The ketogenic diet is a high-fat, adequate-protein, low-carbohydrate diet that in medicine is used primarily to treat difficult-to-control (refractory) epilepsy in children. The diet forces the body to burn fats rather than carbohydrates. Normally, the carbohydrates contained in food are converted into glucose, which is then transported around the body and is particularly important in fueling brain function. However, if little carbohydrate remains in the diet, the liver converts fat into fatty acids and ketone bodies. The ketone bodies pass into the brain and replace glucose as an energy source. An elevated level of ketone bodies in the blood, a state known as ketosis, leads to a reduction in the frequency of epileptic seizures.[1] Around half of children and young people with epilepsy who have tried some form of this diet saw the number of seizures drop by at least half, and the effect persists even after discontinuing the diet.[2] Some evidence indicates that adults with epilepsy may benefit from the diet, and that a less strict regimen, such as a modified Atkins diet, is similarly effective.[1] Potential side effects may include constipation, high cholesterol, growth slowing, acidosis, and kidney stones.[3] The original therapeutic diet for paediatric epilepsy provides just enough protein for body growth and repair, and sufficient calories[Note 1] to maintain the correct weight for age and height. The classic therapeutic ketogenic diet was developed for treatment of paediatric epilepsy in the 1920s and was widely used into the next decade, but its popularity waned with the introduction of effective anticonvulsant medications. This classic ketogenic diet contains a 4:1 ratio by weight of fat to combined protein and carbohydrate. This is achieved by excluding high-carbohydrate foods such as starchy fruits and vegetables, bread, pasta, grains, and sugar, while increasing the consumption of foods high in fat such as nuts, cream, and butter.[1] Most dietary fat is made of molecules called long-chain triglycerides (LCTs). However, medium-chain triglycerides (MCTs)—made from fatty acids with shorter carbon chains than LCTs—are more ketogenic. A variant of the classic diet known as the MCT ketogenic diet uses a form of coconut oil, which is rich in MCTs, to provide around half the calories. As less overall fat is needed in this variant of the diet, a greater proportion of carbohydrate and protein can be consumed, allowing a greater variety of food choices.[4][5] In 1994, Hollywood producer Jim Abrahams, whose son's severe epilepsy was effectively controlled by the diet, created the Charlie Foundation for Ketogenic Therapies to further promote diet therapy. Publicity included an appearance on NBC's Dateline program and ...First Do No Harm (1997), a made-for-television film starring Meryl Streep. The foundation sponsored a research study, the results of which—announced in 1996—marked the beginning of renewed scientific interest in the diet.[1] Possible therapeutic uses for the ketogenic diet have been studied for many additional neurological disorders, some of which include: Alzheimer's disease, amyotrophic lateral sclerosis, headache, neurotrauma, pain, Parkinson's disease, and sleep disorders.[6] - wiki SCIENTIFIC STUDIES 10 Graphs That Show The Power Of A Ketogenic Diet 10 Patients, 10 Years–Long Term Follow-Up Of Cardiovascular Risk Factors In Glut1 Deficiency Treated With Ketogenic Diet Therapies: A Prospective, Multicenter … 10 Questions About The Ketogenic Diet 113 Ketogenic Diet Services At Children'S Hospital Across The United Kingdom 31P-Nmr Study Of Brain Metabolism In The Rat Model Of The Ketogenic Diet 3T
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a form of programmed cell death that occurs in multicellular organisms.[2] Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, chromosomal DNA fragmentation, and global[vague] mRNA decay. The average adult human loses between 50 and 70 billion cells each day due to apoptosis.[3][a] For an average human child between the ages of 8 to 14 years old approximately 20 to 30 billion cells die per day.[5] In contrast to necrosis, which is a form of traumatic cell death that results from acute cellular injury, apoptosis is a highly regulated and controlled process that confers advantages during an organism's life cycle. For example, the separation of fingers and toes in a developing human embryo occurs because cells between the digits undergo apoptosis. Unlike necrosis, apoptosis produces cell fragments called apoptotic bodies that phagocytic cells are able to engulf and remove before the contents of the cell can spill out onto surrounding cells and cause damage to them.[6] Because apoptosis cannot stop once it has begun, it is a highly regulated process. Apoptosis can be initiated through one of two pathways. In the intrinsic pathway the cell kills itself because it senses cell stress, while in the extrinsic pathway the cell kills itself because of signals from other cells. Weak external signals may also activate the intrinsic pathway of apoptosis.[7] Both pathways induce cell death by activating caspases, which are proteases, or enzymes that degrade proteins. The two pathways both activate initiator caspases, which then activate executioner caspases, which then kill the cell by degrading proteins indiscriminately. Research on apoptosis has increased substantially since the early 1990s. In addition to its importance as a biological phenomenon, defective apoptotic processes have been implicated in a wide variety of diseases. Excessive apoptosis causes atrophy, whereas an insufficient amount results in uncontrolled cell proliferation, such as cancer. Some factors like Fas receptors and caspases promote apoptosis, while some members of the Bcl-2 family of proteins inhibit apoptosis. - wiki SCIENTIFIC STUDIES Mitochondria and Apoptosis Apoptosis Signaling Apoptosis and disease The biochemistry of Apoptosis Mitochondrial control of Apoptosis Apoptosis in cancer Apoptosis by Death Factor Apoptosis in development Apoptosis in AIDS Caspases: the executioners of Apoptosis. Dysregulation of Apoptosis in Cancer Mechanisms of Apoptosis Defining Apoptosis. Apoptosis: Molecular Regulation of Cell Death Neural Apoptosis p53-Dependent Apoptosis pathways Apoptosis in neurodegenerative disorders Calcium orchestrates Apoptosis Apoptosis and carcinogenesis. An evolutionary perspective on Apoptosis Apoptosis - the p53 network Apoptosis in the nervous system JNK signaling in Apoptosis Mitochondria and Apoptosis Apoptosis: an overview Apoptosis-based therapies PI3K: Downstream AKTion Blocks Apoptosis A model for p53-induced Apoptosis Apoptosis regulators. Cell Death: The Significance of Apoptosis Oxidative stress as a mediator of Apoptosis Ceramide: an intracellular signal for Apoptosis Oxidative stress and Apoptosis Apoptosis—an introduction Gonadal cell Apoptosis. Viruses and Apoptosis Mitochondrial dynamics and Apoptosis Mitochondrial control of nuclear Apoptosis Ischemia-induced neuronal Apoptosis Cytochrome C-Mediated Apoptosis Inhibition of Macroautophagy Triggers Apoptosis The molecular biology of Apoptosis Molecular characterization of mitochondrial Apoptosis-inducing factor S-nitrosylation regulates Apoptosis Apoptosis, autophagy, and more Angiogenesis and Apoptosis IAP family proteins—suppressors of Apoptosis Placental Apoptosis in preeclampsia Emerging roles of caspase-3 in Apoptosis Apoptosis
Urolithin A … emblica L.) Fruits Ameliorate Vascular Smooth Muscle Cell Dysfunction in Hyperglycemia: An Underlying Mechanism Involved in Ellagitannin Metabolite Urolithin A A natural molecule, Urolithin A, downregulates androgen receptor activation and suppresses growth of prostate cancer A Novel Candidate for Prevention and Treatment of Atherosclerosis: Urolithin B Decreases Lipid Plaque Deposition in apoE−/− Mice and Increases Early Stages of … Activation of the miR-34a-Mediated SIRT1/mTOR Signalling Pathway by Urolithin A Attenuates D-Galactose-Induced Brain Aging in Mice An increased autophagic flux contributes to the anti-inflammatory potential of Urolithin A in macrophages Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism Antiaging Effects of Urolithin A on Replicative Senescent Human Skin Fibroblasts Antimelanogenic effect of Urolithin A and urolithin B, the colonic metabolites of ellagic acid, in B16 melanoma cells Antiproliferative activity of the ellagic acid-derived gut microbiota isoUrolithin A and comparison with its Urolithin A isomer: the role of cell metabolism Antiproliferative activity of the ellagic acid-derived gut microbiota isoUrolithin A and comparison with its Urolithin A isomer: the role of cell metabolism Antiproliferative effect of Urolithin A, the ellagic acid-derived colonic metabolite, on hepatocellular carcinoma HepG2. 2.15 cells by targeting Lin28a/let-7a axis Bioactivity screening for xylopic acid, geraniin and its gut metabolites, ellagic acid and Urolithin A, in cell based assays Chemoprevention of endometrial cancer with Urolithin A, a metabolite of berry ellagitannins. Clustering according to urolithin metabotype explains the interindividual variability in the improvement of cardiovascular risk biomarkers in overweight‐obese … Compositions comprising nicotinamide riboside and a urolithin Development and validation of a liquid chromatography-electrospray ionization-tandem mass spectrometry method for the determination of urolithin C in rat plasma … Effects of fruit ellagitannin extracts, ellagic acid, and their colonic metabolite, Urolithin A, on Wnt signaling Effects of Pomegranate Extract on High Fat/High Sucrose Diet induced Obesity are Dependent on the Intestinal Formation of Urolithin A Ellagic acid and its metabolite Urolithin A induce prostate cancer cell death in p53 dependent and independent manner Ellagic Acid and Its Microbial Metabolite Urolithin A Alleviate Diet-induced Insulin Resistance in Mice (OR24-03-19) Ellagic Acid and Urolithin A Improve Insulin Sensitivity in Diet-Induced Insulin Resistant Mice and Reduce Detrimental Effects of Palmitate Administration in … Ellagitannin metabolites, Urolithin A glucuronide and its aglycone Urolithin A, ameliorate TNF--induced inflammation and associated molecular markers in … Ellagitannin metabolites, Urolithin A glucuronide and its aglycone Urolithin A, ameliorate TNF‐α‐induced inflammation and associated molecular markers in human … Enhancement of gut barrier function by microbial metabolite, Urolithin A via AhR-Nrf2 dependent pathways in IBD Genetic Polymorphisms, Adherence to Mediterranean Diet and Microbiota-Associated Urolithin Metabotypes: A Complex Cocktail to Predict the Obesity in Childhood … Gordonibacter urolithinfaciens sp. nov., a urolithin-producing bacterium isolated from the human gut Gut bacterial metabolite Urolithin A (UA) mitigates Ca2+ entry in T cells by regulating miR-10a-5p Gut microbiota conversion of dietary ellagic acid into bioactive phytoceutical Urolithin A inhibits heme peroxidases Identification of Novel Urolithin Metabolites
Honokiol Simple Lignans Of The Cphephec Kind Are Illustrated By The Antibacterials Honokiol And The Protein Kinase A Bisphenolic Honokiol Analog Outcompetes Oral Antimicrobial Agent Cetylpyridinium Chloride Via A Membrane-Associated Mechanism A Cocktail Of Betulinic Acid, Parthenolide, Honokiol And Ginsenoside Rh2 In Liposome Systems For Lung Cancer Treatment A Concise Synthesis Of 4′-O-Methyl Honokiol A Concise Synthesis Of Honokiol A Facile Graphene Nanosheets‐Based Electrochemical Sensor For Sensitive Detection Of Honokiol In Traditional Chinese Medicine A Naturally Occurring Rexinoid, Honokiol, Can Serve As A Regulator Of Various Retinoid X Receptor Heterodimers A Novel Composite Drug Delivery System: Honokiol Nanoparticles In Thermosensitive Hydrogel Based On Chitosan A Novel Gsh Responsive Poly (Alpha-Lipoic Acid) Nanocarrier Bonding With The Honokiol-Dmxaa Conjugate For Combination Therapy A Novel Honokiol Liposome: Formulation, Pharmacokinetics, And Antitumor Studies A Novel Sensing Platform Based On Ionic Liquid Integrated Carboxylic-Functionalized Graphene Oxide Nanosheets For Honokiol Determination A Novel Transdermal Honokiol Formulation Based On Pluronic F127 Copolymer A Short And Efficient Synthesis Of Honokiol Via Claisen Rearrangement A Simultaneous Determination Of Honokiol And Magnolol In Oriental Pharmaceutical Decoctions Containing Magnolia Bark By Ion-Pair High-Performance Liquid … A Study On Extracting And Determining Magnolol And Honokiol In Huoxiang Zhengqi Troche A Study On The Extracting And Determining Method For Magnolol And Honokiol In Muxiang Shunqi Pills [J] A Study On The Ultrasonic Extraction For Magnolol And Honokiol In Leaves Of Magnolia Offcinalis Rend Et Wils A Validated Ultra-Hplc–Ms/Ms Method For Determination Of Honokiol In Human Plasma And Its Application To A Clinical Pharmacokinetic Study Abrogation Of Established Inflammatory Arthritis By The Gabaa Agonist Honokiol.(50.18) Absorptive Feature Of Honokiol And Magnolol In The Rat′ S Intestines [J] Abstract A134: Honokiol Targets Stat3 In Head And Neck Squamous Cell Carcinoma Abstract B02: Honokiol Attenuates Stemness, Growth And Metastasis Of Pancreatic Tumor Cells: A Novel Natural Agent For Therapy And Prevention Abstract C46: The Pharmacokinetics And Pharmacodynamics Study Of Honokiol In Sprague-Dawley Rats And Colorectal Tumor-Bearing Mice Abstract Lb-187: Novel Mechanistic Insights Into The Bioactive Compound Honokiol-Mediated Inhibition Of Epithelial To Mesenchymal Transition In Breast Cancer … Abstract Lb-61: Inhibiting “Dedifferentiation” In Breast Cancer Cells Using Honokiol-A Plant Derived Polyphenol Abstract# 2975: Honokiol, A Natural Product, Induces G1-Phase Cell Cycle Arrest And Caspase-3-Dependent Apoptosis In Human Non-Small Cell Lung Cancer Cells Abstract# 925: Chemopreventive Effects Of Honokiol On Uv-B Induced Skin Cancer Development Activation Of Tumor Suppressor Lkb1 By Honokiol Abrogates Cancer Stem-Like Phenotype In Breast Cancer Via Inhibition Of Oncogenic Stat3 Acute And Subchronic Toxicities In Dogs And Genotoxicity Of Honokiol Microemulsion Acute And Sub-Chronic Toxicity Studies Of Honokiol Microemulsion Advances On Semisynthesis, Total Synthesis, And Structure-Activity Relationships Of Honokiol And Magnolol Derivatives An Electrochemical Sensor For Honokiol Based On A Glassy Carbon Electrode Modified With Mos 2/Graphene Nanohybrid Film An Expedient Synthesis Of Honokiol And Its Analogues As Potential Neuropreventive Agents Analysis Of Magnolol And Honokiol In Biological Fluids By Capillary Zone Electrophoresis Analysis Of Magnolol And Honokiol In Traditional Chinese Drug Hoe-Po Analysis Of Β-Eudesmolmagnolol And Honokiol In Magnolia Officinalis By Ptgc
Zerumbone Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio Antitumor activity of extract of Zingiber aromaticum and its bioactive sesquiterpenoid Zerumbone Studies in sesquiterpenes—XVI: Zerumbone, a monocyclic sesquiterpene ketone Zerumbone, a sesquiterpene in subtropical ginger, suppresses skin tumor initiation and promotion stages in ICR mice Anti-inflammatory effect of Zerumbone on acute and chronic inflammation models in mice Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary Zerumbone isolated from Zingiber zerumbet Zerumbone induces apoptosis in T-acute lymphoblastic leukemia cells In vitro ultramorphological assessment of apoptosis induced by Zerumbone on (HeLa) Zerumbone-loaded nanostructured lipid carriers: preparation, characterization, and antileukemic effect Zerumbone, an HIV-inhibitory and cytotoxic sesquiterpene of Zingiber aromaticum and Z. zerumbet Anticancer and antimicrobial activities of Zerumbone from Characterization of the inclusion complex of Zerumbone with hydroxypropyl-β-cyclodextrin Chemistry of Zerumbone. 2. Regulation of ring bond cleavage and unique antibacterial activities of Zerumbone derivatives Preliminary analysis of the antinociceptive activity of Zerumbone Zerumbone abolishes NF-κB and IκBα kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis … Antitumor effects of Zerumbone from Zingiber zerumbet in P-388D1 cells in vitro and in vivo Attractive reactivity of a natural product, Zerumbone Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation … Zerumbone down-regulates chemokine receptor CXCR4 expression leading to inhibition of CXCL12-induced invasion of breast and pancreatic tumor cells Suppression of dextran sodium sulfate-induced colitis in mice by Zerumbone, a subtropical ginger sesquiterpene, and nimesulide: separately and in combination Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive … Zerumbone, a bioactive sesquiterpene, induces G2/M cell cycle arrest and apoptosis in leukemia cells via a Fas‐and mitochondria‐mediated pathway Key cell signaling pathways modulated by Zerumbone: role in the prevention and treatment of cancer Nuclear magnetic resonance spectroscopy. The conformational mobility of humulene and Zerumbone In vitro covalent binding proteins of Zerumbone, a chemopreventive food factor Zerumbone inhibits tumor angiogenesis via NF-κB in gastric cancer Chemistry of Zerumbone. 1. Simplified isolation, conjugate addition reactions, and a unique ring contracting transannular reaction of its dibromide Zerumbone inhibits interleukin-6 and induces apoptosis and cell cycle arrest in ovarian and cervical cancer cells Zerumbone abolishes RANKL-induced NF-κB activation, inhibits osteoclastogenesis, and suppresses human breast cancer–induced bone loss in athymic nude mice Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by Zerumbone from the rhizomes of the … Zerumbone, a Southeast Asian ginger sesquiterpene, induced apoptosis of pancreatic carcinoma cells through p53 signaling pathway Anticancer activity of natural compound (Zerumbone) extracted from Zingiber zerumbet in human HeLa cervical cancer cells The chemistry of Zerumbone. Part 5: Structural transformation of the dimethylamine derivatives Antibacterial and antimutagenic activities of novel Zerumbone analogues Zerumbone, an anti‐inflammatory phytochemical, induces expression of proinflammatory cytokine genes in human colon adenocarcinoma cell
Withaferin A (Ashwaganda) 2, 3-Dihydro-3β-methoxy Withaferin-A Protects Normal Cells against Stress: Molecular Evidence of Its Potent Cytoprotective Activity 2, 3-Dihydrowithaferin A-3β-O-sulfate, a new potential prodrug of withaferin A from aeroponically grown Withania somnifera 3beta-methoxy derivation of Withaferin-a Attenuates its Anticancer potency: Bioinformatics and molecular evidences 5,6-De-epoxy-5-en-7-one-17-hydroxy withaferin A, a new cytotoxic steroid from Withania somnifera L. Dunal leaves A novel combination of withaferin A and sorafenib shows synergistic efficacy against both papillary and anaplastic thyroid cancers A novel combination of withaferin A and sulforaphane inhibits epigenetic machinery, cellular viability and induces apoptosis of breast cancer cells A rapid and simple high performance thin layer chromatographic method for simultaneous analysis of β-sitosterol-D-glucoside, gallic acid, withaferin A and withanolide A in Ashvagandharishta A Study on the efficacy of Withaferin-A in reducing oxidative stress against DEN induced hepatocellular carcinoma A validated and densitometric HPTLC method for the quantification of Withaferin-A and Withanolide-A in different plant parts of two morphotypes of Withania somnifera A110 THORACIC CANCERS: PATHOGENESIS AND NOVEL TARGETS: The Use Of Withaferin-A As An Anti-Metastatic Agent In Non-Small Cell Lung Cancer Abstract A10: Withaferin-A, a natural compound inhibits AKT-induced metastatic colorectal cancer Abstract A115: withaferin A downregulates her-2/neu protein expression in human breast cancer cells. Abstract A2-32: Identification of withaferin A as a novel cancer stem cell inhibitor to overcome drug resistance in non-small cell lung carcinoma Abstract A29: Targeting adenylate kinase-4 modulation of HIF-1α: Stability identifies Withaferin-A suppresses lung cancer metastasis Abstract A4: withaferin A induces apoptosis in imatinib-resistant CML cells by repressing the Akt signaling pathway Abstract A48: Ovarian tumor-induced immunosuppression of NK cells and its prevention by dietary supplementation of herbal withaferin A (Ashwagandha). Abstract B41: withaferin A promotes ROS-mediated differentiation of neuroblastoma Abstract B57: A natural plant-derived compound, withaferin A, exploits the stress pathway to induce antitumor immunity. Abstract B84: Withaferin‐A is a novel HSF‐1 inhibitor with potent antitumor effects in melanoma in vivo Abstract C218: Novel therapeutic potential in targeting micro tubules by naturally occurring anti cancer agent withaferin A in human cancers. Abstract LB-113: A novel role of withaferin A as an effective pro-apoptotic receptor agonist (PARA) and insights into the underlying molecular mechanisms Abstract LB-154: Epigenetic silencing of triple-negative breast cancer hallmarks by withaferin A Abstract NTOC-100: OVARIAN TUMOR-ASSOCIATED GRP78 INDUCES IMMUNOSUPPRESSION AND withaferin A (ASHWAGANDHA) ENHANCES ANTI … Abstract P2-09-12: withaferin A-mediated inhibition of breast carcinoma involves concomitant activation of CHOP and Elk1 via ERK/ribosomal S6 kinase (RSK) … Abstract# 3903: Inhibition of human cervical cancer cell growth by withaferin A and potential mechanisms Actin microfilament aggregation induced by withaferin A is mediated by annexin II Activation of signal transducer and activator of transcription 3 fails to confer resistance against withaferin A-induced apoptosis in human breast cancer cells Age related differences in stress-induced neurobehavioral patterns in rats modulated by withaferin-A and other antioxidants Agrobacterium rhizogenes mediated hairy root culture system of Withania somnifera L Dunal for withaferin A production Ameliorative effect of withaferin A on ageing-mediated impairment in the dopamine system and its
Ursolic Acid 23-Hydroxy Ursolic acid Protects Atherosclerosis-Prone Mice From Monocyte Dysfunction 27-O-(E)-P-Coumaric Acyl Ursolic acid Via Jnk/Sapk Signal Pathway Regulates Apoptosis Of Human Breast Cancer Mda-Mb-231 Cell Line 27-P-Cumaroxy-Ursolsäure, Ein Neuer Inhaltsstoff Von Ilex Aquifolium L.[1]/27-P-Cumaroxy Ursolic acid-A New Constituent Of Ilex Aquifolium L.[1] 2D Raman Spectroscopy As An Alternative Technique For Distinguishing Oleanoic Acid And Ursolic acid 3D-Qsar And Docking Studies On Ursolic acid Derivatives For Anticancer Activity Based On Bladder Cell Line T24 Targeting Nf-Kb Pathway Inhibition 858. Triterpenoids From New Zealand Plants. Isolation Of Ursolic acid From Gaultheria Subcorymbosa Col. A Bioinformatic And Mechanistic Study Elicits The Antifibrotic Effect Of Ursolic acid Through The Attenuation Of Oxidative Stress With The Involvement Of Erk, Pi3K … A Comparative Study For The Extraction Methods And Solvent Selection For Isolation, Quantitative Estimation And Validation Of Ursolic acid In The Leaves Of … A Comparative Study Of The Separation Of Oleanolic Acid And Ursolic acid In Prunella Vulgaris By High-Performance Liquid Chromatography And Cyclodextrin-Modified … A Comparative Study On The Isolation And Cerium (Iv) Ammonium Nitrate Mediated Oxidative Transformation Of Oleanolic Acid And Ursolic acid A Comparison Of The Effects Of Ursolic acid And L-Leucine Supplementation On Igf-1 Receptor And Akt-Mtor Signaling In Response To Resistance Exercise In Trained … A Convenient Separation Of Ursolic And Oleanolic Acid A functionalized multi-walled carbon nanotube-based composite monolith as a solid-phase extraction adsorbent for on-line purification and enrichment of Ursolic acid in medicinal plants A High Content Drug Screen Identifies Ursolic acid As An Inhibitor Of Amyloid Β Protein Interactions With Its Receptor Cd36 A Hydrophilic Conjugate Approach Toward The Design And Synthesis Of Ursolic acid Derivatives As Potential Antidiabetic Agent A Metal Organic Framework Polymer Monolithic Column As A Novel Adsorbent For On-Line Solid Phase Extraction And Determination Of Ursolic acid In Chinese Herbal … A Myrtus Communis Extract Enriched In Myrtucummulones And Ursolic acid Reduces Resistance Of Propionibacterium Acnes Biofilms To Antibiotics Used In Acne … A New Synthetic Ursolic acid Derivative Iua With Anti-Tumor Efficacy Against Osteosarcoma Cells Via Inhibition Of Jnk Signaling Pathway A Novel Co-Drug Of Aspirin And Ursolic acid Interrupts Adhesion, Invasion And Migration Of Cancer Cells To Vascular Endothelium Via Regulating Emt And Egfr … A Novel Form Of Melanoma Apoptosis Resistance: Melanogenesis Up-Regulation In Apoptotic B16-F0 Cells Delays Ursolic acid-Triggered Cell Death A Novel Synthetic Ursolic acid Derivative Inhibits Growth And Induces Apoptosis In Breast Cancer Cell Lines A Pentacyclic Triterpene Natural Product, Ursolic acid And Its Prodrug Us597 Inhibit Targets Within Cell Adhesion Pathway And Prevent Cancer Metastasis A Phase I Pharmacokinetic Study Of Ursolic acid Nanoliposomes In Healthy Volunteers And Patients With Advanced Solid Tumors A Phase I Trial To Evaluate The Multiple-Dose Safety And Antitumor Activity Of Ursolic acid Liposomes In Subjects With Advanced Solid Tumors A Preliminary Investigation Of Ursolic acid In Cell Suspension Culture Of Salvia Officinalis A Rapid Tandem Mass Spectrometric Assay For Determination Of Ursolic acid–Application To Analysis Of Ursolic acid In Four Species Of Staphylea L. And
Thymoquinone Thymoquinone is a potent superoxide anion scavenger Hepatoprotective activity of Thymoquinone in isolated rat hepatocytes Thymoquinone: potential cure for inflammatory disorders and cancer Thymoquinone: a promising anti-cancer drug from natural sources Fixed oil of Nigella sativa and derived Thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation The influence of Thymoquinone on doxorubicin-induced hyperlipidemic nephropathy in rats Thymoquinone and its therapeutic potentials Thymoquinone protects against carbon tetrachloride hetatotoxicity in mice via an antioxidant mechanism Inhibitory effects of Thymoquinone against 20-methylcholanthrene-induced fibrosarcoma tumorigenesis. In vitro toxicological properties of Thymoquinone Antinociceptive effects of Nigella sativa oil and its major component, Thymoquinone, in mice Effects of Thymoquinone (volatile oil of black cumin) on rheumatoid arthritis in rat models Thymoquinone protects against experimental colitis in rats Anticonvulsant effects of Thymoquinone, the major constituent of Nigella sativa seeds, in mice Antitumor activity of gemcitabine and oxaliplatin is augmented by Thymoquinone in pancreatic cancer Acute and subchronic toxicity of Thymoquinone in mice Thymoquinone protects against doxorubicin-induced cardiotoxicity without compromising its antitumor activity. Inhibition of benzo (a) pyrene-induced forestomach carcinogenesis in mice by Thymoquinone. In Vitro acetylcholinesterase inhibitory properties of thymol, carvacrol and their derivatives Thymoquinone and thymohydroquinone Review on molecular and therapeutic potential of Thymoquinone in cancer Oral and intraperitoneal LD50 of Thymoquinone, an active principle of Nigella sativa, in mice and rats Improvement of experimental allergic encephalomyelitis (EAE) by Thymoquinone; an oxidative stress inhibitor. Thymoquinone reduces hepatic glucose production in diabetic hamsters In vitro inhibition of growth and induction of apoptosis in cancer cell lines by Thymoquinone Thymoquinone suppresses expression of inducible nitric oxide synthase in rat macrophages Androgen receptor–and E2F-1–targeted Thymoquinone therapy for hormone-refractory prostate cancer Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways Neuroprotective effects of Thymoquinone against transient forebrain ischemia in the rat hippocampus Anti-inflammatory effect of Thymoquinone in a mouse model of allergic lung inflammation Protective effects of Thymoquinone and desferrioxamine against hepatotoxicity of carbon tetrachloride in mice Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity Thymoquinone-in-rats/" target="_blank" rel="noopener" data-saferedirecturl="https://www.google.com/url?hl=en&q=https://vlibrary.emro.who.int/imemr/a-study-of-the-anti-inflammatory-activity-of-nigella-sativa-l-and-Thymoquinone-in-rats/&source=gmail&ust=1578765043452000&usg=AFQjCNEz35n-wi7Hac9DaSgvN3Tu5YC5bA">Study of the anti-inflammatory activity of Nigella sativa L and Thymoquinone in rats, Saudi Pharm Anti-inflammatory effects of the Nigella sativa seed extract, Thymoquinone, in pancreatic cancer cells Antidermatophyte activity of ether extract of Nigella sativa and its active principle, Thymoquinone Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism Reactive oxygen species mediate Thymoquinone-induced apoptosis and activate ERK and JNK signaling Nigella sativa oil, nigellone and derived Thymoquinone inhibit synthesis of 5-lipoxygenase products in polymorphonuclear leukocytes from rats Thymoquinone attenuates diethylnitrosamine induction of hepatic carcinogenesis through antioxidant signaling Effects of alpha-hederin and Thymoquinone, constituents of Nigella sativa, on human cancer cell lines Nonenzymatic reduction of Thymoquinone in physiological conditions Thymoquinone attenuates ifosfamide-induced Fanconi syndrome in rats and enhances its antitumor activity in mice Lack of p53 augments Thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells Targeting nuclear factor-κB activation pathway by Thymoquinone: role in suppression
Sulforaphane Anticarcinogenic activities of Sulforaphane and structurally related synthetic norbornyl isothiocyanates. Multi-targeted prevention of cancer by Sulforaphane Molecular basis for chemoprevention by Sulforaphane: a comprehensive review Identification of Nrf2-regulated genes induced by the chemopreventive agent Sulforaphane by oligonucleotide microarray A novel mechanism of chemoprotection by Sulforaphane: inhibition of histone deacetylase Sulforaphane treatment of autism spectrum disorder (ASD) Nuclear factor κB is a molecular target for Sulforaphane-mediated anti-inflammatory mechanisms Sulforaphane as a promising molecule for fighting cancer Chemoprotection by Sulforaphane: keep one eye beyond Keap1 Protective effect of Sulforaphane against oxidative stress: recent advances Molecular targets of dietary phenethyl isothiocyanate and Sulforaphane for cancer chemoprevention Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells Antimetastatic activity of Sulforaphane Potent induction of phase 2 enzymes in human prostate cells by Sulforaphane Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apcmin mice Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents Comparison of the bioactivity of two glucoraphanin hydrolysis products found in broccoli, Sulforaphane and Sulforaphane nitrile Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent Sulforaphane Preclinical and clinical evaluation of Sulforaphane for chemoprevention in the breast Heating decreases epithiospecifier protein activity and increases Sulforaphane formation in broccoli Keap1–nrf2 signaling: a target for cancer prevention by Sulforaphane Dietary Sulforaphane, a histone deacetylase inhibitor for cancer prevention Chemoprevention of colonic aberrant crypt foci in Fischer rats by Sulforaphane and phenethyl isothiocyanate Modification of keap1 cysteine residues by Sulforaphane Sulforaphane induces cell type–specific apoptosis in human breast cancer cell lines Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo [a] pyrene-induced stomach tumors A Sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway Sulforaphane suppressed LPS-induced inflammation in mouse peritoneal macrophages through Nrf2 dependent pathway Identification of sensor cysteines in human Keap1 modified by the cancer chemopreventive agent Sulforaphane Electrophilic tuning of the chemoprotective natural product Sulforaphane Disposition of glucosinolates and Sulforaphane in humans after ingestion of steamed and fresh broccoli Sulforaphane as a potential protective phytochemical against neurodegenerative diseases Sulforaphane and its metabolite mediate growth arrest and apoptosis in human prostate cancer cells Thermal degradation of Sulforaphane in aqueous solution Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines Oral Sulforaphane increases Phase II antioxidant enzymes in the human upper airway Sulforaphane and its glutathione conjugate but not Sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in … Sulforaphane targets pancreatic tumour-initiating cells by NF-κB-induced antiapoptotic signalling Discovery and development of Sulforaphane as a cancer chemopreventive phytochemical1 Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species Sulforaphane improves cognitive function administered following traumatic brain injury Sulforaphane causes autophagy to inhibit release of cytochrome C and apoptosis in human prostate cancer cells Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3
Solidago virgaurea Study of the anti-inflammatory activity of Populus tremula, Solidago virgaurea and Fraxinus excelsior. A combination of Populus tremula, Solidago virgaurea and Fraxinus excelsior as an anti-inflammatory and antirheumatic drug. A short review. In vivo anti-inflammatory activity of caffeoylquinic acid derivatives from Solidago virgaurea in rats Anti-inflammatory effects of Populus tremula, Fraxinus excelsior, Solidago virgaureaextracts and their combination Phytodolor® in human monocytes … -inflammatory drug: investigations into the cyto-and molecular pharmacology for a better understanding of the anti-inflammatory activity of preparations from Solidago … … and clinical effectiveness of a fixed phytogenic combination trembling poplar (Populus tremula), true goldenrod (Solidago virgaurea) and ash (Fraxinus excelsior) in … … drug: investigations into the cyto-and molecular pharmacology for a better understanding of the anti-inflammatory activity of preparations from Solidago virgaurea. … Korean natural products for anti-adipogenesis properties and isolation of kaempferol-3-O-rutinoside as a potent anti-adipogenetic compound from Solidago virgaurea A Case of Abnormal Flower Structures connected with Reduced Fertility in Solidago virgaurea L. A combination of Populus tremula, Solidago virgaurea and Fraxinus excelsior as an anti-inflammatory and antirheumatic drug. A short review. Abundance and diversity of arbuscular mycorrhizal fungi in invasive Solidago canadensis and indigenous S. virgaurea Analytical Method for the Validation of Three Polyphenols as a Marker Compound for the Standardization of Solidago virgaurea subsp. gigantea Extracts and … Anti-inflammatory effects of Populus tremula, Fraxinus excelsior, Solidago virgaurea extracts and their combination Phytodolor® in human monocytes Anti-obesity effect of Solidago virgaurea var. gigantea extract through regulation of adipogenesis and lipogenesis pathways in high-fat diet-induced obese mice … Antibacterial and antimutagenic activity of extracts aboveground parts of three Solidago species: Solidago virgaurea L., Solidago canadensis L. and Solidago … Antibacterial clerodane diterpenes from goldenrod (Solidago virgaurea) Antimicrobial activity of Solidago virgaurea L. from in vitro cultures Antineoplastic activity of Solidago virgaurea on prostatic tumor cells in an SCID mouse model Antioxidant activity of goldenrod (Solidago virgaurea) leaf and stem powder on raw ground pork during chilled storage Antioxidant and antimicrobial activities of Solidago virgaurea extracts Antioxidative properties of Alchemilla xanthochlora, Salvia officinalis and Solidago virgaurea water extracts Antioxidative properties of alcoholic extracts from Fraxinus excelsior, Populus tremula and Solidago virgaurea. Assessment of allelopathic potential of Solidago virgaurea L. on some selected crops. Biochemical effects of Solidago virgaurea extract on experimental cardiotoxicity Biorefining of Bergenia crassifolia L., Fagopyrum esculentum Moench. and Solidago virgaurea L. by high pressure extraction methods and evaluation of obtained … Biorefining of goldenrod (Solidago virgaurea L.) leaves by supercritical fluid and pressurized liquid extraction and evaluation of antioxidant properties and main … Characterizing the Allergens Contained in goldenrod (Solidago virgaurea) Chromatographic fingerprint, antioxidant activity, and colour characteristic of polish goldenrod (Solidago virgaurea L.) honey and flower Competition for resources is ameliorated by niche differentiation between Solidago virgaurea life-history stages in the Arctic Constituents of the essential oil of Solidago virgaurea L. Development and characterization of EST‐SSR markers for the Solidago virgaurea complex (Asteraceae) in the Japanese archipelago Effect of agrotechnical factors on the yield of goldenrod (Solidago