretion and the health consequences in moderate alcohol consumers

All trans retinoic acid modulates TNF-α and CYP2E1 pathways and enhances regression of ethanol-induced fibrosis markers in hepatocytes and HSCs in abstaining …

Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian …

ALLELIC VARIANTS OF CYP2E1 GENE IN HEPATOCARCINOMA PATIENTS AND IN HEPATIC TUMOR CELL LINES

Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse

Alteration in the expression of cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the liver of mouse induced by microcystin-LR

Alterations in toxicokinetics of trichloroethylene (TCE) and trichloroacetic acid (TCA) due to cytochrome P450 2E1 (CYP2E1) induction

Altered ethylbenzene-mediated hepatic CYP2E1 expression in growth hormone-deficient dwarf rats

Amelioration of oxidative stress by dandelion extract through CYP2E1 suppression against acute liver injury induced by carbon tetrachloride in sprague‐dawley rats

An estimate of polymorphism of ADH1B, ALDH2, and CYP2E1 alcohol biotransformation genes in Siberian indigenous and immigrant populations

An improved in vitro method for screening toxin and medicine targeting CYP2E1

An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A)

An investigation of CYP2E1 phenotype determination utilizing modeling and simulation studies

An investigation of the induction of hepatic CYP2E1 by low doses of nicotine in the rat.

An Rsa I Polymorphism in the CYP2E1 Gene Does Not Affect Lung Cancer Risk in a Japanese Population

An Updated Meta-Analysis On CYP2E1 RsaI/PstI And DraI Polymorphisms And Risk Of Anti-Tuberculosis Induced Hepatotoxicity: Evidence From 26 Studies

Analysis of CYP2E1 and GSTM1 polymorphisms for the determination of genetic susceptibility to Korean patients with colon cancer

Analysis of CYP2E1 polymorphism for the determination of genetic susceptibility to gastric cancer in Koreans

Analysis of CYP2E1, GSTM1 genetic polymorphisms in relation to human lung cancer and esophageal carcinoma

Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling

Analysis of ethanol metabolic enzymes in primary human mammary epithelial cells and MCF‐10A cells: possible participation of CYP2E1 in ethanol‐induced oxidative …

Analysis of human CYP2E1 mRNA in a HepG2 cell line by reverse transcription-polymerase chain reaction (RT-PCR)

Analysis of point mutation in exon 2 of CYP2E1 gene in renal cell/urothelial cancer patients in comparison with control population.

Analysis of protein and mRNA expressions of CYP1A1, CYP2E1, NQO1 and GST enzymes in liver, colon and prostate cancer cell lines to study drug and …

and CYP2E1 and N‐terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae − role of protein kinase A in the mitochondrial targeting of CYP2E1

Antibiotic furazolidone induces CYP1A but not CYP2E1 subfamily in rat liver

Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity

Antioxidant and pro-oxidant mechanisms of (+) catechin in microsomal CYP2E1-dependent oxidative stress

Antioxidant Peptides from Protein Hydrolysate of Microalgae Navicula incerta and their Protective Effects in Hepg2/CYP2E1 Cells Induced by Ethanol

Antioxidant Properties of Proanthocyanidins Attenuate Carbon Tetrachloride (CCl4)–Induced Steatosis and Liver Injury in Rats via CYP2E1 Regulation

Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPARα-mediated lipogenic gene …

APOE and CYP2E1 polymorphisms, alcohol consumption, and Parkinson’s disease in a Japanese population

Application of a map Bayesian method for CYP2E1 phenotyping

Application of an updated physiologically based pharmacokinetic model for chloroform to evaluate CYP2E1-mediated renal toxicity in rats and mice

Area Under the Plasma Concentration–Time Curve of Inorganic Fluoride Following Sevoflurane Anesthesia Correlates with CYP2E1 mRNA Level in …

Aspartame administration and insulin treatment altered brain levels of CYP2E1 and CYP3A2 in streptozotocin-induced diabetic rats

Assessing Specificity of Indazole Derivatives as Inhibitors to CYP2E1

Assessment of frequencies of lifestyle factors and polymorphisms of drug-metabolizing enzymes (NAT2, CYP2E1) in human hepatocellular carcinoma (HCC) patients …

Association analysis of alcohol metabolizing enzymes ADH1B, ADH7, CYP2E1 gene polymorphism with risk for coronary atherosclerosis

Association analysis of SNPs in the porcine CYP2E1 gene with skatole, indole, and androstenone levels in backfat of a crossbred pig population

Association between CYP2E1 and GOT2 gene polymorphisms and susceptibility and low-dose N,N-dimethylformamide occupational exposure-induced liver injury

Association between CYP2E1 genetic polymorphisms and lung cancer risk: a meta-analysis

Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma

Association between CYP2E1 polymorphisms and risk of gastric cancer: An updated meta‑analysis of 32 case‑control studies

Association between genetic polymorphism of GSTM1, CYP2E1 and susceptibility to cervical cancer and its precancerous lesions in Uighur women in Xinjiang

Association between genetic polymorphisms of CYP2E1 and lung cancer susceptibility: a case control study

Association between genetic variants in CYP2E1 and CTRC genes and susceptibility to alcoholic pancreatitis: A systematic review and meta-analysis

Association between polymorphism of GSTP1, GSTT1, GSTM1 and CYP2E1 genes and susceptibility to benzene-induced hematotoxicity

Association between polymorphisms in the CYP1A1, CYP2E1 and GSTM1 genes, and smoking, alcohol and upper digestive tract carcinomas in a high …

Association between the CYP2E1 polymorphisms and lung cancer risk: a meta-analysis

Association between the TP53 and CYP2E1* 5B gene polymorphisms and non-small cell lung cancer

Association of CYP2E1 and CYP1A1m2 (BsrD1) polymorphisms with cytogenetic biomarkers in petrol pump workers

Association of CYP2E1 and NAT2 gene polymorphisms with chronic obstructive pulmonary disease

Association of CYP2E1 gene polymorphism with predisposition to cancer development

Association of CYP2E1 gene polymorphisms with bladder cancer risk: A systematic review and meta-analysis

Association of CYP2E1 of PON2311 polymorphisms in neonates with preterm

Association of CYP2E1, GST and mEH genetic polymorphisms with urinary acrylamide metabolites in workers exposed to acrylamide

Association of CYP2E1, NQO1 and GST genetic polymorphisms with risk of acute lymphoblastic leukemia in turkish children

Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning.

Association of genetic polymorphisms of CYP2E1, NAT2, GST and SLCO1B1 with the risk of anti-tuberculosis drug-induced liver injury: a systematic review and meta …

Association of GSTM1, CYP1A1 and CYP2E1 genetic polymorphisms with susceptibility to lung adenocarcinoma: A case‐control study in Chinese population

Association of GSTM1, GSTT1 and CYP2E1 gene polymorphisms with antituberculosis drug induced hepatotoxicity in North Indian population

Association of GSTM1, GSTT1, GSTP1 and CYP2E1 single nucleotide polymorphisms with colorectal cancer in Iran

Association of mitochondrial deoxyribonucleic acid mutation with polymorphism in CYP2E1 gene in oral carcinogenesis

Association of NAT2, GST and CYP2E1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity

Association of radiation risk in the second and third generations with polymorphisms in the genes CYP1A1, CYP2E1, GSTP1 and changes in the thyroid

Association of the blood biochemical index with CYP2E1 5’flanking region Rsa I/Pst I gene polymorphism and alcohol consumption habit in Southern Taiwan …

Association of the CYP2E1, FMO3, NQO1, GST, NOS3 genetic polymorphisms with ischemic stroke risk in Turkish population

Association Studies of Polymorphisms of CYP2E1 Gene in Alcoholics with Cirrhosis, Antisocial Personality, and Normal Controls

Associations between CYP1A1 and CYP2E1 polymorphisms and susceptibility to esophageal cancer in Chaoshan and Taihang areas of China

Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratio

Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratios

Associations of CYP1A1, GSTM1, and CYP2E1 polymorphisms with lung cancer suggest cell type specificities to tobacco carcinogens

Associations of CYP2E1 rs2031920 and rs3813867 polymorphisms with colorectal cancer risk: a systemic review and meta-analysis

Associations of Rsa I polymorphism at the 5’flanking region of CYP2E1 and PON2 148 polymorphism in neonates with preterm delivery

Author Correction: Effect of BI-1 on insulin resistance through regulation of CYP2E1

Author’s Reply to Reith:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”

Autophagy protects against CYP2E1/chronic ethanol-induced hepatotoxicity

B107 TUBERCULOSIS: ISSUES DURING TREATMENT: An Updated Meta-Analysis On CYP2E1 Rsai/psti And Drai Polymorphisms And Risk Of Anti-Tuberculosis …

Baicalin ameliorates liver injury induced by chronic plus binge ethanol feeding by modulating oxidative stress and inflammation via CYP2E1 and NRF2 in …

Benzene-induced genotoxicity in mice in vivo detected by the alkaline comet assay: reduction by CYP2E1 inhibition

bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in …

Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation

Binge alcohol promotes acute liver injury through a CYP2E1‐HIF‐1α‐dependent apoptosis pathway in mice and humans (1010.1)

Binge alcohol promotes hypoxic liver injury through a CYP2E1–HIF-1α-dependent apoptosis pathway in mice and humans

Bioactivation of 1, 1-dichloroethylene by CYP2E1 and CYP2F2 in murine lung

Bioactivation of 1, 1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes

Bioinformatic Analysis of the Main Characteristics and Structure of the Gene Encoding CYP2E1 Protein.

Bioinformatics of CYP2E1 CpG intron methylation sites and application to HAR1-RELN sequence analysis

Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1.

Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription

Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics

Breaking self-tolerance toward cytochrome P4502E1 (CYP2E1) in chronic hepatitis C: possible role for molecular mimicry

Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice

by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and Rat CYP2A3

Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1

Camelus dromedarius Putative Cytochrome P450 Enzyme CYP2E1: Complete Coding Sequence and Phylogenetic Tree

Caralluma umbellata Haw. protects liver against paracetamol toxicity and inhibits CYP2E1

CARBON MONOXIDE PROTECTS MICROSOMES FROM ETHANOL-DERIVED OXIDATIVE STRESS MEDIATED BY CYP2E1

Case Control Study of Genetic Polymorphism of Cytochrome P4502E1 5′(CYP2E1 5′) and Susceptibility of Occupational Manganism [J]

Case-control study of the polymorphisms of CYP2E1-RsaⅠ and GSTT1 genes and susceptibility to pancreatic cancer

CCl 4-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat

cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse CYP2E1

Cervical cancer and CYP2E1 polymorphisms: implications for molecular epidemiology

Changes in coumarin kinetics and subcellular localization of CYP2E1 contribute to bile duct damage and reduce hepatocellular damage after repeated administration …

Changes of CYP2E1 activity in diabetic rat model

Characterization of a dietary ethanol protocol for CYP2E1 induction in the CD-1 mouse without evident hepatic toxicity or genotoxicity

Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1

Characterization of polymorphisms of genes ADH2, ADH3, ALDH2 and CYP2E1 and relationship to the alcoholism in a Colombian population

Chemical characteristics for optimizing CYP2E1 inhibition

CHIP−/−-Mouse Liver: Adiponectin-AMPK-FOXO-Activation Overrides CYP2E1-Elicited JNK1-Activation, Delaying Onset of NASH: T

Chlormethiazole, an inhibitor of CYP2E1, prevented chemical carcinogen-initiated and alcohol-promoted hepatic carcinongenesis in rats.

Chlorzoxazone as a single sample probe of hepatic CYP2E1 activity in humans

Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1

Chlorzoxazone metabolism by winter flounder liver microsomes: evidence for existence of a CYP2E1-like isoform in teleosts

Chlorzoxazone, a selective probe for phenotyping CYP2E1 in humans

Chlorzoxazone: An in vitro and in vivo substrate probe for liver CYP2E1

Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats

Chronic alcohol intake-induced oxidative stress and apoptosis: role of CYP2E1 and calpain-1 in alcoholic cardiomyopathy

Chronic ethanol and high glucose inducible CYP2E1 mediated oxidative stress leads to greater cellular injury in VL-17A cells: a potential mechanism for liver injury …

Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: Role of CYP2E1 and TNF-α and activation of JNK and P38 MAP kinase

Cloning and bioinformatics revealed molecular characterisation of CYP2E1 gene from bactrian camel (Camelus bactrianus)

Cloning and expression of rat CYP2E1 in Saccharomyces cerevisiae: Detection of genotoxicity of N‐alkylformamides

Cloning and sequence analysis of human embryonic nasopharyngeal epithelial CYP2E1 cDNA

Combined analysis of germline polymorphisms of p53, GSTM1, GSTT1, CYP1A1, and CYP2E1: relation to the incidence rate of cervical carcinoma

Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity

Comment on:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”

Comparative analysis of binding affinities between styrene and mammalian CYP2E1 by bioinformatics approaches

Comparative metabolism and disposition of trichloroethylene in CYP2E1–/–and wild-type mice

Comparing the protective effects of three sulfur compounds against acrylonitrile-induced acute toxicity in CYP2E1-induced rats

Comparison of chlorzoxazone one-sample methods to estimate CYP2E1 activity in humans

Comparison of cytochrome P4502E1 (CYP2E1) activity and hepatic and lymphocyte mRNA expression in patients with chronic hepatitis C

Comparison of genetic polymorphisms of CYP2E1, ADH2, and ALDH2 genes involved in alcohol metabolism in Koreans and four other ethnic groups

Comparison of germ cell mutagenicity in male CYP2E1-null and wild-type mice treated with acrylamide: evidence supporting a glycidamide-mediated effect

Comparison of levels of cytochromes P‐450, CYP1A2, CYP2E1, and their related monooxygenase activities in human surgical liver samples

COMPARISON OF POLYMORPHISM rs2070672 CYP2E1 GENE PROPORTION IN EARLY AND ADVANCED STAGE OF UNDIFFERENTIATED TYPE …

Comparison of the polymorphic regions of the cytochrome P450 CYP2E1 gene of humans and patas and cynomolgus monkeys

Comparison of the susceptibility of wild-type and CYP2E1 knockout mice to the hepatotoxic and pneumotoxic effects of styrene and styrene oxide

Compatible effects of euphorbia and glycyrrhiza on CYP2E1 expression and activity in rat liver

Computational Docking Investigations of Oxidative Metabolism of 4-Nitroanisole with CYP2E1

Computational Docking Simulations of Nitroanisole and Nitrophenol with CYP2E1

Computational docking studies of nitroanisoles and nitrophenols with CYP2E1

Concentration-dependent inhibitory effect of Baicalin on the plasma protein binding and metabolism of chlorzoxazone, a CYP2E1 probe substrate, in rats in …

Conformational anti‐cytochrome P4502E1 (CYP2E1) auto‐antibodies contribute to necro‐inflammatory injury in chronic hepatitis C

Constitutive and inducible expression of hepatic CYP2E1 in leptin-deficient ob/ob mice

Construction and assessment of models of CYP2E1: predictions of metabolism from docking, molecular dynamics, and density functional theoretical calculations

Construction and Identification of miRNA Expression Vector Targeting on Mouse CYP2E1

Construction of a CYP2E1-template system for prediction of the metabolism on both site and preference order

Construction of CRISPR/Cas9-mediated genomic deletion of the CYP2E1 gene in human HEK293FT cell line

Construction of CYP2E1 recombinant adenovirus vector and its anti-tumor effects

Contributing Roles of CYP2E1 and Other Cytochrome P450 Isoforms in Alcohol-Related Tissue Injury and Carcinogenesis

Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation

Contribution of CYP2E1 polymorphism to aging in the mechanical workshop workers

Contribution of CYP2E1 to N-methyl-2-pyrrolidone metabolism

Contribution of the ALDH2 and CYP2E1 genes to flushing response and drinking patterns in Japanese healthy volunteers

Contributions of caspase-8 and-9 to liver injury from CYP2E1-produced metabolites of halogenated hydrocarbons

CONTROL OF BOAR TAINT BY USING GENETIC MARKERS: A SINGLE NUCLEOTIDE POLYMORPHISM IN THE CYP2E1 GENE PROMOTER AFFECTS …

Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures

Correction to The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65

Correction to: CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes

Correlation analyses of ALDH2 and CYP2E1 genetic polymorphism with personality

Correlation between genetic polymorphism in CYP2E1, GST and toxicity of dimethylformamide

CORRELATION BETWEEN GENETIC POLYMORPHISM OF CYP2E1 AND SUSCEPTIBILITY OF ESOPHAGEAL CANCER IN GANSU PROVINCE

Correlation between genetic polymorphisms of CYP2E1 DraⅠ and susceptibility of gastric cancer in Qinghai province

Correlation between genetic polymorphisms of CYP2E1 DraⅠ and susceptibility of gastric cancer in Qinghai province [J]

CORRELATION BETWEEN GENETIC POLYMORPHISMS OF CYP2E1 RSAⅠ AND SUSCEPTIBILITY OF GASTRIC CANCER IN QINGHAI PROVINCE [J]

Correlation between spermatogenesis disorders and rat testes CYP2E1 mRNA contents under experimental alcoholism or type I diabetes

Covalent immobilization of recombinant human cytochrome CYP2E1 and glucose-6-phosphate dehydrogenase in alumina membrane for drug screening applications

Covalent modification and time-dependent inhibition of human CYP2E1 by the meta-isomer of acetaminophen

Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis

Crosstalk between CYP2E1 and CYP3A enzymes and its Possible Involvement in Alcohol‐Drug Interactions.

Cryopreserved porcine hepatocytes: expression and induction of cytochrome P450, isoform CYP2E1

Cutaneous CYP2E1 induction after topical treatment by dexamethasone, ethanol and salicylic acid in mouse.

Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria

CYP17A1 and CYP2E1 variants associated with high altitude polycythemia in Tibetans at the Qinghai-Tibetan Plateau

CYP1A1 and CYP2E1 genotypes and risk of esophageal squamous cell carcinoma in a high-incidence region, Kashmir

CYP1A1 CYP2E1 and GSTM1 polymorphisms are not associated with susceptibility to squamous‐cell carcinoma of the esophagus

CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell …

CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms

CYP1A1, CYP2E1 and gastric cancer risk in a high-incidence Colombian population

CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people

CYP1A1, CYP2E1, and GSTM1 gene polymorphisms and susceptibility to colorectal and gastric cancer among Lebanese

CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head …

CYP1A1, CYP2E1, GSTM1, GSTT1, GSTP1, and TP53 polymorphisms: do they indicate susceptibility to chronic obstructive pulmonary disease and non-small-cell …

CYP1A2* 1C, CYP2E1* 5B, and GSTM1 polymorphisms are predictors of risk and poor outcome in head and neck squamous cell carcinoma patients

CYP1AI and CYP2E1 gene polymorphisms may increase susceptibility to Oral Submucous Fibrosis among betel quid chewers of Eastern India

CYP2A6 and CYP2E1 polymorphisms in a Brazilian population living in Rio de Janeiro

CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism

CYP2E1

CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling

CYP2E1 activity and children with obesity: possible confounding factors

CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease

CYP2E1 activity in cisplatin resistant cancer cells

CYP2E1 activity in patients with alcoholic liver disease

CYP2E1 activity on ARPE-19 cells: New approach to RPE ethanol metabolism

CYP2E1 and ALDH2 Gene Polymorphisms in Squamous Cell Head and Neck

CYP2E1 and ALDH2 gene polymorphisms in squamous cell head and neck cancer in the Turkish population

CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese

CYP2E1 and clinical features in alcoholics

CYP2E1 and CYP3A1/2 gene expression is not associated with the ursodeoxycholate effect on ethanol-induced lipoperoxidation

CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

CYP2E1 and GSTM1 gene polymorphisms, environmental factors, and the susceptibility to lung cancer

CYP2E1 and miRNA‐378a‐3p contribute to acetaminophen‐or tripterygium glycosides‐induced hepatotoxicity

CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population

CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease

CYP2E1 and oxidative liver injury by alcohol

CYP2E1 and Parkinson’s disease in a MPTP-induced C57BL/6 mouse model

CYP2E1 and risk of chemically mediated cancers

CYP2E1 autoantibodies in liver diseases

CYP2E1 changes the biological function of gastric cancer cells via the PI3K/Akt/mTOR signaling pathway

CYP2E1 competes with CYP2B4 for limited NADPH‐Cytochrome P450 Reductase

CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90

CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophaghy in HepG2 E47 cells

CYP2E1 epigenetic regulation in chronic, low-level toluene exposure: Relationship with oxidative stress and smoking habit

CYP2E1 expression in bone marrow and its intra-and interspecies variability: approaches for a more reliable extrapolation from one species to another in the risk …

CYP2E1 expression in human lymphocytes from various ethnic populations

CYP2E1 Expression in Liver of Type 2 Diabetic Rats [J]

CYP2E1 G1532C, NQO1 Pro187Ser, and CYP1B1 Val432Leu polymorphisms are not associated with risk of squamous cell carcinoma of the head and neck

CYP2E1 gene polymorphism and ovarian cancer risk in the Yakut population

CYP2E1 GENE POLYMORPHISM AND SUSCEPTIBILITY OF HEPATOCELLULAR CARCINOMA IN QINGHAI TIBETAN POPULATION

CYP2E1 gene polymorphisms related to the formation of coronary artery lesions in Kawasaki disease

CYP2E1 Gene Promoter Polymorphism -1293G>C Increases the Risk of Essential Hypertension in Men with Alcohol Abuse

CYP2E1 gene rs6413420 polymorphism was first found in the Bouyei ethnic group of China

CYP2E1 Genetic Polymorphism relating to Styrene Metabolism of Korean Workers

CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan

CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis

CYP2E1 genotype and transaminase level of tuberculosis patients receiving fixed dose combination of antituberculosis

CYP2E1 genotypes and serum LAP in Japanese alcoholics

CYP2E1 genotyping in renal cell/urothelial cancer patients in comparison with control populations.

CYP2E1 hydroxylation of aniline involves negative cooperativity

CYP2E1 immunoglobulin G4 subclass antibodies after desflurane anesthesia

CYP2E1 impairs GLUT4 gene expression and function: NRF2 as a possible mediator

CYP2E1 in the human retinal pigment epithelium: expression, activity, and induction by ethanol

CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation

CYP2E1 induction leads to oxidative stress and cytotoxicity in glutathione-depleted cerebellar granule neurons

CYP2E1 inhibition enhances mallory body formation

CYP2E1 is a central mediator for the synergistic effects of alcohol and free fatty acids on hepatocellular steatosis and inflammation

CYP2E1 is not involved in early alcohol-induced liver injury

CYP2E1 is preferentially expressed in Clara cells of murine lung: localization by in situ hybridization and immunohistochemical methods.

CYP2E1 level in rat liver injured by the interaction between carbon tetrachloride and chloroform

CYP2E1 mediated ethanol metabolism in ARPE-19 cells.

CYP2E1 Mediates Ethanol-Induced DNA Damage And TNF Release In Bronchial Epithelial Cells

CYP2E1 metabolism of styrene involves allostery

CYP2E1 mRNA expression, genetic polymorphisms in peripheral blood lymphocytes and liver abnormalities in Chinese VCM-exposed workers

CYP2E1 mutation associated with increased chlorzoxazone (CZ) metabolic ability

CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling

CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of γ-glutamylcysteine synthetase

CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells

CYP2E1 overexpression up-regulates both non-specific ô-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1

CYP2E1 overexpression up-regulates both non-specific δ-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1

CYP2E1 phenotype in Mexican workers occupationally exposed to low levels of toluene

CYP2E1 polymorphism, acetylator profiles and drug-induced liver injury incidence of Indonesian tuberculosis patients

CYP2E1 polymorphisms and colorectal cancer risk: a HuGE systematic review and meta-analysis

CYP2E1 polymorphisms and gene–environment interactions in the risk of upper aerodigestive tract cancers among Indians

CYP2E1 polymorphisms and nasopharyngeal carcinoma risk: a meta-analysis

CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis

CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment

CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases …

CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis

CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk: a meta-analysis

CYP2E1 PstI/RsaI polymorphism and interaction with alcohol consumption in hepatocellular carcinoma susceptibility: evidence from 1,661 cases and 2,317 controls

CYP2E1 recovery is associated with a pericentral fibrosis pattern after repeated CCl4 insults

CYP2E1 regulation by benzene and other small organic chemicals in rat liver and peripheral lymphocytes

CYP2E1 rs2031920, COMT rs4680 polymorphisms, cigarette smoking, alcohol use and lung cancer risk in a Japanese population

CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking

CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls

CYP2E1 Rsa I/Pst I polymorphism contributes to oral cancer susceptibility: a meta-analysis

CYP2E1 Rsa I/Pst I polymorphism is associated with lung cancer risk among Asians

CYP2E1 RsaⅠpolymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking

CYP2E1 RsaI/PstI polymorphism and gastric cancer susceptibility: meta-analyses based on 24 case-control studies

CYP2E1 Rsai/Psti polymorphisms contributed to oral cancer susceptibility: A meta-analysis

CYP2E1 substrate inhibition mechanistic interpretation through an effector site for monocyclic compounds

CYP2E1 substrate inhibition. MECHANISTIC INTERPRETATION THROUGH AN EFFECTOR SITE FOR MONOCYCLIC COMPOUNDS.

CYP2E1 substrate inhibition..

CYP2E1 T7632A and 9-bp insertion polymorphisms and colorectal cancer risk: a meta-analysis based on 4,592 cases and 5,918 controls

CYP2E1 VNTR genotyping associated to anti–tuberculosis drug-induced hepatotoxicity

CYP2E1 VNTR polymorphisms and hepatocarcinoma: a gender-specific correlation

CYP2E1* 5B, CYP2E1* 6, CYP2E1* 7B, CYP2E1* 2, and CYP2E1* 3 allele frequencies in Iranian populations

CYP2E1, GSTM1 and GSTT1 genetic polymorphisms and susceptibility to antituberculosis drug‐induced hepatotoxicity: a nested case–control study

CYP2E1, oxidative stress and MAPK signaling pathways in alcohol-induced hepatotoxicity

CYP2E1, oxidative stress, post-translational modifications and lipid metabolism

CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury

CYP2E1: from ash to nash

CYP2E1: Mechanism of induction by isoniazid and role in acetaminophen oxidation.

CYP2E1: the anesthesia enzyme

CYP2E1-and TNFalpha/LPS-induced oxidative stress and MAPK signaling pathways in alcoholic liver disease

CYP2E1–Biochemical and Toxicological Aspects and Role in Alcohol-Induced Liver Injury

CYP2E1-catalyzed alcohol metabolism: Role of oxidant generation in interferon signaling, antigen presentation and autophagy

CYP2E1-catalyzed oxidation contributes to the sperm toxicity of 1-bromopropane in mice

CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis

CYP2E1-dependent benzene toxicity: the role of extrahepatic benzene metabolism

CYP2E1-dependent bioactivation of 1, 1-dichloroethylene in murine lung: formation of reactive intermediates and glutathione conjugates

CYP2E1-dependent bioactivation of 1, 1-dichloroethylene to reactive intermediates in murine and human lung and liver microsomes.

CYP2E1-DEPENDENT BIOACTIVATION OF 191

CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid

CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes

CYP2E1-dependent oxidative stress and toxicity: role in ethanol-induced liver injury

CYP2E1-dependent toxicity and oxidative stress in HepG2 cells

CYP2E1-dependent toxicity and up-regulation of antioxidant genes

CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane

CYP2E1-mediated modulation of valproic acid-induced hepatocytotoxicity

CYP2E1‐mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells

CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes

Cytochemical Localization of the Acetone-lnducible Cytochrome P-450 Isoform, CYP2E1 in Murine Colonic Epithelium

Cytochrome b5 coexpression increases the CYP2E1-dependent mutagenicity of dialkylnitrosamines in methyltransferase-deficient strains of Salmonella typhimurium

Cytochrome b5 reductase and cytochrome b5 support the CYP2E1-mediated activation of nitrosamines in a recombinant Ames test

Cytochrome CYP2E1 is critical for joint effects of alcohol and lipids on hepatocellular steatosis and inflammation

Cytochrome CYP2E1 phenotyping and genotyping in the evaluation of health risks from exposure to polluted environments

Cytochrome P450 2E1 (CYP2E1) is essential for acrylonitrile metabolism to cyanide: comparative studies using CYP2E1-null and wild-type mice

Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice

Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells

Cytochrome P450 2E1 (CYP2E1)-dependent production of a 37-kDa acetaldehyde–protein adduct in the rat liver

Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance

Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol‐induced oxidative DNA damage in rodent liver

Cytochrome P450 Genes (CYP2E1 and CYP1A1) Variants and Susceptibility to Chronic Hepatitis B Virus Infection

Cytochrome P450 Reductase-null Mice as an Animal Model to Study Electron Transfer Pathways in Cholesterol Synthesis and CYP2E1-mediated Drug Metabolism

Cytochrome P4502E1 (CYP2E1) expression in peripheral blood lymphocytes: evaluation in hepatitis C and diabetes

Cytochrome P4502E1 (CYP2E1) genetic polymorphism in a case-control study of gastric cancer and liver disease.

Cytochrome P450IIE1 (CYP2E1) is induced by skatole and this induction is blocked by androstenone in isolated pig hepatocytes

Cytochrome p-450-mediated differential oxidative modification of proteins: albumin, apolipoprotein E, and CYP2E1 as targets

D2-receptor-linked signaling pathways regulate the expression of hepatic CYP2E1

Decreased CYP2E1 mRNA expression in human leucocytes in patients with fibrotic and inflammatory lung diseases

Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1

dehydrogenase 2, cytochrome p450 2E1 for liver cancer risk in HCV antibody-positive japanese patients and the variations of CYP2E1 mRNA expression levels in the …

Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1–JNK1 pathway in HepG2 cells

Depression of glutathione content, elevation of CYP2E1-dependent activation, and the principal determinant of the fasting-mediated enhancement of 1, 3-dichloro-2 …

Detection and characterization of novel polymorphisms in the CYP2E1 gene.

Detection of autoantibodies against cytochrome P450 2E1 (CYP2E1) in patients with recurrent hepatitis C

Detection of auto-antibodies against cytochrome P4502E1 (CYP2E1) in chronic hepatitis C

Detection of CYP2E1, a genetic biomarker of susceptibility to benzene metabolism toxicity in immortal human lymphocytes derived from the Han Chinese population

Determination of the activity of human hepatic cytochromes P450 CYP2C8/9, CYP2E1

Development and properties of HepG2 cells that constitutively express CYP2E1

Development of a non-high pressure liquid chromatography assay to determine [14C] chlorzoxazone 6-hydroxylase (CYP2E1) activity in human liver microsomes

Development of an IgY antibody-based immunoassay for the screening of the CYP2E1 inhibitor/enhancer from herbal medicines

Developmental Expression of CYP2E1 in the Human Liver: Hypermethylation Control of Gene Expression During the Neonatal Period

Diallyl sulfide inhibition of CYP2E1 does not rescue diabetic rats from thioacetamide-induced mortality

Diallylsulfide and allylmethylsulfide are uniquely effective among organosulfur compounds in inhibiting CYP2E1 protein in animal models

Dichloroacetic acid treatment increases hepatic CYP2E1 in male and female rats

Dietary aflatoxin B1 intake, genetic polymorphisms of CYP1A2, CYP2E1, EPHX1, GSTM1, and GSTT1, and gastric cancer risk in Korean

Dietary lipids affect human ethanol-inducible CYP2E1 gene expression in vivo in mononuclear cells

Dietary omega-3 polyunsaturated fatty acids alter fatty acid composition of lipids and CYP2E1 expression in rat liver tissue

Differences in butadiene adduct formation between rats and mice not due to selective inhibition of CYP2E1 by butadiene metabolites

Different CYP2E1 genotypes and alcoholic liver disease.

Different regulation and expression of the human CYP2E1 gene due to the Rsal polymorphism in the 5′-flanking region

Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol

Differential effects of diabetes on CYP2E1 and CYP2B4 proteins and associated drug metabolizing enzyme activities in rabbit liver

Differential effects of dietary fatty acids on the regulation of CYP2E1 and protein kinase C in human hepatoma HepG2 cells

Differential expression of cytochrome P4502E1 (CYP2E1) in Morris hepatomas and livers of tumor bearing rats.

Differential expression profile of cytochrome p450 2E1 (CYP2E1) related genes associated with carbon tetrachloride-induced hepatotoxicity

Differential in vivo effects of α‐naphthoflavone and β‐naphthoflavone on CYP1A1 and CYP2E1 in rat liver, lung, heart, and kidney

Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake

Differential metabolism of acrylonitrile to cyanide is responsible for the greater sensitivity of male vs female mice: role of CYP2E1 and epoxide hydrolases

Differential Modulation of CYP2E1 Activity by cAMP-Dependent Protein Kinase upon Ser129Replacement

Differential role of CYP2E1 binders and isoniazid on CYP2E1 protein modification in NADPH-dependent microsomal oxidative reactions: free radical scavenging …

Differential role of CYP2E1-mediated metabolism in the lethal and vestibulotoxic effects of cis-crotononitrile in the mouse

Diminished CYP2E1 expression and formation of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1, 1-dichloroethylene epoxide, in murine lung tumors

Direct sequencing and comprehensive screening of genetic polymorphisms on CYP2 family genes (CYP2A6, CYP2B6, CYP2C8, and CYP2E1) in five ethnic …

Distribution and differential induction of CYP2E1 by ethanol and acetone in the mesocorticolimbic system of rat

Distribution of ADH1B, ALDH2, CYP2E1∗ 6, and CYP2E1∗ 7B genotypes in Turkish population

Distribution of cytochrome CYP2E1 in murine liver after ethanol and acetone administration

DLPC attenuates alcohol-induced cytotoxicity in HepG2 cells expressing CYP2E1

DNA damage and cytotoxicity in pancreatic β-cells expressing human CYP2E1

DNA damage in peripheral blood lymphocytes and association with polymorphisms in the promoter region of the CYP2E1 gene in alcoholics from Central Brazil

DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms significantly contribute to the risk of development of childhood …

Do Endogenous Volatile Organic Chemicals Measured in Breath Reflect and Maintain CYP2E1 Levelsin Vivo?

Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage

Does CYP2E1 play a major role in the aggravation of isoniazid toxicity by rifampicin in human hepatocytes?

Does CYP2E1 RsaI/PstI polymorphism confer head and neck carcinoma susceptibility?: A meta-analysis based on 43 studies

Downregulation of the CYP2E1 ameliorates oxidative stress and apoptosis

Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells

Drinking Water Chlorination By-Products and Intra-Uterine Growth Restriction: is there an effect modification of the CYP2E1 G1259C gene polymorphism?

Duration of cytochrome P-450 2E1 (CYP2E1) inhibition and estimation of functional CYP2E1 enzyme half-life after single-dose disulfiram administration in humans

e0048 CYP2E1 increases oxidative stress and induces apoptosis of cardio myocytes in transgenic mice

Early Alcoholic Liver Injury: Formation of Protein Adducts with Acetaldehyde and Lipid Peroxidation Products, and Expression of CYP2E1 AND CYP3A

Effect of {gamma}-irradiation and mitomycin C (MMC) on CYP2B1 and CYP2E1 activities in rat hepatic microsomes in vitro

Effect of 1-aminobenzotriazole on the in vitro metabolism and single-dose pharmacokinetics of chlorzoxazone, a selective CYP2E1 substrate in Wistar rats

effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress

Effect of ALDH2 and CYP2E1 Gene Polymorphisms on Drinking Behavior and Alcoholic Liver Disease in Japanese Male Workers

Effect of ammonium pyrrolidine dithiocarbamate (PDTC) on NF-κB activation and CYP2E1 content of rats with immunological liver injury

Effect of antifungal drugs on cytochrome P450 (CYP) 1A2, CYP2D6, and CYP2E1 activities in human liver microsomes

Effect of BI-1 on insulin resistance through regulation of CYP2E1

Effect of Capsosiphon fulvescens on ethanol-induced liver damage in HepG2 cells over expressing CYP2E1

Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N‐acetyltransferase in healthy human subjects

Effect of cigarette smoke on hepatic and pulmonary cytochromes P450 in mouse: evidence for CYP2E1 induction in lung

Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure

Effect of CYP2E1 genetic polymorphisms on susceptibility of aplastic anemia

Effect of CYP2E1 induction by ethanol on the immunotoxicity and genotoxicity of extended low-level benzene exposure

Effect of CYP2E1 polymorphism on DNA stability and lung cancer susceptibility

Effect of CYP2E1 Ras I Genotypes on CYP2E1 Enzyme Activity and DNA Damage of Immortalized Human Lymphocytes Induced by Phenol

Effect of different radix polygoni multiflori preparata on CYP2E1 mRNA expression in rat liver [J]

Effect of disulfiram‐mediated CYP2E1 inhibition on the disposition of vesnarinone

Effect of Er Chen Tang on CYP2E1 and Mitochondrial Energy Metabolism in Nonalcoholic Fatty Liver Disease

Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis

Effect of exposure to benzo [a] pyrene on SODs, CYP1A1/1A2-and CYP2E1 immunopositive proteins in the blood clam

Effect of exposure to benzo [a] pyrene on SODs, CYP1A1/1A2-and CYP2E1 immunopositive proteins in the blood clam Scapharca inaequivalvis

Effect of fasting and obesity in humans on the 6‐hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity

Effect of flavonoids extract from apocynum venetum tea on CYP2E1 in mice.

Effect of Ganzheng formula on CYP2E1, adiponectin and TNF-α in NAFLD rats

Effect of Gegen Powder on CYP450 Content of Liver Microsomal and Activity of CYP2E1 in Mice Acute Alcohol-induced Liver Injury

Effect of genetic polymorphisms of toxin metabolic enzyme CYP2E1 on metabolism of styrene

Effect of high‐dose aspirin on CYP2E1 activity in healthy subjects measured using chlorzoxazone as a probe

Effect of jujube on the expression of CYP2E1 and TNF-alpha in the hepatic tissue of mice with alcoholic liver disease

Effect of Leflunomide on the content of cytochrome P450 enzyme and CYP2E1 mRNA expression of mice with acute chemical injury [J]

Effect of methacrylonitrile on cytochrome P-450 2E1 (CYP2E1) expression in male F344 rats

EFFECT OF NARINGIN ON THE ACTIVITY OF HUMAN LIVER MICROSOMES CYP2E1 USING PROBE DRUG METHOD

Effect of neferine on CYP450 total enzyme and CYP3A1, CYP2D1, CYP2E1 mRNA in Rats

Effect of oleanolic acid on CYP1A2, CYP2E1 and CYP3A4 activity in healthy subjects

Effect of piperine on CYP2E1 enzyme activity of chlorzoxazone in healthy volunteers

Effect of quercetin on CYP1A2, CYP2E1, CYP3A2 activities and its inhibitory mechanism studies in rat liver microsomes

Effect of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos before and after compatibility on activities of CYP1A2, CYP2E1, and CYP3A4 from rat liver …

Effect of Sanchi on expression of hepatic CYP2E1 in liver tissues in rats with alcoholic liver disease [J]

Effect of Seed Coat ofEuryale ferox Extract in Non-alcoholic Fatty Liver Disease Induced by High-fat Diet in Mice by Increasing IRs-1 and Inhibiting CYP2E1

Effect of starvation and acetone on the enzyme systems of biotransformation and toxicity of xenobiotics–CYP2E1 substrates in rats

Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression

Effect of Sulfamethoxazole, Glycyrrhiza Uralensis Fisc and Fisch Fructus Forsythiae on Cytochrome CYP2E1 in Paralichthys Olivaceus by Probe Drugs

Effect of sulfur dioxide inhalation on CYP2B1/2 and CYP2E1 in rat liver and lung

Effect of temperature on carp CYP2E1-like isoform activity.

Effect of TFHL on expression of CYP2E1 in liver tissue of rats with NASH.

Effect of the CYP2E1 genotype on vinyl chloride monomer-induced liver fibrosis among polyvinyl chloride workers

Effect of the South African traditional meat, biltong, on cancer-associated enzymes CYP2E1 and CYP1A2

EFFECT OF TOTAL ALKALOIDES OF ACONITUM EXCELSUM REICHB ON CYP2E1 METABOLISM ACTIVITY IN MORPHINE DEPENDENT RATS [J]

Effect of total alkaloids of Rubus alceaefolius poiron on gene expressions of CYP2E1 and CYP3A1 in rats with acute liver injury

Effect of water miscible organic solvents on p-nitrophenol hydroxylase (CYP2E1) activity in rat liver microsomes

Effect of XiaozhiHugan Capsule on Pathologic Changes and CYP2E1 Gene Expression of Rats with Non-alcoholic Fatty Liver [J]

Effect of γ-irradiation and mitomycin C (MMC) on CYP2B1 and CYP2E1 activities in rat hepatic microsomes in vitro

Effects of acrylamide on oxidant/antioxidant parameters and CYP2E1 expression in rat pancreatic endocrine cells

Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1, 3‐dimethyluric …

Effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on toluene metabolism in humans

Effects of aqueous extract of Polygoni Multiflori Radix and its main constituents on expression of mRNA of CYP1A2, CYP2C9, and CYP2E1 in human liver L02 cells

Effects of benzene on liver, kidney and lung cyp1a, cyp2b4, CYP2E1 and cyp3a6 mrna, protein level, and drug metabolizing enzyme activities and toxicity in diabetic …

Effects of blueberry on ultrastructural and expression of cytochrome CYP2E1 in rats with immune hepatic fibrosis

Effects of chlorinated aliphatic hydrocarbons on the fidelity of cell division in human CYP2E1 expressing cells

Effects of cytochrome P450 (CYP) 2A6 gene deletion and CYP2E1 genotypes on gastric adenocarcinoma

Effects of Danshen and Its Active Components on Rat CYP2E1 Expression and Metabolism of Model CYP2E1 Probe Substrate

Effects of diabetes on rabbit kidney and lung CYP2E1 and CYP2B4 expression and drug metabolism and potentiation of carcinogenic activity of N …

Effects of dietary fat composition on activities of the microsomal ethanol oxidizing system and ethanol‐inducible cytochrome P450 (CYP2E1) in the liver of rats …

Effects of Environmental Carcinogens and Genetic Polymorphisms of CYP2E1 and NAT2 on Gastric Carcinogenesis.

Effects of environmental factors on extrahepatic CYP2E1 gene expression in mice

Effects of ethanol on CYP2E1 levels and related oxidative stress using a standard balanced diet

Effects of flavonoids in Lysimachia clethroides duby on the activities of cytochrome P450 CYP2E1 and CYP3A4 in rat liver microsomes

Effects of Ganoderma lucidum polysaccharide on CYP2E1, CYP1A2 and CYP3A activities in BCG-immune hepatic injury in rats

Effects of Ganzhengfufang on the PPARγ and CYP2E1 in the rat with nonalcoholic fatty liver disease

Effects of genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 on the urinary levels of 1-hydroxypyrene and 2-naphthol in aircraft maintenance workers

Effects of GSTM1 and CYP2E1 Genetic Polymorphism and Drinking on DNA Damage among Workers Exposed to Phenol and Acetone

Effects of metadoxine on the expression of CYP2E1 in liver tissue of male rats with alcoholic fat liver [J]

Effects of mitomycin (MMC) and {gamma}-ray irradiation on cytochrome p450 content and activities of CYP2B1 and CYP2E1 in rats

Effects of mitomycin (MMC) and γ-ray irradiation on cytochome p450 content and activities of CYP2B1and CYP2E1 in rats [J]

Effects of mitomycin (MMC) and γ-ray irradiation on cytochrome p450 content and activities of CYP2B1 and CYP2E1 in rats

Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in …

Effects of nonyphenol exposure during pregnant and lactation period on expressions of CYP2E1 mRNA and protein of hepatic tissues in offspring rats

Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations

Effects of Purified Glycerol from Biodiesel on Cyp1a1 and CYP2E1 Expressions in CBA/CA Mice

Effects of rifampin on CYP2E1-dependent hepatotoxicity of isoniazid in rats

Effects of SNPs (CYP1B1* 2 G355T, CYP1B1* 3 C4326G, and CYP2E1* 5 G-1293C), smoking, and drinking on susceptibility to laryngeal cancer among Han …

Effects of steady-state lasofoxifene on CYP2D6-and CYP2E1-mediated metabolism

EFFECTS OF STRUCTURALLY AND FUNCTIONALLY DIVERSE GROUP OF PHYTOCHEMICALS ON ANILINE HYDROXYLATION (CYP2E1) OF CONTROL AND …

Effects of SU-MIAN-XIN on CYP3A1 and CYP2E1 in Rat Primary Cultured Hepatocytes

Effects of the activities and mRNA level of CYP2E1 in mouse liver microsomal by Folium Isatidis

Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue

Effects of the plant phenolic quercetin on protein and mRNA CYP1A1, CYP2E1, NQO1 and GST enzymes in colon cancer cell line SW620

Effects of Trichloroethylene Toxicity on Normal Human Liver Cells and Hepatocytes With CYP2E1 Gene Overexpression

Effects of Zhenyuan Capsule on Cytochrome P450 Enzymes CYP1A2, CYP3A4 and CYP2E1

Ekspresija CYP2E1 u testisima štakora i alkoholom prouzrokovane promjene indeksa spermatogeneze i kolagena tipa I

Elimination rate of 6-hydroxychlorzoxazone in urine as a non-invasive evaluation of cytochrome CYP2E1 activity. Lack of relationship to smoking

Elucidation of CYP2E1 5′ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer

End-product inhibition of skatole-metabolising enzymes CYP1A, CYP2A19 and CYP2E1 in porcine and piscine hepatic microsomes

Environmental exposure to benzene: evaluation of urinary S-PMA and polymorphism (CYP2E1-1293G> C and NQO1 609C> T) in Campos Elíseos residents …

‐en‐Y gastric bypass surgery influenced pharmacokinetics of several drugs given as a cocktail with the highest impact observed for CYP1A2, CYP2C8 and CYP2E1 …

Ephedra water decoction and cough tablets containing ephedra and liquorice induce CYP1A2 but not CYP2E1 hepatic enzymes in rats

Epididymal CYP2E1 plays a critical role in acrylamide-induced DNA damage in spermatozoa and paternally mediated embryonic resorptions

Epilobium hirsutum alters xenobiotic metabolizing CYP1A1, CYP2E1, NQO1 and GPx activities, mRNA and protein levels in rats

Epoxide formation from diallyl sulfone is associated with CYP2E1 inactivation in murine and human lungs

Establishment and toxicological application of a cell line expressing human CYP2E1

Establishment of a p-nitrophenol oxidation-based assay for the analysis of CYP2E1 activity in intact hepatocytes in vitro

Establishment of model with exogenous human CYP2E1 expression and inducement of substrates

Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol

Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1

Ethanol enhanced the genotoxicity of acrylamide in human, metabolically competent HepG2 cells by CYP2E1 induction and glutathione depletion

Ethanol induces CYP2E1 by protein stabilization role of ubiquitin conjugation in the rapid degradation of CYP2E1

Ethanol induction of CYP2A5: permissive role for CYP2E1

Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway

Ethanol self-administration and nicotine treatment induce brain levels of CYP2B6 and CYP2E1 in African green monkeys

Ethanol withdrawal induced CYP2E1 degradation in vivo, blocked by proteasomal inhibitor PS-341

Ethanol-induced oxidative DNA damage and CYP2E1 expression in liver tissue of Aldh2 knockout mice

Ethanol-induced oxidative stress is associated with EGF receptor phosphorylation in MCF-10A cells overexpressing CYP2E1

Ethanol‐induced oxidative stress via the CYP2E1 pathway disrupts adiponectin secretion from adipocytes

Ethanol-induction of cytochrome P450 2A5: permissive role for CYP2E1

Ethanol‐mediated carcinogenesis in the human esophagus implicates CYP2E1 induction and the generation of carcinogenic DNA‐lesions

Ethanol-mediated transplacental induction of CYP2E1 in fetal rat liver

Ethanol‐related cytotoxicity catalyzed by CYP2E1‐dependent generation of reactive oxygen intermediates in transduced HepG2 cells

Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations

Evaluation of activity of hepatic CYP2E1 following administration of Radix et Rhizoma Rhei by probe drug in rats [J]

Evaluation of caffeine as a test drug for CYP1A2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations

Evaluation of influence of Andrographis paniculata on activities of CYP1A2, CYP3A4, CYP2E1 and CYP2C19 genotypes in chickens by multiple cytochrome P450 …

Evidence for a tissue-specific induction of cutaneous CYP2E1 by dexamethasone

Evidence for the Existence of Two Human CYP2E1 cDNAs Using Different Polyadenylation Signals

Evidence of association of the CYP2E1 genetic polymorphism with micronuclei frequency in human peripheral blood

Evolution of camel CYP2E1 and its associated power of binding toxic industrial chemicals and drugs

Exacerbation of benzene pneumotoxicity in connexin 32 knockout mice: enhanced proliferation of CYP2E1-immunoreactive alveolar epithelial cells

Examination of a CYP2E1 repeat polymorphism in a monkey model of alcohol abuse

Experimental study on effect of Erchen decoction and Taohongsiwu decoction on CYP2E1 activities in non-alcoholic fatty liver rats

Experimental study on the effects of combined administration of Shuanghuanglian powder for injection and levofloxacin hydrochloride injection on CYP2E1 in mice

exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 …

Expression and activity of CYP2E1 in circulating lymphocytes are not altered in diabetic individuals

Expression and regulation of cytochrome P450 CYP2E1 in the minipig

Expression of CYP2E1 by human monocyte‐derived macrophages

Expression of CYP2E1 during human fetal development: methylation of the CYP2E1 gene in human fetal and adult liver samples

Expression of CYP2E1 gene in liver tissue in patients with hepatic cirrhosis and obstuctive jaundice

Expression of CYP2E1 gene in paint workers occupationally exposed to organic solvents

Expression of CYP2E1 in Human Lung and Kidney during Development and in Full‐Term Placenta: A Differential Methylation of the Gene is Involved in the …

Expression of CYP2E1 in human nasopharynx and its metabolic effect in vitro

Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice

Expression of cytochrome P450 enzymes CYP1A1, CYP1B1, CYP2E1 and CYP4B1 in cultured transitional cells from specimens of the human urinary tract and from …

Expression of human CYP2E1 in insect cells using bac-to-bac expression system

Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous system

Extrahepatic metabolism by CYP2E1 in PBPK modeling of lipophilic volatile organic chemicals: impacts on metabolic parameter estimation and prediction of dose …

Fast CYP2E1 genotyping using automated fluorescent detection.

Featured structure-activity relationships for some tri-and tetrachlorobiphenyls in human CYP2E1-activated mutagenicity—Impact of the extent of ortho-chlorination

Ferric citrate CYP2E1-independently promotes alcohol-induced apoptosis in HepG2 cells via oxidative/nitrative stress which is attenuated by pretreatment with …

final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: role of CYP2E1 and Keap1-Nrf2 …

for the Expression of Recombinant Human Cytochrome P450s inEscherichia coliUsing Bacterial Signal Peptides: Expression of CYP3A4, CYP2A6, and CYP2E1

Formation of multiple CYP2E1 complexes affects activity

Frequencies of genotypes and alleles of the functional SNPs in CYP2C19 and CYP2E1 in mainland Chinese Kazakh, Uygur and Han populations

Frequency distribution of high risk alleles of CYP2C19, CYP2E1, CYP3A4 genes in Haryana population

Functional analyses of the pig CYP2E1 promoter and identification of the transcription factors required for CYP2E1 expression

Functional CYP2E1 is required for substantial in vivo formation of 2,5-hexanedione from n-hexane in the mouse

Functional polymorphism in porcine CYP2E1 gene: Its association with skatole levels

Functional polymorphism of CYP2E1 gene and alcohol use disorders in a Tibetan population.

Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1

Garlic oil alleviated ethanol-induced fat accumulation via modulation of SREBP-1, PPAR-α, and CYP2E1

Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1

Gene CYP2E1 expression in mouse liver cells exposed to low-dose radiation

Gene Structure and Multiple Regulations of the Ethanol-Inducible Cytochrome P45O2E1 (CYP2E1) Subfamily

Gene–environmental interactions between alcohol-drinking behavior and ALDH2 and CYP2E1 polymorphisms and their impact on micronuclei frequency in human …

Genetic and dietary predictors of CYP2E1 activity: a phenotyping study in Hawaii Japanese using chlorzoxazone

Genetic Interaction between NAT2, GSTM1, GSTT1, CYP2E1, and Environmental Factors Is Associated with Adverse Reactions to Anti-Tuberculosis Drugs

Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in a Chinese Tibetan population

Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in Chinese Han populations from four different geographic areas of Mainland China

Genetic polymorphism in CYP2E1: Population distribution of CYP2E1 activity

Genetic Polymorphism in Promoter Sequence of CYP2E1 Gene in Paint Manufacturing Workers Exposed to Volatile Organic Compounds

Genetic polymorphism of CYP2D6, CYP2E1 and susceptibility to chronic occupational manganism poisoning [J]

Genetic polymorphism of CYP2E1 and digestive tract alcohol damage among Polish individuals

Genetic polymorphism of CYP2E1, ADH2, and ALDH2 in Mexican-Americans

Genetic polymorphism of cytochrome P450 (CYP) 1A1, CYP1A2, and CYP2E1 genes modulate susceptibility to gastric cancer in patients with Helicobacter …

Genetic polymorphism of GSTM1, CYP2E1 and CYP2D6 in Egyptian bladder cancer patients

Genetic polymorphism of human CYP2E1: characterization of two variant alleles

Genetic polymorphism of human CYP2E1: new allels detected in exons and exon-intron junctions

Genetic polymorphism of the CYP1A1, CYP2E1, GSTM1 and GSTT1 genes and lung cancer susceptibility in a north Indian population

Genetic polymorphism of the CYP2E1 gene and susceptibility to Parkinson’s disease in Taiwanese

Genetic polymorphisms in CYP2E1: association with schizophrenia susceptibility and risperidone response in the Chinese Han population

Genetic polymorphisms in cytochrome P450 (CYP) 1A1, CYP1A2, CYP2E1, glutathione S-transferase (GST) M1 and GSTT1 and susceptibility to prostate cancer in the …

Genetic polymorphisms in GSTM1,-P1,-T1, and CYP2E1 and the risk of adult brain tumors

Genetic Polymorphisms of ADH1C and CYP2E1 and Risk of Oral Squamous Cell Carcinoma

Genetic polymorphisms of alcohol inducible CYP2E1 in Turkish population

Genetic Polymorphisms of CYP1A1, CYP2E1, and GSTM1 Genes: Susceptibility to Colon Cancer

Genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 associated with head and neck cancer

Genetic polymorphisms of CYP2D6, CYP1A1 and CYP2E1 in the South-Amerindian population of Chile.

Genetic polymorphisms of CYP2E1 and DNA repair genes HOGG1 and XRCC1: association with hepatitis B related advanced liver disease and cancer

Genetic polymorphisms of CYP2E1 and GSTM1 and T1 on susceptibility to esophageal cancer in Huaian, China

Genetic polymorphisms of CYP2E1 and GSTM1 loci and susceptibility to anti-tuberculosis drug-induced hepatotoxicity

Genetic polymorphisms of CYP2E1 and risk of colorectal adenomas in the Self Defense Forces Health Study

Genetic polymorphisms of CYP2E1 and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study

Genetic polymorphisms of CYP2E1, GST, and NAT2 enzymes are not associated with risk of breast cancer in a sample of Lebanese women

Genetic polymorphisms of CYP2E1, GSTM1, and GSTT1; environmental factors and risk of oral cancer.

Genetic polymorphisms of CYP2E1, GSTT1, GSTP1, GSTM1, ALDH2, and ODC and the risk of advanced precancerous gastric lesions in a Chinese population

Genetic Polymorphisms of Genes Coding to Alcohol‐Metabolizing Enzymes in Western Mexicans: Association of CYP2E1*c2/CYP2E1*5B Allele with Cirrhosis and …

Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis

Genetic Polymorphisms of NAT2, CYP2C9, CYP2C19, CYP2D6 and CYP2E1, and Antituberculosis Drugs Induced Maculopapular Eruption

Genetic polymorphisms of NAT2, CYP2E1 and GST enzymes and the occurrence of antituberculosis drug-induced hepatitis in Brazilian TB patients

Genetic Polymorphisms of SLCO1B1, CYP2E1 and UGT1A1 and Susceptibility to Anti-Tuberculosis Drug-Induced Hepatotoxicity: A Chinese Population-Based …

Genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fishes Poeciliopsis occidentalis and Poeciliopsis lucida

Genetic Repeat Polymorphism in the Regulating Region of CYP2E1: Frequency and Relationship With Enzymatic Activity in Alcoholics

Genetic Variability in CYP2E1 and Catalase Gene Among Currently and Formerly Alcohol-Dependent Male Subjects

Genetic variants of ALDH2-rs671 and CYP2E1-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population

Genetic variation in the temperature dependence of liver microsomal CYP2E1 activity, within and between species of the viviparous fish Poeciliopsis

Genetic variations of NAT2 and CYP2E1 and isoniazid hepatotoxicity in a diverse population

Genotoxicity of 1‐methylpyrene and 1‐hydroxymethylpyrene in chinese hamster V79‐derived cells expressing both human CYP2E1 and SULT1A1

Genotype and allele frequencies of polymorphic CYP2E1 in the Turkish population

Genotype and allele frequencies of polymorphic cytochromes P450 CYP1A2 and CYP2E1 in Mexicans

Genotype and allelic frequencies of CYP2E1* 5B polymorphism in the southwest population of Iran

Genotype and phenotype polymorphisms of NAT2 and CYP2E1 in the Han Chinese pediatric population

Genotype Polymorphisms of NAT2 and CYP2E1 Genes Associated with Drug Induced Liver Injury (DILI) in Indonesian Tuberculosis Patients

Global Analysis of Protein− Protein Interactions Reveals Multiple CYP2E1− Reductase Complexes

Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene

Glucose inhibition of the induction of CYP2E1 mRNA expression by ethanol in FGC-4 cells

Glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2

Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-κB …

Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice

Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity

Growth retardation of fetal rats exposed to nicotine in utero: Possible involvement of CYP1A1, CYP2E1, and P‐glycoprotein

GSTT1 and CYP2E1 polymorphisms and trihalomethanes in drinking water: effect on childhood leukemia.

GSTT1, GSTM1 and CYP2E1 genetic polymorphisms in gastric cancer and chronic gastritis in a Brazilian population

GYKI-47261, a new AMPA [2-amino-3-(3-hydroxymethylisoxazole-4-yl) propionic acid] antagonist, is a CYP2E1 inducer

Halothane inhalation inhibits the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits

HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma cells

Helicobacter pylori infection, but not genetic polymorphism of CYP2E1, is highly prevalent in gastric cancer patients younger than 40 years

Hepatic and pulmonary microsomal benzene metabolism in CYP2E1 knockout mice

Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling

Hepatoprotective effect of 10% ethanolic extract from Curdrania tricuspidata leaves against ethanol-induced oxidative stress through suppression of CYP2E1

Hepatoprotective Effect of Punica granatum Seed Oil Extract on Paracetamol Intoxication in Rat Via Inhibory Effect of CYP2E1

Hepatotoxicity Mediated by Pyrazole (CYP2E1) Plus TNF-α Treatment Occurs in jnk2−/− but not in jnk1−/− Mice

Heteromeric complex formation between CYP2E1 and CYP1A2: evidence for the involvement of electrostatic interactions

High CYP2E1 activity aggravates hepatofibrosis by limiting macrophage polarization towards the M2 phenotype

High CYP2E1 activity correlates with hepatofibrogenesis induced by nitrosamines

High dose lycopene supplementation increases hepatic CYP2E1 protein and TNF‐α expression in alcohol fed rats

High inducibility of mouse renal CYP2E1 gene by tobacco smoke and its possible effect on DNA single strand breaks

Higher sensitivity of female cells to ethanol: methylation of DNA lowers CYP2E1, generating more ROS

Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells overexpressing CYP2E1

Histone modification-mediated CYP2E1 gene expression and apoptosis of HepG2 cells

Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions

Hormone controlled phosphorylation and degradation of CYP2B1 and CYP2E1 in isolated rat hepatocytes

How mutations affecting the ligand-receptor interactions: a combined MD and QM/MM calculation on CYP2E1 and its two mutants

Human CYP2A6, CYP2B6, and CYP2E1 atropselectively metabolize polychlorinated biphenyls to hydroxylated metabolites

Human CYP2E1 is regulated by miR-378

Human CYP2E1 mediates the formation of glycidamide from acrylamide

Human CYP2E1-activated mutagenicity of dioxin-like PCBs 105 and 118—Experimental data consistent with molecular docking results

Human CYP2E1-dependent and human sulfotransferase 1A1-modulated induction of micronuclei by benzene and its hydroxylated metabolites in Chinese hamster …

Human CYP2E1‐dependent mutagenicity of benzene and its hydroxylated metabolites in V79‐derived cells: Suppression and enhancement by ethanol pretreatment

Human CYP2E1-dependent mutagenicity of mono-and dichlorobiphenyls in Chinese hamster (V79)-derived cells

Human cytochrome P450 2E1 (CYP2E1): from genotype to phenotype.

Human hepatic CYP2E1 expression during development

Human hepatocytes are protected from ethanol-induced cytotoxicity by DADS via CYP2E1 inhibition

Human placental lactogen induces CYP2E1 expression via PI 3-kinase pathway in female human hepatocytes

Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation)

Hypomethylation and hypoexpression of human CYP2E1 gene in lung tumors

Identification and characterization of a mitochondrial targeting signal in rat cytochrome P450 2E1 (CYP2E1)

Identification and functional analysis of a novel human CYP2E1 far upstream enhancer

Identification of 2-piperidone as a biomarker of CYP2E1 activity through metabolomic phenotyping

Identification of a 16-nucleotide sequence that mediates post-transcriptional regulation of rat CYP2E1 by insulin

Identification of a critical CYP2E1 epitope in patients with drug-induced liver injury from anesthetics (93.16)

Identification of CYP2E1 in marmoset monkey

Identification of CYP2E1-dependent genes involved in carbon tetrachloride-induced hepatotoxicity

Identification of cytochrome CYP2E1 as critical mediator of alcohol effects on steatotic hepatocytes

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

Identification of deletions and duplications in the CYP2E1 gene in a population in Goiânia–GO by MLPA.

Identification of inhibitory component in cinnamon—o-methoxycinnamaldehyde inhibits cyp1a2 and CYP2E1—

Identification of Novel CYP2E1 Inhibitor to Investigate Cellular and Exosomal CYP2E1-Mediated Toxicity

Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and CYP2E1-null …

Identification of sequences responsible for intracellular targeting and membrane binding of rat CYP2E1 in yeast

IL-4 promotes experimental drug-induced hepatitis by reducing immune responses to haptenated proteins and inhibiting regulatory responses to native CYP2E1 …

IL-4-mediated transcriptional regulation of human CYP2E1 by two independent signaling pathways

Immunohistochemical demonstration of the expression of CYP2E1 in human breast tumour and non-tumour tissues

Immunohistochemical Detection of CYP2E1 and 2-S-Glutathionyl Acetate in Murine Lung Tumors: Diminished Formation of Reactive Intermediates of 1,1 …

Immunohistochemical study of CYP2E1 in hepatocellular carcinoma carcinogenesis: examination with newly prepared anti-human CYP2E1 antibody

Immunological detection of CYP2E1 in fresh rat lymphocytes and its pretranslational induction by fasting

Impact of CYP2E1 genotype in renal cell and urothelial cancer patients

Impact of CYP2E1 polymorphisms on the risk of esophageal cancer

Impact of CYP2E1, GSTA1 and GSTP1 gene variants on serum alpha glutathione S-transferase level in patients undergoing anaesthesia

Impairment of Akt activity by CYP2E1 mediated oxidative stress is involved in chronic ethanol-induced fatty liver

Implication of xenobiotic metabolizing enzyme gene (CYP2E1, CYP2C19, CYP2D6, mEH and NAT2) polymorphisms in breast carcinoma

in rats induced by aqueous extract of Polygoni Multiflori Radix, root of Polygonum multiflorum related to the activity inhibition of CYP1A2 or CYP2E1

in urea in conjunction with L-arginine metabolism in the liver leads to induction of cytochrome P450 2E1 (CYP2E1): The role of urea in CYP2E1 induction by acute …

In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV …

In vitro inhibition of human CYP2E1 and CYP3A by quercetin and myricetin in hepatic microsomes is not gender dependent

In vitro metabolism of styrene to styrene oxide in liver and lung of CYP2E1 knockout mice

In vivo and in vitro characterization of chlorzoxazone metabolism and hepatic CYP2E1 levels in African Green monkeys: induction by chronic nicotine treatment

In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians.

In vivo CYP2E1 phenotyping as a new potential biomarker of occupational and experimental exposure to benzene

Inactivation of cytochrome P-450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes by vinyl carbamate in murine pulmonary microsomes

Inactivation of hepatic CYP2E1 by an epoxide of diallyl sulfone

Inactivation of stress protein p8 increases murine carbon tetrachloride hepatotoxicity via preserved CYP2E1 activity

Increase expression of CYP2E1 mRNA after methamphetamine administration in rats

Increased bioaccumulation of urethane in CYP2E1-/-versus CYP2E1+/+ mice

Increased Expression of CYP2E1 gene in gastric cancer may be a molecular marker for mazandaran province population

Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation

Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co‐expressing HCV core protein and CYP2E1

Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1

Independent and combined effects of ethanol self-administration and nicotine treatment on hepatic CYP2E1 in African green monkeys

Individual variability of CYP2E1 xenobiotic oxidation in human liver

Induction and recovery time course of rat brain CYP2E1 after nicotine treatment

Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration.

Induction of brain CYP2E1 by chronic ethanol treatment and related oxidative stress in hippocampus, cerebellum, and brainstem

Induction of brain CYP2E1 changes the effects of ethanol on dopamine release in nucleus accumbens shell

Induction of catalase, alpha, and microsomal glutathione S‐transferase in CYP2E1 overexpressing HepG2 cells and protection against short‐term oxidative stress

Induction of CYP1A1 and CYP2E1 in rat liver by histamine: binding and kinetic studies

Induction of CYP2B and CYP2E1 in precision-cut rat liver slices cultured in defined medium

Induction of CYP2E1 activity in Ctenopharyngodon idellus hepatocyte

Induction of CYP2E1 activity in liver transplant patients as measured by chlorzoxazone 6‐hydroxylation

Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: evidence that CYP2E1 possesses a rapid phase half …

Induction of CYP2E1 in non-alcoholic fatty liver diseases

Induction of CYP2E1 in testes of isoniazid-treated rats as possible cause of testicular disorders

Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression

Induction of hepatic CYP2E1 by a subtoxic dose of acetaminophen in rats: increase in dichloromethane metabolism and carboxyhemoglobin elevation

Induction of nicotine-metabolizing CYP2B1 by ethanol and ethanol-metabolizing CYP2E1 by nicotine: summary and implications

Induction of rat hepatic CYP2E1 expression by arecoline in vivo

Induction of SIRT1 by melatonin improves alcohol‐mediated oxidative liver injury by disrupting the CRBN‐YY1‐CYP2E1 signaling pathway

Influence of Acarbose, Metformin and Pioglitazone on TNF-αand CYP2E1 in Liver Tissue of NAFLD Rat

Influence of CYP1A1, CYP2E1, GSTM3 and NAT2 genetic polymorphisms in oral cancer susceptibility: results from a case-control study in Rio de Janeiro

INFLUENCE OF GENETIC ADMIXTURE ON POLYMORPHISMS OF ALCOHOL-METABOLIZING ENZYMES: ANALYSES OF MUTATIONS ON THE CYP2E1, ADH2, ADH3 AND …

Influence of genetic admixture on polymorphisms of drug‐metabolizing enzymes: Analyses of mutations on NAT2 and CYP2E1 genes in a mixed Hispanic …

Influence of GSTs, CYP2E1 and mEH polymorphisms on 1, 3-butadiene-induced micronucleus frequency in Chinese workers

Influence of GSTT1, mEH, CYP2E1 and RAD51 polymorphisms on diepoxybutane-induced SCE frequency in cultured human lymphocytes

Influence of NQO1, ALDH2, and CYP2E1 genetic polymorphisms, smoking, and alcohol drinking on the risk of lung cancer in Koreans

Influence of selected inhibitors on the metabolism of the styrene metabolite 4-vinylphenol in wild-type and CYP2E1 knockout mice

Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and …

Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single ingestion of watercress

Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single-dose watercress ingestion; comparison with one week isoniazid treatment

Inhibition of CYP2E1 activity does not abolish pulsatile urine alcohol concentrations during chronic alcohol infusions

Inhibition of CYP2E1 and activation of Nrf2 signaling pathways by a fraction from Entada africana alleviate carbon tetrachloride-induced hepatotoxicity

Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis

Inhibition of CYP2E1 attenuates myocardial dysfunction in a murine model of insulin resistance through NLRP3-mediated regulation of mitophagy

Inhibition of CYP2E1 by chlormethiazole as measured by chlorzoxazone pharmacokinetics in patients with alcoholism and in healthy volunteers

Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine

Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 over-expressing VL-17A cells

Inhibition of CYP2E1 leads to decreased malondialdehyde–acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure

Inhibition of CYP2E1 Reverses CD4+ T-Cell Alterations in Trichloroethylene-Treated MRL+/+ Mice

Inhibition of CYP2E1 with natural agents may be a feasible strategy for minimizing the hepatotoxicity of ethanol

Inhibition of CYP2E1 With Propylene Glycol Does Not Protect Against Hepatocellular Injury in Human Acetaminophen Daily‐Dosing Model

Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components

Inhibition of cytochrome P450 enzymes participating in p-nitrophenol hydroxylation by drugs known as CYP2E1 inhibitors

Inhibition of Ethanol-induced CYP2E1 by Curcuma longa L. Extract

Inhibition of rat hepatic CYP2E1 by quinacrine: molecular modeling investigation and effects on 4-(methyl nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced …

Inhibition of Urethane-Induced Carcinogenicity in CYP2E1−/− in Comparison to CYP2E1+/+ Mice

Inhibition of Urethane-Induced Carcinogenicity in CYP2E1-/-Vs. CYP2E1+/+ Mice

Inhibition of urethane-induced genotoxicity and cell proliferation in CYP2E1-null mice

Inhibitory effects of cytochrome P450 enzymes CYP1A2, CYP2A6, CYP2E1 and CYP3A4 by extracts and alkaloids of Gelsemium elegans roots

Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity

Insertion polymorphism of CYP2E1 and urinary N -methylformamide after N,N - dimethylformamide exposure in Japanese workers

Insertion Polymorphism of the CYP2E1 Gene in Patients with Infiltrative Pulmonary Tuberculosis from Bashkortostan

Insertional polymorphism of the CYP2E1 gene in infiltrative pulmonary tuberculosis in populations of Bashkortostan Republic

Insights into insulin-mediated regulation of CYP2E1: miR 132/212 targeting of CYP2E1 and role of PI3-K, Akt, mTOR signaling in regulating miR132/212 and miR 122 …

Insights into insulin-mediated regulation of CYP2E1: miR-132/-212 targeting of CYP2E1 and role of phosphatidylinositol 3-kinase, Akt (protein kinase B), mammalian …

Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes

Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression

Interaction between genetic polymorphisms of CYP2E1 & NAT1 and smoking in lung cancer development (Preliminary report)

Interaction between Polymorphisms in CYP2E1 Rsa Ⅰ Genotypes and Lifestyle with Risk of Stomach Cancer

Interaction of polymorphisms of CYP2E1 and environmental risk factors in gastric cancer

Interactions between CYP2E1 and CYP2B4: effects on affinity for NADPH-cytochrome P450 reductase and substrate metabolism

Interactions between CYP2E1, GSTZ1 and GSTT1 polymorphisms and exposure to drinking water trihalomethanes and their association with semen quality

Interindividual variability of chlorzoxazone 6‐hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms

Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3

Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness

Investigation of bioactivation and toxicity of styrene in CYP2E1 transgenic cells

Investigation of indazole unbinding pathways in CYP2E1 by molecular dynamics simulations

Investigation of the inhibition of eight major human cytochrome P450 isozymes by a probe substrate cocktail in vitro with emphasis on CYP2E1

Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using CYP2E1-/-mice

In-Vitro CYP3A4, CYP2E1 and UGT Activity in Human Liver Microsomes by Strobilanthes crispus Leaf Extracts

Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes

Involvement of CYP2E1 as a low-affinity enzyme in phenacetin O-deethylation in human liver microsomes

Involvement of CYP2E1 in the course of brain edema induced by subacute poisoning with 1, 2-Dichloroethane in mice

Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism

Iron and CYP2E1-dependent oxidative stress and toxicity

Isolation of the mouse cytochrome P450J (CYP2E1) cDNA and its reciprocal testosterone regulation in kidney and liver

Isozyme-selective metabolism of ethyl carbamate by cytochrome P450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes in murine liver microsomes

Kaempferol’s protective effect on ethanol-induced mouse primary hepatocytes injury involved in the synchronous inhibition of SP1, Hsp70 and CYP2E1

Kinetic characterization of CYP2E1 inhibition in vivo and in vitro by the chloroethylenes

Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors

Kupffer cell inactivation alleviates ethanol-induced steatosis and CYP2E1 induction but not inflammatory responses in rat liver

Lack of association of CYP2E1 and CYP1A1 polymorphisms with osteoporosis in postmenauposal women

Lack of common mutation in the alfa-subunit of the mitochondrial trifunctional protein and the polymorphism of CYP2E1 in three Japanese women with acute fatty liver …

Lack of correlation between lymphocytic mrna expression and activity of CYP3A4 and CYP2E1 In‐vivo in alcoholics and non‐alcoholics

Lack of cytochrome P450 2E1 (CYP2E1) induction in the rat liver by starvation without coprophagy

Lipid peroxidation, CYP2E1 and arachidonic acid metabolism in alcoholic liver disease in rats

Lipopolysaccharide induces CYP2E1 in astrocytes through MAP kinase kinase-3 and C/EBPβ and-δ

Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole

Liver cancer-related gene CYP2E1 expression in HBV transgenic mice with acute liver injury

Liver nuclear and microsomal CYP2E1-mediated metabolism of xenobiotics in rats chronically drinking an alcohol-containing liquid diet

Losartan effects on liver cytochromes CYP3A, CYP2C and CYP2E1 functioning at metabolic syndrome in young and adult rats

Loss of CYP2E1 and CYP1A2 activity as a function of acetaminophen dose: relation to toxicity

Low doses of curcumin protect alcohol-induced liver damage by modulation of the alcohol metabolic pathway, CYP2E1 and AMPK

Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver

Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1, 3-dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat

Lung cancer risk in relation to the CYP2E1 Rsa I genetic polymorphism among African-Americans and Caucasians in Los Angeles County.

Lycopene attenuates alcoholic apoptosis in HepG2 cells expressing CYP2E1

Lycopene attenuates arachidonic acid toxicity in HepG2 cells overexpressing CYP2E1

Lymphocyte cytochrome P450-CYP2E1 expression in human IDDM subjects

M1 Polarization bias and subsequent NASH progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1 induced oxidative stress in …

Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro

Malotilate, a hepatoprotectant, suppresses CYP2E1 expression in rats

Mammalian CYP2E1 gene triggered changes of relative ions fluxes, CaM content and genes expression profiles in Petunia hybrida cells to enhance resistance to …

Mammalian cytochrome CYP2E1 triggered differential gene regulation in response to trichloroethylene (TCE) in a transgenic poplar

Mannan‐binding lectin attenuates acetaminophen‐induced hepatotoxicity by regulating CYP2E1 expression via ROS‐dependent JNK/SP1 pathway

Maternal protein restriction during lactation modulated the expression and activity of rat offspring hepatic CYP1A1, CYP1A2, CYP2B1, CYP2B2, and CYP2E1 …

MATERNAL SMOKING, POLYMORPHISMS IN CYP1A1, CYP2E1, EPHX1, NAT2, NQO1, AND CHILDHOOD ACUTE LEUKEMIA

Mechanism and clinical significance of HBx-mediated inhibition of CYP2E1 expression in the human HepG2 hepatoma cell line

mechanism of Wu-Zi-Yan-Zong-Wan, a traditional Chinese herbal formula, against alcohol-induced oxidative damage in CYP2E1 cDNA-transfected HepG2 (E47) …

Mechanism-based inactivation of human CYP2E1 by diethyldithocarbamate

Mechanisms of down-regulation of CYP2E1 expression by inflammatory cytokines in rat hepatoma cells

Meta-analysis of CYP2E1 polymorphisms in liver carcinogenesis

Meta-analysis on the relationship between CYP2E1 genetic polymorphism and susceptibility to hepatocellular carcinoma in Chinese

Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia

Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1

Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH …

Metabolic activation of o-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1

Metabolic activities of cytochrome P-450 CYP2E1 and cytochrome P-450 CYP3A in hepatic alcohol-injuried rats [J]

Metabolic oxidation and toxification of N-methylformamide catalyzed by the cytochrome P450 isoenzyme CYP2E1.

Metabolism and toxicity of the styrene metabolite 4-vinylphenol in CYP2E1 knockout mice

Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression

Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo

Metabolism of ethyl carbamate by pulmonary cytochrome P450 and carboxylesterase isozymes: involvement of CYP2E1 and hydrolase A

Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity

Method for in vivo and in vitro Evaluation of CYP2E1 Activities

Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction

MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity

MicroRNA‐122 protects mice and human hepatocytes from acetaminophen toxicity by regulating CYP1A2 and CYP2E1 expression

Microsomal ethanol oxidizing system: transcriptional and posttranscriptional regulation of cytochrome P450, CYP2E1.

Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen

Mitochondrial dysfunction by γ-irradiation accompanies the induction of cytochrome P450 2E1 (CYP2E1) in rat liver

Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene

Modification effects of GSTM1, GSTT1 and CYP2E1 polymorphisms on associations between raw salted food and incomplete intestinal metaplasia in a high‐risk …

Modification of CYP2E1 and CYP3A4 activities in haemoglobin E-beta thalassemia patients

Modulation of CYP2E1 metabolic activity in a cohort of confirmed caffeine ingesting pregnant women with preterm offspring

Modulation of ethanol-mediated CYP2E1 induction by clofibrate and L-carnitine in rat liver

Modulation of mouse P450 isoforms CYP1A2, CYP2B10, CYP2E1, and CYP3A by the environmental chemicals mirex, 2, 2-bis (p-chlorophenyl)-1, 1-dichloroethylene …

Modulation of mRNA expression and activities of xenobiotic metabolizing enzymes, CYP1A1, CYP1A2, CYP2E1, GPx and GSTP1 by the Salicornia freitagii extract in …

Molecular cloning and sequence analysis of hamster CYP2E1

Molecular dynamics simulations of CYP2E1

Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1

Molecular modelling of CYP2E1 enzymes from rat, mouse and man: an explanation for species differences in butadiene metabolism and potential carcinogenicity, and …

Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the …

Morbidly obese patients exhibit increased CYP2E1-mediated oxidation of acetaminophen

mRNA Expression of CYP2E1, CYP2A19, CYP1A2, HSD3B, SULT1A1 and SULT2A1 genes in surgically castrated, immunologically castrated, entire male and female …

Multifold Activation of CYP3A4 Caused by Alcohol-Induced Increase in the Content of CYP2E1 in Human Liver Microsomes

Mutagenic Activity of N‐Nitrosodiethylamine in Cell Lines Expressing Human CYP2E1—Adequacy of Dimethylsulfoxide as Solvent

NADPH: CYTOCHROME P450 REDUCTASES OF VARIOUS SPECIES CAN BE USED IN SYSTEMS RECONSTITUTING DRUG-METABOLIZING CYP2E1 …

NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species

Nanoformulated SOD1 ameliorates the combined NASH and alcohol-associated liver disease partly via regulating CYP2E1 expression in adipose tissue and liver

NAT2 and CYP2E1 polymorphisms and susceptibility to first-line anti-tuberculosis drug-induced hepatitis

NAT2, CYP2C9, CYP2C19, and CYP2E1 genetic polymorphisms in anti-TB drug-induced maculopapular eruption

NF-κB-mediated regulation of rat CYP2E1 by two independent signaling pathways

N-Hydroxylation of 4-Aminobiphenyl by CYP2E1 Produces Oxidative Stress in a Mouse Model of Chemically Induced Liver Cancer

Nicotinamide N-oxidation by CYP2E1 in human liver microsomes

Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity

No association between polymorphisms in CYP2E1, GSTM1, NAT1, NAT2 and the risk of gastric adenocarcinoma in the European prospective investigation into …

No association of CYP2E1 genetic polymorphisms with alcohol dependence in Han Taiwanese population

No linkage of the cytochrome P-450IIE1 (CYP2E1) C1/C2 polymorphism to schizophrenia

No significant expression of CYP2E1 in rat liver stellate cells

Non-additive effects of changing the cytochrome P450 ensemble: incorporation of CYP2E1 into human liver microsomes and its impact on CYP1A2

Noninvolvement of CYP2E1 in the (ω-1)-hydroxylation of fatty acids in rat kidney microsomes

Non-positive autoimmune responses against CYP2E1 in refrigeration mechanics exposed to halogenated hydrocarbons

Note of clarification of data on the association between CYP2E1 RsaI polymorphism and lung cancer risk

Novel CYP2E1 haplotype identified in a South African cohort

NQO1, MPO, CYP2E1, GSTT1 and GSTM1 polymorphisms and biological effects of benzene exposure—a literature review

Nrf2 and antioxidant defense against CYP2E1 toxicity

Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1

Obesity‐induced CYP2E1 activity in children

Obesity-induced increase of CYP2E1 activity and its effect on disposition kinetics of chlorzoxazone in Zucker rats

of human prenatal biosynthesis of all-trans-retinoic acid by ethanol, ethanol metabolites, and products of lipid peroxidation reactions: a possible role for CYP2E1

of liver microsomal 7-ethoxycoumarin O-deethylation and chlorzoxazone 6-hydroxylation activities in Japanese and Caucasian subjects genotyped for CYP2E1 …

of the accumulation of acetaldehyde from ethanol in human prenatal cephalic tissues: evaluation of the relative contributions of CYP2E1, alcohol dehydrogenase, and …

OF THE PLANT PHENOLIC QUERCETIN ON PROTEIN AND mRNA EXPRESSIONS OF XENOBIOTIC METABOLIZING CYP1A1, CYP2E1, NQO1 AND GST …

of twelve chlorinated aliphatic hydrocarbons upon the cell cycle of Chinese hamster cell lines: V79d-MZ and genetically engineered cell lines expressing CYP2E1

Ontogeny of hepatic CYP1A2 and CYP2E1 expression in rat

Ontogeny of rat CYP2E1 and CYP1A2: a characterization and a pharmacokinetic model

Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells

Opposite effects of isoniazid and fasting on the expression of CYP2E1 protein and mRNA in house musk shrew (Suncus murinus)

Oral clefts, maternal exposure to solvents and CYP2E1 polymorphism

overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1

Overexpression of CYP2E1 enhances sensitivity of hepG2 cells to fas-mediated cytotoxicity

Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione

Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5′-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR)

Over-expression of CYP2E1 mRNA and protein: implications of xenobiotic induced damage in patients with de novo acute myeloid leukemia with inv (16)(p13. 1q22); …

Oxidative stress caused by a SOD1 deficiency ameliorates thioacetamide-triggered cell death via CYP2E1 inhibition but stimulates liver steatosis

Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1

Oxidative stress potentiated by diallylsulfide, a selective CYP2E1 inhibitor, in isoniazid toxic effect on rat primary hepatocytes

Oxidative stress, toxicology, and pharmacology of CYP2E1

p53 mutation spectrum in relation to GSTM1, CYP1A1 and CYP2E1 in surgically treated patients with non-small cell lung cancer.

Panax vietnamensis protects mice against carbon tetrachloride-induced hepatotoxicity without any modification of CYP2E1 gene expression

patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, CYP2E1, gstm1 and gstt1

Persimmon vinegar and its fractions protect against alcohol-induced hepatic injury in rats through the suppression of CYP2E1 expression

Pharmacokinetic consequences of induction of CYP2E1 by ligand stabilization

Pharmacokinetics of chlorzoxazone in rats with diabetes: induction of CYP2E1 on 6-hydroxychlorzoxazone formation

Pharmacokinetics of drug interactions due to ligand stabilization of CYP2E1.

Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1, 3-dimethyluric acid formation

Pharmacological blockage of CYP2E1 and alcohol-mediated liver cancer: is the time ready?

Phenobarbital induces monkey brain CYP2E1 protein but not hepatic CYP2E1, in vitro or in vivo chlorzoxazone metabolism

Phenotype distribution and gender-related differences of CYP2E1 activity in a Chinese population

Phorbol ester induces CYP2E1 in astrocytes, through a protein kinase C‐and tyrosine kinase‐dependent mechanism

Phosphorylation of cytochrome P4502E1 (CYP2E1) by calmodulin dependent protein kinase protein kinase C and cAMP dependent protein kinase

Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1

PI3K inhibitors reverse the suppressive actions of insulin on CYP2E1 expression by activating stress-response pathways in primary rat hepatocytes

Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study

Plasma exosomes exacerbate alcohol-and acetaminophen-induced toxicity via CYP2E1 pathway

Polimorfismos en los genes de la enzima alcohol deshidrogenasa (ADH1) y la citocromo P450 2E1 (CYP2E1) en pacientes con cirrosis y carcinoma …

Polimorfismos nos genes NAT2, CYP2E1, GSTT1, GSTM1 e ABCB11 e hepatotoxicidade induzida pela isoniazida

Polydatin protects rat liver against ethanol-induced injury: involvement of CYP2E1/ROS/Nrf2 and TLR4/NF-B p65 pathway

Polymorphism in CYP1A1 and CYP2E1 genes and susceptibility to leukoplakia in Indian tobacco users

Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers …

Polymorphism of CYP2E1 gene and the risk of lung cancer among African-Americans and Caucasians in Los Angeles County (California).

Polymorphism of metabolizing genes and lung cancer histology: prevalence of CYP2E1 in adenocarcinoma

Polymorphism of the 5′‐Flanking Region of the CYP2E1 Gene: An Association Study With Alcoholism

Polymorphisms in CYP2E1, GSTM1 and GSTT1 and anti-tuberculosis drug-induced hepatotoxicity

Polymorphisms in detoxification genes CYP1A1, CYP2E1, GSTT1 and GSTM1 in gastric cancer susceptibility

Polymorphisms in glutathione S‐transferases GSTM1, GSTT1 and GSTP1 and cytochromes P450 CYP2E1 and CYP1A1 and susceptibility to cirrhosis or …

Polymorphisms in GSTM1, CYP1A1, CYP2E1, and CYP2D6 are Associated with Susceptibility and Chemotherapy Response in Non-small-cell Lung Cancer …

Polymorphisms in GSTT1, GSTZ1, and CYP2E1, Disinfection By-products, and Risk of Bladder Cancer in Spain

Polymorphisms in NEIL-2, APE-1, CYP2E1 and mdm2 genes are independent predictors of gastric cancer Risk in a Northern Jiangsu Population (China)

Polymorphisms in the CYP2E1 and GSTM1 genes as possible protection factors for leprosy patients

Polymorphisms of ADH2, ALDH2 and CYP2E1 in huichol and Mestizo subjects from western México in comparison with other populations of the world

Polymorphisms of Alcohol Metabolizing Enzymes in Indigenous Mexican Population: Unusual High Frequency of CYP2E1*c2 Allele

Polymorphisms of CYP1a1, CYP2E1, GSTM1, GSTT1, and TP53 genes in Amerindians

Polymorphisms of CYP2E1 rs2031920 is not Associated with Risk of Nasopharyngeal Carcinoma in Minangkabau Ethnic Group

Polymorphisms of drug-metabolizing enzyme CYP2E1 in Chinese Uygur population

Polymorphisms of GSTP1 and GSTT1 , but not of CYP2A6 , CYP2E1 or GSTM1 , modify the …

Polymorphisms of NAT2, CYP2E1, GST, and HLA Related to Drug‑Induced Liver Injury in Indonesian Tuberculosis Patients

Polymorphisms of the CYP1A1 and CYP2E1 genes in head and neck squamous cell carcinoma risk

Polymorphisms of the CYP1A1, CYP2E1 and XRCC1 genes and cancer risk in a Southern Italian population: a case–control study

Polymorphisms of the Cytochrome P450 (CYP1A1, CYP2E1) and Microsomal Epoxide Hydrolase (mEPHX) Genes in Cystic Fibrosis and Chronic Respiratory …

Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system

Possible impact of human CYP2E1 polymorphisms on the metabolism of acrylonitrile

Post-transcriptional regulation of rat CYP2E1 expression: role of CYP2E1 mRNA untranslated regions in control of translational efficiency and message stability

Potent mutagenicity of some non-planar tri-and tetrachlorinated biphenyls in mammalian cells, human CYP2E1 being a major activating enzyme

Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1

Povezanost polimorfizama gena TP53 i CYP2E1* 5B s nemikrocelularnim karcinomom pluća

Prediction of The Needs for Benzene Detox with Foods Intake Containing CYP2E1 Enzyme, Sulfation, and Glutathione at Gas Stations Pancoranmas Depok …

Preliminary effects of alcohol and Curcuma longa upon CYP2E1 and hematotoxicity in benzene-induced mice

Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates

Pretreatment with turmeric modulates the inhibitory influence of cisplatin and paclitaxel on CYP2E1 and CYP3A1/2 in isolated rat hepatic microsomes

Progress of research on characteristics of cytochrome P-450 CYP2E1 in protein structure and regulation mechanisms

Promoter function and the role of cytokines in the transcriptional regulation of rabbit CYP2E1 and CYP2E2

Proteasome inhibition potentiates CYP2E1‐mediated toxicity in HepG2 cells

Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice

Protective Effect of Curcumin on Acrylamide-Induced Hepatic and Renal Impairment in Rats: Involvement of CYP2E1

Protective effect of Ornithogalum saundersiae Ait (Liliaceae) against acetaminophen-induced acute liver injury via CYP2E1 and HIF-1α

Protective Effects of CYP2E1 Inhibitors on Metabolic Syndrome-induced Liver Injury in Guinea Pigs

Protective effects of diallyl disulfide against acetaminophen-induced nephrotoxicity: a possible role of CYP2E1 and NF-κB

Protective effects of emodin and chrysophanol isolated from marine fungus Aspergillus sp. on ethanol-induced toxicity in HepG2/CYP2E1 cells

Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in rats

Protective effects of loquat (Eriobotrya japonica) leaves against ethanol-induced toxicity in HepG2 cells transfected with CYP2E1

Protective effects of protein hydrolysate from marine microalgae Navicula incerta on ethanol-induced toxicity in HepG2/CYP2E1 cells

Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells

Proteomics of oxidative stress using inducible CYP2E1 expressing HEPG2 cells and 3T3-L1 adipocytes as model systems

psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1

Pulmonary bioactivation of 1, 1-dichloroethylene is associated with CYP2E1 levels in A/J, CD-1, and C57BL/6 mice

Pulmonary bioactivation of trichloroethylene to chloral hydrate: relative contributions of CYP2E1, CYP2F, and CYP2B1

Pulmonary CYP2E1 bioactivates 1, 1-dichloroethylene in male and female mice.

Pulsatile blood alcohol and CYP2E1 induction during chronic alcohol infusions in rats

Pyrazole induced oxidative liver injury independent of CYP2E1/2A5 induction due to Nrf2 deficiency

Quantification of CYP2E1 in rat liver by UPLC-MS/MS-based targeted proteomics assay: a novel approach for enzyme activity assessment

Quantification of Metabolic Reaction Products Catalysed by CYP2E1 Enzyme Activity: Inhibitory Effect of Cytochrome P450 Enzyme CYP2E1 by Salicylic Acid in Rat …

Quercetin prevents type 1 diabetic liver damage through inhibition of CYP2E1

Quercetin suppressed CYP2E1-dependent ethanol hepatotoxicity via depleting heme pool and releasing CO

Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe …

Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats

Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism

Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and CYP2E1 expression levels

Red meat intake, CYP2E1 and PPARγ polymorphisms, and colorectal cancer risk

Red meat intake, CYP2E1 genetic polymorphisms, and colorectal cancer risk

Reduced systemic toxicity and preserved vestibular toxicity following co-treatment with nitriles and CYP2E1 inhibitors: a mouse model for hair cell loss

Reduction of benzene metabolism and toxicity in mice that lack CYP2E1 expression

Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine

Regulation of CYP2E1 by ethanol and palmitic acid and CYP4A11 by clofibrate in primary cultures of human hepatocytes

Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling

Regulation of X-Ray Irradiation on the Activity and Expression Levels of CYP1A2 and CYP2E1 in Rats

Relation of GSTP1 and CYP2E1 polymorphisms with susceptibility to acute leukemia

Relationship among Qi-deficiency constitution and CYP2E1 gene polymorphisms and anti-tuberculosis drug-induced hepatitis

Relationship between alcoholism and CYP2E1 C/D polymorphism

Relationship between alcoholism and CYP2E1 genotypes

Relationship between CYP2E1 polymorphism and increase of ALT activity during therapy of patients with pulmonary tuberculosis

Relationship between CYP2E1, GSTT1 genetic polymorphisms and susceptibility to gastric cancer

Relationship between cytochrome P450 catalytic cycling and stability: fast degradation of ethanol-inducible cytochrome P450 2E1 (CYP2E1) in hepatoma cells is …

Relationship between gene polymorphism of CYP2E1, CYP1A1, IL-4 and medicamentosa-like dermatitis induced by trichloroethylene

Relationship between genetic polymorphism of CYP2E1 and ALDH2, and possible susceptibility to alcoholism

Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP1B1, CYP2E1, GSTM1, GSTT1, and NAT2) and p53 gene point mutations …

Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP2E1, GSTM1, and NAT2), drinking habits, histological subtypes, and p53 …

Relationship between genetic polymorphisms of metabolizing enzymes CYP2E1, GSTM1 and Kazakh’s esophageal squamous cell cancer in Xinjiang

Relationship between genetic polymorphisms of metabolizing enzymes CYP2E1, GSTM1 and Kazakh’s esophageal squamous cell cancer in Xinjiang, China

Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver

Relationship of ALDH2 rs671 and CYP2E1 rs2031920 with hepatocellular carcinoma susceptibility in East Asians: a meta-analysis

Relationship of anti-tuberculosis drug-induced liver injury and genetic polymorphisms in CYP2E1 and GST

Relationship of CYP2E1 RsaⅠ genetic polymorphism and smoking, alcohol drinking habit with risk of rectal cancer

Relationship of NAT2, CYP2E1 and GSTM1/GSTT1 polymorphisms with mild elevation of liver enzymes in Brazilian individuals under anti-tuberculosis drug …

RELATIONSHIPS BETWEEN GENETIC POLYMORPHISMS IN CYP2D6 AND CYP2E1 GENES AND LIVER MICROSOMAL DRUG OXIDATION ACTIVITIES

Relative contributions of CYP1A2 and CYP2E1 to the bioactivation and clearance of 4-aminobiphenyl in adult mice

Relative roles of CYP2E1 and CYP1A2 in mouse uroporphyria caused by acetone

Relevance of CYP2E1 to non-alcoholic fatty liver disease

Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1

Renal and hepatic accumulation of cadmium and lead in the expression of CYP4F2 and CYP2E1

Requirement Prediction for Toluene Detox with Foods Intake Rich in CYP2E1 Enzyme and Glycine to Prevent Nerve and Kidney Damage at Shoe Home …

Research on Association of Genetic Polymorphism of CYP1A1 and CYP2E1, with Susceptibility to Gastric Cancer

Research on the progress of alcoholic liver disease pathogenesis related to CYP2E1

Research on the relationship between ALDH2 and CYP2E1 gene polymorphism and alcoholic liver disease in Han people

Research on the relationship between polymorphism of CYP2E1 and dermatitis medicamentosa-like of trichloroethylene [J]

Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression

Response: Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?

Resveratrol downregulates CYP2E1 and attenuates chemically induced hepatocarcinogenesis in SD rats

Resveratrol pretreatment affects CYP2E1 activity of chlorzoxazone in healthy human volunteers

Rifampicin suppresses hepatic CYP2E1 expression and minimizes DNA injury caused by carbon tetrachloride in perivenular hepatocytes of mice

Risk assessment: toxicity from chemical exposure resulting from enhanced expression of CYP2E1

Role and importance of polymorphisms with respect to DNA methylation for the expression of CYP2E1 enzyme

Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability

Role of alcohol and genetic polymorphisms of CYP2E1 and ALDH2 in breast cancer development

Role of brain acetaldehyde in drinking preference: genetic modification of alcohol oxidizing enzymes catalase and CYP2E1 in C57BL/6 mice and their …

Role of calcium and calcium-activated proteases in CYP2E1-dependent toxicity in HEPG2 cells

Role of CYP1A2 and CYP2E1 in the pentoxifylline ciprofloxacin drug interaction

Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias

Role of CYP2E1 (PstI/RsaI) gene polymorphisms on the tacrolimus drug toxicity of kidney transplantations among South Indians

Role of CYP2E1 activity in endoplasmic reticulum ubiquitination, proteasome association, and the unfolded protein response

Role of CYP2E1 and NQO1 polymorphisms in oxidative stress derived cancer in Thais with and without dyslipidemia

Role of CYP2E1 and saturation kinetics in the bioactivation of thioacetamide: Effects of diet restriction and phenobarbital

Role of CYP2E1 gene polymorphisms association with hepatitis risk in Northeast India

Role of CYP2E1 Immunoglobulin G4

Role of CYP2E1 immunoglobulin G4 subclass antibodies and complement in pathogenesis of idiosyncratic drug-induced hepatitis

Role of CYP2E1 in deramciclane metabolism

Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo

Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity

Role of CYP2E1 in Impaired Nitric Oxide Synthase (NOS)‐Dependent Cerebral Vasodilation During Chronic Alcohol Consumption

Role of CYP2E1 in ketone-stimulated insulin release in pancreatic B-cells

Role of CYP2E1 in Mitochondrial Dysfunction and Hepatic Injury by Alcohol and Non-Alcoholic Substances

Role of CYP2E1 in mitochondrial dysfunction and hepatic tissue injury in alcoholic and non-alcoholic diseases

Role of CYP2E1 in the Epoxidation of Acrylamide to Glycidamide and Formation of DNA and Hemoglobin Adducts

Role of CYP2E1 in the hepatotoxicity of acetaminophen

Role of CYP2E1 in the mouse model of MPTP toxicity

Role of CYP2E1 in the pathogenesis of alcoholic liver disease

Role of CYP2E1 in the pathogenesis of alcoholic liver disease: modifications by cAMP and ubiquitin-proteasome pathway

Role of CYP2E1 in thioacetamide-induced mouse hepatotoxicity

Role of CYP2E1 polymorphisms in breast cancer: a systematic review and meta-analysis

Role of CYP2E1-mediated metabolism in the acute and vestibular toxicities of nineteen nitriles in the mouse

Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and CYP2E1 (–/–) mice

Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1

Role of exposure/recovery schedule in micronuclei induction by several promutagens in V79-derived cells expressing human CYP2E1 and SULT1A1

Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1

Role of mouse CYP2E1 in the O-hydroxylation of p-nitrophenol: comparison of activities in hepatic microsomes from CYP2E1 (-/-) and wild-type mice

Role of nitric oxide and nuclear factor-κB in the CYP2E1 potentiation of tumor necrosis factor α hepatotoxicity in mice

Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia

Role of P38 MAP kinase in CYP2E1 dependent arachidonic acid toxicity

Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity

Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity

Role of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells

Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and …

Role of the Genetic Polymorphisms in the 5′‐Flanking Region for Transcriptional Regulation of the Human CYP2E1 Gene

Role of the Liver-Enriched Transcription Factor HNF-1α in Expression of the CYP2E1 Gene

Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells

Roles of CYP1A1 and CYP2E1 Gene Polymorphisms in Oral Submucous Fibrosis

Roles of CYP2E1 in 1, 2‐dichloroethane‐induced liver damage in mice

Roles of CYP2E1 in liver damage induced by 1, 2-dichloroethane

Romidepsin (FK228) in a Mouse Model of Lipopolysaccharide-Induced Acute Kidney Injury is Associated with Down-Regulation of the CYP2E1 Gene

RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure

RsaI but not DraI polymorphism in CYP2E1 gene increases the risk of gastrointestinal cancer in Malaysians: a case–control study

Ruthenium red protects HepG2 cells overexpressing CYP2E1 against acetaminophen cytotoxicity

S29. 1 CORRELATION BETWEEN SPERMATOGENESIS DISORDERS AND CYP2E1 MRNA EXPRESSION IN RATS TESTES FOLLOWING CHRONIC …

S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury

S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice

Safrole-DNA adducts in human peripheral blood—an association with areca quid chewing and CYP2E1 polymorphisms

Salidroside protects mice against CCl4-induced acute liver injury via down-regulating CYP2E1 expression and inhibiting NLRP3 inflammasome activation

Salvia fruticosa Modulates mRNA Expressions and Activity Levels of Xenobiotic Metabolizing CYP1A2, CYP2E1, NQO1, GPx, and GST Enzymes in Human …

Scrophularia ningpoensis, Asparagus cochinchinensis and Ophiopogon japonicas on contents of CYP450 and activities of CYP3A, CYP2E1 and CYP1A2 in rat

Selective time-and NADPH-dependent inhibition of human CYP2E1 by clomethiazole

Serum autoantibodies against cytochrome P450 2E1 (CYP2E1) predict severity of liver graft hepatitis C recurrence

Serum autoantibodies against cytochrome P450 2E1 (CYP2E1) predict severity of necroinflammation of recurrent hepatitis C

Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1

Sex steroid hormones regulate constitutive expression of CYP2E1 in female mouse liver

Shanxi aged vinegar prevents alcoholic liver injury by inhibiting CYP2E1 and NADPH oxidase activities

Short-term treatment with alcohols causes hepatic steatosis and enhances acetaminophen hepatotoxicity in CYP2E1 (-/-) mice

Significance of genetic polymorphisms at multiple loci of CYP2E1 in the risk of development of childhood acute lymphoblastic leukemia

Significant genotype difference in the CYP2E1 PstI polymorphism of indigenous groups in Sabah, Malaysia with Asian and non-Asian populations

Silver Nanoparticle-Doped Poly (8-Anilino-1-Naphthalene Sulphonic Acid)/CYP2E1 Nanobiosensor for Isoniazid-A First Line Anti-Tuberculosis Drug

Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?

Similarity Check: Genotype Polymorphisms Of Nat2 And CYP2E1 Genes Associated With Drug Induced Liver Injury (Dili) In Indonesian Tuberculosis Patients

Simultaneous phenotyping of CYP2E1 and CYP3A using oral chlorzoxazone and midazolam microdoses

Single-nucleotide polymorphisms in cytochrome P450 2E1 (CYP2E1) 3′-untranslated region affect the regulation of CYP2E1 by miR-570

Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes

Spectrophotometric Analysis of Human CYP2E1-Catalyzed p-Nitrophenol Hydroxylation

Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity

St. John’s wort extract induces CYP3A and CYP2E1 in the Swiss Webster mouse

Stable expression of human CYP2E1 in Chinese hamster cells: high sensitivity to N, N-dimethylnitrosamine in cytotoxicity testing

Striking LD50 variation associated with fluctuations of CYP2E1-positive cells in hepatic lobule during chronic CCl4 exposure in mice

Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes

Structure-functional characterization of cytochrome P4502E1 (CYP2E1)

Structure-toxicity relationship study of para-halogenated styrene analogues in CYP2E1 transgenic cells

Studies on Pharmacokinetic Interaction Among CYP1A2, CYP2E1 and CYP3A4 Probes in Rats [J]

Study of CYP2E1 gene RsaI/PstI polymorphisms in patients with gastric cancer in north of Iran

Study of genetic polymorphisms of CYP2E1 and GSTM1

Study of polymorphisms in the CYP2E1 gene in patients with alcoholic pancreatitis

Study of the fragmentation mechanism of protonated 6-hydroxychlorzoxazone: application in simultaneous analysis of CYP2E1 activity with major human cytochrome …

STUDY ON AA METABOLISM IN RAT LIVER AND THE EXPRESSION OF CYP2E1

Study on Chinese medicine constitution and its relation with CYP2E1 gene polymorphisms of anti‐tuberculosis drug‐induced hepatitis

Study on inhibitory effect of water extract of Polygonum multiflorum on CYP1A2 and CYP2E1 enzymatic activities and mRNA expressions in rat liver

Study on the association between CYP2E1 enzymes and susceptibility of alcoholic liver disease

Study on the association between genetic polymorphism of CYP2E1, GSTM1 and susceptibility of lung cancer

Study the effect of Baijie Capsule on cytochrome P450 isozymes CYP2C19, CYP2E1 by cocktail probe drugs

Study the effect of cytochrome p450 isozymes cyp1A2, cyp3A4, CYP2E1 following administration of Zhenqi Fuzheng Capsules by cocktail probe drugs [J]

Subcellular localization of rat CYP2E1 impacts metabolic efficiency toward common substrates

Sulforaphane induces Nrf2 and protects against CYP2E1-dependent binge alcohol-induced liver steatosis

Suppression of cytochrome P450 2E1 promoter activity by interferon-γ and loss of response due to the-71G> T nucleotide polymorphism of the CYP2E1* 7B allele

Sus scrofa mRNA for cytochrome p450 2E1 (CYP2E1 gene)

Sus scrofa partial CYP2E1 gene for cytochrome p450 2E1, exon 9 and partial CDS

Susceptibility to the acute toxicity of acrylonitrile in streptozotocin-induced diabetic rats: protective effect of phenethyl isothiocyanate, a phytochemical CYP2E1 …

Synergistic association of PTGS2 and CYP2E1 genetic polymorphisms with lung cancer risk in northeastern Chinese

Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury

Synergistic toxicity of iron and arachidonic acid in HepG2 cells overexpressing CYP2E1

Synonymous mutation rs2515641 affects CYP2E1 mRNA and protein expression and susceptibility to drug-induced liver injury

Tandem Repeat Polymorphism of the CYP2E1 Gene: An Association Study With Esophageal Cancer and Lung Cancer

Targeted CYP2E1 quantification and its correlation to currently acceptable clinical biochemical indices

Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation

Tetra primer ARMS PCR optimization to detect single nucleotide polymorphisms of the CYP2E1 gene

The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65

The activity, protein, and mRNA expression of CYP2E1 and CYP3A1 in rats after exposure to acute and chronic high altitude hypoxia

The ADH3* 2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men

The alcohol-inducible form of cytochrome P450 (CYP2E1): role in toxicology and regulation of expression

The association between CYP2E1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs: a meta-analysis

The Association of CYP2E1 Polymorphism and Environmental Factor in Nasopharyngeal Carcinoma Patients

The Changes in the Analgesic Effect of Probe Drug Chlorzoxazone Metabolized by CYP2E1 on Alcoholic Liver Injury in Rats

The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2-and Akt-dependent mechanism

The CYP2E1-humanized transgenic mouse: role of CYP2E1 in acetaminophen hepatotoxicity

The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine

The difference of metabolism activity of CYP2E1 between in immune liver damage rats and in alcohol-mediated hepatic injury rats

The effect of changes in CYP2E1 activity in the liver on toxicity and carcinogenicity of diethylnitrosamine in mice

The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells

The effect of endotoxin on hepatocyte nuclear factor 1 nuclear protein binding: potential implications on CYP2E1 expression in the rat

The effect of ethanol and nitric oxide on the N-nitrosodimethylamine formation in HepG2 cells overexpressing CYP2E1

THE EFFECT OF ETHANOL ON COUMARIN METABOLISM AND CYTOTOXICITY IN TRANSFECTED CULTURES OF HEPG2 CELLS WITH CYP2E1 EXPRESSION.

The effect of ethanol-induced CYP2E1 on proteasome activity: the role of 4-hydroxynonenal

The Effect of Huangqi on CYP2E1 Activity of Diabetic Rats

The effect of isoniazid containing regimen on CYP2E1 during antituberculosis therapy.

The effect of isoniazid on CYP2E1-and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney

The effect of lycopene on the total cytochrome P450, CYP1A2 and CYP2E1

The effect of organic solvents and CYP1A1, CYP2E1, GSTM1 polymorphisms on the development of acute lymphoblastic leukemia in Quebec children

The effect of quercetin on the pharmacokinetics of chlorzoxazone, a CYP2E1 substrate, in healthy subjects

The effect of SNPs in the promoter on expression of CYP2E1 gene and boar taint

The effects of alcohol and diallyl sulphide on CYP2E1 activity in humans: a phenotyping study using chlorzoxazone

The effects of bovine serum albumin on kinetic characterization of human liver microsomal CYP2C19 and CYP2E1 activities

The Effects of CYP2E1 on Hepatic Gene Expression in 129/Sv-CYP2E1^ tm1Gonz/J and 129S1/SvImJ Mice Exposed to Hydrazine

The effects of non-esterified fatty acids and β-hydroxybutyrate on the hepatic CYP2E1 in cows with clinical ketosis

The Effects of Poly IC and Human Interferon ɑ on Rat Hepatic Cyp4a1 and CYP2E1.

The effects of the ALDH2* 1/2, CYP2E1 c1/c2 and C/D genotypes on blood ethanol elimination and the human serotonin receptor (HTR2) gene Msp1 polymorphism in …

THE EFFECTS OF THE ALDH2*1/2, CYP2E1 C1/C2 AND C/D GENOTYPES ON BLOOD ETHANOL ELIMINATION

The effects of toluene on the total CYP450 content and on levels of CYP2E1 and 2B6 Isoforms in the rat liver

The essential role of CYP2E1 in metabolism and hepatotoxicity of N,N-dimethylformamide using a novel CYP2E1 knockout mouse model and a population study

The ethanol elimination pharmacokinetics–the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism

The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage

The genetic profiles of CYP1A1, CYP1A2 and CYP2E1 enzymes as susceptibility factor in xenobiotic toxicity in Turkish population

The genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fish Poeciliopsis

The genotype of CYP2E1 and liver-derived serum enzymes

The GST T1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function

The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphisms in a Finish study population

The impact of CYP1A2 and CYP2E1 genes polymorphism on theophylline response

The impact of CYP2E1 genetic variability on risk assessment of VOC mixtures

The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model

The impact of psychogenic stressors on oxidative stress markers and patterns of CYP2E1 expression in mice liver

The importance of CYP2E1 in the pathogenesis of alcoholic liver disease and drug toxicity and the role of the proteasome

The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation

The induction of the human hepatic CYP2E1 gene by interleukin 4 is transcriptional and regulated by protein kinase C

The influence of genetic polymorphism of CYP2E1 on the development of alcohol liver cirrhosis

The influence of Jiuganning decoction on the content of CYP2E1 and cytokine IL-6, TNF in rats models of alcoholic hepatic injury

The Inhibitory Effect of the Derris scandens Extract on Cytochrome P450 2E1 (CYP2E1)-associated Aniline-4-Hydroxylase in vitro

The LRP6 functional mutation rs2302685 contributes to individual susceptibility to alcoholic liver injury related to the Wnt/β-catenin-TCF1-CYP2E1 signaling pathway

The Meta Isomer of Acetaminophen Is A Time Dependent Inhibitor of Human CYP2E1

The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin

The modeling of interactions of the CYP2E1 isoform of human cytochrome P450 with substrates

The modifying effect of CYP2E1, GST, and mEH genotypes on the formation of hemoglobin adducts of acrylamide and glycidamide in workers exposed to acrylamide

The molecular mechanism regulating 24‐hour rhythm of CYP2E1 expression in the mouse liver

The NH2-terminal region of rabbit CYP2E1 is not essential for interaction with NADPH-cytochrome P450 reductase

The Physiological Mechanism of Improved Formaldehyde Resistance in Petunia hybrida Harboring a Mammalian CYP2E1 Gene

The Physiological Mechanism of Petunia hybrida Harboring Mammalian CYP2E1 Gene Improving Resistance to Formaldehyde

The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone

The polymorphism of CYP2E1 Rsa I/Pst I gene and susceptibility to respiratory system cancer: a systematic review and meta-analysis of 34 studies

The polymorphism rs2480258 within CYP2E1 is associated with different rates of acrylamide metabolism in vivo in humans

The possible mechanisms of CYP2E1 interactions with HSP90 and the influence of ethanol on them

The regulation of CYP2E1 gene expression and its role in breast cancer

The research on the relationship between CD44, CYP2E1 genetic polymorphisms and esophageal cancer

The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes

The role of CYP2A6 and CYP2E1 in the metabolism of 3-methylindole in porcine hepatocytes.

The role of CYP2E1 and 2B1 in metabolic activation of benzene derivatives

The role of CYP2E1 and CYP4A in the development of non-alcoholic steatohepatitis

The Role of CYP2E1 IgG4 Subclass Autoantibodies in the Development of Anesthetic Sensitization

The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system

The Role of CYP2E1 in the Drug Metabolism or Bioactivation in the Brain

The role of CYP2E1 in the protection of garlic oil’s from n-hexane-induced neurotoxicity

THE ROLE OF CYP2E1 POLYMORPHISM IN THE ACTIVATION OF PROCARCINOGEN METABOLISM OF NASOPHARYNGEAL CARCINOMA

The role of inflammatory and oxidative stress, CYP2E1 and bile acid disturbance in rat liver injury induced by isoniazid and lipopolysaccharide co-treatment

The role of phosphatidylinositol 3-kinase, Src kinase, and protein kinase A signaling pathways in insulin and glucagon regulation of CYP2E1 expression

The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: effect on age of presentation and dependence on alcohol …

The WNT/β-catenin pathway is a transcriptional regulator of CYP2E1, CYP1A2, and aryl hydrocarbon receptor gene expression in primary human hepatocytes

Theoretical study of the mechanism of acetaldehyde hydroxylation by compound I of CYP2E1

Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model

Therapeutic potential of CYP2E1 inhibitor combined N-acetyl-cysteine in acute acrylonitrile intoxication in rats

Tightly regulated and inducible expression of rabbit CYP2E1 using a tetracycline-controlled expression system

Tissue-specific expression and methylation of the human CYP2E1 gene

Toward a systems approach to cytochrome P450 ensemble: interactions of CYP2E1 with other P450 species and their impact on CYP1A2

Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes

Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity

Transcriptional activity of the tandem repeat polymorphism in the 5′‐flanking region of the human CYP2E1 gene

Transcriptional control of CYP2E1 in the perivenous liver region and during starvation

Transcriptional control of the rat hepatic CYP2E1 gene.

Transfected HepG2 cells for evaluation of catechin effects on alcohol-induced CYP2E1 cytotoxicity

Transgenic alfalfa plants co-expressing glutathione S-transferase (GST) and human CYP2E1 show enhanced resistance to mixed contaminates of heavy metals and …

Transgenic plant regeneration of tobacco (Nicotiana tabacum) haboring mammalian CYP2E1 gene

Transgenic plants of Petunia hybrida harboring the CYP2E1 gene efficiently remove benzene and toluene pollutants and improve resistance to formaldehyde

Translational activation of ethanol-inducible cytochrome P450 (CYP2E1) by isoniazid

Trifluoroacetylated adducts in spermatozoa, testes, liver and plasma and CYP2E1 induction in rats after subchronic inhalatory exposure to halothane

Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1

Trimethadione N-demethylation by rat liver CYP2E1 in vitro.

TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity

TRPV4 attenuates M1 polarization and subsequent NASH progression by stalling CYP2E1-mediated redox toxicity via eNOS.

TRPV4 Modulates CYP2E1 Function in Nonalcoholic Steatohepatitis Progression

Ultrasensitive quantification of the CYP2E1 probe chlorzoxazone and its main metabolite 6-hydroxychlorzoxazone in human plasma using ultra performance liquid …

Undernutrition during hyperoxic exposure induces CYP2E1 in rat liver

Unraveling CYP2E1 haplotypes in alcoholics from Central Brazil: A comparative study with 1000 genomes population

UPREGULATING OF CYP2E1 IN ETHANOL-FED MICE WITH TRANSGENIC OVEREXPRESSION OF CTRP3

Upregulation of CYP2E1 and cyp3a activities in histamine-deficient histidine decarboxylase gene targeted mice

Upregulation of CYP2E1 expression causes oxidative damage induced by 2-chloroethanol in primary cultured rat astrocytes

Urinary Biomarker of Prenatal Exposure to Disinfection Byproducts, Maternal Genetic Polymorphisms in CYP2E1 and GSTZ1, and Birth Outcomes

Urinary excretion of 6‐hydroxychlorzoxazone as an index of CYP2E1 activity

Use of CYP2E1‐transfected human liver cell lines in elucidating the actions of ethanol

Use of Cytochrome P450 2E1 (CYP2E1) Knockout Transgenic Mouse Model to Study the Role of CYP2E1 in Carbon Tetrachloride-and Alcohol-mediated …

Use of molecular simulation for mapping conformational CYP2E1 epitopes

Use of the CYP2E1 genotype and phenotype for the biological monitoring of occupational exposure to styrene

Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques

Validation of the (ω-l)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1

Value of polymorphisms and DNA methylation for the expression of CYP2E1 enzyme: implications in pharmacogenomics

Variable Number of Tandem Repeats (VNTR) gene polymorphism of CYP2E1 in patients with pancreatic adenocarcinoma

Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome?

Variations in expression of CYP2E1 and COUP-TF1 proteins between Large White and Duroc cross-breeds

Voglibose potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen by inducing CYP2E1 in rats

Watercress has no importance for the elimination of ethanol by CYP2E1 inhibition

XRCC1 and CYP2E1 polymorphisms as susceptibility factors of plasma mutant p53 protein and anti-p53 antibody expression in vinyl chloride monomer-exposed …

XRCC1, CYP2E1 and ALDH2 genetic polymorphisms and sister chromatid exchange frequency alterations amongst vinyl chloride monomer-exposed polyvinyl …

Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like

ZSCAN25 and CYP2E1 polymorphisms is risk factors for ischemic stroke in a Chinese Han population: a case control study

π–π Stacking mediated drug–drug interactions in human CYP2E1

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

Danshen (Salvia miltiorrhiza) water extract inhibits paracetamol-induced toxicity in primary rat hepatocytes via reducing CYP2E1 activity and oxidative stress

Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance

… patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, CYP2E1, gstm1 and gstt1

In vitro inhibition of human CYP2E1 and CYP3A by quercetin and myricetin in hepatic microsomes is not gender dependent

Cytochrome P450 2E1 (CYP2E1) positively regulates lipid catabolism and induces browning in 3T3-L1 white adipocytes

Selective time-and NADPH-dependent inhibition of human CYP2E1 by clomethiazole

Expression and activities of hepatic cytochrome P450 (CYP1A, CYP2A and CYP2E1) in entire and castrated male pigs

Quercetin suppressed CYP2E1-dependent ethanol hepatotoxicity via depleting heme pool and releasing CO

CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis

Effects of unprocessed versus vinegar-processed Schisandra chinensis on the activity and mRNA expression of CYP1A2, CYP2E1 and CYP3A4 enzymes in rats

… in rats induced by aqueous extract of Polygoni Multiflori Radix, root of Polygonum multiflorum related to the activity inhibition of CYP1A2 or CYP2E1

Association between the CYP2E1 polymorphisms and lung cancer risk: a meta-analysis

Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes

Polymorphisms in GSTM1, CYP1A1, CYP2E1, and CYP2D6 are associated with susceptibility and chemotherapy response in non-small-cell lung cancer patients

Role of CYP2E1 polymorphisms in breast cancer: a systematic review and meta-analysis

TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity

Tetra primer ARMS PCR optimization to detect single nucleotide polymorphisms of the CYP2E1 gene

The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation

Genetic variants of ALDH2-rs671 and CYP2E1-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population

Genetic polymorphisms of CYP2E1 and DNA repair genes HOGG1 and XRCC1: association with hepatitis B related advanced liver disease and cancer

Cytochrome P450 CYP2E1 suppression ameliorates cerebral ischemia reperfusion injury

Association of genetic polymorphisms of CYP2E1, NAT2, GST and SLCO1B1 with the risk of anti-tuberculosis drug-induced liver injury: a systematic review …

Genetic polymorphisms of CYP2E1 and GSTM1 loci and susceptibility to anti-tuberculosis drug-induced hepatotoxicity

Nicotinamide N-oxidation by CYP2E1 in human liver microsomes

CYP1A1 and CYP2E1 genotypes and risk of esophageal squamous cell carcinoma in a high-incidence region, Kashmir

Potent mutagenicity of some non-planar tri-and tetrachlorinated biphenyls in mammalian cells, human CYP2E1 being a major activating enzyme

Chronic acrylamide exposure in male mice results in elevated DNA damage in the germline and heritable induction of CYP2E1 in the testes

Shanxi aged vinegar prevents alcoholic liver injury by inhibiting CYP2E1 and NADPH oxidase activities

Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 over-expressing VL-17A cells

The possible mechanisms of CYP2E1 interactions with HSP90 and the influence of ethanol on them

Genetic polymorphisms of CYP2E1, GST, and NAT2 enzymes are not associated with risk of breast cancer in a sample of Lebanese women

Urinary biomarker of prenatal exposure to disinfection byproducts, maternal genetic polymorphisms in CYP2E1 and GSTZ1, and birth outcomes

CYP2E1 phenotype in Mexican workers occupationally exposed to low levels of toluene

Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4

Genetic polymorphism of cytochrome P450 (CYP) 1A1, CYP1A2, and CYP2E1 genes modulate susceptibility to gastric cancer in patients with Helicobacter …

Cooperative effects for CYP2E1 differ between styrene and its metabolites

Polymorphisms of the CYP1A1 and CYP2E1 genes in head and neck squamous cell carcinoma risk

Effectiveness of antioxidant treatments on cytochrome P450 2E1 (CYP2E1) activity after alcohol exposure in humans and in vitro models: A systematic review

Alteration in the expression of cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the liver of mouse induced by microcystin-LR

Exploration of inhibition potential of isoniazid and its metabolites towards CYP2E1 in human liver microsomes through LC-MS/MS analysis

Application of an updated physiologically based pharmacokinetic model for chloroform to evaluate CYP2E1-mediated renal toxicity in rats and mice

Genetic polymorphisms of drug‐metabolizing phase I enzymes CYP2E1, CYP2A6 and CYP3A5 in South Indian population

HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma cells

Associations between CYP1A1 and CYP2E1 polymorphisms and susceptibility to esophageal cancer in Chaoshan and Taihang areas of China

Featured structure-activity relationships for some tri-and tetrachlorobiphenyls in human CYP2E1-activated mutagenicity—impact of the extent of ortho-chlorination

Polymorphisms of NAT2, CYP2E1, GST, and HLA related to drug-induced liver injury in indonesian tuberculosis patients

CHIP−/−-mouse liver: adiponectin-AMPK-FOXO-activation overrides CYP2E1-elicited JNK1-activation, delaying onset of NASH: therapeutic implications

Protective effect of curcumin on acrylamide-induced hepatic and renal impairment in rats: Involvement of CYP2E1

Associations of CYP2E1 rs2031920 and rs3813867 polymorphisms with colorectal cancer risk: a systemic review and meta-analysis

Altered vulnerability to asthma at various levels of ambient Benzo [a] Pyrene by CTLA4, STAT4 and CYP2E1 polymorphisms

CYP2E1 Rsa I/Pst I polymorphism contributes to oral cancer susceptibility: a meta-analysis

Genetic polymorphisms of SLCO1B1, CYP2E1 and UGT1A1 and susceptibility to anti-tuberculosis drug-induced hepatotoxicity: a Chinese population-based …

CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population

Triptolide regulates oxidative stress and inflammation leading to hepatotoxicity via inducing CYP2E1

Resveratrol downregulates CYP2E1 and attenuates chemically induced hepatocarcinogenesis in SD rats

Development of an IgY antibody-based immunoassay for the screening of the CYP2E1 inhibitor/enhancer from herbal medicines

Inhibition of CYP2E1 leads to decreased malondialdehyde–acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure

Association between polymorphism of GSTP1, GSTT1, GSTM1 and CYP2E1 genes and susceptibility to benzene-induced hematotoxicity

… bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in …

Human placental lactogen induces CYP2E1 expression via PI 3-kinase pathway in female human hepatocytes

Regulation of X-Ray Irradiation on the Activity and Expression Levels of CYP1A2 and CYP2E1 in Rats

Nanoformulated SOD1 ameliorates the combined NASH and alcohol-associated liver disease partly via regulating CYP2E1 expression in adipose tissue and liver

The essential role of CYP2E1 in metabolism and hepatotoxicity of N, N-dimethylformamide using a novel CYP2E1 knockout mouse model and a population study

Genotoxicity of 1‐methylpyrene and 1‐hydroxymethylpyrene in chinese hamster V79‐derived cells expressing both human CYP2E1 and SULT1A1

Simultaneous phenotyping of CYP2E1 and CYP3A using oral chlorzoxazone and midazolam microdoses

Genetic Polymorphisms in CYP2E1: Association with Schizophrenia Susceptibility and Risperidone Response in the Chinese Han Population

Human CYP2E1-activated mutagenicity of dioxin-like PCBs 105 and 118—Experimental data consistent with molecular docking results

CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes

Aidi injection altered the activity of CYP2D4, CYP1A2, CYP2C19, CYP3A2, CYP2E1 and CYP2C11 in normal and diethylnitrosamine-induced hepatocellular …

Investigation of the inhibition of eight major human cytochrome P450 isozymes by a probe substrate cocktail in vitro with emphasis on CYP2E1

Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury

Inhibitory effects of cytochrome P450 enzymes CYP1A2, CYP2A6, CYP2E1 and CYP3A4 by extracts and alkaloids of Gelsemium elegans roots

Concentration-dependent inhibitory effect of baicalin on the plasma protein binding and metabolism of chlorzoxazone, a CYP2E1 probe substrate, in rats in …

The activity, protein, and mRNA expression of CYP2E1 and CYP3A1 in rats after exposure to acute and chronic high altitude hypoxia

Synergistic association of PTGS2 and CYP2E1 genetic polymorphisms with lung cancer risk in northeastern Chinese

Structural basis for cooperative binding of azoles to CYP2E1 as interpreted through guided molecular dynamics simulations

CYP2E1 plays a suppressive role in hepatocellular carcinoma by regulating Wnt/Dvl2/β-catenin signaling

Genetic interaction between NAT2, GSTM1, GSTT1, CYP2E1, and environmental factors is associated with adverse reactions to anti-tuberculosis drugs

Polymorphisms of drug-metabolizing enzyme CYP2E1 in Chinese Uygur population

Organosulfur compounds in fermented garlic extracts and the effects on alcohol induced cytotoxicity in CYP2E1-transfected HepG2 cells

TA allele of rs2070673 in the CYP2E1 gene is associated with lobular inflammation and nonalcoholic steatohepatitis in patients with biopsy‐proven nonalcoholic fatty …

Metallothionein protects against isoniazid-induced liver injury through the inhibition of CYP2E1-dependent oxidative and nitrosative impairment in mice

The impact of psychogenic stressors on oxidative stress markers and patterns of CYP2E1 expression in mice liver

A single nucleotide polymorphism in the CYP2E1 gene promoter affects skatole content in backfat of boars of two commercial Duroc-sired crossbred populations

Salvia fruticosa Modulates mRNA Expressions and Activity Levels of Xenobiotic Metabolizing CYP1A2, CYP2E1, NQO1, GPx, and GST Enzymes in Human …

Ethanol self-administration and nicotine treatment induce brain levels of CYP2B6 and CYP2E1 in African green monkeys

Inhibition of CYP2E1 attenuates myocardial dysfunction in a murine model of insulin resistance through NLRP3-mediated regulation of mitophagy

CYP2E1 RsaI/PstI polymorphism and gastric cancer susceptibility: meta-analyses based on 24 case-control studies

CYP2E1-catalyzed alcohol metabolism: Role of oxidant generation in interferon signaling, antigen presentation and autophagy

Role of exposure/recovery schedule in micronuclei induction by several promutagens in V79-derived cells expressing human CYP2E1 and SULT1A1

Protective effect of Schisandra chinensis total lignans on acute alcoholic-induced liver injury related to inhibiting CYP2E1 activation and activating the Nrf2/ARE …

Effect of Acrylamide Treatment on CYP2E1 Expression and Redox Status in Rat Hepatocytes

Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma

… Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe …

Association of CYP2E1, STK15 and XRCC1 polymorphisms with risk of breast cancer in Malaysian women

Alcohol suppresses cardiovascular diurnal variations in male normotensive rats: Role of reduced PER2 expression and CYP2E1 hyperactivity in the heart

Reduced systemic toxicity and preserved vestibular toxicity following co-treatment with nitriles and CYP2E1 inhibitors: a mouse model for hair cell loss

CYP2E1 impairs GLUT4 gene expression and function: NRF2 as a possible mediator

Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures

Relationship of NAT2, CYP2E1 and GSTM1/GSTT1 polymorphisms with mild elevation of liver enzymes in Brazilian individuals under anti-tuberculosis drug …

CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms

The impact of CYP1A2 and CYP2E1 genes polymorphism on theophylline response

Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1

The modifying effect of CYP2E1, GST, and mEH genotypes on the formation of hemoglobin adducts of acrylamide and glycidamide in workers exposed to acrylamide

Adverse outcome pathway on CYP2E1 activation leading to liver cancer

Increased DNA damage is not associated to polymorphisms in OGGI DNA repair gene, CYP2E1 detoxification gene, and biochemical and hematological findings in …

CYP2E1 and miRNA‐378a‐3p contribute to acetaminophen‐or tripterygium glycosides‐induced hepatotoxicity

Dietary aflatoxin B1 intake, genetic polymorphisms of CYP1A2, CYP2E1, EPHX1, GSTM1, and GSTT1, and gastric cancer risk in Korean

Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes

Allyl methyl trisulfide protected against acetaminophen (paracetamol)-induced hepatotoxicity by suppressing CYP2E1 and activating Nrf2 in mouse liver

Glabridin attenuates paracetamol-induced liver injury in mice via CYP2E1-mediated inhibition of oxidative stress

A regulatory variant in CYP2E1 affects the risk of lung squamous cell carcinoma

Insulin resistance enhances binge ethanol-induced liver injury through promoting oxidative stress and up-regulation CYP2E1

Association between CYP2E1 polymorphisms and risk of gastric cancer: An updated meta‑analysis of 32 case‑control studies

CYP2E1 gene polymorphisms related to the formation of coronary artery lesions in Kawasaki disease

Insights into insulin-mediated regulation of CYP2E1: miR-132/-212 targeting of CYP2E1 and role of phosphatidylinositol 3-kinase, Akt (protein kinase B), mammalian …

CYP1AI and CYP2E1 gene polymorphisms may increase susceptibility to Oral Submucous Fibrosis among betel quid chewers of Eastern India

Extract of Jasminum grandiflorum L. alleviates CCl4-induced liver injury by decreasing inflammation, oxidative stress and hepatic CYP2E1 expression in mice

Effect of CYP2E1 gene polymorphisms on lamb odor and flavor in Indonesian sheep

Coordinate regulation of CYP2E1 by β-catenin-and hepatocyte nuclear factor 1α-dependent signaling

Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription

Association between polymorphisms in the CYP1A1, CYP2E1 and GSTM1 genes, and smoking, alcohol and upper digestive tract carcinomas in a high …

Intracellular ethanol‐mediated oxidation and apoptosis in HepG2/CYP2E1 cells impaired by two active peptides from seahorse (Hippocampus kuda bleeler) protein …

The genetic profiles of CYP1A1, CYP1A2 and CYP2E1 enzymes as susceptibility factor in xenobiotic toxicity in Turkish population

CYP2E1 PstI/RsaI polymorphism and interaction with alcohol consumption in hepatocellular carcinoma susceptibility: evidence from 1,661 cases and 2,317 controls

A novel role of CYP2E1 in human megakaryocyte development

Inhibition of CYP2E1 and activation of Nrf2 signaling pathways by a fraction from Entada africana alleviate carbon tetrachloride-induced hepatotoxicity

Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia

The LRP6 functional mutation rs2302685 contributes to individual susceptibility to alcoholic liver injury related to the Wnt/β-catenin-TCF1-CYP2E1 signaling pathway

Hepatoprotective Effect of Loquat Leaf Flavonoids in PM2.5-Induced Non-Alcoholic Fatty Liver Disease via Regulation of IRs-1/Akt and CYP2E1/JNK Pathways

… ‐en‐Y gastric bypass surgery influenced pharmacokinetics of several drugs given as a cocktail with the highest impact observed for CYP1A2, CYP2C8 and CYP2E1 …

Alcohol intake and folate antagonism via CYP2E1 and ALDH1: Effects on oral carcinogenesis

High CYP2E1 activity aggravates hepatofibrosis by limiting macrophage polarization towards the M2 phenotype

… of interactions of cathinone with human recombinant cytochrome P450 CYP (1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5

Upregulation of CYP2E1 expression causes oxidative damage induced by 2-chloroethanol in primary cultured rat astrocytes

Relationships among N, N-dimethylformamide exposure, CYP2E1 and TM6SF2 genes, and non-alcoholic fatty liver disease

Epididymal CYP2E1 plays a critical role in acrylamide-induced DNA damage in spermatozoa and paternally mediated embryonic resorptions

CYP2E1, oxidative stress and MAPK signaling pathways in alcohol-induced hepatotoxicity

Romidepsin (FK228) in a mouse model of lipopolysaccharide-induced acute kidney injury is associated with down-regulation of the CYP2E1 gene

Effects of insulin treatment on hepatic CYP1A1 and CYP2E1 activities and lipid peroxidation levels in streptozotocin-induced diabetic rats

The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2-and Akt-dependent mechanism

CYP17A1 and CYP2E1 variants associated with high altitude polycythemia in Tibetans at the Qinghai-Tibetan Plateau

Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3

… of 95% khat ethanol extract (KEE) on human recombinant cytochrome P450 (CYP) 1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2 and CYP3A5

Genetic polymorphism of the drug-metabolizing enzyme Cytochrome P4502E1 (CYP2E1) in a healthy Saudi population

Oxidative stress caused by a SOD1 deficiency ameliorates thioacetamide-triggered cell death via CYP2E1 inhibition but stimulates liver steatosis

Synonymous mutation rs2515641 affects CYP2E1 mRNA and protein expression and susceptibility to drug-induced liver injury

Increased Expression of CYP2E1 gene in gastric cancer may be a molecular marker for mazandaran province population

Relative contributions of CYP1A2 and CYP2E1 to the bioactivation and clearance of 4-aminobiphenyl in adult mice

CYP2E1, oxidative stress, post-translational modifications and lipid metabolism

CYP2E1 RsaI and 96-bp insertion genetic polymorphisms associated with risk for colorectal cancer

… stem cells rescue rat hippocampal cells from aluminum oxide nanoparticle-induced apoptosis via regulation of P53, Aβ, SOX2, OCT4, and CYP2E1

High-Risk HPV with Multiple Infections Promotes CYP2E1, Lipoperoxidation and Pro-Inflammatory Cytokines in Semen of Asymptomatic Infertile Men

Covalent modification and time-dependent inhibition of human CYP2E1 by the meta-isomer of acetaminophen

Impact of CYP2E1, GSTA1 and GSTP1 gene variants on serum alpha glutathione S-transferase level in patients undergoing anaesthesia

Effects of Flavonoids in Lysimachia clethroides Duby on the Activities of Cytochrome P450 CYP2E1 and CYP3A4 in Rat Liver Microsomes

Involvement of CYP2E1 in the course of brain edema induced by subacute poisoning with 1, 2-Dichloroethane in mice

Garlic oil alleviated ethanol-induced fat accumulation via modulation of SREBP-1, PPAR-α, and CYP2E1

DNA damage in peripheral blood lymphocytes and association with polymorphisms in the promoter region of the CYP2E1 gene in alcoholics from Central Brazil

CYP2E1 RsaI/PstI polymorphism and liver cancer risk among east Asians: a HuGE review and meta-analysis

Inhibition of CYP2E1 With Propylene Glycol Does Not Protect Against Hepatocellular Injury in Human Acetaminophen Daily‐Dosing Model

Ferric citrate CYP2E1-independently promotes alcohol-induced apoptosis in HepG2 cells via oxidative/nitrative stress which is attenuated by pretreatment with …

Functional PstI/RsaI polymorphisms in the CYP2E1 gene among south Indian populations

Interactions between CYP2E1 and CYP2B4: effects on affinity for NADPH-cytochrome P450 reductase and substrate metabolism

… quantification of metabolic reaction products catalysed by CYP2E1 enzyme activity: inhibitory effect of cytochrome P450 enzyme CYP2E1 by salicylic acid in rat liver …

Genetic variation of ABCB1 (rs1128503, rs1045642) and CYP2E1 rs3813867 with the duration of tuberculosis therapy: a pilot study among tuberculosis …

Lrp6 Genotype affects Individual Susceptibility to Nonalcoholic Fatty Liver Disease and Silibinin Therapeutic Response via Wnt/β-catenin-CYP2E1 Signaling

RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure

The polymorphism rs2480258 within CYP2E1 is associated with different rates of acrylamide metabolism in vivo in humans

Quercetin prevents type 1 diabetic liver damage through inhibition of CYP2E1

Protective effect of Ornithogalum saundersiae Ait (Liliaceae) against acetaminophen-induced acute liver injury via CYP2E1 and HIF-1α

Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism

RsaI but not DraI polymorphism in CYP2E1 gene increases the risk of gastrointestinal cancer in Malaysians: a case–control study

Interactions between CYP2E1, GSTZ1 and GSTT1 polymorphisms and exposure to drinking water trihalomethanes and their association with semen quality

Epilobium hirsutum alters xenobiotic metabolizing CYP1A1, CYP2E1, NQO1 and GPx activities, mRNA and protein levels in rats

Association of GSTM1, GSTT1, GSTP1 and CYP2E1 single nucleotide polymorphisms with colorectal cancer in Iran

Human CYP2E1-dependent mutagenicity of mono-and dichlorobiphenyls in Chinese hamster (V79)-derived cells

The Inhibition Effect of the Seaweed Polyphenol, 7-Phloro-Eckol from Ecklonia Cava on Alcohol-Induced Oxidative Stress in HepG2/CYP2E1 Cells

CYP2E1 testis expression and alcohol-mediated changes of rat spermatogenesis indices and type I collagen

π–π Stacking mediated drug–drug interactions in human CYP2E1

Modulation of mRNA expression and activities of xenobiotic metabolizing enzymes, CYP1A1, CYP1A2, CYP2E1, GPx and GSTP1 by the Salicornia freitagii extract in …

Pretreatment with turmeric modulates the inhibitory influence of cisplatin and paclitaxel on CYP2E1 and CYP3A1/2 in isolated rat hepatic microsomes

Characterization of polymorphisms of genes ADH2, ADH3, ALDH2 and CYP2E1 and relationship to the alcoholism in a Colombian population

Correlation between spermatogenesis disorders and rat testes CYP2E1 mRNA contents under experimental alcoholism or type I diabetes

Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats

CYP2E1 polymorphism, acetylator profiles and drug-induced liver injury incidence of Indonesian tuberculosis patients

Aspartame administration and insulin treatment altered brain levels of CYP2E1 and CYP3A2 in streptozotocin-induced diabetic rats

Increased oxidative stress and toxicity in ADH and CYP2E1 overexpressing human hepatoma VL-17A cells exposed to high glucose

Targeted delivery of CYP2E1 recombinant adenovirus to malignant melanoma by bone marrow-derived mesenchymal stem cells as vehicles

Effects of ethanol on CYP2E1 levels and related oxidative stress using a standard balanced diet

Genotype-Environment Interaction Analysis of NQO1, CYP2E1, and NAT2 Polymorphisms and the Risk of Childhood Acute Lymphoblastic Leukemia: A …

Polymorphisms in CYP2E1, GSTM1 and GSTT1 and anti-tuberculosis drug-induced hepatotoxicity

Effect of eurycomanone on cytochrome P450 isoforms CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2E1 and CYP3A4 in vitro

CYP2E1 genetic polymorphism with dietary, tobacco, alcohol habits, H. pylori infection status and susceptibility to stomach cancer in Mizoram, India

Caralluma umbellata Haw. protects liver against paracetamol toxicity and inhibits CYP2E1

CYP2E1 rs2031920, COMT rs4680 polymorphisms, cigarette smoking, alcohol use and lung cancer risk in a Japanese population

Genetic variations in the drug metabolizing enzyme, CYP2E1, among various ethnic populations of Pakistan

Persimmon vinegar and its fractions protect against alcohol-induced hepatic injury in rats through the suppression of CYP2E1 expression

… experimental and theoretical study of ROS scavenging by organosulfur compounds from garlic: In silico analysis of metabolic pathways and interactions on CYP2E1

Cytochrome P450 genes (CYP2E1 and CYP1A1) variants and susceptibility to chronic hepatitis B virus infection

Does CYP2E1 RsaI/PstI polymorphism confer head and neck carcinoma susceptibility?: A meta-analysis based on 43 studies

… -2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2

Association of mitochondrial deoxyribonucleic acid mutation with polymorphism in CYP2E1 gene in oral carcinogenesis

Liver cancer-related gene CYP2E1 expression in HBV transgenic mice with acute liver injury

Evolution of camel CYP2E1 and its associated power of binding toxic industrial chemicals and drugs

Mannan‐binding lectin attenuates acetaminophen‐induced hepatotoxicity by regulating CYP2E1 expression via ROS‐dependent JNK/SP1 pathway

Frequency distribution of high risk alleles of CYP2C19, CYP2E1, CYP3A4 genes in Haryana population

CYP2E1 T7632A and 9-bp insertion polymorphisms and colorectal cancer risk: a meta-analysis based on 4,592 cases and 5,918 controls

Comparing the protective effects of three sulfur compounds against acrylonitrile-induced acute toxicity in CYP2E1-induced rats

CYP2C8 and CYP2E1 genetic variants increase risk of tuberculosis in northwest Chinese Han population

Polymorphisms in the CYP2E1 and GSTM1 Genes as Possible Protection Factors for Leprosy Patients

Mutagenic Activity of N‐Nitrosodiethylamine in Cell Lines Expressing Human CYP2E1—Adequacy of Dimethylsulfoxide as Solvent

Identification of 2-piperidone as a biomarker of CYP2E1 activity through metabolomic phenotyping

A Systematically Combined Genotype and Functional Combination Analysis of CYP2E1, CYP2D6, CYP2C9, CYP2C19 in Different Geographic Areas of …

Association between genetic variants in CYP2E1 and CTRC genes and susceptibility to alcoholic pancreatitis: A systematic review and meta-analysis

Direct sequencing and comprehensive screening of genetic polymorphisms on CYP2 family genes (CYP2A6, CYP2B6, CYP2C8, and CYP2E1) in five ethnic …

Changes in coumarin kinetics and subcellular localization of CYP2E1 contribute to bile duct damage and reduce hepatocellular damage after repeated administration …

Ultrasensitive quantification of the CYP2E1 probe chlorzoxazone and its main metabolite 6-hydroxychlorzoxazone in human plasma using ultra performance liquid …

Human CYP2E1-dependent and human sulfotransferase 1A1-modulated induction of micronuclei by benzene and its hydroxylated metabolites in Chinese hamster …

Age-dependent features of CYP3A, CYP2C, and CYP2E1 functioning at metabolic syndrome

Association of CYP2E1 and NAT2 polymorphisms with lung cancer susceptibility among Mongolian and Han populations in the Inner Mongolian region

Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors

In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV …

N-Hydroxylation of 4-Aminobiphenyl by CYP2E1 Produces Oxidative Stress in a Mouse Model of Chemically Induced Liver Cancer

Investigation of CYP2E1 and Caspase-3 Gene Expressions in COVID-19 patients

How mutations affecting the ligand-receptor interactions: a combined MD and QM/MM calculation on CYP2E1 and its two mutants

Over-expression of CYP2E1 mRNA and protein: implications of xenobiotic induced damage in patients with de novo acute myeloid leukemia with inv (16)(p13. 1q22); …

CYP2E1 and GSTM1 gene polymorphisms, environmental factors, and the susceptibility to lung cancer

Susceptibility to the acute toxicity of acrylonitrile in streptozotocin-induced diabetic rats: protective effect of phenethyl isothiocyanate, a phytochemical CYP2E1 …

Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and CYP2E1 expression levels

4-Fluoromethamphetamine (4-FMA) induces in vitro hepatotoxicity mediated by CYP2E1, CYP2D6, and CYP3A4 metabolism

In-Vitro CYP3A4, CYP2E1 and UGT activity in human liver microsomes by Strobilanthes crispus leaf extracts

Red meat intake, CYP2E1 and PPARγ polymorphisms, and colorectal cancer risk

The effects of non-esterified fatty acids and β-hydroxybutyrate on the hepatic CYP2E1 in cows with clinical ketosis

Association of GSTM1, GSTT1 and CYP2E1 gene polymorphisms with antituberculosis drug induced hepatotoxicity in North Indian population

Contributions of caspase-8 and-9 to liver injury from CYP2E1-produced metabolites of halogenated hydrocarbons

Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells overexpressing CYP2E1

Crosstalk between CYP2E1 and PPARα substrates and agonists modulate adipose browning and obesity

CYP2E1 inhibition and NF_κB Signaling Pathway are Involved in the Protective Molecular Effect of Origanum floribundum against Acetaminophen-induced …

The polymorphism of CYP2E1 Rsa I/Pst I gene and susceptibility to respiratory system cancer: a systematic review and meta-analysis of 34 studies

Association analysis of SNPs in the porcine CYP2E1 gene with skatole, indole, and androstenone levels in backfat of a crossbred pig population

Fermented Curcuma longa L. Prevents Alcoholic Fatty Liver Disease in Mice by Regulating CYP2E1, SREBP-1c, and PPAR-α

Structure-toxicity relationship study of para-halogenated styrene analogues in CYP2E1 transgenic cells

1, 3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice

CYP2E1 gene rs6413420 polymorphism was first found in the Bouyei ethnic group of China

Chemical characteristics for optimizing CYP2E1 inhibition

Hepatoprotective effect of 10% ethanolic extract from Curdrania tricuspidata leaves against ethanol-induced oxidative stress through suppression of CYP2E1

Association between CYP2E1 and GOT2 gene polymorphisms and susceptibility and low-dose N, N-dimethylformamide occupational exposure-induced liver injury

A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma

Novel CYP2E1 haplotype identified in a South African cohort

Adrenergic blocker terazosin potentially suppresses acetaminophen induced-acute liver injury in animal models via CYP2E1 gene

Human CYP2E1‐dependent mutagenicity of benzene and its hydroxylated metabolites in V79‐derived cells: Suppression and enhancement by ethanol pretreatment

Vitamin E in vivo studies on the activity of antioxidant enzymes and CYP2E1 expression in high PUFA-treated brains

Identification of cytochrome CYP2E1 as critical mediator of alcohol effects on steatotic hepatocytes

A study on the optimization of CYP2E1 enzyme activity in C57Bl/6 mouse brain and liver

Chemoprotective Effect of Daphnetin Against Benzene-induced Leukemia via Alteration of CYP2E1

Contribution of CYP2E1 polymorphism to aging in the mechanical workshop workers

Ethanol-induced oxidative stress modifies inflammation and angiogenesis biomarkers in retinal pigment epithelial cells (ARPE-19): role of CYP2E1 and its inhibition …

The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65

… effect of seed coat ofEuryale ferox extract in non-alcoholic fatty liver disease induced by high-fat diet in mice by increasing IRs-1 and inhibiting CYP2E1

Kaempferol’s protective effect on ethanol-induced mouse primary hepatocytes injury involved in the synchronous inhibition of SP1, Hsp70 and CYP2E1

Targeted CYP2E1 quantification and its correlation to currently acceptable clinical biochemical indices

Research on the progress of alcoholic liver disease pathogenesis related to CYP2E1

Effect of jujube on the expression of CYP2E1 and TNF-alpha in the hepatic tissue of mice with alcoholic liver disease

Establishment of a p-nitrophenol oxidation-based assay for the analysis of CYP2E1 activity in intact hepatocytes in vitro

No association of CYP2E1 genetic polymorphisms with alcohol dependence in Han Taiwanese population

Roles of CYP1A1 and CYP2E1 gene polymorphisms in Oral submucous fibrosis

Significant genotype difference in the CYP2E1 PstI polymorphism of indigenous groups in Sabah, Malaysia with Asian and non-Asian populations

Camelus dromedarius putative cytochrome P450 enzyme CYP2E1: complete coding sequence and phylogenetic tree

Alteration of CYP2E1, DBN1, DNMT1, miRNA-335, miRNA-21, c-Fos and Cox-2 gene expression in prefrontal cortex of rats’ offspring submitted to prenatal ethanol …

Effect of water miscible organic solvents on p-nitrophenol hydroxylase (CYP2E1) activity in rat liver microsomes

Updated meta-analysis of the association between CYP2E1 RsaI/PstI polymorphisms and lung cancer risk in Chinese population

Transgenic plant regeneration of tobacco (Nicotiana tabacum) haboring mammalian CYP2E1 gene

Relationship of ALDH2 rs671 and CYP2E1 rs2031920 with hepatocellular carcinoma susceptibility in East Asians: a meta-analysis

Effect of BI-1 on insulin resistance through regulation of CYP2E1

Propolis alleviates 4‐aminobiphenyl‐induced oxidative DNA damage by inhibition of CYP2E1 expression in human liver cells

Protective effects of garlic oil against 1, 3-dichloro-2-propanol-induced hepatotoxicity: Role of CYP2E1 and MAPKs

Pyridoxine deficiency modulates benzene inhalation-induced hematotoxicity associated with hepatic CYP2E1 activity in B6C3F1 mice

Polymorphisms in alcohol dehydrogenase (ADH1) and cytochrome p450 2E1 (CYP2E1) genes in patients with cirrhosis and/or hepatocellular carcinoma

CYP2E1: the anesthesia enzyme

Meta-analysis of CYP2E1 polymorphisms in liver carcinogenesis

Pharmacological blockage of CYP2E1 and alcohol-mediated liver cancer: is the time ready?

CYP2E1 RsaI/PstI polymorphisms contributed to oral cancer susceptibility: a meta-analysis

Note of clarification of data on the association between CYP2E1 RsaI polymorphism and lung cancer risk

Environmental exposure to benzene: evaluation of urinary S-PMA and polymorphism (CYP2E1-1293G> C and NQO1 609C> T) in Campos Elíseos residents …

Dietary omega-3 polyunsaturated fatty acids alter fatty acid composition of lipids and CYP2E1 expression in rat liver tissue

CYP2E1 and ALDH2 gene polymorphisms in squamous cell head and neck Cancer in the Turkish population

Plasma cholinesterase activity is influenced by interactive effect between omethoate exposure and CYP2E1 polymorphisms

Study on inhibitory effect of water extract of Polygonum multiflorum on CYP1A2 and CYP2E1 enzymatic activities and mRNA expressions in rat liver

Effects of aqueous extract of Polygoni Multiflori Radix and its main constituents on expression of mRNA of CYP1A2, CYP2C9, and CYP2E1 in human liver L02 cells

Association between CYP2E1 genetic polymorphisms and urinary cancer risk: a meta-analysis

mRNA Expression of CYP2E1, CYP2A19, CYP1A2, HSD3B, SULT1A1 and SULT2A1 genes in surgically castrated, immunologically castrated, entire male and female …

Investigation of cytochrome p450 CYP1A2, CYP2D6, CYP2E1 and CYP3A4 gene expres-sions and polymorphisms in alcohol with-drawal

2‐mercaptobenzothiazole generates γ‐H2AX via CYP2E1‐dependent production of reactive oxygen species in urothelial cells

CYP2E1-and TNFalpha/LPS-induced oxidative stress and MAPK signaling pathways in alcoholic liver disease

Study of CYP2E1 gene RsaI/PstI polymorphisms in patients with gastric cancer in north of Iran

Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity

Quantification of CYP2E1 in rat liver by UPLC-MS/MS-based targeted proteomics assay: a novel approach for enzyme activity assessment

Mechanism and clinical significance of HBx-mediated inhibition of CYP2E1 expression in the human HepG2 hepatoma cell line

Differences in butadiene adduct formation between rats and mice not due to selective inhibition of CYP2E1 by butadiene metabolites

Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells

Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients

Induction of rat hepatic CYP2E1 expression by arecoline in vivo

Ethanol-induced CYP2E1 Expression is Reduced by Lauric Acid via PI3K Pathway in HepG2 Cells

The physiological mechanism of improved formaldehyde resistance in Petunia hybrida harboring a mammalian CYP2E1 gene

Obesity‐induced CYP2E1 activity in children

CYP2E1, GSTM1, and GSTT1 genetic polymorphisms and their associations with susceptibility to antituberculosis drug-induced liver injury in Thai …

Mammalian CYP2E1 gene triggered changes of relative ions fluxes, CaM content and genes expression profiles in Petunia hybrida cells to enhance resistance to …

Losartan effects on liver cytochromes CYP3A, CYP2C and CYP2E1 functioning at metabolic syndrome in young and adult rats

All trans retinoic acid modulates TNF-α and CYP2E1 pathways and enhances regression of ethanol-induced fibrosis markers in hepatocytes and HSCs in abstaining …

CYP2E1 and Parkinson’s disease in a MPTP-induced C57BL/6 mouse model

End-product inhibition of skatole-metabolising enzymes CYP1A, CYP2A19 and CYP2E1 in porcine and piscine hepatic microsomes

ZSCAN25 and CYP2E1 polymorphisms is risk factors for ischemic stroke in a Chinese Han population: a case control study

CYP2E1 activity and children with obesity: possible confounding factors

Effects of SNPs (CYP1B1* 2 G355T, CYP1B1* 3 C4326G, and CYP2E1* 5 G-1293C), smoking, and drinking on susceptibility to laryngeal cancer among Han …

Exogenous toluene gas removal improvement in recombinant rabbit cytochrome P450 2E1 (CYP2E1)-transgenic Ardisia pusilla DC

CYP2E1 polymorphisms and colorectal cancer

Cytochrome P450 CYP2E1 Suppression Ameliorates Cerebral Ischemia Reperfusion Injury. Antioxidants 2021, 10, 52

Association of CYP2E1 and CYP1A1m2 (BsrD1) polymorphisms with cytogenetic biomarkers in petrol pump workers

Ephedra water decoction and cough tablets containing ephedra and liquorice induce CYP1A2 but not CYP2E1 hepatic enzymes in rats

Association of CYP1A1 and CYP2E1 gene polymorphisms with prostate cancer in a Lebanese population

Anti-tuberculosis drug-induced liver injury correlated with the methylation in the promoter regions of CYP2E1 and GSTM1

Unraveling CYP2E1 haplotypes in alcoholics from Central Brazil: a comparative study with 1000 genomes population

The effects of bovine serum albumin on kinetic characterization of human liver microsomal CYP2C19 and CYP2E1 activities

The effect of changes in CYP2E1 activity in the liver on toxicity and carcinogenicity of diethylnitrosamine in mice

Association of radiation risk in the second and third generations with polymorphisms in the genes CYP1A1, CYP2E1, GSTP1 and changes in the thyroid

Correction to: CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes

Modulation of CYP2E1 metabolic activity in a cohort of confirmed caffeine ingesting pregnant women with preterm offspring

M1 Polarization bias and subsequent NASH progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1 induced oxidative stress in …

Effect of Dietary Supplementation with Dried Tuber of Jerusalem Artichoke on Skatole Level in Backfat and CYP2E1 mRNA Expression in Liver of Boars

Roles of CYP2E1 in liver damage induced by 1, 2-dichloroethane

An improved in vitro method for screening toxin and medicine targeting CYP2E1

… : Nanoformulated SOD1 ameliorates the combined NASH and alcohol-associated liver disease partly via regulating CYP2E1 expression in adipose tissue and …

The Association of CYP2E1 Polymorphism and Environmental Factor in Nasopharyngeal Carcinoma Patients

Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?

Effect of Er Chen Tang on CYP2E1 and mitochondrial energy metabolism in nonalcoholic fatty liver disease

Requirement prediction for toluene detox with foods intake rich in CYP2E1 enzyme and glycine to prevent nerve and kidney damage at shoe home industry …

Association of CYP1A1 and CYP2E1 gene polymorphism with risk of arsenism caused by coal-burning

Insights into insulin-mediated regulation of CYP2E1: miR 132/212 targeting of CYP2E1 and role of PI3-K, Akt, mTOR signaling in regulating miR132/212 and miR 122 …

Polymorphisms of CYP2E1 rs2031920 is not Associated with Risk of Nasopharyngeal Carcinoma in Minangkabau Ethnic Group

Silver Nanoparticle-Doped Poly (8-Anilino-1-Naphthalene Sulphonic Acid)/CYP2E1 Nanobiosensor for Isoniazid-A First Line Anti-Tuberculosis Drug

Correlation between genetic polymorphisms of CYP2E1 DraⅠ and susceptibility of gastric cancer in Qinghai province

Genotype and phenotype polymorphisms of NAT2 and CYP2E1 in the Han Chinese pediatric population

Identification of Novel CYP2E1 Inhibitor to Investigate Cellular and Exosomal CYP2E1-Mediated Toxicity

Lack of association of CYP2E1 and CYP1A1 polymorphisms with osteoporosis in postmenauposal women

TRPV4 attenuates M1 polarization and subsequent NASH progression by stalling CYP2E1-mediated redox toxicity via eNOS.

Comment on:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”

Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like

Association between the TP53 and CYP2E1* 5B gene polymorphisms and non-small cell lung cancer

THE ROLE OF CYP2E1 POLYMORPHISM IN THE ACTIVATION OF PROCARCINOGEN METABOLISM OF NASOPHARYNGEAL CARCINOMA

CYP2E1 immunoglobulin G4 subclass antibodies after desflurane anesthesia

Effect of Capsosiphon fulvescens on ethanol-induced liver damage in HepG2 cells over expressing CYP2E1

Effect of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos before and after compatibility on activities of CYP1A2, CYP2E1, and CYP3A4 from rat liver …

Chemoprotective Effect of Daphnetin against Benzene Induced Leukemia Cancer via Alteration of CYP2E1

Modulatory effects of persimmon vinegar and its fractions on hepatic immune response and CYP2E1 activation in chronically alcohol drinking rats (649.4)

Ekspresija CYP2E1 u testisima štakora i alkoholom prouzrokovane promjene indeksa spermatogeneze i kolagena tipa I

Alcohol-Induced Increase in the Content of CYP2E1 in Human Liver Microsomes Causes a Multifold Activation of CYP3A4 and Attenuates its Cooperativity

CYP2E1 Associated Dysregulation of Nucleotide Excision Repair (NER) Process In Hepatocellular Carcinoma

Heliotropium undulatum attenuates hydrazine induced hepatotoxicity: involvement of cytochrome P450 CYP2E1 and oxidative stress

Maternal protein restriction during lactation modulated the expression and activity of rat offspring hepatic CYP1A1, CYP1A2, CYP2B1, CYP2B2, and CYP2E1 …

In Silico Approach for Hepatoprotective Activity of Piper crocatum Leaf Towards CYP2E1 Protein:(TJPS-2020-0154. R2)

Chronic ethanol and high glucose inducible CYP2E1 mediated oxidative stress leads to greater cellular injury in VL-17A cells: a potential mechanism for liver injury …

Extracts of Poria cocos polysaccharides improves alcoholic liver disease in mice via CYP2E1 and NF-κB inflammatory pathways

Liver Tissue-specific Genes IGFALS, CYP3A4, SLC22A1 and CYP2E1 May be Associated with Poor Prognosis of Liver Cancer

CYP2E1-DEPENDENT VARIATIONS IN HEPATOCYTES DAMAGE DURING TREATMENT OF TUBERCULOSIS

Higher CYP2E1 activity is a risk factor for hepatocarcinogenesis

Expression of CYP2E1 in different brain regions during the formation of toxic cerebral edema induced by 1, 2-DCE in mice and its effect on cerebral edema formation

Cloning and bioinformatics revealed molecular characterisation of CYP2E1 gene from bactrian camel (Camelus bactrianus)

Hepatotoxicity Risk Profile of Indonesian Due to Polymorphism of NAT2 and CYP2E1 in Isoniazid Metabolism

The Polymorphism and Expression of CYP2E1 Gene and Its Relation to Carcass and Meat Quality of Indonesian Lamb

The regulation of CYP2E1 gene expression and its role in breast cancer

Effect of grapefruit juice on CYP2E1 gene expression in obese and control rats

CYP2E1 mediated ethanol metabolism in ARPE-19 cells.

Correction: Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis

Non-additive effects of changing the cytochrome P450 ensemble: incorporation of CYP2E1 into human liver microsomes and its impact on CYP1A2

The correlation between CYP2E1 and CYP1A1 genotypes with the susceptibility of HBV infection in northern Guangzhou people

COMPARISON OF POLYMORPHISM rs2070672 CYP2E1 GENE PROPORTION IN EARLY AND ADVANCED STAGE OF UNDIFFERENTIATED TYPE …

Crosstalk between CYP2E1 and CYP3A enzymes and its Possible Involvement in Alcohol-Drug Interactions.

MicroRNA‐122 protects mice and human hepatocytes from acetaminophen toxicity by regulating CYP1A2 and CYP2E1 expression

Evaluation of smoke burning AnbarNesara on changes of the gene expression of P53 and CYP2E1 in human liver cancer cells

Profile of retinal pigment epithelium response to ethanol: Role of CYP2E1

CYP2E1 activity on ARPE-19 cells: New approach to RPE ethanol metabolism

Povezanost polimorfizama gena TP53 i CYP2E1* 5B s nemikrocelularnim karcinomom pluća

Relationship between CYP2E1 genetic polymorphism and susceptibility of gastric cancer in Hakkaness

Bioinformatic Analysis of the Main Characteristics and Structure of the Gene Encoding CYP2E1 Protein.

Response: Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?

… Protects Hepato-Renal Tissues Against Antituberculosis Drugs Induced Toxic Manifestations by Modulating IL-6, IGF-1, CYP2E1, Biochemical and Ultra …

Expression of CYP2E1 gene in paint workers occupationally exposed to organic solvents

Results of intensive phase tretament of tuberculosis treatment according to CYP2E1 genotype

Association of CYP2E1 Gene Polymorphisms with the Risk of Schizophrenia in the Bangladeshi Population

Expression of CYP2E1 gene in paint workers occupationally exposed to organic solvents

Enhanced Hepatotoxicity of Extract of Polygoni Multiflori Radix after Inhibition of CYP2E1 and Screening of Toxic Constituents

CYP2E1 recovery is associated with a pericentral fibrosis pattern after repeated CCl4 insults

Polymorphisms of CYP2E1 rs2031920 is not Associated with Risk of Nasopharyngeal Carcinoma in Minangkabau Ethnic Group. Open Access Maced J Med Sci …

CYP2E1 activity in cisplatin resistant cancer cells

Effect of temperature on carp CYP2E1-like isoform activity.

The Meta Isomer of Acetaminophen Is A Time Dependent Inhibitor of Human CYP2E1

CYP2E1 substrate inhibition. MECHANISTIC INTERPRETATION THROUGH AN EFFECTOR SITE FOR MONOCYCLIC COMPOUNDS.

The Oxidative Effect Of Nlrp3 And CYP2E1 In Development Of Renal Failure Associated With Hypertension And Diabetes Mellitus Diseases

UPREGULATING OF CYP2E1 IN ETHANOL-FED MICE WITH TRANSGENIC OVEREXPRESSION OF CTRP3

Distribution of single nucleotide polymorphisms of CYP2E1 gene in Congjiang Xiang-pigs.

Genetic Polymorphism in Promoter Sequence of CYP2E1 Gene in Paint Manufacturing Workers Exposed to Volatile Organic Compounds

Computational Docking Simulations of Nitroanisole and Nitrophenol with CYP2E1

TRPV4 Modulates CYP2E1 Function in Nonalcoholic Steatohepatitis Progression

Genotype and allelic frequencies of CYP2E1* 5B polymorphism in the southwest population of Iran

Effects of trichloroethylene toxicity on normal human liver cells and hepatocytes with CYP2E1 gene overexpression

Assessing specificity of indazole derivatives as inhibitors to CYP2E1

Effects of three kinds of tea beverages on intestinal first-pass effect and liver Cyp3a, CYP2E1 activities in mice

Nicotinamide N-Oxidation by CYP2E1 in Human Liver Microsomes

Association of genetic polymorphisms of CYP2E1 and MPO genes with acute leukemia risk: a meta-analysis.

Effect of Jiangzhiligan Granules on CYP2E1 Gene and Protein Expression of Rat Model with Non-alcoholic Fatty Liver Disease

Identification of deletions and duplications in the CYP2E1 gene in a population in Goiânia–GO by MLPA.

Effects of Mailuoning injection on rat activities of CYP1A2, CYP2E1 and CYP3A4 using a three-drug Cocktail approach

Requirement Prediction for Toluene Detox with Foods Intake Rich in CYP2E1 Enzyme and Glycine to Prevent Nerve and Kidney Damage at Shoe Home …

CYP2E1 Epigenetic Regulation In Workers Exposed To Low-Level Voc Mixture: Relationship With Nitrosative Stress And Inflammation

The Inhibitory Effect of the Derris scandens Extract on Cytochrome P450 2E1 (CYP2E1)-associated Aniline-4-Hydroxylase in vitro

Association of CYP2E1 and CYP1A1m2 (BsrD1) polymorphisms with cytogenetic biomarkers in petrol pump workers

The Physiological Mechanism of Petunia hybrida Harboring Mammalian CYP2E1 Gene Improving Resistance to Formaldehyde

Non‐Additive Effects of Changing the Composition of the Cytochrome P450 Ensemble in Human Liver Microsomes: the Focus on CYP2E1 and Alcohol‐Drug …

Higher chlorzoxazone clearance in obese children compared with none-obese peers, an open-label explorative pharmacokinetic study of CYP2E1 activity

Cytochrome CYP2E1 is critical for joint effects of alcohol and lipids on hepatocellular steatosis and inflammation

CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population

A study on the effects of Lauric acid on ROS formation and CYP2E1 mRNA expression in alcohol-induced HEPG2 cells

Research on Association of Genetic Polymorphism of CYP1A1 and CYP2E1, with Susceptibility to Gastric Cancer

CYP2E1 VNTR genotyping associated to anti–tuberculosis drug-induced hepatotoxicity

Study on CYP2E1 gene polymorphism and the relationship between methylation level of its promoter region and liver injury induced by anti-tuberculosis drugs in …

Relative contribution of hepatic CYP3A and CYP2E1 to oxidative stress upon CHIP E3 ligase knockdown

Effect of Neiyixiao on Hepatic CYP1A2, CYP2E1, CYP3A4 in Rats with Endometriosis

Bioinformatics of CYP2E1 CpG intron methylation sites and application to HAR1-RELN sequence analysis

Effect of flavonoids extract from apocynum venetum tea on CYP2E1 in mice.

CYP2E1 is a central mediator for the synergistic effects of alcohol and free fatty acids on hepatocellular steatosis and inflammation

Acetaminophen and Isoniazid treatment leads to oxidative stress and cytotoxicity in cerebellar granule neurons possibly by CYP2E1 activation

Drinking Water Chlorination By-Products and Intra-Uterine Growth Restriction: is there an effect modification of the CYP2E1 G1259C gene polymorphism?

CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis

Study the Correlation of GSTM1 and CYP2E1 Gene Polymorphism and Genetic Susceptibility to Non-small Cell Lung Cancer in Shenzhen Area

CONTROL OF BOAR TAINT BY USING GENETIC MARKERS: A SINGLE NUCLEOTIDE POLYMORPHISM IN THE CYP2E1 GENE PROMOTER AFFECTS …

Binge alcohol promotes acute liver injury through a CYP2E1‐HIF‐1α‐dependent apoptosis pathway in mice and humans (1010.1)

Effects of cefetamet hydrochloride injection on activity of CYP1A2, CYP3A4 and CYP2E1 in liver microsomes of rats

Evaluation of genotoxicity of environmental contaminants, production of bio-sensor cell lines and measurment of CYP2E1 enzymatic activity

B107 TUBERCULOSIS: ISSUES DURING TREATMENT: An Updated Meta-Analysis On CYP2E1 Rsai/psti And Drai Polymorphisms And Risk Of Anti-Tuberculosis …

An Updated Meta-Analysis On CYP2E1 RsaI/PstI And DraI Polymorphisms And Risk Of Anti-Tuberculosis Induced Hepatotoxicity: Evidence From 26 Studies

Analysis of Protein and mRNA Expressions of CYP1A1 and CYP2E1 Enzymes In Liver, Colon And Prostate Cancer Cell Lines to Study Drug and Carcinogen …

Correction: Investigation of Indazole Unbinding Pathways in CYP2E1 by Molecular Dynamics Simulations

Polimorfismos nos genes NAT2, CYP2E1, GSTT1, GSTM1 e ABCB11 e hepatotoxicidade induzida pela isoniazida

GENOTYPE POLYMORPHISMS OF NAT2 AND CYP2E1 GENES ASSOCIATED WITH DRUG INDUCED LIVER INJURY (DILI) IN INDONESIAN …

Effects of nonyphenol exposure during pregnant and lactation period on expressions of CYP2E1 mRNA and protein of hepatic tissues in offspring rats.

Modulatory effects of persimmon vinegar and its fractions on alcohol-induced inflammatory stress and CYP2E1 expressions in the liver of Wistar rats

CYP2E1 rs2031920, COMT rs4680 Polymorphisms, Cigarette Smoking, Alcohol Use and Lung Cancer Risk in a Japanese Population

The role of brain acetaldehyde in drinking preference: Genetic modification of alcohol oxidizing enzymes catalase and CYP2E1 in C57BL/6 mice and their …

The effect of organic solvents and CYP1A1, CYP2E1, GSTM1 polymorphisms on the development of acute lymphoblastic leukemia in Quebec children

Nonclassical ROR Alpha Pathway Switches Transcriptional Mode of ERR Gamma that Results in Repression of Alcohol-induced CYP2E1 Expression

Effects of the plant phenolic quercetin on protein and mRNA CYP1A1, CYP2E1, NQO1 and GST enzymes in colon cancer cell line SW620

Analysis of protein and mRNA expressions of CYP1A1, CYP2E1, NQO1 and GST enzymes in liver, colon and prostate cancer cell lines to study drug and carcinogen …

Analysis of ethanol metabolic enzymes in primary human mammary epithelial cells and MCF‐10A cells: possible participation of CYP2E1 in ethanol‐induced oxidative …

Hepatoprotective Activity of Eugenol, Hesperidin and Lepidium Sativum Alkaloids in Rats with Liver Injury through Attenuating CYP2E1/Nuclear Factor Kappa-B and …

S29. 1 CORRELATION BETWEEN SPERMATOGENESIS DISORDERS AND CYP2E1 MRNA EXPRESSION IN RATS TESTES FOLLOWING CHRONIC …

ISALPDC-03: CYP2E1 Regulation of Ethanol-Induced Intestinal miRNAs in Liver Injury

Comparison of Polymorphism rs3813865 Cytochrome P450 Family 2 Subfamily E Polypeptide 1 (CYP2E1) Gene in Various Clinical Stage of Undifferentiated …

0466 The effect of SNPs in the promoter on expression of CYP2E1 gene and boar taint

Author’s Reply to Reith:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”

Regulation of il-1 and TNF-α on metabolic enzyme CYP2E1 in immunological liver injury in rats

… ALCOHOL AND CANCER SY05-1 CARCINOGENIC ETHENO DNA ADDUCTS GENERATED DURING INFLAMMATION AND CYP2E1 INDUCTION IN VARIOUS …

Author Correction: Effect of BI-1 on insulin resistance through regulation of CYP2E1

Correction to The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65

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