ANTI COVID-19 EFFECTS OF MEDICINAL PLANTS, FLAVONOIDS & POLYPHENOLS
January 10, 2021Insulin & Aging
February 5, 2021- … . Initial studies were promising (Miserendino et al 1990). Infusion of APV prior to learning blocked fear conditioning, but infusion proior to testing had no effect. NMDA
- … blockade of NMDA receptors induces epigenetic abnormalities in the adult medial prefrontal cortex: possible involvement in memory impairment in trace fear …
- … in rats is mediated by neurons in the deep layers of the superior colliculus/deep mesencephalic nucleus of the rostral midbrain through the glutamate non-NMDA …
- … of an NR2B-selective or an NR2A-preferring NMDA receptor antagonist differentially influence fear conditioning and expression in the fear-potentiated startle test
- A critical role for VEGF and VEGFR2 in NMDA receptor synaptic function and fear-related behavior
- A NMDA receptor antagonist, MK-801 impairs consolidating extinction of auditory conditioned fear responses in a Pavlovian model
- A risk variant for alcoholism in the NMDA receptor affects amygdala activity during fear conditioning in humans
- Acquisition of contextual Pavlovian fear conditioning is blocked by application of an NMDA receptor antagonist D, L-2-amino-5-phosphonovaleric acid to the …
- Acquisition of fear extinction requires activation of NR2B-containing NMDA receptors in the lateral amygdala
- Acquisition, extinction, and reinstatement of Pavlovian fear conditioning: the roles of the NMDA receptor and nitric oxide
- Activity-induced synaptic delivery of the GluN2A-containing NMDA receptor is dependent on endoplasmic reticulum chaperone Bip and involved in fear …
- Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear …
- Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase
- Amygdalar NMDA receptors are critical for new fear learning in previously fear-conditioned rats
- Amygdalar NMDA receptors are critical for the expression of multiple conditioned fear responses
- An appetitive experience after fear memory destabilization attenuates fear retention: involvement GluN2B-NMDA receptors in the Basolateral Amygdala Complex
- An appetitive experience after fear memory destabilization attenuates fear retention: involvement GluN2B-NMDA receptors in the Basolateral Amygdala Complex.
- An NMDA–receptor antagonist, MK-801 blocks the suppressive vasopressin response to fear-but not to anxiety-related stimuli in the rat.
- Aquaporin-4 deficiency facilitates fear memory extinction in the hippocampus through excessive activation of extrasynaptic GluN2B-containing NMDA receptors
- Are fear memories made and maintained by the same NMDA receptor-dependent mechanisms?
- ASIC1a regulates ventral hippocampal-infralimbic prefrontal plasticity and fear extinction via BDNF-NMDA receptor signaling
- Bed nucleus of the stria terminalis NMDA receptors and nitric oxide modulate contextual fear conditioning in rats
- Beyond attention: The role of amygdala NMDA receptors in fear conditioning
- Blockade of Cav2. 1-mediated NMDA receptor signaling disrupts conditioned fear extinction
- Blockade of NMDA receptors in the amygdala prevents latent inhibition of fear-conditioning
- Blocking of acquisition but not expression of conditioned fear-potentiated startle by NMDA antagonists in the amygdala
- Brief neonatal maternal separation alters extinction of conditioned fear and corticolimbic glucocorticoid and NMDA receptor expression in adult rats
- Close linkage between calcium/calmodulin kinase II α/β and NMDA‐2A receptors in the lateral amygdala and significance for retrieval of auditory fear conditioning
- Complex effects of NMDA receptor antagonist APV in the basolateral amygdala on acquisition of two-way avoidance reaction and long-term fear memory
- Conditioning-strength dependent involvement of NMDA NR2B subtype receptor in the basolateral nucleus of amygdala in acquisition of auditory fear memory
- Consolidation of auditory fear memories formed by weak unconditioned stimuli requires NMDA receptor activation and de novo protein synthesis in the …
- Consolidation of fear extinction requires NMDA receptor-dependent bursting in the ventromedial prefrontal cortex
- Decrease in NMDA receptor-signalling activity in the anterior cingulate cortex diminishes defensive behaviour and unconditioned fear-induced antinociception elicited …
- Differential involvement of amygdala and cortical NMDA receptors activation upon encoding in odor fear memory
- Differential involvement of amygdalar NMDA receptors across variants of contextual fear conditioning in adolescent rats
- Differential involvement of amygdalar NMDA receptors in variants of adolescent contextual fear conditioning
- Differentiating the contributions of NMDA receptor-mediated synaptic plasticity in basal and lateral nuclei of the amygdala during Pavlovian fear conditioning
- Dorsal hippocampus and classical fear conditioning to tone and context in rats: Effects of local NMDA‐receptor blockade and stimulation
- Dorsal hippocampus NMDA receptors differentially mediate trace and contextual fear conditioning
- Effect of the NMDA antagonist MK-801 on latent inhibition of fear conditioning
- Effects of agonists and antagonists of NMDA and ACh receptors on plasticity of bat auditory system elicited by fear conditioning
- Effects of an NMDA–receptor antagonist, MK-801 on emotional memory associated with neurohypophysial responses to fear or anxiety stimuli in rats
- Effects of NMDA receptor antagonists and sigma ligands on the acquisition of conditioned fear in mice
- Effects of REM deprivation and an NMDA agonist on the extinction of conditioned fear
- Effects of single prolonged stress and D-cycloserine on contextual fear extinction and hippocampal NMDA receptor expression in a rat model of PTSD
- Elucidating the mechanisms of fear extinction in developing animals: a special case of NMDA receptor-independent extinction in adolescent rats
- Endogenous co-agonists of the NMDA receptor modulate contextual fear in trace conditioning
- Estradiol-induced enhancement of fear extinction in female rats: The role of NMDA receptor activation
- Estradiol-induced enhancement of fear extinction in female rats: the role of NMDA receptor activation Running title: Estradiol, NMDAr activation, and fear …
- Extinction of fear-potentiated startle: blockade by infusion of an NMDA antagonist into the amygdala
- Extinction of fear-potentiated Startle: Blockade by Infusion of an NMDA Antagonist into the Amygdala
- fear conditioning performance and NMDA receptor subtypes: NR2A differential expression in the striatum
- fear memory extinction accelerated by simultaneous activation of GABA (B) and NMDA receptors
- fear memory impairing effects of systemic treatment with the NMDA NR2B subunit antagonist, Ro 25-6981, in mice: attenuation with ageing
- GABA and NMDA receptors in CRF neurons have opposing effects in fear acquisition and anxiety in central amygdala vs. bed nucleus of the stria terminalis
- Glutamate NMDA receptors within the amygdala participate in the modulatory effect of glucocorticoids on extinction of conditioned fear in rats
- Hippocampal NMDA receptor blockade impairs CREB phosphorylation in amygdala after contextual fear conditioning
- Hippocampal NMDA receptor subunits differentially regulate fear memory formation and neuronal signal propagation
- Hippocampal NMDA receptors are necessary for auditory trace fear conditioning measured with conditioned hypoalgesia in rats
- Hypofunction of the dorsal hippocampal NMDA receptors impairs retrieval of memory to partially presented foreground context in a single-trial fear conditioning in rats
- Impairment of conditioned contextual fear of C57BL/6J mice by intracerebral injections of the NMDA receptor antagonist APV
- Induction-and conditioning-protocol dependent involvement of NR2B-containing NMDA receptors in synaptic potentiation and contextual fear memory in the …
- Infusion of the NMDA receptor antagonist, DL-APV, into the basolateral amygdala disrupts learning to fear a novel and a familiar context as well as relearning to fear …
- Infusion of the non-NMDA receptor antagonist CNQX into the amygdala blocks the expression of fear-potentiated startle
- Injections of the NMDA receptor antagonist aminophosphonopentanoic acid into the lateral nucleus of the amygdala block the expression of fear-potentiated startle …
- Interaction between glutamatergic–NMDA and cholinergic–muscarinic systems in classical fear conditioning
- Intra-amygdala blockade of the NR2B subunit of the NMDA receptor disrupts the acquisition but not the expression of fear conditioning
- Involvement of NMDA receptors within the amygdala in short-versus long-term memory for fear conditioning as assessed with fear-potentiated startle.
- Lack of a temporal gradient of retrograde amnesia following NMDA-induced lesions of the basolateral anygdala assessed with the fear-potentiated startle paradigm.
- Latent inhibition of cued fear conditioning: an NMDA receptor‐dependent process that can be established in the presence of anisomycin
- Loss of NMDA receptor function in corticotrophin-releasing factor neurons sex-dependently enhances fear and increases sensitivity to social stress, yet reduces social …
- Mapping and deciphering neural codes of NMDA receptor-dependent fear memory engrams in the hippocampus
- Neonatal ethanol exposure impairs trace fear conditioning and alters NMDA receptor subunit expression in adult male and female rats
- Neonatal treatment with a competitive NMDA antagonist results in response-specific disruption of conditioned fear in preweanling rats
- Newly acquired and reactivated contextual fear memories are more intense and prone to generalize after activation of prelimbic cortex NMDA receptors
- Nicotine ameliorates NMDA receptor antagonist-induced deficits in contextual fear conditioning through high-affinity nicotinic acetylcholine receptors in the …
- Nitric oxide signalling in the basolateral complex of the amygdala: an extension of NMDA receptor activation during Pavlovian fear conditioning and expression
- NMDA and AMPA/kainate glutamatergic receptors in the prelimbic medial prefrontal cortex modulate the elaborated defensive behavior and innate fear-induced …
- NMDA and dopaminergic contributions to context fear memory reconsolidation
- NMDA and muscarinic receptor modulation of latent learning in Pavlovian fear conditioning.
- NMDA currents and receptor protein are downregulated in the amygdala during maintenance of fear memory
- NMDA GluN2A and GluN2B receptors play separate roles in the induction of LTP and LTD in the amygdala and in the acquisition and extinction of conditioned fear
- NMDA processes mediate anterograde amnesia of contextual fear conditioning induced by hippocampal damage: immunization against amnesia by context …
- NMDA receptor antagonism in the basolateral but not central amygdala blocks the extinction of Pavlovian fear conditioning in rats
- NMDA receptor antagonist MK-801 blocks learning of conditioned stimulus-unconditioned stimulus contiguity but not fear of conditioned stimulus in goldfish …
- NMDA receptor blockade and hippocampal neuronal loss impair fear conditioning and position habit reversal in C57Bl/6 mice
- NMDA receptor mediated expression of Arc in dorsal and ventral hippocampus contributes to the acquisition of contextual and trace fear conditioning
- NMDA receptor-and ERK-dependent histone methylation changes in the lateral amygdala bidirectionally regulate fear memory formation
- NMDA receptor-dependent LTD is required for consolidation but not acquisition of fear memory
- NMDA receptor-mediated Arc expression in dorsal and ventral hippocampus contributes to the acquisition of trace and contextual fear conditioning
- NMDA receptors and fear extinction: implications for cognitive behavioral therapy
- NMDA receptors and L-type voltage-gated calcium channels contribute to long-term potentiation and different components of fear memory formation in the lateral …
- NMDA receptors and the ontogeny of post‐shock and retention freezing during contextual fear conditioning
- NMDA receptors are critical for unleashing consolidated auditory fear memories
- NMDA receptors are essential for the acquisition, but not expression, of conditional fear and associative spike firing in the lateral amygdala
- NMDA receptors in retrosplenial cortex are necessary for retrieval of recent and remote context fear memory
- NMDA receptors in the CeA and BNST differentially regulate fear conditioning to predictable and unpredictable threats
- NMDA receptors in the pontine brainstem are necessary for fear potentiation of the startle response
- NMDA-mediated social learning of fear-induced conditioned analgesia to biting flies
- NR2A-and NR2B-containing NMDA receptors in the prelimbic medial prefrontal cortex differentially mediate trace, delay, and contextual fear conditioning
- NR2B subunit-specific NMDA antagonist Ro25-6981 inhibits the expression of conditioned fear: a comparison with the NMDA antagonist MK-801 and fluoxetine
- PACAP modulates the consolidation and extinction of the contextual fear conditioning through NMDA receptors
- Pharmacological evidence that a failure to recruit NMDA receptors contributes to impaired fear extinction retention in adolescent rats
- Plasticity of NMDA receptors at Ventral Hippocampal Synapses in the Infralimbic Cortex Regulates Cued fear
- Potentiation of GluN2C/D NMDA receptor subtypes in the amygdala facilitates the retention of fear and extinction learning in mice
- Pre-training prevents context fear conditioning deficits produced by hippocampal NMDA receptor blockade
- Prefrontal NMDA receptors expressed in excitatory neurons control fear discrimination and fear extinction
- Prenatal kynurenine exposure in rats: age-dependent changes in NMDA receptor expression and conditioned fear responding
- Pretraining NMDA receptor blockade in the basolateral complex, but not the central nucleus, of the amygdala prevents savings of the conditional fear.
- Role of NMDA receptors and MAP kinase in the amygdala in extinction of fear: clinical implications for exposure therapy
- ROLE OF PREFRONTAL CORTICAL NMDA NR2B SUBTYPE receptor IN fear-AND WORKING-MEMORY
- Role of the basolateral amygdala and NMDA receptors in higher-order conditioned fear
- Role of the basolateral amygdala and NMDA receptors in the acquisition and extinction of higher-order conditioned fear
- Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory
- Second-order fear conditioning prevented by blocking NMDA receptors in amygdala
- Studies of GluN2C-containing NMDA receptors in schizophrenia-like behaviors and fear learning; Relevance to the glutamate hypofunction hypothesis of …
- Surface expression of hippocampal NMDA GluN2B receptors regulated by fear conditioning determines its contribution to memory consolidation in adult rats
- Targeting the NMDA receptor for fear-related disorders
- Temporal-difference prediction errors and Pavlovian fear conditioning: role of NMDA and opioid receptors.
- The effect of hippocampal NMDA receptor blockade by MK-801 on cued fear extinction
- The effect of the mGlu5 negative allosteric modulator MTEP and NMDA receptor partial agonist D-cycloserine on Pavlovian conditioned fear
- The effect of the NMDA receptor antagonist MK-801 on the acquisition and extinction of learned fear in the developing rat
- The effects of intra-hippocampal microinfusion of D-cycloserine on fear extinction, and the expression of NMDA receptor subunit NR2B and neurogenesis in the …
- The expression of contextual fear conditioning involves activation of a NMDA receptor-nitric oxide-cGMP pathway in the dorsal hippocampus of rats
- The expression of contextual fear conditioning involves activation of an NMDA receptor–nitric oxide pathway in the medial prefrontal cortex
- The importance of having Arc: expression of the immediate-early gene Arc is required for hippocampus-dependent fear conditioning and blocked by NMDA receptor …
- The innate defensive behaviour and unconditioned fear-induced antinociception evoked by NMDA receptor activation in the medial hypothalamus are modulated by …
- The nitric oxide donor SIN-1-produced panic-like behaviour and fear-induced antinociception are modulated by NMDA receptors in the anterior hypothalamus
- The NMDA agonist D-cycloserine facilitates fear memory consolidation in humans
- The NMDA antagonist MK-801 blocks the extinction of Pavlovian fear conditioning.
- The NMDA receptor antagonist MK-801 renders pavlovian fear conditioning state-dependent
- The role of dorsal hippocampus and basolateral amygdala NMDA receptors in the acquisition and retrieval of context and contextual fear memories.
- The role of GluN2B-containing NMDA receptors in short-and long-term fear recall
- The role of NMDA glutamate receptors, PKA, MAPK, and CAMKII in the hippocampus in extinction of conditioned fear
- Trace and contextual fear conditioning require neural activity and NMDA receptor-dependent transmission in the medial prefrontal cortex
- Trace fear conditioning depends on NMDA receptor activation and protein synthesis within the dorsal hippocampus of mice
- US habituation, like CS extinction, produces a decrement in conditioned fear responding that is NMDA dependent and subject to renewal and reinstatement
- Vagus nerve stimulation enhances extinction of conditioned fear in rats and modulates Arc protein, CaMKII, and GluN2B-containing NMDA receptors in the …
- Vorinostat ameliorates impaired fear extinction possibly via the hippocampal NMDA-CaMKII pathway in an animal model of posttraumatic stress disorder
- Vorinostat, a histone deacetylase inhibitor, facilitates fear extinction and enhances expression of the hippocampal NR2B-containing NMDA receptor gene
